LOCUS       DAIGQM010000001        74204 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.001, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000001 DAIGQM010000000
VERSION     DAIGQM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.001"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(606..962)
                     /locus_tag="NOA48_000001"
     CDS             complement(606..962)
                     /locus_tag="NOA48_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCI0788316.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOA48_000002"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOA48_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0788317.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1732..3918)
                     /locus_tag="NOA48_000003"
     CDS             complement(1732..3918)
                     /locus_tag="NOA48_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0788318.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4136..4819
                     /locus_tag="NOA48_000004"
     CDS             4136..4819
                     /locus_tag="NOA48_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCI0788319.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4900..5619)
                     /locus_tag="NOA48_000005"
     CDS             complement(4900..5619)
                     /locus_tag="NOA48_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0788320.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(5931..6137)
                     /locus_tag="NOA48_000006"
     CDS             complement(5931..6137)
                     /locus_tag="NOA48_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788321.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6382..6984
                     /locus_tag="NOA48_000007"
     CDS             6382..6984
                     /locus_tag="NOA48_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0788322.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            7125..8405
                     /locus_tag="NOA48_000008"
     CDS             7125..8405
                     /locus_tag="NOA48_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0788323.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8418..9146
                     /locus_tag="NOA48_000009"
     CDS             8418..9146
                     /locus_tag="NOA48_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788324.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(9215..10738)
                     /locus_tag="NOA48_000010"
     CDS             complement(9215..10738)
                     /locus_tag="NOA48_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0788325.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            10990..12171
                     /locus_tag="NOA48_000011"
     CDS             10990..12171
                     /locus_tag="NOA48_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0788326.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOA48_000012"
     CDS             complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOA48_000012"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCI0788327.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(14310..17021)
                     /locus_tag="NOA48_000013"
     CDS             complement(14310..17021)
                     /locus_tag="NOA48_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788328.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(17031..17732)
                     /locus_tag="NOA48_000014"
     CDS             complement(17031..17732)
                     /locus_tag="NOA48_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788329.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            17918..18517
                     /locus_tag="NOA48_000015"
     CDS             17918..18517
                     /locus_tag="NOA48_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0788330.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            18598..19611
                     /locus_tag="NOA48_000016"
     CDS             18598..19611
                     /locus_tag="NOA48_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0788331.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            19719..20636
                     /gene="rbsK"
                     /locus_tag="NOA48_000017"
     CDS             19719..20636
                     /gene="rbsK"
                     /locus_tag="NOA48_000017"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCI0788332.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDALDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            20664..21059
                     /gene="rbsD"
                     /locus_tag="NOA48_000018"
     CDS             20664..21059
                     /gene="rbsD"
                     /locus_tag="NOA48_000018"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCI0788333.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            21059..22432
                     /locus_tag="NOA48_000019"
     CDS             21059..22432
                     /locus_tag="NOA48_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0788334.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            22789..24933
                     /locus_tag="NOA48_000020"
     CDS             22789..24933
                     /locus_tag="NOA48_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0788335.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(24985..26025)
                     /locus_tag="NOA48_000021"
     CDS             complement(24985..26025)
                     /locus_tag="NOA48_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0788336.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26302..28104)
                     /locus_tag="NOA48_000022"
     CDS             complement(26302..28104)
                     /locus_tag="NOA48_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788337.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(28118..28870)
                     /locus_tag="NOA48_000023"
     CDS             complement(28118..28870)
                     /locus_tag="NOA48_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788338.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(28879..29241)
                     /locus_tag="NOA48_000024"
     CDS             complement(28879..29241)
                     /locus_tag="NOA48_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0788339.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(29417..30289)
                     /locus_tag="NOA48_000025"
     CDS             complement(29417..30289)
                     /locus_tag="NOA48_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0788340.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(30340..30828)
                     /locus_tag="NOA48_000026"
     CDS             complement(30340..30828)
                     /locus_tag="NOA48_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCI0788341.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(30966..31757)
                     /locus_tag="NOA48_000027"
     CDS             complement(30966..31757)
                     /locus_tag="NOA48_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCI0788342.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(31812..32420)
                     /locus_tag="NOA48_000028"
     CDS             complement(31812..32420)
                     /locus_tag="NOA48_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCI0788343.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(32413..32730)
                     /locus_tag="NOA48_000029"
     CDS             complement(32413..32730)
                     /locus_tag="NOA48_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0788344.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(32886..33614)
                     /locus_tag="NOA48_000030"
     CDS             complement(32886..33614)
                     /locus_tag="NOA48_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCI0788345.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            33773..34654
                     /locus_tag="NOA48_000031"
     CDS             33773..34654
                     /locus_tag="NOA48_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0788346.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(34891..35934)
                     /locus_tag="NOA48_000032"
     CDS             complement(34891..35934)
                     /locus_tag="NOA48_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0788347.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(35937..36605)
                     /locus_tag="NOA48_000033"
     CDS             complement(35937..36605)
                     /locus_tag="NOA48_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788348.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            36747..39083
                     /locus_tag="NOA48_000034"
     CDS             36747..39083
                     /locus_tag="NOA48_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0788349.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(39198..39509)
                     /locus_tag="NOA48_000035"
     CDS             complement(39198..39509)
                     /locus_tag="NOA48_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788350.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            39690..41165
                     /locus_tag="NOA48_000036"
     CDS             39690..41165
                     /locus_tag="NOA48_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCI0788351.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            41212..41796
                     /locus_tag="NOA48_000037"
     CDS             41212..41796
                     /locus_tag="NOA48_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCI0788352.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            41798..42217
                     /locus_tag="NOA48_000038"
     CDS             41798..42217
                     /locus_tag="NOA48_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCI0788353.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(42498..42782)
                     /locus_tag="NOA48_000039"
     CDS             complement(42498..42782)
                     /locus_tag="NOA48_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCI0788354.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(43134..43844)
                     /locus_tag="NOA48_000040"
     CDS             complement(43134..43844)
                     /locus_tag="NOA48_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCI0788355.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(43841..45313)
                     /locus_tag="NOA48_000041"
     CDS             complement(43841..45313)
                     /locus_tag="NOA48_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0788356.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            45451..45924
                     /locus_tag="NOA48_000042"
     CDS             45451..45924
                     /locus_tag="NOA48_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0788357.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(46077..46628)
                     /locus_tag="NOA48_000043"
     CDS             complement(46077..46628)
                     /locus_tag="NOA48_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0788358.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            46733..47263
                     /locus_tag="NOA48_000044"
     CDS             46733..47263
                     /locus_tag="NOA48_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCI0788359.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(47746..48189)
                     /locus_tag="NOA48_000045"
     CDS             complement(47746..48189)
                     /locus_tag="NOA48_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0788360.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(48205..49365)
                     /locus_tag="NOA48_000046"
     CDS             complement(48205..49365)
                     /locus_tag="NOA48_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0788361.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            49872..51572
                     /locus_tag="NOA48_000047"
     CDS             49872..51572
                     /locus_tag="NOA48_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788362.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(51674..52507)
                     /locus_tag="NOA48_000048"
     CDS             complement(51674..52507)
                     /locus_tag="NOA48_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI0788363.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(52811..54976)
                     /locus_tag="NOA48_000049"
     CDS             complement(52811..54976)
                     /locus_tag="NOA48_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0788364.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            55236..57530
                     /locus_tag="NOA48_000050"
     CDS             55236..57530
                     /locus_tag="NOA48_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0788365.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTTHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            57523..58188
                     /gene="pgmB"
                     /locus_tag="NOA48_000051"
     CDS             57523..58188
                     /gene="pgmB"
                     /locus_tag="NOA48_000051"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0788366.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            58181..59188
                     /locus_tag="NOA48_000052"
     CDS             58181..59188
                     /locus_tag="NOA48_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0788367.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            59210..60229
                     /locus_tag="NOA48_000053"
     CDS             59210..60229
                     /locus_tag="NOA48_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0788368.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOA48_000054"
     CDS             complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOA48_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI0788369.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(61986..63407)
                     /locus_tag="NOA48_000055"
     CDS             complement(61986..63407)
                     /locus_tag="NOA48_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0788370.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOA48_000056"
     CDS             complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOA48_000056"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0788371.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(65818..67074)
                     /locus_tag="NOA48_000057"
     CDS             complement(65818..67074)
                     /locus_tag="NOA48_000057"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCI0788372.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(67186..67391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            67654..68955
                     /locus_tag="NOA48_000058"
     CDS             67654..68955
                     /locus_tag="NOA48_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0788373.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(69024..69623)
                     /locus_tag="NOA48_000059"
     CDS             complement(69024..69623)
                     /locus_tag="NOA48_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0788374.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            69877..70758
                     /locus_tag="NOA48_000060"
     CDS             69877..70758
                     /locus_tag="NOA48_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788375.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            70771..72381
                     /locus_tag="NOA48_000061"
     CDS             70771..72381
                     /locus_tag="NOA48_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0788376.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(72458..73117)
                     /locus_tag="NOA48_000062"
     CDS             complement(72458..73117)
                     /locus_tag="NOA48_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0788377.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(73400..74065)
                     /locus_tag="NOA48_000063"
     CDS             complement(73400..74065)
                     /locus_tag="NOA48_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCI0788378.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        22144 a        14963 c        13229 g        23868 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcacac cctctcttct atcactttcc
     1741 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1801 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1861 tagtcttcgt tcttcttcta tcgtcgttac tggttctgct tttatttcat taaagtcgat
     1921 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1981 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     2041 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     2101 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     2161 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     2221 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     2281 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggctat
     2341 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2401 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2461 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2521 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2581 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2641 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2701 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2761 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2821 ataattagtt aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2881 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2941 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     3001 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     3061 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     3121 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     3181 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     3241 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3301 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3361 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3421 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3481 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3541 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3601 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3661 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3721 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3781 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3841 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3901 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3961 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     4021 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     4081 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     4141 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     4201 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     4261 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4321 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4381 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4441 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4501 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4561 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4621 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4681 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4741 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4801 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4861 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttagttg taaagattcc
     4921 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4981 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     5041 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     5101 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     5161 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     5221 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     5281 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5341 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5401 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5461 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5521 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5581 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5641 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5701 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5761 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5821 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5881 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5941 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     6001 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     6061 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     6121 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     6181 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     6241 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6301 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6361 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6421 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgtcttagaa
     6481 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6541 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6601 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6661 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6721 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6781 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6841 tctctcatta cgttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6901 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6961 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     7021 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     7081 caattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     7141 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     7201 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     7261 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7321 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7381 ttttaggaga tcacttaaca agcatcggcg atttttttgt tttgaaatct tcggttattg
     7441 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7501 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7561 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7621 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7681 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7741 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7801 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7861 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7921 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7981 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     8041 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     8101 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     8161 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     8221 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     8281 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8341 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8401 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8461 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8521 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8581 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8641 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8701 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8761 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8821 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8881 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8941 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     9001 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     9061 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     9121 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     9181 agccgatcca aacccttcgg ttcttttttg cctatcagtg caaaagcatt tcctgtgcaa
     9241 tttcacgtcc atccattgta tctggataaa atgttggcca attctccatt tctttcagca
     9301 atacttcttg actttcattt cctgcatata aatgaaaatg ttcggagtca gccggtgcaa
     9361 tcgtgtgatc actgaattga atatatctaa aagcgccact ttccttatct tctgcttcga
     9421 atagatacct tacgccacgg tttcctgcct cgtaggtcaa gatttctttc cctacataac
     9481 gataatttga acgtttcgtt gttccattct taaacgtaaa tgccatctct ttctcactga
     9541 tcttgattga agcaatatct gtttgatagc ccttcgtata atattcttta tattcttgtg
     9601 ctgtcttatc ctgattcaat ttttctttat attcaaaaac aggatcaaaa gtcccatctt
     9661 ctacatacgt atctactgtt tgccaagttc ctgcccaatc tgaaagagag cgatcttgta
     9721 catcctcgtc ttcaaaataa ccgttgtaga cgctcttttc ttttttgggg gtcaaagtat
     9781 cttctagcgg gttttctgtc tctgtcgttt ttttcaacgc ttcgaggttt gcttccatga
     9841 tagaaagata gttttctcca ttttctattt gttcattcgt caatccttcc aaaggattca
     9901 atacttctaa agatacacct gcttcgtttg ctaacgttct ggcaatacta tctttggcgt
     9961 tttcttcaaa ataaatatag ttgattccat gttctttaac aaagtgtttc agttcagcaa
    10021 ttctcgccgc agacggttct tcactagaag aaagaccagc aatcgatact tgattcaatc
    10081 catattctaa cgctagatag ttgaatgcag catgttgcgt gacaaaagat ctttgttttg
    10141 cttgcttaaa ggtttcttga taaagctgat ggagtgcttg aagtttctcg gtataggctg
    10201 ctgcattttt tgtccatact tcctgttttt ctgggtaagc ttcaatcagc tgatcacgta
    10261 tgtttgctac ctgcttgatt gctaaacttg gagctagcca tacatgtggg tctagctcat
    10321 gtgtatggcc ttcttccccg tgttcatggt catgatcatg tccttcttca cttcccggaa
    10381 gtaaaagcat accttctgtc gcttttatcg tatggacatt gccttcttgt aatgtttttt
    10441 ggattgcggg gacccatgtt tccatgtttt catcattata aacaaagata tctgtatctt
    10501 ggatctttgc catgtcttta gcagaaggtt cataatcgtg ggaatcagtc cctgctggaa
    10561 tcaataactc tacttctcct tcatccccga cgattgcttt tgtaaaatca tacatgggat
    10621 aaaaggtcgt catcacgctc aatttttctt tactgtcctc ggctttccca cttgccccgc
    10681 aagcagttaa catacctgct aaaaccagca tggccaatat acctatcaat cgtttcattt
    10741 atgacactcc tcttctcatc ttctttcatt tgaatgttcc gattcgcttt tcgcaaaccg
    10801 taatagttac gttttagcaa caggatttaa tttatcatat ggttaaaaga actgtcaagc
    10861 gttttcttat tttaattgat gagaaagttt atatgaatga ttgacgatat ttttgcaatc
    10921 aacctctatc attttccttt tatacccgct tttgtctata atgaagttat agataaagga
    10981 ggaaaaagag tgaaaaaaga aacagataca acgaatcgtt tgatccgctt tttaggagga
    11041 aaaacctctt actatgtttt aggaatagtt atcttacttg cgctgatcat ttattttttc
    11101 catcagatct cgtttatatt caagcctgtc ggaatcatta tcgctactat cttgccccca
    11161 ttattgtttg cactgatctt gtattatctt ttggaaccag tcatcaaacg tttgagcaag
    11221 cacctttcga ggaacttgtc agtcattatc gtttatgtga ttattttatt tttattgggg
    11281 cttggaagca tatggcttat tccttttctt gaagaacagg caaagacatt gatcagtagt
    11341 ttgccagatt tgtttcaaga ttttcaagag agtctccgac aatttttgga gaaaacacct
    11401 tttgccgatt catttaatca atttttcgct tctattgacg acgtgacgtc tgatatagct
    11461 ggatttattg gaaattattg ggaaagtggc gcacaacgga tcagcaacat tttttcaact
    11521 gttacagcta tttttattac tttatttact ggtccaattg tcgctttttt ccttttgaga
    11581 gatcctcaaa aattttatca gtcagtttta gcgattgtcc caccagcatt tcgtacagat
    11641 tttaaaaatt tgacaaagat tgctaatcaa caattgggtt catttctaaa ggggcaaatc
    11701 attgcttcat ttatccttgg agcagtctac tgggtttgtt tcttactgat cggattagaa
    11761 tttgctagtg ttttagctat ttctgctggg ttgttatgta tcattccata tattgggccg
    11821 tttatcgcct tctttccagg tttgatcatt gcattccaag actctacttt tatggctgtc
    11881 aaatttgtca ttgtctggtt tgccgtacaa cttctccacg gtgacttggt gattcctcga
    11941 gtaatgggtg atcgtttaca gatccatccg attacgatct taatcgtttt acttgtcatg
    12001 ggtgatctaa tgggaattgt gggcgttatt tttggtattc ctatctatac gttagtcaaa
    12061 ttactcgtta cttttatttt ccgtaaattc aaacaacgct acaataaatt ttatggcgat
    12121 aaaggagagt atgaaaactc ttcattttct gaagaagatt attttaaata aaacacaaaa
    12181 cgtcgatctt acgagaatag ctcgtaggaa cgacgttttg tgtttttgtt ttaatttttc
    12241 agcaaagcaa ttgcctggta tggttttagc tccagacttt gatgaagaac agtatcggaa
    12301 taattatcga taagaatatt ggcttctgtg aatccttctg ggatggcgat ccttgtatct
    12361 ttatcataga aatttgttaa tacaagcagc tgctgtcctt caaattggcg aagaaagcca
    12421 taaacttccg gatgatttgc ttcataagca tgataatctc cttgtgcaac gattggatat
    12481 gtttttctca gccgaatcaa tttcttgtaa taggacaaaa tagaatcttc agaagatagt
    12541 tctttttcta cattaatctc ttctagcttg cctccaactt ttaaccaagg tttccctgta
    12601 gtaaatcctg cttgttctgt gtctgaccat tgcatgggtg ttcgagagtt atcgcgagat
    12661 tttgctttga tccgacgaaa cgcttctttt tctgtgaatc cttgttcaag gagtaactta
    12721 taagcattca aactttctac gtcaatatag tcggaaatcg atgaatagtc tgggtcgatc
    12781 atgccgattt cttctcccat ataaatatag ggcgtcccac ggttcaaatg gatcatggtt
    12841 gctagcatct ctgctccttg ttttcgatac tgatcgatag ctacaaatcg attgagcgca
    12901 cgtggctgat catgattatt aaaaaataga gcattccagc cgttaccctc actcatcttt
    12961 tctccccatg tatgaaatag tcgctttaat tctgcaaaat caaatggagg agtagaccat
    13021 ttattcccat tttcataatc gactttcaaa tgatggaaat taaagaccat tgataattct
    13081 tctctactag gttctgtata caagatacaa ttttcgatcg tcgtagagct catttcaccg
    13141 actgtgatga tagtggaatc cgtcccaaac gttgcttggt tcaattcttt tagatacgta
    13201 tgggtgattg gtttgtccgt atattcaggt ttgccatcat tttctttatt atttttcaat
    13261 tgttcgtctt taccgataac attgataaca tcgaaacgga atccttttac ccctttttcc
    13321 atccaaaaac gaacaacttt gaatagttcc tctcttactg cttggttccg ccagttcaag
    13381 tcagcttgtg tccgatcata taagtgcaaa taatatttcc ccgtatctcc aaatggcgac
    13441 caagcacttc caccaaattt tgatacccaa tccgttggct cttctcttaa aatgaagaag
    13501 tcctgataat gctggtcccc tgctagtgct tttttgaacc attcatgttc tgtcgaaacg
    13561 tgattcagca ccatatcgag catgatttct atccggtatt tctttgcttc ggctattagc
    13621 tgttcgaatt cctccatcgt accaaagata ggatcgatgg ctgtgtaatc agagatatca
    13681 taaccgttgt ctttttgagg gcttggataa atagggttta gccaaatcat gtcgatgcct
    13741 agatcattca gatacgggag tttttctttg attcctttta aatctccaat tccatcacca
    13801 ttactgtctt tgtaagattt gggatagatt tggtaaatga ctttgtcttt aaatgtcatg
    13861 gatatttacc tccattcaac tgatttatta cctaccacaa cttatatata caagttatca
    13921 tttattatta taactgaacc gaaagcgttt gtaaaattta tctttataca ttctaagagg
    13981 tctgttgccc aataaaaaac aagagatcag acatgtattt gtctatcctc ttgtttaaaa
    14041 tagcaaaata ttcttgtttc ttctataaat ggtgttcaaa agcttttatc tacggcaatc
    14101 agtcttctca aatgtaaaac atgaggagct aattttattt gagtattctt tttgctcgat
    14161 gcaggacggc ttttttacaa cctctgattc atggtgttca atcagctgtc cttcggtatt
    14221 agctcaaaaa acggcaaaat atgaaaaact attttgccgt ttgtttctct aatactcagg
    14281 tcaaaccgct gatttcacaa cctctgtttt tattcattcg atttcaacgc atcaatcata
    14341 tcgatatgct ttaatttgaa atgggtaaca atcatcacaa taaccgtaaa tacgatagtt
    14401 aatcctgctg ataagacata agcccaccat gtgatcacta atggaaagat gacattctcc
    14461 atagacgctt gttgcaagat gaagtcagtc aatatatatc ctacaccaaa tcctccgatg
    14521 attcctaaaa gagtaaagat gatattttct cgaacaatgt acatcgtgac ttctttatca
    14581 aaaaatccaa ggacttttat tgtagataat tcgcgtacac gctcggaaat attgatatta
    14641 gttagattat acaagacgat aaaagccagc agtcctgata atacgacaaa gattaagaca
    14701 accgagtcta agttcgccat tgattcttct tgcgtttcga tttgtttgga catgaaagac
    14761 gtatttgtca cagcgtctgt ggcaagcagt ttctcggaaa gcatttcttc ttcttttgtt
    14821 gtcatcttat ctgtacgcag caaaaatgca ttatccatca tcgattgatc agtaactgaa
    14881 gcataatatt caggggacat ataaataaag ctacctagat agtttttcac gatttctttt
    14941 acttcgactt tccattcttt ttgatcttca tcataaagcg aaatatgatc tcctgtagat
    15001 aagtcaaata gttctgctac tttttgcgta atagcgattc ctgttttagg caaggagcgt
    15061 gggttctctt caagatcagt taaatggata aaacgatcca aatcagctgt tttacttggt
    15121 acgatcactg tcagactttg cgaagcatgt cctttttttc tcaattctac ggtttgagta
    15181 tgaatagcta ggatctcatt tactttttct tgcttctgca gcatatccgc tgctttttga
    15241 cgactatctt ccgtggatga atccaatgta acgattgctt gatagtcaat gatcggtcca
    15301 aattgtttgg ctgaaacaga acttagagaa tctttcaatc ccacgcctgc aaccatcagc
    15361 ccggcacatc cagcaattcc gataatcgcc ataagcattc ttgacttata tcggaagaga
    15421 tttcggtaac tgattttttg attaaagcta aggcgtgacc acagcggagt gatgtattca
    15481 agaaaaatgc gtttccctgg cttcggtgct ttcggttgaa gcaatgcagc aggccgttct
    15541 cttaaatctt tgaataaaac gatcattgca gcgccaaatg cggcaatgaa gaatgcggca
    15601 gctgcttgta aaatcggcgg ccagtcataa aaaataagcg cactcccaat atcataccgc
    15661 tcgttagaca gctcaaaaat gatccttggc aaaagattcg ttcctaatat cgttcctaaa
    15721 acaataccta tccctgaggc tagacttgca tagattgcat atttttttgc gatttcaact
    15781 ttcgtataac ctaacgcctt taatgtcccg atttccctgc ggttttcttc taccatacgt
    15841 gtcattgtcg taaaggtgat caatgcggca ataaagaaaa agaaaacagg aaaaacattg
    15901 gcaatcgcag cgatacgatc agacagatca ccaaattctt gaaaaccgac attttctgaa
    15961 cgttcattgt ataggtatga tggtttagtt aaattttcaa ttttttctgc atttcgattc
    16021 aattcttcct ctgcagaggc cagttcacgt tctttctcaa ctaattgcct ttcttgttca
    16081 gcaagttgag cttcttgttg agataatgtt tgaacagcga ttgttcgttg cgcttcagga
    16141 agctgctgga tagttgctga ctgttgcgct aactgttttt tagcatcttc taaccgtgtt
    16201 cttgcttgcg ttgtttgtgc tttgccatcc gctatttttt gctgtgccgg ttctaattct
    16261 tcgttggccg attttttcag ctcttctaag cgttcttcgg gtcgatcttg taaatacttt
    16321 tctgcctttt cttgattttg ctccatttta tctttgtaag ctttgctgta cgtattcaaa
    16381 ttctttacgt ttgtaaaatc aagatataag acagaataaa tatctgtttt aaaaacggat
    16441 tcaggtaaat agacaaaata atcgacgcta ccatttccga cgttcgcgta tcctctctcc
    16501 aaattgttga tgaacaatgg agaacggaca aagcccgtga tggtatactc tttttctttc
    16561 aattcatctg aatcaatctg ataaatatca ccgattttat acccttcatc ttccgctttt
    16621 tcatccaata caagctggtt tggtttttcc gggagttttc catcagttaa ttgtagcttg
    16681 ttctgcttgt tatttttgtt ataagaaaat atttgaatca cttcgttttt gccagtattg
    16741 gaataataga tctgttttcc tgtttctact tttgcatctg ggatcttttc tgcttgagca
    16801 atatcttttt gtgtcaagcc accagtagaa acgatttgca aatcagaaag tcctgctgta
    16861 ccaacatagt gatccatcgt tttttgcatg acaggtccag cagttttgac acctacaaat
    16921 aaaagtgttc ctagcatgac aataaggatg attgcaatga atcgtccttt agattgccga
    16981 atttcgcgaa aacctgcttt aagatatgtt cttgttttca taaaatcccc ctaccataca
    17041 atctcatcaa tggatgaagg atgatcattt aattcaacag accttacttt agcatcatta
    17101 atgtgaatga ctctatcagc gatgggcgct aaagcagaat tatgtgtaat gatcaaaacg
    17161 gtattgccgt gttgtctgct agcgttttgc aataatttca atacttgctt gcccgtttca
    17221 aaatccagcg cgcctgtcgg ttcatcacat aaaagaagtt tgggattttt agctagtgca
    17281 cgagcaattg aaaccctctg ctgttcgcct cctgataatt gggacggaaa gttattcaat
    17341 cgatgagcta ggcccacttg cctcaatacc tctacaggat caagcgcatc aggagaaact
    17401 tccgttgcca attccacatt ttcttttgct gttagattag gaacgagatt gtagaattgg
    17461 aaaacgaacc ctacatctgt tcgtcggtaa gcagtaagct gtttatctga aaattgcgca
    17521 atatctgtgt catcaataat gatctgacct tcatcaggtg tatccatccc acctaaaata
    17581 ttaagaatcg ttgactttcc tgctccactt ggaccaagta taatcactaa ttcgcctttt
    17641 tcaattgaaa aagaaatatc gtcatttgct gtaatggtcg tttctcccat tttgtatcgt
    17701 ttgtattcat tttttacttc gacatacttc actctgattc ctccattttc acgatatttc
    17761 tcgctatatc tatgcatcga atgcgttttc tcacacttat ttattttacc actgaatttc
    17821 tctagactaa agaaaggaat cctttaattt agttgacaaa taaacgattt atgatttact
    17881 tacataaaaa acattgttat ttgaaagaag gaacatcatg aatgatttaa aggaaaatat
    17941 gatttttgat ttatcaaaaa ctgcttttgt cgcgatcgac atgcaaaaag agatcgtaaa
    18001 taacggtaca ctctctccac acactgcagc atctattctg acaaacaatg atttgttagt
    18061 aagaacattg aaacgtaccg ctgccttgaa agttttagtg aacgtagaca tctccacttt
    18121 cccttatttg agtcaacaaa ctgatatggg tggaatgact gcttctgtac ctccagaatt
    18181 cactgattta cttttgaagg attctttgaa agatacagat aatatgttga ctatcacaaa
    18241 atacaatcca agtgcttttt ttggtacttc tcttgatctt caacttcgcc ggcgtggaat
    18301 cgaaactatc attttaagcg gtgtagcgac aacaaacggt gtatatgcta ctgcattaga
    18361 tgcctttcaa cacgggtacc atatcgtgct tgctgaagat gcttgcagtg atcgtgacaa
    18421 agaatcccat caattgttca taaaaaagat atttccgaaa actgcacgag tacgctcaac
    18481 gaaacaaata atcgaagcta tccaacaaag caaataagta ctggcacacg tgattttcat
    18541 ttacttcttt ttgatttcat gggaaaataa ccacaggatt tagataggag tatgaacatg
    18601 gtgaaaaaaa agatcacaat caaagaagtc gctaaacttt ccggcgtttc aatcacaact
    18661 gtctccttga tattaaatgg aaatacggag aaattcagtc cgaaaactgt tcagaaagtt
    18721 ttagctgcca aagaagaatt aggctatcag cctgactatt ttgctagaca aatgattacc
    18781 aaggaaacga aaacaattgg tgtactcgtt cctgatatca cgaatccatt cttcagtaca
    18841 ctgatgcgag gaattgagga tatcttgtat aagcagaatt tcgtcacgat attatgtaat
    18901 gctgattctg atcatcaaaa agaaatcgaa tatctagccg agctcacacg tcgaggtgtg
    18961 gatggattca ttatcgcgac ttctgctgtc tctacagatg caatcaacga aaatttgaaa
    19021 aaacaaggcc ggcccttcat tgttttggat cagaaaaaat ctgaaggatt tagtgatgcc
    19081 gtacgaacag acgattttcg cggtggttac ctagcgggca tgcacttgct tagtctagga
    19141 catcaaacga tcgcccttgt ctatcctgaa aatccaccgg aaaatgtcca cgctcggatt
    19201 gaggggttta aatctgctct tgatgtttac caaatccctc acgaccaact gatcctctta
    19261 cctacacagt tctcaaaaca aggtggctac cagatcacag cagaacttct tgattctgct
    19321 gcaactggtg tgtttgcttt aaatgatgaa ttagcttttg gattatatcg cggattagag
    19381 gaagctggaa aaagcatccc tgaagactac agcattattg gctatgataa tatagatatg
    19441 tgcgagtata tcaagccgaa actgacaacg atcgcacaac caatcttcga attgggacaa
    19501 acatctgcca agttattgtt agatcggatc caattcccag aaaaagaatg ggaagaaaaa
    19561 agattacctg tacgattaga aaaaagattt tcaactgcac ccttgaaata gctttcaagg
    19621 tgtgctatat ttttatcgaa ctattaaaac gttttactaa aacgttttaa aaaataattt
    19681 tcccatcaaa ataaatgaga tagttggagg tttgtaaaat gaacacggtt acagtaattg
    19741 gaagtattaa tatggacact acccttcgtt taaccaacat gcccaagcca ggcgaaacga
    19801 tgcatgcgca tgagattttt cacgctggcg gaggtaaagg tgccaaccaa gcagtggcag
    19861 ccaaacgttc aggcgcacgg acatctttta ttggaggcgt tggggctgac agcgaaggac
    19921 aacagttatt agatctactg acaaaagaaa acatcgatac atctgggata gctgaaatcc
    19981 aaggcgccac aaccggacaa gcaatgatta tggtagacgc agcaggagaa aatagtatct
    20041 tgatccatgc aggggcaaat aatgctttcc atgaacaaga agtcctaaaa aacaagcaac
    20101 tgattacaaa cagtgacttt attattgctc agtttgaaag tagcttagat gcgacgatcc
    20161 tagctttttc tattgcaaaa gacgcaggaa aaacaacgat cctgaatcct gcaccagctc
    20221 gtgaaacgat tcctactgaa ctacttgaaa agacagatat cattatacca aatgaaacag
    20281 aaacagaaat cattacagga atcagagtga cagatcataa cagtttggtc gcagcagccg
    20341 aaaaactcca tgaattaggt attggaacag taatcattac actaggcagt gccggcgctt
    20401 tctatcatac agaaaaagaa cacggtatcg tccctgcttt taaagtggat gcccttgaca
    20461 caacagccgc aggtgataca tttattggcg cattaagcag cacacttcag ccagacctta
    20521 gtaacttgaa agaagcgatc ctttatggaa atctagcctc ttctgttgct gtgcagtctt
    20581 atggtgcgca accttctatc ccttaccgcg aagctttaga acaatcagca gtctaaaatt
    20641 aacaatgaga ggaagaaaca aacatgaaaa aaggaaaagt aatcaattca gatatttcac
    20701 gagtaatcgc acaaatgggg cactttgata aattaagtat cggggatgca ggcatgcctg
    20761 tcccctttgg tactgaaaaa atagatttgg ctgtctcaaa cggtcttcca agttttttat
    20821 ctgttttaga aaacgtttta gaagaacttg aggtacaatc gattgaattg gcggaagaaa
    20881 taaagacaat gaacccggaa atattggaaa aaatcaaatt attgttacca gatacaccga
    20941 ttagctttat cccacatgaa gaaatgaaaa aagagttgaa taactgtcat gcatttattc
    21001 gtacaggcga aatgacacct tacgccaata ttatattagt gagtggagtg gtcttctaat
    21061 ggaaacgaca atgaatcctg aacagatggt actgtccgag cagattcata tgctgattga
    21121 acagttggga ggaaaagaca atattgattc tgtccttcca tgtgcgactc ggcttcgtat
    21181 caaattgaaa aaacagccag tagccaatgc agaaaaatta aaacagcaaa tcccttccat
    21241 taagtatttc attttactcg atagatatgc agaaataatc atggatcagg gattggctcc
    21301 tgcttacaag gaattgacgc gtcaaatcga tcattcagct ccgaaagaaa agctaaatcc
    21361 gatcgaaaaa ctatttggtt tgatatcgga aatctttacg ccgatcattc cgctgtttgc
    21421 cggttctggt atattaaaag gtctggttgt tttagcgact acgattggct ggcttagtga
    21481 aacaagcgga acttatcata ttttgtctgc tgcgtcgaat gccgtctttt attttctgcc
    21541 aatctttctt gctttttctg ctgccaaaac gtttaaagtg aatggatata ttgcggctgt
    21601 cattgctgca gcactgattg aaccgaatct gacctcttta ctttcagaca gtggcaaagc
    21661 agctactgat tttctgggga ttcctgtagt actgatgcag tatacgtcta ctgtcatgcc
    21721 ggcgatttta ggtattttct tttattcttt tgttgaaaaa ttcctcaaaa aatatattcg
    21781 cgaaaatatg caattagtat ttgtaccttt actttcatta gttatcacgg ttcctttgac
    21841 gttaatggta ttcgggcctg cgggtgttta ccttggcgaa ggtttagctg ccgcaattac
    21901 ttggatgatg gatattaacg gaccgatcag tggcgcaatc atcgctggtg gttggaatat
    21961 tttggtaata tttggtatcc aatgggctgt aaaccctgtc atgatcagta atatctctgc
    22021 ttatgggttc gaccgaatcg ttccgttgac aggagcagcc aattttggaa tggctggtgc
    22081 agctttaggt gtatttctgc gaagtaaacg ttcaaaaacc cgttcgatct ccggttctgc
    22141 ttttgcttcg attttacttg cgggagtgac cgaaccaact gtttacggaa ttgcgatccc
    22201 attgaaaaaa ccatttgttg ctgcttgcat tggtgcagct gctggtggag ctgtaatggg
    22261 atttgcccaa gtgaaagcga tcgcttttgt atttggtagt ctgaccacat tgcctgcatt
    22321 catttccggt acttttttct ggtacttagc aggactggct gttagtctag tcgtagcaat
    22381 gatcactact ctcgttagcg ggtttgatga agacctaatg tcttatgaat agttaatgaa
    22441 aaagactgaa gtatgagatg tttatcacat atttcagtct ttttcttttt aggatcatta
    22501 tttttataaa tttttgtgat actttccaaa ctttggtata atttacatat gcataaccat
    22561 ttttatcccc acttgtttat ccccaaacaa aggtggtcta tgcaataaaa tgaacgtcaa
    22621 agaaaaacga atgaatgctc gttgcttatt tacaaattgt tttatttaga atacacagac
    22681 agatttatga aaagaaaaag cttttcgaca cgattatctg ttccaaaaaa tgtctaatga
    22741 atgctgaata agacagaaaa tcaatgaaag gaaaaggact agtttattat gaaaaataaa
    22801 aaaacgatac gtttgctagc tgctacttgg ctgattgctc cgtctgtttt gtcgaccaat
    22861 accgtatttg ccgtagataa tcaaatagct gatcaaacag tcacaacaga tacgactaca
    22921 tccagctcag ctactagtga aacaacggat tcttttacag aagacccaac tggaacaact
    22981 aactcaacaa caggatcgac cgagccaact gaaattgatc cggctgatcc atcagaaaat
    23041 gaaaagccag ccgagacata ttcccttaca attgctcctt ctttgattgg taagatccaa
    23101 ctgactgctt cgacagcgga ttcccctgaa cagcaacctt tggatattac ggaaagtgga
    23161 acggtagaag gtttattagc ggaaacgaag gtaacttaca ctattacgcc agctgaaggt
    23221 gaacaaattg cttcagtcgc tgttaatggt gccaaagaag taaattatga tgcaaagacc
    23281 tttacagtag gtacgaacaa tttatctatt actgcagaat ttaaagctgg accggatact
    23341 tcaacagaga aaccaactga tcctagtgaa gaagtcccta gtacaccaga tccggaaacg
    23401 ccaaacaaac cagatgtggg taataacaac aataataatg gttcaaataa ttcaaacaat
    23461 aataacaata attcgaacag cgggaattct tcgaatcaaa caaacccatc tggatcgaat
    23521 aacaatggaa atactcagag agaaccaaac catccaaaca atggttcatc gaatggcgga
    23581 acgaacaatg cttcatctcg tccaaataca gcaaatcaaa gcggtataga gaatccatct
    23641 tctgcttctt ctgattttgt tgtaaaatca ccaattgatg ctgtattgcc tacaaataca
    23701 acgaatgtcc aacaagcaat cgttcgagaa gcattcaagc atcttggaaa accatatgta
    23761 tggggagcaa aaggtccaaa tacttttgac tgttctggtt tgacttatta cgtatatatg
    23821 aaagcaaccg gtcattatat cggtggctgg acaggcgaac agcaatatgc aggtacgcag
    23881 attccagtaa gtcaggccca acctggcgac ctcgtcttct ggggaccttc ttccggtgtt
    23941 actcaccatg taggtatcta tattgggaac ggacaattta tccatgcgcc tcaaccagga
    24001 gataaagttc gagtaacttc tatttcagat ttcacgcctg attttgctgt ccgagtaaac
    24061 ttagcaggtt tacctgctgc ttcaggttcg ctgacaggcg gctcatctat tttagatgga
    24121 ttagatggct cgttccattt cagtcaaaac caaacaactg atcagttctt gaaaaagatt
    24181 gcagatgatg cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt catgatggct
    24241 caagctatcc ttgaaagtgg atctggaaac agcttattat caagcgaacc aaatcataac
    24301 ctttttggta tcaaaggatc atataaagga agcagcgtga ccttcaatac acttgaacaa
    24361 gatagttccg gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc ttcttacaag
    24421 gaaagtttgg aagactatgc cgacttgatc aaaaatggac tgactggcaa tcctgatttc
    24481 tacaaaccaa cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa atatttggaa
    24541 ggacgttatg ctacagatcg ccaatattca caaaaattga acgcgatcat cgaagcgtac
    24601 gacctgacaa aatatgatga accgaaaaaa gaagcagcaa caactgaaga agcaaacgct
    24661 gaaatcctca atatgtctaa gcgattcgat gtgccaatca aatggacaac agatggcgtg
    24721 ccaatcacag gattagaatt ttcaacgata aaacgcgtca acaacgcttc ttccatcttc
    24781 cgtgtcgctt caatctggga tttgtggaac aattttacgg caagacagat accagaaaca
    24841 actactcgta cagttaaagc tgcaactgtt cctgtactaa ccttgttaag tttagacaaa
    24901 tcattctggc ttgatctgcc tttaaagaaa tagaataaat taaaaagggg atgtgacact
    24961 gtcacactcc ctttttaatt tattctattt ctttatattt attttgtatt ccgttacaaa
    25021 ctcgcgtact tggttaggtt ccagagtgac atctccaaaa ctttcaagtc gctccgctcc
    25081 tggcagttct tgagtctcaa atgtgatacc gccatgattt actaatttat tcccgcgcat
    25141 ttccggtcca tcttctccaa aatttgctgt aaaaatcacg attcctgaag catctgtttt
    25201 tacttggatc gatacttttt catctgggct tgtcaattcc gcagcattta gtaaaccaga
    25261 ttgttttttc aacaaaaatg gatgatcgat gccgcccact atcattgatt ggcgaaaatc
    25321 actggcaaag acctcaccta attttttagg acgttggaag tcaaatgctg tgccacttac
    25381 tgaaactact tctcctgtag gcgttgtatc tttattgagc gtagcaaata atcggctatt
    25441 caaccaaagt atatgttcgt cgattgactg tgctggatca ccggttaaat tgaaatagac
    25501 atgatttgta ggattgaata ctgttttgcg gtcactgatc ccttggaccg tcactcgcca
    25561 tgtatcatcg ttcgtcagcg tataccgtac ttctacatct aaagttccag gaaatccgtt
    25621 ttccatatct gggctagtct gatagaaaat gaccgatgct tcgttttcac cattgatgac
    25681 tgtataatgc cactgcttgg cttcaaagct aggtgcacca ccatgtaaac aatgaccagt
    25741 gtccgggtct gtttttactt cgaacgtttc atcatctaat ttgaatgtgc cattcgtaat
    25801 ccgtccagcc atacgtccga ttgaagcacc gatataaggg tctttttcta gatattcttt
    25861 tgcttcatca aaacctaaga tcaactctcg tttttcatta tcgattattg tttgaaaatg
    25921 aacaacccgt gccccaagat cactgacaga caaagatgtc ccattttgat tcgtgatcgt
    25981 aatcaagtga tagttttcgc caaaattttg ttcattgatt tccatgttcc ttgcaccctc
    26041 ttttctttca tttgcactga ttccagtata catggaaacc gttttcttaa cagcttattc
    26101 cgtgagtaac gagaaaaaat ttactatatt ctaataaaag accgtgaaaa aaaggttgtg
    26161 acaaaaatat tgtcacaacc tctttttccg aacaaacggt gttcaaaagc ttgcatctgc
    26221 ggtaataagc ccaaccaaac gaaaaatatg aggagctatt tttgcttggc tgttcttatt
    26281 acttgatgca ggacagcttt ttcacaatct ctttttcaat acgattccag tatataacca
    26341 tgtcgtcagt acatagtaga tgaaatacaa tacgaagaat atcgtaaacg gaacccaaat
    26401 atctttgtat ggattttgca tgaatagacc aaacatttgt aatccgaata agacatggac
    26461 tacacctaag attcctggtg ctaagaataa cacgcctact tctctacgga tcgattgttt
    26521 aagcaacccg cgtcgtgttc ctatcttttc aagcatttca taacgagcaa tgtcactctt
    26581 gcttcctgac aagatcttga acatcaaaca gctagcaagc atggtcaaga aagctaaacc
    26641 taggaagaat cccataaatt caaaaccaga gaatagacca ttatacactt catacatttc
    26701 atatttctgg ttgctgtact ctactttttg caaagatgga ttgttcattt tattttgagc
    26761 aacaagtgtt tcgattggtt tcaggtttgc ttggaagtct tttacctgaa ctagctgtaa
    26821 agtggattgt ggcaagttca gttgatcaaa ttctgattga ctgactacct tgatttcttt
    26881 ttcttgctgt tccggcaatt catagcttcg aagttcctct tgtacagtca gttcattcat
    26941 ttttttagca ggaacttttt ctttcgtgat cttcggcggt gttccatctt catgttttat
    27001 catgatcaat ggttgagccg caaattcact tgcattatag taaatcgttc ccgcatcttc
    27061 tttttgagta taagaagcag aaagtgttgg tgaaagttct ttgatttttt gctgatcttc
    27121 tgcccgagga ttattcatca ctagatcata tccagaattg ttttctgtca agtctgcaat
    27181 ttcattttta aaacctaatc ctaccgtcaa agcgcccagt gccaaggcaa acagcatagc
    27241 gaccattgag agcatttgtg tatattcacg aatacgaaag tttaactgtg acaatgtgaa
    27301 attgttcaat tttttcaatg aaatctgttc tgatttcttt agtaatgata aaaagaaaat
    27361 gatcacagaa tggaaaatga aataagttcc taatacgatc gtaactaagg ctacccctat
    27421 accaaagact tgataggtcc ccacgtgttt catcatatag taaccgcagc ctagaaaagc
    27481 aattcccagt actacttcaa ggaaaaacaa gaatttatgc tgcttgattc ttgttggtgt
    27541 ctgatccgca cgaatcaatg ctaaaatcgg ttttttgaca atcgaaaaag cattgacaac
    27601 agcagctaat aaaaacaaaa cagcaaaaaa caaaacagtg atcaacaacc cgtgaatact
    27661 aaaaggtgta aaatgcgaaa tattgagatc taactgatcc actaataatc ggtggacgat
    27721 acttgtcaat cctacaccga cagctgaacc cactaaagta gctgcgatcc ctactaagaa
    27781 tgtttcagaa aaaatcatct gtgcgatttt tctgcctttt gctcccagca tcataaacat
    27841 tgcatagtct ttttgccgca tcgtcatcaa aaaggaattt gcatataaaa tataaacgaa
    27901 tgtgatgatc cctagtaaaa cagaaccgaa tcggaaaatg ataactgtag ccgcaacgat
    27961 cgtattactt ttcaaaaaag cttcgttgct tgccattgat tcaaacatgt aaaaaatagc
    28021 agatgccata actaatcctg agaataacac caagtagtct cttaaacggc tcttgatccc
    28081 agtaagtgat aatttccaaa gcatagtcaa tctcccccta ctgttccaag tttccaagaa
    28141 tagatagtat ttctcgatag aaggaatcac ggctttgatc tccacgtttc acttcttgat
    28201 ggataccgcc atccttgatg aataaaatac gttggcaata acttgcagaa aacggatcat
    28261 gcgtcacaag aagaatcgat acatgatctt ttgtattcaa ttcgtccatc gtatctaaaa
    28321 gatcccgggc acttttggaa tccagcgcac ctgtaggctc atcccctaat agaatcgttg
    28381 gttgtgtgat caatgcacgt gcggcggcga cccgttgttt ttgtccaccg gaaatctcag
    28441 aaggatagct ttccaaaata tgagagatgg ataaacgttc tgcaattttt tggacacgtt
    28501 gcttgatttc ttttggtctg acgccttgta aagaaagagg aacagcgata ttttcttgtg
    28561 ctgtcaagct ttctaataaa ttgaaatctt ggaaaataaa gccaatctca ttcgcacgaa
    28621 aatctgctag ttgatttcct tttaatgtgg tcacatcttt ttgattgatt cggatatgcc
    28681 catctgttgg tttatctaat gtggataaaa tattcaaaag tgtcgactta ccagaaccag
    28741 aagcgcccat gatcccaata aattcgcctt tttctacatc gaagctgatg ccgcttaatg
    28801 cttgcgtctt tttctcattg ttttttccgt atacttttgt tacattctgt acttcgacta
    28861 ttttgttcat ttctttccct accctttaat tagtttttcc agtgctgttt tcggcacgtc
    28921 ttttttttcg acttcttcat acgaagtgac acctttattt ttgttccagg tgatttttaa
    28981 atatgctcct ttacgaagcg gtcgagtcaa ttgtcccttg aagtccagtt ctttttcctt
    29041 accctctttc gtatagccag gcaggatata tctatagttg actgtttctt gtccagagtc
    29101 tgattttgaa actgtttttg taccatctgt cgtaatttgt acatagtatt cttctccacc
    29161 cataactacg taatctgcga ttttcacccc tgcaagtacc acaacgatga aaacaagtag
    29221 accgatcaga agttttttca ctttttcccc ttctctctta ctttatatac tgattataga
    29281 aaaaagcgaa caattctgcc ttcgaatcaa ctatcattct tctttcaatt ttgtcatttt
    29341 ctttaaaaca actaaaaaaa gagttcaaga caataatccg tcctaaactc cttcttccta
    29401 tcttacaaaa agtatgtcac ttacggtctt tcatgtcgcc tgtattgata acaggttgcg
    29461 ttcctttgtc tgtaatgatt gagacaagta aattattgat caattggact ttccgatcat
    29521 cggtgaaatt gatttcttgt ccatcttcga tttgctctaa ggccatttga gtgattgtga
    29581 cagctccttc aacaatggtt tgtcgagcag acaaaatggc ttttgcttgt tgacgttgga
    29641 gcatggcact agcgatttct gttgcatagg ctaaatggtt caagcgtgtt tcgattactt
    29701 cgacacctgc tactgctaaa cgctcttgca gctctttttg caactcgtca gacactgccg
    29761 tcgtgtttcc tcgaagcgtc aaatcattct cattgaatgt atcatacggg tattggctag
    29821 cgatatgccg aatggctgtc tcactttgga tttctacaaa atcttgataa tacgctacat
    29881 cgaataatgc ctttgctgta tcaacgactt taaagactac tactgctgag atttcgatgg
    29941 ggtttccatc caaatcattg acttttaaaa cagaactatt gaaattccga actttcaacg
    30001 aaacagtcat tttttgtgcc aaaggtatcg taaggaaaaa gccattttct cgaatcgtac
    30061 ctaaatattg tccaaaaaac aaaattactt ttgcttgatt aggactgact acagttgccg
    30121 aacttaacaa caataacgtg atcaaccaaa gaaaaatact taaaaaaagt gcccaaactt
    30181 tcgcttgcca catacctaaa tagaagaaaa acaatccaac taaagctaat acgaccaatc
    30241 cgacaatccc tgcataacca ttgatataaa atgctctttt ttctctcatg ctacttcctg
    30301 cgctccttta tccttcaata aatatctaat gttacttttt taattttttt ttcgaatacg
    30361 cgccattaca ccttctagtt ctaactcttt gtcttcagtg atgtaccaac cgcttgcctg
    30421 tgtccctccg gctgcctgcg gtaaataatc caattttgtt cgaacccagt gcttttcttc
    30481 tgtaaaatag tcttctacca agacctctag atccatccct gctgaaagag gcaaatcttc
    30541 ccgaacagat ttaaagataa atcgttcctt cttcccatca tacttcaata ttcctgtatc
    30601 gataatcggt aaagaataat aatccagctc tttcttcacc gtcaataaat gtttgaaaac
    30661 ttcatggtac acttgctcta attggcgacc ttctgaattg ttcgggtaat taaccatcac
    30721 tttttctttg tctggatcat agaaggtttg gcttagttga gtgatataag tatgtaatct
    30781 ttccatttct gtttttaact tttctctttg accttcttct accttcatat actctttcac
    30841 cctgttttct ttttagatat tttctttctt attttactat agttatgtgc gttaagcgat
    30901 gaaaaacagc aaagattgga aggatctttg ctgttttttc ttaaaatatc cagttgagta
    30961 caggatcaat ctgtttcatt gtcctcttga tccgtcgtaa tattgatcga tgtgtcttta
    31021 gcagtgatct ttagcttttt ctgtccttgt tctaacaaag tatttgttat tggctggtag
    31081 tctttttcaa tataagattc accagacgtt tggatagtat agccactgtt ttccatctca
    31141 tgcaaagata aattgccacc gtttaggatg acttttcctt ctttgctgat caaactgtct
    31201 tctagatgga agttgctgtt ttcacctgtg acgatcaagt tatccacatt ggcctcatct
    31261 aatcgaagtg agcctaattc atctttcgca gttattgttc ctcctgtaaa ttcattgaac
    31321 gatacccagc catcatgtgt cttagtattc acttttttga ttgatacttc gttgatatca
    31381 attgcactat tattcccttc gattgtcaat tcagataatt catgatctgc agggacaaca
    31441 atagtgattt gtgcacttgt gtcttctaaa ctaatgattg cacctgttga ttttttgact
    31501 gcattcacag tcaacacgcc atttttctcc tttatttctg gcttttctgt cttatcataa
    31561 gtcgttttta tctcaaaatc caatccgcgt atgaccgaaa ctgtttgatt ttctgcatgg
    31621 atgacgattt tgtttgcatc cttgattttt tttgtctcag taaccatatc gatcaaccga
    31681 ggaccattat cccaagtcag actcttttga gcgcctaatg tataagttgc acctgctagg
    31741 aggccaccag taagcatcag accaataccg gtaatcaaaa aatgtttcaa tctcaattta
    31801 tgtgtcctcc ttcaaacgcc cgctgaatgc agatctcttt ttgtaataaa acgtcgtccc
    31861 atccatttaa caaagttcat catgacataa aaaagccctt ttgttccttt cagcaacagt
    31921 ggcgaaataa atactgcgct tcctgtggcg aacagaccga caccgataaa gaataatcca
    31981 ctcagaatcg attgtccaaa cacactgatt cctgagatga tcatgaatag gccaacacct
    32041 aagatactga tacataaaac atagatacta aaaatgagcg ctagtaaagc aaccaatagt
    32101 cccccaataa ccaatataaa ccccagtgct agtggaatga ggacaggaga agcaaataaa
    32161 ccgataatga ttaaccaaat caggcgaatt tgtctttttg gatttttcac taactcgttt
    32221 tctgcttgtt cttcttctga aaagtaactg atttttaatt ttaaggcaaa ctgctttggt
    32281 gtaccatatt catcaatgat ctgatctaat gtttttccag aatctaaaaa atattcctca
    32341 taatactgga tcaaatcaaa acgatcgtct tcaggaattt cttgaagatg atccacaact
    32401 tcattcaaat attcattcat ttgtgctctc ctccaataac cggtctaaag aatctcgaaa
    32461 aacaatccat tcatcaataa tttcttctaa atgacgactt cccattggtg tcaacgagta
    32521 atatcgacgg tttctgcctt caaaaggttc atcataggtc tcaagatatc cttctttttt
    32581 caatcttctc aaaaccggat atagtgtaga ttcactgaca gagagacttt cttgtacgat
    32641 ttttgttaag gcatacccat acatatcttc cttgcttaat gctgctagca cagtaccatc
    32701 aagaagaaca gttggaatct ggatgtgcat tacgtcacct tctattctca agtgtaatat
    32761 tttatttcaa tctatattat acaacatata atatagtttc aaaatcagtt tgtcaaatac
    32821 aaaaaaactg actaaaagat ttgatccttt ttagtcagca aaaaatggct tctctttgat
    32881 ttttattata acagtggcat aatccaattt gtccacatcc agctcagtgg catgataacg
    32941 atcattgcag gtatcatgtc agctactggg aacattttca cgttgatcat tctaaaaccg
    33001 gtagcgacca tcaagaatcc gccgcaagct ttaaaatcta agatcatgtc tggtgtagtc
    33061 aatggataaa taaattttgc caataagaac aaaatataaa aaataatgaa ttggggaatt
    33121 gctatcacag aaacgacata ccctaaatta cacgcaaaaa tagctgctgt gaaaaaatca
    33181 aggacagatt tagaaatcaa aatcgtactg tctcctgtca tcccagaatc taaacttcca
    33241 tagatccccg taccacttgc acaaaataga acaatgaccg tcactaatgt gctgataaat
    33301 tcatcgtggg tcataccaag cttttcacta gggaagattt tagaaatagg tacttgcatc
    33361 agcgcagccc ccttatttat cccattacct aaatgaacaa tcaaaccaat cgctgttcct
    33421 atcactaaag caaaaataac agccggcata tttttcatcg gcgcaatgga atagattccc
    33481 atccccatcg aacacacacc aaaaaccatc gtcagctgtg ctttaaaatg ttcacttaat
    33541 ttatttccta ctaatccgcc aattagtccg ccaaacaaaa cggaacctac attgatcaaa
    33601 actccagttg gcatcaaaaa actcctctct ttttctacga agcgaaaaaa atcagaaaaa
    33661 tttctgtaat tattgctttc gctgcaagaa agattgtaac agacagagaa gattacacca
    33721 attcattttt tgtgttaaag tattctttat tggaataagt aggaggaata tgatggatat
    33781 ccataaattc gaagtttttc ttgatttagc cgaaacaatg aatttcacca aaactgctga
    33841 tcgacaattc accacccaag gaaatatttc taaacagatt ctttcgttag aaacagaatt
    33901 agacgtcaaa ttattcgaac gcgcccatag aaaaatcgaa ttgaccgaag ctggaagctt
    33961 attgctccca tatgtaaaaa atgtcgtaga acaataccat gctatgcaag aagtgcttga
    34021 aacctatacg aaagacaaca atctttcatt aaatatctta acgataccga caatgatcaa
    34081 ttataaaggt ttttccaaaa tcaccgagtt tttgaaacgc catcctgaat ttacagtcca
    34141 gttgaaagaa gtggaaagtg tcgaattaac ttacaatgac gccaatgaac atagtgacac
    34201 gatccacttt gctagaagtt tccaggcccc accaagttcg attgagtggt tgcctactga
    34261 aacagacgat tttgtagcag ttctacctaa aaatcatcct ttagctagta aaaagaaatt
    34321 ggatctaagc gaactgaaaa aggagaactt tttgctcctt ggccccacta cgaacttgta
    34381 tcaacctgta ctagatctgt gtcgcgaagc tggatttgaa ccaaaaatct cttataaagg
    34441 agcaagaatc gacttgatca tcaatatgat tgcaaatgac atggggattg ctattgttat
    34501 ggaaaaaaca gtcaagaatc tattaaaaga aaatactgtg attctcccta tttctccaac
    34561 aacagagagt tatcttgcat ttactcgtaa agtcggtgag cattctttgg cttcagatac
    34621 attttgggag tatttaaatc aagaagaaaa ctaagcccta cattttctgt ccatctatcc
    34681 acccaaaaaa agagagcgac gcatgacttt cgctctcttt cttgcatcat gtccttgttt
    34741 caatgacacc tctaacattt ctcgtagttc aataagaaag cagcgatttt tatgccaaaa
    34801 gaaccgtaag aacatttccc taatcacaaa aaaacgacta aaaaccccta aaaaccttca
    34861 atagaatttt taggggtttt attctttttc ctattgttta cttaaccgta tcattgctgt
    34921 cgttcctact ccttcgatac tgctataatc aatacgtcca tcatgcagtt ctagaatttt
    34981 tttaaccagt gaaagtccta gcccattccc agaaatttga cgacttgtat ctccttgata
    35041 aaatttttca aacattcgat ctctggtctc ttcattcatt cctacacctg aatcggtcac
    35101 ttccagtaca atctctgtgg ctgtctcaaa tagtttgata tgaatctgtc cattgatttg
    35161 attgtacttt atggcgttat ccatgatatt cagccacact tggtacaaaa actcttcatt
    35221 gcctgtgtaa tttactgcag caagttcgat atccaattct agctgttctt tctcccattt
    35281 aggctgaaaa aaaacgatta cttctctgat ttgttcatct aatcgatact ctttcttttc
    35341 cagttggata cgctggtttt ccagtttgtt caattttaag atgttctctg ttaattgtga
    35401 aagctgcgtg atactttcga taatccgata taaaaatatt tggcgttctt cgtcagagag
    35461 atttggggct tgtaacaatt gaacatatcc ttggattgtt gctagtggtg ttttgaattc
    35521 atgggataca ctggacacaa agtcattcct cagtgtctcg atactattga gttcttggac
    35581 cataacgttg aaatctttat acagttgctg tacttctgct actttctgct gttcatccat
    35641 tcgaatcgaa aaatctcccg ttgctaccag actcatattt gtccctagcg cactgattgg
    35701 atgcaggata cgccgcccaa caaaaatcga tattcctgta cccacgacca tactgaaccc
    35761 cgcaaagacg aataacgggt ataacgttgg ttttccagcc gattcagcag gcgagataga
    35821 atgtcgagac aataagaaaa taaaaccgag aaaacacagc agtgtcacta agatcgaaat
    35881 gaagacaata ctagcaaaat agatccataa ttgtgaaaat agcttttttt tcatctttaa
    35941 ataaccgcct tatagcctag tccccgtact gtgatgattt gaaaatcttc cgtcttttca
    36001 aaacgggtcc ttaaacgttt gatatgtaca tcgatcgttc gttcttctgt attcgtatct
    36061 aatccccaaa tatcatccat caactgttgg cgagtgaaga tcttgttggg ataagacagt
    36121 aatttataca gaagcagaaa ttctttttga ggcagaatca acgaatgctg atcttgtaac
    36181 actgtataag catctagctc taattttgtt tgtccgatta tcaagctact gctgtaattg
    36241 atctttgaac gtcgaagcaa tgcttccaca cgtaggatca tctcattgac atcgatgggt
    36301 tttgtcatat aatcatctgc tcctaatttg aacccgcgtt tcttatcctc aaaatcggcc
    36361 tttgccgtaa tcattagaac aggtgtgtca aatctggtgc tacgtaatga gtctagcaag
    36421 tcatagccat ccattttcgg catcatgata tctgtaatga ttaattctat acgtgtcgct
    36481 tctagttttt tcagcgcatc ctctccattc aatgcggtga tgactgaaaa gcccgctcgt
    36541 tccaacacag aacggtaaag caactgtaat tgcggatcat cttctactac taaaatacga
    36601 ttcattgatc tccctctgtt ttttgaaaaa tttctagatt ttttcttgta gttcatcttc
    36661 agttaacatt tatttcgtat actacgatca ttgttctgat atacttatta gtataccgaa
    36721 tatttcaata cgggagaagg gtgattatgc ttcaattaaa agatataaaa aaatattata
    36781 aagtcggcga aaccaccacc aaagcattgg atggtgtgtc tgtcgctttc agacaaaaag
    36841 aattcgtagc gattttaggt cctagtggtt ctggtaaaac gactatgctg aatgtgattg
    36901 gtggactaga taattatgat tccggtgata tggtaatcaa cggaaagtct actaaagact
    36961 ttaaggacag tgactgggat gcctaccgaa acaactctat cggtttcatt tttcaaagtt
    37021 acaacttgat tggtcatcta ggcattattg aaaacgttga acttgggatg acattaagtg
    37081 gtgtttctaa agacgaaaaa cgaaaacggg cagaagatgc attgcaccga gtcggcttga
    37141 caaatcatat gcataaaaag ccaaatcagt tatctggtgg acaaatgcag cgagtggcca
    37201 tcgctcgagc actagccaat gacccagata tccttttgtg cgatgaacca accggagcgt
    37261 tagatacaga aacaagtatc cagatcatgg aattgatcca agagttatcg aaagaaaaat
    37321 tagtgatcat ggtcacacat aatcctgaac tggcccatca atacgcagat cgaatcattg
    37381 aattttctga tggtaagatc ttaacagatt cccatcctca catcgaacga ccaaaagatg
    37441 atcaatttaa cttacgcaga acaaagatga gtttttggac agcgttaaag ctttccttca
    37501 acaatatccg aacaaaaaaa ggacgtactt tcttgacctc ctttgcttcc agtattggga
    37561 tcatcggaat cgcgatcgtt ctgtcccttt cttctggatt ccaaaaacaa atcgataaca
    37621 cgcaagctga aacgatggcg aaatttccga ttactatttc taaggtaacg actaaccaga
    37681 ctcgtgacga tgccggattg ggtgcaagca aagcggatta tccagacagc aaaacgatta
    37741 ctgcaaaagt cagcgaagaa gataaagcac agcacacgaa taagattgat caaacatacg
    37801 tcgattacgt aacagacatc gatcctaact taagtaataa tatcggattt acccgtacta
    37861 caggaatcaa tcttttacgt gatgtaaatg gcaaagtaca gcctgtcagc ttctcgaatc
    37921 aaaatcctga tacggaatct ctttctttat ctagtacgat gtcagcaatg acaggtgtgg
    37981 gagtgtcaag tttccctaca cagcttgaca ctagcaaaga aaacttttta aaagacaatt
    38041 attctttact tgccggaagt tatccagcct cagcaacaga tgtcgtgctg atcgtagacg
    38101 gcaataataa tactaatatc aacgcattga agaatcttgg atttgatgtg aaagaagacg
    38161 aaaaacttga ttttgatgat atcgttggta caacattcaa attagtaaac aacaatactt
    38221 actatacaaa acttccaact gggaatttta tccctaatac agattatgat gcgatgtatc
    38281 agaatgcttc tgatgaattg aagatctcgg ggatcctacg cgtgaaatct tcttctacaa
    38341 tgaatctctt atctccagga atcgcttata gcgatcaatt aacgactcaa atcgtcaacg
    38401 aaaacaaaga atcagaaatc gtcaaagctc aaagagacag tggtgtaaat gtcttaacta
    38461 ctgaaaaagt tgacgaaaat gccaaacaaa cattgcttag ttatttaggt ggagacagct
    38521 tgccttcaag tatcatgatt tatccgaaca attttgaaga caaagaaaag atcttggatt
    38581 atctagatga ttacaataaa ggcaaatcag atgaagataa aatcatttat actgatttag
    38641 ctggaacgat gactgaactg actggcggat tgatggatgc tatcacttat gtccttattg
    38701 cttttgcagg gatctcttta gtaacaagta tgatcatgat cagtatcatt acttatacat
    38761 ctgtgattga acggacaaaa gaaatcggtg tactaaaagc tttaggtgca cgtaaaaaag
    38821 acatcactcg cgtatttgac gcagaaacgt gtattttagg tatttcttct gggatattag
    38881 gtgtgtttat tgcatggcta gctacgttcc ctatcaatag catcttatac aacatgacgg
    38941 atctaaaaaa tgttgctcaa ctaaatcctg tccatgcgat tattctagtg atcgtctcta
    39001 ctatattgac gatgcttggc ggtcatcttc ctgcacgaat ggcagcgaaa aaagacgccg
    39061 ctatcgcttt gcgtgcagaa taaggttgtg acaaccacat ttagatttga gtcataagag
    39121 cgctgaaata gtagaaaaca gcaagaaacg aggaagtaat atgttccttg tttcgcgctg
    39181 ttttttttaa ttatttttta taattctggt atacttttct ttcctttgta ccacaactct
    39241 tctggcgtat acctgtcttt tccatttatg aatactgttc catctgcttc aatcgttact
    39301 tcagtcccaa tccacatatt acgagaaagt gcgagaagat tttttctttt tcctcttcct
    39361 ttttttccaa attgcaaggc atcggttatc tcttctgtcc aatgagattt cacgtatttt
    39421 acttctccgt tttcaaatgt aactttcaaa atattcgcta tattttccac ttttactgct
    39481 ttaggaaatg actcctccat ttttttcact ttccttcctc caacactaag tatgcgcttt
    39541 cttttagtga taagtatatc atagtttatt ctattatcaa aaaaacgcat ccattccatt
    39601 gtagaatact ttaccgaaca agttgaattg ttttcctctt tttcaccttt tactatagat
    39661 aggtaaagac aactaaggag gaatctctca tgacagatca accgtatgat ttaagaaaag
    39721 tcatcgaaga actaaaaaca cttccaggtc aatatcacga aacagatatt gaaatcgatc
    39781 ctgaagcaga attatctggt gtttaccgtt atatcggtgc tggcggtaca gtaaaacgtc
    39841 cgactcaaga aggaccagct atgactttca acaatatcaa aggtttcccc ggcacacgtg
    39901 tgaacatcgg aacaatggct agtcgtaaac gtgtaggtga aattttgcac catgattatc
    39961 gaacacttgg tcgtttcttg aaagacgctg tagaaaatcc aatcaaacct gtgaaagtag
    40021 acaaagcaga cgctccagca caagaagtcg ttcatctagc taccgatgca gacttcgata
    40081 ttcgcaacat tttgcctgca cctacaaata ctcctgaaga tgctggtcca tacatcacaa
    40141 tgggtgtagt cttaggatca gatccagaaa aaacaatgag cgatgtaacg atccatcgta
    40201 tggttctaga agataaagat acgatcggta tgtacatcat gcctggcgga cgccacattg
    40261 gtcacttcca aaaacaattc gaagccttga ataaaccaat gcctatcact atcaatattg
    40321 gtttagatcc agcaattgcc attggcacga ctttcgaacc acctaccact ccacttggct
    40381 acaatgaact atggtgtgca ggagctttgc gtaacgaacc tattcaaatc gttgatggta
    40441 tagcagtcga tgaagtgggt attgctcgtg ctgaattcat cattgaagca gaaatcatgc
    40501 caaatgaaac aatgcaagaa gatatcaaca cgaactcagg aaaagcaatg ccagaatttc
    40561 ctggctatac tggggatgct aatccagctg tacaagtagt gaaagtcaaa gcagttactc
    40621 accgaaaaga caatccaatc atgcaaacaa cgattggtcc cagtgaagaa cacgtatcta
    40681 tggccggtat tcctacagaa gcaagtattc ttgccttggt cgataaagct attccaggaa
    40741 aagtagtaaa tgtctacaat cctcctgcag gtggtggtaa attgatgacc atcatgcaaa
    40801 tccgtaaaga aaacgaagcg gatgaaggta ttcagcgtca agcagctatt cttgctttat
    40861 cagccttcaa agaattgaag acagtcattt tagtcgatga agatgttgat attttcgaca
    40921 tgaacgatgt agtttggact ttcaacactc gtttccaagg agataaagat atcatcgtga
    40981 tcccaggaat gaggaaccat ccattggacc catcagaatt accagaatat aatcctggct
    41041 ctattcgttt ccgtgggata agtgcaaaaa ctatctttga cggtacagtt cctttcgata
    41101 tgaaagaaca ttttgtacgt gcaaaattcc aagaagtaga agattgggaa aaatatttga
    41161 aataatgaat gatctgcaac tgttttgaca tcataaaaag gagtgcggaa aatggaacaa
    41221 ttggcacaac ggaagaaaaa aatcgtgatt ggtgtaagtg gcgcttcagg caccatttat
    41281 gccatcaacc tagtgaagaa actaaaagaa tatccgatga tagaaacaca cggaatcatc
    41341 agtccatggg caaaacagaa cttaaagctg gaatccgact tatcactaac tgaattcgaa
    41401 agcctgtttg attaccatta ttcaaacaaa gatttaggtg ctgctgtcgc cagcggatca
    41461 tttttgaccg atggaatgat catcgtaccg gcaagtatga aaacagtcgc aggtatctct
    41521 gttggtttag gcgacaacct gattgcacgt gctgctgatg taacaatgaa ggagcaacga
    41581 aagttagtca ttgttcctcg tgaaacgcca ttaaatgcca ttcacttgga aaacttgact
    41641 aaattagcac gactaggtgt gcaaatcata ccaccaattc ctgcttttta taatcagcct
    41701 caaacgatcc aagatcttgt taatcaccat acaatgaaac ttttggatca atttgaaatt
    41761 gtaaatgagc attcaaaacg ttggcagggt gattaatatg gaaaaagaaa cgatagttga
    41821 agtaaccaaa ctaggtttca cgatccaagc tgctgttaaa gtaatcggta aagacttatt
    41881 gatcacttta acaggcggag atacaccaca tatcggaaca gtcactacat tttctcgtga
    41941 tacagagatg caaactgtac gtttccctag ccacgatggt cggttccata aagacgatgt
    42001 cttagccgaa aaaatagctg tgatcatcaa aactgccgtt ccgggaagtt gtacgatcac
    42061 ttccggtatc catgttgacc atatctccaa tgcacaaatc aacgcctctt ttccgatgtc
    42121 agaagagtta ggttacaaga ttttagattg gttggaaaaa atagatttcc atatcaaaga
    42181 accagtttat tataaagatg gtgaaaaacc attatgaaag aagaggttgt gaaatcagcg
    42241 ttatgacctg agtatgagag aaaaaaatgg aaaaatagct tctcatattt tgccgttttt
    42301 gagctaatac cgagggacag ctgattgaac gccgtttatc aagaggttgt gataaagccg
    42361 cttcgtttcg agtagtaaga aaaattttgt aaacatgggt ttccacattt ttgcataaat
    42421 ttgacttact accgagaaac tggcttttga acaccgttta tcaagaggtt gtgacacgtc
    42481 ttttgtcaca acctctttta tttttgcttc actgtaactg ctacaatatc accgatttct
    42541 tttccgatgt ttttacgaat atcttttcgt agtccaagga tgtagcagac tgaaccatct
    42601 ggatttttca cgcccatatt cacgatactg ccttcatacg gcacattgtc aaaagttgct
    42661 tggactttaa ctcttccagc accgaattct tttcttatat catacggaaa aataatatat
    42721 gccccgccct tgccgacttc ggaagcatag atttttgatt caaaagaata aatttccctc
    42781 attttatttc tcctattttt tacatctagt atagcatagc aaaaaaaaga aggaactgtg
    42841 acaaaagtct tgtcgcagtt ccttttttcg aataaacggt gttctcctgc caactcctcg
    42901 gtcacaagtc acaatagtca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    42961 ctcagagtta aacggcaggc tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc
    43021 tacggcacta agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt
    43081 actgcttgat gcagagcagc tttttcacaa cctcctacat ggtgttcaaa atattattcg
    43141 ccttttgctt ctttcactaa ttttgcgaat gcttgttgtt ggaattcagc agctaaggct
    43201 ttcgtacgtt gttcttgctc tgctttgctc atttttggat tttcagtcat tgcttttacc
    43261 ataccgtctt gaacataagc ttttgcttca ctttccatcg tactttgctg tttcttcact
    43321 aattcagcta acttggctgc ttggtccgta cttaattcta cccatgtctc tgggattttg
    43381 aatgtattca ctcggctgtc atattcgtga ttgttatcag caatattgaa ccagaattta
    43441 tacatgtcgt ttttgtattc ccaataagta gttttcgtca ctttttcagc atcgccgtct
    43501 gtcttttcta ctttatttgt ttcgttatcc gtaccagttg cttttggttt ttcttgtttt
    43561 tcatttgttc ggtaaagata cactttttct tttccattcc ctaaagcttt atacaaaagc
    43621 atatctgctc cttgggaatc agcactggaa acaatttttt ctgtttttgt ttccgttact
    43681 ttttccattc caaagtgatt ggacaaatta gcgacgatca aacttagtga agcgacgaag
    43741 attagtccga aaatcaaaga taaaaaggtt tgccatgttt ttttagcgaa cacgttcgtt
    43801 aaagcaaaag caagcaagct gacaatcaaa actccaataa tcatgcatta tcccccgctt
    43861 tcattagaac aggttctttt ttcttcaata aaaaggcaat aataaagcca agaatcccaa
    43921 agatgatcgc tacgataaac gcggcatggt aacctgacag tgtggcattg attgcctgat
    43981 ctttataagc taatggcgta ttatccaata cagatttgct tgggatattt gcttttgtca
    44041 cattcgtcaa cacactgatc aaaatagctg taccaatcga gcttgcgatt tgacggaatg
    44101 tattatttac cgctgtccca tgactgatca agttatttgg caatgcattc ataccagaag
    44161 tcgttaccgg catcatgacc atggagatcc caaacatacg gatcgcataa aggatcacga
    44221 tatataaaac tggagtcgtt tttgtcaaga aagcaaatgg tgcagttgcc gctgtcaaaa
    44281 tgaacatccc tgtgatggct aaacgtttcg cgccgtattt atcgaaaatc gcacccgtca
    44341 caggcatcat agcccccatg atcaatgcac ccggcaacaa catcaagcca gaatggaatg
    44401 ctgattctcc acgaatattt tgaatataca atggtacgac catttctgcc cctaccatcg
    44461 ccatatttgt tacaccagct aaaacagctg caatcgtgaa tgtagatgat ttgaatacac
    44521 gaagttccaa gaatggatgt tccaaatgta attgacgcca tgagaacaag gcgatgaaaa
    44581 tcacaccaac aactaagaaa ccaattactt tcaagcttcc ccagccgtca tctcctacac
    44641 tagaaaatcc gtaaagtaaa ctaccgaatc caatcgttga taaaatagcg gataaaatat
    44701 caatgctagg atttgacaat ggaataacac ttttcattag gaagaatgct aaaaccaaga
    44761 caagaacaac gattggcagt accataccaa acaagtcacg ccaatggtag ttatcaatga
    44821 tataaccaga taatgtaggg cctaaagcag gagcaagtcc aataacgatc cctgacatcc
    44881 ccattgctga tcctcttttt tctggcggga aaatagatag catgatattt tgcaataatg
    44941 gcatcgatac tcccacaccg caagcttgga tcaaacgacc gattagtaat gtactaaaat
    45001 taggtgctgt aaagcaagta atcgttccga tcaaaaagat cgtcatggca gaaagatata
    45061 aatttcttga actgaattta ttgatcagcc atgctgttat tgggatcatg atcccgttga
    45121 ctagcaagaa accagtcgtt aaccattgca catcagacgc tgaaatatcg aaagctttca
    45181 tcaatgtagg aaaagctgtc gtcaataagg tctgattcaa aacggtacaa aatgtaccaa
    45241 ttaataagac aacaactaaa agtgtccgat tatatggttt tccgtaaata tctacgggtt
    45301 ggttgttact catatttctc cttctttctg aattttttct gaaactacta gaatacttta
    45361 gtcctaaatt cgctatttgt caacctactt gacacataag ttaatacgga tataattaag
    45421 ggaagcaaga ggacaaaagg agtgacaaaa atggttgggg cttcccttaa acgtttgttg
    45481 gaaaatgatc aattggttgt tggcatcagt gaattaagtg atatcgtagg tgtgtctcca
    45541 cgtcaattaa ggtattggga acaaaaggga ttcattcgtt cgatcgaagc tgatgcgaat
    45601 tgtcctagaa aatatcgttt acctacagtc ataaaagtag aactgatcaa aaaatattta
    45661 gatgacggat ttactttgtc aaaagctgca gaaaaggcag aaatccgcca aaagaaaatg
    45721 caccatgtcc gtaaagtttt ttcaaaagca atcaaagata tcgaattgat cgacgaacgc
    45781 tatacgattt tacaaatcgg taacttcaaa gaagagaatg ctaagatgta catcattcat
    45841 gacaacgaga cagacgaatt aacttacaag ctccttcctg tcgatgaaaa agctgactac
    45901 gaacagttgt taaaagaact ctaaacgcca ctaatctcct aagtaccaag ctttttaata
    45961 agtagatgct acataaatac ttgaaaaaag gcctgtttga acataagaat atccgaacgg
    46021 tgatctgcgt ttctttcata tagaaaggaa ttctccatca ctgttcggat atttttttat
    46081 ttttttcggt tactttcttc taatacatct gttagccaat ttgcatattc tgtttcccga
    46141 ttgatcgcat gcgctaaaat caggtagtgt ccgtaatttt catgtttttc tttttcagta
    46201 ggaaagatcg ttttttttcg ctctaataga tgaagtcgtt tttcttcatg aaggtcacgc
    46261 tgctgctgaa taatttctac taatgccgga tcattcacgt ctttgacgaa atacaatttc
    46321 agaacaaatt cgtctcgatt aaccggtagt tcattggtgg gtgtatgaat ccactctgcc
    46381 aattgttcct tcccttcttc tgttaattca taaactttct tttccaattt ttcacctgtg
    46441 atctctactt gatgctgaat gattccttgc tcttccattt ttgcaagttc aggataaatc
    46501 tgactatgtt ttgcttgcca aaattctcct atttcatttt tgaacgattg attcaattca
    46561 tatcctgtca tcttcttctt acttaataac cctaacaaaa tatatcgaag tgtatttttt
    46621 cttgccatca gttttccctc cttgacaaat ctttaaatcc attctatcat aaatgagtaa
    46681 tcgaaaacat gtagtttatt acatgtttta atttataagg agatgcttaa acatgaaaga
    46741 atttaaagaa ttggaagatt ttattggaac tcactttatc tatacgtatg acaatggttg
    46801 ggaatatgaa tggtatgcca aaaatgacca tactgttgat taccgtatcc atggcggaat
    46861 ggtcaaaggc cgttgggtaa aagaccaaga agctgatatc gttaaattga cggacggcgt
    46921 attcaaaatc acttggacag agccaacagg gacagacgtg gcattggact ttatgccaaa
    46981 tgaaaagaaa cttcacggaa tgatcttttt ccctaaatgg gttgaagaac atccagaaat
    47041 cactgttact ttccaaaacg aacatatcgc agaaatggaa gcagctcgtg aaaaatatga
    47101 aacttatcca aaattacttg ttcctgaatt tgctacgatc acttatatgg gtgatgcagg
    47161 tatagacaat gaagatgtta ttagcgaaga accatacgat ggaatgccag atgatatccg
    47221 tagcggaaaa tacttcgatg aaaattataa acgagtaaaa taaggttgtg aaagagaggt
    47281 tgtgaaatca gcgttctgac ctgagtatta gagaaagaaa cggaaaaata gttcctcatg
    47341 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcaagagg
    47401 ttgtgaaatc agcgttatgc tttgagtaat aagaacgcta gttagaaaat agcttttcat
    47461 attttctagg ctagtgggct tattaccgag aagcagccgt ttgaacaccg tttatcaaga
    47521 ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaatggaaaa atagttcctc
    47581 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaaa
    47641 gattgtaaca actgcatatt cacacagtta aattagtgac ttcaaaatga aataatgctc
    47701 ccagcaaaaa attaggctgg gagcattatt tcgttattct gttcatcaaa aatcagcgtt
    47761 ttgattccat ttcatcacaa gttcctcctc atttactgct tcatcttttt gctgtgtttg
    47821 aattgtaaaa ccttgtgaaa gatagaaatg aatagctgat tgattttttt gatagactgt
    47881 caaagtcagt gttttattgg tttcttttat ttttttcatt agttgcgtac cgattctttg
    47941 ttgccggtat tcccttttca caaagattcc tgcgataaac tgatcaatca ccccagcaaa
    48001 accaataatt tcttgatcta tttctgctaa gtaaatcact gcatctggta aagctttcct
    48061 aacagattct acttgattct cccaataagt tgatggaatg aattcatgag aatccaagtt
    48121 agcatgcagc caaatcgata gaacagattc cagttctttg gcagacaatt ttgttgttgt
    48181 gcggatcatt ttttctctcc ttacttattc attgatttta aaataaaaac catttttttg
    48241 aagctctttt acaagttttc gcccctcaaa aaagtatatc ttctcttgtt ttacttttct
    48301 aataccaaaa gaaacagcaa ctttaggatc atcagctgaa acgattcgat aagttccacc
    48361 aggcaattga tccagcttga ctttcccatg atggtcgctt tgtactgaaa acggcacacc
    48421 atttctagta agtgtttttt tcttatgttt caaaatgaat gaactaccat ttaccggttt
    48481 ccctgacgaa tcactaataa taaatgaaaa atcaagcact tttttactta atctatactg
    48541 atagattagt cgtccgataa acactaacag tatgactaca gctattatcg ttcctgcaag
    48601 aataaaccat tgccgcatgg ttctttcctg atttcctttt ccttcttctt tttttaccga
    48661 ttcgttataa ggaatccgat gtcctgtcac tagcaaacga tgcgtgttga tcatatacgg
    48721 cgtacatgta agcaaggtaa ctaagtcttc tccttctgaa atcgttagaa cagacgtgtc
    48781 atctggcagt accacttgta tatttttaac ttgataagcc aatttctccc ccaaaacagt
    48841 caaaataaac gtgtctccgt tttctaaacg atctaattcg gtaaataacc gtcgattagg
    48901 taaaccgctg tgagcagaga tcactgaatg cgtcgaattt ccaccaagcg ggaaagaggt
    48961 tccttgcaag acgcctgctc cattttcaag gatcctacca ttgagccgat cataaagtga
    49021 aatatttaat tggatcttag gtatattgat acttccgatc agccattcct ctaattggct
    49081 ggatgttgta ctttcatttc tgttcttttc attgaaagga tcagtaccag gattgaatcc
    49141 ttggtcagtt aatcgttggt ttttctcctc cattttcttt cgctgcactt caatttcagc
    49201 tgcggtccgt ttttgtactt gttcgatacg tttttgatca ataaaactat ttaaagaatc
    49261 cacataaaat ggatataaag cgatcagtaa ccctacgacg atacatatta ataaaaacaa
    49321 acgaaacaaa agtcgacgag actgtttttg cttactctgc ttcacatgtg tcctcccttg
    49381 caagtttttt tgttctttct tttattatat gggttcagga aaaaaataga aaatgaaagc
    49441 cgatgaggtt gtgaaaaagc tgtcctgcat caagtaataa gtacagccca aaaaaatagc
    49501 tactcatatt ttttgttggg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    49561 taaggaagag gttgtgaaaa ctgcgttatg ctttgagtaa taagagcgct agtcagaaaa
    49621 tagcttctca tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc
    49681 gtttaccgag aggtcatgaa aaagctactt tgtttcgagt attaagaaaa attctgtttc
    49741 aaaacaagga gatgcaacaa aacttatgtc gcatcctctc tccttagaac tttcacttat
    49801 gtttttcttg taaaattcat aaatattttc atgaattttc taatttcttg cctacctctc
    49861 gcataggata tatgatgaat ttatctaaag tttgcaaagg agttcgacaa ttgaaaaaat
    49921 atggcccatt tttagcaatt tttttcattg ctttggcatt tctcatgcct catttattca
    49981 cacataaact aattttgggt gctgatgccc cattccatta caatcggttc tatgatgccg
    50041 cgcaacaaat taaatatggg gatttccatt attttccttc cctttatgga ttccagcaaa
    50101 gtggcaggat cgtgaatgcc gtttacggcc catttttcgc ttatttacaa ggattgatcg
    50161 tgttgcttgc aggtagctgg tttcattatc agattctttc aaatttcatt ctttatctta
    50221 tttcaggatt ttctatgctg attttactga gatatgtcaa tgttcgaaat tgggtaagtg
    50281 taccagtagc cgttttattc atgagtacgt attctattca atactggtct atcaaccaag
    50341 gattcactag ctgggggact tgtttttatc ctttatgtat gatccctatt gctgatttcg
    50401 tccttcataa aaagttccct gttatcaaag tcgctgtctc agtgggactt atgacacaga
    50461 tccatttact gtcttcgatc atgttagctt tgatgtatat ccctttttat ctttattact
    50521 tttttaacca gactgaaaaa ggaaaagcac tgcttcaact gattaagtcg gtcttgcttt
    50581 attttgttct gacagcaaat atttgggcag gattagctat tgtttacagt gggaataaga
    50641 ttcttcctcc ctttgttaac agagaaatga gtcaaaaggc gatagatctg gatggcagtt
    50701 attggctcca ttaccctaag gcctttccta tattgatatt atcaggtttt ttgcttttta
    50761 ttttctttca acaaaagaac accttattcc aaaaaatcgt gttgtacaca agtcttgttt
    50821 tcttttttct ttctactagc ttgattccat ggacgacatt gatcgaaaaa aatgtgcctt
    50881 ttattagttt gatccagttt ccatttcgat ttttcgtgcc atttacgcta ttgcttctac
    50941 tttaccttgc cctttcactg aaccagtggt ctgaacaaaa gtggttccgt cttttaagta
    51001 tatttggcat tcttattttt tcagcacaga cgatccagaa cttataccag catctggaaa
    51061 agtgggaaaa tgaaacattt gtcagtcgac atacttatct attcgatacg ccggaagaag
    51121 caaggaaaac attcttcagc aaagatatgt ctaccagctt gttcgttttc caaaaaacca
    51181 cacctgacta tctgccaatc tataaggaga caaaagacaa taaatacgac cggtataacg
    51241 aagaaatact agaaaacgaa acaactttta taaaaacaca tccaggcggt cttttgacaa
    51301 tcaagtggaa aaacactggg gacaaaactg ttcatatccc tgttatcgtc tacgatcgga
    51361 ctgtgctaca gcaaaatgga aaaacattga ctgattatga agtaacagat atcgggaccc
    51421 caatcgtgaa gcagcaaaaa ggaatcaacg agctcacgct tcattatcaa acgccaatct
    51481 atttctattt cattctttct cttactttga ttggctggtt taccttgcta tgtttattta
    51541 tttatcatag atacaagctt ttacgtgctt aggcaaaagg gataaataca tccgatcaaa
    51601 aaactctcca aacggtataa tcgtttggag agttttattt taatcagttt ttttatgtta
    51661 tatgttatat tttttattcg ttcacatcta attcgatttc caccccgtag tgatcactga
    51721 tgattggact atcgatccca tcaaaaatcc gttgatattt tttaacctgc attccttcag
    51781 ggacgaaaat aaaatctata cgcaattttt ctgtattttg ttcccaacca tctattttct
    51841 tttccacagt agctgctttt cctttttcat tcgcgacaac atacgaatct tgaagaagaa
    51901 ggcaactttc tcttacagta taataacctt gagagtctac tggattattg aaatcaccta
    51961 ggaaaaaaag tggtacgcga gtttccaaaa agtagttttc caagtttttc cactcaaaat
    52021 aaaagccact ttttttatct gtccaccaag aaaagtggca gctcgagaca aaaatgtcct
    52081 gatcatctat ctttgttttc ccaatcaaga tcttgcgtgt ctgataatct tctttctttt
    52141 gaaattggga gacggtaagg acctgacttt ccaatgtttt tttcgtaagc agtgcatttc
    52201 cttcttcata tttatcataa ccgatgtggc tcatttccca actccaaaaa tactcttttc
    52261 cgtgttcctt taaaagctga actaaacggt aggcaaaatt atctttacgg ataggtactt
    52321 gattctttac cggacagaac ttcattagct tcgcaggttc tacttcttca gattccagta
    52381 attggttgat ttcttgtaaa gcaatcactt cataatcttc taacaggatc ttatctgcta
    52441 attcttgcaa ttttttctct ggttctggct caagccagct atgcgtgttg agtgtcatga
    52501 atttcattgg ttttctcctt gtcttcattt cgaaacaaaa gggttgtgac aaaatttttg
    52561 tcacaacctc tccagcaaat agtgttctcc tgctaactcc tcagtaataa gctcaatgga
    52621 ccaggagcta ttttttgttt ggctgttttt atcacttggt gcagggcagc tttttcacga
    52681 cctctccact aaacagtatt caaactgctg cttctcggta ataagcccaa ccaaacgaaa
    52741 aataggagga gctatttttg tttggctgtt cttatgactt gatgcaggac agctttttca
    52801 caacctctcc ttacatttta atggagccga tcactttacc agctgtcact gtacctaatt
    52861 gcttgatcac tacttcttct actttatcgt ttgtaaatac gatcatgatc gttggatctt
    52921 tttcttcgtt ttggatcaca tcaagatcca tctcagctaa tttcgttcct gttcctactt
    52981 cttggccttc tttgacagca atctcaaaag ctggctgatt catttggact gtatcgattc
    53041 ccatatggat caaaacttcg ataccatctt tcgtttccag cccaattgca tgtttgctag
    53101 ggaaaatact tgtcactttt ccagcgatcg gcgcaacaac ttctcttgat gttggaataa
    53161 cagcaaagcc gtcacccatc attttttgtg agaataccgg atcttttact tcagataaag
    53221 gaatcacttc tccagaagct gcggaaacta gttcttgttc tatacctaag tattgcttac
    53281 tacctgcttg tccatttcct gtagaaacca tttctggctc tggaatctct gctcctgatt
    53341 gcagcagatc ttcgatatct gatttcaaga catctgcttt tggtccataa actgcttgga
    53401 ctccattgtc tttgacgatc aatcccatcg cccctgctcg tttccaggct tcttcagtcc
    53461 ctactttttc tcgatcattt acacttacgc gtaaccgagt catacaagca tcgacatctt
    53521 tgatattttc ttttcctccc agcaaatgaa tgatctggac cacttgctga tctgctgttc
    53581 ctgttccgct gttagataca acggtttctt cactgtcatt gtcgtaattt ccgttacgtc
    53641 ccggtgtagc aaagttgaat tttttgatca agaaatttgc taagaaatac gtaacaacac
    53701 caaaagcgat cacacacaac acgaagttga taagatctcc acctagaccc gctttgatag
    53761 ctaacggtgt ccgagtcagc aattcgatat tcccaaatga atggacccgc aatggcaaga
    53821 tatctgccat cgcaaatgca gccccttgga tcactgaata aatgacatat aatggcacag
    53881 cagcaaacat aaacatgaac tccaatggtt ctgttacacc tgttagaaag acagccaacg
    53941 ctgctgaaaa atacattgat ttatatcttg ctttcttatc aggatcgaca ttacgataca
    54001 tcgcaaaagc cattcccatc aagatacctg aagaaccaat catttgtcct actttgaaac
    54061 gagccggcgt ccagttatgc aacacaaact catattgcga catatcccct gcacctttaa
    54121 gattcactaa atcagtggcc caagccaacc ataacggatc ttgcccaaat acttgtgtcc
    54181 ccgcctgtgc gcctgataaa atctcatacg atccgccaag ctgtgtatag ttgataggaa
    54241 tcgtcagcat atgatgcaat ccaaatggca atagtaaacg ttctaatgtt ccaaataaaa
    54301 acggtgctag aatcggtgcg ctttcttgtg attctgcaat ccataaacca aaattattga
    54361 ttccagcctg tacgtttggc cacaccacag caagaatcaa tgccacgatt gttgaccata
    54421 agataacaac aaacggaaca aagcgctttc cattgaaaaa tgacaaagca tccggcaatt
    54481 ttctataatt atagtactta ttataagcca ttgccccgac aaatccagcg atgatcccta
    54541 cgaatactcc catattcaaa gctggtgctt ccaatacact tgtaaaaaat cctttaacca
    54601 tgatcttcgt accgaacaga gtgtgggtaa atgcatcttc attcgcaagc atgtcacttg
    54661 tgacaccaaa gatagcccca gtgatccgat tgattaaaat aaatgagatc ccagctgcaa
    54721 atgctccgcc tgctctttct tttgcccaac ttcctcctat tgctaaagca aataaaatat
    54781 gaagattacc aataattgcc caaccaatat tttcaattac tccgcccgtt gtgacaagcg
    54841 gcgtccaatc aggattgatc aagggaattg atttccctat actgatcatc aacccagctg
    54901 ccggcataac tgctaccaca accattaaag cctttccaaa tttttgccaa aactcaaaac
    54961 taaatatctt tttcattccg tttagctcct ttacgcaatc ggtttcgtta aacgtattat
    55021 agcgtgcgtt ttcttttttg taaatgcttt attttttatt tttctgtcta taccattcta
    55081 taaaacctat aatacgtgtg ttcccttcta taattttctc ctaaaaattt atttttttaa
    55141 gcttttttct atgaaatatt ttcttttgtc tattgacttg tgcaatcggt tgcgtttatt
    55201 atgaacgtat aaaacagctc attaggagga gaaaaatgaa acagatcaaa cgactatttg
    55261 ctattgatcc atggaaaatc agcacgacac aattagataa aaaaaatctt cgactgcaag
    55321 aatctttaac aagtattgga aacggttata tggggatgcg cgggaacttt gaagaaactt
    55381 actcagggga ccaccatcaa ggtacttatt tggcgggtgt ctggtatccc gataagacac
    55441 gtgtcggctg gtggaaaaat ggttatccag aatactttgg aaaagtgatc aacgccttga
    55501 actttatcgc gatagatatt tcgatcaacg atcagctgat cgacttggct tctttggaac
    55561 cagaagactt ttactgggaa ttagatatga aaaatggtgt attatctcgt acattcacaa
    55621 tcactacttc tactaataaa gtacgcattt ccttcgaacg ttttctgagc attgtcaaaa
    55681 aagaatcagc ttatatctat ttaactatag aaatgcttga aggtagcgga acagtcaaac
    55741 tcgtatcaaa attggatgga aatgttcaaa acgaagacag caactatgat gaacattttt
    55801 ggaatgagat tgatcgtgga actatagaag aaatcggcta tttgacgact aaaactattc
    55861 caaacaactt tgggattgaa caatttactg ttactgcagc aatgcgccat ttcgttaatg
    55921 gaaaatcagt catccctgac tatcacgaag atactttagc attacatggt tgcttgtctg
    55981 cagaattatc tcaaggtgag acatggtcag tggaaaaaga aattatcgtt cttactagta
    56041 gagatattcc agaagcgcag caagcagaaa aagctgtctc agaattaacg aaccagacaa
    56101 acaattatat ccaagcaaaa gaagagcaaa cagcggcttg ggcagaacga tggaagcttg
    56161 ccgatgtggt catcgaagga gacgaagaag cacaacaagg tattcgattc aatttgttcc
    56221 aactattctc tacttactac ggcgaagatg aacgattgaa tatcggcccc aaaggattca
    56281 caggagaaaa atacggcgga gccacttact gggatacaga agcgtatgct gtccctcttt
    56341 atcttgcttt agccaaacct gaagtaacta agaatctgct gaaatatcgg cataatcaac
    56401 tgccgcaagc aatccacaac gctcagcaac aaggattaaa aggcgcgctt tatcctatgg
    56461 tcaccttcac tggtgtcgaa tgccataacg agtgggaaat cacattcgag gagattcacc
    56521 gaaatggcgc gattgcctat gcaatctaca attatacgaa ttacaccggc gatacggaat
    56581 atttgaaaaa tgaaggactg gaagttttag cagaaatcgc acgcttctgg gcagaccgtg
    56641 tccatttttc aaaacgagca aataaataca tgatccacgg tgtgaccggc ccaaacgaat
    56701 atgagaacaa tatcaataac aattggtata caaatacgat cgcagcttgg gtcttgcgtt
    56761 acacgcgaga aaattattta acttatcaaa aagaagctgc tatcactatc agcgaagaag
    56821 aactagccaa atggaaagat atcgcagaga acatgtactt cccagttgac gaagaattag
    56881 gaatctttgt ccagcatgac acattcttag ataaagatct catgcctgta tccgatattc
    56941 ccacaagcga tcttcctctg aatcagcatt ggtcttggga caaaatcctt agatcttgct
    57001 tcatcaagca ggcagatgta ctacagggga tttatttctt caatgatact tttacaaaag
    57061 aagaaaagca aaaaaacttt gatttctatg aaccaatgac tgtccatgag tcttcccttt
    57121 cgccaagtat ccattcgatt ttagcagcag aattaggaat ggaaagcaaa gctgtagaaa
    57181 tgtaccagcg aacagctcgc ttggatttgg ataattacaa taacgacaca gaagacggct
    57241 tgcacatcac ttccatgact ggtagctggt tgtcgattgt ccaaggattt gctcaaatga
    57301 aaactaccca tgatcagttg agattcgcac catttctgcc aaaaacttgg aaagcttatt
    57361 ctttccatat caattatcgc ggacgtttat tgttcatctc agtcacagat gaacaagtta
    57421 ctttcgagtt attagaaggt tctcctctag aaatttacgt ctatgaacag tcttattctt
    57481 tagcggatcg tctagaaata acgctaagaa aggaggaagc aaatgtttaa aggggtattg
    57541 tttgatttag acggtgtcat taccgatact gctgaattcc attatcgtgc ttggcgaaag
    57601 cttggtcagg aaatcggcat tacgatcgac cacacattca acgaacagct aaaaggcgtc
    57661 agccgagaag actcactctc tttgctttta gcttatggcg gaaaagaaca ctctttttca
    57721 aaggaagaat ttgcagaatt agcgaaaaga aaaaacgatt attatttaga gatgatccag
    57781 acgatcgaac caaaagatgt cttccccggg gtcgtgcctt tactggattc tttaaaagaa
    57841 gaaaaaatca agattgctct tgcttctgca agtaaaaacg ggccattcct acttgaaaaa
    57901 atgggtctta caccttactt tgatgctatt gccgacccgg cagaagcaac aaacggaaaa
    57961 cctgcgccag atatcttcct ccttgcagca aaagctgtcg gactaaaagc agaagaatgt
    58021 atcgggatcg aagacgcgca agccggtatc caagccatcc tctcaagtgg cgctcaacca
    58081 attggcgtgg gacgtgctga agaccttgga gaggagatcc cgcttgtccc tgatacgact
    58141 tttcttacga tcgattactt gaaagaaaag tggcatgacc atggataatc cagagatctc
    58201 cgtcgtacca gttccagaga ctgaaataaa gaaaatcaca ttgaagaacg actacttaga
    58261 agtcgttctt ctcaattacg gtgcccgcct gcaccaaatc ttcgcaccag acaaagaagg
    58321 aaaatcagaa aatgttttat tgtcttacga tcgtttcgaa gatgttctaa cagacaaaag
    58381 cttttttgga gcaactgtcg gacctgtagc cggaaggatc cgggatgctt cttggggtga
    58441 gcatagattg gagaaaaact gcggatcaca ccatatccac ggtggcacga aaggctggtc
    58501 tttccaattt tgggaagtag aagttttcaa aactccatca tcaataggtg tggtctttta
    58561 cttaaaagat gaattttcta cctatccagg accaatcact gctacgatca cttaccgttt
    58621 aacaaaaaac gaattagaga tgacaacctc tgctagtagc cttgttgaaa ccatctgcaa
    58681 tccgaccaac catgcctact tcaacctttc aggaaatgga acaagagaca tctatgaaca
    58741 tcagttaacg gtctttttag atggtgtgct tgaattagat caagaaaaac tgcctactgg
    58801 aaattggaca aaaaaagaaa aactgccaat cgactttaga aaatccccaa cactgcaaga
    58861 gatccttgca tgttatccag atggactaga tgatgtattt cttttgcatc atcctaggct
    58921 ttccaaaact tccttacaat tattcgagaa gcattctggt cgccaaatga ctatagcaac
    58981 ttctaataaa agtatggtat tattttctac gactggattc gaagctgatt tctctgtcaa
    59041 tggaaaacag atgcattcaa actacggatt agcaatcgaa ccgcaagaaa tccctgatat
    59101 cgttcatttc cccaaatttg gatcgatcaa cctccatcct ggtcaagaac ggatcagtca
    59161 gacgatttat cggttctctg cacaataaca agagaaaggt gtttttatca tggctattac
    59221 cgtaaaagat gtggcgaaaa aagccggtgt tgccacctcg accgtctctc gtgtcatcaa
    59281 cgatcatcct agtatttccg agacaacaaa gaagaaagtc cgaaaaatta tggatgaact
    59341 aggttatgtt cctaacatga ctgcccgcaa tctaggaaaa cgcatttcca gtgccatcgg
    59401 cgtaatctta ccccctcttg attcaaaaga gcggatcggt aacccatttt atcttgagat
    59461 catggaagca atcaacgaag aagcgcggaa ttatgatatg actacagcaa tcgctactgc
    59521 taaaaatttt gaattgctgt tagagaacgt ccagcgtatg catttacaaa aacaagtaga
    59581 tggttttatt ctagtgtatt cagatagtca agatactgtc attgattatt tataccaaaa
    59641 ccacatccct ttcactttga tcggacagcc ttatcatcat gagaacgaaa tcgtttatgt
    59701 agataatgat aaccagcttc taggtaaaca agcaacagaa tttttgatcc agaatggaca
    59761 taagaatatc ctgtttgtga caaacacgac tcatgaaagt ttgtatttcg aacgatattt
    59821 cggttatcaa aaagcaatga tgatggctgg tcttcctgcg ttatccagtg tagtactaga
    59881 gcatccggag gattatctgt cctttgagaa aacgttgaaa gaaaacgaag ccacagcatt
    59941 ggtggtcatt gacgatatct tcgcccttcg cacgatgcag ttggcgcaaa tgtatggcta
    60001 tgtcattcca gagacactct ccgtcattag cttcaacaac tcgatcttct caacattaac
    60061 acacccttac cttacaagta tcgatatcga tatctccgaa ttaggacgtg tcgctatgca
    60121 aaagctgcgc gaattgatcc atgaagaatt gagcagtggc gtacgtttgg tcatccctca
    60181 tcgcttgatc aaaagagaga cagtcgttcc tttagaaaac ccatactaaa tagctgactc
    60241 actaaatacg ctgaccattt atcctatggt cagcttttta tgtaaaagaa gatactactt
    60301 ctaacacatt gtttatctgt aaaaaagagc gtgggacaaa agtaaagaac acttttgtct
    60361 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    60421 attcacaaaa atttaaaaag caattttctt gagtttcttc ttatttcttg gagttaaacg
    60481 cttctgtccc agcctctttt ttccttcctt caatttttta cacgtcgacg attcaataaa
    60541 aaaccgccta atattgtaaa gacaggtgca agaatcgaga aaaaggcgaa tggcaagtaa
    60601 tgcaacgcgc taactttcat cgttcccata atgaatgtgc cgctgactcc ccacggtacg
    60661 agagaattga cggtcgcacc tgaatccgct agtgttcgtg tcaaataggt ttttgataag
    60721 ccaacgtcat caaaagaacg cttgaatgtt tctcctggaa gaatgatgga cagatactgt
    60781 tctccaacga tcagattgat tccgatacag ctcaaggcag taaacccgac taaacgagaa
    60841 ggtcggtcca tcttttcttt taattcttga acgatggtat caacgatcag atatttgatc
    60901 agtaacccac ctaatgccaa tgcaagtaaa atcaaactag cagaacctaa catactcatg
    60961 atcccgcctc gagaaagcag ttcatctagc tttggatcag gtgtatttgc gacataacca
    61021 ttcatcaaga tgtctgctgc ttttccgacc gtcaaacttt tctcatggat aaaagaaaga
    61081 acgagagcag ctgtcgatcc cgctagtaat gtagggatag ccggaatttt tttgattgcc
    61141 cccccaaata aaataactag tggaatcaat gtccaaggag agatccaaaa gctcgctttc
    61201 atgttttgga tcatttcatt gatactagct agatcggctg aatgactgtt atgtcctaat
    61261 atcgtataaa aaatcaacga aaggacgaat gctgggaaat ccgtataacg cataccagcg
    61321 atatgttcga atagattaac tcctccaata cccgctgcca agttggtcgt atctgataaa
    61381 ggcgagcagt tattccctaa aaaggcaccg gaaacgactg cgcctgtagt cattgcatca
    61441 ttgaatccaa gtaaatgacc gatccccaaa aaagcaattc caatcgtcga aatcgttgta
    61501 aatgaactgc cgacagtcac tccgacaatt gcacaaacaa gaaatgctgt cggtaaaaag
    61561 aaacgcacag aaacaagttt aaatccataa accataatcg tagggatggt tccagataaa
    61621 atccatgaag caactaagac accaatcaaa agaaaaatca ggattggaat gatccctgga
    61681 gtgattcctt tgatgatccc gtcatggatc tcatcccatg tgaacttttt aaatctgcca
    61741 taaaacaaca aacacatgaa agctgcaagg atcgggatat gtggcgagag ctggaatccg
    61801 atgatcagta ctcctaggag tgccaacaac acgatcaata cagcgatact ttcttttaaa
    61861 gaaatatttt tattcatcgt cgatctccta tttcaaatga aaaggccctg ccatgaaaaa
    61921 actattcact tggcaggacc tcctactaaa tcagcgacaa aacgtcggct gaaagactta
    61981 tttttttatt tttcttctaa acttttttct acctcaatcc cccaagaatc tttcttgaag
    62041 tgattgatga tcaatggaat aacgaacatg accactgtga tagctgctac taataatgca
    62101 tcactcaatg tcgctgtacc taatgtagca aatacgacaa cgatgataga gaagatcagc
    62161 atgcagctga ctacccaagc taatccgttt ccgtttttac caattcggta aggacgttcg
    62221 aattctggat gtttcttacg cattttaagc aatgaaacag caatcaaaat gtacacgata
    62281 caataaataa cagttgtagc atttgtaagt gtcaagaata cagcacttac gtcatccatt
    62341 acaccataaa gcaaagcaaa taatgaaata acgattgatt gtgttagaac gacatttcta
    62401 gatacgccgt atttgttttc tttatggaat ccgaattttg gtggaaggaa tccttcacga
    62461 gctacttgga tgattgtttt tgatggtcca gtaacccaag ctgataattg taaaagcaca
    62521 ccaataaata ccatgaagct gaagatattt ccgatcactt ctggtaagcc taggatttga
    62581 cagtcaatca agataggctg cgtgatattt gctaattcca tttttccatc tggtacgaca
    62641 tttgctacaa gcatcgcatt gatgacattc aataaaacta atccgatcaa agcgataaat
    62701 acgccttttg tataattttt tgttgcgtct ttcaaacgag gcatgtaaac agaactcatt
    62761 tcgatcccaa caaaaataaa tgtgatacca gctaagtatt tcaatgaatc aatatgttcc
    62821 aagtcaggga aagcttttga ccatgaaaag tcacctagat agccgtttga gactagtccg
    62881 actttgaagg ctgccaaaac acctaaaacg aacatgatga ctactgggat atatacccct
    62941 agccatacac cgatgttccc gccgactttt gccatatcga atttcaagtt caagatcgtg
    63001 atgatccagt agataactaa aatacaacct aaaacgaacc agtgattatt gccaagttct
    63061 acattaccaa atgtgtttcc taacaatggt cctaaagtag aagcgaccat taccatacct
    63121 gggaacattt gcacccataa tagccatgca acgacaaatc cccatttgct gcccagtgct
    63181 gtttttaccc ataactgagg accgccttct tgaggaagca tcgtggaaag ctcaccggaa
    63241 accattgata tcggaccggc aaaaaacaaa actgcaaaaa ttgaataaaa aatcaatgtc
    63301 caaccgactg cggctaacgt aggaatactc cgaaccgttg cacacagtgc cattgtcaga
    63361 ccgataaagg tcccaagacc cattttactt acttcagatt tactcaccgt tgacactctc
    63421 cttgattttt tggataaaat aacggtgtct ttgaagtagt ttcagcaata aacgaaacaa
    63481 ttcagcgaat atttgagggg attctttgag tttattgctt gaagggtttc ttcaaagaca
    63541 acctcaaaac aaagggatcg aagagcttag gtctcccctt gctcttcaga tccaaacatg
    63601 cgtcagaaac agttagtatt caagctgttt tctaacatga ttaccttgct tattttgctt
    63661 cgcttgccaa taattggtct gcgtagattt tttccaattt ttcttgaaga gctgctttga
    63721 ttttttcagc atattcttca aagtgttctt ctttgttcat gtatggtgtc attacgctgg
    63781 cacgcaatac agttactttt ccggcacggt tccattcttc atctgagaat cctagttggt
    63841 tcacaaattg taatgggctg ttgccatagt ctgggatagc aaagtcagta tgtgaagtta
    63901 agaactcatt accgtaaatg cttcctttca cgtatgaaga ataatcatat acgtcatggt
    63961 tcaatttatt cattgcaact aagtcatcgt tgcctttttc tttgaataca tagtctacca
    64021 tattgaaatc tggataagtt aatggatgaa cttcgatttc tttgtctcct actttaaatg
    64081 acaagtcatt caagaagttg tagaaacgat gtgcaccttc gattgatgca cccattaatt
    64141 taccatatcc tgtgacattc aaaggtaaga catggtgtgc tgcccaaacg ctggctgctg
    64201 ttgcccctgc ttttgaacct tccaagatat aagccccaag taatgctggg atatctgcgc
    64261 ctttttcaaa tacatatgtc gcaaagtaag agataacgtc tctcatgcgg atatctttga
    64321 tgacgatacc accggcagaa tatggaacat agcccatttt atgtgggtca atcgttacag
    64381 attctgcttc ttcgattgct ttatatgcac tgtgtacttc ttctaagata taatctttgt
    64441 tttctgtaaa gacattgtat ttgtaatgaa catcttttaa atcttcaaat ggaatgaagt
    64501 tgttgtcttc gtctaagaaa atcgcacggc cgtatccgcc ataagcagca tctacgtgta
    64561 agtagaagta aataccgtct ttttctaata cgcgacgcaa tgcaacgatt ttatcgatac
    64621 cgtcgattgc tccttcttct gttgatccta caacaccgac tacacctagg attggtgttt
    64681 tttcagctgc tagaccacga acgatttttt caagttcgtt gatgtccatg cgatagttgt
    64741 ggtcaactgg cactggaatc acttggtcta aaccgatacc gatgatgtcg gcagctttta
    64801 gccatgaata gtgtttagtt tgtggaacca accattttcc taatttttct aaatgttttc
    64861 cgctacgtgc tgagtgagct ttgatttcgt cgattttttc tgggacgctg tctaacagat
    64921 tcatgatttc ttctgttgac aagttcatta attcccaatc gctttttcca gcaactagtt
    64981 caggtgtcac ttctttcatt gcaagcggca atgatttgat gttgcgggca taccaaagtc
    65041 cttctaagtt tgctaaagaa ccatcagcaa cgatgtggcc ccagccatct ttatagctca
    65101 ttaattttgc aaattccatt cctacttctt cttccatttg gcttgttgca ggagaagatt
    65161 cataggcaac gttattacca ttccatagca tagcaaaatt gtacgctagt aaagatggca
    65221 tcaatgtttc agagttcata tgaccccagt aacgtccggc attatgccaa ggaacggaat
    65281 gggtacgcat ccgcgctgaa atttctgata gaacatcctt tgttttattc acagtgtgtt
    65341 caaaactagc actgcttttt tcttctggcg taataatagg catgtcttga ggcatgtagt
    65401 tttgacgcca gcctaaatgt tcatccacca attcattcaa caaagcttta tagatttggc
    65461 cgttctcagc tttgtcccca atgaataggg catttaggtt tagatctttc gacaatgatt
    65521 cactcatagt gaaaccctcc taaaaaaata tttaaatttt gtcgagccct acattacacc
    65581 tgttcttcta ttctgtaaac taagttttgg cctgattttt aatcatattt taatatgtat
    65641 caattatccg aattgttcac acttttgaaa taattaaaaa aaacgaggga atttacaaat
    65701 gtaaactccc tcgcaaagat tgtattaacg acaaccagcg ttctatttta ggatgggttt
    65761 caaaattgga atgttgtaat agtatttccc ttttttaagg taaaaactta ctaaattcta
    65821 atcaattact ttggccaaaa agtaattttt cttacctttt cgaataacca caaacttacc
    65881 atcgaattca tcggatggat ttatgacaaa atttaaatcg gtaacgcggt caccgttaat
    65941 acttatagct ccgtttgaaa catcttcacg tgcttgacgt ttagatggtt caatttttgt
    66001 ggaaacaagc agttccacga tattttcagg tgtgcttgaa atttcaacgt tcggcatttt
    66061 accgaatcct tgcgcgattt cttccgcatt tagttcttta atatttccag agaacaatgc
    66121 ttgcgttatt ttttgcgctt ctttcaagtc ttcttcacta tgcacaaatc ttgtaacttc
    66181 ttctgccaaa cggcgttgtg cttcacgttt ctcaggttct gtctctactt ttttcgctaa
    66241 gtcttcgatt tcttcttgag acaagaaagt aaagaatttc aagtatttca ctacatcgcg
    66301 atcatcttga ttcaaccaga attggtagaa ctcaaatggt gaagttttct tcggatcaag
    66361 ccaaacggca ccgcctgcag tttttccgaa tttcgttccg tcagccttca gcatcaatgg
    66421 gatcgttaaa ccgaacgctt ctgcttctgg tccttctaat tttcggatta ggtctaatcc
    66481 agctgtgata tttccccatt ggtctgctcc accgatttgc aattgcacat cgtatgtttt
    66541 atgcagatgc aaaaagtcga tagattgcag gatttggtaa gtaaactctg taaatgagat
    66601 tcctacttcc aaacggctgg caacgatatc ttttgctaac atcgtgttga tgttgaagtt
    66661 tttaccgtag tctctcaaaa attcaagtaa agagattttt gacaaccagt cgtagttgtt
    66721 cacaaatgtg atatttgcat ctttaccaaa caattttctc atttgattgg aaagtgcgtc
    66781 cacgttatgt tgcacttgtt ccatcgtttg caacacacgt tctgttttgc ggccgcttgg
    66841 gtcgccgatc gttcctgttc cgccgccaat cagaatatat ggatgatggc ctgccaattg
    66901 gaatcttttc atcatcataa atggaatcaa atgtccgata tgcatcgaat caccagttgg
    66961 atcaacgccg caataaagtg aaatgctctt ttcttcaacg agctcgcgaa gtctttcttc
    67021 gtttgtttgc tgattaatgg cgtcgcgcca agttaattca tcaataatat tcattttact
    67081 gacctccgtg tagttttttt atgaaagcag gaacctgcta gcatatgtaa ttaattattt
    67141 cttcaggata ggataggaaa taaaaaaagt cccttggcat ataagccaag ggacgaaatc
    67201 tcgcggtacc acccaatttg tatgtctaga tatccaacat acctctcgaa catttaacgc
    67261 tgtcgcgtgg caatcactgc caaagactcc tgaaatgtaa ttcgctttaa agcatgtact
    67321 ggtttgcagc gaccaccagc tttctgaaac attggcttta acaactactt cgtttcgatc
    67381 ttcgtcttgt tattattaat atgtgtctat catagagcgc aactttttct ttgtcaacag
    67441 aaaaaggata ttttttttaa attcctcatt ttttcttttt tgaatccgct ctaattccga
    67501 acattttatt ttcaattatt gttaaaagaa ataacttttt ctgtattttt tctgcaattt
    67561 atcgagaagt cactttactt tgcctcttat tctttcttcg ttacaataag gaatgggaca
    67621 agtaaaaaaa tgaaaaagca agggacgagg tatatggaaa aaaagcaaaa aattatttta
    67681 ggagccactt ctgctttaac tatcgttatt ttaattctaa gtttgttttt tgtcatccga
    67741 tcatctacaa aaaaagaacc aatcattcct gaaaaaaaaa taacagaaaa agcaaaagaa
    67801 ccgacagatg ataagcaaca actagttact caagcaaaaa atctggctca aagctacgat
    67861 tatgaccaag cgattgcgtt attggaaaaa gatagtaaga acggatctac tgaaacacaa
    67921 cagcttcttc aaacactaaa aaaggagaaa gaacaactga tcgactggtc tgatcctact
    67981 cagatctctc atgtcttttt ccacagcttg atcgtggacc cgcaaaaagc cttccactct
    68041 caacaggcac aaggatacaa agattatatg gtgactgttg aagaattcaa ccgttcgatc
    68101 gaacaacttt atcaaaatga ttttgtttta gttaatttga atgatttgat ccaaaaagac
    68161 gaacaaggaa atctttcctt taacgggctt gcgctacctg aaggaaaaaa accattggtt
    68221 ctttcacaag atgatgtcag ctattatgaa tatatggata attccggttt tcctagccga
    68281 ttggtcgtat caaataacaa tgaaatcaaa aatgtctata aagagaaaga taaagaagaa
    68341 atcggtgact ttgacatggt tcctctgatc gatgcctttg tcaagaaaca tcctgatttt
    68401 tcttatcgag gcgcaaaagg taccttggcc ctgacaggtt acaacggagt tttaggttat
    68461 cgaacatcaa aatctcaata tggagacaat gaaaaaacaa aaaaagagat taaagaagct
    68521 aaaaaagtgg cggaacagtt gaagaaagac ggctggagct ttgcttccca tacatggggt
    68581 cacttgaata tgactcaagc ttcactagaa gatgtaaaaa aagacaatga attgtggcag
    68641 caagaagttg cacctatcct aggaaaaaca aatattctga tttatccatt tggtgcagac
    68701 atcagcgact ggcagcctta ttcagcagaa aatcaaaaat ttgcttactt gaagagtcaa
    68761 ggtttcgata ttttctgtaa tgtcgatgct tctacaccag cttggggaca attaggtacg
    68821 gatttctatc gaaatgctcg gatcaatatc gatggcattc gttttcaatc tgatttagac
    68881 ggaaaaaatc ctattcttga tccattcatc aatgtccatg atgtctatga caaagaagca
    68941 cgcgaatctg cttgatttta cgtcatttat gaaccaaaaa agccgaactg acattttatc
    69001 gtcagtttcg gcttttttat gctttatttc ttcttcggtg cgattccctt gatcaggact
    69061 tctgtccatt ctgctgtata tggaagcagt tttgcgtata tctccggctt agaaattcct
    69121 tctaccattg cttgaaaata gaggatcaag aactcatccg aatatttcaa atccactttt
    69181 ccttctttcc gccctcgatg gaaaagatca agcatgatac tgaaactttc ttgcgtatac
    69241 gcatccatcg cgtcagaaaa ttcttttttt tctttttttg tatagtatgt catcaaatcg
    69301 atataaaatt gtttgttcac tcgattgaga taacggattt tgttttcact catggcaatc
    69361 agtgtttctt caaatggaag attttccgca atcaacgctt tcgcttcttg ccctaaatca
    69421 ttcataaatg caaaaaatac ttcataaatc agcccttcct tgctgccaaa atatttaaaa
    69481 atcgtcgctt tacttacctg agcgttctca gctaccttat ccattgtcac tccagcggtt
    69541 cctatgtctg tgttcatcaa gtcaaaagct gcttgtaaaa tctctttctt tttctcttgt
    69601 gctctctttt caaaaccgtt catttgtaga gcctcccgta attttaaact tttataatat
    69661 gtatagttca aatttattct gaggtttatt ataactatct attgagaaag tatcaagcta
    69721 gcaattcctt gtttatgaat tcattgacag aaatttataa aaagaatatt atgtactaaa
    69781 ataataaaaa aagttttata aaaaggtata aaaccttttt attaaactat ttaatcttgt
    69841 ttagtatata tttttagaaa aaggagtggg gtttttatgg cagaaatcgt caaagtcaca
    69901 catttgaaaa agagctttgg tcgtttcgaa gctttaaaag atgtctcttt caccgtacat
    69961 tcaggtgaag tcgttggatt tatcggacca aatggttctg gaaaatccac gacgattcgg
    70021 acacttttag ggattataaa aaaagacggc ggaacggcaa cgatttttgg gcaagatgta
    70081 tgggaagata gtttatctat ccatgaacgt ctttcttatg ttccaggcga tatctctttg
    70141 tggggaaatt tgactggagg agcgatcatc gatctcttca tgaagcttca tggaaaaggg
    70201 agtgctcaaa aaaaagatga actgattcaa cgtttctctc ttgatcctaa gaaaaaagca
    70261 aaaaactatt caaaaggaaa tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat
    70321 tcggatctct atttatttga tgagcctact tctggtttag atcctttgat ggaaacgatt
    70381 ttccaagaag aagttgaaaa attgaaagaa cagggcaaat ccatcctact ttcttctcat
    70441 attctcagtg aagtcgagcg actagcggat aaagtcgtga tcatacgcga aggaacactc
    70501 gatgaagaag gaacactcga tgaattgcgt catttgactc gttcgaccat cactatagaa
    70561 acagaagcag agaatagtca cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa
    70621 ggtcacctcg ctcaatttgc tgctgataac gaagctttcg atgtgatttt agctgaagcg
    70681 tccaaattag gtgtgaaaaa atttgaatct attccaccga ctcttgagga tttattcatg
    70741 agacattatg aaggatgagg aggaagcgaa atgactgata aattttcacg ctggtccacc
    70801 cttttttctc aaaaccttag ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc
    70861 actgcttttt ctggtggttt tgtccctgcg tttgaagaat tgacttccgg acaaggatta
    70921 gctggattat acgaaacctt gcaaaacccg gcaatgattg caatggtcgg accaactcca
    70981 gcttcgaatg ctgctgagta tactttagga gcgatgtatg caaatgaaat gttgcttttt
    71041 tgcagtttgt ttgctgctgt gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa
    71101 gaagaacttg gtctgattga acttattcgt tcctttcgag tcggacgtca agcaaactct
    71161 ttagctgtca tcgctgaaag tattctgatc aatttgcttt tagcaatatc gatcagctgt
    71221 acgatgattt ttttccaagc ggattcgatc actgcagaag gtgcttggct ttttgggcta
    71281 tctgtaggta gtatggggat tttggggagt gccgttgcac tgtttgctgc acaactgatg
    71341 ccaagttcag ccagttcgaa tggtctgtct ttagcgtttt taggtggact ttaccttcta
    71401 cgagcaataa cagatgtagc tgattcctcc ctttcgatgt ggaatccttt aggctggtct
    71461 tatttgacct atccatttac aactaacaac tggattcctt tgctttattt gtttttgttc
    71521 agtctaatct tgataatcag ttcatttgtt ttagaggaac atcgagattt gaacaccggc
    71581 tatatccccg aacgtgaagg aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt
    71641 ttattattct atctaaataa agggatgaca atcagttggc ttatcacttt tggtttgatg
    71701 ggggcggcat acggctctat ctacgggaat atgcaacagt ttttagaaag taacgactta
    71761 atgaaacaga tgtttatcca atctggcgtc tcaattgaaa aaaactttac aagcacgatc
    71821 atggtagtct tgatttgtct agctgctatt ttaccaattg ctagcatcaa tcgtttattt
    71881 acagaagaaa cccacggacg tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa
    71941 ctttattgga ccaatatgtt actagctatt ctatttgcta tattggcaat cctgattagt
    72001 tctggtgcac tagggctttc tgctttggct tcgatgaagg atgcgaaaga catggatcta
    72061 ttgatgtttc ttaaagccgg gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt
    72121 agtggctttc tattcggatg gcttcctcga atcggtaaac ttgcttatat ctacttagct
    72181 tactcctttg cactcaatta ctttggcgga attttggatt taccagaatg gttttccaaa
    72241 acagctgtcc ctagctgggt tccacggatg ccaaacgatt cttttgatct ttccgtgttc
    72301 cttacgttat catgtatcag ccttgcactg ttcgtccttg gttctattgg ttataggcga
    72361 agagacttac tagaaggata ataaaaaagc atgtacaatt tcatgctagc ctccaaatct
    72421 gggtcaaaaa tccaacattt ggaggtcatt tttttattta caagtcttct aactgctctt
    72481 tatcaatgat ccagacttct cgattctttc tttttacata accattctcc tctaataatt
    72541 taaattttct agataaagtt tcgggggtcg taccgataaa tgcagcaagt tctttcattt
    72601 tcattggcag gaaaaagtga tccttccctg tcgctttagc taagtcaagc agatagacag
    72661 cgactcgttc ttctactttt tccatcatca aaaaagttgt ctgctgctgt acttttgtta
    72721 atttctcaac gttgattgct aaaagtttca gactaagggc gggataatgc agtaagagtt
    72781 ccgagaaatc tttttgtctc aatatgcaaa tttccgtttt ttctagtgct tcgccaaata
    72841 aagactcatt tggaacgcct agcaactggc tctctccctc atatccgccc ggctctatta
    72901 ctcgtaaaag ctgttccttt ccgctagcag ataattgata cactttcata ctgccggagg
    72961 ccacgatcac taattgaggt tctccattcg gcgcaagaat ctgttctcct ttttccacat
    73021 agtgatgttt gacaagtgcg tgtacttttt cttgatcttg ctgtactaag tgattgaaca
    73081 aaggaacaaa tgaaacacat aaatgatcat gactcataat ctctcctcct tctaaacagc
    73141 tatttctaat aaagaaacat aacttccctt attccaactg ataattttct tttatcatag
    73201 cataaacgtc aagcgaacca gataccagca aatagagtgg atttcttttt gtcccttgct
    73261 ttattttcct tcttttgaga ccttaagtaa ttgattccta tcaatttttt aaatatttac
    73321 tttttgaata atcaaaaaca aaccttcact cgcaagccga gagtaaggtt tgtttttcgc
    73381 attgcttatt tcgtgttgtc tattgaaatt tttccgcacc tagcttttga tatagtggtg
    73441 ctagttcttg taaggtttca gcggttattt gctcaacgtg ttcgatttct tgcggataga
    73501 agaatagttt acccatttga aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt
    73561 tctttgtatc ggacaaatag tcagacaaag ctaagtggtc gtcaagttca tgttctggtt
    73621 gcggccatat gtaataatcc ttgatatcga ctgttttgct ccactctttc agtatcgcaa
    73681 gcaactggtt atacgctgca atgctaccat atcgttcttc gcttttataa tgttggtaca
    73741 tcaaatagat ttggtattgt ttttgattca acaaaactgc tagacaggca ttctcgtctt
    73801 gacgagattc gcttcggtac gcgctccaaa aatgactgcg taaattccag ccattcgtcc
    73861 agctttcgat tttaggtttg ctcatgccgt acatatcagg caaaagtgca gctgtctgga
    73921 gctgaatctc tttccatttt tgccagtgtt ctttatattc tttcttgatt tgttcaatct
    73981 tatctgttgg atggctctct ttgagctgtt tgaatgcgta gattggtcga tcaaacaact
    74041 gataatctga ttttccaagt tccattgttt cgcctctttc cgttatcttt tgtattctac
    74101 ctgaattttg cgatatggac aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata
    74161 agaacagcca aacaaaaaac tgcgatgagc atcaccgcag tttt
//
LOCUS       DAIGQM010000002        73749 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.002, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000002 DAIGQM010000000
VERSION     DAIGQM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.002"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(218..934)
                     /locus_tag="NOA48_000064"
     CDS             complement(218..934)
                     /locus_tag="NOA48_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0788379.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(935..2758)
                     /gene="glpO"
                     /locus_tag="NOA48_000065"
     CDS             complement(935..2758)
                     /gene="glpO"
                     /locus_tag="NOA48_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCI0788380.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(2772..4268)
                     /gene="glpK"
                     /locus_tag="NOA48_000066"
     CDS             complement(2772..4268)
                     /gene="glpK"
                     /locus_tag="NOA48_000066"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCI0788381.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(4404..5864)
                     /locus_tag="NOA48_000067"
     CDS             complement(4404..5864)
                     /locus_tag="NOA48_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788382.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(5854..7149)
                     /locus_tag="NOA48_000068"
     CDS             complement(5854..7149)
                     /locus_tag="NOA48_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0788383.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(7481..8158)
                     /locus_tag="NOA48_000069"
     CDS             complement(7481..8158)
                     /locus_tag="NOA48_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCI0788384.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(8188..9279)
                     /locus_tag="NOA48_000070"
     CDS             complement(8188..9279)
                     /locus_tag="NOA48_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCI0788385.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(9380..9814)
                     /locus_tag="NOA48_000071"
     CDS             complement(9380..9814)
                     /locus_tag="NOA48_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0788386.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(10398..11855)
                     /gene="ascB"
                     /locus_tag="NOA48_000072"
     CDS             complement(10398..11855)
                     /gene="ascB"
                     /locus_tag="NOA48_000072"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0788387.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(11852..13747)
                     /locus_tag="NOA48_000073"
     CDS             complement(11852..13747)
                     /locus_tag="NOA48_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0788388.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(13805..15580)
                     /locus_tag="NOA48_000074"
     CDS             complement(13805..15580)
                     /locus_tag="NOA48_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0788389.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(15630..17126)
                     /locus_tag="NOA48_000075"
     CDS             complement(15630..17126)
                     /locus_tag="NOA48_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0788390.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(17320..18942)
                     /locus_tag="NOA48_000076"
     CDS             complement(17320..18942)
                     /locus_tag="NOA48_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0788391.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(19270..20583)
                     /locus_tag="NOA48_000077"
     CDS             complement(19270..20583)
                     /locus_tag="NOA48_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0788392.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(20864..21052)
                     /locus_tag="NOA48_000078"
     CDS             complement(20864..21052)
                     /locus_tag="NOA48_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788393.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKE"
     gene            complement(21072..21494)
                     /locus_tag="NOA48_000079"
     CDS             complement(21072..21494)
                     /locus_tag="NOA48_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCI0788394.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(21639..22349)
                     /locus_tag="NOA48_000080"
     CDS             complement(21639..22349)
                     /locus_tag="NOA48_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788395.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(22367..22864)
                     /locus_tag="NOA48_000081"
     CDS             complement(22367..22864)
                     /locus_tag="NOA48_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0788396.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPKHLADYLTQAYAPEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(22901..23353)
                     /locus_tag="NOA48_000082"
     CDS             complement(22901..23353)
                     /locus_tag="NOA48_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0788397.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(23488..24093)
                     /locus_tag="NOA48_000083"
     CDS             complement(23488..24093)
                     /locus_tag="NOA48_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0788398.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(24648..25283)
                     /locus_tag="NOA48_000084"
     CDS             complement(24648..25283)
                     /locus_tag="NOA48_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0788399.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKKSMTISNKEMA"
     gene            complement(25285..26154)
                     /locus_tag="NOA48_000085"
     CDS             complement(25285..26154)
                     /locus_tag="NOA48_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCI0788400.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYISMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(26177..26584)
                     /locus_tag="NOA48_000086"
     CDS             complement(26177..26584)
                     /locus_tag="NOA48_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0788401.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELYENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRSD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(26603..27775)
                     /locus_tag="NOA48_000087"
     CDS             complement(26603..27775)
                     /locus_tag="NOA48_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0788402.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAILWMATMTTVFGY
                     FAGLRGIVLILVGGFIGACFAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVA
                     KLFGEKGENKKSIEDIKLPTHFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGD
                     QNYIMFAFLQAIQFVVGVYVLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFP
                     YSPNAVILGFITTTIGTIIAMFTLPMFGLAMILSGMLTNFFAGGTAGIFGNAVGGRRG
                     AIIGGIAHGFFITLLPALLVTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(27802..28104)
                     /locus_tag="NOA48_000088"
     CDS             complement(27802..28104)
                     /locus_tag="NOA48_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0788403.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(28129..30215)
                     /locus_tag="NOA48_000089"
                     /pseudo
     CDS             complement(28129..30215)
                     /locus_tag="NOA48_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(30704..31469)
                     /locus_tag="NOA48_000090"
                     /pseudo
     CDS             complement(30704..31469)
                     /locus_tag="NOA48_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
     gene            complement(31580..32449)
                     /gene="mdcB"
                     /locus_tag="NOA48_000091"
                     /pseudo
     CDS             complement(31580..32449)
                     /gene="mdcB"
                     /locus_tag="NOA48_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(32474..33558)
                     /locus_tag="NOA48_000092"
                     /pseudo
     CDS             complement(32474..33558)
                     /locus_tag="NOA48_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            complement(33582..34175)
                     /locus_tag="NOA48_000093"
     CDS             complement(33582..34175)
                     /locus_tag="NOA48_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCI0788404.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWATEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(34179..35855)
                     /gene="mdcD"
                     /locus_tag="NOA48_000094"
     CDS             complement(34179..35855)
                     /gene="mdcD"
                     /locus_tag="NOA48_000094"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCI0788405.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDFIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEETIVISIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKFRQAGYPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(35845..36144)
                     /locus_tag="NOA48_000095"
     CDS             complement(35845..36144)
                     /locus_tag="NOA48_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCI0788406.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(36246..37892)
                     /gene="mdcA"
                     /locus_tag="NOA48_000096"
     CDS             complement(36246..37892)
                     /gene="mdcA"
                     /locus_tag="NOA48_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCI0788407.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVVADKADKDGNL
                     YTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADEPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALVVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLREAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(37899..38810)
                     /locus_tag="NOA48_000097"
     CDS             complement(37899..38810)
                     /locus_tag="NOA48_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0788408.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLTFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEMVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            38930..39220
                     /locus_tag="NOA48_000098"
     CDS             38930..39220
                     /locus_tag="NOA48_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0788409.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLYTLEEGINYCLRSMRRSLLPSYCI"
     gene            39172..39786
                     /locus_tag="NOA48_000099"
     CDS             39172..39786
                     /locus_tag="NOA48_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI0788410.1"
                     /translation="MSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQH
                     HLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPIL
                     MLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKN
                     DPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK"
     gene            complement(39973..40335)
                     /locus_tag="NOA48_000100"
     CDS             complement(39973..40335)
                     /locus_tag="NOA48_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCI0788411.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            40681..42118
                     /locus_tag="NOA48_000101"
                     /pseudo
     CDS             40681..42118
                     /locus_tag="NOA48_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(42125..44677)
                     /locus_tag="NOA48_000102"
                     /pseudo
     CDS             complement(42125..44677)
                     /locus_tag="NOA48_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(44791..46122)
                     /locus_tag="NOA48_000103"
     CDS             complement(44791..46122)
                     /locus_tag="NOA48_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0788412.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYSLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELAAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQMIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCTHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(46088..47566)
                     /locus_tag="NOA48_000104"
     CDS             complement(46088..47566)
                     /locus_tag="NOA48_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0788413.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPKKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(47871..49706)
                     /gene="tdc"
                     /locus_tag="NOA48_000105"
     CDS             complement(47871..49706)
                     /gene="tdc"
                     /locus_tag="NOA48_000105"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0788414.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTTHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHMTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            50175..51602
                     /locus_tag="NOA48_000106"
     CDS             50175..51602
                     /locus_tag="NOA48_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788415.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQVSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRLTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERTDRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(51694..52059)
                     /locus_tag="NOA48_000107"
     CDS             complement(51694..52059)
                     /locus_tag="NOA48_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0788416.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(52056..52421)
                     /locus_tag="NOA48_000108"
     CDS             complement(52056..52421)
                     /locus_tag="NOA48_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0788417.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(52613..52860)
                     /locus_tag="NOA48_000109"
                     /pseudo
     CDS             complement(52613..52860)
                     /locus_tag="NOA48_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52859..52987
                     /locus_tag="NOA48_000110"
     CDS             52859..52987
                     /locus_tag="NOA48_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCI0788418.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            53044..54738
                     /locus_tag="NOA48_000111"
     CDS             53044..54738
                     /locus_tag="NOA48_000111"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCI0788419.1"
                     /translation="MRKSKSIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKSNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            54742..54861
                     /locus_tag="NOA48_000112"
                     /pseudo
     CDS             54742..54861
                     /locus_tag="NOA48_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            54865..54984
                     /locus_tag="NOA48_000113"
                     /pseudo
     CDS             54865..54984
                     /locus_tag="NOA48_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            55512..56645
                     /locus_tag="NOA48_000114"
     CDS             55512..56645
                     /locus_tag="NOA48_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCI0788420.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNVLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            56676..56966
                     /locus_tag="NOA48_000115"
     CDS             56676..56966
                     /locus_tag="NOA48_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCI0788421.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKQ"
     gene            complement(57026..57485)
                     /locus_tag="NOA48_000116"
                     /pseudo
     CDS             complement(57026..57485)
                     /locus_tag="NOA48_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(57615..58868)
                     /locus_tag="NOA48_000117"
     CDS             complement(57615..58868)
                     /locus_tag="NOA48_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0788422.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(58897..59214)
                     /locus_tag="NOA48_000118"
     CDS             complement(58897..59214)
                     /locus_tag="NOA48_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0788423.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(59240..59560)
                     /locus_tag="NOA48_000119"
     CDS             complement(59240..59560)
                     /locus_tag="NOA48_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0788424.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(60025..61440)
                     /locus_tag="NOA48_000120"
     CDS             complement(60025..61440)
                     /locus_tag="NOA48_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0788425.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREHEERYMDEKGIVQDDYRIEF
                     IGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(61456..62772)
                     /locus_tag="NOA48_000121"
     CDS             complement(61456..62772)
                     /locus_tag="NOA48_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0788426.1"
                     /translation="MRGSGMSFMDKLAKVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISYLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(62922..63620)
                     /locus_tag="NOA48_000122"
     CDS             complement(62922..63620)
                     /locus_tag="NOA48_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCI0788427.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(63909..64869)
                     /locus_tag="NOA48_000123"
                     /pseudo
     CDS             complement(63909..64869)
                     /locus_tag="NOA48_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(64983..65816)
                     /gene="msrA"
                     /locus_tag="NOA48_000124"
     CDS             complement(64983..65816)
                     /gene="msrA"
                     /locus_tag="NOA48_000124"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0788428.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(66050..66793)
                     /gene="truA"
                     /locus_tag="NOA48_000125"
     CDS             complement(66050..66793)
                     /gene="truA"
                     /locus_tag="NOA48_000125"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0788429.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(66984..67619)
                     /locus_tag="NOA48_000126"
     CDS             complement(66984..67619)
                     /locus_tag="NOA48_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0788430.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(67766..69007)
                     /gene="sstT"
                     /locus_tag="NOA48_000127"
     CDS             complement(67766..69007)
                     /gene="sstT"
                     /locus_tag="NOA48_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCI0788431.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            complement(69328..70005)
                     /locus_tag="NOA48_000128"
     CDS             complement(69328..70005)
                     /locus_tag="NOA48_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI0788432.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKNVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(70256..70798)
                     /locus_tag="NOA48_000129"
     CDS             complement(70256..70798)
                     /locus_tag="NOA48_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0788433.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(70803..71030)
                     /locus_tag="NOA48_000130"
     CDS             complement(70803..71030)
                     /locus_tag="NOA48_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0788434.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(71109..72989)
                     /locus_tag="NOA48_000131"
     CDS             complement(71109..72989)
                     /locus_tag="NOA48_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0788435.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            73275..73610
                     /locus_tag="NOA48_000132"
     CDS             73275..73610
                     /locus_tag="NOA48_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0788436.1"
                     /translation="MGIEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
BASE COUNT        21784 a        15598 c        12352 g        24015 t
ORIGIN      
        1 catgtcctat ccttattaga atacaaagat attgttttcc tgacaggtac cgtttcataa
       61 gcacaccaaa taaactttgt ttattggcta ttcgacttac tgattagata ccagctacac
      121 tcacaaaaca taccccattc ttctaggtct tatttatttt ccacttaact atagcaagac
      181 acattttggt tgtcaaactt tagtatgttt tatagattta caccattaat gaatagacac
      241 ctaccgcgat aattgctccg atcattggac ctgcgattgg tacccatgaa tatgcccaat
      301 ctgaagttcc tttattagct attggcaata ccgcatgtgc taatcgagga ccaaagtccc
      361 gagcagggtt gattgcatat cctgttggcc ctcctaatga aagaccgatg gctaagatca
      421 atccacctac agcgaatacg ttcgttccag gtgcaaattc gttttgtcca aaagctagca
      481 acccaagaac taatacaaat gtaccaatta attctgtgat cacatttgct ggataattcc
      541 gtatagcagg acctgttgca aacgttccta aaatcgcgct ttcatctttc gttgcattcc
      601 aatgtggcaa ataagaaagc caaacaagaa tggcccctgc aaaagctcct aaaacttgcg
      661 caatgatgaa aggaacgaca agattccaac taattgcccc tgtcatcgcc atagctagag
      721 agactgcagg attcaaatga gctgggccca tgaatccaga aatatagaca gccattgtta
      781 cagcgagtcc ccaaccaaat gcgatgacaa tccagccaga agcctgtgct ttacttttgt
      841 ttaaattcac agccgcacac acaccatctc caagcaaaac taggatcagt gtcccaataa
      901 actcccccat gatttgagtc atatcactgt tcatttattt ctcccccttt agttcccgca
      961 gatctgattc tgcaatcaat gcttctaaac gtttagtctg ttgcgccttc tcctcttctg
     1021 tccattcaaa atatccagca attgcatcga tcacaggttg cttgatctca tcaagctgat
     1081 ctcgttcaaa caacagatga tttgtacgac gaatgagata atcgcctggg gccaaaacca
     1141 tttcttcttc taaaccataa cgtaaccgag ctgactcagc gagactcaaa ccaggataag
     1201 gtgccatttc ttttgctaat tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga
     1261 tataagtagc atcttcttcc tctaaaccgg ctgctactcc ttcttttgct aattctgtca
     1321 ctgtttcttc taatttagtt ggatcgaagt ttccacctga aatctgatat tttttagagt
     1381 cgatttcttt cgtctctatt ccgtattctt cttttaataa ttggcgtatc aatcgcaaag
     1441 ctccttctgc catcttacgg taatcggtga ttttcccacc agataaagtc agcaaaccat
     1501 ctggttctct ttctaaagaa ctacctctgg aaatcgtaga aggtgctttt tcatcacggc
     1561 tgttttccaa atggttcaac acgtcttcta cttcagcacg agaaactttg ttttccttat
     1621 attcacttac tgtatcgaca actttattga agctcttgtc tgaaatcgat ccattatctc
     1681 caccattgta atcagaacca gaattaccaa tcaacagtgg acgaagtcct gcccagcttg
     1741 cttcgatatc attcaatgtg atatttgctt ctggatagcg atgattgatc acatccaata
     1801 gataatctac atcttcttgt gtgactttcg gatccgtaaa atctccttgg taatccgtat
     1861 ctgtcgtacc aaagtaagtc ttgttttctc ttggaatagc aaaaaccatc cgcccatctt
     1921 gctttcctgt atcgaagtat gtgggttgcg gtacaggcag ttttttcgca tctacaacta
     1981 aatggatccc tttagttgga cgcattttag gagagactgg acgcgtaaaa ttcaagtttc
     2041 gtactttatc tacccaagga ccactcgtat tgatcactaa ttttgctttg atttcgatca
     2101 cttcatctgt cagcaggtca cgagctttga cgccaacgat ttgatcgcca tcatataaaa
     2161 agccaaccgc tttcatttta cttactagat aagccccatc ttcggcagcc tttttgatat
     2221 tatcaatcac taaacgggca tcattgttgc ggaaatctag atagacaccc gcgcctttta
     2281 gcccttcttt tttcaaaaac ggttctcttt ccaatacttc ttctggtgtc agcgtataat
     2341 tctcatattt ggttcctgtc acatttgcca gtttgtcata aaggtccatt gctactttga
     2401 ccgagaacat attgaaggtt gttgctcctt cgccctcata gattggcaaa agcattggat
     2461 ctggttttgg gatgtgtggg gcaatacttt gtacgactgc acgttcacca actgtgtcag
     2521 ctactacttc cacatcaaat gtcttcagat aacgaatacc gccatgaaca agtttggtcg
     2581 agcgagagga agtcccttct gcaaaatcct gcatttcgat caatcctgtt ttgattcctg
     2641 atgctgctga ctggactgcc acaccggcac cagtgattcc gccaccgatg atcaacagat
     2701 ccaattcttc ttgctgcatt ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat
     2761 ggatttcctc cttattcaaa tgcttgggta gcttttactg cttttttcca accgttgtaa
     2821 agtttttctc ggcgctcttc ctccatttga acttcaaata gcttgccagc ttcataaaat
     2881 tcgcggatct cgtctgtatc tttccaataa ccgacagcta atcctgctaa aaatgctgcc
     2941 cctagcgccg ttgtttccaa gttttctgct cgttggatcg gtacattcaa gatatctgtt
     3001 tggaattgca tcagatattc attgtttgct gcaccgccat ctactttcaa tacaggaatc
     3061 ttgattccag tgtcatcttg catcgtatcg atgatatctc tcacttgata agcaatcgac
     3121 tgtaaagtag ctttaatgat atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc
     3181 cctcgtgctg cctgatccca ataaggagca cctagcccaa cgaatgcagg aacaacataa
     3241 acctcatctt cgcttgtaga gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac
     3301 atttgaagtc catctctcag ccattgaatc gaagaaccag ccacaaaaat acttccttct
     3361 aaagcatagt aaacctttcc atttatgccg taaccaattg tcgtcaataa attatttttg
     3421 gataattgcg gtttttcacc ggtattcatg acaataaatg aacctgtacc ataagtattc
     3481 ttgaccatgc ctggttcgaa tgccatttgt ccgaataatg cggcttgctg gtctcctgcc
     3541 atccctgaaa ttggtgcttc gcttccataa aaatgataac cttgcgtata accataaact
     3601 tctgagttag aagtgacttt tggtaacatc actcgaggaa tatttagtaa atctaaaatc
     3661 tcctgatccc aatctagctg atggatattg aacaacatcg tccgactggc attcgagtaa
     3721 tcagtaacat gtgcttgtcc atcggtcagt ttccatacta accaagaatc gatcgttcca
     3781 aacatcaatt cgcctttttc agctcgttct tgcgcgcctt ctacatgatc aagaatccag
     3841 cgtatcttcg ttgctgagaa ataggcatcg atcactaacc ctgttttttc gtggaaaaat
     3901 tcttgatagc cttcattttt taagttatct gcaattccag ctgactgtct ggattgccaa
     3961 acaactgcat gatagattgg acgtcctgta tctttttccc atattactgt tgtttcacgc
     4021 tggttcgtta tgccaatccc agcaatctga tttggtttga tccctgattc gatgaacgct
     4081 ccggcaataa ctgactgtac agaattccag atttcatttg catcatgttc cacccaactt
     4141 tcttgcggga aatattgcgt gaactctttt tgagaactgc cgatgtgtct tcctttcttg
     4201 tcaaagataa ttgctcgtga gctagttgta ccttggtcaa tcgccatgat atacgttgat
     4261 tctgtcattg tgattccctc cattatatgc aaacgctttc tttaactact cttatcatac
     4321 tactgtttta aaaaaagaaa ctgtcaaaat tttattcttt ttttcttttt ttgacagttt
     4381 tttattatga agctattttt taatcaattc ttttcttttt tcagcgtctc tattcttctt
     4441 ttcaatcgaa taatgtcgta aggtgacgca aattctgaca gataatattc acactgtttt
     4501 ttgtttctct ggcaaaatgt gatcaccaaa tcatattctt taccttcttc ataacttcca
     4561 atctcaatac cgccgattcc cctcagttct ctgatcagat attgttgaaa agcaatacga
     4621 taaatcggca gactttctaa atcgattcca atcactactg gttttgcaat ataaaaatcg
     4681 atcatcaaaa gaacattggc atactggatc atcaggtaac taagctcact atcttcagct
     4741 cttttcctcg gcaattgctg caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag
     4801 gaatgcccga gcattttctg ctgctgttcc aaaagccgat cacgctcata gacttcgatc
     4861 tttccaacaa agaaaaacca ttcattgttg atctgggaaa tttggtagcc tactgccttt
     4921 tcttctttga ttttcaaacg acgaggacga taatgccata acatcgtttc ccgaatgtaa
     4981 gtatctaaaa cagcggttgg taactttttg ctccgtgtca aatcatactg ataaaatatt
     5041 tcttcgtcta ctatcgaaaa agaaacaaaa aagctgtaaa acatcattgt ttcgtataca
     5101 ttcagttctg ctgctgttcg actaagatgc atcacgatga ttggatcgat tgcttgataa
     5161 agccggtccg actgatagag taatttcttt tctttcaaag ttgcgtacgt acttttttca
     5221 ttcaatagtc tttttttcgt aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc
     5281 gtaaacgttg tttctaatac acggtccaat cctagaatga acggtctttt ttctggtgta
     5341 ttttgcaaaa aaagcggtcg ctgatcttcc gggatatatt ggaatagttc ataataaaaa
     5401 tatcgtatct gtagctcttc tccgtataat tgaccgtttt tgatttgtaa tccaaattcc
     5461 tctaagagct ggttcaattc tttgatcttt cgaaaaacag aagactcact gatattaaac
     5521 gctgtcgcta atcgaacgat ggatacttgc tgatgttcta ataaatagac gagcatctta
     5581 aacttcaagc tttcctgcaa taaaaacaat agaatttttt ccaaacttac atcttcgtcc
     5641 aacacaagca gcgcctgata ctcatttcgc tgtacttcta cttttttttc catcattcgg
     5701 ccaatcaatt caatatcttc caaatattga tcaaacgagg cttttgacag ttggacatgc
     5761 tctctcaaac cattgataga ggctgttccc ccttgcagaa caaggtttcg caaaatcagg
     5821 atctgtaact gctcttttct ttctaataat gcttcaatct tcataggcag tattcgccac
     5881 ctttgaccac accatatctg gcacacggta ttctggctgg aaaaatagct catgttcttc
     5941 taactgttca aacgtccatc cttcttctac tgcaattgtc agttggtcaa gaaggtggaa
     6001 catctctttt ttgctttgga gctgtgctcc aagaatcttt ttttcagaat caaatagaaa
     6061 tttgagttta actttgcttt gatttattgc tgtaagcttg tagtctacgt atcctgtttc
     6121 aattttttgg ggataaaaaa tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata
     6181 gccaaaccac tgattgccga ctggacgata ggttccctga tcctttgtct gtgagccact
     6241 aattgtcttg ctgacatttc gtgctgtacg gacagcgtta tttactagag aaacatacat
     6301 tttttcattt gttggacgaa aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt
     6361 ttgagacgtt tgcaagtagt catctaccca gatcgttcca tcatcattca atgttaattg
     6421 ttcttcccac atctgattgt cgggacgaga atgattagcc agcaaaacaa gatcatagtt
     6481 ctcctttctt ttttccgtct ctacaatagc ggtttcattt tcggtcaaag acacaacttg
     6541 ttcttctaaa aaaagtgaaa gcccttgatt tttcatttcc tttactaacg gttctgtcat
     6601 ttcaggatct agataacgaa aaagaattga ctttcggctt tcgtaaagat ggatttgttt
     6661 ttttcttgat gccaaccctt cagctatttc gattcctgct tgtcctgcac caataattgc
     6721 aattttcttt gcattcatga tcttttgctg aagagccgtt acgttttgta tctttttaac
     6781 tgggtgaata agcgttgatt ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc
     6841 tagaatcaaa cgatcaaaat ccaatttttt tcctcctgct aaaacgactt ttttttcttt
     6901 caatcctatt actgtctttt ctgtgtaaac atggattcga tagcggtcag tcagttcttc
     6961 tttcgtgatc caagaaagtt gtttttcact ggtaaccttt ccttttaata tcaaattgaa
     7021 cccgctggga atccatccta acttcgattg cttttcaatc aaatatattt cacttgttgg
     7081 catcaattgg cgaagataaa tagccgcatg aatccctgca aacgacccgc cgacaattac
     7141 aatgttcatc tgcattcctc tttcttataa ggtgttctac tgctaacttc tcaatcagaa
     7201 aacacagtat tcataactcg ctttcaacct tatgatacat agcgatgcag cagaatcaac
     7261 cctctccatc ataccgtgtt ctaggtctgc ttctcaataa tgtactagtg gacctaattg
     7321 aagagtatca tttctgaaga gatgtttcaa aaaatgtact cttataaaag aaaaaaactc
     7381 gccttttacg tacctctgtc caaataggaa acagaaaaga acgaaaagac gagttttagc
     7441 gtgtgtaatg taatagttag aatagacaca tcatttattt ttaattcttt aatgcttcaa
     7501 caactgcttc gcctaattga tgagcagatt gaggattttg ccctgtaaga agccgcccat
     7561 caatttgaac cacttctgaa aaagctgctc cagactgata gtttgctcct ttttctttca
     7621 aagcatcttc tgctaagaat ggtacttcat tcgttgtacc atttgcttcc tcttcttcat
     7681 tactgaaccc agtcactgta cgtccagcta aaatagattt tccagactca tctgtaactg
     7741 gcaacaatcc tacaacaccg tgacaaacag ctgagaccag cccttcattt cgatagattt
     7801 gtgaagcgac tttcccaaga tctattgctt ctggaaaatc ccacattgtt ccgtggccac
     7861 cagcataata aaccgctgca taatcatttg catccacatc atcaggacgt aaggtatttc
     7921 ccaaggcccg atttctgaaa tcttcatctt cataataggc ccaatcgatt tcatccatat
     7981 tcaaaacact ttgcggttct aaaggtacat atccgccttt aggactgaca aaatctgcat
     8041 cgatcccatt ttttactaat acatcataaa aatgagtcag ttcacttaac cacaaacctg
     8101 taggacgctc gatcttttcg tacttttcta catttgttaa tacgatcaat actttcattt
     8161 tcccatcctc tttctataaa aattgcgtta ttgataacgt gctttcaaga aattatataa
     8221 tgggcttggc aaataaagct ctttatatgc ttcttcaaaa ggtttcgtta caaattcatc
     8281 ctcacggttt tccaataatt tctctgccca gtcaggatcg acgatcattt gctgtccaat
     8341 tgctgcaagt tctgcatatt tcaatacctg ctctacatct tcgcgattgc ggatcccacc
     8401 gacaccaact aaagggatct ttccttgaat cgtgttatgg accacttcaa gaatcgattt
     8461 atcgttgtat ttatcagaac gagctattcg atcatacata tttaatgaaa catgcagata
     8521 atctagtttt gactcacgta atcgttcaag aagccagatc gtgtcttcaa aacggatacc
     8581 tggtgtttca tattcttctg gtgagaaacg ataccctacg atgaatggtt ttttagcata
     8641 ttgttcaacc gctgagaaaa ccgttgttaa taattcttca ataaaacgat aacgattttc
     8701 caagctaccg ccccattgat cctctcgtct attcgaatgc ggagagaaaa attgttggat
     8761 caaatacgta tttgctccat gcaactcgat tccatcaaat cctgattcaa tcgctctacg
     8821 tgtggctttg ccaaatgctt ggattgtttc aacgatttct tcttcactca ttgctcgtgg
     8881 tgtttccgca tcaggacgtt ttgctgcaac tgcacttgca gatacaggct gttctccaga
     8941 taaagttgct cgacttgtca ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc
     9001 ttctccttgg attgctttcg ctagctcact taatcgagga atcatttcat catgagcgat
     9061 gctgagttca cctggccagc cttttccgat atcttggaca tttgcagcac cagtaataac
     9121 agcaccaaga cctttagaac gttgtttata ataagtgatc tcatcttcgg tgatcactcc
     9181 attgaaaaag ctgagttgtg tcgtcatagg cgacagcatc aatcggttct tcaattgaac
     9241 tcctgaaggt aaagtaattg attgatcaaa ttgtgacatt gtcattcctc ccataattcg
     9301 ctctgattaa cctatcgaga atcatctatc attaaaccac tcgattagtt gtacatgcaa
     9361 ctaatttgct taaaaaattt tatttttttt gtaacttatc tgttgcatca ttcattgtct
     9421 gggctaattc tttacttgct tcatttccca aaactgcttt gtatgactga tgaagttctt
     9481 cccagctacc atcgacttcc ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg
     9541 acaagcgacc ttcgctaact gttttgacgt atcctttata ttctaatttt tcaacaaaac
     9601 gagcaatcgt tgatggggcg gaatagagca tttgtgcaat atctttttgt ggtattccat
     9661 ctttttcttt taatatcaat aaaataaaac cataagttgg tgccagacct gtccttctaa
     9721 acgcttcatc agctaattta ttcaacatgc gatctagctt tttcacgcta aagaaaagac
     9781 attcatctaa cgctttttca attggctttt ccatttcatc ccctccattg gcgtacatat
     9841 catagtatga tttttatttt ttgtcaaaaa acacggaata atgtccgcct cctctgtcta
     9901 gatttgaaaa aaagaagtag ccatcttcaa agaatttcgg cttgttttcg acaaaactcc
     9961 ttctggaaca ccgtgaatca gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa
    10021 aattttgtga aaatggcttt ccacattttt gcataaattt ggcttaatac cgaaaaactg
    10081 gcttttgaac accgtttata tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag
    10141 aacagccaaa caaaaatagt tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc
    10201 agctgattgt acaccgttta ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa
    10261 ggagcaattt caaaaaacag cttctcatgt tttatgacta tggtgacttg tgatcgagga
    10321 gttggcagga gaatactgtt tattcgtaaa gaaggggctg tgacaagact tttgtcacag
    10381 tcccttattt ccttttatta taggatttcg ccatttgatt ggatgacttg tctgtaccaa
    10441 tcaaatgatt ttttctttaa ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca
    10501 tagatatatc cataacgttt tgacatttgt gaagtagaag cgctgacgat atcaatgcag
    10561 ccccacgacg tataaccaaa taaatctact ccatctttga tagcttcctt catctgctca
    10621 atatgctgct tcaaatagtc aatgcggtaa tcgtcttgaa cggttccatc ttcttctact
    10681 ttgtctatag ctccgagtcc gttttcagct atgaacagtg gtttttgata cctatcatat
    10741 aattgattca aagcaattct caaaccctta ggatcaatct gccagcccca ttcacttgat
    10801 ggaagatacg gatttttaat tcctccagtt attaagtttc cttggacccc ttcccaattt
    10861 tctggatgag cactgactgc actagacatg tagtagctaa aagaaacaaa atcaacaggg
    10921 taggctgcta agatttcttc atcacctact tctattttta agttgacacc tttttcttca
    10981 aacattcgtt gcgtatacgc tggataatat cctcttgctt gaacatcact aaagaacaaa
    11041 gaagttcttt gctgctcaat tgttttttga atatcatccg gatcacaaga atacggaaca
    11101 agaagctgat agctgatcat acaaccgact tgtgaacctt tgataatttc atgacaagct
    11161 tttgtagcta aagcacttgc tataaactga tggtgtgcac cttggtattt cgcttgttcc
    11221 aaatggggat ggttttcttc aattactcct acgctaacaa aagggtgatg ttttacacag
    11281 ttgatctcat tgaaagtcat ccaatatttt actttatttt tatagcgttt gaatactgtt
    11341 tcagcgaaac gaacgtaaaa ctgaataagc tttcgattag gccatccacc atattctgta
    11401 accaaatata acggcatttc ataatgggaa agagaaacga ctggctcaat cccatatttt
    11461 agacattcgt caaacacttg atcataaaaa aataatcccg cttcattggg tgtttcttca
    11521 tcaccatgag gaaaaattct tgtccatgcg atagacatcc gatagcattt aaaacccatt
    11581 tcagcaaata aacggatgtc ttctttaaag tgatgataga aatcatttcc gtgtctttta
    11641 ggataataat acttgctgtt gggatcctgc gccgctttta cttgctgatg cgtcatcata
    11701 tgccattgat ctgtccattt ttctttaggt aaatcgctgt cgaatgtata cacatcagac
    11761 acagataatc ctttttcatc tacatcccat gcaccttcac attgattggc cgctgtcgct
    11821 ccgccccata aaaatccttc tggaaatttt ttcatatcga tccccctaaa cttgctagtt
    11881 ttcttgtttg attatttttc ttatgactag taatgatatt tttgaatcta ctactatttg
    11941 taacaataac cattgtggtc ggatcatatc cctctttgat taattcttgc aaatctactt
    12001 ccatcaataa atcgccttta cgtacttttt ttccatcaga tactgcactt tgaaagtatt
    12061 tgccatttaa attcactgta tcaataccga tatggatcag tatctctgct ccttcttcac
    12121 tgactacccc aattgcatgt ttcgttggaa aaactgttga aacttccccg tttacagaac
    12181 tgtagatttt tccgtccgtt ggaatgatcg caaacccttc tcctaaagat ccactagcaa
    12241 atgttggatc gtttacttca gataaatcaa ttatttcacc tgctgcagga gtacttaaca
    12301 ctatatcctt tgaggattct tcttcgattt catccttgta gccgaaaaga aaagttagca
    12361 tacaggaact gatcatcgct aagaaataac tagcaactag ccaaacaaat ccttcaccaa
    12421 tataaatcgg gaaagacaaa atacttcttg tagcaactgc caaagcaccg gctcctgcgg
    12481 caccagctac tccaccaaat atagctccac atatacaagc aatgtaaaat ggtcgtttat
    12541 atttaagagt cacaccataa acagcaggtt cagtgattcc aaataatgct gtgataaatg
    12601 cagataaaga taaacttttt actttcttat ttttcgtttt caaaaatacc ccaagtactg
    12661 ctcctgcttg cgcagctacg gcagtcatac atgctggacc tagcgtatca cgaccgtaga
    12721 aagaaagatt gttggtcatt actggtacaa gtccccaatg taacccaaaa atcactaaca
    12781 cttgccaaaa tccgccgata acagcaccag ataaaacagg gctaaagtta taaacagcta
    12841 aatatccagc tgcaatcagc tgacttgcat aatctgcaat tggacctaca actaataaaa
    12901 taattgggac catcacgatg atacaaatga atggtgtcaa taaatttcga atactttcgt
    12961 gcaagctttt gcgaatctta ggctcaatat aagaaagaac ccatacagct aaaattgctg
    13021 gaataaccgt acttgtatac cttgctagaa tcacgggcat ccctagaaat cgcaaggtta
    13081 tgctatcact atatgcactg acaatcgtag gataaacgag agctgctgca ataaccatag
    13141 cgatgaaacg atctgtattg aacttttttg cagcagtata tgccaaaaat ataggcaaga
    13201 aatagaaaaa tgcatcagct gctgcattca aaatgatata agttcctgat tcagtagtta
    13261 ataaattcaa actcgtacat aaggcgagta ctcctttgat caaaccactt cctgccaaga
    13321 cgcctaaagt cggggcaaaa acagcggcga tcatgtctat aaaagagttt aaaatgcctt
    13381 ttttctcagt tcctctcttt ccactagatg catcatcttc tagtttcatt tgtttggata
    13441 atacgtcata cacttcattt actgcatttc ctactacgac ttgaaacatt cctccagctt
    13501 cgactacagt gatcacacct tctagttgct ctaccttctc cttatctgcc ttcttattat
    13561 cttttagggt aaagcgtaac cttgttgcac aatggtaaac attgctgaca ttttcttcgc
    13621 ctccgacaaa tcggacaata tctttcgcta attgtgaata gtccattttt acttccccct
    13681 tgttaattaa tgccgtagca atccttctta caagataagt atagttctta gaaaacggtt
    13741 tctccattca attagtaccc cttctaatag cgaacgaaac tgtacaatag tgtgtatggt
    13801 ttacttagcc gagcaaatca ctcactgctt gaaagaaaac aagtatatcg tttctcttat
    13861 agtcaaagga gacaaaaaaa acacgcttga tcttcctttg ctgatgtata agtggtatct
    13921 caagctgata ctctgtgatt tttgtttcta cttggctttt gataagacag cacaacaaag
    13981 tctcggcatt taacggaagc ataactaggt cagaactagg agagattagt tgctgaatgg
    14041 aatctatctt tttatggatt tttatttgat tttcttcttt gtagtaatga tcaagcagtt
    14101 ttgttttctt tttttcttca actatggtca gcttttcacg caaaatctga taaatctccc
    14161 aagattcaaa ctcatctaga acactaggta gataaatcaa atcatcccac tcaaaaataa
    14221 gctcttgctc agtagtcaaa attgcatcat attccgttat tttgtttgat tgatttttga
    14281 aaagatacac tggttctatc cggcattctt tgatccacat gttcatactt tgttgaatct
    14341 gtttttttag tgtattcaaa atactaattg gctggttact aacaatcagt atctcccctt
    14401 gttttcgaaa aggattcaac gcttcggcaa gatacaaaac aaaataagcg ctttcagcta
    14461 aattgggacg taattgaaaa tgtattggga agaaacgccg aattaaataa atttctaaag
    14521 gataacggga gatgatcttt tgtacaaaat gattcatggt attatgtccg gcatccatcc
    14581 tcgttttcat ttgtttgata tgggttagca aaaattctgt ttcatggaac aataacgaaa
    14641 caggaagatc taaaaaacga ataatcgttt gctcaaatgc tcttagattc ttctctattt
    14701 ctttgttttt ttcatcatta atcatcaaat aatttaactc taatagtcga ttttcaattg
    14761 cttgtttttc ttgattggaa aaagaatagg gtagttctga tgataacttt tttgtgaggg
    14821 tctctaccat cggaataaat aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc
    14881 gaagaatggt caaaacgaga taccgagaaa atcgtatgaa gtcctctcct gaaacaatat
    14941 aattatatga tataagaacc tcttttaatg tcttttggac agtcggcatg atattggaaa
    15001 aaattgtact gatttgttga ggaaaccttg cgtgttggat caccgtttct gttccaacaa
    15061 gagataagaa aattcttttt gaattttctt cagcaatgat ttttagtcct tttgtcgacg
    15121 aaacttccag ttctaattta ggattgcgct cgatccaacg caaaatcgtt tttatttgta
    15181 atgatacggc tgtttttgaa agaaagaaaa tgtctgctat cttttgcata ctgacatacc
    15241 ctttttgaaa caataagtac gtcacaatag ttgaagctcg gaaatccatg ctggaataga
    15301 ttttatgttt cgtcacctct tgtatgattt gctgtttagt ttcagattca attgattcta
    15361 aaaaataacc tgaacgttta tttgactgga taatgatttt cttctcgtag atagcaagca
    15421 tatttttgat ttcagtttgg atcgttttct tgttggtacc taaagcttca gctaattctt
    15481 cgcttgttat ccaatgattc ttatttctta atactacaag aatttggagt tgtcgtttat
    15541 ttaagtccat ttgcttacac ctcctctttg ttataaacat acaggaaaaa cctctcaaat
    15601 gacaatagtc acttgcagag gtttaaaaat catttgaaga aagatctata ttcaaggttt
    15661 ttaccattag actggataat ttgtttataa tattcaaaac tatctttttt caatctccta
    15721 aagcttccgc tcccatcatt ttgtctatcc acataaataa agccatatcg cttcctcatt
    15781 tcccctgttc ctgccgatac gatatcgatt ggtccccacc ataagtaacc aatgatttgg
    15841 caaccatctt ttattgcctc agcaatttcc tgaagatgta tttttagata ctcacaacgt
    15901 tttggatcgt ggattcgatt caattcatct ggtgcttcat ctagtccaat gccattttca
    15961 actatgaata atggtaattc ataacggtct gtcaattcat tcatgacata acgaaaccct
    16021 agaggatcaa ttggccaact ccaaggttcg ggagattttt ccttcaaaaa gggattatcg
    16081 aaaccatttg ctccgccagt atctacgcgc atttctgctt cttttttata gacagcgcta
    16141 cgataataac taaatgcaat ataatctgcc gtgttagctt gcaagcactg ttcgtctcca
    16201 tctaacatta ctggtgcaca gtcttcttcc ttccatgtcc tgtaaatata agctggataa
    16261 tgccctcggc acatgacatc ggagaaaaac catgaattgc gtttaaattg cagtgaacca
    16321 aatacattct ctggatcaca gtcatatgca taagtcgcta atgcagaaaa gctacacata
    16381 atacccatct tagcatttgg atcgattttc tttaataatt gagtagcacg ggcgttcgct
    16441 agaaacatat gatgacaggc ttgataaatc actttttttg ttagtgtagc aatgggttca
    16501 agtttatctc tagcagggaa tgtaaccaat ccagcagctg cataaggcat acgaaaagca
    16561 ttattgatct cattaaaggt catccaatat ttcactttcc cttggtagcg ttcaaagacg
    16621 gtctgcgcat aaaattcaaa aaagtcgatt aattttcgat tttgccaccc cccatactct
    16681 cctaccaatg ctaagggggt ttcataatga ctaagagtaa ttactggctc gatatcatat
    16741 cgatttaatg tattgattag tctgtcataa aatacgagac cagcctcatt tggcttctgt
    16801 tcgtctcctc ttggaaatat tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct
    16861 aactccttca gtaaacgaat atcctcttca aatcgatgat aaaaatcaat cgcttcatga
    16921 gaaagataat ggagtgattc gtctaaagca atctcccaaa tctttttttc ttcattccac
    16981 tgaatactag gatgctggtt catgatcccg ataagcgtat ctgtcacatt aggtaatttg
    17041 ccgtcttcca accatgcacc ttcacattga ttagcagcta ctgctccgcc ccataaaaaa
    17101 ttttctggaa atatttcctg atccataact atctctcctc gctatcaaca atttcttact
    17161 tgaagtatag ctcgattcat caaaacaaga tattctaact atttcggcag aagagaagaa
    17221 aaaaattgaa tgctactctt catttttaat atttatatat aacaaataca taagacgatc
    17281 cccgaaagaa aacactcgtt aaccatctaa gcaaacgatt tattttactt ccaacacaaa
    17341 tgcttcataa ggtcgtaaat caactttgcc gtctggtaac tgtttcagag gataatttga
    17401 cacaataacc cttaaagctt cacgtggaat agtgaacgtc tgcttttcac tggacatatt
    17461 acaaataacg agccattgct ggtcttcata tatgcgagaa taggcaaaga catgctcagg
    17521 cgtcttttcc actaattcat agtctcccca gacgatgatg tcatgttttc tacgcaaatc
    17581 gatcaatttc ttgtacatat aaaaaacaga atcttgatct gctaacgctt cttctgcatt
    17641 gatttcttta taatttggat tgactcgaag ccatggaatt ccagtagtaa acccagcatg
    17701 ttcacgggcg ttccattgca taggcgtcct agcattgtct cttcctttcg ccttgattga
    17761 ttccaagatt tcctcttttg taaatccaga agaaatcctt tcgttataca tattgattgt
    17821 ctcaatatct tttgcttccg cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc
    17881 tccttgatag atataagggg tgcctttcat catatggagc aagatagcaa acatcttggc
    17941 actttctttt cgatacacat cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg
    18001 attattccaa aataaactat tccatccttc atcacctaaa gatgtttgcc atttggataa
    18061 tacttttttc agttcagaga tactcaaggg tttcaaatcc catttgtctt tgccttcttg
    18121 ctgatctaat cctatgtgtt cgaattggaa gaccatggat aattcatttc ttttaggatt
    18181 ggaataaagt ttagcgattt cggtagttgc tccccatgtt tcgccaacag tcatcagatt
    18241 tttgtcacca aaagttgctt gattcatttc ctgaagatac tcatgcagtt taggtccatt
    18301 acttgtgatt tctttatccg gttctttgcc aatcatatcg atcacgtcca tacgaaagcc
    18361 cccaatacct ttatcgatcc agaaattcat catttgataa atctcttggc gaacctgttt
    18421 atttttccaa ttcaaatcag gttgacgctt gctatacaag tgcagaaaat attgccccgt
    18481 tttttcatcc aactgccaag cagaaccact gaatattgag cgcaatctat taggctcttt
    18541 tccattgacc ggatcacgcc aaatataata gtcccgataa ggattttctt tatttttacg
    18601 ggcctcaatg aaccacggat gttcatcaga agtatgattc accaccagat ccatgatgat
    18661 acggatattt cttttctttg cttcttcaat cagttcttcc atttcttcca tcgtaccgaa
    18721 ttctgccatg attgcttgat aattactgat atcataccca ttgtcatcat tcggagactc
    18781 gtatactgga gaaagccaaa ttgcatcaat acctaaatac gccagataat ccaacctgga
    18841 aataatcccc cgcaaatctc caataccatc ttgatttgaa tcttgaaaac ttcttggata
    18901 gatttgataa acaactgaat ggtgccacca tttttgttcc atgattttcc tcctataaat
    18961 ggatgtttct attttttgct taatcattta ttttagtctc tctcactaaa aattgtaacg
    19021 ctttcaaata gctattgcac cttgttatcg gtaacagaat aaaacaaaaa aacagctgag
    19081 gaaattccct caactgtttt ttgaaaggat tgatttatgc agggaagaat gctgatttca
    19141 caacttcttt ataaacggtg ttcactcagc tgtcccttgg tattagctca aaaaacggca
    19201 aaatataaga aactattttt tcgttttttt ctctaatact caggccagaa cgctgatttc
    19261 acaacctctt tatttcacat tcaatatcca catgaatccc acaaatacaa agaacagacc
    19321 atacatgatt ggagatactt cttttcctct tttagctgct aacatggtaa ttggatagaa
    19381 gataaaacct aatgcaatcc catctgaaat actataagtc aaaggcatgc cgatcaagat
    19441 caagaatgaa gggatcgcaa tctctaagtt tccccattcg atttgtcgca aagattgtgc
    19501 catcaatact cctaccataa tcaatgctgg tgcagttact tgtgaagtaa caactgatag
    19561 taatggagaa aagaacaagc ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc
    19621 tgaacgtcct ccaacggcga taccagctga tgattctaca aatgcaccaa caggagaagt
    19681 accaaataag gaacccgcaa gcatagctgt tgaatcagaa gctaaagctt tccctacacg
    19741 aggcatcttg ttgtctttca tgaaacctgc ttggtttgct aatccaacta aagttcctgc
    19801 tgtatcaaag aaagtcacaa gcaagaatgt cagcactacg acccacattt gaagagaatt
    19861 gatgtcccct acatgtttta atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc
    19921 aacaatttca gaaggcattg gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc
    19981 catcccgatg aagatgccac ctggtacacg ccgaacaagc aagatagcag ttacgactaa
    20041 tccaaaaatc gtcaaccaag tagaaccaac gttgagtgat cctaatccta ctaatgtaga
    20101 ttcattcgaa acgatgatcc caccttcgct cagaccaagg aaagcgataa atagaccgat
    20161 accgccagaa atcgcatatt tcaaatctgc tgggatcgca tcaatgatca tttcccgcag
    20221 cttgaagatt gtgatcaaaa taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt
    20281 ttcccatgga atccccattc ctaaacaaac agaataagca aaaaaagcat tgatcccaag
    20341 agcaggtgcc gttccaattg gataacgggc taataccccc attaaaatac agccgatcgc
    20401 actggctaat gcagtcgcag taaacactgc tccttcatcc attccagaag cacctaatac
    20461 agttggattt acaaataaga tataagccat tgagataaat gttgtaaatc ctgccagtac
    20521 ctcacgtttt accgtggtgt tcaatttttc tatttcgaag taggaaagta ttttttcctt
    20581 catcttccat ccccctaaat ccgaacatta taaataaagt ccgttaaaat ttcgatttat
    20641 taataaaaca acgtgtttta tcatatacta aaacaaaata taagtaaaca aaaaattcgg
    20701 attttaagca aaatccgaac gtttcatctg attaaatccc tttatctcaa agttcatgaa
    20761 cattcacttt ggattacaag aatttcttta ttgtgttaat aaagtttctt cattctagtc
    20821 tcaaaaatca atagtgtgat ttgattttac catttcgttt ctgttattct ttgatgaatt
    20881 cttttgtatc gacaggattc agattattta gtccgccaaa acctgtgtcg accatttttc
    20941 cccagccttt tgtcttcttt tttcctgatt tgagattctt tgctcgaagc ttctcactat
    21001 gttttgctcg ccgatacttc aaataacctt ctaatcttcc cattagatcc actgtttttc
    21061 ctccttttta ttcaatcaga cgactcagct tttcctataa caaaataatt gccttcaggg
    21121 tccgaaaaat tgaaagtcaa gacgccattg ttgtctgtga tttctcctgg ttcttccatg
    21181 ttctcgtaga tagtctcaaa ttcgtccgta aaaaacacta aagaaggcgg tggtcctaat
    21241 acttctggtg aaaatttctg cacaaatact tttgggaata cgcctaattc taattctttt
    21301 gagatgctga gtacaatact cttaaattct tctggcaatt cgattgtttc agaaatttct
    21361 gcaccaattt tttctacaaa gaatcggcaa atcatctcta cgtcattgac ataaagcatc
    21421 acacgtgttt tttgtatcat cgtttgaccc ttctttctat ttgattttct ttcctgtcta
    21481 taaactgatt ccattatatc acgaaagcgc aaacaccttg tgtttgatac tattcaagaa
    21541 aaataaagca atagtttcta ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa
    21601 aaacggcaat gaatgccgct cttctttttt cgattctttt ataattctgc ttctgattca
    21661 tctttggtta gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc
    21721 aacgcttcga ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc
    21781 agcaccgctg cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga
    21841 cagcgacaga tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca
    21901 tcggaatctg cacctaaagg caggaatgat tcgccacctt gggcttttcc taaatgcaga
    21961 tttcctgcga tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata
    22021 ctattataga tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt
    22081 ttcagtaaag cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc
    22141 tgacgccact gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt
    22201 gcttcttttg ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg
    22261 tggttatcga taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag
    22321 aaattggtat ccactattac ttttttcata tgttcacacc tcttgattag aataattgct
    22381 tgatgaatag atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt
    22441 tgataaatcc ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga
    22501 gccaaatggc tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg
    22561 taccgatacc ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat
    22621 gatcagccat ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct
    22681 cttgatcgat actcactagg aaaaaatcgg tttctttatc ttttagctct tctgtaagtt
    22741 tttctggcgc ataagcttgt gtcaagtaat cagctaaatg cttcggtgaa ttatcttttc
    22801 caaatgtatc tgtaaatgtt tcgatactga tttgttgtag taagtctaca tctgaaggcg
    22861 tcatttttcg aatttcgtat ttattcacgg cttcttcctt tcaatagatc cttttattgc
    22921 cttttttgac aaaattccaa tcttcgctaa cattcttgca tactttattt aaaagatatt
    22981 ccaattgttt tgcttcttcg tcagaaagac catttaatgc gactgcattg gagtagttgt
    23041 tttctcgaat gatgaaagga tagatttctg ctcctttttt agtcggatag agtttcttga
    23101 tttttttatt ttctttatct tccaaacgtt cgatcatccc attggattct aatttcttga
    23161 ttgctcgggc agtcgttgta cgatctactt tgatcatttc tgctagtttt tcttggatga
    23221 ttccaggatt ttcgcaaata cgtactaaat aaagatactg tcctcttgtt aaatcgactt
    23281 ctttgaattc gatattgctg atagaatcta gcgctcgggc aatcattccg atgtctcgaa
    23341 ggatttcagc catttcatcc cacctttatt ttgtttgtaa gactagttta cctctttttg
    23401 ttgcaaatgc aactattttc aataaaaaaa tcaagttctt ttttaataac tagtaaagta
    23461 tattcttttc ttcttttacg aaaaagctca atcacaatag atctggtttt tgttttctaa
    23521 aataagtaac tgtttcttcg ttgttcgctt ttctgatagc tttggcaact cttctatact
    23581 aaaaaatccc atgttggaag tttcattatt ctcaataaac ttggcctctt caccgtggat
    23641 cgcacaagca aaaacaagtt tataatactg aaaaagctgt ggaatatctt tttgtttatt
    23701 cgtatcaaaa actgctcgca actgagtagt ttctactgtt aatcctgttt cttcatagac
    23761 ttctttacgc acattttctt caggagacaa tcctatttca gcaaatccac caggaagtga
    23821 ccattctttc gtccgtttat cttcgattag taggaccttg ccatcttttt tgatataggc
    23881 acgaacatct acttttggtg ttggatgtcc ttctccaatc gttgtgagcg cttttatttc
    23941 ttcgaaagtt tcttttccta tttcactgat cagttccaat gaaatcgtcc ggatctcctc
    24001 aaaacgctct ttatcaaata catcttttcc ataatataga ccagcttgag aaagtgcgag
    24061 tagtcttttg tattgagcca acttcttgtt cattctcttc ccttcttttt tagcaaatgt
    24121 atgactatgt aatcaagtat agaagactag tttaattacg gcaaataaat ataatgaaat
    24181 ctgcaataaa taaaagaatg ttaaaaaact cgagaacaaa agacattcga cttctctggg
    24241 gctgtgaata aatggcgttc aaaagcttgc atctgcggta ataagcccca ccaaacgaaa
    24301 aatatgacga gctattcttg tctggctgtt cttattaatt gaggcaggac agctttttca
    24361 caacctcccc actaaacggt gttcaatcag ctgatgctcg gtattcacta aaaaaacggc
    24421 aaaatatgag gagctatttt gccgtttttt tctataatac tcatattaaa acactgactt
    24481 cacaacctct tccttaaacg gtgttctcct accaactcct cagtcacaag tcacaatatt
    24541 catcaaacat gagaagctgt ttcttgaaat tgctccttgt gactcggtgc tgaacggtag
    24601 gctcacgacc tctcggtaaa cggcgttcaa aagccaattt ttcgatatta agccatttct
    24661 ttgttactta ttgtcattga ttttttttct aatttatcca atagtggagt gtaatccact
    24721 tgagtatagt ctgttacatc aaattcatat agtgttccta actggaattt gtcatatttt
    24781 cggtcggcga tgatcttttt gaatgcttct ttcgtaatat gattggtccc tttcgttcga
    24841 tcttccaata cgtcaccata gtgataatga tccatgatat agctcaaatg acgatctgat
    24901 tcacgatcac gtttgtaccg acgttgccat aacacttcaa agtctgctgt taggcgaatc
    24961 gtgatcacct gatatccgta tctatctgct aattcttgga gtcgtgcttt ttgcttatca
    25021 ctaaaaggat actcggacac aatcactttc tttcctgctt ccatatacaa atcaagtgct
    25081 ttgtaataga aaggataaac tttcgtcctt tcttgttccg cccgttcttc caaattgtta
    25141 aacccgatgg attctgcata gtattccttg atttcatcga gcgtgatggc atacatatct
    25201 ggaaatcgtt cccgtagttt attcataaga tatgtttttc ctgtaccagg actaccagcc
    25261 agaagaatga aatacttttt catctcattt atttcctaag ttaattggac tttccaagtt
    25321 cataaacagt ccaatcttat gcttgacaat ttcttttact gcttcatttg ctggaatcac
    25381 attatggcga agagacttgt tgatttctgt ttcactaaag gtttctttag ctactttcgt
    25441 ccagttgact aaaagctccg ttccaacatt gaatttgcgg atcccgttat tgatcaattc
    25501 aggataatct tcttctttca cacctgttcc tccatggata actaggggga catcaactac
    25561 tgcatcgatt tctttcagca agggaatgtt tacttctgtt tttgatttga attgtccatg
    25621 attcgtaccg atagcaatag ctaatgcatc cacgcctgta gcttctacaa atttcactgc
    25681 gtcttccggt cttgtatata ccttgtcatt ttcagcgaca tggattcctt cttctgtacc
    25741 gccgattgtt ccaagttctc cttctacgga aacaccgtgc gcatgggcat attctactac
    25801 tgcttttgtc ttcaggatat tttctttgaa aggcagatgg gacccatcat acatgacaga
    25861 agtatatccg ctgtcgattg cttctttgat atcatcaaag tctcgggcgt ggtctaagtg
    25921 caagactgca tcaaccattt cttcttctgc aatagctgtc attacattga ctaacacatg
    25981 catgctgata tatttagcag tatcgacact tgtttgaata atgattggcg aacccatttc
    26041 ttttgctgcg cctagcatgg caggaagcat ttctaggtta tgcgtattaa aagctccaac
    26101 tgtaaaattc aactcttctg ctgtttttgt tacttctttc aatgttgtat acatctttta
    26161 ttgccacctt atctttttat ttgtttcctt tgatcgttac ttgttttgca atttgtcgca
    26221 tctcatccat tttgcccatg tagtaatcga tcccttgatc atcaccagca cgagcagcat
    26281 ctgaacgctt ctggttatag aggctcatca gttttttata cccatctccg atcgtctgtt
    26341 tattttccaa gctcttttct aaatattgga tggcttgatc gttctcatac aattcagaaa
    26401 atttaagtcc aacttgttca taaagttccg ctaatttatg cctatcttgg gtagtggaaa
    26461 tctcttgttt caattgtgta atctctgatt gaatcttttc ggtcgcttct ggcgataggg
    26521 ctttttcttc ttttgccaga acttttttcg gttctttttc ttttttctta aaaaatccaa
    26581 acatcatttt ccctactttc aattaaaatg ctttcaaaac tgggcttaag atccaggcat
    26641 ataagagtgc tgcggctact gtatctacat cggttgctgt agcattgatg aatcccatcg
    26701 aattaaagat cgttactagc aaagcgggca ataatgtaat aaagaaacca tgagcaatac
    26761 cgccaatgat cgctcctcgg cgtccgccaa ctgcgttgcc aaatatccct gctgtccctc
    26821 cggcaaagaa attggttagc ataccagata aaatcatcgc taagccgaac atgggcaaag
    26881 taaacatggc aataatcgta ccaatcgttg tcgtaatgaa acctaaaatg acagcatttg
    26941 ggctataagg aaagaaaact ggacaatcta aggcagggat cgcatcagga actaatttca
    27001 tagctatccc tcgaaatgcc ggcacgattt cacctaacag tagacgtaca ccagctagca
    27061 atacatacac acccactacg aattggatgg cttgtaaaaa ggcaaacatg atatagtttt
    27121 gatctcctga taattcagaa gcgaatggtt cgcctgcaaa taaaacagtg atgatatata
    27181 gcgggaccat cacgaccatg acagacaaat aagtatcttg cagaaattcg aaatgtgtcg
    27241 gcaacttgat atcttcgatc gactttttat tttcgccttt ctcaccaaaa agcttagcga
    27301 caccggcttc aaataagtac ccgatcgtac aaaaatgacc taaagcaata tcatttgatc
    27361 cagtgatttt acgaatgatc ggttgcgcta ctgccggcat agcaatggcg aaacaagctc
    27421 cgataaaacc accgaccaag atcaatacga tccctcgcag accggcaaaa tagccaaaga
    27481 ctgtcgtcat cgttgccatc cataaaattg cttgaccatt gatagattca atagaaggga
    27541 tgatcccttg catatgaaat ccttcagtaa agattttccc gaaataagtt aaacttccaa
    27601 cgatgatgct cgaaccggca ctcaacactt gaaatcctag gagtgtcttt aacgtgccag
    27661 agatgacttg tcctgctgat ttcttctgca gtagtagacc caacatagca atcaatgcaa
    27721 tggtgatcga tgcctgagtc aaaatatttt cgatgataaa attgataacg ctcatgtttt
    27781 taccctcttt tctttttgta tttagataac tcccttatct tgcagaactg gggtgatttt
    27841 ttcttcaatt tcattttttg aaacaatatt tttcaaatag atcatcgccg ttttaggatc
    27901 aactgcgaac ttttcgaact gcgaacgaaa attttctgct gtgatgatca catctggttt
    27961 catggaaact gcggaagaaa tatcacaatg gtccagtttg gcttctactc ctaatttgtt
    28021 caaaacatcc tcagcagaca tctgtgctgc aaaactactt cctaaacctg cgccgcatac
    28081 gaataaaatg ttcaatttgt tcatctttgt tctcccccgt atcatttatt atttctcaac
    28141 tactgaaaaa agcagttgtt tgaaatcttc gatatttgtg cattcaatca atcgatccaa
    28201 cttctcttcg ttgttgatca attcaattag ttctttcatg atgttcagat gcgagtagga
    28261 gtctactgct gccaaacaaa aaataatctt tactggatcc atttcaggat taccgaaatc
    28321 gattggttgc tcaatcgtag ctacgctgac tcctaattta ttgaccccat cttctggtcg
    28381 ggcatgggct agtgccatgt gtttgccaat cacgatatac ggtccgtaat cattcactgc
    28441 acgaatcatc gcttcgacat agcgctcttc gacaatgttt tctttaacca atggtctagc
    28501 agctagttca atcgattcct cccaagtagt ggctttttct ttgatcatga tattgctgtc
    28561 cgtcaaaata tcttttaaca taggctggat ctcccttttg ttgatttcta aattgtttgt
    28621 ttcgaataat ttttctaact tgccatagat gattcgatct actcggccac cactttcttt
    28681 catgacatct attatttgag tgaataactc cgtcgattca tgactgttag gctctaaccg
    28741 ctgtagttct tcatttcttt tcaaaaagtc ttctataacc aagatattcg tctcagttaa
    28801 aatcggatcg acaactaaaa gcggcttatt tcgataattc aattgaaagg tgctgaaaac
    28861 cagattgaca tccaatttat ctactaattc gatttctttt gaacttaaaa ctgcagtaat
    28921 ctcgatctga ggaaactttt ctttcagatt ctctgctaac agatttccag tagccatccc
    28981 atggttacag acaacgactg atttataaac ataattcaag tctcgcttga ttacactggc
    29041 gatcgtcaaa aagtggatga caagaaaagc tatctcgtcc tccagtatct tgccaccaat
    29101 tacttcttcg atcgtaggaa caaaatgagt gactgcgcgg tagattggga aataatttgt
    29161 tcggatgttt tctttcaatg gattcatgac ttggatatga ttcttacaat cagtgcagcc
    29221 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
    29281 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
    29341 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
    29401 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
    29461 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
    29521 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
    29581 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
    29641 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
    29701 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
    29761 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
    29821 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
    29881 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
    29941 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
    30001 gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt acggatctcc
    30061 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
    30121 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
    30181 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
    30241 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
    30301 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
    30361 atacgcctat tattacaaaa attttgccca tccatacaaa aaagaggttg tgaaaaagct
    30421 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt ttttgtttgg
    30481 ttgttcttat tatcgcagat gcaagctttt gaacaccatt tagtggagaa gttgtgacag
    30541 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tagcttccca tattttacaa
    30601 aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga aaaaggagtt
    30661 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
    30721 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
    30781 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
    30841 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
    30901 gataatttcc tacttcctga atagttattt ttttaggtat gatttcttac accgtctgct
    30961 ttgttttttt gcagaacttt ctgattttcg gcaaacagct tgtctgtata acagcttctg
    31021 gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat cttttggatt
    31081 tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa tatctccgct
    31141 ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac ccctcctact
    31201 gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc tgtacttgga
    31261 ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact gcccccatat
    31321 gaacgaccgc caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc tccaccatga
    31381 ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc cactaacaaa
    31441 atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta ttacaaaaaa
    31501 ctatttttat catagccttg ctaaaaggaa gagtcaataa ccagatgcat aaactgtttt
    31561 tttagcaatt ttgtcttatt tagtcattga gtaacatcga acagatgtat gtgtcggcag
    31621 tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct gcgcttcctc
    31681 caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgaa cgatttggta
    31741 aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt ttctaatcac
    31801 tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac atatgcattt
    31861 gtttctgtac atatgaatca ttatctagct ccttagctgc ttggattgca agcctgatat
    31921 gcggataccc taatattgct tcttcatatg caccatttac gccatatttt tgcttcaccc
    31981 tatgaccatg agtgtttttt ttatgacgat attttgtatc aggaaaagca gcaagcttgc
    32041 tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt ttttgtgcaa
    32101 tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg atgccatttg
    32161 tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt tctcttaact
    32221 cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa ggagttagcg
    32281 tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc gcatccagtg
    32341 catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct tcctctacca
    32401 acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg acactcactc
    32461 cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg atatgaagta
    32521 accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga atcatgactc
    32581 ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg aaaacaaata
    32641 cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat ggcaattttg
    32701 gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg atgactaaac
    32761 tgtataaact ttggatcgta ttcaagtaag gcgcattcgc aaagctcaag tctcctggat
    32821 gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt aagaaaagat
    32881 aacgtactct gtccaaatat tgataaactt tttcatgata aacaaatgcg gctaccccat
    32941 aaatcccgta aatcatgaaa ctagcaacaa accgatctaa caagtaccag ctgtcatgat
    33001 aaggcccagt caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg
    33061 aaccaatcaa tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa
    33121 caaaaaacgg catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg
    33181 ctccatcacc tgtgacatat ttcagtaaaa agcttgcagt atcgtatacg gagtttgttg
    33241 ttggactgct ggaaatagcc aaagataagc cgtcgtccat agaagatacg gaacgactag
    33301 ttcaaaaaac ttttctttca aaaattccca ataagacaaa tgctggcttg tttttaccat
    33361 attataaaca attgcaaaaa taaacattgg tgctgtgtat ttaacgatga cgtaaaaggt
    33421 accaataaaa gctgtatttg ttgcgctgtg gctgtttgcc aaagcaaagc tcaatatcgt
    33481 ttgcatcata acagccttta cagctgatac tttctggaag tcacttacgt tgattttgat
    33541 ttttttgttt tcaaacatct ctttctctct ctttttcttt attaccaaag ttctttagtt
    33601 aatttaggtc cttcgactgt tttcaataga atttttttct ctggctctct caaatactct
    33661 tttagtgaaa aaccgccttg ccgagtcact acttgggtat cgaattgctc aaaaaaagca
    33721 ggatgcgatt gaattacctg aattggcaat tcaatcggtg aatttgcgta cagtagcaaa
    33781 tcaaaatcac tggtttcttt tactgccgga atcccagtcg ataattcaaa tcctaagctg
    33841 ccgccgattc cccatttaca tcctgataat atgtttctag cagcatgaaa ttgctgataa
    33901 acaggataat ccatgatttt ctcttgtcta tacgattctt gttcgatgat gtcccacgga
    33961 tgaatgactt gtttgacggc atgttttgag atttctgttg cccatctctg attgcgggca
    34021 ggtccacgta aaccaatcgg tagtatttct gcgtgatccg tcgacgcacg acgaactgtt
    34081 ccgaacatct tttcagttag aacgacccat tcaggcaagg tgaacccttc tatttcatgt
    34141 ttatcaaaaa ggacaatatc atgtgcttga atcatttttt atgcatccca ttcttcgtcc
    34201 attttggcac ggactttatt tgtttcgaca cgtccgaatg ttttggctgt ttcgtttgtg
    34261 tatcgatttg tcagcatcgt gtcatttgta ttgcggacat cttgaatggc ttcattgatt
    34321 gcttcgatga ctttgctgac attttgttct gaagcagctt ggtcggtgat atcttctagg
    34381 aaatgataga tcgctcctag ttttgtataa ttattgatat cgtaagcgat agctggaact
    34441 ttttcagcag ctgcttcgat ttcagcaacc gaacgttttg tcacacgtgc agcactttct
    34501 ttagacatcg cttggacggt aatttcttta ttgtttaaag caatcaagcg gcttgattgt
    34561 aatccatgtg ctaaaaatgc acctgaaata gcatttcctg caatcaatcc aataactgga
    34621 tatccagctt gacggaattt tgcataagca gcagcactat tagccaaagc cacatggata
    34681 ccgattaatt cttcgttata gccgtatgct tggcttggta catcgatcac aacgatgatt
    34741 ggccgtttca cttttttatc tttatcttct tcgtaaacgt gatccaaaat ttgtcccatg
    34801 cggaaacctt caactaaacc aacttcaccg tttcgtacac ggtacatcgg gtttttagga
    34861 tcaggtacga ttgatatcac gatggtttct tctatgaatt tacttgattt accataatac
    34921 acagtactaa tagaagaagt tggatttttc atgccagtta gtgccgcaaa ccaatcgtaa
    34981 ccaacacttg ctgcagctgg ttcatttcct tctgctactt ctggtaagtc aattgatttt
    35041 gcttgatggt tagcaattgc ttcattgtaa tcgtcaatgg ccattggttt tgaaagatct
    35101 aaagaatcaa gtaatgataa ataaaatgct gagctttcac tgcgatgcgt gtcttttcgt
    35161 tcgtccattg ctgcgatgac agcagctttg attgcttcta cactatcagt cactaattca
    35221 tcaatgattt ttgactctac ccgttgacga gatcctaatg tattccaaat aaagtctttg
    35281 tcactagaat caaattctcg aacgcctgct tcttgttcaa taacttctgg tccattcaaa
    35341 ccgactctcg ctttttttgt tgcgattaaa taactcatta atgctgaagt aatcgacata
    35401 ccgccaaatg atcctacacg tcctggaatc aaaccgatga ctggtacata ttgttttaga
    35461 gcaatgatta catttccgat ttctgaaata gataacagtc cgtagtttgc ttcttgcaaa
    35521 cgaacaccac ctgtatctag tacaatgact ggaaagatct catttccttt tttattttct
    35581 tctaacacat gttcaagtgc agcaacgatt tttgcaccgg aaacttcacc gataccgcca
    35641 ccttggaatt ttccttccat agcgattact actgcttgtt tgccattgat cgtgccacgg
    35701 ctgacaacga tcccgtcatc actttcaggg acgattcctt gtgctggcaa acttggcgcg
    35761 atgatttgat cgaatggatc aatcaattca cgtccattgt caagtagagc gttcactcgt
    35821 tctctggcgt ttaattctac aaaactattt ttcatctgaa agttcctcca ttgcttgcgt
    35881 caatcgtagg tacacaactc ctggtgtagc accgaagtca ttgatcacga tatctgctga
    35941 aattggataa cgatcaaaaa atctcgttaa tacattgttc catacttcgc cgaagccatc
    36001 gcttcctgta caaattttta cagtagattc tgttttttct gttggaaaca tcaagatttc
    36061 caaatctcct gaaccgacca ctcctacatg gattttctta ttgatcggct gtttcgttgg
    36121 atatttataa gctaattgtt ccatggatct ctcccctttt tgtaaaacag agcatacacg
    36181 ttctgcttat tcgtctttct tcttccatct gggtaaatgg cgacaaaagg tttttctcgc
    36241 caattttatg accaagttct gaatttcatt ggtggttcat acaggccatc tgaccattcg
    36301 atcaaatcat cgattgtttg tgcagctaat aatgaacgtt tcgcttcact gcgtttgata
    36361 cctagatctt ctggtaattt cacgatgccg gcttcacgca agctatctag tgattctttc
    36421 gtgctagtca ttccaagagg tgtaacaccg ccaattgctg caattgctgc ttgacgttct
    36481 tcttttgttt ttgctttgta caaataagca attccttctt ctgtcacgat atgggtagta
    36541 tcttcgctat agatcatcac tggtgcattg gctaagcctg cctgtttttg aacaactaat
    36601 gcatctaatt cttcgacaaa gactggtttt ttatttgaac catatgtttc aaccatttga
    36661 acaactaatt tttgtccttt acctaatgga tcatcattgt cgcgaagtga ttgccatgct
    36721 ggtgtagaat gacgacgacc gccaggatta tgtcccatgt taggcgctcc accaaaacca
    36781 gataaacgtc cttttgttac ggtagaagaa tttccttcgt aatctaattg caaggttgaa
    36841 ccgataaaca tatcgattgc atattgtcca gctgcttgtg ataatgttcg gttactgcgc
    36901 atcgtgccgt ctttaccgac gaaaaagaca tctgggcgag cagcaatata tttttccata
    36961 ccgacttcac caccgaaact atggatactt tcaacccaac ctgattcgat tgctggaatc
    37021 atcgttggat gtgggttcaa tacccagttc ttcgcgattt tcccttttaa ccctagtgat
    37081 tcaccataag ttggcagtaa taattcgata gctgctgtat tgaatccaat accgtgattc
    37141 aaagattgta cgccgtgctc tgcgtagatt cctttgattg ccatcattgc cattaggatt
    37201 tgcaattctg tgatgttttg aggatctcgt gtgaataaag cttctaattg ataaggttca
    37261 tctgctttta cgacaacgtc tacccagtca ccagggatat ctacacgtgg taaagaatcg
    37321 acaacttcat tgacttgaac gatcacgatg ccatctttga aagctgcagc ttcgacgatt
    37381 gttggtgttt cttccgtatt gaaacctgta tacaagttgc cgtctttatc tgctttatct
    37441 gcaactacta agacaacgtt tggtatcaaa tcgatgaata agcgtccata aagttccaaa
    37501 taagtatgga tatcacctaa tttcattgtg ccgtcttcaa tcatttgggc gacacgcaag
    37561 ctttgtgcac ctgcataaga gaaatcgatc ttgcttgcga ttcctttttc aaaaatattc
    37621 aaatgttctg gtcgtgagat actagacatg atcaaatgca gatcattcac tttttctgca
    37681 tctacttttt caagactttc tgaaagaaaa cttgcttgtt tttgattgtc gccttctaat
    37741 acaactttgt cgccgggagc aatcagtttt tccattactt ctacgatttt ttcagtttct
    37801 acatacttgc cattgagcaa gttgctgatt ttttccaatc gctgcgcttt tttttcgcgt
    37861 ttagaagccc agttgcggtt tggtttttcc ataattagtc atctccattt ttgatataga
    37921 aacgtggcgt catcaatacc atgttggtct agattgatcg tacggatccc tttatctaca
    37981 ccaaattttg tatgaatcag ctttgtcaaa gtattgccgg ggggaaattc aatcgtcaga
    38041 tccattccta attcttttgc caagtccatc atttggttcc actgcacagg gaaagctaga
    38101 ttttccaaca aatctttacg aatctcttct gcgtcctgag tggctcttcc atccgtattt
    38161 tttatataca aacatctggc atcagataga tggacagact gcatatacgg cttgaatttc
    38221 ttgaccgtat cattcatcaa gagacagtga gatggcacag ggactttcag cagcttcgct
    38281 gtttgcgctt ggtgccgttt ggcttctgcc aacgtaacgg ataaaccttc gatactccca
    38341 gataacgtat gttgcatcgg acaattttca tttgacagat aaactggatg gtcaggatca
    38401 aatgttttgg ctaccatttc ctctgcttcg cttctcgtca cacctactac tacgcccatt
    38461 gcataaccgc ttggatatgc ttctttcatc aagactgcgc ggtgatagac tagttccgct
    38521 gcattctcaa atgtcaaaga tcgacaagca acagctgcac aaaaagcacc gatcgaatgt
    38581 cctgctgcaa tatcaggctg aataccattt ttttccattt catctaaata aaatactgct
    38641 tttgtcagta atgctagctg gataaaaacc gtatcttgat agttttcttc tttatcgact
    38701 aaccgatacc ccgtcacatt ttctaaacgt tccatgtaca tttcagggat atccgctaac
    38761 atccctaact tctgactgcc ttgtccagga aataagaaac ctgtactcat gagcctcgcc
    38821 tcctcagcac ttactttttc cactgctatc ttagtcaatt tctgctataa taaaaaatgc
    38881 caaaaaaaga aaaaaccata acaaaaaggt atggatggga tggataatta tgaaattgct
    38941 tcatctgcag tattttaaaa aagtattcga aacaaaaaat gttacccaag cagccaaaga
    39001 attatttatt tctcaacctg ccttgagccg tgcgatcaaa catttggaaa acgaattagg
    39061 tgtccctttg ttttaccata gcggcagaaa cattgagacg accgtttatg cagaagaatt
    39121 ttatccatat gcagtcaaga cattatacac attagaagaa ggaatcaatt attgtcttcg
    39181 gtcaatgaga agatcgttac ttccgtcata ttgtatttag aggtagcttc tgtttctatt
    39241 ccgaacttag tccgaatttt tatggaaaag catcctgata tccaattaac gatcatgcaa
    39301 catcatttac cagatgatat taccgatcct gtactgtaca tcacttcgga gatgaagcct
    39361 ggcatgacca atattcctat catgaaagaa cctgtttatg tcgccattcc taagaaacat
    39421 cctcttgcga aaaaagaaca tctgcaatta gaagatatcc agcgcacccc catcttgatg
    39481 ctgtcaaaga gcaacgcctt ccgtcataca ctggatgcag cacttgaagc gaaaagtatc
    39541 gaattgacga tcagttcgac gacagatgat cctgcgacat tacgttctat tgtcaagcaa
    39601 ggattagctg ttagcttttt cccaaaagtt tcttggtctt acgataaaaa tgatcctttc
    39661 gtcttgcggg aaatcaaaga tttgcccttg acacgaacaa tttatttatc ttctagcttc
    39721 acagaagatc atcctttgat caaaatgatt gcaaaaacga tgcgggaatt ttatttagga
    39781 aaataaaaaa aaaagagctg ggacaaaatt cttgtcgcag ctcttttttc gaacaaacgg
    39841 tgttccagaa gtaatttctt agaaaataag ccgaaatttc ccaaaaattt gagaagcaat
    39901 tttcgtaaat tccttcttat ttcttgaagc taaacatttc tgtcacaacc tcttctctat
    39961 tgtcctagac attcattgcg ttgatttaaa acttccatca atcaaatctg ctagttcatc
    40021 tagcttttct attttacgta gatcaataga gatccaatgt tctttattca tgtgataggc
    40081 tggaaaatac ccctcttttc ctcgcaaaat tccgccaagt tcaggatcga ccttcaaatc
    40141 aagaatattg atgatcctat ggtcacttgc atcatcatag attttttctt ctggaacaga
    40201 catcaggacc ccaaaccatt ttttgctttt ttgatgtctg aatacgcaat aatcaggaaa
    40261 ttttttaaaa atatattctg gagacaaatt gtatgtttca ttgatgtgat cgattagttc
    40321 ttttttcgtt agcatctgct tccatctctt tcttattgat tcgctttatt caaagatacc
    40381 acgtaagaat agaaaaatga atacaagtag ctgctaatca aatacttcga tatttttctt
    40441 ttttatcaac tcttaaatgt tcaatccgcc tgtgttggtc ttgctatcat ctactattaa
    40501 aatgttgatt attgtttgcc cacctatttt ttgattttag tggtatcatt tttcaagttc
    40561 atgatgaaat tcttatcatc agtaaatgct ccagaaaaat aaacaatgat tgaaaaatca
    40621 gttgaaactt gaccaccgtt tattttctcc gtattcttag aatagaaggg agtctgattg
    40681 atgtattcac taatgaaaaa aatcattacc gaaaaagata ttcgacgtca tgtttcttta
    40741 gtagaacaat tgctgaatca tacaaagata accgtaaatg aattagctga aatcataggg
    40801 acaaccgaac gaacgattta ttctgacctt caatctattc gctctcaact gcctgaaggc
    40861 tgggacatca ttagcgatca agcagggatt agtttgcaaa accagcaaaa tttattagca
    40921 aatgaccttt gggagatttt tttcaaacaa tcagtcagtg tcgaactatt gaaaagtctg
    40981 ctttttacaa aaaaagttgc tgtccctgat tttctagccg accatgggct ttcttatggg
    41041 acattgaaaa gacatgtgac taaaatcaat cagcgtttag caagttacga cttgcagatc
    41101 gatttgacga aatataccgc ttctattctt gggaaagagc gtgcgattcg cactttctat
    41161 catcgactgc tgattccttt tactcataac aactattttt tcgaagatta ttcgattcat
    41221 gaatcccatt attttcaatt tttaaaaaca ataaatcgaa cggagctagc ggttgaaaca
    41281 gaagagattt ttggaacatg ttggttcttt atcaatacga tccgtataaa agcgaattgc
    41341 cgattagatt cttctatcca tatcaacagt acactctcct ccctgtatga ctctgcattg
    41401 aaaaaattgt atttaacgga aggtatttat ctcaaagaca ctgagctttc ttttgcttct
    41461 ttctgctttc tggaaagttg gaattacaac aataactatg gacaagaaac cgcttgctgc
    41521 ctgcatcatt ctccattttt cgaacgcctc gaaacgtttg tagaggaact agcttcagag
    41581 ctgtctcttg atcaactaaa aaaacatctc taactgataa cttggctctt ctcgtattaa
    41641 aatatcatga atcgccgata ttgattgaag cattggaccg tcaataccat tttttttaga
    41701 aacatatgat cagcaatatg cacatttgtc tcaacagaaa gagaatttac tgaacgatct
    41761 aaaaaaagaa atggaaatca atgaaccgaa tttcttcctt caactcttat ctttactgat
    41821 ccaacaaacg attttttcta tcaaaccgaa tttgttcaat gtctatttta ttttccaagg
    41881 agaaccttca tggaaggcat tctttcagca ggaattaaaa gattacctgg gaaaacgtgt
    41941 ctgcttctta cctatcgaac taaccgatct ttccactatt tctttcgaaa aaacagatat
    42001 cttgatttcc aatttcccgc tggattctct agatatccct atcgtataca tttcttctat
    42061 tcctacgaaa aatgagctca atcgtttgac tgaactcact ttcaaaactt ttttatagta
    42121 acggctagcg actgtattct ctagctgttt tttctttttt gcgaaacagt ttattcatga
    42181 tccctttttc tatttctaca actaagaata gaagaatcac atttgctcca atcaataact
    42241 gttgtgtcat cgttaaactt actgtaccga tcagctgctg gccgactggt agaaaaataa
    42301 ccatcccttg caataaagca aggataccta atgaaagaaa aagcgctttg ttttgcaaaa
    42361 gaccctggtt caatgacggc ttggacaact ctctgcaatt gatcatgtaa acagcttgag
    42421 ctaagacgat attttgtaga agaatggttt gctgtaagct ttgcccttca aactgcatag
    42481 ccaataaata ggcaggaacc atgatcagta gggagacata gatgatccga aacaaatgat
    42541 aaccagatag gattccttgc tttggatctc ttggtgggcg cttcatgatt tctggatctg
    42601 gcgactcgaa ccctagtgca taagataaag tgattgtcgt taccatattg acccataaaa
    42661 tctgtactgg gaacaaaggt agcgggcgat tcagcataag cgcccaaatc aagatcaatc
    42721 cttgagctaa tgcagttggc aagaagaaat tgatggtttt ttgcaaatta tccaaaatcc
    42781 gccggccctc ttttacggct tttgcaatcg tatggaaatt atcatctcct aaaaccatat
    42841 cagctgcctg tttgcttact tcactacctt tgattctcat agcaattcct acatcggatc
    42901 ttttcaaagc aggtgcatca tttacgccgt ctccggtcat tccaacgatt tatccatttt
    42961 tctgcaaagc tttaacaatt cgcagtttat gttctggcgt cgttcgagca aagacatcga
    43021 ctattggcac ttgctgaatc aactcttcat cagacataag atccaaatcg atctcttcta
    43081 aaactttggc agtatgtttt aagccaattt gttccgcaat cgcttttgct gtgtctttgt
    43141 gatcccctgt aatcattttc actgagatcc ctgcttgttg acattccttt acagctttga
    43201 ctgcactttc ttttggcgga tcgatcaatc cggcgatccc tgcaaaagtt aattgggtta
    43261 aagtctcatg cgtgagttcc tgtttcgaat ctactttttt ataagcaaat cctaaaacac
    43321 gctgaccttt tctcgcaaat tctgcagctg tctgactcca tgcttcttgt tctgcagaag
    43381 aaagagttga tttagcaaat aatacttctg atgcaccttt gacgtaaatc accgctcctt
    43441 tttcctccgc atgcatcgtt gccatatatt tgtattcaga actgaacgga atctttgctt
    43501 ctattttttt caaaggcaga ttggctgttt ctgtgtgtcg aatcagcgca acttctgtcg
    43561 gattaccact taaattttct gttttctgtt cttcttttgt ttttaattcc tgacagtttt
    43621 tcataatgga caacacgcag gcttcttctt ttgcagctac atccacaact gtcatttcat
    43681 tttttgtcaa tgttcctgtc ttatctgaac agatcactgt catagaacct aatgtttcta
    43741 ccgaaggaag tcctttgatg atcgcctttt cttttgccat ttcatgtact ccaacggata
    43801 ggatcatggt caaaacagct ggcaatcctt cgggtaccat tgacaccacc aaagcaatca
    43861 tagccgaaag aaggatatgc caatccatac catatcgaaa tgtcgtaaaa ataactaaga
    43921 ataggctcaa acaaagaatg ccttgaaaaa tttgtttgtt taatcggttg attttcttaa
    43981 tcagaggcgt cgtttgttgt tcgacctatt gcaatgcttg attgatttta ccgatttctg
    44041 tcgtgtttcc tgtttctaca acgacaccga ctgcagaacc agattgtaca agcgttcctg
    44101 aaaaagccat atttttctgg tcgccgatcg attcttcttc tgtcaaaacg gcatgacttt
    44161 tttcagatgc ttctgattct cccgtcaaaa tcgattcttc cactaataaa tcatgtgctt
    44221 cgattaatcg gatatctgct ggaacgacat ctccggcacg taagacaatg acatctcctt
    44281 ttaccagttc tttcgcaggg attttttctt gcatcccgtt tgatagtact atcgcttctt
    44341 gtcccatcag ctgcttcaaa ccattcaatg attcttccgc ttttctttct tgccagtaac
    44401 taacgagtcc attgacgatc actacgaata aaataatact tccttcaata tattcactag
    44461 aagcaaattt caaaaaagag gcaatgatca acacgatcat tagcagatca gtaaagtgct
    44521 ttgctatttt tttccatcgt tttgtctgct gccttgcttt tatttcatta tatccttgat
    44581 cagtcaggcg tttctgtcgt tcttcttgcg acaagccttc tgttgatgtt tgatagtttt
    44641 tcaatacatc ttctaccgtc aatctgtacc agttcatcct atcccctcct gtttaattga
    44701 tactgttatt atacgcaggg aagttttttc aggcgtatcg attatttcag gggggtctga
    44761 aataattcgt tttgcagaat gtatctgggc ctaactgata tttctattgc ttattctttt
    44821 atatacaaaa tttaagaata caaaccagat aaccaataaa aaaggaataa agcgtgtcgt
    44881 gctttcgaat aacaagctga aagcaattga agtaaaaaac accaacaaag caagatcttt
    44941 atatctttgt gtagtgttcc gtttcttttc tttaataaat tgaacatgtg tacacaagat
    45001 cgaagaccac acaaatagaa aacaactcgt tgtcatgcct gccaaaagct gaaaaaacaa
    45061 tcgactatca gctacaaaaa aatgtagaca aagaccggca aaaaataaca ttcctgtaat
    45121 taaaataccg tgtaaaggta cgcctttctt agaaagcgca caaaaccaat ggggcaaact
    45181 tttctctttt gctgtttgat ataaaatcct gctagtactg tagactgcac tatttgctga
    45241 ggacaaagaa gcaaccaaaa tcattagatt gacaattgct gctccgcctt ggcaatggat
    45301 catttgcagc atagtcacta aaggactttc ttttaaatct aaacaatgcc atggaacaac
    45361 aaataaaatc gacaaaatcg ttcctatata gaaaaagaga atacgccaag gcagacagtt
    45421 gattgctttt ttcaaattct tttgcggatc acttgtctcg ccaacggtta acccgatcat
    45481 ttcaattcca gcaaaactga ataaaaccat aggaaatgag actaccattc cagcaaagcc
    45541 aaacggtagt aattcatcga tctgtccaaa attttctttg attccgatag actgggtatg
    45601 aaaatctgag acactcaatc ctatacccaa taagataaaa aggaaaatcc ctaggatctt
    45661 gatgattgag aaaaaagatt ccaattcacc aaaccacttg actgcaacaa ggttgactgc
    45721 cattaagatc attagtgcgc tacctccgct tatcaaagct ggtacatgta caaaccagaa
    45781 atggatatac aatcctattg ctgctaattc cgcaagtcca gctccaagcc agcaaagcca
    45841 ataagtccaa ttgacaaaaa atgcccactt tttgcctaaa taatagtcaa cgaaatcact
    45901 gatagagtta aatgtactat ttgctaaaaa taaatcaccc atggcccgca tcaaactata
    45961 aatagccaaa ccgcatatca aataaacgag aataacagct ggccctgctg atgcaattgc
    46021 ctttgctgaa cctaaaaata atcctgttcc aattgcgcca cctaatgcga ttaactggat
    46081 atttcgatta gttagagtcc gtttcattgc cggtttttcc atcaagttca cctttttctt
    46141 tttcaagcag catggcgact tcctgttccc aagaaggttt ctttattttt tcaatacaga
    46201 gtggtactac aaacaaaatg acactgatgg ctgtgactgc aattagattg atccatgttc
    46261 cagctttcat cgtcagtccg acagaaaatc cgattgccgc aaataaaaca ataacgacag
    46321 tccaaactcc aagattgctc tttttctctt tttttccaat tctaaatggt cgattcaact
    46381 ttgcatgtgt ataacgcaat ctcaaaactg cgatccccat gatgacatag acgatacagt
    46441 agataacagt agttgaattt acgagcatca aaaatgcttg attgacgcca ggaatcagca
    46501 aataaaaaag tgcaaagatt gagataatga cagactgagt caaaataacg gatttggata
    46561 cgtcaaattg attcgtcttc caaaaattga attttggtgg atacgcacct tttctagcac
    46621 tttctgtcac tgtctttgct ggtcctgagg cccaagcaga taattggact gctacaccaa
    46681 tgaagacaag taaactaaac agattcacaa taagatgtgg caaaccaaga atttggcaat
    46741 aaatcgaaat agattgcgcg atattattca attccatttg tccttttggt acgacatttg
    46801 ctacaactaa agcattcaaa atattgacga aaaatataaa aattaacgcg gcaaatactc
    46861 cgcgaatata cgttttaact ggatttttca atcgagtgat atacacagag gacatttcga
    46921 taccagtaaa aataaacatg atcggcgcaa aataaacaaa tgaggatgca gtcgtagtat
    46981 ctggtattaa tttgtcccat gaaaaactgc ctaatgttcc ggttggtacg atcccaactt
    47041 tgatccacgc agcaaaccct aataagagca tcatcgtcaa aggcacgtac aatcctaacc
    47101 aaacaccgac ttttccgccg atttttgcca tatcaaattt caaattcaaa aaagtgatga
    47161 tccaataaac gactaaaata acaactaatg taaatttgct gttcaaacca agcggcacat
    47221 tatcgataat attaccaaac aacggagcaa gtgctgaagc gaccatcacc atcccaggaa
    47281 acatttggac ccataacagc catgagacaa cgaaccccca tttttttcct agagcattcg
    47341 atacccaaag ttctggacca ccttttttgg gaaacattcc ggcaaattca ccagagatca
    47401 atgagattgg aaaagcgtac aataatactg caaccagcat gtaaaaaatc atcgtccagc
    47461 tcgttgctgc tacatctgga atatttcgta cacttgctac aagggcgcag gtcattccga
    47521 taaaggtcat ggtcgtgatt tgctttgatg aaccagtatc tttcatcttt attccttctt
    47581 tcaatagcga catatgtttt tgttttcttt tatttttgtt caagaacaga aatgacaagg
    47641 tttcatcgat tcagtacaaa acccagtatc accgaaacat ccattgaacg atcttagtga
    47701 actgggtttg atacatgaaa cgaacgatcc aacttataga acgttttata aaaaagaata
    47761 tcttggcgag gaatatatga aaaacagggg gaaatacaat tgttttgatg aagcaaataa
    47821 ttgtctgttc tccatatgtc tcttgctatt ctttcacaca aaaatcagtt ctattggatg
    47881 atttcgttta gtttcttttc cattgctttg gcgatttctt ttgtataaaa attgaaaatt
    47941 cgatcatcat tcaaataagg agtcatgata gccgcacgta gcagagtgat tttctgttct
    48001 tttttccatt cttctttcgt tagacccatt ctttcaacaa aacgaatcgg agaatcaccg
    48061 taatcttctt gtgtaaatgt agtatgagaa gtaataaacc gttcaccata aacatcgcca
    48121 tccatataag aagaccgatc gaacattttt tcatttaatt cattgatagc gttcaaatct
    48181 gtacagcctt gttctttgaa tacccaattg accatattaa aatcaggatg attcaatgga
    48241 tagacttcga ttgtttttcc tttaacagta aaagtcatat gatcgagaaa ttctctgaat
    48301 ctttgagctg cctcgattga agccccaatc aattgaccgt atccggtcac attcaatggc
    48361 aatacacgat gtgttgtcca gactgcggcg gcggttgctc cagcttttga tccttccaaa
    48421 atataagctc ctaacatatc tggagccttt actgattttt caaacacata tggcgcgaaa
    48481 taagaaatga tatttctcat atttttatgt ttgattacga ttcctccagc agcataaggg
    48541 acatagccca tcttatgagg atctatcgtg acagaatccg cttctgaaat agctctgaac
    48601 ccttcatata cctctttgtc aatcgttacg cagtggtgga aaacatgatg ttcttcaaag
    48661 aattcagcta aggaagcata cggcacaaat tctcctgctt cgtttagaaa cagtgaacgc
    48721 gcatagccgc catatgcggc atcaacatgt aaatagaaat agataccttc atcttttaac
    48781 ctttctctta attggacgat tttatctaca ctgtctactt gaccttcttc tgtcgttcct
    48841 acgacagcaa ccacacctag aattgggatt ttttgttcag ctaattcacg aattgttttt
    48901 tccaaagcat taatatccat tcgataatcc tcttgaactg ggatagcaac catctgatct
    48961 aagccgactc cgcaaatatc taacgccttc atccaagaat agtgttttgt ttgagggacc
    49021 agccatttcc ctaatctttg gatatttttt ccgctacggg aagaagctgc tttgacctca
    49081 tccatttctt cgtccgtaaa gctttcggtc atttccaaaa tttcttcaac agataaattc
    49141 aaaagttccc actcagacat ttttttcact ttttcaggca gcacttcctt gacagctaaa
    49201 ggaatcgatt tgatgcagcg ggcgtaccat aatccttcaa gattagcaat agaaccatct
    49261 gctgcaatgt gtccccatcc gtctgtcata ttgaataatg aagcaaaatc ctgtcctact
    49321 tctgcttcca tttgcgaagt tgccatagaa gattccaatg caacattatt tgggttccac
    49381 agcatcgcat agttgtaagc taataaagca ggcatcaatg tttcagcatt catttgtccc
    49441 cagtaacggc ctgctgaatg ccatgggatc gatcctgcgc gtaatcgctg actgacttca
    49501 tccaagacct ctatcatatg gtcgcgggtg gctagataat ctggagtgag cttatctcct
    49561 tcgctaattg caggcatatc tgaaggaata taattttctc tccatccaag atgttcatct
    49621 accatcttgt tcaacaacat tttataaact ggtccatttt cagctttgtc gcctataaag
    49681 acggccttga tatccatatc tttcattttt cttccctcca tattttgttg gtcaatgtct
    49741 cgcagataca tgtgtttatc tgtaacacct cttcactata gcgccaaaaa tgagaaattt
    49801 tttttataac atcaaatcca cgtagatttt tacaaacaaa aataaataaa gtcggatttt
    49861 tctgataatt aaacgcaaaa aaacgaacat tttttcaata aatcagtgtt ctaaaataga
    49921 taacctaaaa aaagcgaaca aacaaataaa atgactgtcc ttcattcact aaacatattt
    49981 ttattttttt atattgttaa aaattcacaa tttatttttt aatagaatta tctgttttcc
    50041 aaattttata acataaaaaa ccttttttaa cggcatttat atgctttttc agaaattaac
    50101 tgatgatttc aaaaagaaaa catgtcataa tatttcccat attgtgcaaa aaaatacaag
    50161 gcggaggctc tactatgatt gaagaatata ttgagaaaaa tattttaaga cagctgtttt
    50221 tatgtgggca attctatgta aataaagaag tcaatctaga aaagctctcc aatctcctgc
    50281 atgtttgcaa aaccactttg ctcaatgata tcaataacat aaaaaaagaa tttgaagaac
    50341 agatcgctta tacacatcgg gaaaaggacc gttacacttt atatttttca gaacatatac
    50401 ctcgatgcaa gatcatgcag caagtgtctc aaaattcgtt gtttttaaaa acttgtctgc
    50461 tttatttgga agaagatgaa cctgattatc ttcaattaac tgaatgtgaa ttcatctctg
    50521 tcagcaaagc ttattcatta aaaaaacaag tattagctta ttttaatgac tgcgggatcg
    50581 aaatcgaccg ctactcccct cgactcactg aaatggaaag acgtctgctg cttcttaatg
    50641 tgtcgtatcg tttaggcggt tttaattctt gggagctacc tgaatcgttt tttgaacgta
    50701 ccgatcgttt cattgaatcc gtaacggaaa atagtggcag attttatgat aaagaaaata
    50761 aagaaatctt atcgattggt tttgctatca gtttcctacg ccagcaagtg tgtgctgtga
    50821 caatagattc aaaatttatc gaagaaatca aaaaacgtcc tatttacaat tatgtcgaat
    50881 cagcatggga aaacactgat ttccaaacct attataaaaa agaagaattc gcctttattt
    50941 tgacactatt caatctttgt aattatggtt tccattctta tcagttgatt gcggaagact
    51001 ttcaacagct acaccaagtg tttattgaca atactcccga aataaaagaa ctagttgcta
    51061 cctttgaatc tcacttcaat caagaattat tcggaaacca accgttcgaa cgtgcgctga
    51121 ttcatctgat gcgttcggct tgggataact atcaattatt catgccagaa aaattttatc
    51181 ttttaaatga ggaacagaca aatttatata aagaagtcca gacaattttt tccagctggt
    51241 ccagccagtt accttatgat ctacggttga atcctaattg catgcgggct tttgtgatcg
    51301 aattgagcgg aattctccgt ctgacaaaag aacatctgac tatctatatc gtcacaaatt
    51361 cggatgttca ttatctgatt tatcgggaag ccttggaagc tgtaactact ttcgattttc
    51421 aagttgcacc aacaatttat tcaagtatat ctgatataaa gaagtatgcg cagcagtcct
    51481 caaaccgggt attatgtgaa cgtacattat atacaccaga tgcggtccaa tatgaaaata
    51541 ttattcctat ttcgatcaat acgatcgatc gagctatcat ttcagctgtg caaaacaaat
    51601 aaggggctgt gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc ccatttctgt
    51661 aacaatctct tgatacacgt caggctcaca acctcactta ttttggacat ctacgggtcc
    51721 gatctcttta tttaaaaaat aagaaatgat ggttcggata actaccaacg ccgctagttg
    51781 gaaaatatcc tgcaaggtag gtttgataat cgattcgatg atcccagctg aaacaagaat
    51841 ttccaaactt agaagtatat agcctcccaa catcttttta atagcattgt tctcgctgac
    51901 tcggtcgttt tgcacttttg tatggacaaa taaatatttc aaaaaatcct tgattgatag
    51961 acaaacaccc caaaccaata aacagatagc aaagatatca agtcccagta caagtttttc
    52021 aaaatatgga agaagaaact gcatcaactc tgtcgtcatc ctacctctcc tcttctttgt
    52081 ttttctttgt cttctatttc ctgattcaag aaataagaaa tgactgttcg aatgataata
    52141 ataagtgcaa gcttcaaaat atctgtccaa gtcggcttga taactgactc gatgatatca
    52201 gcaacgacta gtacttccaa gcttaacaaa atataacttg ctagcagttt tcttgtatct
    52261 gcattacgag tattacgttc tgcatagttt ttcttgacat gagaccaatc aaaaagtttg
    52321 aatagaacaa gaacgatccc gacaattaag ataccgatag aacaaatatt taaaatagca
    52381 atgatccatt ctagaaattc aattaaattt gagcgaaaca tatacgctac ctactttctt
    52441 ttaatttgtt cctattcttt tattgtaaaa gaaagttacc ttgttcgtct atttaaaagt
    52501 tgttctaatg ataacggttc gcttaaattt ttctttttca ctctcccatt tttctcccct
    52561 catccataaa tcgtggaagt atccaaaaca acgtagcaag ttaaaataag gcttagtccg
    52621 tcatcagctt ttcaaagaag cactgtctcg gtgctttttt gtacccaaac ttctaaaaat
    52681 agaaccatac acctcctcaa atcttttctt cttacctacc ctatttttat ttacaggaaa
    52741 atcagacact tcttcttttt tgtcaaaatt tcctttttct tctcgtccta tcatttggca
    52801 ttctaataaa aacgaactat ccttggatat agaaagagaa aacaaggagg cgtttttcat
    52861 gagtaaaaaa ttaatcaaag tcggcatcgg tttaggtttg cttgcccttg gcgctgcata
    52921 tctaggaaaa aagacaggac tattcgaaga tgacagtcat ttatatgatg aattcgaatc
    52981 aatctagcat cctatttcgt tgaatcacta cggacatact tgaaagacat tggaggaatc
    53041 acaatgagaa aaagtaaatc aataatgatt ggtgccggta ttgccaatat ggcagcggct
    53101 gtttatttga ttcaagaagg caaatggaaa ggggatcaga tcacctttta ttcattggat
    53161 gatcacggtt caaatgatgg tgcaccgacc gacactgtag tggatgaata ttggaataaa
    53221 aaccatccat tagaaaacca aaaaggctat attgctcgag gcggtcgcat gcttaattac
    53281 cgtacctatg tagatttgat ggatctgtta agtcgaatac cttctgttac tgagccaggg
    53341 atgactgctg aagaagatac gagagatttt gatgcaaaac accgaacctt tgacaaagca
    53401 cgtttgatgg aaggtggcaa aggaatcatt gatggcggaa aactgggatt caataataaa
    53461 gaccgtattc ttctgactaa actgattgct atgcctgatt cagaagaaga aaaactagac
    53521 aatatcacta tcgaagaata tttcaaagat gatccacact tttttgaaac aaacttctgg
    53581 tttatgtggg aaacaacatt tgctttcaga acacgtagtt ctgctcaaga attgcgtcgc
    53641 tatatgcatc aaatgattta tgaattcact caaatcgaac atctagtggg cgtcaatcga
    53701 acacgttaca atcaatacga aagtattatg cttcctttga tcgagtactt gaaagaacaa
    53761 ggatgcaaaa tcattttgaa ccgccgtgtc actgactggg aattcaaaga aacaccgatg
    53821 caagatgaaa tcactgtgac tggtttgaaa atgaccaata cactgactca agaagaagaa
    53881 cacgttgtgg tcgatgaaga tacagcagtt attttcacta atgggtccat tacagattca
    53941 gctactttag gagattacga aacaccagct gtagaaaata tggattatgg tgcagcttct
    54001 agtctctgga aaaaagccag tgaacgtttc tacaacttgg gaaatcctga caaattcttt
    54061 gctgatcgag atgcaagcga atgggtcagc tttaccctga cgacgaaaaa ccatttgttg
    54121 ttgaatgaaa tcacccgtat cacgactcaa gaaccaggaa atgccttgaa ttcatttatt
    54181 tcaaccacac cgatcacgcc gttaggccaa aaagatgtca atatgtctat cgtcgtgcat
    54241 catcaaccgc attttacgtc tcagaaatca aatgaaacag ttatttgggg ttatttcctt
    54301 tatccaagac gacgtggcga atttgtggat aaacagtata ttaaaatgaa tggaaaagaa
    54361 atgctagaag aactgatcgg acaactttca aaagtagatc ctggaccagt gaatattcgt
    54421 gaaaaagaaa cagaaatttt cgacagcgtg ataaataata tccctgtcta tatgccttat
    54481 gcttccgcgt tgttcaataa tcgtgccaaa agcgatcggc caaaagtcat tcctaaacat
    54541 tcgaccaatc tggcctttac aggagaattt gtcgagcagc cttatcagat gatctttact
    54601 gaacaaagtg ctgtacgttc tggagaaatc gctgctttcc attttgcggg tatccctatg
    54661 tcccgtcttg tcaaaacacc gcgttacgac aaagatattc ctactctagc tcgtgccgca
    54721 aaaaaaatgt ttgaataacc aagaggttgt gaaaaagctg acctgcatca agtaataaga
    54781 acaaccaggc taaaacagct tcttatgttt ttgatttggt tggacttatt accgcagatg
    54841 caagcttttg aacaccgttt accaagaggt tgtgaaaaag ctgacctgca tcaagtaata
    54901 agaacaccca agctaaaaca gcttcttatg tttttgactt ggttggactt attaccgcag
    54961 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aagctgacct gcatcaagta
    55021 ataagaacac ccaagctaaa acagcttctt atgtttttga cttggttaga cttattaccg
    55081 cagatgcaag cttttgaaca ccgtttacca agaagttatg aaaaaggcgt ttagtttcga
    55141 gtatgaagaa aaattttgtg aaaatggttc ctcacgtttt tgcataaatt tgacttaata
    55201 ccgagaaact gatcccttct gtcataacct ctttttattt atgtctgttt ctttttgaaa
    55261 acaaccattt tttcaacgtt tactctcttg ccaatccaac atcatctaac ggatacaact
    55321 atttcaatga ttaccattac actaaaaaat cggaaacaca cctctccgaa cacaaataca
    55381 taagactata gaatgtttca tttaagaaaa aaagcgtttc attatcaaaa aggtaagatc
    55441 tcctttaaaa tgaaattatc tgtagtacta ataatgcaga caattttatg aatttgaaag
    55501 gagcatctcc aatgaaagca gtcacttggc aaggaaaaca gaaaatggaa atcagaaacg
    55561 tagatgatcc aaaaatatta gaaccaacag atgcaatcat ccgtatcaca gcaacagcca
    55621 tttgcggctc cgatctgcat ctttaccatc atggtgaagc agttttggaa aaagggtatg
    55681 ttgtaggaca cgaaccaatg ggaatcgttg aagaagtggg atctcaagtt caaacattga
    55741 aaaaagggca acgtgtggtt atccctttta atattagttg tggtcattgt catttctgcc
    55801 tgaatcacat ggaaagccaa tgcgatgaat caaatccaga tcagttatat ggcgggcttt
    55861 tcggatttgg caagttgaac ggtaatcatt ggggtggtca agcggaatat ctaagagttc
    55921 cttatgcaga ctctacttca tttgttgtac cagataatgt tcttcctgat gaaaaagttt
    55981 tatttctatc agatattttg cccacagctt attggagcgt tgaaaacgca ggagtaaaaa
    56041 aaggcgatac agttgtgatt ctaggttctg gtccagtcgg tctattcgct caaaaattcg
    56101 ctgttatggc tggagcagag cgcgtgatcg cagtagatcc agtacagcac cgtctagata
    56161 aagcggctaa ttacaatggg gttgaaactt atttcttaga agacacggca caagctggaa
    56221 cagaattgta tgaactggct aaaggtggcg cagatgtcat tatcgattgt gtaggaatgg
    56281 acggattaga gcctgtcaaa gaaaaagcga aaaatttagt aagcttacaa agcggcacaa
    56341 tctctccatt acagatggca tcgcaagctg tcaaaaaatt tggaacagtc caagtaactg
    56401 gtgtttatat gactccagct tcttcttacc cgctgcaaga attttttatg cgggatatcg
    56461 ctgtcaagca tggacaggca ccaattatcc atctaatgcc aaaaatttac gaaatgatcg
    56521 cagaaggact attcgatccc acacaaatca ttactcattc gctgccacta tcagaagcag
    56581 cacaagcata tgaaatcttt gacaaaaaag aagataaaaa tataaaagtt gttttgaaac
    56641 cttgaattca gtaaaaaata caggtgattt tctttatgcc caaaatcaaa cgaaataccc
    56701 atgagatcga aataggaaaa gaagaagata tcgaaatacg aggacgtcgc ttccgcttct
    56761 atttccaaaa tcgttacaca ttgatctcac tggctgtcga tttattaacc gggattttct
    56821 atatttttgg aagccttgct tccttaacta aaatccccga tcgatatggc acctattttt
    56881 atttggctgg tgctattttc ttgacaattc gtcctattct cagaatcgta aggaacattt
    56941 ttatttacga cgaaaaaaaa caatgaagag aacaagcaaa aaaaagaggc atgagatttg
    57001 aaaaaatctc atgcctcttt tttaacccta tcgtatcact ttgatacaga cgagcggtcg
    57061 tcccactttc ttccttgacc attgtcaaaa atgtccactc gtatcgttca taaaacgtgg
    57121 tatgatctgt aattaaataa agtttttcat acccaagttg atgcattttt tctaatttcc
    57181 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
    57241 agatttggtg tcagatcggg acggttatgg aagtcgtttt caatgacgcc cgctcctccg
    57301 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
    57361 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
    57421 cacttcgcac tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
    57481 accaatgttt aaacctctga ctaaaataaa acgtttacaa aaattataca agtctttatg
    57541 aaaattagca atgacaacaa tagtgatgta aaaaaaaacg gaaaacaatc acttgttctc
    57601 cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat cgtagctacc
    57661 ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc tagtacacca
    57721 cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac ccatggaggc
    57781 ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac actaactaag
    57841 accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat aggtaaccca
    57901 aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt tgttacaacc
    57961 atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc taaagttgca
    58021 cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat aaacggtgcg
    58081 ctatgtccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt gattgtttgc
    58141 atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa tggtgtgata
    58201 aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg ttcttggacc
    58261 actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat tgcagcaact
    58321 aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc ttttgcaact
    58381 gccggtggca caccatcagg cattttgatg atcaattttt catttccgct taaacgtaca
    58441 aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt tgagctcata
    58501 cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc ggaaacaccg
    58561 tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa gacagaaaga
    58621 atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc accaccaaaa
    58681 attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat tactgctaat
    58741 gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc aactaaatgc
    58801 cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa tgcaacaaat
    58861 ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc gacgatacag
    58921 atcaatgatc tcttttgcta aatctgtaaa agctatggat gtcatcagat gatcttgact
    58981 gtggactgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg tcagcatctc
    59041 tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt tttcatctgc
    59101 taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc tttttgcatt
    59161 tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt ccatttattg
    59221 tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg agtacttttt
    59281 caccattcat catgccatag tcagccatat tgattatatc taaaggaatg cctttaggtg
    59341 ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa agtaaaacgt
    59401 ctacattttt agattctagt tgattatccg catctgaagc agatacagca aagatgtctg
    59461 cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga cttgtactca
    59521 ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg ttcctttcta
    59581 tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt aaaaagttga
    59641 tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa agtgcacact
    59701 aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa aaagttgtga
    59761 cacaaaactt gtcacaactt tttttcgaat aaacggtatt caaaagcttg catctgcggt
    59821 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
    59881 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
    59941 attttagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
    60001 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
    60061 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
    60121 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
    60181 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
    60241 caaataacgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
    60301 ctcatccata taccgttctt catgttctct tcccataccg ttttctgtta tcagccaagg
    60361 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
    60421 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
    60481 ttctggatgg aaaggtgtct cttcattcca ttgataacga ggagcgcgaa cgcgtttagg
    60541 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
    60601 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
    60661 gtaccctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
    60721 agctttttgg tcttctggag aattagatcg agcatagacc atttcaggat ttaaaataca
    60781 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
    60841 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
    60901 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
    60961 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
    61021 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
    61081 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
    61141 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
    61201 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
    61261 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
    61321 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
    61381 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
    61441 gatttcctcc tgtttttaga tcccatcatt ttccacacga tttgctactt ttacaaatgg
    61501 cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg caccgatatt
    61561 tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga ccattacaac
    61621 tgctttcgcc gcaaacccta aagcggttgc aaaataacca atcgttcctg tgataagagg
    61681 cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac caaaaataac
    61741 tggttcatta atgttgaaga tcccaggagc aagggataac ttggtgattt gtttcatatc
    61801 ctcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc cagacccacc
    61861 catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt cttttccagc
    61921 ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc gtatcggctt
    61981 caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa acatcaatag
    62041 caaaataccc ggtaaccctt gaacgacacc ttctaatggg cgttgtacga cattgtaaat
    62101 gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag ccgcgatacc
    62161 cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat tcgttggcac
    62221 ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat aaagttcaat
    62281 agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtgtctgtat attgtttagc
    62341 caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa cagttggatt
    62401 aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca ctttattcag
    62461 cttggctaat tcgatcccta ttagaaaaac agcatagatg gtcaagaaac ttagtgtgac
    62521 atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaagt aacttatctg
    62581 tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa aagcacccgt
    62641 aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat accttaaatt
    62701 attgattctc gttgccacgt tccctaaaac tttggctaat ttatccataa aactcattcc
    62761 agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta ttagtcagcg
    62821 cttacatttt ggtgaacaga aactatttac tcctcttttt taccaaatat aaaacaaaaa
    62881 atcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt ttctttttct
    62941 cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat tgcgtcaaac
    63001 gcagcaagta cgttccgcct ttcgatggcc tgaacgatct ctgtatgaat atcgatcgtc
    63061 tcgattttca gatgctggat atcataattt ttattaaaca aagcaatcga ttcattaatg
    63121 attgggataa tatgcagcaa ggctatgttt ccgctagctt ctgcaatcat cgtatgaaaa
    63181 tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc aatcttttgc
    63241 gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc caaacctgcc
    63301 atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg atcctgatct
    63361 tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact gacaaatgtc
    63421 cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac agcttctcgc
    63481 accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg cagtttatct
    63541 cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt tacttctact
    63601 agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt ttttcgtaat
    63661 tattataaca cgtttgaatc atctgatgat tttttgtata aaaaatcgat taatccgttc
    63721 atagacatac aaacgaagaa gatatttacc ataaaaaaga ctaggataaa attcactcct
    63781 agccttcgat catttttatt ttgatcgaca aaaaatatga tgttcaataa cagacgatct
    63841 tcattcgatt cttgatgtca tcttttgttt tttttaatat atggataaaa agtttgatta
    63901 catcgtttct attctagaat ttggtcgatt ctcaattctt cttctggtga gaaatctaaa
    63961 ttatccatca ttcgaacact ttcttgtaac tgacttaacc gacttgctcc gatcagtaca
    64021 cttgtaacag atttttgtcg taaattccat gcaagggcta tttgcgctaa tgattgtcct
    64081 cgtgatacgg cgattgtttg cagtgctttg attttttcca gagttgatcc aacttgttct
    64141 tctgaaagga atggtatttc cttacgatgt gctctagaat cttcaggaat accatgtaga
    64201 taacgatttg tcagcaaccc ttgagcaagc ggactgaacg tgattgcccc tagcccttct
    64261 tcttctaata ctggagatag atcgtcttct agtagtgcac gagaaaacat attgtagcgc
    64321 atctgatgaa taatgaacgg tgcttccttt ctttttaaaa tttcagtcat ttttttgtat
    64381 cttctccatt atagttggat ataccaatat ataatgcttt tccttgtctt acaagttgca
    64441 tcaacgcttc tgctgtttct tccaaaggtg tatcagggtc tgggcgatga tgatagaaga
    64501 tgtcaacata atctagcccc attctttgga aactttggtc acaacttgat atgatggatt
    64561 tacgagagcc ccattcccca tatggccctt cccacatatg ataacctgct ttgctagaaa
    64621 taatcagttc atcacggtag gcttgaaaat cttctctaaa aatacgccca aagtttttct
    64681 ctgcagctcc agcagggcct ccataattat tcgcaaggtc gaaatgggta attcccatgt
    64741 cgaatgcgcc tcttaaaatc tctctttgat tatggatagg atcataatca ccaaaatttt
    64801 gccataatcc gagaggagag ataaaatcgg taatttcaaa cctgaatgac cggatttacg
    64861 atattccatt ttttcataac gtgcactatc tgcaatatac aatttttctc ctcctcatca
    64921 aatcttttta aaacgctttc ttgttttcta tttttagttt actacatttt aaagaaaagg
    64981 agttaatcaa aatgattttt tcgtatattt ttttgccatt tgttttttac tcgttgatag
    65041 atcagaaatt gattacgtgc ttgctggatt tttttatagc gtttcggttg ttttttgtaa
    65101 aattgctgat gatagttttc tgctggccaa aacgtaccgg ctggttcgat ttttgtgacg
    65161 attggttggt ggaaagttcc tgaactgtct agtttctgtt ttgattgttc cgctaattct
    65221 ttttgtcgtt cgtcttgata aaaaatcact ggacgatatt gcttccctct atcttgaaat
    65281 tgtccaaatg tatctgtggg atcagtaatt tgccaataga ttgtcagcaa ctcgctataa
    65341 cttatttctc ttgtgtcata aatgatctcc acagcttcca catgacctgt gtaaccacca
    65401 cttacttgat cataattcgg tttttcaaca tgtccgcccg tgtatcctga caaaacagat
    65461 aggatccctt ttttcgattc aaacggctcg accatacacc agaaacatcc ccctgcaaat
    65521 actgcacgtt cttgatagtc agcatcttgc atggcatgct tggaaaagtc atatttttgc
    65581 tccttatcaa atccttccgt aatcaataaa taaaagtcca ttacatcagg cgtcagattc
    65641 attcggatag ctaatggacg tagtgttact tctagttttg ataactgttc tttaacggat
    65701 atattttctc ttgtgtcatt ctttgtctga atcaatactt ttcgttccca atctcgtgta
    65761 ttcggattca aaatcagatt ataaagtgtt tgaatgaata tttgttcctc atccatagat
    65821 tctcctcctt tccgaagaag acaagctagt gactttagct gtaatttatc ataaagtgag
    65881 gaaataatcg attgaatcgt atttattcaa agaagataag cagcttcaga tgatataaga
    65941 tgatctttat cttaaaaagc atactctatg gtttggttta actaaaaaac gacctctgaa
    66001 aaaagggatg ttctccaatt ctcagaagtc gagtaaagat gattcttttt tatgagcgat
    66061 aataaacttc atccaaaaac agaccttgtg cagggacggt ttctcctgca tgttgccgca
    66121 ctttgctttc aaatatttca tcgattgttt ctatcggcat ggcacctgtg ccgatttcta
    66181 gtaatgtccc catgataatc cgcaccattt tatataagaa tccgtctccg acaaaagtaa
    66241 aatgaagcat ttctcccttt cgttcgatag ataattcatc aatcgtacgc actgtggatt
    66301 tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc
    66361 aagctgcatt cagcttgtcc atatccaact cttgagggaa ataaaagctg tggtttcgct
    66421 caaatgctga aggaatcacg ttgttccaaa cataatagct gtattttttg cccaccgcat
    66481 tatatcttga atggaagcgc tcaggcattt cttcgattct tttgatgaca atatcccgcg
    66541 gaaggtaacg attcataaag tcgatcattt ctgccagtcc aatttctgtg tttgttttaa
    66601 aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt tcttcctgat ccaataattt
    66661 ctatctcttc atttgtcatc tgatgcaata ctttttcgat ttttccttga atggttttat
    66721 cgtcatctcc aagtctttgc catcctgaat atctttttcc gtcatattcg attgtcaact
    66781 tgatgtttct catattttag tggctcctct gtcttccatt tggtcttctc tctacctttt
    66841 taagattgta gcacaaaata tagctccttg cttctctaag acagaagcta tacaagaaaa
    66901 ctgtggaaat atatatttca gaaaaacaaa aaacagccac cggatgaagt atccgctgac
    66961 tgttcaattt gacggctcaa gttttactgt ttgagatgca agatactcaa ccaggcaatg
    67021 ggcacataat taaagaaaaa actgattctt tggcaaaaac ctattttatt cagtaatggc
    67081 caagaattta tagaaggaat tcttgccagt ccataaatcg ccgcaaaaag caaactgatc
    67141 acagacagtc caaggtataa gtggcttacg tccatttgcc cattttttcg atagatcaag
    67201 aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta aacctgatcc gatattatgg
    67261 acccatgtcg agacattcca cgaagattca tgggtattga tactgaacaa acctgtaaag
    67321 atacaatcac ctataccata gaacgcgatg gctgctgtaa ctagggtagc taacacacga
    67381 gatgtactta caaatgcagc atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa
    67441 accacagacc aaataagaaa cgcttttctt acaggactgg aaacctctcc aaatacactg
    67501 atcacgctct tcatttgatc taattcagga taatacaatc ctaatacgta cggagtcaaa
    67561 aaatcactca gcacgcctaa taataaaaag aaaaaaccaa atttacgtaa aaaatccatg
    67621 atacgcctcc aataacaatt acctatgctt ttaattgtta ttataaacga ctttatcttg
    67681 atttaacaga aacctctatt tacacgaaca tctatataac tcattaaaaa ctcgaatcat
    67741 tttaaaaata ctaaatatct aacgttcaac gttcacttaa tccatctaaa caatctttca
    67801 atttgatttt ttccccactt cttttacgcg cgcctagctc tcctattgca gtaaacaaca
    67861 gatcacttga cgaatttaag gcagtttcca ttgaatcctg gataacaccg ataataaatc
    67921 caataccaac gatttgcatc gcgacatcat tagagatacc aaacaaacta catgctaatg
    67981 gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc acaagcagct aaagcagaca
    68041 aaatacataa aaggactttc aaaacaaatg gtgcttcaat ccctaaagaa tgtacagcag
    68101 tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat attgatcgta gcacctaacg
    68161 ggatcgatat ggaataagac tcttttgtca atttcaatct ttcagccaac atcatgttta
    68221 tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac
    68281 aaaagaaaat caatggatag ggattttctt taataaacaa aaacgtgagg aatgggtaca
    68341 caactaatgc gacaaacagc atcgtaccga tcaaaacaag taaaagctgc agatactctg
    68401 ccaatccagc gattccagtc gtagcaattg attgataaac caatcctaaa atccctatcg
    68461 gagcaaatgc aataatcact tgtacgactt gtgacaacgc tatagatatc tgatccacca
    68521 actcttttgt cgattctgaa cgtgctcgaa aagctagtcc caacaataca gcccagaata
    68581 aaacgccaag gtaattcgca tcaataagag attgaacagg attttgtgtg acattcgtca
    68641 acatagtaga taaaacactt tccaaacttt gcggtgcttt ttcagatact gtttcttgta
    68701 aagtaatagg aacagtaaaa attgaactta caatgactgc tacaagtgca gaaagcaatg
    68761 ttcccactaa atataagatc aaaataggct tcacgaatgt cttattccca attttatgct
    68821 tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac
    68881 tgacaaacaa cgtccccaat attgaaataa atgtccacgt ggggaaaaag ataccaaaca
    68941 atattccgac taaaatacca acaacaatac gttgaactaa cgacatatcc aaaaacttct
    69001 ctaacaaatg accacccttt cacaatttta acaatcattg tatcatttta tctaaagaaa
    69061 ctaaaggtgc aattttctaa aaattctaat aatacaattg gcaattcatg ctcttgcaac
    69121 attcaatttt agtattggag ggtttattca atctctaaag aagtcgagag aaaactattt
    69181 atcgttatta ttatagttat ccaagtaaaa cgtaactaag atgaaggacg aaactagaaa
    69241 tttcatcctt catcttaatt cttagacata gcaatcaatt aatattttcc actgagtctc
    69301 ttctttctct cactctcact ggtttactta cccataaacg atttgattaa agccattttt
    69361 caattcatta ttcgctgtct cgttaaagta aagataatta tcgggattcc cctgattttg
    69421 ttgtgtcacc aatacttttg gctgattttg ctgaaacccg aatagataga cgttcttttt
    69481 cagatatggt tctgtctctg catcggaata gacggctgtg atttgatagt ctgcttgacc
    69541 tgtcccactt tctgaccatt ctgcagaaac aggcactcca ccaatagcca tcttccactc
    69601 cccgttcaaa ataacttgag ggactttaag accatataag tccacactca tttgattcgt
    69661 atagcttttg tattgttgtc ccattgtttg gccccatgta gccataaatg cctctaattg
    69721 tgcggatttg tctgcattcc acagtgtttg ttcgacttgt tcgctgcttt ctgaagatga
    69781 agcctctaca gaagaacttg aagtagatgt ttgagttgtt tcagtcgttt tggaagactc
    69841 tgacgaagta gaggtatctg ctgtttccgt acttgctgca gttggcttgc tctctgtgct
    69901 agttgttgta gtagttgcaa ttgttgcttt cgctgtttct tttgttgatt cttttttcga
    69961 ttcattcccg ttggtacaac cagctaacaa aaaagctaga ccaattgtta ctaaaatcct
    70021 ttttttaaat taaaaaactc ctttcgatta ctcccacttc tttattctat caaataagca
    70081 atgtgatttt attgattttt tgtattttct catccatctt ttaaaccttt taaaaactaa
    70141 gaagcacccg ctgatgttgt ctgtaataca tcagcgggtg cttcttttat tttaatcttc
    70201 gtgattttcc aatttacctc acgctttata tttgtatttg aagaaacata gacttttagt
    70261 catcatcgtc ttcctcatcc aaatcttgtc ggacagtttt tccttggagt ctttgtactt
    70321 ggtagatgat ttctttattg aaacttaaaa gttcaacaag caattgtttc aagccatatt
    70381 tttcttcttt ttcagctaat ttgattgccc gtgtgataaa gacattttgg aaatcaaaat
    70441 cttttgcaaa gttttccaac attgttgagg ctggtaaata tttgttttga ccatgttcgt
    70501 aaatttttcc ataacgcatg acttcttcta aagtagacgg aacgatttca ttttcaatca
    70561 ctaactcatg agagatttta ttgaaccatc tcgcttcttg atcagcatat tctgaaaaaa
    70621 gggtacttaa ttcttgcgaa gatgtaccca aaacatacaa ttgtgcttgg atcaatttca
    70681 tttcttctaa tttaaaattt gccaatacat gccccaccat ggcgccagca gttggtttat
    70741 gatgatcgat atctgcttgt tttgtttctt gagcaaattt ttcttccact atattcactg
    70801 atttacgcct cttttacttt tgttgattgg acttcataac ctaatttttc cacaactgca
    70861 gctaattgtt cagggtggac ttcatctgga tcaaagtttg ctttgatttt gctcgcatta
    70921 aacaaaactt tcgtattgct taccccaggc tgttgagaaa ccgcatgttc tattttttgc
    70981 atacagcttg gacaagctag tgtatctaat tgcataatca tttttttcat cgtagttctt
    71041 ccttcctttt tcttgatagt cttattctag attacagctt ccataaaaaa attgattctt
    71101 atcaagtttt acgatttttc ttctttgctt tcgtgtccaa aatacaataa acgcatcgcg
    71161 ttaaagataa cgatcaagat actagcttcg tgaacgaaca tcccactagc catgtaaata
    71221 aacccggcaa ataagccgat gagtaaaaat aagacgacac caatggcaat cactacattt
    71281 tcacgggtat tcaaaacagt tttcttagcc aaacggtaag catgaaccaa cgatccaaaa
    71341 ctagattgca tcaagacaac gtcactcgtt tcgatagcga catccgttcc tgatcccata
    71401 gcaatcccga tatcagccgc agccaaagag ggagaatcat tgattccatc tccaatgaaa
    71461 gcaacgtgca atccttgttc ttggtatttt ttcacaaatt gaaccttttc atctggcaat
    71521 aattcagcat ggacttcatc aatgcctaac atatcagcta cataatcagc agtcatctga
    71581 ttatcacctg tcagcatcac taaatgtttt gctcctgctt gtttcaacat agctaattgt
    71641 tcagcgactt ctggtcgaat cacatctgac acaccaatga tttgagtgat ttttttgtcg
    71701 attgctacaa taatgactga gctgcctctt tgttgtaatt gatgtaaatc ttgtacttgc
    71761 tttggtgtga gagaaagttt gtgagcggca atcaatttgg tgttgcccgc acaaactgta
    71821 tgaccatcaa tctcagctgt gattccttgt cccttgatcg tctgattatc tttgactgct
    71881 aattgttgaa aatcaatgtc tttctcctga gcataatgga tcacggcgcg ccccagagga
    71941 tgatcggata acgtttctaa tcgagccact aaagctaagc tgtccccttc atcctctgta
    72001 tagttcttga tagtggatac agcagtagtt cctttggtca atgtaccggt tttatcaaag
    72061 acaaaagtat cgattttgga aaaagtatcc attgcttcac cgcctttgac taagatgccc
    72121 cgtttcgctc cattaccgat tcctgctaca ttcgaaacag gcgcaccaat gactaaagcg
    72181 ccaggacaac caagaaccaa aacagtgatg gctaaacgaa aatcacgact gatcagacca
    72241 acaagcaacg caataagtaa aacggttgga gtataatact gagaaaattg atcaatgaat
    72301 ttttccgcat gtgatttggt atcttgtgct tcttcgacta attctataat tttggcaaag
    72361 gtcgtatcat ctccgacctt agttgcttcg atcgtcacgt agccatctgc taaaatcgtt
    72421 ccagaaaata cgttatctcc actgattttg acgacttgtc gtgattcacc cgtcactgcg
    72481 gcttcatccg catacccttt cccgtcaatg actcgtccgt ccacaggaat agctccacca
    72541 gtttttacta agacgatatc gccttcttcc acgtcatcga tttccacttc ttcggtcgtt
    72601 ccatcttctt ggacaacgct ggcagtcgat ggggccatct cggtcaaagc cttgattgat
    72661 tcccgcgttt tggtcaatgt tttttgttcc agataactac caaacaaaaa caagaatgta
    72721 acgatagctg actccttgta ttctccgatc ataaaggcac caagcacagc aatagtaacg
    72781 agtaaatcaa ttgagataac tttgactttt actgcctgat acgcatggat tataataggt
    72841 atgaccgcaa taatagaagc tatggctaga gcaatgttat agaacaagac aaatccagta
    72901 aatttcccga taaaaccaaa aataatcaac acagctgata aggcggtgat atgatttcga
    72961 tgctcttgga tccacttttg taatttcatc tttctccctc ttttcctttt cattcttacg
    73021 agactaagta tagatactta tccatcataa aaaattgacc actatcaagt ttattcaaaa
    73081 aggcggtttt cttttggtat actgaattcc tacagtcatt aaacgatcat atagaaaaag
    73141 gaagcgccga aacgcttcct taggtagttc tattttttta ttcaaagata agatgctttg
    73201 tcatcttacg actgaagaac aacaatcaaa aaagggcagc agccactcat tcacaagaaa
    73261 tatcgttttt tgatatggga attgaagcag tggacaaata tctctactta ttagctggga
    73321 ataagatcca aaaaagctta atggatttta tccaagaatt ggaatgtact ttccacaaaa
    73381 aattcactca ttccattctt ttaaaacttt tgattcatac agcgtgtcta attgagcgta
    73441 cattgataaa cggtcatgaa cttaaaatta tatcagaaga tgacacaaga ccttctcatg
    73501 aaacaatttt tcatgtaaaa aaggccttca aaaatattga aacagaattt gggatcactg
    73561 tttcttatga tgaatgtttc tttatctatg atattatcgc atctaaataa tcttttttta
    73621 tgtaaacgag tattttttta acttattgtt taagagtgat acgcgaattg taaaattaag
    73681 ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt atttccgacg aaagaaaaca
    73741 aaggagtgt
//
LOCUS       DAIGQM010000003        72433 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.003, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000003 DAIGQM010000000
VERSION     DAIGQM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.003"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(159..443)
                     /locus_tag="NOA48_000133"
     CDS             complement(159..443)
                     /locus_tag="NOA48_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788437.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(461..1351)
                     /locus_tag="NOA48_000134"
     CDS             complement(461..1351)
                     /locus_tag="NOA48_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCI0788438.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1371..1589)
                     /locus_tag="NOA48_000135"
     CDS             complement(1371..1589)
                     /locus_tag="NOA48_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCI0788439.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1559..3259)
                     /locus_tag="NOA48_000136"
     CDS             complement(1559..3259)
                     /locus_tag="NOA48_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCI0788440.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3526..4299
                     /locus_tag="NOA48_000137"
     CDS             3526..4299
                     /locus_tag="NOA48_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788441.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOA48_000138"
     CDS             complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOA48_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCI0788442.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5015..5117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5123..6094)
                     /locus_tag="NOA48_000139"
     CDS             complement(5123..6094)
                     /locus_tag="NOA48_000139"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0788443.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOA48_000140"
     CDS             complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOA48_000140"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCI0788444.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOA48_000141"
     CDS             complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOA48_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCI0788445.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9049..9873)
                     /locus_tag="NOA48_000142"
     CDS             complement(9049..9873)
                     /locus_tag="NOA48_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0788446.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9846..10526)
                     /locus_tag="NOA48_000143"
     CDS             complement(9846..10526)
                     /locus_tag="NOA48_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0788447.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10549..11487)
                     /locus_tag="NOA48_000144"
     CDS             complement(10549..11487)
                     /locus_tag="NOA48_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCI0788448.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11732..12595)
                     /locus_tag="NOA48_000145"
     CDS             complement(11732..12595)
                     /locus_tag="NOA48_000145"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCI0788449.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOA48_000146"
     CDS             complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOA48_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0788450.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFLSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15451..16257
                     /gene="proC"
                     /locus_tag="NOA48_000147"
     CDS             15451..16257
                     /gene="proC"
                     /locus_tag="NOA48_000147"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCI0788451.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOA48_000148"
     CDS             complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOA48_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCI0788452.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOA48_000149"
     CDS             complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOA48_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCI0788453.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19461..20702)
                     /locus_tag="NOA48_000150"
     CDS             complement(19461..20702)
                     /locus_tag="NOA48_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCI0788454.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOA48_000151"
     CDS             complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOA48_000151"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCI0788455.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21729..22652)
                     /locus_tag="NOA48_000152"
     CDS             complement(21729..22652)
                     /locus_tag="NOA48_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788456.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23391..24677)
                     /locus_tag="NOA48_000153"
     CDS             complement(23391..24677)
                     /locus_tag="NOA48_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0788457.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24670..25938)
                     /locus_tag="NOA48_000154"
     CDS             complement(24670..25938)
                     /locus_tag="NOA48_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0788458.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26190..26651
                     /gene="mscL"
                     /locus_tag="NOA48_000155"
     CDS             26190..26651
                     /gene="mscL"
                     /locus_tag="NOA48_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCI0788459.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26710..27156)
                     /locus_tag="NOA48_000156"
     CDS             complement(26710..27156)
                     /locus_tag="NOA48_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0788460.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27249..27494)
                     /locus_tag="NOA48_000157"
     CDS             complement(27249..27494)
                     /locus_tag="NOA48_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCI0788461.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27609..28187)
                     /locus_tag="NOA48_000158"
     CDS             complement(27609..28187)
                     /locus_tag="NOA48_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0788462.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28264..28794)
                     /locus_tag="NOA48_000159"
     CDS             complement(28264..28794)
                     /locus_tag="NOA48_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCI0788463.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="NOA48_000160"
     CDS             complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="NOA48_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCI0788464.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29651..30046)
                     /locus_tag="NOA48_000161"
     CDS             complement(29651..30046)
                     /locus_tag="NOA48_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCI0788465.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30043..31455)
                     /locus_tag="NOA48_000162"
     CDS             complement(30043..31455)
                     /locus_tag="NOA48_000162"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCI0788466.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="NOA48_000163"
     CDS             complement(31452..31988)
                     /gene="cysE"
                     /locus_tag="NOA48_000163"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCI0788467.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32074..32313)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32310..33770)
                     /locus_tag="NOA48_000164"
     CDS             complement(32310..33770)
                     /locus_tag="NOA48_000164"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCI0788468.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33940..35097)
                     /locus_tag="NOA48_000165"
     CDS             complement(33940..35097)
                     /locus_tag="NOA48_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCI0788469.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35131..36501)
                     /gene="radA"
                     /locus_tag="NOA48_000166"
     CDS             complement(35131..36501)
                     /gene="radA"
                     /locus_tag="NOA48_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCI0788470.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36564..37091)
                     /locus_tag="NOA48_000167"
     CDS             complement(36564..37091)
                     /locus_tag="NOA48_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCI0788471.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37321..38127
                     /gene="proB"
                     /locus_tag="NOA48_000168"
     CDS             37321..38127
                     /gene="proB"
                     /locus_tag="NOA48_000168"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCI0788472.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38124..39371
                     /locus_tag="NOA48_000169"
     CDS             38124..39371
                     /locus_tag="NOA48_000169"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCI0788473.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39447..39791
                     /locus_tag="NOA48_000170"
     CDS             39447..39791
                     /locus_tag="NOA48_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788474.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39908..40234)
                     /locus_tag="NOA48_000171"
     CDS             complement(39908..40234)
                     /locus_tag="NOA48_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788475.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40607..41808)
                     /locus_tag="NOA48_000172"
                     /pseudo
     CDS             complement(40607..41808)
                     /locus_tag="NOA48_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41925..42440
                     /locus_tag="NOA48_000173"
     CDS             41925..42440
                     /locus_tag="NOA48_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0788476.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42639..43085)
                     /locus_tag="NOA48_000174"
     CDS             complement(42639..43085)
                     /locus_tag="NOA48_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0788477.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="NOA48_000175"
     CDS             complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="NOA48_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0788478.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44964..45593)
                     /locus_tag="NOA48_000176"
     CDS             complement(44964..45593)
                     /locus_tag="NOA48_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0788479.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45577..46041)
                     /locus_tag="NOA48_000177"
     CDS             complement(45577..46041)
                     /locus_tag="NOA48_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0788480.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46528..47796)
                     /locus_tag="NOA48_000178"
     CDS             complement(46528..47796)
                     /locus_tag="NOA48_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0788481.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48027..48764)
                     /locus_tag="NOA48_000179"
     CDS             complement(48027..48764)
                     /locus_tag="NOA48_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0788482.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48831..49400)
                     /locus_tag="NOA48_000180"
     CDS             complement(48831..49400)
                     /locus_tag="NOA48_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0788483.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49528..50400
                     /locus_tag="NOA48_000181"
     CDS             49528..50400
                     /locus_tag="NOA48_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0788484.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50742..51614
                     /locus_tag="NOA48_000182"
     CDS             50742..51614
                     /locus_tag="NOA48_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0788485.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51611..53569
                     /locus_tag="NOA48_000183"
     CDS             51611..53569
                     /locus_tag="NOA48_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0788486.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53820..54671)
                     /locus_tag="NOA48_000184"
     CDS             complement(53820..54671)
                     /locus_tag="NOA48_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0788487.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54794..55261
                     /locus_tag="NOA48_000185"
     CDS             54794..55261
                     /locus_tag="NOA48_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI0788488.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55524..56006)
                     /locus_tag="NOA48_000186"
     CDS             complement(55524..56006)
                     /locus_tag="NOA48_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI0788489.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56106..56969)
                     /locus_tag="NOA48_000187"
     CDS             complement(56106..56969)
                     /locus_tag="NOA48_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0788490.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57567..58415
                     /locus_tag="NOA48_000188"
     CDS             57567..58415
                     /locus_tag="NOA48_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788491.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58586..58927)
                     /locus_tag="NOA48_000189"
     CDS             complement(58586..58927)
                     /locus_tag="NOA48_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI0788492.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59013..59720
                     /locus_tag="NOA48_000190"
     CDS             59013..59720
                     /locus_tag="NOA48_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0788493.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59707..60030
                     /locus_tag="NOA48_000191"
     CDS             59707..60030
                     /locus_tag="NOA48_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0788494.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60119..61156)
                     /locus_tag="NOA48_000192"
     CDS             complement(60119..61156)
                     /locus_tag="NOA48_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0788495.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61603..62586)
                     /locus_tag="NOA48_000193"
     CDS             complement(61603..62586)
                     /locus_tag="NOA48_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCI0788496.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63002..63772)
                     /locus_tag="NOA48_000194"
     CDS             complement(63002..63772)
                     /locus_tag="NOA48_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788497.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63765..64700)
                     /locus_tag="NOA48_000195"
     CDS             complement(63765..64700)
                     /locus_tag="NOA48_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788498.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65294..66943)
                     /locus_tag="NOA48_000196"
     CDS             complement(65294..66943)
                     /locus_tag="NOA48_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0788499.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67138..68034)
                     /locus_tag="NOA48_000197"
     CDS             complement(67138..68034)
                     /locus_tag="NOA48_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0788500.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68027..68707)
                     /locus_tag="NOA48_000198"
     CDS             complement(68027..68707)
                     /locus_tag="NOA48_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788501.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68708..69490)
                     /locus_tag="NOA48_000199"
     CDS             complement(68708..69490)
                     /locus_tag="NOA48_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788502.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69483..70400)
                     /locus_tag="NOA48_000200"
     CDS             complement(69483..70400)
                     /locus_tag="NOA48_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0788503.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70403..70687)
                     /locus_tag="NOA48_000201"
     CDS             complement(70403..70687)
                     /locus_tag="NOA48_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788504.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71388..72008)
                     /locus_tag="NOA48_000202"
     CDS             complement(71388..72008)
                     /locus_tag="NOA48_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788505.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72089..>72433)
                     /locus_tag="NOA48_000203"
     CDS             complement(72089..>72433)
                     /locus_tag="NOA48_000203"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788506.1"
                     /translation="SNIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQD
                     KKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQK
                     KRDNNDQYLPKK"
BASE COUNT        20831 a        15443 c        12751 g        23408 t
ORIGIN      
        1 ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga
       61 attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat
      121 tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa
      181 gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct
      241 acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg
      301 ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca
      361 aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg
      421 aacgttacgt cataatattt cattatctct acctctttcg tcattcaata ttttgtactt
      481 gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg
      541 catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta
      601 attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg
      661 ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca
      721 acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta
      781 tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt acttctttga
      841 attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg
      901 cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca
      961 tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg aagcgttccg
     1021 ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca
     1081 attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc
     1141 caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa
     1201 gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta
     1261 gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga
     1321 tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt
     1381 tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt
     1441 ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg
     1501 actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct
     1561 acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata
     1621 ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt
     1681 ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct
     1741 ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat
     1801 catccggcat actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat
     1861 agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc
     1921 atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc
     1981 ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc
     2041 agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta
     2101 atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa
     2161 aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg
     2221 gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg
     2281 ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt
     2341 tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc
     2401 aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg
     2461 gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat
     2521 ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg
     2581 ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag
     2641 ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt
     2701 ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga
     2761 taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac
     2821 cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt
     2881 gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag
     2941 attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc
     3001 gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat
     3061 ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag
     3121 cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa
     3181 atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt
     3241 aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa
     3301 aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct
     3361 cctttaaata aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat
     3421 gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat
     3481 gttgtaaaat aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt
     3541 tatgtacata ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac
     3601 tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct
     3661 gctggagaat atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag
     3721 cgtttctttt cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt
     3781 actgatttaa cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt
     3841 ggtcatatga aaacacatct tcattcgccg tttttttata aactacagaa taattttgta
     3901 tacttcgatc ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat
     3961 aggatttttg ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct
     4021 tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt
     4081 aatttgatgc aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa
     4141 tatcgtatcc caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat
     4201 cgagaagagg aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg
     4261 gtagaagatg ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat
     4321 aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt
     4381 tacagctcct gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat
     4441 aaaacgatga tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa
     4501 aagagccaag gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata
     4561 aaatgccaaa aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta
     4621 atttgtttcg tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct
     4681 gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa
     4741 taaacttgtc ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc
     4801 tttgtccctc ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa
     4861 ctgctgccga tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt
     4921 ccttctaccc aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc
     4981 acaaaggagg aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc
     5041 tcgcataacc gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga
     5101 ctcccctttg tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt
     5161 tgttttcatg gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga
     5221 ttttgtcgat tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga
     5281 tagctgaatc ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag
     5341 catacacact agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg
     5401 ctgtatcgat catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat
     5461 tcattacttc tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt
     5521 tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga
     5581 caacatcatc gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca
     5641 tcaaatgatc gactggaata tcaaagaaac cttggatttg aactgcatga aggtccaaag
     5701 tcagcattct tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg
     5761 gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt
     5821 tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt
     5881 tatcattgac tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt
     5941 cttcaatgtt tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact
     6001 cgacgccgac tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa
     6061 tttttaatct tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa
     6121 ctctagaatt ctacctaata aatagtagtc ataattttta aataaatcaa gtgattttgc
     6181 aaaagtctta gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg
     6241 ctctcgcaat tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa
     6301 tcgaactgtt tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc
     6361 tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac
     6421 cacatccgac attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga
     6481 ctttagttcc tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt
     6541 tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct
     6601 tgacatggct gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt
     6661 ctacgatttt tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga
     6721 tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg
     6781 tcgttgctga atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc
     6841 tcatgatctc atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa
     6901 aatcatccgt ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat
     6961 ctgttagata gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca
     7021 aagcttcgtt gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg
     7081 gtgttgcatc tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc
     7141 gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc
     7201 cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac
     7261 tgataactaa cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat
     7321 gtcctgttcc caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt
     7381 taacttgttc tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga
     7441 cccgattaat gatatgttct accataggtt taccagaaac gggatgtaaa actttatata
     7501 attttgactt catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca
     7561 actgcgtcac tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt
     7621 caacaaaaca agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc
     7681 ataacgggcc tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca
     7741 cactactcat aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa
     7801 acggtaggct tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc
     7861 tcaataaacg gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca
     7921 ggacgctgat ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa
     7981 gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa
     8041 ctaagcagct ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata
     8101 tttttcgttt gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg
     8161 cgatgaccgt tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat
     8221 tcttcaatca agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact
     8281 acaaggacac gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt
     8341 tcagaagatc cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc
     8401 cggcgtacaa taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg
     8461 ccttttgtgg ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg
     8521 attcttccaa cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat
     8581 cctcctggaa gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt
     8641 ttcgcctctt catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt
     8701 gtttccaagg ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca
     8761 ctgatagaag atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca
     8821 tgcgggtgat tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc
     8881 acctattcca actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa
     8941 aaattcgagc attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga
     9001 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
     9061 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
     9121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
     9181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
     9241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
     9301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
     9361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
     9421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
     9481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
     9541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
     9601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
     9661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
     9721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
     9781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
     9841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
     9901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
     9961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
    10021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
    10081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
    10141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
    10201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
    10261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
    10321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
    10381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
    10441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
    10501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
    10561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
    10621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
    10681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
    10741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
    10801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
    10861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
    10921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
    10981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
    11041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
    11101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
    11161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
    11221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
    11281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
    11341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
    11401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
    11461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
    11521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
    11581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
    11641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
    11701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
    11761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
    11821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
    11881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
    11941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
    12001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
    12061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
    12121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
    12181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
    12241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
    12301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
    12361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
    12421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
    12481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
    12541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
    12601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
    12661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
    12721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
    12781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
    12841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
    12901 cagacaggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
    12961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
    13021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
    13081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
    13141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
    13201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
    13261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
    13321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
    13381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
    13441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
    13501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
    13561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
    13621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
    13681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
    13741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
    13801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
    13861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
    13921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
    13981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
    14041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
    14101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
    14161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
    14221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
    14281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
    14341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
    14401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
    14461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
    14521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
    14581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
    14641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
    14701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
    14761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
    14821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
    14881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
    14941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
    15001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
    15061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
    15121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
    15181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
    15241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
    15301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
    15361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
    15421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
    15481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
    15541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
    15601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
    15661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
    15721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
    15781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
    15841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
    15901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
    15961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
    16021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
    16081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
    16141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
    16201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
    16261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
    16321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
    16381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
    16441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
    16501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
    16561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
    16621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
    16681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
    16741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
    16801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
    16861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
    16921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
    16981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
    17041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
    17101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
    17161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
    17221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
    17281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
    17341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
    17401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
    17461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
    17521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
    17581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
    17641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
    17701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
    17761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
    17821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
    17881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
    17941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
    18001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
    18061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
    18121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
    18181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
    18241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
    18301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
    18361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
    18421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
    18481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
    18541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
    18601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
    18661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
    18721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
    18781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
    18841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
    18901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
    18961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    19021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    19081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    19141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    19201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    19261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    19321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    19381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    19441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    19501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    19561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    19621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    19681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    19741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    19801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    19861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    19921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    19981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    20041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    20101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    20161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    20221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    20281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    20341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    20401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    20461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    20521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    20581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    20641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    20701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    20761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    20821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    20881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    20941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    21001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    21061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    21121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    21181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    21241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    21301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    21361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    21421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    21481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    21541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    21601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    21661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    21721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    21781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    21841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    21901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    21961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    22021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    22081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    22141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    22201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    22261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    22321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    22381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    22441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    22501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    22561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    22621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    22681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    22741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    22801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    22861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    22921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    22981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    23041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    23101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    23161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    23221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    23281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    23341 tactacaagt ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt
    23401 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
    23461 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
    23521 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
    23581 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
    23641 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
    23701 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
    23761 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
    23821 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
    23881 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
    23941 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
    24001 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
    24061 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
    24121 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
    24181 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
    24241 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
    24301 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
    24361 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
    24421 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
    24481 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
    24541 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
    24601 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
    24661 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
    24721 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
    24781 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
    24841 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
    24901 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
    24961 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
    25021 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
    25081 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
    25141 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
    25201 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
    25261 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
    25321 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
    25381 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
    25441 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
    25501 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
    25561 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
    25621 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
    25681 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
    25741 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
    25801 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
    25861 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
    25921 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
    25981 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
    26041 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
    26101 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
    26161 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
    26221 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
    26281 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
    26341 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
    26401 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    26461 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    26521 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    26581 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    26641 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    26701 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    26761 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    26821 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    26881 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    26941 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    27001 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    27061 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    27121 tgacaattct tcaaatttct ttacctgata ttccaccaag caaacgcccc ctgctttttt
    27181 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg
    27241 tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct
    27301 gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat
    27361 actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc
    27421 tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct
    27481 aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt
    27541 caagtttacc ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt
    27601 tttctaaatt attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc
    27661 ccgtaagcgc tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa
    27721 tcaacgcctt gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg
    27781 caattttcga ttgcttcttt taataaaaga tgctgaatcg ctaaaggttc ttgcaatgtg
    27841 atctctgcta aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct
    27901 ttttgatcac gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt
    27961 ataatgcttt tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat
    28021 gcctgatata aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa
    28081 taataggtgt ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat
    28141 gcttcttcgt caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc
    28201 cataaattcg tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat
    28261 atgttattta ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc
    28321 ttcattccat ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc
    28381 tattgttttt tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc
    28441 tccttgggaa aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt
    28501 caaacggtca ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc
    28561 tttcgtaaaa acaacatcca actggtattt cttataattt tgttggatgc ccggaactag
    28621 ttgggcatcg aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg
    28681 atgtaaaaga gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc
    28741 cggccacgaa ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta
    28801 ctccccctga cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt
    28861 taagctctgg acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa
    28921 tcctggactc attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt
    28981 ccatttttgg aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt
    29041 gagctgttgc acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc
    29101 cccagtggaa gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat
    29161 cacaccatcg acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc
    29221 ttcgatgcta tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat
    29281 cagttggtca agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac
    29341 gccgtgatcg ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg
    29401 ttcacgtgcg atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa
    29461 gagtttattc cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa
    29521 attatcttct aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt
    29581 tttatttgaa tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt
    29641 tgttctttct ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt
    29701 ccatccgctc ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg
    29761 cgacccgata cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc
    29821 ctctgcgata ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa
    29881 tcaaaaaggc ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg
    29941 gttttgtttc tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc
    30001 caacataagc caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca
    30061 tcgggttcct tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat
    30121 ttcgtcgctt cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg
    30181 ttcaatctct tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca
    30241 ttgcgagaat aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag
    30301 ataagtgttc agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa
    30361 atcatcgtcc atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc
    30421 cgcatcatct gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt
    30481 attcttcagt cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat
    30541 cggacgacgg tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt
    30601 gatcatttca tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc
    30661 gccaatcgtt acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc
    30721 ttcactttgt gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg
    30781 gatatcgatc gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc
    30841 gggacgtcct ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca
    30901 taaagcgaaa tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc
    30961 tccgacttcc agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg
    31021 ggtacggtaa tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg
    31081 aataaatgct aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggctc
    31141 gacattcaac gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg
    31201 tgctgtaata cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt
    31261 cgatacgaaa tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc
    31321 aatggtgcta cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata
    31381 cataccgaca tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt
    31441 gtagattttt atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct
    31501 ggtactccta ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg
    31561 attttggcgt tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg
    31621 gctccttgtt taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt
    31681 acgccatgga ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc
    31741 attccatggt cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca
    31801 gttaggaaac gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat
    31861 aaaaaatgag agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc
    31921 tcagctgtcg aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac
    31981 caactcatga ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa
    32041 agaaaagaag cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca
    32101 cttttcttca taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta
    32161 ctttgtttcc tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga
    32221 ggcatttcgg caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc
    32281 agctgcttac ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat
    32341 gatttttcac gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct
    32401 gatacagcta cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga
    32461 acagctttga tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt
    32521 gctttgaatg cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct
    32581 tcattcaata caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca
    32641 tagctcattt gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca
    32701 tctgggtttt ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat
    32761 gcatctagat ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg
    32821 aaagctgcgg gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt
    32881 tcgaagattt cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt
    32941 gcatctggta gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca
    33001 cgtttgctta gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt
    33061 ggtggtgtcc agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg
    33121 tcatctccac gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa
    33181 ttataagttg gcataccatc gcgtttttgt atgacaaagt cgccaccgat attatcggat
    33241 tcgaacgaaa tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca
    33301 cggaaacgta caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc
    33361 aagttcgcac atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt
    33421 tctgcttcta attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc
    33481 tgatcaatca gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct
    33541 ccaggatttt caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg
    33601 cttttttcgc catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag
    33661 tctccatcat tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata
    33721 tgcaggtgcc cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc
    33781 ttctttcaaa ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata
    33841 tcatttattt aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca
    33901 actggttgaa tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt
    33961 tttctctgtc tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat
    34021 catgcgtcca gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat
    34081 gtaatgctgt ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg
    34141 ttggcgttct gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac
    34201 tggttttacg gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga
    34261 gactttattc aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt
    34321 gatcaatttg ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga
    34381 tataccctct tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg
    34441 tttcaaacta tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat
    34501 catcaaggtt ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat
    34561 cacgcttgta tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag
    34621 ttgactctca acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac
    34681 tttcttccat tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat
    34741 catcagtaaa atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt
    34801 cgagatcaca acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata
    34861 agtcaagctg acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt
    34921 ggccaacagc aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt
    34981 attattcagc catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga
    35041 aatacccaag cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt
    35101 ttttcctccg tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc
    35161 caaagttgct actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt
    35221 tttaggtagg tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat
    35281 atgactgaca cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg
    35341 ctgtgttcct ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc
    35401 tggttcattt aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag
    35461 caacccagct cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc
    35521 tgttgttgtt cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac
    35581 caaaattgga cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag
    35641 gcgttcttct aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat
    35701 ttcaaaaatc ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg
    35761 aaaactatga tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat
    35821 tcttgggccg gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc
    35881 atttgtttta gcgattttga gtagttctgc agtggtttct cttacttggc tgacacttcc
    35941 tgccacactt gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc
    36001 aggggagata tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata
    36061 aaattctgtg ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc
    36121 ttcgccggat acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa
    36181 cagcaaagtg gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac
    36241 cacacctccg cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt
    36301 tttagggacg acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg
    36361 agttctgcgg tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca
    36421 atttgggcag cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg
    36481 tacttttgat ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat
    36541 caagcttaag tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga
    36601 gcagtcgttt gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc
    36661 tcgccttttt tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg
    36721 ccttcatttg cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac
    36781 actaaaaacc gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct
    36841 cccatgtaag ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct
    36901 gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc
    36961 cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt
    37021 gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct
    37081 ctttttctca ccggttttcc tccctaaata aactactcct attctaacat atccgaggct
    37141 gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa
    37201 ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta
    37261 ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac
    37321 atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg
    37381 atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct
    37441 gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt
    37501 atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg
    37561 gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa
    37621 cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat
    37681 gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac
    37741 gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg
    37801 tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac
    37861 gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat
    37921 aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc
    37981 ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt
    38041 ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt
    38101 actttattta aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag
    38161 atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa
    38221 tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag
    38281 aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg
    38341 agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg
    38401 gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc
    38461 cactaggcgt gaccggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta
    38521 gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct
    38581 cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt
    38641 atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga
    38701 cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag
    38761 aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata
    38821 aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat
    38881 ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc
    38941 cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt
    39001 tagaatatct agagacggct gctttagcag aagacacaga ttgggatact gaatatctag
    39061 attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc
    39121 ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt
    39181 tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg
    39241 gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg
    39301 gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa
    39361 tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg
    39421 ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc
    39481 ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat
    39541 tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg
    39601 ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag
    39661 cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga
    39721 ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga
    39781 ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg
    39841 ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg
    39901 cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt
    39961 caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt
    40021 ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag
    40081 ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt
    40141 tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg
    40201 tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta
    40261 aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg
    40321 aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac
    40381 tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc
    40441 ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaaaagctt
    40501 gcatctgcgg taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg
    40561 ttcttatgac ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat
    40621 ttgtagcaaa ataattacgg tgataaatga tacaacatac actgataaga acaatggcac
    40681 ctgcaaaata aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg
    40741 gtgctaaagc tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt
    40801 gcagacctgg tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa
    40861 atcctgctaa cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata
    40921 acagcaaaca aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact
    40981 tccgctcaag agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa
    41041 aaaatacaaa accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa
    41101 gtaaagtaaa gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat
    41161 gattgcttaa cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt
    41221 caggtaaaag taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa
    41281 atggataacg ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc
    41341 cgcagccaag tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac
    41401 tgacgatcgt tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac
    41461 gtaacccaat cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga
    41521 tgataaacaa tcctgtcatc aatgtttttt caaaccgatc cgactagata agaaacctgt
    41581 aaatagcatc accacaccag tgactaacat gtaactagta aataacaggg tcgtttcagc
    41641 tggcgtagcg tttaactgtg cagcaatcgt ttttaagatt gggtctacta gacccactcc
    41701 cataaaagcg atcatacagg tagctgctac aactagcgct gaacttttcc cctttgtttc
    41761 ttcatttgtt tgttcttgta tatctatttg attctccaat atttccatcc ctttctctct
    41821 attagcatca tacatgattt attttacatg taaatatgca catgtaaaac gtggaaactt
    41881 tactgtgata taataaagaa aataagacga gaggtaggat ttttatgaat actttagcct
    41941 atatattatt atgcgtgctt ttatccaaac cacgttctgg gtatgaattg aagcagctga
    42001 tcacaatttt ttgggaagcc catcacagtc agatctatac aacgcttgcc aagttagacc
    42061 agcagggtta tgtgaccgtt ttggacaaag acgagcactc tcaaaaaaag atctaccact
    42121 tgactgatga aggacgtgct cttgtagagg aatggatcaa agaggaaact cccgctccta
    42181 cgcaaaaaga tgaatttcta gcaaaaatct atgctttttc gacgctcgat aaaacaacag
    42241 ctactggact gctattcact agagaacaac agctgaacaa aatcatgcaa aaaaatcaaa
    42301 aaaaattgaa tgacctctcg ctagacaaga aacaagaatt tggacgttat gttgtgatcc
    42361 agcgcagaat tatgctttgt cagcaggaac tccaatggtg tcagcaagta agagaacaaa
    42421 tgcagcagtt ttttgagtaa gggataaaca gaacctttct agaaatatct attgaagagc
    42481 aaattatctt caataaaaga gcaatacagt tggaaaagaa aaagcgatcc gaacgacagg
    42541 ccaaaaccta tcgttcggat cactattttt ctagaactgc attcaagaga ctatgacaaa
    42601 aagcatgcca aggccttttt tcaaataaca gtgttccatc attcattact ttgaattgct
    42661 tttagcacac ttcttgaaag cgggccaacg atgatcaact gcaacggtaa agcggcaatc
    42721 acattcattt tccaagcatt catataagca gagaataatt gatcaggtat tccttgttcc
    42781 atgatcacac cgaataaaga catacatgtc accattccta aaaccatcaa gcatgaaata
    42841 gttaagatca tttggacctt gctttctgga tttactggta gtttaaaggc aatttttttc
    42901 gccagcacac cgatgatgaa gacatccaaa atgaaagcca ccacgaatcc aggcactaga
    42961 ccaatcaaca aacttgataa atgaagatct tgatgcagcc ataaattata cgcgctcatc
    43021 cccaagacca tcaaaaaaca catcattgtt gtaaaaatta ttccttcttt tttatttgta
    43081 ggcaatctgt accactcctt taaatttgtc acgaaaatca tcgtagcaca tttaaaaatt
    43141 tctcgtaagt acttttttta ttttctgccc ttttatttca taaacttcat cagccgtacg
    43201 ctcgacaaag taagaatcat gagaagtaaa caaaatcgtt cccggatata tttgcattag
    43261 cttctctaaa gcttcgatcg ttgccatatc aataaaatta gtcggttcat ctaacagcaa
    43321 cacattactt ggcttagtaa aaagcaaagc aatcgtcaga cgggtcgctt ctcccccact
    43381 taatgtacat aacggtttcg tcaaagtttc ctgagcaaac cctaagtgat tcagcaaact
    43441 acggacaagc gattctgaaa actctgtttg tctcatgaca aaacgaatga tggattcttc
    43501 agatgtcatt tgataaccct tttgctgata tacttgaaag cttactttcg gagagagaag
    43561 gattccttct ccttgtttgc ggatatgttc taataaggtt gtcttacctg aaccattttc
    43621 accgacaatc gcgatttttt tacctaaaga aaactgaaaa tcaccattta ccagtaatgt
    43681 tctcccactt ctttccaatt ggacattttg tcccatgatg ggatagcggc tgtggagttc
    43741 aagagatttt ggtactggaa aacggatttg tttcatctgc tgcggcttgg ttgtttctcc
    43801 tattttttgg agtcttctct ctaatgtttt cgcattcttt tggatggctt tttgtacact
    43861 gtctttttgt ttagaggaag acaaccgatc cggtctgatt tgttgctttt tctttttact
    43921 ggacactttt tccaactttt ccgcttgttt tttcttttct tggatcgatt tttccaatcg
    43981 ttttttctct ttcatgatcg actctgcttc tcgtagctga gtctttttct ccaattcctt
    44041 ttgagtgaga taggcactat aattccccga aaactctcgg atttctccgt cttttacttc
    44101 ccagattttc gatgctagct catctagaaa atagcgatca tgactaacaa aaaccagcgt
    44161 accataataa taacgaagct cttcaatcag tcgatcaata ctttttctat ctagatgggt
    44221 tgttggctcg tctagaagca tcccttgttc ataagaagaa agaagacgta tcaactcgat
    44281 ctttcgttct tcccctccgc tccatttccg ctctgaagtt tcttccagtc ttaactggaa
    44341 atgactggct aattccaaat ttaggtcctt tgcttcagcg agataggtta attgaggcag
    44401 gtagttgaag gtgatctctg tttggatttt cccatgatcg ggaaaaagtt caccggctat
    44461 tagtttgagc aaagtcgatt taccgacacc attttctcct atgatcccta tacgatcttg
    44521 ctgatagaca cgaagagaat caatagatag ttctagctgg ttgccaaagc tgacttgtag
    44581 atttgttata tttactgcta aattttccat atgttttaca ctcctatttc atgtaaaaca
    44641 acaattatcg atactaaaaa agagcagaaa aatctgtttg caaaaaaact gcatcacatc
    44701 ttttcctact ctgaacgaaa taactatgac taaatcacca aatctgtcat agctttcacc
    44761 tattctactg tcgttcgaaa aaatggacat actccatcca tgaaattgtt gtttatacat
    44821 gtcttttgaa tttatttagt tgttattcaa aagttcgaaa cgtaatttca tcgatgcagt
    44881 catttttccg acctcctttt ttattaggtt accacacacg attcaaaaaa agcaatagct
    44941 actgaatagt aactgaaaac cttttattcg aacgtagtga tcttttctgg tgctaaacga
    45001 acagactcgt aaccttcttc taccgctttt cctattgata aaataataac tggaacataa
    45061 cggtctttat ccaaaccaaa tgcctctgcc aactgatctg cttcgaatcc accaattgga
    45121 tttgtttcat agccatgatc acgcgcaact aacatgaatt gcatagccgc taagctagaa
    45181 tcgactttga ctacatcgtt catttcttct cttgaaaaac tcttgtaata aggaatgatc
    45241 gcagctaatt gttgatctct gacttctttt ggcatcttcc ctgattcgta agcttggtta
    45301 tagatttctt cgccatattc gtaacattgc atatcgccaa aaatcatgac cattgcagaa
    45361 gaagtatcat tttgtctcgt attgaaacgg atcaaaggac gcaagatttc ttttgcttcc
    45421 tcgctttcag cgaccacaaa gcgccatggt tgcatattga cagaagaagg tgcagtcgtc
    45481 gcttctttga tcatttccag catttcttcg tgtgggattt tgtatgtttc atcatatacg
    45541 cgaacggatc ttctaccagt cataattgtt gaaaaatcat ttttttgttc cattattatt
    45601 aacctctttc gtttctgttg ttatattgca aagttgggta ttcaatttat ctaaaagtgt
    45661 tagaaattgt ttcatttcta catcgctgaa agccggggat agcacggaac ctgtatcttt
    45721 atggtccatt tcacaatgct cgattttctt ctgggctttt tctgttagcg ctacatacac
    45781 ttcccggttg ttctgaggat ttctctgacg cgaaacatag ccatttgctt ccaatacctt
    45841 cagatgacga gtaactgctc cttgatcaat ctgcaacttt tcttgcaaac tgctttgtag
    45901 caatggattt tcttctttca gtctcatcat gatctcgtat ctagtaagac ttataccgat
    45961 attttcttca aagatctgga cgattttttg atcggctaat ttgatttgat ataaaaggtg
    46021 actaatctct tctaaagaca taatttcctc ctttctaata attgactcgt caacgattga
    46081 cttgtcaata atagaataaa aaaagaaaaa agtcaaagaa tcagctgtgt aataaaaaaa
    46141 acgctctcaa tagaaaagta tagagaaaag aaattttttg tagaatgaac ggaaaaaatg
    46201 ataaagaaag cacaacgcta aaaccaagat tattgattct tatcaaacta tagaagatag
    46261 ctcttctgca gtagaaaatt ttacaccgcc aaaaatttcc gaaatcgcct tttgcaagaa
    46321 tcccgtcgaa tattagaaat tggatcagta tgcttaaaca gtaataaaaa agttatgaca
    46381 agatgttgtc acaacctttt ttgagtaaac ggtgttcaaa aacttgcatc tgcggtaata
    46441 agttcaacca aacaaaaaac atgaaaatct gtttttgttt ggctgttctt actacttgat
    46501 gcagggcagc tttttcacta cctcttttta ataaccataa aatcctattc cttcatatct
    46561 ccagcccatc ggtgttagcc aatctctttc cttagcactc aaggtatagt gatgggtacc
    46621 agttttttca tttggattaa atagtcgata aattggcttg gaaccaccag aataaaaact
    46681 tagaccttca taacgccaac cgatttttgt taaagagttg atctcagatt gtgccattgt
    46741 gtaatgatgg tctccactgt aaggattgta taaacggtag acaggttgtc cgctgtttgg
    46801 tgcttgccaa gcaatccctt catattccca gcctacagtt ggcagataat ttttttctcc
    46861 ggcattcaat gtatataaat gttctcctgt atgacggtta tacagacgat acatcggaga
    46921 agttgaagtt ggtgctgtat catactgtgt cagattatag gtttcgatta cattgttcaa
    46981 tgtagaacca taattaggcg cagtggcata acgacctgtt agccaagccg tagcatcttt
    47041 gtaagagttc gtattgcttt tccatgcacc ggaatagtag taaacgcctg gctgaaaaga
    47101 agtcgtcttc aataccgtta cgttatcttg caatgattct ttgtacgaag gatattttct
    47161 aaaagcggca ttcaccgtaa tccattgccc attcacatat tccgaagtag gcatcgtaac
    47221 agattggcca ttatagcttc ctttaatccc aaatagattg taattagggg cagaagccaa
    47281 agtactgttc ccccagccac tttcaacgat ggcttgagca atcatgactg atgcatataa
    47341 gtcattggca cttgccaaac tttgtgcagt tgaggcaata ctatcaatga acgcttgttg
    47401 agaattagca gatgagcgag cataaaaagc atagccagta tagttttcga attcagacaa
    47461 atctgcttga tgggtatgtg tcaatgtttg cccatctgtc aattggttcg tgatttcttc
    47521 tgcattctct ggattgttct gagcttctgc tgatgtactg tcttcggttt gtgtttgttc
    47581 tgttgtttca gttgttggtt cttcggttga aattgtattt tctgagacag tagctgactg
    47641 caaagtactc tctgtatcgt tttcaattcc tgtttctgaa gaactcgatg tctgagttgc
    47701 gacagtttct gtcgattctt cagctagcac tgttgtgttg gcaactgcta gatttcctaa
    47761 aagaataacg ctaaataata aattctttgc tttcatcttt tttctccttt gaattatgaa
    47821 acttttccta aataacagtg taactaaaaa agtaaaagca agtcaatgtc catatttaaa
    47881 taacatttgt ttctttttga taaatttgct ttttctacat aaaaagacgt aaatgaagaa
    47941 tattcttctc cattcacgcc ttaaattgat ggtcgtttga ataactattt aacaagtaat
    48001 tctctttgga tattatccgt tatggattat acttcctgtg tcgtcggacg gataatcatg
    48061 ttactgacag acatccggtc tggcgtttct atcgcaaatg ctacagcaga agctatatct
    48121 tcggaggtca atccccattc tttttgcgct tcatgaagtt caagagcagc ctttttgtcg
    48181 ctgatggttt gatataattc agtttgaaca gctcctggag agatgatcgt agatttgatg
    48241 ttattttgcc gttgctcttg acgtaatcct tccatgattg cacggacagc aaattttgtt
    48301 ccgcaataaa cggcggaatc aggataaaca acatgtcccg ccacagaatc agttgaaatg
    48361 atatgcccag atttttgttt ttccatgatt ggaagtacgg cggaaattcc atttaacaca
    48421 cccatgatgt tgatatcaag catattttgc cattcatcac ggtgaccttc aactaatgga
    48481 gcggttggca tgattcctgc attattgtac aatacatcga ttcgaccgaa cttttccatc
    48541 gctaaatcga taactgcttg gacttgtgca aaatctctta catctgctgt ttgaatatat
    48601 agctcagctt ctggtaaaga ttcttttatt gcttttaggc gatcttctcg gcgtgcagct
    48661 ataactagtt tagccccttt ttctgctaat agcttcgttg ttgcttcacc gattccgctt
    48721 gaagcgccca tgatgacaat cactttttct gataaatcat tcattctatt ctcctcctgt
    48781 tttgaaaaat ctcttgctta tactcactat ctcttatttc atcttactgt tcaaataatc
    48841 cgttcgacag gtttgacgat tttggcaggg attcctgcaa cgatggtatt gtctgggaca
    48901 tctttcgtaa cagttgcatt cgctgcaaca atggcattct cgccaatcgt tacgcctggc
    48961 agaatagttg ctcctgctcc gatccaagca tttttcttga tgtggattgg ctttactgac
    49021 aagcctcttc gttcttttgg atcggttaga tggttcaccg tgatgaggtt gacacgagga
    49081 ccaatcaata ctgaatcttc taaacagatg ccacctaagt caacgaacat cacttgacga
    49141 ttgataaaga catttttccc tatactaata tgtttgccga aatctgtata aaaaggcagc
    49201 agaacagtca ccgtatcatc tactttgtca ctaatgatat tttctagccg tttgcggata
    49261 tctgctggtt catggtaccc agtattcagc gctgctaaag gctcttcgtt ttcagcttgg
    49321 atctgatgga tcacttcaaa gagcggatcc gttactcgaa tctctttatt gacgatttgt
    49381 ttttcgatga ggcttgtcat tttgctccct ccttttatcc ttactttata acggacggct
    49441 tatcatgtct aatacttata aaacatactt aactattcct tttaactata cttagtggta
    49501 tgctttttta aaaacaggag ggaaaaaatg gatattcgta tactgacgta ttttttagca
    49561 gtagctagag aaaaaaatat cagccgagca gcaaaatctc tgcatatcac gcaacctact
    49621 ctctcaaaac aactgaaaga tttagaagaa gaacttggtg tgacactttt cactcggggc
    49681 tcccgagaga tacagttgac ggattctggt cgatatcttt attcaaaagg aaaagaaatc
    49741 ttgtcgttgg tagaaaaaac ggcgaacaat ttaacaaatg acgcaatcat ctctggagaa
    49801 atctacattg gcggaggcga aactaaagca atctctttca tttctgatag ccttcattcg
    49861 ttgatcaagg cgcatcctga tatccagttt catttatata gcgggaatgc agatgatatc
    49921 atagacaaac tggatagcgg attacttgat tttggactcg taatcgaacc gacaaacaaa
    49981 caaaaatacc agtcatttcg actgccagcc caagatcgtt ggggactttt gatacatcga
    50041 aatcatcctt tagcaaagca aaccgtcatc catccgcagg aactgaaaac tgttcctttg
    50101 atcatttccc ggcaaacgtc agtggacagt caactagctg aatggctagg tttcagcata
    50161 gatcagttat cgatcgtcgg aacatataac ttattgtaca atgcttcttt gatggtcgat
    50221 aacgggactt ttggtgcatt agctctagat gggatcatca atacttatgg gacggaaaaa
    50281 atattcatcc cactcgatcc gccattacaa gcttcactga atctcatttg gaaaaaagac
    50341 cagcctcttt ctcctgctgc tcgtaaattt ttagatgtcc taacggagaa atacagttaa
    50401 gtagagtttt tttccttcgc tttcagcttt ttaacaacga ataagataag caaaagatcc
    50461 aacgattaaa taacataagt ttcttaattt atttcttcct tttatttctg ataattccag
    50521 taaattacta taattataaa aaaagaattg acaaaacata actgtctata taaaattgat
    50581 tacgttaaca ataattcgtt tcatgtgact agatcatact aggcatgaaa aatctctgag
    50641 gaacatggtt tccctaggag gtttttcgtg tctatttttg tttggccgca atcaactggt
    50701 ctagcaaacg tgaaaaccaa atcttcaaaa agggtgcgcg catgaaaatc aaaaagatct
    50761 ttaatcaaaa tgcagtattg gtagatgacg gtggacagga aaaagtagct attggaaaag
    50821 ggattggatt tgacagaaaa agaaatgatt tgatttttga tcgtgatgtc gaacggatat
    50881 ttgtcatgga accagaaggt caaatcaagt tgcaaaattt acttaatcag attgatgaac
    50941 gctttttatt tgcagcagaa acgatcattg atcatgcgga aactgttttg atggaaaagt
    51001 tgaatgaaca tgtattgatc gctttgaccg accacattgc tttttctgcg gagaacatta
    51061 ataacggtat cgtcatccgc aacaaacttt taagagaaat cgaagtgctt tacagtgatg
    51121 aattcagtat tgctcaatgg gcagtagagt atctgacaaa agagcttggg attccatata
    51181 cttatgacga agcaggatat atcgcaatcc atattcacag cggacgaagc ggtcggaaca
    51241 ataaccatcg cagtatccgt gaagtgacga ttgtatctga catcatccat ttagtggaat
    51301 cagaattgga aacagatatc cattcagaac cattttcact gaattattca agactggtga
    51361 atcatttacg actgcttcta caacgaaccc atgcgcaaca atatgctgtt ttagacacgg
    51421 aaatcgtaga aatggtcaaa cgaaaatacc cagaaagcta taagatttct aaaaaaatcc
    51481 gtgtgttgct gaccaaagaa taccagctcg cgatcacgaa agaagaactg ggttacttgg
    51541 ccatccatat cgagcgttta agaagcgcaa tcgtacaaac aaatgttaac aatcatgagg
    51601 aggaaaaaaa ttgaaagcat atctacaacg aatgggacgt tcccttcaac ttccagttgc
    51661 ggtcttacct gctgctgctt tactagtagg gatcggaaac tggtgggcat cttatagtaa
    51721 cgacattgtc gctcattttt tacaagctgg cggtaacgca gttttaggtc aattaccttt
    51781 gctgtttgcc gttgggttag cactagggat gtcagtggac aaatcaggtg ctgctgcctt
    51841 ggcaggtttg gtcgcatttg aagttccagt aaatgtttta aaaactgatt cagtagctac
    51901 tttattgaat atcaaaccag aatcagttga tccatctttt gctcagatca gtaacgtatt
    51961 tattggtatt attgccggat tgattgcggc agctctttat aatcgtttcc acgaagcaaa
    52021 attaccgatg gctttatctt tctttagcgg caagcgtcta gtgccaatct tggctgcctt
    52081 tgtcatgttg ctgatcagtg cagtgctact gctcgtatgg cctccggttt actctgcttt
    52141 agtttctttt gctaaattca ttttgagttt aggctggggt ggtgcaggtc tttatggctt
    52201 cttcaaccgt ttactgatcc ctacaggatt gcatcaagca atgaactccg tgttctggtt
    52261 tgacgtagca ggaatcaatg atattggtaa atttttggct tctgaaggaa caaaaggcgt
    52321 aacaggaatg tatcaagctg gatttttccc aatcatgatg ttcgggcttc cagcaggagc
    52381 atatgctatt tacagaaatg cacgtccaga aaacaaagca aaaacagctt ccttgatgct
    52441 agcagcagct tttgcttcat tctttactgg tgtgacagaa ccacttgaat tttcatttat
    52501 gttcgttgct tggccattat atgtcttgca tgcaattttc actgggattt ctttagcagt
    52561 gagtgcattc ttccattgga cagcaggatt tgcctttagt gccggatttg tcgattactt
    52621 cctatctttg aaaaatccga ttgcgaatca gccattgatg ttgatcgtcc aaggattagt
    52681 aacagcagtg atttactact ttggctttaa ctttgctatc aaaaaattcc atctgatgac
    52741 tcctggccgc gaggaagcag atctttcaga tgacgatact gcaacgacta attcagacaa
    52801 taaatatgcg gcacaagcaa gcaaaatcta cgctgcatta ggcggagccg acaatgtaac
    52861 ttcgatcgat aactgtacta cacgccttcg tttgcaagtc aaagatacag gcctgatcga
    52921 tcaaaataaa atcaaagcca ctggcgtacc tggtatgaag atcatcgacg gaaaaaatgc
    52981 gcaagtcatc gtaggtacag aagtacaatt cgttgcagat gagatggcaa aactacatgg
    53041 tggtgctgca gcacgacctg cacaaacaaa caccgtggtt aaaacagaaa catttgccgg
    53101 tgaaacgatc gaacaagata tttacgctat cgcaaatggg aaactgattc caatcactga
    53161 agtttcagat gatgtattcg cggaaaaaat gatgggtgac ggctatgctg tattaccaga
    53221 aaatggagaa atcttctctc caatcgctgg tacgatcaca aacattttcc caacgaaaca
    53281 tgctgtcgga atccaaacag atgctggtat cgaagtcttg cttcatatgg gcatcaacac
    53341 tgttgactta aaaggcgaac cattcacttt atatgtagaa gaaggtcaaa aagtcgcaag
    53401 aggtcaattg attgctttag ttgatcttgc cgctattcaa tctgcaggca aaaacacgga
    53461 tatggtcgtt gtattcacaa atggcgacaa agtccaaagc ttagaaatcg aacccgcacg
    53521 tgatgtaaaa gcaaatgata aaatcggctc tgtttccaac aaagcctgag ccatcgtctt
    53581 ccccagactt ttttatcgat aaacaaacag gagctgagac aaaaatcttg tctcagctcc
    53641 tttttccgaa taaaaacggc gttctcctgc caactccgcg gtaataagtc cagctaaacg
    53701 aaacatatga agagctattt tttatttgac tcttcttatt acttgatgca gaacagcttt
    53761 ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct ctttatacat
    53821 tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg ttttcccaat
    53881 actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc atgttggatc
    53941 gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt ttcgacaaac
    54001 gctgcatcac ttgcttcaat aatttctaac tctttacctg tcgcacgctc taatgccttg
    54061 gctaattctt catagtcagt tagattgccg gataattcta agatttctgg agagtcactt
    54121 tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca acctgttttt
    54181 ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat gataggtaat
    54241 tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga atccttaatc
    54301 attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc ggcatctgca
    54361 aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac tacattctta
    54421 tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc tattcctttc
    54481 aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt aaatccagct
    54541 tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc attttgtgga
    54601 accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc tcctgttact
    54661 aaataatgca tatttgccac tccctattct ttttatttgt taagatttac agctgtacat
    54721 ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa aaaaaatgaa
    54781 aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg tacttgccta
    54841 tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca gtagtatcga
    54901 aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg gtttgatctt
    54961 tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga tttctttact
    55021 agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc caaaaacaaa
    55081 tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct acgctcggct
    55141 gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga tacataaaat
    55201 agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga gatttttata
    55261 attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat tcttttattc
    55321 tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag gtcaaagcgc
    55381 tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca ttagttctga
    55441 aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca ggtcaaagcg
    55501 ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca gatttctccc
    55561 atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc aacataggcg
    55621 taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc atttcttaat
    55681 tcttcaggcg attctgctaa agcgcttaca acaagatacg ttccttttgg gaatgggatg
    55741 attcgcgtag tgtttggaac atcctgactc gtttgaacac cgacatagta catcattttc
    55801 ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg tttcaatgca
    55861 tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc agccaaaccg
    55921 acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt aaaatctggt
    55981 ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt aagttcatct
    56041 tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat atttttattt
    56101 tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt actgaaatcc
    56161 tctccccatt ttgtaaaaga gatctcggga gcttcgacta acccataatc tgaagaagga
    56221 agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa tggcccttta
    56281 ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc agcgtacgga
    56341 ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc ttccaagcgg
    56401 tctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc tcctaactta
    56461 tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat ttcttgattg
    56521 actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa ctgttctttc
    56581 ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa tgtcaagcgt
    56641 ggaaaagatt tttgtatgcc gtatctactg atttctgaag gcagatatcc tgaccaatca
    56701 cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc cgtttctgtc
    56761 actcttgatc catctagaag atcgcgatta gccaaagcca atctacggtt tttgatatag
    56821 tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata ttcagagatt
    56881 cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc ttcgatgtaa
    56941 tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgattg cctttttatc
    57001 atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc agatgtagaa
    57061 aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat aattggtatt
    57121 atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca gattctaagt
    57181 aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta cctactgtac
    57241 aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc tttgcgatac
    57301 atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca cttcattttt
    57361 gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc ttttactttt
    57421 tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga gcaaaagtga
    57481 ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac taaatataaa
    57541 taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt cctgaaaacg
    57601 ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg aactatacaa
    57661 gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg atcacttggg
    57721 atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa aaatgcaaac
    57781 acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc aactactcac
    57841 tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg gagcttttaa
    57901 cagagattct tatagaacat ccgcacttta tcgaacgctt caaagttaag atgccatttc
    57961 atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat catattatca
    58021 agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag ttcatccaag
    58081 aagcagttga atcgcttatt cagcaaaatg cctatcttcc cgcattcgaa ttgatcaatg
    58141 aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga acccttcttc
    58201 tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct catgcagaaa
    58261 aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc tcttattcaa
    58321 aacgctactc tataaaaatc ctgaaagaag actttcggga aaaagaattt tctaaccaaa
    58381 agaaaaaaat agataaaaaa ctaaagaaac ggtaaagaaa gacgatttca atgaaaaata
    58441 gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc ttgctttaaa
    58501 aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa tattagtcat
    58561 ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc gttgctggat
    58621 agattttccg gcattgttga tagattttat gatacttttc tacattttgt aagagaggtt
    58681 ccgctgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg tcgaaccacc
    58741 ctaaccctag tgcagcaatc attgttgcgc ctaatgcagg tccttcctcc atacttaaac
    58801 aatagaccgt tgcatcgaaa atatcagctt ggatttgtag ccatgcaaga tttttcgcgc
    58861 ctcctcccac cgaaacaata cgtgtaaatc tgcgacccgc tagttcttta cgtttcaatc
    58921 ccaccattga caaatgctca ttaaaaattt agaatattca caagtttaac gacaattatg
    58981 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
    59041 cgatcaaaga cacgttacct accgttttcg gttatatcgg tattggactt gcatttggta
    59101 tcgttgggaa agctgccgga tttcatccac tagtcgtcac gttgatgtcc ctgctggtct
    59161 atgctggttc tgcccaattt atcacagtca gcatgcttgc tagtcacagc ccattgcttt
    59221 ccatcgtttt ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
    59281 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
    59341 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
    59401 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
    59461 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
    59521 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
    59581 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
    59641 tcccaagcaa cttagtgatt gtagttgtaa cactgattgg gtgcggattg ggggtgtgga
    59701 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
    59761 tggctttcta gggtcctacc atttgtctta ctgaaaaaat tcgatttacc gcaaccgttg
    59821 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
    59881 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
    59941 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggcaggaatt
    60001 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
    60061 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
    60121 atccgttgaa cggaccacta acaacgactt ttcctaacat atgtcctgtt tctacgtctt
    60181 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
    60241 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
    60301 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
    60361 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
    60421 caaatggtcg gacaaggtgc ttgatttgat caaagtagcg ggtaatatcg aataatacag
    60481 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
    60541 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
    60601 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
    60661 cggatccgtt gatcactaag atttttttcc cgcgattggc attttcttct ggagttagac
    60721 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcagctt
    60781 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaact agttggtatt
    60841 cttgattgct tcctgctctt gttgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
    60901 atttttgcac ttcgtcacct acagcaacaa ctttcccgac tccatcaaaa cctaagatac
    60961 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
    61021 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
    61081 caataaagct ttttggatca tcgatcggca acccttcata aaaaccgact accttcatta
    61141 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
    61201 gttcatttca atatatatag tatgctattt gttccacctt ttttattcat cataattatt
    61261 ctcttactta aagtaaacta tttgcacttt tttggttaaa aaagaggttg cgacaagact
    61321 tttgtcacaa cctcttataa acggtgttct cctaccaact cttcggtcac aagtcaaaat
    61381 attcatcaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttaaacgg
    61441 caggctcaca acctctgata taaacggtgt tcaatcaact gaccctcggt attagctcaa
    61501 aaaacgacaa aatatgaaga gctatttttg tttggctgtt cttattactt gatacaggac
    61561 agctttttca cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag
    61621 cgttggatgt tctttttcaa aggtctctaa gatctctcgt acttcatcag tagatttcgt
    61681 attcatcaac tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa
    61741 gaaacgatgt agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc
    61801 tagttgcaga cgaagtagtc cgatcagttc tttttctgta tgttccctcg ggtctttttc
    61861 aaatgcataa ggattcttga aaatccctcg gccaatcatg atgccatcaa cgccatattt
    61921 ctcggccaat tcttctcctg tctggcgatc ggggatatct ccattgatcg tgattagtgt
    61981 ttgtggagcg atttggtcac gtaaagcaat gattttagga atgacttccc aatgtgcatc
    62041 tactttactc atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg
    62101 aagtaggtga ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt
    62161 gacgctgaca ggcaaaccgc cagctttagc tgcttcaatc aattgtgccg ctacttctgg
    62221 acgaaggatc aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat
    62281 gttgatatcg attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa
    62341 ttctggcttg tctccccaaa tatgggcaac catcggctgt tcatcttctg taaatgttaa
    62401 tcttcctcgt acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc
    62461 agtaaagaag acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt
    62521 tacatcttcc attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt
    62581 agtcatttat ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa
    62641 cattgtcatt atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc
    62701 tgattgagca aaaaaaagac tgtgacaaaa atcttatcac agtccatttt ccggaataaa
    62761 tggtgttcaa aagcttgcat ttgcggtaat aagtccaacc aaacgaaaaa taggaggagc
    62821 tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca acctctccac
    62881 taaacggtgt tcaatcagct gaccctcggt attcgctcaa aaaacaacaa aatatgagga
    62941 actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt
    63001 tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg tacaaaacaa
    63061 cgatgaataa cacaagtacg atcatcgatg ttgctactgg cacatcgatc gttccaagga
    63121 atccgtaacg gaaaccggag atcatataaa cgatcggatt gacttttgaa acagcttgcc
    63181 aaaagggcgg taacatagag atggcataga aaacgccacc tagataagtt aacggctgca
    63241 agacaaatgt aggcacgatc gatacatcat cataagactg agcaaaaatc ccgttgagca
    63301 gtcctgctaa tgaaaacaag attgccgtca tcaataatgt aatgatgacc atgaaccatg
    63361 aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag ccgacgagaa
    63421 tactgcgacc cacaccacca atcacaaagc cccaaataat cacatgcgta ggaacaggtg
    63481 ctaccaagat ttcttcgata tttttctgaa atttttgaga gaagaaggac gaagaaacat
    63541 tggcatacga actagtgata gcagacatca taatcaaacc aggaacgatg aattccatat
    63601 atgaaaaacc acccatgtca ccgatccgcc caccgatcat ttttccgaaa ataacaaaat
    63661 acaaggatgt cgtgatcact ggcggaacca gtgtttggac ccatatacgc aaatagcggt
    63721 tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac atttttctcc
    63781 tccgtatgat tattttcttc tgtgattttc aagaacagtt cttctaaacg attcgactta
    63841 ttcctcatag aaagaacttt gattccttgt cttgtaagct gatcgaagat tccgttcacc
    63901 ccttgatttc gttcaacttc gacagcgatt gtctgctcat cttcaaatgt acaagcatat
    63961 ccttcaatca caggtttggt atcatatggc gctaaatcaa agataaatgt ttcaaattgc
    64021 agttttgaca gaagctcttt catacttgta ttctcgatca gttcacccga ttggatgatt
    64081 ccgatgttgc gacaaagcat ttcagcttct tctagataat gcgtcgtcaa aatgatcgtt
    64141 gtaccatttt cgttcaattc tcgtagaaac tcccacatct cgcgtctcaa ctcgatgtca
    64201 actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa tgccctagca
    64261 atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt tctcttttcc
    64321 caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt gcgagagaca
    64381 ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaagg gttaaaattg
    64441 aactcttgtg gaaccaatcc aatctgttgc tttgctcgaa ctagatcctt gtccagatca
    64501 taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat aatcccgatc
    64561 gttgtagact tcccagctcc atttggccct aatagcgcat agaaatctcc ttctttcacc
    64621 gaaagatcga ttccccgcaa tgcttcgacc ccacttccat agatcttttt caaattattt
    64681 atttcaagcg catttgccat ttatttccta tctccttata gacatgattc ttaattgtat
    64741 catggaatac agcagatgaa aaaacaactt ggcttccaca caaaaacaca cctgctaaca
    64801 aagaggagat gtgttttcta gttcatgatc atcttcgata gaataactat ctaaacaact
    64861 ctggaacttt taaaatcata aaagtaccga cagcaactac tacgatgaca tatagaagat
    64921 ccttataact gaggttcttg tcttttttat tcatgttaag ctttcctccg tccttttatc
    64981 gaaagctttt ttcttttatt ttaaccgaaa taaataaaat ggaaatagtt attttcaatt
    65041 tctgttttcg ctgtttgttt tacggagaac tttgccatgg aacgtgcgtc tcgtcgctga
    65101 tgctaagttt tttcgataaa agctgctaga aggaagacag cgtggtttat tttgtatcgt
    65161 cttttgctaa atcttccaag atcatctgga cagcagactc gttcccattg aattctgcca
    65221 cttttttggc atcaatgtac ttcttttgat aatcgtcttt ttggacccac gcatcatgct
    65281 tcgtttgata aagttaatca aacggatacc actgacgctg ttcatcgaac aacaaacttt
    65341 ctttttgggc ctgttcaact atggatttag gataattcaa aactttcagc aaggcaatcg
    65401 catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt ccttttcctt
    65461 ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc tctgtcaatt
    65521 cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac cgaacgactg
    65581 aagcggaaga agcaatccgt tcgatcgtat ttgttccttt taaaatctca tctacgaagc
    65641 agtagcagcg ttctttggaa gccacttggt ccagcaaacg tttgatcgat ttgatttctg
    65701 aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa gtcaacacat
    65761 gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt gctagaatac
    65821 agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa cccgtgacta
    65881 atgtattctt ctgccagttg actggattaa ctaccgcttc ttttaacaat ggatgataga
    65941 tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatc ggcatatagg
    66001 tgcgataatt caaaacggct gctgcaactt ccaattctcc cagcaattcc cacagcttga
    66061 tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag ataaatggca
    66121 gcatgaacat gatgttgaca tattcaaaaa tcaattctgc ttcactcccg ctcttcattc
    66181 gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt ttcagctctt
    66241 tttgaagtgg tgtcgtcatt tttgctaact gattggcggc tgaaatcgtt gaaaccaaat
    66301 aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa tagaccgtat
    66361 tgaatactaa gccaccgatt gctagataga ttcctagtac ttgccctaaa agaagcaaac
    66421 ctacacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt ccaatctttt
    66481 tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt cctaaacgag
    66541 cgaattgata ttggattctt tctctcagtt gaggattttc ctgataaaaa gcaattagtt
    66601 tttctaactg ataatcttct ccaaaatcaa agctacgtaa acgctgatac aacgcttctg
    66661 aacctacact agaataggta ctgttgatcc cttcaaatac ttcgaacata tccaagtcat
    66721 accaagtaag atcgtcgatt tcactatccc atgaacggaa ttttttctcc gtgagccacg
    66781 catccttcaa actttcttct ttatcaaatc tcggttgata aggaattttt ccccaattac
    66841 tacgaactgt ttcctttact ttcaaacgtg aaaaaatgtc taaaacaact aataaaataa
    66901 caactgcaat aataattaaa acgataaatt ctctttggcc catatccctc tccgttcctt
    66961 gatttgttag ttttagtata gcactgttgc gctatttgaa aagggggtac aaaaataact
    67021 gtcttcgtta cctaattcgt atcaatcaca ccaaaataaa aacaccttcc aaaaaagaag
    67081 atgtctttaa aacgagatac aattttttgt cattcacttc aggtaaatta gagccaatta
    67141 aaccctccgc aacttgacgg agatggagaa gatgcccccg tctaatctag cggtcatctc
    67201 tcctcccatt ccttccacca atttttttga caggtaaagc ccgattccgc tagattccgt
    67261 atttgtgcgg ctggtatttt cggtataaaa acgctggaag actttttcaa cagaggtttg
    67321 cgctcctggt ttgataggat tggccactgt taatcgaatg aatgaatcct cttttgaaaa
    67381 tgtcaccttt gcttgtccat ctgcataacg caataaattc tgtatgatat tttgcagcac
    67441 tcgcagcaac atgagcggat ctgctaatac agttgtattt atcgagtgtt cagcgaacgc
    67501 tacctcgata tttttctcag aaaattgttc ataaaaagag aaaaatactt cttccacctc
    67561 tttagaaaaa gaaagcgtat ggagatccat ttctttttgc ttcgtctcta ttcgagcaag
    67621 atcataaaac tgatccgtca tactgagtaa tcttgcaaca gattgtttga tgatcgttaa
    67681 atacttctcc cgtttctccg tatcctctac ctgttccagt aattgtacat aaccgttaat
    67741 agcagtcaaa ggagttctga gatcatgaga aaggccgacg atcgatagtc tgatgttttc
    67801 ttccatttct tgaaatgctt gtcctttttg ttcattttca tccacccatg tattcagtgc
    67861 atctactagg tccattagat tcttttctcg aaattcgact gaaagacgac caccatattc
    67921 ttgtcgttca gaaagagtgg cgattttctt agttaatctc ttgatttccc tttgcaggaa
    67981 gaaaataaaa cttcccataa agataacaac gagaagcaac agccacttaa tcaaatctaa
    68041 accccactcc ccacaccgta tgaatataca cagcatgtgc ctttgctagt ttccctcgaa
    68101 gattggaaat atgcatattc actgttttct cactatcaaa atatggttct tgccaaactg
    68161 tttcataaag atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa agcttcagca
    68221 gatcgaattc tcttcctgtc aaatggacag ccacaccatt cacatttaca tccctcgact
    68281 ctttgtccag taagatttcc ttgtaataga tgcgttgcga cagatctttt acttggacag
    68341 aagtctgatg acgaagttgg atgccgattc gtaacaacag ttcttcgata tcaaatggtt
    68401 tcgtcacata gtcatccgct cctgctgcca acaaggaaac tttatctctt tgatcgcttt
    68461 ttgctgaaag aacgatgatc ggaacattcg atgtctgtcg gatttctgct aacaatgctt
    68521 cacctgaaag ccctggaagc atgagatcta gaaggatcaa atcgacagga tatgtgctta
    68581 acaataattt tccttccgta cctgaataag catcaagaag tttgtatctc tgttcaagaa
    68641 cctcctccag taaagaatga acagcttcat cgtcttcgat aatcaaaata gtttccagca
    68701 ggaacaccta cttaatgtca gatttttgga aaataaacat tcctagagct gatgatacca
    68761 cgattgttac tagactgacc agaatcattt tcggtgcttg cgaataagtt gcttgttgcg
    68821 caaagtccgt atacatgagc cacgtttccg taaaccactc cgttagaaat tccaagcctt
    68881 tgatttttgc gaaaacaccg ggaacgaagg ccgttcccat gatataaaga aaagaaagaa
    68941 gcaaactgac actggtactt ctagtgatga atgtcaaagc cactggaaca gataatgtcg
    69001 ctaatatcag cagaagcaat acaggaaata cttttagaac ataatttcca tagtttttga
    69061 ttccctcaac ttcaccaaat ccgaaagcaa gtgtgtaagc aatcatggct agccccgtaa
    69121 tcaaaaccac gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac acataataag
    69181 tcattcgatt ccgtcctaaa gataacgtat tgcgaatcgt accgttttga aattcttccc
    69241 caatataaaa gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc attttttcca
    69301 ccattaaaat ccctgttgca ccgttgatga ctgtatccgt tgcttggttt aattcattgc
    69361 cgtattttgt atgcatatac cattcgttcc aagaataaaa aagcggaagt acgaccatca
    69421 gtcctagtga gacccacatt ttacggctct tccatacttt tattttttca gcagttaata
    69481 gattaaacat gtggattgcc tccagttaat tgtaagaaat aatcttccag tttttgccca
    69541 actaggtgga taccatccac aggaactttt gcctctacca atgcttgatt gatggctgct
    69601 acttggtcaa ttccttcaaa aagctggata acacggctag attggacaaa ataatcccta
    69661 taaccaagag agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc aatttttata
    69721 aattgacgag attcttgtgc caattcttct ttcgataatt ctttgatcaa gtgtccttca
    69781 tgcaaaatac cgtagtgagt ggcgatctgt gacaattcat ctagcaagtg gctagaaagc
    69841 aagacggtga tgccccgttc ttttaccaaa cgttggatga tttctcgcat ttctgccatc
    69901 cctgctggat ccatcccatt cgtcggttca tccaaaatca aaaattctgg attcgtgatc
    69961 agtgcatttg caatagctaa acgctggcgc atacctaaag agaaattctt tgctttcttt
    70021 ttccctgtat tttccaatcg catcattttc agcaggtctt cgatttctct atccgacaca
    70081 ccgccgttcg ctgcttggat acgtaggtta tctcttgcag ttaattctgg ataaagagca
    70141 ggggtttcaa tcgattgacc catacgtcgt cttgctgcct gcaaatccgt cgttccaaat
    70201 aattcgatcg aaccttcatc aatcgagatc aaacccataa tagttctcat aaaggtagac
    70261 ttacccgctc cattctcccc aatcaaacca tagatcattc cacgtttgat ttcgatcgat
    70321 actttatcta atgctttggc agcaccgtat tttttggtta taccagttgc tttcaagacc
    70381 gtttcatttc caaaatccat acttatcctt ctttcttatt gataagtgaa gtatagttga
    70441 cgggtataaa gaaagcagcc agaaatgtat aaagaaagtg taaattttcc aattgaattt
    70501 caagaaaaat cagactgtct cgcagacgtg gttgagttgt ctgccaatca aagagcgcac
    70561 caaacagtgc taatccaagt ggactggcca ccatggtaat cgttgttatc gttgacatca
    70621 gacgtccttg tatatgcgtt ggaacttctc gctgaagcca gaccatataa aaagcaaaag
    70681 aaaacattaa tccttaaaaa cggacttatg aaaaataata catgccgttt gggatttaca
    70741 attagctacc aaataagagg ttatgacaaa agacttttca caatcccttc ttccgaataa
    70801 acggtgttct cctgccaact cctcggtcac aagtcacaat atttatcaaa catgagaagc
    70861 aatttttgta aattccttct tatttcttga agctgaccac ttctgtcaca acctcagaag
    70921 cggataaata atattgtttg atgatacttt atctttttcc cgtttgttta tagatcgaat
    70981 gatattatag accaagaatc ctacctatta acatagctaa aaacacaaaa aaggcacttt
    71041 ccaaattgtg gaaagtgcca gaaaagttag gattaaggta actgcgctca gcattgcttc
    71101 gcccagtacg attctcgtaa ctcgtgaact cgaacgataa tcgcaattaa cgttttgaga
    71161 actgtgaagc tttacgggct ttcttaagac ctggttaaac aaaactctat tttattgcat
    71221 tttacaggaa tgtatttcat gcgaaattaa taagtctttg tttatagagt tttactaggg
    71281 tataaaaagt tgtatgttat cattacctca aaacattacc tcagcttggc gagttggttg
    71341 attgaagaat aaatcattta tctagatatc tcaataaaaa atgatttcta agaaacttgt
    71401 attttcgtgt tattattttt ttgccctatc aaaatttcta attcttctag cgtaatatga
    71461 ttatgacaca taatcgattc aattacttca atacctattt ttttcgagaa agatcccttt
    71521 tgttcactca caaaaatact ttcagaagac atatataagg aacgaagttt tggaattagt
    71581 atatcgtaca aatagaccac cataaaatcg tccttgcaac cattctcaaa aagaattaaa
    71641 tttgctgatt gtgttacata tatcactgaa ttacattcat ggtcaattcc aaaaacaatg
    71701 tctacttcat tttcttttct aattcgcgca gttacatttt tcaaactttc accattactt
    71761 ataaatgctt tagttactgt aagctctgat gtttgttcag atattccttt tataatattt
    71821 tgttcatcag ccacattccc cataaatccg ccgattcctt ttaagtaata attctcacct
    71881 aagagtcgct tgcattcact gaattgataa aaaaaccagt taaaaaaatc ttctggaaaa
    71941 ataaattctg atcgaacttt atttatattt ttagctccta ttaattttat aactcgatta
    72001 atgttcactt gctgcgatga acatataact gaataaattg agttgtttaa ttcaaaaaaa
    72061 caactttaac atatgcatca ttaattcgtt attttttagg tagatattga tcattgttat
    72121 ctctcttttt ttgcttccca tactccaact tagaaattgc cgttataaaa tttattttaa
    72181 aggtgacttt ttcccctgaa gtatcggtag taggaatact taatacctca gcttctgagg
    72241 aggtatccca attatagtta tactttgcat catcaccata aagaacaatt ccattttttt
    72301 tatcttgtgc cgttagcttt actggttcgc ttacttttct tgttaatatc ttggacttta
    72361 catcatcgat attgcttatt ttatcaagct taaataattt acaaattaat ttcgtactag
    72421 tttttatatt tga
//
LOCUS       DAIGQM010000004        68494 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.004, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000004 DAIGQM010000000
VERSION     DAIGQM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.004"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            5..304
                     /locus_tag="NOA48_000204"
     CDS             5..304
                     /locus_tag="NOA48_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0788507.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            377..1738
                     /locus_tag="NOA48_000205"
     CDS             377..1738
                     /locus_tag="NOA48_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0788508.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1760..2020
                     /locus_tag="NOA48_000206"
     CDS             1760..2020
                     /locus_tag="NOA48_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788509.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2034..2786
                     /locus_tag="NOA48_000207"
     CDS             2034..2786
                     /locus_tag="NOA48_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCI0788510.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2880..3485)
                     /locus_tag="NOA48_000208"
     CDS             complement(2880..3485)
                     /locus_tag="NOA48_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0788511.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3538..4512)
                     /locus_tag="NOA48_000209"
     CDS             complement(3538..4512)
                     /locus_tag="NOA48_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCI0788512.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEHFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4890..5609)
                     /locus_tag="NOA48_000210"
     CDS             complement(4890..5609)
                     /locus_tag="NOA48_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0788513.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOA48_000211"
     CDS             complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOA48_000211"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0788514.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7160..8557
                     /locus_tag="NOA48_000212"
     CDS             7160..8557
                     /locus_tag="NOA48_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0788515.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8638..9078
                     /locus_tag="NOA48_000213"
     CDS             8638..9078
                     /locus_tag="NOA48_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0788516.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9226..9552
                     /locus_tag="NOA48_000214"
     CDS             9226..9552
                     /locus_tag="NOA48_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0788517.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9553..10302
                     /locus_tag="NOA48_000215"
     CDS             9553..10302
                     /locus_tag="NOA48_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788518.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10382..10837)
                     /locus_tag="NOA48_000216"
     CDS             complement(10382..10837)
                     /locus_tag="NOA48_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0788519.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11264..11539)
                     /locus_tag="NOA48_000217"
     CDS             complement(11264..11539)
                     /locus_tag="NOA48_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788520.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11833..12648
                     /gene="thiD"
                     /locus_tag="NOA48_000218"
     CDS             11833..12648
                     /gene="thiD"
                     /locus_tag="NOA48_000218"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCI0788521.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOA48_000219"
     CDS             complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOA48_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI0788522.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14769..17435
                     /locus_tag="NOA48_000220"
     CDS             14769..17435
                     /locus_tag="NOA48_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0788523.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17799..18551
                     /locus_tag="NOA48_000221"
     CDS             17799..18551
                     /locus_tag="NOA48_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0788524.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18573..19727)
                     /locus_tag="NOA48_000222"
     CDS             complement(18573..19727)
                     /locus_tag="NOA48_000222"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCI0788525.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19912..22353
                     /locus_tag="NOA48_000223"
     CDS             19912..22353
                     /locus_tag="NOA48_000223"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCI0788526.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22683..23387)
                     /locus_tag="NOA48_000224"
     CDS             complement(22683..23387)
                     /locus_tag="NOA48_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788527.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23574..23819)
                     /locus_tag="NOA48_000225"
     CDS             complement(23574..23819)
                     /locus_tag="NOA48_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788528.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23836..24687)
                     /locus_tag="NOA48_000226"
     CDS             complement(23836..24687)
                     /locus_tag="NOA48_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0788529.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24853..25857
                     /locus_tag="NOA48_000227"
     CDS             24853..25857
                     /locus_tag="NOA48_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCI0788530.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26098..26454)
                     /locus_tag="NOA48_000228"
     CDS             complement(26098..26454)
                     /locus_tag="NOA48_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0788531.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26822..28009
                     /gene="tuf"
                     /locus_tag="NOA48_000229"
     CDS             26822..28009
                     /gene="tuf"
                     /locus_tag="NOA48_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0788532.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOA48_000230"
     CDS             complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOA48_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0788533.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30814..31575)
                     /locus_tag="NOA48_000231"
     CDS             complement(30814..31575)
                     /locus_tag="NOA48_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0788534.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31742..32374
                     /locus_tag="NOA48_000232"
     CDS             31742..32374
                     /locus_tag="NOA48_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI0788535.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32433..33293
                     /locus_tag="NOA48_000233"
     CDS             32433..33293
                     /locus_tag="NOA48_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCI0788536.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33478..35793
                     /locus_tag="NOA48_000234"
     CDS             33478..35793
                     /locus_tag="NOA48_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0788537.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35975..37816
                     /locus_tag="NOA48_000235"
     CDS             35975..37816
                     /locus_tag="NOA48_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCI0788538.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37840..38949
                     /gene="rpoD"
                     /locus_tag="NOA48_000236"
     CDS             37840..38949
                     /gene="rpoD"
                     /locus_tag="NOA48_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCI0788539.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39169..41268
                     /locus_tag="NOA48_000237"
     CDS             39169..41268
                     /locus_tag="NOA48_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0788540.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41464..42327
                     /locus_tag="NOA48_000238"
     CDS             41464..42327
                     /locus_tag="NOA48_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0788541.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42432..42905
                     /locus_tag="NOA48_000239"
     CDS             42432..42905
                     /locus_tag="NOA48_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0788542.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            43001..43888
                     /gene="xerD"
                     /locus_tag="NOA48_000240"
     CDS             43001..43888
                     /gene="xerD"
                     /locus_tag="NOA48_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCI0788543.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            43907..44278
                     /locus_tag="NOA48_000241"
     CDS             43907..44278
                     /locus_tag="NOA48_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0788544.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            44248..45045
                     /locus_tag="NOA48_000242"
     CDS             44248..45045
                     /locus_tag="NOA48_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCI0788545.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            45029..45598
                     /gene="scpB"
                     /locus_tag="NOA48_000243"
     CDS             45029..45598
                     /gene="scpB"
                     /locus_tag="NOA48_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCI0788546.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            45604..46320
                     /locus_tag="NOA48_000244"
     CDS             45604..46320
                     /locus_tag="NOA48_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0788547.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      46402..46527
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46650..47261
                     /locus_tag="NOA48_000245"
     CDS             46650..47261
                     /locus_tag="NOA48_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0788548.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            47639..49162
                     /locus_tag="NOA48_000246"
     CDS             47639..49162
                     /locus_tag="NOA48_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCI0788549.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            49399..50739
                     /locus_tag="NOA48_000247"
     CDS             49399..50739
                     /locus_tag="NOA48_000247"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCI0788550.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            50892..51629
                     /locus_tag="NOA48_000248"
     CDS             50892..51629
                     /locus_tag="NOA48_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCI0788551.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51794..52015)
                     /locus_tag="NOA48_000249"
     CDS             complement(51794..52015)
                     /locus_tag="NOA48_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCI0788552.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            52046..53077
                     /locus_tag="NOA48_000250"
     CDS             52046..53077
                     /locus_tag="NOA48_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788553.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            53064..54467
                     /locus_tag="NOA48_000251"
     CDS             53064..54467
                     /locus_tag="NOA48_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCI0788554.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            54533..55168
                     /locus_tag="NOA48_000252"
     CDS             54533..55168
                     /locus_tag="NOA48_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0788555.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            55217..55897
                     /locus_tag="NOA48_000253"
     CDS             55217..55897
                     /locus_tag="NOA48_000253"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCI0788556.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            56032..57261
                     /gene="rpsA"
                     /locus_tag="NOA48_000254"
     CDS             56032..57261
                     /gene="rpsA"
                     /locus_tag="NOA48_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCI0788557.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            57443..58753
                     /gene="der"
                     /locus_tag="NOA48_000255"
     CDS             57443..58753
                     /gene="der"
                     /locus_tag="NOA48_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCI0788558.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            58996..59271
                     /locus_tag="NOA48_000256"
     CDS             58996..59271
                     /locus_tag="NOA48_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCI0788559.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            59506..60552
                     /locus_tag="NOA48_000257"
     CDS             59506..60552
                     /locus_tag="NOA48_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788560.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            60554..61813
                     /locus_tag="NOA48_000258"
     CDS             60554..61813
                     /locus_tag="NOA48_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0788561.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            61819..62400
                     /locus_tag="NOA48_000259"
     CDS             61819..62400
                     /locus_tag="NOA48_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCI0788562.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(62482..63357)
                     /locus_tag="NOA48_000260"
     CDS             complement(62482..63357)
                     /locus_tag="NOA48_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0788563.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            63505..63837
                     /locus_tag="NOA48_000261"
     CDS             63505..63837
                     /locus_tag="NOA48_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0788564.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            63949..65157
                     /locus_tag="NOA48_000262"
     CDS             63949..65157
                     /locus_tag="NOA48_000262"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCI0788565.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            65311..65766
                     /locus_tag="NOA48_000263"
     CDS             65311..65766
                     /locus_tag="NOA48_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788566.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            66128..66403
                     /locus_tag="NOA48_000264"
     CDS             66128..66403
                     /locus_tag="NOA48_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788567.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            66416..68494
                     /locus_tag="NOA48_000265"
     CDS             66416..68494
                     /locus_tag="NOA48_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI0788568.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
BASE COUNT        22620 a        11818 c        14353 g        19703 t
ORIGIN      
        1 aaaaatgaaa aatcggttaa ttgtcgcatg tggaagtgga gtagcaacga gtcagacaat
       61 cgctagtaag atccaaagta tgttagaaga tgacggcatc gcatttcctg tagaagcagt
      121 tgattacaaa tcgattcaaa atgagcttct aactgctgga atctatgtgt atgtcgcaca
      181 acctgatgag gaagtacttg aacaagcaaa agatttgggt attgaagtat ttccaggaat
      241 tccattttta actggaatgg gtgtagaacc tatttatgac agtatcaaag agttagtaca
      301 gtaaaggagg attgttggat aaaaaagttg gttcatagtt ttatttacta tatttagaaa
      361 gaaagaaggt ttatttatgg aagttttcca aaccattatc aattatgttt tgaacttagg
      421 atcagccatt tttgttcccc tgattatttt gatacttgga ttgttggcag ggatgaaatt
      481 aaaaaaagca ttcatgtctg ctttgacttt agggattgct tttagcggaa tgtctatggt
      541 cattggctat atgtctaacg cagtaagtcc agcatcagaa gcattggcta aaaatacggg
      601 aatcagtttg cctgcacttg atcttgggtg gacaggtgca gcaagcatca catggtcgtg
      661 gagttatgct tttatatttt ttgcagtaac gattggggtc aattttgtac tgttactttt
      721 taattggacg aagacgttaa atgttgatat gtggaatgtt tgggggaaag ctttaactgc
      781 ttatttagtt tattatgttt ccggtagttt ggctgcaggc tttcttactg caatggtcca
      841 agttatattg gaattaaagc ttggtgatat gtttcaaaaa catatacaag atctcacagg
      901 gattccatta gtaacagtga ctcattttat gacatctgcc gctgtcttgt tgctgccttt
      961 caatatgatc atggataaaa ttcctgcttt aaataaacga gcggatacga atgcattgaa
     1021 gaagaaaatt gggatcttct ctgaaaactc tgtaatggga ttcattattg gattggggct
     1081 tggctttgct gctgcgtatg gcgtttcagg ttctcttaat ctagcgatcc aaacagctac
     1141 agcattaagt ttgtttccta tgatctctaa aatgttcatg caatctttgt ctcctctagc
     1201 agacgctatg tcagaattta tgaaaaagcg gtttaaggat cgtgaagtat atatcggatt
     1261 ggactggccg atattagctg gtcgttcaga aatttgggtt actgctattt tacttgttcc
     1321 tgtgtttatt ggttatgcca ttattttgcc aggaaaccaa gtattgccat tagcagggat
     1381 tatcaactat tcgattgcgg tcggcggatt acttttaaca ggaggaaact tggctcgtat
     1441 gctgatcttg ggaatcatca ctatgcctat ttatttgtac ggggccactt accttgcgcc
     1501 aatactcagt gatttagcag aaaaaagcgg agcagtcgag ggaatcaaga aaggacagtt
     1561 gatcacatgg tcatccatag aagggccgga gttcagggtt ttatttgcgg aggcatttaa
     1621 taggaatatt ctcgctattg taggatgcgt gatttttcta ggactgtttg ttctacttta
     1681 taaatatatg ataaaagcga aagtaccgag tgaacgttat gctgaactac aaaaatagca
     1741 ttgaaatggt gggaaagtaa tgaaaagaga agagacagat aaaataaaat ggacagtcgc
     1801 tctttgtggt acacttctgc tatttctata tggactcttt actcagaata tcatcatcaa
     1861 tctattggtc atttttttcg cactagtgat ctataaatat ggaaatcacg ttttattcag
     1921 agagtacgat gaaaaaagaa aacggaaaat agaagaatca atgaaaataa aagaagctac
     1981 caaagaaata ttgagagaaa aaagttttat aaaaagataa tggaggggtc attatgtcag
     2041 atggacgtat gttatttgag agagaacgac aggacatggc acgtatcgta agagtgattt
     2101 tcgaaaggaa aaacacaaat gtcgcaggag ggaatttttc ctttaaaacc actgatgatc
     2161 aagggaaaga ctacatcatc atgacgccga ccatgatgtc agaagcctat ctaggagaga
     2221 tttctcctgc acaggttcta gtagtagaac caagaacgcg tagaatcgtt gacggagtcg
     2281 gtcatttaac tcgtgaaatc aatatgcatg aagcgatgta tgagactaat ccagctatca
     2341 aagctgtcct acatgctcat gcgcctaatg caatgttctg ggcgactact gggttgccta
     2401 tgcctaattt gacagaagcc acagctaaag taaaagagat tcctgtcatg gactttgagc
     2461 ctaattgctc tgaagaactt gctgaattga caagcgacta tgtaaaaaaa cagcatctcg
     2521 aattaccgca tatgttgctg ctcaactctc atggcgtatt gatcaacaca ggtggagaat
     2581 caggaatcga agctatccat aaagcactgc aaatccttga tacagttgaa tggaatgcag
     2641 aaattgccta caagcagacg atttttcaag cattagggat tactgacggt ttttattcaa
     2701 aaggtgagaa aatcggggga ttggaagagt tgaaacataa aacggctatt tataataaat
     2761 ctgttattgc agctggtgga gactaaccta tctgacacaa aaaactacga ctttcacaaa
     2821 atctgatcca gatcgatatc tgcttcaggt tgtattatgt aagtcgtagt tcttttcttt
     2881 tatttagtta agaggtggtc tgtccattcc ctcgcttgct tgatttcgtc catcgtcaac
     2941 tgatgacctg ttacagttag ctgaatagtc acatttgctt ggcgtgtttc gaattgatcg
     3001 gccaattctt taaaggaagc aggggaaacg attggatcgt tatcaccata agaaatccag
     3061 acggttttat cctctaatgt ggaacggctt tgatgaacac ctagagacat cggatggaaa
     3121 aacaaccctt tatttagctc ggtctcacgc tccaataata aatgagcagc gatgtttgcg
     3181 ccatttgaat agccgacaag cagccagtca cttaacggta tcagttcttt ttcgctgatt
     3241 tctttgattt tttcatggag tttatctgtt tctttttcca aactgtccag gtcgaattga
     3301 ttcaatccat tacgcttgaa aaaacgattc atcccatctt cttggaccgt gccacgaaaa
     3361 gaaagcaatg tactgtttgg tgcaagaaag tgagcgatat ccagtaaaga atgttcatcg
     3421 ccacctgtgc catgaagtaa gatcaaatgc ttgccacttg ttcctttttc aaaaatgtag
     3481 gtcattttgt tccctctttt ctgtttctat agatgcaaat gaagtagcat gaagagatta
     3541 ttcacgtttt ttatttgcat cacttgtatc gaaaggacgg acataagctt caatggcttc
     3601 acgacgttct tctaagaatg gaggaagaga tagtttttct cctgctgatt ctgctggttc
     3661 atcttcaagg aatccaggac catcagttgc taattcaaac agtacgtgat gagcggctag
     3721 gaagtactca gattggaaat agaaacgatc gacgaaacca gaatttggca attcaatctt
     3781 attgattact tgaatccagt attccaatgc ttctttgtct gctacacgca atgctaagtg
     3841 atggatattt ccaaatcctt cgattgcttt tggcaagtct gtccgatgtt caataatgat
     3901 gcttgcacca tttccccctt caccgatttc aaataagtag aaatctcctg aatggtctgt
     3961 ttctttgaat cctaagattt tttcaagaat caagcggata tgctctaatt gactgacacg
     4021 gacaaagaca ggtccaagtc ctgtgatcgc aaactctgtc ggtacattgc tgtttttcca
     4081 aggaatgcca gctgctacac cttgattgtt ttcgtcagag atcaattgat aatactgatt
     4141 atcgaaatgt tcaaattcga tatatttttt gccgaaacgt tcattgattg ctgaatgagt
     4201 aacgtcatat ttttcaaaac gttccaacca aaagtctaat gctgcgtcac ttggcacacg
     4261 gaaagaagca cgagagatcg tatctgttcc tttttttcct tttggctgat ttggaaaatc
     4321 aaagaaagtc atatctgttc ctggcgcacc agtatcgtct gtaaagtaaa gatggtaagt
     4381 ttcgatgtca tcttggttaa ctgttttttt gattaagcgc attcctaaaa tatctgtaaa
     4441 aaagcggtag atttttgtag cgctagatgt cattgctgtg acgtggtgaa ttcctctgat
     4501 ttgtgtatcc atgataaatt tcctcctgtt aacttacaaa aagtaagtag ttgatttaga
     4561 catagtatag agggtgcatc tctattttgc aattaatttg tcttctaaag tatcaggaag
     4621 gaatcaagaa tggaaaagag gagggacgga tcaataaaat aaaaagactt acgactagct
     4681 gtatcgattt caaaaaaact agctttaaaa agctaacttt agaatcatta cgggtggtca
     4741 taagtctttt tatgctgagt tattttttca tttttgagct aatgcttagg atagaataga
     4801 atgttgattt cacgatctct tcttgttact tgaaactgct taccactgtc acgatctctt
     4861 ggtaaacggc tttttcacaa cctctttggt taagttgaac gcacatccag cacagaatag
     4921 ttccgaacat caaatcggtt tcggctggaa gaatattcaa tcggctgtcc atctttgaga
     4981 tagacgactt gctgaacttc cagtacagga tcgttttctg cacagttcaa atattgctga
     5041 tcatattcat cacttttatc tgcagaaata gcacgataag cccctgcaaa atggacattc
     5101 aattcttgat gaagatgatc atagatagag gctaacaaat gttctttttt taaacccggc
     5161 acaagatgga ctggcataaa ggtatgctct aaaacatatg gctcgccatc taagatcctt
     5221 aaccggtgaa tattgtagac aggttgctcg gcatcgatca tcaatcgttc ttggatatat
     5281 tgattaggga attcaacatc aaaatgaatg atttgactct tcaaagaacg atgtctgcgt
     5341 ttcatttgga gactcaaacc ttcatactcg ttagcgggcg atgtgtcttt ttgcataaat
     5401 ggatgattca agattttcgt tcctgatcct cgctgcgaat agacaagtcc ttccattgct
     5461 aagatattga tggctttttt gattgtcatc cggctcgcac caaattcttt taccaagtcg
     5521 acttgattag gcaaaaaact atcgagagga tactcttttg aacggatacg ttctcttaaa
     5581 atatttgcga tttcttcgta ttttggcacg ttattcacct cttctagagt ataacgaaag
     5641 attatgcttc cgacaactcg aagtagcatc tggaacattg tttattcgaa aaaagaggtc
     5701 atgacaagtt tttgtcacaa ccccttaatg atctattaag caatatctaa atctggttgt
     5761 ttatctagta ctttcaggaa tgggtaccag ataaaggcaa cgatgacaaa gtcgatgact
     5821 tgcagcatac caccaagcca tgaatttgtt gctaagacac cgcttgcaat gattggcaca
     5881 gtccatggaa cagagacgcc agttggtgca gggacaagtc cagcagccat taccaaataa
     5941 ttgaacgtcg ttacgattag aggtgccaca acccaaggaa taaggattgt tgcattcaat
     6001 acgatcggta gaccgaagat cgctggttca tttacattga aaataccagg tgctaaagct
     6061 aatcgtccaa catcacgata ctgtttcttt ttaagaacaa aggccatcaa taaaacgaca
     6121 gctaaagtca ttccagagcc accaatacca acagtgaagg tttccatgaa tggttttgtg
     6181 atgatgtgtg gtaattcttt tccatgttga taagcttcta agttatcaag catcagtgta
     6241 ttccaaatcg ggtccattac agagttgacg atgatttgtc cgtgaagtcc gaagaaccat
     6301 aagaattgga caaagaacaa agcaatcaat gttgcaggta aactacttcc caaaccagtt
     6361 aatggttttt ggatcacttc ataaacgacg tcatgtaagt tagcattgaa aataccagtc
     6421 atcacagcat tgattactaa gaaaatagtt agtgtcacta cagcagggat caaagcggca
     6481 aatgattttg ttactgcagg cggaactcca tcaggcattt tgatctgcca gccgcgtttc
     6541 gtgattctgc agtagatttc tccagccaag aaagcagcga tcattccaat gaacattcct
     6601 tttgcgccaa gacgatcaag tgaaagcaca ccagtcacat cttcaccgcc agcggttttc
     6661 attgcaaaag gcgtaagaat caagaagctg gcaaaagaca cggcaccacc gaaaatacct
     6721 tcaacgtcat aagattttga taaataatag ccgataccaa aagtaacaaa aaccgacatg
     6781 atgctcattg ttgcattttg cccattaccg aataaattcg ataaagttcc ctttgttgcg
     6841 tcactgaaaa aaggcaagtt attgataacg acaacgatcg aaccgaacat cgttaaaggg
     6901 aaggaaagca tgaaagcatc ccgcagcact gtaaggtaac gattttgccc taataaatta
     6961 gctaagggca tgattttctc agaaagcttg tccataaaac cgttcatttt tattcacctc
     7021 aaatttattt gcaatcgatt acatacaaag tataacgcca aaaattttaa atgtctagtc
     7081 attttcataa aaagtattga tttatttttt agggttcgtt atgattacgg tatcaagaaa
     7141 aaagagagga agtaaaaaaa tgaaaaccta cacattccca gaaaattttt ggtggggttc
     7201 tgctgctagc ggaccgcaaa cagaaggaag agtaagtgat gatggtaaag gagaaaatat
     7261 ttgggatcat tggtatgaat tagagcctga aaaattcttc gatcaagtag gacctgaaaa
     7321 aacttcgcaa gtttacacaa aatacaaaga agatgttcag ttaatgaaag aaactggcca
     7381 taacacattt cgtacatcta tccaatggag tcatttgatt ccagaaggga caggtgaaat
     7441 caatcaaaaa gctgtttctt tttatcgaga ttattttact gaattgctgg ataatggtat
     7501 tgaacctttt gtgaaccttt accatttcga tatgccacta ccactgcaag aaaaaggcgg
     7561 atggttatca agagaaacgg tcgacgctta tgtttcttat gcagcagcgt gctttgaact
     7621 gtttggagat ctggtcaaaa aatggtttac tcataatgaa ccaatcgtac ctgtagaagg
     7681 aggctacttg tatcaattcc actatccaaa tcatatcaat atgaaagaag cggtccaagt
     7741 aggctatcat gagaatctag caagcgcaaa ggtaatcaaa gcctaccatg aaggcggaca
     7801 tgatggtgag atcggaatca tcttgaatct gacaccaagc tatccgagag atgaaacgaa
     7861 cccagaagat gtaaaagcgg cgaagatcgc tgacgcattc ttcaaccgat cattccttga
     7921 ccctgcagtg aaaggagagt ttccacaaga gttgatcgaa attgtcaaag aattggctat
     7981 aatgccagag atccatgaag gagacctaga actcatccgt gaaaacacga ttgacctgct
     8041 aggaatcaat tactatcagc ctcgtcgaat caaagcaaaa gaaactccaa tcaatcacga
     8101 acatagcccc atgccagatg attattttga taattacgac atgcccaata aaaaaatgaa
     8161 tccatatcgt ggatgggaaa tttacgaaaa aggaatctat gatattttaa cgaatacaag
     8221 agaaaactat ggtaatatca aatgctatat ttctgaaaat gggatggggg tcgaaggaga
     8281 agaacgattt gttaacagcg aaggaattat tgaagatgat taccggatcg agtttgttac
     8341 ggatcatttg aaatacgtcc atcaagcaat ccaagaagga accaattgtg tgggttacca
     8401 catgtggaca tgtatggaca actggtcttg gacaaatgct tataagaatc gctatggctt
     8461 tatcgctgtt gatttggcac aagacggtaa acggacgatc aaaaaatcag gtcgctggtt
     8521 taaaacggtc tctgaaaaaa acggatttga tgcctgatat tttttgataa aacgttcaca
     8581 aaatgtttgt tctaacactg taatcgtgct acactaacag tgaaggaggc gtttacaatg
     8641 gtagatactt atcgtaatat tttagtagca attgatggtt ctgaaaaggc agaaaaagca
     8701 tttcttgagg caatcacgat tgccaaacga aatcaggcaa cgttgcacat cctgtatgtc
     8761 aatgaagtaa caggcaatta ctttggtgat tttgcatttg ttacaacaag ccttcaggaa
     8821 gaattggatg aggttgcgga aaaccagatg aaagaacatc gaaacttggc aattgaaaaa
     8881 ggcctgacag atatcgagac atatgttctt tacggttatc caaagacact gattgctaat
     8941 ttccatgaat cgaaagaacc aatcgatctg attgtcatgg gggcgacagg tctgaatgcg
     9001 gtagaacgtg cactagtagg ttccactact tcctatgtag tcaaccacgc atcatgtaac
     9061 gtcatggttg taaaataaat aaattaaggg aacagaaagc aaaaaagcat aacgcttctt
     9121 ttgctttctg ttccttttat ttttttgtaa aaaattactt tacctgatga agtaatcatg
     9181 ctattctaat tacaacgaca gatggagtaa tatggaggaa agaaaatgat ttcaagtgat
     9241 ggaatacgcg gatacaatga tgcgattatt ttatcgatcc ttaacaaaaa cgattcttat
     9301 ggatatgaaa tttctaaaac gattcgtgag aggacaaatg attcctatgt gatcaaagag
     9361 acaacacttt actccgtttt tgcccgttta gaaaagaatc aactgattgt ttcgtatcct
     9421 ggagaagtga ctcatggaaa aaagcggaca tattataaaa tcactgaaat agggcgtaat
     9481 cttttagaag aaaaaaagca agagtggctg acgacgaaag acgtagtcga tcaatttttg
     9541 gagggaaatt aaatggatac aatccgtaat tatttagaca gtctttttat cggagtacct
     9601 caaagtaccg agatagataa gctgaaaact gatttgttgg caaatatgga agaccattat
     9661 catgaattga tgggagaagg aaaaaatgaa caggaggcca tcggtacagt aatttcgaca
     9721 tttggttcaa tcgatgaatt attagaagaa ctagatgtcg aaaaaaaaca tcaagctgac
     9781 gagacggaaa caaacacagc ttctatttat ttaagcgaag cagaaaacta ctggaaagaa
     9841 tacagagcgg caagtctcca agtggcatca ggtgttctat tcattagctt atcttttgca
     9901 agttttcttt tcttttgttc agcaggatat gtgttcatgg gtatttcttg tctgattttc
     9961 ggtatagcat tagctgtcgg tttttttatt gcttctggta tgaaaatcac acgtttaaat
    10021 cactttttgc accatcggaa aatacctgaa aaagtattag cagaagcaaa agaaaaagaa
    10081 gaagagtatc agcgaagttt tggcttctca ctgattgcag gaattggatt atgtattttt
    10141 tcacttttcc cacttttggc ttctttaatg tggtatatgg atggtagtat cggtgcctct
    10201 atattttttg ttacggtagg aacgggtgtc ttcttgatca tttatggcag tctagtccgt
    10261 cattcttatc gtcaattcac tcaaagcgct tattactggt gaatgtattc agatttgtaa
    10321 aaatattcta tttatccggc gtagaaaaaa agactgtgac acgcttttgt cacagtcttt
    10381 tttatatata ataatttaaa aattcatcat ctaaatccgt agaattttct agattgctta
    10441 cccatgtaaa atcgttatag acagatttca gttgacttct gcgccattgt acagggataa
    10501 aaagacgcat gctatcttca ttgaatccga ctaataattt ctttccgtca gtaatgatgg
    10561 gacgttgtaa caaagtaaaa tgcgagacga tcagatcgac aagctctgag gtcgtacatt
    10621 ggtcgatttg gtctttcaaa tttttataat caatcgagcg tttagctaat agatcgtcaa
    10681 atccgttttc tgttaatgac aataaataaa atatctcttt ccttgttaaa ggctgtttag
    10741 gtgtgaaaat tcgttctctg taaggcattt gatggtcttt cagccagttt gccatcagat
    10801 ggtaactatg tgtgcgagaa gaatagatcg taagcataaa aaaactcctt aaatagtcca
    10861 ttaatttgtt agatctgttg agataaataa taggtaagga gctgtgcata agcattgatc
    10921 aaaacaaccc aaacatcatt agaaataact ttctaaagtc ttaaacttgc gacgagaaac
    10981 aactagacta atagaaaaaa tgtcttagcc atttggcttc ctgtttgttt ttttgcttat
    11041 gctgcagctc ctcgggaaag ggttctaaca atttgaagaa ggttgatgat tgatctagtt
    11101 taaattgtgt gaaatttgaa atctggtgtt tttactagat gaatcaccta acaactatga
    11161 ttataactta tagaacttct gttttgcatt cggttttgtt atagttgtta taaagtttta
    11221 ttttattaca gaacattttt aattaataaa gaacagttag aagttaaaat tgctgattca
    11281 catagagttt atgacttctt ggaaattctt tttcaatcag ttttttcatc tgtttatgaa
    11341 attctttttt ttcagtaaac ataaaggttt gggtatcgta accttcttca tgtaggaaat
    11401 agattattcc tttttctgtg ttttgcgtat aagcttttat actcctgtct tttttgaaag
    11461 aacagatcgt atagccatct atttggtctg gtagtcgttt gattttcttc aaaatgactt
    11521 ttttatcctc aagtttcatt tttttcacct gactttattt ttttcatatg gaaatcatag
    11581 cgcctttggt tatatgaaaa caagaaggat actgaaatat atataaatca aatagtggtt
    11641 atttattatt agaatagcga atacaaataa acgaccacta ttttctgatt tattgcaaat
    11701 gttttttcaa ataaatttga ttaccaagaa aaggtagtgg tatatttact gagggatact
    11761 ttgaaaaaca tatgatagaa acagtaacag tattatgaaa aatcttttta taaaaatgga
    11821 ggaatcgatt tgatggaaga tcagtatgta caagcaatga cgatcgcagg atcagatagc
    11881 gatggaagcg cagggatgca agcagatatg catacattct ttacaagaaa tgtttacggt
    11941 gtttctgtca tgaccgcatg tgttgcaggt aattcttacg gaatcggagc aagtgtgaca
    12001 ttgccaacag attttatcga caaagaattt gaactgattg cgaaggactt tcaaatacgt
    12061 gcagctaaaa caggtatgct agcagattca aagttgattg agacagttgt aaaaaattac
    12121 caaaaatatg attttggacc attagtcgtg gatcccgtaa tcgtaacgaa acatggaaat
    12181 cttttactag aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc tttggccgaa
    12241 gtactgacac ctaattttta tgaagcagaa aagctgactg gacggacatt agcagctgaa
    12301 gaagattttg tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa cgttatgatc
    12361 aaaggacatc atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt attgttcgaa
    12421 tcaggaaaat cattttggtt aaatgcacca ttttatccta ccgaccggat caacggaact
    12481 ggcgattcgc tatctgcatg tattgcagct gagttagcga aaggaaaaac agttgaacaa
    12541 gcgatccgat tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat aaatgtaggg
    12601 cacaaatatg gccccatcaa tcattgggca gctggtgaat tagagtaaaa gaaagaagtt
    12661 gtgaaaaagt tgccctgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt
    12721 ttttaacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    12781 ggtcgtgagc ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa acagcttctc
    12841 atgtttgttg aatattgtga cttgtgaccg aggagttggc aggagaacac cgtttgttcg
    12901 gaagaaggga ctgtgacaag atttttgtca cagtcccttt aatcttagta tatttttctc
    12961 tacttgaata aaaaaattat aggattggag aaaataatcg agaaatttgt tgcttgaata
    13021 atagccagtt agacatttcc ttgactgttt cagttgtcat ggatgaacaa tgtgtctcat
    13081 cttctttgaa ctgagtagca agttcttcta aaaactcagg atcgtaaatg acagcacttg
    13141 tttcaaaatt caatcggtag ctacgaatat cttgatttgc tgaacctacc atgcagattt
    13201 catcatccat tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca aggatttgta
    13261 cattttcctt gatcagctgc cgagcataat attgtgttgc tcgataaata aaaggatgat
    13321 ccggtttgtt gggaatcatg attttcacat ctacaccaga ggcagttgcg atttttaaag
    13381 cagcaatgac actttcatca ggaacaaggt aaggtgtctg tatccaaaca cgttttttag
    13441 cagaagtaat caatttgata aatgaaagct tgatttgttc cctttcgtta ttcggtccgc
    13501 ttgaaacaag ctggatggat gtatcagcaa gcttagattc atctcgatct gcttttttaa
    13561 agaaataatt caaatgatag ccgacctttt tttcttcagg taccgagacg ttccagtctg
    13621 ttaagaagcg aagctggagc aaagaagaag cggcaccgaa aatccgtata tgcgtatcgc
    13681 gccaatagcc gaattttttt gttgtattta catattgatt ggcaatattg aaaccaccgg
    13741 tataactaat ctttccatcg atcacaacga tttttcggtg atcatggtaa ttcaatcgga
    13801 aacgaagtaa tgccctttgt gaggtaacaa atgtatggac atgtccacca tttttgatta
    13861 gacgattgaa atcttttgct tttgtgccat gagagccaaa tgcatcatat aatattcgaa
    13921 cttccacgcc ttctgcggct ttttcttcta aaacatgtaa gacttgctgg ccgatattat
    13981 ctgtcacaaa tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt agatcttgaa
    14041 gcagtgaatc caatttctct tgtccgtctg tgagaagagt gacagaattc attcttgtca
    14101 gcggcatacg atttaatgaa gagaagaagt caacaaattg ctgtttgtct ttatcgccca
    14161 tgtcaggatc gtaatgttca atggtatctc ctctaaaaga ctgaaagttt tctaattctt
    14221 tcaagtcact ttgtcggaga tagaattttt tcttatccgt taatccacgt ccgaaaaata
    14281 aatataatac aaagcccacc ccaggaaggg caaacaatac taagagccat gcccaaatgg
    14341 ctgctacatc tcggggtttg atcaaaatag ccaccaaagc aataagtgca tttaatagat
    14401 aaagggcggt tataatacta gataccacaa aaatgttcct ccttacatac aataacatta
    14461 gtatagcatg atagaagaaa gaagcctacc aaggtgaata tacttttcac tcctttcatg
    14521 aaaatgtagg taaatcgggc taaagtagtt gctttttgta ggttaataag gtaggatatt
    14581 agtacagttg aatatctcct taggggagta accggcaacg tttgttgcga taatatcaac
    14641 agtaagttaa ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta agacaaatgc
    14701 gtatttgtct taggtctctt ttttttcaga caggactagg gccaagatca aaaaatgggg
    14761 gatgaaattt ggaaaacaag gaacaagcac aacaagcggt ctataaagaa acgatcgact
    14821 cgttgatgca gcaaacgcag agctcaaccg atggattgag caccacgcaa gcgaaggaaa
    14881 aattagaaag agatggcttg aaccagctaa aagaaaagcc gaagaagcca acttggaaat
    14941 tgttcttaga aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc gcactgattc
    15001 agatggtcat gggtgactac atcgaattct tagttatttt tgcagtattg atgttgaatt
    15061 ctataatcag tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg ttgaaaaacc
    15121 tttcagcgcc cgatgctcga gtgattcgtg atggtaagga aaaaacgatt ccggcaaacg
    15181 aacttgtggt aggagatatc gtgttgttag acgcaggcga ttatgtacct gctgatggac
    15241 gtttactaga tgcgggatca ttaaaagtag atgaaggtat gctgacagga gagtcgactt
    15301 ctgcagaaaa agaagtaacg gatatcacaa gtacggtacc aatcggagat cgtacaaata
    15361 tggtattcag tggaacgatc gtaacttacg gacgcggtaa attcttagtg acttcaactg
    15421 ggaataatac ggagatcgga caagttgctg gccttttgga atcaacaact gagcaagtca
    15481 ctccgttaca acgaggtctg gataaattca gtaaaaaact aagtttggct attttggcat
    15541 tgtctttatt gattttaggt atccaactgt ttcgtattta tcttggagaa ggtacaggag
    15601 atatgactgc agatatcgtc agcgcagtga tgtttgccgt agccgtagcc gtagctgcta
    15661 ttccagaagc attacagtct atcgtaacaa tcgtgttatc tttgggaacg aataaaatgg
    15721 caaaacgtca tgccattatt cggaagcttc cagcagttga aacacttggt tcgacaagta
    15781 tcatctgtac agataagact ggtacattga cacaaaacaa aatgacagtt gttgactact
    15841 ttttaggtaa tggcgatact ggggatttca caaatgaccc ttcaaaatgg acagctgacg
    15901 aacgtcgctt gatcgaaatc agtgttttag cgaatgatgc atcgatcagt gaagacggta
    15961 ctaaattggg cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa ttaaaccagc
    16021 cttatcagga aatccgaaac aactacccaa gacaagcaga acttcctttt gactcagatc
    16081 gaaaattaat gtctactgga cacacaattg ataacaaaaa ttacttgttt gttaaaggcg
    16141 gaccagatat cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa gtcgttccga
    16201 tgacggatga attgatgaaa aaattccaag agcaaaatga agctttttca acacgcgcat
    16261 tacgtgtact agcttttgct taccgtccac ttgataattt tgatttatca tttgaagatg
    16321 aagacgattt gatccttgtt ggtttgcttg ctatgatcga tcctccacgt gctgaagtga
    16381 ctcaggcggt aacagaagca agaagtgcag gaatcaaaac aatcatgatt actggtgacc
    16441 acaaaacaac agctgttgct atcgcaaaac aaatcgggat ttttgaagaa ggaaacctgg
    16501 ctttgaccgg gacggaacta gatgaattga cagaagatca actaaacgaa gttttagaaa
    16561 aagtcactgt ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt cgtgcttggc
    16621 aaaataaagg tcatatctca gctatgacag gtgatggtgt aaatgacgca ccagcattga
    16681 aacaagcaga catcggaatt gctatgggaa cgggtacaga tgtggcaaaa gatgcagcag
    16741 cgatggtatt gacggatgat aactttgctt ctattgtcag cgcagtagaa gtaggacgta
    16801 atgtgtttga taatatcaag aaagctattt cttatctatt tgcaggaaat ttaggtgcga
    16861 tcattgcgat catctttgcc ttagttgctg actggtccaa tccatttaca gcattacaac
    16921 tgttgttcat caatttagtc aatgattcac tgccagcaat tgcattaggt acagaaaaag
    16981 ctgaacctgc tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc tttacggaca
    17041 aaacattgat ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt atctttgctc
    17101 aatggcttgg catgcagcat tcacctgaat tcggtgtagc catgtcattt tcaacattga
    17161 tttggtgtcg gacattgcaa acattcccag cacgttcaaa cacacaaaca gctatccaag
    17221 cagggttctt ctctaacaga agtgtcttac tagctgtagt tgtatgtagc gcgctttact
    17281 gcttaacaat gatcccagga ctgaaagaag tcttctctat cccatcagca tttggattga
    17341 cagaagtctt tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg gaaatcacta
    17401 aattgatcat tgtacgagta caaggaaata aataaaacga atcaacgagg ttgtgagcct
    17461 gccgtttaat tctgagtcac aaggtgcaat ttcaacaaac agcttctcat gtttgttgaa
    17521 tattgtgact tgtgaccgaa gagttggcag gagaacaccg tttaaggaag aagttgtaaa
    17581 atcagcattt tgagctaata ctgagggtca tctgattgga cactgtttat tcggaaagag
    17641 ggactttgac acgactttgg tcacagtccc tttttttatt tatgatagac ggaaagccaa
    17701 tcattttatt attcatcaaa agagatagaa tagataaaag aggagaatga tttattccga
    17761 aaagtgaaaa catataacaa aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg
    17821 aatttgctga agaatattat gaaatccagc aagaatcgca agtaactatt gctgaagatg
    17881 taaaaaatta tctgaaaacg gagaaagtcc tgcctgctga aacagcagca gacgttgctg
    17941 gaggatctgg cagatttctt tccttagcaa aagaaattaa tcgctatgat ttgatcgatt
    18001 tttcttcagg aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg
    18061 tttcctttat caaacagtcg ttagaagaat ttatccaatc aaatgagaca tatgaaatgg
    18121 tttttacagc agcaaatcca gcattggtac atcttattca attagaaaaa ttgatgaaaa
    18181 agtcaagcaa atggtgcgtg ataatcagag tagtggaatc aatcgatgat gttttttatc
    18241 ctatcgaaaa gcaactagga atgatagaag aagatcctaa tacatcgcca gttgtaatgg
    18301 atcaatttga aacatactta attgatgaag gattcaaagt gaagaaaaaa gattttactt
    18361 attttacaca ggaatcaatt actgaagaat tgatgaagct atactatgac gcgtacgcaa
    18421 aagatcctgt tgtgaccagg tacattcgca aactattcag tgaaaaacga gaaatcctta
    18481 gtacgactaa gctgacctat agactgctcc tttggtccgc agataaaaaa agaacctttc
    18541 acgactcgtg aagggttctt tttatgattt tattatattt tgtagtaacg aatatcattt
    18601 tcgatctttg taatcgaaaa aggtacatct gaagtatatt ctgcacattc tccgtgttca
    18661 ggaagcgtct cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct
    18721 agcatctctt gatgagattg tgcgaagaga tattcttgat agttttcttc cagataacct
    18781 gtaaaaaatt cacttactgc accagaaccg tagctgaata gaccgatgcg atctcctggc
    18841 tgtagtgatt tcgaattttc cagtagagaa gttagcccca ggtataatga accagtgtaa
    18901 agattaccga ttcgtcggct gtaacggatg ctttcttcat agcgagccat aagacgttcc
    18961 tgattttctt cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc catcttagta
    19021 tacggaatat ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga caattcttta
    19081 tgtcgattcc aaactttttg gaatgattcg atatacgtag aattagataa aggaccatca
    19141 acaacaggaa attcgctata atctggacgc cagaaatcat agatatcttc tgtcagaaat
    19201 acgctgtcgt cttcaatcga taaaatacgc gggttttgag tgatcatcat cgcaacagca
    19261 ccgacacctt gcgtcacttc accaccgctt gccaagccgt aacgagcaat atcacttgct
    19321 atgactagta cttttcgttc tggatgattt ttgacatatt ctttcgccat gtgcaaagct
    19381 gcggtgccac cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga ttggattttc
    19441 agtaaatggt ggataattac cgcactcgct tttgaatgat caatcccgga ttctgttccg
    19501 acgatgacca tgtcgattag ctcacggtct ttttctgtta cgattttgct ggcagcattt
    19561 gctcctagtg taatgatgtc ttcatttgca cgattgactg ccatttggtc ttgaccaatc
    19621 cctatatggt attttgcagg atcatcccca cggctttctg ccaactctgt catatctaaa
    19681 tataaattag gaataaaaaa ggaaagacga tcaatcccta ttttcatttc aacacctctt
    19741 tacttatgat aaaaaactta ctttactaag gtatcataaa aagattaaaa gaaatataaa
    19801 aaagagaata tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag
    19861 ctatttgttt ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa
    19921 gtcgttatga tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca
    19981 tttactgcag ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg
    20041 aaaaaagata aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa
    20101 aatgttgcca gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg
    20161 atcaatgaag tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa
    20221 ttaggtgaag cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg
    20281 ctgaaacagt atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac
    20341 gacggattga ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca
    20401 acacaatttt ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa
    20461 gcagcacatg ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct
    20521 gatgaagacg tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg
    20581 ggcacgttac gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg
    20641 ttgaatgacg gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat
    20701 ctgccttatt tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg
    20761 ggaatcgctc caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca
    20821 acaatcgatc tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa
    20881 gaactgcagt tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat
    20941 ccaattggtg caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa
    21001 cagaagagat acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg
    21061 ttagaagcga atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt
    21121 acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg
    21181 ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa
    21241 gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa
    21301 aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca
    21361 aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt
    21421 ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag
    21481 ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa
    21541 gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta
    21601 gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca
    21661 aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt
    21721 gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac
    21781 aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt
    21841 gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg
    21901 gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga
    21961 aatggattat accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa
    22021 ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca
    22081 aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct
    22141 gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa
    22201 aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag
    22261 gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct
    22321 atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag
    22381 caagatttac agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg
    22441 tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa
    22501 gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga
    22561 caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa
    22621 attattatat gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat
    22681 ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat
    22741 ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata
    22801 gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt
    22861 tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa
    22921 cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt
    22981 tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc
    23041 gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga
    23101 agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca
    23161 gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct
    23221 aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca
    23281 taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat
    23341 gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt
    23401 cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa
    23461 aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga
    23521 aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt
    23581 ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag
    23641 ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt
    23701 gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg
    23761 gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata
    23821 aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc
    23881 atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt
    23941 attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag
    24001 cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat
    24061 ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc
    24121 atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg
    24181 attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa
    24241 attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca
    24301 tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat
    24361 caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat
    24421 cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct
    24481 aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc
    24541 agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc
    24601 cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag
    24661 acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata
    24721 agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt
    24781 taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa
    24841 gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa
    24901 actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat
    24961 tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca
    25021 gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt
    25081 gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca
    25141 gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc
    25201 aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc
    25261 ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct
    25321 gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa
    25381 aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa
    25441 aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa
    25501 tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg
    25561 ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct
    25621 tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta
    25681 caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa
    25741 ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg
    25801 gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa
    25861 tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa
    25921 ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt
    25981 gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg
    26041 gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta
    26101 attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct
    26161 taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg
    26221 ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg
    26281 cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc
    26341 attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa
    26401 acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt
    26461 cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac
    26521 agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact
    26581 atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt
    26641 ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt
    26701 tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat
    26761 aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat
    26821 tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca
    26881 cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg
    26941 cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg
    27001 gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat
    27061 tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga
    27121 tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat
    27181 tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt
    27241 agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga
    27301 atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca
    27361 aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat
    27421 cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc
    27481 aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg
    27541 tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt
    27601 agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt
    27661 acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat
    27721 tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg
    27781 tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac
    27841 aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat
    27901 tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga
    27961 aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact
    28021 cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt
    28081 ttggaccgct ctttgttctt caattgtata agaagagatt gtagaagcat gaactttcgt
    28141 tttacttcag tctcttttat tcatcatgag agtgttcatc tatcggtatg cagtttttaa
    28201 tactttcttc gtatccattt tttcaaacca cttattctac cttgtgtctg ctcaactggc
    28261 gcattatcaa taatcagcaa agcaatcata acatatgcaa tccaactatc tctagaatat
    28321 agagtataac gtgagaccca gtttgtagcg tacttgcttt tatattctct taatccatgg
    28381 aaagaataaa aatgagaacc aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa
    28441 ctctttctgg aagttccgac atttgaaaga ggggccatcc ctaaattgaa ccattggata
    28501 tgttcttctt tcatataggc aaacaaatgc aagaacaaga aatccatact gccagaaggt
    28561 gcttttttag aatcatatcg catcagatca atcgttccta ctttattgtt cgtgtaagta
    28621 ggcatgatcg ttgcaaaagc gacaatttct tcttgggtat ttttgacaac tgcaataggc
    28681 gctctttgta gataatcttc agagaaaaag cctaaagaaa accctttttc ctttcgtgaa
    28741 cccaaccaat tatcagagat atttttgaaa gtactcattt gctcagtaga aaatggtggt
    28801 tgtaagacat caaatgtaaa tccttctcgt tcgatccgat tcaagacagc acgagtgccc
    28861 ttcatttttt tccctgaagt tgtaaaacta ttcaggtcta cataagcttc ttcccccatc
    28921 ttaatgaaat cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag
    28981 aaaactggta aatagcatag tcgatctgtt tcttcgataa aagcttcgat tgcttctgga
    29041 aaatcttctt tcttaccaga aggatcaccc attacaatac atttattatt gaagcaagcg
    29101 aattggagaa gaacagttgg ttcaccgtct ttttcatagg caaacatccg cttatctttt
    29161 aagaagatca attgactatc ggagtttcct ccataagttg taaggatctt cagggccttt
    29221 tcttcattaa aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg aacaaataga
    29281 acgatcatga aactaacagc gatgatggcc aacaatcccg aaaaccaaat cttttcagaa
    29341 ggaaataaga aaaaggaaat aaaatggtga cgccgatgag ggaaatctgg cagattgtat
    29401 accccaataa cgatgtaaag caaggacagt gcaccaataa tgattccatc gatcgtacgc
    29461 cactcccatg aatagatcaa ttgttcccga aataattcgt ttttagaagc aagaatgatc
    29521 agaagcagaa tagacaagaa aaccaccggt gtgaaactaa aatcacttaa taaaacataa
    29581 agtaaagcta gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg
    29641 atccctctgc ccataatgat taaaagaaat cccaatagta tactaggaaa ttggataata
    29701 aaatgaaatt tcaatgggtt caaactatga agccagcgaa actctgtaaa agcttgcggg
    29761 atagtggcag aaagtactag catgattcca gaaaagtata ataagacaac cacgatttta
    29821 tgcgcaattt ctgttgctaa ttgtttaggg ataccagaat aacgctgatc aaaagtggaa
    29881 ccgatatttt tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta gtagaacagg
    29941 cgatagagca agatccacac aacgactatt tctcttggca caccaatagc ggacaacccg
    30001 ataatcatca ttacatcgaa actcccaatt tctcctggaa tcatagacac gattcctatc
    30061 actgaagcag caatgaataa tggaattgtt tgccacagat caatccggat ttccattaaa
    30121 taaccaacag aaaggaaact aaacaggaca ccggtccatt ccaacaatga aactagcaat
    30181 agctgtcctt gagttttaag tgaggtacca ccaaggaatc ctttcttttt gaaagtagta
    30241 aataaaaaga cgacaggaaa atatagaccg ccgccgatca accatatcca atattgcttc
    30301 aaaaaaggag caactggcgt gaagactaca agtaaaaaag aaagcagact gtaaatagaa
    30361 agtccagcca tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt tctgctctct
    30421 ttcttttgtc catatagttc agagcgaagc cccacactaa caaacccgcc gaaaccggca
    30481 atattgttga tcgtattgat cagccagctt gtctcaaaca ggtaacgagg attctgcttt
    30541 tgttcaagca tccgattcaa aataatatca taaccaacca taggtaacac agagataaga
    30601 ccaatcaata gcattagtcc gcttttccat acaggtatag tggcaaacgt ttctcctaat
    30661 tgctggatag atagagtttt accgatggac atcaattcac cgacaataat gacaatgaca
    30721 gaaatcaaaa agattgtttt gaacagtcct aggtggtttt tcagccattg tatggtattt
    30781 tttaacaaat aaatcacctt ctattcctaa tagttatgtt tcagaaagaa attgaagaac
    30841 ttctcgattg aagcgttcag gatcttttct agctaattca tgtccttgtt ctttcacaag
    30901 cacaaaggaa gcttttggta tagttttagc tatatacaaa gaatgtttta gcttgattac
    30961 atcttttttt cccacgatga tcaaagtggg ggagttgatt ttttttaaat cattttctgt
    31021 aagcccgatg tcatgcagca aaagtttgat aactaaaaga tttttgcgaa gacttgggcg
    31081 aaataaagag agtaaccata cccatgcata atgaatatta ctgatgactc tggcagaaaa
    31141 acgaacgcct ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa cttttttagg
    31201 gaagctgctg gcaaatacca gtgctagatt tgctccatca ctaaatccaa gaaaatctgc
    31261 ctgatcgatt ttttccagca acatgatcgt attcagatcc tcggccatta actgaaaatt
    31321 caacatagat gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta gatacacggt
    31381 atagtagcgt tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc
    31441 atgcagtaaa aagagaggga agccttgacc gctcttttca tagtaaattt cgctcccatc
    31501 tggcattttt gcatatttct tttctttttt cacataatca cctactgtgt aaagtataac
    31561 gattatatca gtcattgggc aattgttttt actgaaaaac aacgatcatt ttcgtaagat
    31621 gtcaaaaaat acaggaaaat tcattttttc ttaaggcgta cacagaaatc aaggaagaaa
    31681 tagccaagaa gataaagaaa tagtaagata aaaaaagatg tcaaaataac taggtgatga
    31741 aatgaagcga aaacgattat ctattatccg tattcttttt tacatgatca ttctgacggt
    31801 tattggtgcg gtgttgtttt taggaggaag aacttatcgt tcggtaaaac gagtggaaag
    31861 ctatcaaata gaaataacaa cagctgcaaa aaattatcat atggaaaact acgagaattt
    31921 gatcaaggcg ataatattga ccgaatcaaa aggaaaaggg acagatctca tgcagagctc
    31981 ggaaagtctg catggagaag ctgagatcat tgataatcca gctgacagta ttgatcaagg
    32041 tgtcaaatat ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg atttatggac
    32101 agctgtccaa gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg
    32161 agaaaacaca gtagaattag cagaagcgta ttctaaagat gtgctgagcc cacttttagg
    32221 aaatgaggaa gggaaacaat accgatattg gcggatccag tccttgcttt acaatggcgg
    32281 ctatctctat cataatggag gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa
    32341 aataatagag acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt caatcatgaa
    32401 taaaattaaa tgaaagaagg agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc
    32461 aagaagtggg gtacacaacc aaagactgga tgttacggtt tgtgaaggga atgtttatcg
    32521 gttcaggatt tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt
    32581 atgagcggct gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt
    32641 tttttctgcc tgttggtcta ggcggagtga caggcatctt tctactttct tttttagtca
    32701 gttttttatt aggtgcgtat gaaacaacga tattatggtt ttttgtcgga tgtatcgctg
    32761 gaactgttcc tgcgttatgg aaagaagcag ggaaaaaagg aagagatact tctgatgtga
    32821 tcatcatggt tgttactttt gttctggctt atttgttttt attatacggc gctcaattat
    32881 ttgacgggca agtcgatcag aattttggaa catggctgat tgccggcgga ttgattggtt
    32941 tgggtatgat cgtcccagga ttgagccctt ctaatttttt ggtgtatatg ggattgtata
    33001 aagcgatggc tgacggattt aaagaagtac gacttgaagt gattgtgccg atcggaattg
    33061 gtgggattct ttgtgttctt ggattgtcaa aaatcatgga ttacattttc tcaaaggcat
    33121 atagcaagct attccatttc attttaggtg tagtttttgc ttcaacgatt atgatcattc
    33181 ctaccgatta cgcgggattg ggagttgctg gggtactagc ttgtcctgtt ctttttatag
    33241 ccggtacagc actaggttgg tggatgagcc gtttggagga acaatataag taaagataga
    33301 ttgataataa aaacagcaca cgggtgattc aaacaaaaag gttggcatct tttttgtaaa
    33361 atcattcgtg tgtttttcta taaattttat aaaaacaagt tgtttttaat cttggaacac
    33421 gctagactta aacacgtgat tatttttgaa agttggcgga aaatggagaa aaagaaaatg
    33481 aatggactta cacagcaaga ggtagttcag aaaatggctt ctggccagca aaatgactac
    33541 caggaagatg catcaaaaag tacaaaacaa atattcagcg ataatatatt gacgttattc
    33601 aattttctga actttggtat tgggatttgt ctgttatttg taggtgcgta ttccaacatg
    33661 gcgtatttag caattattgt cgtcaatatc gttattggaa tttatcaaga aatacatgca
    33721 agaaatcttg tacggaaatt atcgattgtt tcccaatcag aagtactagt gatccgggac
    33781 ggtaaagaac aatcgatttc tactaaagag ctggtattag gagatttggt aaaaatcgga
    33841 gcaggagaac agataccagc cgatttacag gttatatctg gacgggcaga agcaaatgaa
    33901 gctcttttga caggcgaatc tgatttgatt gtcaaagaaa ctggagctga attgctttct
    33961 ggaagctttt tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg tgcagataat
    34021 tatgctgtcc gcttgactag cgaggcaaag actcacaaag ctattcgttc tgaacttgta
    34081 gattcgattc gcaaagtatc caaattcact agtttcgtga ttattccttt ggggatcata
    34141 ctatttttgg aagcactgtt catccgcgat gcttctatca aaatttctgt tattgcatct
    34201 gcagcagctt tgttaggcat gcttccaaag ggtttggtat tgctaataag tattgcatta
    34261 acgacagggg taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt
    34321 gaaacgctgg cccatgtcga tacattatgc ttggataaaa cagggaccat tactgaaggg
    34381 aaaatgagta tccagcgggt agaagcacta catccgctgt acgagaaagc catcccagaa
    34441 attatgggga cgtatctggc agaaagcagt gataacaaca tcactatgcg ggctatgaga
    34501 gattattttg agctttctaa tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat
    34561 cgcaaatggg gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa
    34621 cgtttggtgg aagaagatcg gcttccggac agtctaaaaa cagcccaagc gaatggctat
    34681 cgcgtactta tgttggggat cgctccaaat cagcaattga acgaagaaaa accagcattt
    34741 gttgagccgg ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca
    34801 ctagcttatc ttcatgagga aggtgtggat ctgaaagtga tttctggaga caatcctttt
    34861 actgtctcca atatcgctag acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt
    34921 tctcaaatta ctgaagaaat ggaagtgcga gaagctgctc atcgctatac ggtttttgga
    34981 cgagtgagtc cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg
    35041 gttgcaatga caggcgacgg tgtgaatgat gttttggcgt taagagaagc agattgcagc
    35101 attgctatgg cagaaggtga tggagcaaca cgtcagattg cgaatctggt attgttggac
    35161 tctgatttta ctacattgcc agaagtcctg tttgaaggac gccgagtggt caacaatgtg
    35221 acgaaagtct caggcatctt ttttatcaaa acgatttatt catttatttt atcgattata
    35281 tgtgccgtta cagcaattgg atttccgttt atccctatcc aaatcacgct gattgattta
    35341 gcgattgaag ggtatccttc cttcttttta tcttttgaac aagataaaag aaaaatcact
    35401 taccgttatt tgcctacagc acttattaat gctttaccaa atgccttgct tgtagtagtg
    35461 aatatcattg cggtgtatct acttggaaaa acattcgcat ggggaaatgc tgaaactact
    35521 actttgatgt attacttgct gattgggatc agttgcatgg cagttgtaaa agcttgttat
    35581 cccttcaacc cattgcgcat cttcctagca gtaacgacga tcgtagggat atatgtagct
    35641 gcaatgctgt tccatggaat tttggaagta aacttagggt tgggagagag cgtaggatac
    35701 ttctttgtat tcatgctcgt aaatattgtt cttcgagtat tgtactggaa ggctgatatt
    35761 caaaatcagt tactgaaaag agtagcaaat tgatgcttaa tgagatagaa atgtgttata
    35821 cttgaaaaag caatgaaata tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg
    35881 cactgatttc agttagtgcg attttttacc ggttattctc ctgaaatatc ttctgttaaa
    35941 cccaaaagat atcaatagag cagggggtga aaaaatggct caacggattc ctcaagaggt
    36001 tatcgaaaca gtacgcagtc aaacgaatat cgttgaggtg attggacaat atgtccagtt
    36061 gaaaaagtct ggtaaaaatt acttggggct gtgtcctttt catgaagaac gtacaccgtc
    36121 tttttctgtt gcagaagaca agcagatttt tcattgcttt ggttgtggta aaggcggaaa
    36181 cgtgtttact tttcttcaag aactagaagg tctaagtttt ccagaagcag tggtaaaagt
    36241 ggcagacttc gaacagatac cgttagaaga tcaatggcgt cagcgtacta tagctgtcca
    36301 aaatcctgaa tctgctacgg ggaaactgat tgctgctcat gaaaaagcag cggaaatcta
    36361 tcatcacatg ctattgcata caaaagctgg acagccagct ttagaatatt tgcaaagtcg
    36421 tgggttgtct ttagaattaa ttgaagaatt caacataggt tttgcaccta atgagcgttc
    36481 ttttcttcag caagtattca agaatgaatc aatttcaaat gaattgttag aacgctctgg
    36541 attgtttgtc acgcatgatg atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt
    36601 tccacttcgt aattctcaag gccagacgat cggtttttca ggacgctggc ttgcacctga
    36661 aaaagggcag gaaaaagatc agcccaaata cttgaatagt ccagaaacag aactgttcaa
    36721 taaaagacaa gttttattta atcttgataa agcaagaagc gatatccgga aaaacggaga
    36781 aattttgttg ttcgaagggt ttatggatgt gattgctgca tggcaggctg gtatcaaaac
    36841 tggattagct tctatgggga caagtctaac agctcaacag atccaacaaa tggaaaagct
    36901 gacgaaagaa ttggtctttt gctatgacgg agacaacgca ggttttgaag caaccaatcg
    36961 agggattgaa ttgcttcggc aaaacagtcg attagcactt tctgtcgtag tcgttccaga
    37021 aaagcttgat cctgatgaat atctccgtaa gtatggagaa gcatctttcc aagaattagt
    37081 ggctcatggg cgcgaaacag tctttacttt taaatcacgt tatttaaaac aagggaaaaa
    37141 tttagataat gaaaaagaca agatcgaata cctcgaagaa ttactagttg aacttagccg
    37201 agttgtttca ccaatcgaac aagatatgta tctatctcaa ctgtcaacag agtttcagat
    37261 cggcagagag acgatacaaa aacaactgcg cgatcttcga aggacaaatc agcaaaatcg
    37321 tcaagaacct caggaaagtc aacacactca ggttacgaga caagaaactg cacggaaaaa
    37381 gagacctttg acgcaagtag aaaaggcaga gcagattcta ttatatcgtg catttaaaga
    37441 agtttctgtc cgtaatattt taaaagaacg agaatttcag tttattcatg atgcatatgc
    37501 agaagtttat tttttattcg atgcatatgt ctcacaacat tatgaattca accttgcaga
    37561 gtttttagac tttttgcaag atgaaaattt aaggcggttg gtggtggaaa tcgaatattt
    37621 accggtggca gaagaaagtt cgccacgaga aatccaagac ttgctagatg tgatcagcaa
    37681 atctggctta gctgatgaaa taacattaaa aaaacaaatg cagcaagaag ccagacgaac
    37741 tggaaacaaa cagcttgagc ttgaattgac gattgaaatc atcaatttaa cgaaacagtt
    37801 aaaacaagcc aaatagctac tcaagggggg ccttctttta tggcaaatgg aacagataaa
    37861 aaaacgtatg aagcagcagt agcagctttc atcaaagaaa acaaacccaa acgacaagtt
    37921 gtatatgatg atttatccaa tcagcttgct acaccattca ctttgaatgc agatgaaatg
    37981 gacaaattga tccaaaagat tgaagacgca ggtatcagtg tggtggatga aaatggtgat
    38041 ccatcaattc acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa aacagaagat
    38101 ctttctgcgc caaccggtgt aaaaatcaat gacccggttc gtatgtatct gaaagaaatt
    38161 ggccgtgtct cccttttaac tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa
    38221 ggcgaccaag aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc
    38281 gctaaacgtt atgtaggacg aggcatgcag ttccttgact tgatccaaga aggaaacatg
    38341 ggactgatga aggcagttga aaaatttgac taccgcaaag gatttaagtt ttcaacctat
    38401 gctacatggt ggattcgtca agccatcact cgagcaatcg ctgaccaagc acgtacgatc
    38461 cgtattccag ttcatatggt tgaaacaatt aataaattga tacgtatcca acgtcaattg
    38521 ctgcaagacc ttggaagaga acctacgcca gaagaaatcg gtgcggaaat ggatcttcca
    38581 acagaaaaag tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct tgaaacgcca
    38641 atcggtgaag aagatgactc tcacttaggt gatttcatag aagaccagga agcaacaagt
    38701 ccagcagaac acgcagctta tgagttacta aaagaacaat tggaagatgt actagataca
    38761 ttgactgatc gggaagagaa tgtccttcgc ttacgttttg gtttagatga tggccggacg
    38821 agaacattgg aagaagtagg gaaagtgttt ggtgttactc gggaacgtat tcgtcagatc
    38881 gaggctaaag cattaagaaa attgcgccat ccttctcgtt caaaacaatt aaaagatttc
    38941 ttagaataag cgtggactat tgaccagaag agaaatcagt aaaactgttt ggtttatttt
    39001 aaaagaaaaa aagcttgaga ctacgcagtc tcaagctttt ttttctatag gaaggaaatt
    39061 cattcattat ttttaagtaa atcctaaaaa taagctattg gcgtgacgta tagaatatga
    39121 tagattaaat ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt
    39181 ccaaattgcg gatcgaaaaa aatggagcag aatactatct gtccagactg cggtcatcaa
    39241 ataactgcag aagatcagca aataaaagaa tcaattgaag aaacaaatac agatgcagct
    39301 atgcaggata aatcaactga agatgcagtc tttcctgata cagaattaaa cgatccaatc
    39361 gaatggtcgg aattgaaaga tttacctcta gaatctgtaa tggaattatt cgaaaaagca
    39421 gaaccagaag acgaagaacc acctgctcac gatcaagtaa ctaatataga gaaaaatgaa
    39481 cagaagaaag caactgttca tgagacttcg gaagaatcag gaaagaatca agaagaaacg
    39541 cttgaatcaa aacaaaaaag aagagtagct gaactgaaag aaatcgtcga taatgaggaa
    39601 gaaaattcga tactatccgc ttatatcaaa gcacatcgtg aagatacaaa agaagagcac
    39661 gcgaaagagc tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa agtagagcca
    39721 gaaaaggaac aagaaactga aaaagactct gatagagaaa acgccacagg taaagaaaca
    39781 gtaaaaataa aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt tactgaaaaa
    39841 caattagaaa aggaaaaaac gaataaactg ccggaagcag agaaaaaaga aatactcgaa
    39901 aacacagaca aaaagtcaac agagcccgat gaaataaata gtgaatccga tgctgaaaat
    39961 caatctgtaa gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga agagaaccag
    40021 cctaagctgt ttgaagcaga agcgaaatca ataacaatcg tgccagatac tgaaaaaaca
    40081 catcaagaat caaacttaga aaaaacagat ccagataaag cgcaaaagaa aaaatcaaaa
    40141 aaagtacctt atctcgtttt agcagcagta cttctactcg gtggaggaag ctgggcttat
    40201 tatgaccatc atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag acagcaacaa
    40261 atggaagaac ttcatgagaa acttgctgcc ttttatacag atgatcacca tcaatttatt
    40321 cgtgcagata tgattcatca agatttatca aaactaaaaa atgatttatc cagtcttaag
    40381 aatgaaaaag gatattcaga gttagaaaca acttaccaag atatccaatc taagatccga
    40441 gatatccaaa aagtgaatga gtggttcata gcacctgcca tcgtcgatga tcatctagca
    40501 gatgacatca agttgaaagc agataaagag atccaagcaa tcgaaacgga taacacagat
    40561 tttggaaaat tgattcaaca agcacaaaca gaagctaaaa atcaatatgc tgaattgcaa
    40621 acagctaaag aaaaaacagc tatagtcttt aaagacggaa aagtagtgga ttcagcaaca
    40681 cgcgaccaat acaagacggc aaaagaagca gtagaaaaag tgaaaaatac agatctatct
    40741 gctcagttga atgaacaatt gaaacaagta gataagatgc tcactgataa agagaaaaaa
    40801 gaagaagagg aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga acaagcaaaa
    40861 caagccgctc aagcagcagc tgcagctcaa gccgctcaac aagctgcggt cgcacaagca
    40921 gcacagcaag aagcggcatc ctcgacccct tcctcttcaa actcagcgaa tcagccaatc
    40981 aaatctgcca gagcaagtga tattgccgat gcatctaatc cagcatggac gtgggcacca
    41041 ggtgtccaaa gcaaagtgat tgctacatgt atccaacgtg gatatatcgt tgaaggaggt
    41101 tacagattag aaaaagccag aatcgaaaat ggggaaggct attataatct atatgccact
    41161 tcaacaaaat ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta
    41221 accatcaact gtaaaactgg atggttcgga ggaaatggga gcaattaatt ttaggcaaat
    41281 gaaagaggct gtgagcctgc cgtttaacac cgtttattcg aaaaagggga gtatgacaca
    41341 actgttgtca tactcctttt ttcacctttc caaaccaagg ctcagctatt caagtagata
    41401 acattatgtt atgatagcaa agaaatgtat taagaaaacc tttcactata gagggagaaa
    41461 aaaatgaacg atttattagc aactatattt acaggtatta ttattgatga aaatgaaaaa
    41521 aactactttg tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga aggtgaacac
    41581 aaaatcggtg aagcagttga aggattcggt taccaaaatc aaaaacatga aaatcggatc
    41641 actacacaaa ttcctaaaag ccgtatcggt cattacggtt ttggaatcgt tactgctaca
    41701 cgaaaagatt taggtgcgtt tgtcgatatc ggtcttccag ataaagactt tgtcgtatct
    41761 cttgatgaat tgccgacaat gacagagcta tggcctaaaa aaggggatcg cttgatgatt
    41821 tcccttagag ttgatgcaaa agaccgtatt tggggcagtt tagcagatga aaaaatattc
    41881 aaatctttaa gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat aggaacagca
    41941 taccgcttga aattaacagg tacgtacgtt ttaacggaag atttctatct tgggtttatc
    42001 catccttctg aacgatataa tgaacctcgt ctaggcgagc agataaaagg tcgagtgatt
    42061 ggtgtccgac cagacggtgt actgaatctt tcattgaagc caagagcata tgaagctata
    42121 tcagatgatg cacaaatgat tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac
    42181 tttacagata aatcggatcc agaagaaatc atgaaagctt ttggtatcag caaaggagca
    42241 tttaagcgcg cattaggtaa tcttttgaaa caaggattga ttacacaaga aaacggtgtg
    42301 acaaaactag tcaaaaaatc taattgagaa tcccttgcat gtttttctta actagcttat
    42361 aataatttta attaacatag tgttatatct ttttttattt gtaattatta taaattgttg
    42421 gggttgagta aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa cagcagctac
    42481 atgaagcggg gtttaagctg acaccgcaaa gagaagctac tctgcttgtg cttttggaaa
    42541 atgagaaaga gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg
    42601 aaattggact tgctactgtt tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg
    42661 ataaagtaag ttttaatgat ggattagccc gttatgattt gagaaaagaa ggcgccaaac
    42721 atttccatca tcatttacta tgcttgaact gcggcacgat cgaggaagta gaagaggatc
    42781 ttttacttga agtggagcaa gtagtagaag aacgttatca ttttttagta aaagatcatc
    42841 ggctaacgtt ccatggaatc tgtcaggaat gctatgaaaa agaaaaaaga aaccagtccg
    42901 tctgagtgtc tagacggctt tttctttgct cagattatgg aaaaagacta tcagaatgaa
    42961 gcggtatctg atatgataga gaggcatgag ggggattatt atgaaagagc aaatcaacga
    43021 ttatctccac tacttgaata ttgaacgggg attgtccgcc aatacacgac aaagctatga
    43081 acgtgatttg gaacagtact tgcattttct acaggagcag aaaattgctt catggcagga
    43141 tgtcgatcgc tttttagtca tccgttttct ggagaagttg catgaagaaa aaaaagcgac
    43201 agcaactgtt actcggatga tctcaagtct cagaagattc catcagtttt tacggcaaga
    43261 gcgtatcact gatcatgatc cgatgcaaca tatcgatacg ccgaagaaag cacagaaatt
    43321 accaagtaca ttgactctga cagaagtaga aaagctgatt gaagcacctg atacgacaaa
    43381 aacgttaggg ataagagatc gtgcaatctt ggaagtcatg tatgctactg ggatgcgcgt
    43441 cagtgaattg attggattga aattgggaga tcttcatctt tctcttggac tggtacagac
    43501 agttggaaaa ggagataaag agcggatcat tcctttaggt gattatgcga tccaatggct
    43561 ggaacgctac ttagacgaag cacgtccatt acttgtaaag gacgcatctg aaatgcatgt
    43621 atttgtcaat aatcatggga aaggtctttc tcggcaagga atctggaaaa atctgaagca
    43681 gttagtacga gaggctggga tttacaaaga agtaacacca catacgctgc ggcatagctt
    43741 tgccacacat ctgctagaaa atggagctga tttgcggaca gtacaggaat tgttaggtca
    43801 cgcggatatc tctacgactc agatttatac acatatcacg aagaaaagaa tgacggatgt
    43861 ttataagcag cattttccaa gggcttagtc ataggaaggt gagaagatgt taacacatta
    43921 ccggaaagaa aaccgtaaaa ttgctatggg actattgagt ttccataaga aactgacagg
    43981 taaaacttct ttgttgaagg agattgatac gtacgaatct gaagacgatt atgaactttt
    44041 tttctttacg ccagaaggtt caaccaacat tcaagggatt attggtattt actgggcaac
    44101 gaacgatcag ctgatcatcc atgacatttc tttgaatccg tcttatcgcg gtgagaatat
    44161 gggctttcaa atgttagatg aattacagga aaagtacccg gatgtctcca tccgtgcaac
    44221 tgaaatcaca gagccttaca ttggaaaatg gctagcaaag aaaaagaaga aagagtgaat
    44281 gagttgacgg agatcaatat taaattagat gtattcgagg gtcctctcga tctgctgctt
    44341 catctgattc agcaaatgga aatcgatata tatgatatac cgatcgctac gatcacggag
    44401 caatatatga attatatcca tacaatgaaa acactcgagc tagctgttgc aggagaatac
    44461 ttagtgatgg ctgctacatt gatggcaatc aaaagcaaga cattgcttcc tgtccaagaa
    44521 ttcgtcacag acgatgaaga attatgggaa gaagatcctc gagaagaatt ggtcactcag
    44581 cttttagaat accgtaaata taaatatgca gctgaaagac tgacagaaaa agcagaggaa
    44641 cgaagtcttt attacacaaa agaacctatg aacatcgatg ggttagcgga tgctgaaaag
    44701 ccgttgaagc gaggacaagt caaaaaaatc gatttgatcc gtgccatgca gaaaatctta
    44761 gaacgtaaga aattttctca aaaagtggaa aaaacgatca cgcccgatga cacaacgatc
    44821 gaagaacgaa tggtatttat cgaagagcgt ataaaaagaa atgcgcatgg ctgtactttc
    44881 gattcttttt ttgagtcacc ttctaaaagt gaagttgtca ctacttttat ggctttgcta
    44941 gaattgatga aaaaagggca gatcattgcg caacaaaaag aaaactatga atcaattatg
    45001 ctttatccag cagtaggaga taccgaacat gacgaaatta agtgaacttg aagcccttct
    45061 ttttattgtt ggcgaggaag ggatcagtaa tgaagaatta agcggactgt taaatctcag
    45121 cgaagcagaa gtcacaagtt tagtgaaaga attaaaagaa tcttacactc aaaactcgca
    45181 ctcagctttg catatttttg aaacggaaag ccattatgta ttaacgacta aaaaagagct
    45241 ggctccctta cttaagcgat atgcgcaagg gacatcaaac acattatctc aagccgccgt
    45301 cgaaacctta gcaatcatcg cttataaaca gccaatcaca agagctgaaa tcgagcagat
    45361 tcgaggagtt caggtttcag gagcggtaca gcgtctagct gcccataaac tgattgaaga
    45421 aaaaggtaga gtagaaggac caggtcggcc gatattatat ggaacaactg gctacttctt
    45481 agattatttt ggtttgaaat cattagaaga actgcctgat acacaagaaa tggaaatttc
    45541 acttgaagaa gacgtgtcac cagatctatt ctttgatgga atgaataaag gagaataatt
    45601 gtaatggaga gattgcagaa agtaattgcc cacgctggca tcacttctcg tcgaaaagca
    45661 gaagaattca tccttgcagg acgtgtaaaa gtaaacggac aagttgtaag ggaattaggg
    45721 ataaaagttg ggaaacatga cactgtggaa gtggatgaag tcccaattta tcaagaagaa
    45781 tacggttact atttattgta caaacctaaa ggagttattt ctgctgttgc agatgacaaa
    45841 ggaagaaaag ttgttacgga tcttttgccg atggtaaaag aacgtatcta tcctgtaggt
    45901 cgactggatt acgatacttc ggggatcttg ctactgacaa atgatggaga ttttgctcag
    45961 cgcctgacac atccaaaaca tgaagtggat aaagtttacg ttgcaaaggt aaaagggatc
    46021 gctacaaaat cgatgcttgc acctttgaca aaaggaataa agatcgaagg acgaaaaaca
    46081 tctccagcta aattccaaat tttatcagtg gatcctaaga caaaccacag tatcgtggaa
    46141 ttgacgatcc acgaaggacg taatcatcaa gtgaaaaata tgcttcaagc agttggtctt
    46201 cctgtgcaaa aactaaaacg tgaaaaatac ggagatctga ctttacaagg cctacgtcct
    46261 ggggattacc gtgaactgaa caaaaaagaa gtcagcagtt tgctgaacca ctcaaaatga
    46321 acacttactt tttataagtg ttagatgttg cgttttttga atagatatgt ataatgaata
    46381 tgtaaacaaa aattatataa ggttcgtctt caggggcagg gtgaaattcc cgaccggtgg
    46441 ttatagtcca cgacctattt tgcaaaaaaa tagctgaatc ggtgaaattc cgataccgac
    46501 agtatagtct ggataaagaa gatagagctt atttgacgac gcttgatcaa ataactctaa
    46561 ctctattttc cctggaaaat agagtttttt catttggaga gaaacgtcaa aaagttcgct
    46621 gaagaggagt cctaacagga ggatttcaaa tgaagaacac ccgtgtacag aaaatggttg
    46681 cagtagcgat gtttgctgcg atcgcattag ttttacagta ttttgctttt ccgatcatgc
    46741 cggcttttag ttttttgaag atcgatttta gtgatatctc ggtattgatc agcatgttct
    46801 tattcggtcc agcggccgga gttgcaacag cgttcttgcg ttcagtatta catctgctga
    46861 ctacaggttt ttctccggat aatttggtag gagacactgc tagtttctta tcaacaacga
    46921 tctttacatt cccgatttat tatttcttta gtgtaaagaa acagcataaa ggaagaaaca
    46981 aatttttagg tgtcattaca ggaaccatcg ctctaactat ttttatgagt atcgcaaatt
    47041 atttcgttat tacgcctctt tacttaatgt ttttagggct gaacgcaaca cagatgctgg
    47101 gcatgtcttt agcaaactat gtactgattg ggatcgttcc tttcaacttg atcaaaggat
    47161 tcatcgtgag tgctgtcttt ttagtgctgc atgcgcaact tcttccatgg ttaagtcgaa
    47221 aacaacatca gttcgaacaa cgtcatacag cagtcaaata aatatcaaaa agatcaagaa
    47281 atttcttggt cttttttttt ggaaaaaaat acaagacatg caataatgta aacgttttat
    47341 ttgtttgttt tgagtatttt tttgatttat gcataaaaat caatcaattc tttgcaaatg
    47401 tgaaattctt ctccttttaa aagacgaaaa tgtttgttta taaaaaaaag gaaacgctac
    47461 aatgaaaaag aagaaagctt taaaaacctg aaaaaagagg agggaatagg gaaaaacgaa
    47521 ctttttgaac aaaagtttta caaaatgcgt gttattattt ttgttctgat actctttttg
    47581 ataaaataac attagagcca aaattgttgt ctctaacgga aaagaaagga agaagaagat
    47641 ggaacaaaca aaaaagaaaa aatttcaaat gccttcagcg tatacggtct tatttattat
    47701 tattgcagta atcgctgtac ttacttggtt tataccagct gggcactata gtgtagacga
    47761 tgcaggcaac atcgtcgctg gatcatatga acgagtacaa caaaatcctc aagggctgtg
    47821 ggatattttc atggcgccaa tcaatgggat gctaggtgta ccagcggggg agctaactaa
    47881 agaaacacct gctgcaatcc caatctcttt cttcattttg gttgttggtg gatttttagg
    47941 tattatcaac aaaacagggg cactagatgc cgggattgct tcagttgtga agaaattcaa
    48001 aggaaaagaa aaaatgctta ttccagtatt gatgctgtta tttgcattag gcggctctac
    48061 ttacggaatg gcagaagaaa cgattccatt ctatgcttta ctgatcccag tcatgatggc
    48121 tgtaggcttt gatacagtag tagctgtagc aatcgtatta gtagggtctc aagtaggctg
    48181 tctagcttca acggtaaatc cttttgcaac aggcgtagct tcacaagctg ttgggatttc
    48241 gatgggtgaa ggtattggtc ttcgattctt gatgttcgtt attttgttag ctatttctat
    48301 tgtatatgtg tatcgttatg catcaaagat cgaaaaagat ccaacaaaat cattagtata
    48361 caaccaacgt aaagaagata tgaagcattt cgatattgaa gcaatcggtc gtcaagaagt
    48421 aatcacgaaa aaacaaaaac atgttaatgt attgttcttt attacttttg gtatcatgat
    48481 catcagtttg attccttgga caaccttgaa tgcgaatttc acgatttttg aatcattgac
    48541 aaactggtta acaaaccttc cggtactagg tacggttcta ggtaaaagca tgcttccatt
    48601 aggtgactgg tacttcccag aaattactat gttattctta gtaatgtcca tcgtagtagc
    48661 aatcacttat ggcatgaaag agtctgaatt tgtctctgaa tttttagctg gtgcttctga
    48721 tttgatcggt gtagcaatcg tagtagctgt tgctcgtggt atccaagtgg ttatgaacaa
    48781 tggattaatc acagacacca tcttacattg gggcgaacaa ggattaagtt cattatcttc
    48841 aagtgtattc atcattatta catttatttt ctatatccct atgtcattct tgattccttc
    48901 aacttccggc ttagctgctg caacaatggg aatcatggga cctatgggtg aatttgccgg
    48961 cgtcggtaag gatttagtaa tcactgctta tcaatctgca tctggtttag taaacttaat
    49021 tacaccaaca tctgctatcg taatgggtgc tgtagcaatt gctcgtttcg atgtttcagt
    49081 gtggtggaaa tttaccggta aattaattgc gatattattt gtagccatct gtgtgatcct
    49141 aggtgtagca gcaatgttct aaacctagac aaatacaggt acaaggtcta tcataagaat
    49201 gaagaaaccg ataaacggct atcgataagc acgtggataa gtcaatagct ccattcagtg
    49261 agtgtttttt ctttcatcat ttgttaagaa cattctgctt gctgatggag caggcttaaa
    49321 acgtcattat ttgagaagaa gaggttgtgt cggaggaatt tgacatgacc ctttttaaca
    49381 tattaggagg ataatatcat gaaaaaattt gtgacagaac aacatcatga acaagcatta
    49441 gaatcattga gcgaattgat ccgaattcct tccgtactag atgaagcaga ttcaggacaa
    49501 ggacatccct tcggtaaaaa agtgattgaa gctttggata aagtattgga aatcagtgaa
    49561 aagctaggat ttagaacatt taaagatcca gaaggctatt acggttattc agagattggc
    49621 tctggagatg aattattcgg tatcttgtgt catatggacg ttgttccagc aggggacgaa
    49681 aataattggg aaacaaaacc attcgatcca actataaaag acggctggtt agttggtcgc
    49741 ggatcccaag atgacaaagg tccttctatt gcggcaatgt atgccgtcaa agctttgatt
    49801 gatgctggcg tggaattcaa gacacgtatt cgttttatct ttggtacaga tgaagaaaat
    49861 ttatggcgtt gtttagaaaa atataacgaa aaagaagaag gaattacgca aggatttgcg
    49921 ccagatgctg aatttccttt aatttatgca gaaaaaggct tattgcaagc ttacttgaca
    49981 ggaccaggaa cgaacgagtt ttctgtaaaa gctggaggag cgttgaatgt tgttcctgat
    50041 gcagctcctt actctggaga aaagctttct gaagtaaaag aagcattgaa aaaacacgaa
    50101 ttcgatttcg aagaacaagg tgaaggcatc gtcgttcttg gtaaaagtat ccacgcgaaa
    50161 gatgcagcac aaggagtgaa tgctatttct cgtctggcaa ttgctctttc agaagtattt
    50221 gattttggcc caatcaattt cttaggaaaa ttagttcaag aaaatgcaac tggtgaagct
    50281 gtcgtgggca aaacagaaga tgaacaatcc ggcgagctaa cgatgaactt tgcaagtttg
    50341 gaaatcacac cagaacaaac aaaaatcggt gtagatatga gaatccctgt tacattcaag
    50401 aaagatgatt tagtagctaa attaactaaa acagcagaaa aatatgggtt gacttatgaa
    50461 gaatttgact tccttgattc attatacgtg ccactagaca gtgagttagt gaaaaatcta
    50521 ttggggacat atcgcgatat tactggagac atgactgaac cgtttgtatc aggcggcgct
    50581 acttttgctc gtacgatgaa ccagtgtgtg gcattcggtg cgatgttccc tgatactcct
    50641 gactttatgc accaggcgaa tgaacgatgg gaattaagta gtatgtataa agcaatggaa
    50701 atttatgcag aagctgtgta tcgtttatgt gctaaataaa aataaacata caaaaagggc
    50761 ggatattcaa atggatattc cgtctttttt tatttgatgc tggaaagttt gcatttctct
    50821 cttatttttt taaggtataa tcatacttga ttaagaaaaa ggggtcactc agatagaaaa
    50881 ggtgggagaa agtgaaaata tttagacgaa tactaattgg cttagtcatc attttaggat
    50941 tactcggtgg agccggttat tactatatac agcaaaatac gtacgaacca tcgtcagaag
    51001 cgcaagtgtt ggtaaaagaa ggaaaaaaca aagaagatta cttatttttt gaaggagaga
    51061 aaaagaatca tggaaagtct ccattactta ttttttatcc tggtgctctc gtagagccag
    51121 aaagttatag tatttgggcg caagatttag caaaaaacgg cttttcagtc gctattgtca
    51181 aaatgccact tgatctagca gtgatgggcg gaaacaaagc ggataaggtc aaagaagatt
    51241 ttccaaattc cgattatgtg atcggtggcc attcattagg tggcgtaatg gcaagtcgtt
    51301 atgtcaataa gaatcattca gacaaacatt taaaaggggt attcttcatg gcaagttatc
    51361 ccgacaaaaa aggaacattg acagaatcag ctgttcctgt tttatcgatc acggcgacaa
    51421 aagataaagt attgaatcag gaagcttatc aagaagctaa gcagtattta ccggaaagaa
    51481 cagagtatgt atcaatcaat ggcggaaatc atggaggttt tggcagctat ggtgagcaaa
    51541 aaggagatgg agaggcagaa atttctaacg cagaccagca aactgtgatc gtcaatacat
    51601 tggaaaactg gctgaaaaag ttgaaataat ataaatgggt cctatagggt ccgtgaaaaa
    51661 actagtcaat taactataga tagcaaatga atctttcaaa ataagtcggg atttcacgga
    51721 acaagagaaa cagatcccgg cttattttca agtttagaga acttagtgta cgtttttaaa
    51781 gtttcgttta tatttatatt ttattttcta ataaaatcgc tcgaactgga catttttgat
    51841 acgctttttt tacatatgtt tcttcttccg gcatcacgaa ctgttgatga gcctctggtt
    51901 cttgggcaaa taaaacgatt ccttcttcat cataatcgaa aatatctggc gcttcgattt
    51961 gacaaagacc gcatgcaata cagcgttcag gtacaagttt acatagtagt gacatttcta
    52021 accatcctaa cttaaggaga ataatatgat tgtttttatt ttatcgctat tttcatcagg
    52081 acacaagctg cggattagtt ctctttacca actccttgtg ggaaaacgaa cgacttcagt
    52141 acttatttat ggatttaccc acgaactttt gtttatccat aacagttttc cagaattgaa
    52201 gcaggataag ttttatcaaa ttttgcaaaa aattgcgcag caaggttgga tcgaaataaa
    52261 tgaaaatgaa gcaaagctaa cgcctgcagg ggctgatatg ttgtccgaac atcaaataga
    52321 acatactggt ttgcgttttg accgctatgg cagaacaggg gaaactagtt ggcggctcat
    52381 taaatttgct gttcaagtaa tttctaatct ggcaacgggt attcaagact atcttccagc
    52441 agagacaagt cctttttata ctttccaact aaaaaaatgg cttagtgaaa gccaattgcc
    52501 acgtgaaatt ttgattgata ctgcgtatga gagtttggtg cagctgtttt cggagatacc
    52561 agaagaagca gcagattttt tagctaacca attatctgga aatgagcgaa cagggctgct
    52621 tccttatcag ctggcaaaaa acaatgatga gtcagcggtt tatctgcaac aaagcagatg
    52681 tatccacctt ttgttagcac aaatcgaaaa acggccagat tcgctttggc acgctttgat
    52741 cgattcatta ttacagcaaa atttcaatca aagcatgatg atcaccaagc agatgtttat
    52801 gaatggtcag acaattgacc agatcatggc aatccgtcat ttaaaaagag gaacagtaac
    52861 agatcatctt attgagtggg ccttgttttt tgatgatttt ccatacgagt ggattctctc
    52921 tgcagaaaca atcgaacgtt tggaaccaaa taaggattcc gtgcgagagt ggcgctttag
    52981 cgaatggaat gtagatggac aattagatta tggagaattt cgtttgtatc aaatctatct
    53041 attgagaaag gaagcgatac agaatgttaa taaatgaatt aaaaaaatat tttggatttg
    53101 attcatttcg tcccggccaa gaagaaatta ttcaggcgtt gcttgatgga gaagatactc
    53161 tcgctatttt gcctacagga acgggaaaaa gcctttgcta tcaattgacg gggtatttaa
    53221 tggaaggtct ggtcatcatc gtgtcaccgc tgctttctct aatggaagat caagtgacgc
    53281 aattacaaaa acgaggggag aaacgagtag ctgctttcaa tagtttactt tcgcaatctg
    53341 aaagaagata cgtcctccgt catctatcgc aatataaatt tttgtttttg agtcccgaaa
    53401 tgttgactaa tccttctctt ttagagcatc tgaaaaaaca aaatattgcg ttatatgtag
    53461 tagatgaggc tcattgcgtg tctcaatggg gagttgattt ccgtccagaa tatcaacagt
    53521 taggaaaaat ccgaaagctt ttaggaaacc cggtcacact ggcactaacg gcgacagcaa
    53581 cagatttagt agcaagagat atacgtcatg tactatttga tcgaccacca aaagagatca
    53641 gacaatcagt caatcggcaa aatatctcgc tttttgttcg gaaaacgcag caaaaagaac
    53701 aagaacttga acacttcatg gaaagagcac aaggagcggc aatcatttat tgtgcaacaa
    53761 aaaaagaagt cgaacgattg tatcatttat tcagggaacg ttttacagtt ggatactatc
    53821 acggtggtct tgatgcagct caaagaagac aacttcaaca gcagtttgta aaaaatcagc
    53881 tgcagtttct cattgctacg aatgcatttg gtatggggat cgataaatct gatatccgtt
    53941 atgtggtcca ttatgatttg ccagacagtc tagaaaacta tgtacaagaa atcggtcgag
    54001 caggcagaga tcaggaagaa agtgcagcaa ttctttttta tcaaagtggg gatgaacgta
    54061 tccattattt ctttaatcaa ctttctagag aacagcgaca aagttttgag ctttatttgg
    54121 aatatgccac agagcaagct ccctttgatg agctgcaaaa aaaatggatg gagctgatcc
    54181 agcagtctga aaaaccagaa aattgggtgg aacggctcaa acgtcaggaa aaagaaaaag
    54241 aattccgcct gcagcagatg cttcgctata ttaatgaaga aaactgccgc agaaaattca
    54301 tcttagctta ttttggcgaa aaactctccg aaaagccgca gaattgttgt gatattgatg
    54361 gagcaaaagc agaacttctg ccaaagagga agcttttttc taagactgaa caacttcatt
    54421 gggaaacgat tttactaaat ttatttaaaa aaaacatgga acattgattt tttaggacaa
    54481 gacacttttt cctatggtat aatacacacg atagagttta ggaggtaaaa cagtgagcag
    54541 aaaagataga catcaatcta cagaaaataa cgaaacacaa gaaccatggg aacaaccaat
    54601 ctacgataca gatgatgaag tttcatcaag aagttctcag agacaacaaa agaaaggaaa
    54661 tacattattt ctttcgctat ttttgatttt actggtctta tgtatcgcta ttccagcagg
    54721 tgcttatttc tggatcagaa atggatcaag caacaatgca acagcagcaa cttcttctga
    54781 aacttcgaca tcagtagtag aaagttctac aagtacaaca aaagaggagt caactgagac
    54841 ttcaacagta gaatctagta caatcgcgga agaatctact gtgtctcaag atacaggtgt
    54901 aacgtcagaa agcagtattg cagcagagac aacaccgact tcctcaagtg aggcaactta
    54961 tcaagcaggg gattcaagca gcaatgcagc agaaacaaca ccttcttcat cagctgcagc
    55021 cggttcaaca acgactgttc aagcaggcga aggtccaaaa caagtggctg agcgtgcagg
    55081 gatcaccact gatcaattgt ttgaattgaa tggcttagat ccaaacaact ttatgcttta
    55141 ccctggtcaa gaattaagaa ttaaataata atagccgcgc tttgcggctt tttttctgag
    55201 aaaaaggagt tatatcatga cacaaatcag tattgcaatc gacgggcctg cttcatctgg
    55261 gaaaagtacc gttgccaaga tattagcaaa agaattgaat tatatttata cagataccgg
    55321 tgccatgtat cgcgcagtaa cttatttagc tattacgaac aatgtatctt tttcagatga
    55381 agaagggcta gtttcgctga tcaaaaagta tcctatctct ttttcgcaac aagaagatgg
    55441 acagcatgta ttcatagcat caaaagatgt gactttagaa atccgtcaac cagatgtcac
    55501 aaaagctgtt tctgaagtct ctgcacatgg aaaagtcaga gaagaattag ttgctgtcca
    55561 acgaaaaata ggggaacgcg gtggcgttgt catggacgga agagacatcg ggacagctgt
    55621 attaccgaat gcagaagtga aaatcttttt agtagcaagc gtaagtgagc gtgcagaaag
    55681 acgtttcaaa gagaaccaag aaaaaggaat tccgactgat cttgaaacac tgacgaaaga
    55741 gatacaggaa agagaccatt atgattcaac aagggacgtc tctccgctga agcaagcaga
    55801 ggatgctgtt cgtatcgata cgactggcaa atcgattcca gaagtcgttg cagcaataaa
    55861 agctgttgtt ttgaaaaaag gttatcttct tttttaaatt aagaaaaaaa atgaaaaaca
    55921 attgtttttt caaggaaaac gaacgaaatc gctttatttt ttttgaataa tcaattaaac
    55981 taaaaacagt accgtactta cggcagaatg ttggttagga ggacaagtgt tatgacagaa
    56041 tttgatcaaa atcaagagaa caaccagtca atggaagacg caatgaaaag cgtacaagaa
    56101 gtaaaagttg gcgatgttgt taagggcgaa gttttagtca ttgaagacaa acaagtgatt
    56161 gtcggaatcg aaggggctgg agttgaagga gtcgttccgg caaaagaatt atcaactttg
    56221 ccggtagaag atatcagcga agtagtaaaa gtcggtgatg tattagattt agtcgttatc
    56281 agtacgatcg gcaaagataa agaaaacggc agctatctac tttcaaaacg ccgtttagat
    56341 gctaaaaaag tttgggaaga tatcgaaaga gatttccaag agggcaaggt catcgaagca
    56401 cctgttacaa atgttgtcaa aggcggttta gtcgttgacg tcggtgtacg tggttttgtc
    56461 cctgcatcaa tggtggaaga tcattttgtt gcagactttt cagactataa aggcaaaaca
    56521 ttgagcttta aaatcatcga aatcgaacca tcagaaaatc gtttgatctt atcgcataaa
    56581 gcggtagtgg aaaacgaaag agaagaaaag aaaaaagaaa ttctttcaac tatccatgag
    56641 ggagatgttc tcagtggacg tgttgcacgt cttactgatt ttggcgcatt tgtcgaccta
    56701 ggcggaattg acggtctagt ccatgtctca gagatttcac atagtcatgt agcaaaacca
    56761 agtgatgtat tggctgtcaa tgatgatgta aatgtcaaag tgttgtctat caatcctgaa
    56821 caagaacgtg tttccttgtc aatcaaagac acacagcctg gaccttggtc agaaatcgat
    56881 acaaaagctc cagttggcac agtattagac ggaacagtta aacgtttgac aagcttcggt
    56941 gcctttgttg aagtgttccc tggagtagaa gggctagtcc atatctctca aatttcacat
    57001 aaacatattg cgacaccaca tgaagtgctt catgaaggtg acgaagtgaa agtgaaagta
    57061 ttagagatcc atccagaaga acatcgtatt gcattgagta tcaaagcttt agaagaaaaa
    57121 ccagcttcag aagaagaacc aaaaaatgtt gagtcttatg aattaccaga agaaaatact
    57181 ggatttacta tgggagacat tttaggtgat gcgttgaaag aagaagtaga agaaaaagca
    57241 accgatgatt ctgaaaaata attgattttg tatctgtgac tgagatgaaa gcagctgctt
    57301 ttgtctcagt ttttcttttg aaaagcgatt agtatttcaa taaggaataa aaatacttcg
    57361 tttaattgac aatctatgct tgaaagttgg caatgcattc gttaaactaa gtgagattgg
    57421 aaacttgtga ggaggaaata atatggcaaa tccaacaatt gcaatcgttg gccgcccgaa
    57481 cgtcggtaag tctacgattt ttaaccgcat cgctggtgag cgtatctcga ttgtcgaaga
    57541 tactcctgga gtaactcgtg atcgtattta tgcaaaaggt gaatggttag gtcgagaatt
    57601 cagcgtgatc gacacaggcg gaattgatct tggcgatgaa ccttttatgg atcagatcaa
    57661 gcatcaagca gaaatcgcga ttgaagaagc agatgtaatc atttgtgtag tcagcggacg
    57721 cgaaggcgtg acagacgcag atgagatggt tgcgaaaatt ttatacagaa gtaataaacc
    57781 agtgatttta gcagtcaata aagtagataa tccagaaatg agaaacgata tctatgaatt
    57841 ttattcctta gggctaggcg atccttatcc tgtttcagga agccatggac tagggattgg
    57901 tgatatttta gatgaagcag tgaagtattt ctctgaagag actgaagaag aggacgacga
    57961 cacgattaag tttagtttga ttggtcgccc aaatgttggt aaatcctctt tgatcaatgc
    58021 gattttagga gaagaacgtg taattgtttc ggatattgaa ggaacgaccc gagacgcaat
    58081 cgacacccac ttcgtttctg aaagtggtca gaaattctta atgatagata cagctggtat
    58141 gcgtaaacgc ggaaaagtat acgaaaatac tgaaaaatac agcgtgatgc gtgcaatgcg
    58201 tgccattgac cgttctgata tcgttttgat ggtactgaat gctgaagaag ggattcggga
    58261 acaagacaag cgagtagcgg gttacgccca tgaagctggt cgtggaatta ttatcgtcgt
    58321 gaataaatgg gatcttgtaa agaaagaaac caatacaatg cgtgatttcg aacaagagat
    58381 tcgtgatgaa ttccggtatc ttgattacgc tccaatcgtt tttgtttctg cagtgactaa
    58441 acaacggttg gaacgtctgc ctgaaatgat cgaacaagta agtatgaacc agaatcttcg
    58501 tatctcttcg gctgtgttga atgatatcat tatggatgct gtagcaatca atccaacacc
    58561 aacagataaa ggaaaacgcc tgaagatttt ttatgctaca caagtcgctg tcaaaccacc
    58621 tacatttgtc gtttttgtca atgaagagga attgatgcat ttttcttatg aacgtttctt
    58681 agaaaatcaa atcagaaaag catttacttt tgaagggacg tccatccgaa ttatccctcg
    58741 taggagaaaa taggcatttt accatatcga cgtttttttt tcaaaagaaa aagacagttt
    58801 cgtttgttac gtttctatga ctaaaaaaag catgtgaaaa ttggtaaaaa ccttgctatt
    58861 aagcggttca tatgatatcg tgataacaga atattgaagt taatcaatat ttctttttaa
    58921 acttctggac cactcagaaa gttttaacta aatgatattt ctatcatatc tcttgtggag
    58981 gaggtgaatc tatccatggc aaacaaagca gaattaatcg aaaaagttgc ttcagctact
    59041 gatttaacta aaaaagatgc aactgcagca gtagatgctg tattttcaac tattcaagat
    59101 gctttagcta acggcgaaaa agttcaatta atcggttttg gtaactttga agttcgcgaa
    59161 cgcgcagctc gcaaaggtcg taacccacaa actggtgaag aaatcgaaat tccagctagc
    59221 aaagtacctg cattcaaacc aggtaaagca ttaaaagacg ctgttaaata agacagttga
    59281 aaaagcgctt gtggctctag ggctacaagt gcttttcttt ttatttccta gcagaaaagg
    59341 aataaataag agacagagat tccgaatccg tatgtcatac atagaaaaca catgtatttt
    59401 atttaatttt tatttatttg caagttatga ggtgagcttt gctcttatct tttctagaat
    59461 ttgcttacta atggtaaaat aaaaataaga agaggaggga tgcgtatgga acttgattat
    59521 caagtagaag atgcgttgac gaaagtgttt tacggagaaa cgctagtcag tcagctaaga
    59581 gaactttcca ttgatcagcc aatcttattt ttaacgaatc agcgctatta tgatttgttt
    59641 gcagataaga tcaacccgtt atttgcaaat caagcaaaca atgactggta tatttgtgcc
    59701 aacactcaat gcaatcattt aacagaatta aagaacctgc ttgatttcgt caaacgctat
    59761 cccgaaaatc aatccatgtt tatcatcgga tttggaaatg aagggatcat ggatctggca
    59821 ggtttttttc aaaaacatac aacccttgat tcatcactat ggatgatccc tgtatcgatc
    59881 cgttctctaa gccgagcatt aacaccgcag cggacgattt tgcagctacc aaatcgtgta
    59941 gtgctgcaaa ccatcaatct gccagaacgc atcgtttatg atcaaacaat cagcgagcgg
    60001 caggtggacg gaaagcagat tgactttttg acttttatct gttgcggaat gatttgtgat
    60061 catcgttttt tgcaaaatct gtataaaaac tatccaaata aaaagcaatt aacgactcgg
    60121 ccgtttgccg ggatgatcga agaaatgatc tatttttatc aattagaggc agaaaacctg
    60181 tcaaattatg gtaaactgtt tgaacaagct ttttatctga ccgaaaatgg ccatctactt
    60241 tctgctagta tgaaaaaatt tttaggaatg atgtttcatt tcgtgtggaa tctccaagca
    60301 tatccttttg atttccaact aaaaaacttt tttgtgtggc tggacttgct tggctatcca
    60361 atccactggc tggaacagat ttcaaagatg gagtatttgg aaaaagttct ttttttggca
    60421 gaaaaaagca aaaaaatact tgttttagaa aaaataggta taatagacgg ataccaacat
    60481 ccaaacgaaa aagaattatt gagaacaatg acggtatttc aacaaatcgt cagtgagata
    60541 agagggaatt gaaatgaata caaatagcga aaaaatgttg caagctttat cagatgaaga
    60601 cttgtcacaa gcacaaatct ttttagaaaa agcattaaaa gaagacccag cagatatatt
    60661 agctgaacta ggcgaagaat tgctggctat tggctttttg atcgaagcaa aacagatttt
    60721 tgaacaactg atcaaccaat acccagaaaa tgacggactg aacatcccgt tagcagaaat
    60781 tgcaatcgaa gataatgaga tcgacttagc ttttgaatac ctggaaaaag tggataagca
    60841 aagtgattac tatccgcaaa gcttattggc gatagctgat ttgtaccaag ttatcggaat
    60901 ccctgaagtg agtgaagcaa aattgaaaga agcagctggg ttgcttcctg atgaaccatt
    60961 gatccagttt gcgctagctg aattgtattt ttcagttgat cgtttcaaag aggcagcagt
    61021 ggtttatgaa acattgttgg caagcgggat aaatgaaatt tcaggaatct cgatgcagga
    61081 acgtttagga caatccttaa gtatgcaagg agaattcgaa gcagctatcg tacctttaga
    61141 agaagcactg aaagaagaaa ggacagatga tcgactgttc cagctagctt ttacgaatct
    61201 tcaattgaaa gaaaatcagc aggcaatcaa ctatctggaa gaacttcgag aagttaatcc
    61261 gcattatcaa tcgttatatc tatatctagg acaagctctt caagaagaag aaatgattga
    61321 agaagcacaa acagtgttag aagaaggaat caaagaaaat ccttaccaag tcgaacttta
    61381 tcacctggcc tcggaaaatg ctttccgtct gcatgataga cagcgagcag aagaactttt
    61441 actgaaagct ttagaagtag gagacaaaca agatgaaaca ttacttactt taagtaatct
    61501 ttacttggat gatgaaagat atgaagatgt gatacaagtg atcaatcaga tggaagaaac
    61561 tgctaatcct tatgcagaat ggaacctagc ccatgcttat aatgaattag aagactttac
    61621 cgttgcagct gtacactatg aacaggctta tcatgaacta tcacatgaac cagatttctt
    61681 gaaagagtat gcctttttct taagagaaga agggcagctg aaaagagcgc aagaattatt
    61741 gacttattat ttaacacttg aaccaggaga tatggaggca ctgtcattat tagatgacct
    61801 aacagagagg tgagaaaaat gctaattgat gtacgggaaa agaagaattt tttaacgtgg
    61861 atggtcaatc atgtatcttt tagccgaaga gaagtttttt ggatcttgaa ttatcttgcc
    61921 aatcatgaag cgattttaag caatgtccac tttgttgaag gggcgaattt tgcggatcga
    61981 ggactgcaga tcagtgatct atctgttgaa ggggaaccca tgaaattgtt tttgcaggga
    62041 aaagaattta cggacacaga ccagattttt catgaaatcc gtttgaattg gaaaaagcct
    62101 ttatatgtgg aatgtatatt cgaaaatgct tggcagacaa gagaatatct atctatctta
    62161 gaagacaatc cattttcttc ttgggattct tcagtcagtg aagaagatac tgaattaatt
    62221 gaacgatatt ttcaagaaaa agaagaagag gcaaaactaa aaatgcttta tgctcaaatc
    62281 gatcaagcac tagaagatgg agatagggat gcttttttga aattatctga tgaagttaac
    62341 cgaaagatcc ttttgcagac acaaaagaaa agtaaccggg taagtgaaca taacaattag
    62401 ttaaaaatag tatagtacta aaaaagacaa aggtcagctg gatgtggaat ctttcctcat
    62461 agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg gcttcaaata
    62521 agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag ctttttcgtc
    62581 aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga ccatatagat
    62641 gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca cacctctttg
    62701 cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga caagtagacc
    62761 ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa catacgaaac
    62821 aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa gtaagacgat
    62881 gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt ctaaaatccg
    62941 agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc cgcttcctac
    63001 acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta aattgatttc
    63061 tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac ctagaacagt
    63121 ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg ggatgttgat
    63181 taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca aggtgatccc
    63241 tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac caaatgcata
    63301 aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt tgaccatatg
    63361 aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc cttcctaaat
    63421 gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt aaagttttgg
    63481 taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag tatgcagcag
    63541 gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt agctcagatg
    63601 gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac ttatggagaa
    63661 aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg tgatgtttta
    63721 ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt ttttgaaaaa
    63781 aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga cgagtaaaca
    63841 agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag tcaccatgca
    63901 actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat gaaattaaaa
    63961 caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga gaatgcagga
    64021 tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca gccaatccat
    64081 gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt tccaaaaacg
    64141 atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga acaatatgag
    64201 atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga tcatgtcgaa
    64261 ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa tgcgtttgct
    64321 ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct agaagaacag
    64381 atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt acgaatgatg
    64441 cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac cttctacgcc
    64501 atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa tgtggaattc
    64561 atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat tgaaacagag
    64621 tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg ttttgctgaa
    64681 ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat cagccaactg
    64741 gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc taaccaaatg
    64801 attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg agctttggaa
    64861 ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga attgatgatc
    64921 tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg tttacctatc
    64981 aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac tggaaaaaaa
    65041 cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt agaacaaaga
    65101 ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt gatttaaaaa
    65161 acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat acgtcattag
    65221 aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag gtagtacaag
    65281 aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc gctaaaattt
    65341 tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga tctttggatc
    65401 aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga aatccatccg
    65461 tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac acatgatatc
    65521 aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga agatatcgag
    65581 cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc atatctagat
    65641 aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga aaaaacaggt
    65701 aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg ggaatttttc
    65761 gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt attactactg
    65821 ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag atttttgtcg
    65881 cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga aagtaaacat
    65941 ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata ctatttggaa
    66001 tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg atgaaacaat
    66061 gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg tataggagat
    66121 ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc gctatggcgc
    66181 cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa atatattgat
    66241 gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa aacgtgtaca
    66301 gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa ttttaaagaa
    66361 aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat ggacgatgga
    66421 atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca tagctagccg
    66481 cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg tattaggtct
    66541 gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta tgattattgc
    66601 accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca aaaatttcgg
    66661 gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg taggtgcgac
    66721 gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg gagcagcgtt
    66781 aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata tccctaaaaa
    66841 ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg ttactgcctt
    66901 ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg cggggatgag
    66961 tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct ggttcaaaca
    67021 aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt atctgctgat
    67081 cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg tatctggaat
    67141 cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa tctctgtgtt
    67201 tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt ttacactgaa
    67261 tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc cagtatgggg
    67321 agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct ctgtcatgct
    67381 ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg gcagtaaaaa
    67441 gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa agggaacagt
    67501 cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt tttaccagcg
    67561 gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca tagggatcat
    67621 tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga atgctttgat
    67681 gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg atcgtaatac
    67741 aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga tacgtgatct
    67801 gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac aagcactgat
    67861 tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc tttcttctaa
    67921 tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca caagccagat
    67981 tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa tcgttctcca
    68041 tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta gtgatgaaga
    68101 tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg aaagtttaga
    68161 taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc aacgcaaact
    68221 tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc agcaagatag
    68281 tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca ttgatgaata
    68341 cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga atatcaattt
    68401 gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat ttgcgtttcg
    68461 agcaaagtca aaaaaaacga gtccaataaa ataa
//
LOCUS       DAIGQM010000005        67363 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.005, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000005 DAIGQM010000000
VERSION     DAIGQM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.005"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(7..1269)
                     /locus_tag="NOA48_000266"
     CDS             complement(7..1269)
                     /locus_tag="NOA48_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788569.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(1262..2161)
                     /locus_tag="NOA48_000267"
     CDS             complement(1262..2161)
                     /locus_tag="NOA48_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788570.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOA48_000268"
     CDS             complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOA48_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCI0788571.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOA48_000269"
     CDS             complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOA48_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCI0788572.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(4667..7027)
                     /locus_tag="NOA48_000270"
     CDS             complement(4667..7027)
                     /locus_tag="NOA48_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCI0788573.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(7159..7689)
                     /locus_tag="NOA48_000271"
     CDS             complement(7159..7689)
                     /locus_tag="NOA48_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCI0788574.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELW"
     gene            complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOA48_000272"
     CDS             complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOA48_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCI0788575.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            8386..9303
                     /locus_tag="NOA48_000273"
     CDS             8386..9303
                     /locus_tag="NOA48_000273"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCI0788576.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(9559..10470)
                     /locus_tag="NOA48_000274"
     CDS             complement(9559..10470)
                     /locus_tag="NOA48_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0788577.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(10873..11451)
                     /locus_tag="NOA48_000275"
     CDS             complement(10873..11451)
                     /locus_tag="NOA48_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0788578.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(11471..12139)
                     /locus_tag="NOA48_000276"
     CDS             complement(11471..12139)
                     /locus_tag="NOA48_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788579.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(12154..13224)
                     /locus_tag="NOA48_000277"
     CDS             complement(12154..13224)
                     /locus_tag="NOA48_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0788580.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(13395..14759)
                     /locus_tag="NOA48_000278"
     CDS             complement(13395..14759)
                     /locus_tag="NOA48_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0788581.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLFEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(14756..16315)
                     /locus_tag="NOA48_000279"
     CDS             complement(14756..16315)
                     /locus_tag="NOA48_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788582.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(16371..18851)
                     /locus_tag="NOA48_000280"
                     /pseudo
     CDS             complement(16371..18851)
                     /locus_tag="NOA48_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18835..19170)
                     /locus_tag="NOA48_000281"
     CDS             complement(18835..19170)
                     /locus_tag="NOA48_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788583.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(19184..20218)
                     /locus_tag="NOA48_000282"
     CDS             complement(19184..20218)
                     /locus_tag="NOA48_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0788584.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(20308..20988)
                     /locus_tag="NOA48_000283"
     CDS             complement(20308..20988)
                     /locus_tag="NOA48_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0788585.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(21272..22375)
                     /locus_tag="NOA48_000284"
     CDS             complement(21272..22375)
                     /locus_tag="NOA48_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0788586.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(23004..23474)
                     /locus_tag="NOA48_000285"
     CDS             complement(23004..23474)
                     /locus_tag="NOA48_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCI0788587.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            23804..25444
                     /locus_tag="NOA48_000286"
     CDS             23804..25444
                     /locus_tag="NOA48_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCI0788588.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            25598..26920
                     /locus_tag="NOA48_000287"
     CDS             25598..26920
                     /locus_tag="NOA48_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCI0788589.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(26988..27422)
                     /locus_tag="NOA48_000288"
     CDS             complement(26988..27422)
                     /locus_tag="NOA48_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0788590.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(27487..28323)
                     /locus_tag="NOA48_000289"
     CDS             complement(27487..28323)
                     /locus_tag="NOA48_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI0788591.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(29065..29691)
                     /locus_tag="NOA48_000290"
     CDS             complement(29065..29691)
                     /locus_tag="NOA48_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788592.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(29986..30321)
                     /locus_tag="NOA48_000291"
     CDS             complement(29986..30321)
                     /locus_tag="NOA48_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI0788593.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(30308..30592)
                     /locus_tag="NOA48_000292"
     CDS             complement(30308..30592)
                     /locus_tag="NOA48_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HCI0788594.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(30648..32171)
                     /locus_tag="NOA48_000293"
     CDS             complement(30648..32171)
                     /locus_tag="NOA48_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0788595.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(32164..33339)
                     /locus_tag="NOA48_000294"
     CDS             complement(32164..33339)
                     /locus_tag="NOA48_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0788596.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(33343..33528)
                     /locus_tag="NOA48_000295"
     CDS             complement(33343..33528)
                     /locus_tag="NOA48_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788597.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(33494..35188)
                     /locus_tag="NOA48_000296"
     CDS             complement(33494..35188)
                     /locus_tag="NOA48_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI0788598.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(35185..35658)
                     /locus_tag="NOA48_000297"
     CDS             complement(35185..35658)
                     /locus_tag="NOA48_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HCI0788599.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(35727..35882)
                     /locus_tag="NOA48_000298"
     CDS             complement(35727..35882)
                     /locus_tag="NOA48_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HCI0788600.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(36016..36396)
                     /locus_tag="NOA48_000299"
     CDS             complement(36016..36396)
                     /locus_tag="NOA48_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI0788601.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(36400..36615)
                     /locus_tag="NOA48_000300"
     CDS             complement(36400..36615)
                     /locus_tag="NOA48_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788602.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(36618..37025)
                     /locus_tag="NOA48_000301"
     CDS             complement(36618..37025)
                     /locus_tag="NOA48_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HCI0788603.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(37291..38766)
                     /locus_tag="NOA48_000302"
     CDS             complement(37291..38766)
                     /locus_tag="NOA48_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HCI0788604.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGESTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(38756..39604)
                     /locus_tag="NOA48_000303"
     CDS             complement(38756..39604)
                     /locus_tag="NOA48_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HCI0788605.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(39641..40003)
                     /locus_tag="NOA48_000304"
     CDS             complement(39641..40003)
                     /locus_tag="NOA48_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788606.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(40004..40162)
                     /locus_tag="NOA48_000305"
     CDS             complement(40004..40162)
                     /locus_tag="NOA48_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788607.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(40303..40927)
                     /locus_tag="NOA48_000306"
                     /pseudo
     CDS             complement(40303..40927)
                     /locus_tag="NOA48_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(40924..41235)
                     /locus_tag="NOA48_000307"
     CDS             complement(40924..41235)
                     /locus_tag="NOA48_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788608.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(41279..41572)
                     /locus_tag="NOA48_000308"
     CDS             complement(41279..41572)
                     /locus_tag="NOA48_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788609.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            41766..42413
                     /locus_tag="NOA48_000309"
     CDS             41766..42413
                     /locus_tag="NOA48_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0788610.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            42474..43619
                     /locus_tag="NOA48_000310"
     CDS             42474..43619
                     /locus_tag="NOA48_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0788611.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(43700..44005)
                     /locus_tag="NOA48_000311"
     CDS             complement(43700..44005)
                     /locus_tag="NOA48_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCI0788612.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOA48_000312"
     CDS             complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOA48_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCI0788613.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(44458..44724)
                     /locus_tag="NOA48_000313"
     CDS             complement(44458..44724)
                     /locus_tag="NOA48_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCI0788614.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(44979..45704)
                     /locus_tag="NOA48_000314"
     CDS             complement(44979..45704)
                     /locus_tag="NOA48_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI0788615.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(46065..46135)
                     /locus_tag="NOA48_000315"
     tRNA            complement(46065..46135)
                     /locus_tag="NOA48_000315"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46101..46103),aa:Gly,seq:ccc)
     gene            46252..47004
                     /locus_tag="NOA48_000316"
     CDS             46252..47004
                     /locus_tag="NOA48_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0788616.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            47020..47499
                     /locus_tag="NOA48_000317"
     CDS             47020..47499
                     /locus_tag="NOA48_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0788617.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(47750..49330)
                     /locus_tag="NOA48_000318"
     CDS             complement(47750..49330)
                     /locus_tag="NOA48_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCI0788618.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(49323..50066)
                     /locus_tag="NOA48_000319"
     CDS             complement(49323..50066)
                     /locus_tag="NOA48_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788619.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(50242..51018)
                     /locus_tag="NOA48_000320"
     CDS             complement(50242..51018)
                     /locus_tag="NOA48_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788620.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(51266..52102)
                     /locus_tag="NOA48_000321"
     CDS             complement(51266..52102)
                     /locus_tag="NOA48_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCI0788621.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(52113..53042)
                     /locus_tag="NOA48_000322"
     CDS             complement(52113..53042)
                     /locus_tag="NOA48_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCI0788622.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            53234..53587
                     /locus_tag="NOA48_000323"
     CDS             53234..53587
                     /locus_tag="NOA48_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0788623.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(53661..54317)
                     /locus_tag="NOA48_000324"
     CDS             complement(53661..54317)
                     /locus_tag="NOA48_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0788624.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            54543..56477
                     /locus_tag="NOA48_000325"
     CDS             54543..56477
                     /locus_tag="NOA48_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0788625.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(56563..57786)
                     /locus_tag="NOA48_000326"
     CDS             complement(56563..57786)
                     /locus_tag="NOA48_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0788626.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(57780..59678)
                     /locus_tag="NOA48_000327"
     CDS             complement(57780..59678)
                     /locus_tag="NOA48_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCI0788627.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(59672..60790)
                     /locus_tag="NOA48_000328"
     CDS             complement(59672..60790)
                     /locus_tag="NOA48_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0788628.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(60873..61706)
                     /locus_tag="NOA48_000329"
     CDS             complement(60873..61706)
                     /locus_tag="NOA48_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0788629.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(61699..62616)
                     /locus_tag="NOA48_000330"
     CDS             complement(61699..62616)
                     /locus_tag="NOA48_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788630.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(62843..63967)
                     /locus_tag="NOA48_000331"
     CDS             complement(62843..63967)
                     /locus_tag="NOA48_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0788631.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            64150..65058
                     /locus_tag="NOA48_000332"
     CDS             64150..65058
                     /locus_tag="NOA48_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0788632.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            65199..66812
                     /locus_tag="NOA48_000333"
     CDS             65199..66812
                     /locus_tag="NOA48_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0788633.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKKPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        19981 a        13674 c        11306 g        22402 t
ORIGIN      
        1 tatattttat gctttttttc gttcatttct cataattgaa atcgattgtt tcaatgaact
       61 ccataatccg ccttcgctat acacgagtac attcgatttg tacatgtttg cagacaagat
      121 catcaataag aatgttacgg ctacaagtac caacaaggaa atcaatgctc cacccatacc
      181 gactgtctca tttgctaagc gaaccggcat aatatatgaa gataagaatg gaatatacga
      241 agtgatccga ataacgatat tgtttggatc tgaagctcct agtatcaatc caagcatata
      301 tccgcctaga gatagataag tcactggcaa aattgctttt gctgtatctt ctgctttgtt
      361 gaccaaagag ccacataaag ctgctaaaac agaaaaaatc aaaatgccaa agatcatgaa
      421 tagaagagaa taccacaaga atggtccaat caagttatcc aatgagatac cgtctaatat
      481 atttttgacc atttccatat ctttgaattg actgtatcct ataccaaaaa taataccgta
      541 taatgccatt tgcgttaatg caacaagtaa aacacctgtt agttttccgt aaaaatgctt
      601 ttgtgcagtc gtactggaca ggatcacttc catgatccgc gtgccttttt cagaagcgat
      661 ctcttgtgca atgatctgcg catacgtcaa aataataatg aacaagacaa tcgttgctac
      721 ataacttacg acatattgga ctgtcgagtt atcttctcca actgtcattt ttccttttga
      781 atcaaaattg actttttgtc gagtcaaact tgcttgttgg ctcaagctag ctacttcttc
      841 tggtgaaatg cctaattgac ttgctcgaag catcgattgc aagccagtca gttgttgttg
      901 tatcagtagt tgtgtacttt gtcctaatga attttcgcta taaagcatcc catttatctt
      961 atcattctca gttgagacta ctaaatacgc atcgattttt tcttccgaaa gctctttttg
     1021 tgctttttct tcagaatcaa ctgctttgaa ctcaaaatca tctgttttga cttggctcat
     1081 ttgctgactg atttgctcat tatcagccaa tacgccgatt ttattgacat cactattttg
     1141 ttgagcaaag tttcctgcta cataaatgat acccagcatg ataaaaggga ctaatatcat
     1201 gatcaagaaa gaaatcgact taacattttt taaatagaca tctttggtaa taatccaaaa
     1261 cttacgcatc gatttcacct gctttcaatt tgaaaatctc ttccaaagtt ggcggttgct
     1321 ggttaaacat aggaatgtag ccgaactgag tcgcacgagt aaagatttct ttcccagctt
     1381 caggatcttc taaggtaatc tctaacgtat tgtcttcatg aaggatcact tttttcacgc
     1441 cttcgatttc ttctacttcc tgttggctta aaccagattc caagaataac ttcgtacggc
     1501 caaatgattc acgaatctca tgtacttttc cattcaaaac catttttccg tttcgcaaca
     1561 tgatcaaatg atcgcagatt ttttctacat tatccatatt gtggctagaa aaaatgacac
     1621 atgaaccatg ttttttcaat tccaatattc catcttttag caattcagca tttaccggat
     1681 ctaacccgct gaatggctca tccaaaatga tcaatttagg ttcatggatt aacgtggcga
     1741 tcagctggac tttttgctga tttcctttag acaaagattt tactttatcc gtctttttcc
     1801 cttttacctg aaatttttcc atccaaaaat cgatttttgg ttcaatctct tttcttgatt
     1861 tccctctaag ttctgcaaaa taaagcagtt ggtcttgaat cgttactttc ggataaagtc
     1921 cccgttcctc cggaagataa ccgatgacat cataatcttt ctccccaaga tgatggccat
     1981 tccataacac ttctccttgg tcttgtgtca aaaaatccaa gatcaaacga aaagtcgttg
     2041 tcttcccagc cccgttttgg ccaattagcc ccatgatttt tccatcgggg atttggaaag
     2101 agacatgatc gacagctgtg tagttcccaa aagttttaac aagatccttg acttctaaca
     2161 tttcttcact ccttcttcaa gaaatcacat atatccttag acaccagacg taagcgattt
     2221 attatttacc aacaaaacgt aaacgctctt tttgttgtac ataaaatgat aggacacttt
     2281 actttctttg taaagtgccc tttcctcatt cctgatgtaa tttatcaaat acgttttgtg
     2341 cgacattttt cggcagtccg atttcttgta attcttctgt cgtggctgct gtgatatttt
     2401 tcaacgattt gaactcttta agcagcattt tttttcgttt tggtcctaac ccttcaattt
     2461 catctaatcg ggaagcaaaa ctgtttttac tgcgtagctg ccgatggaaa gtgattgcga
     2521 atcgatggac ttcatcttgg attcgctgga gtaagaaaaa ctctggtgaa tttcgctcaa
     2581 gcggtactac agccaaatct ataccgaata gcaactcatt tgttttatgt ttatcgtttt
     2641 ttgccatgcc agcaatagga atatcgattc ctaattgatt ttctaagaca tcttttgcca
     2701 catctacttg tccttttcct ccatcgatca agatcaaatc aggtaaaggc aacccttcgc
     2761 gaatcactcg tgaatatctg cgatagatga cttctctcat tgatgcataa tcatccggtc
     2821 cgttgactgt ttttatttta tatttccgat attcttttct tgccggtttt ccatcaatga
     2881 atacgaccat cgcagccaca ggattcgtcc ccatgatatt agagttatca aaagactcga
     2941 tacgtattgg ggtcgggata ttcatcgcgt ttcctaaacg ttcaactgct ccgatcgtcc
     3001 gttcctgttt tctggcaatc agatcaaacc gttcattcaa agcaactgag gcattcttat
     3061 tcgccaattc aactaatttt ttcttttctc ctcgttttgg ttgcagcact ttcgtagcta
     3121 acaaagcttc tacactgggc ttgtcgatcg tatcaggaat caagacttct ttaggaatga
     3181 aatgctcatt ttcctgataa aactgaccga ggtaagtcaa gaaatcttct tctgcttcgt
     3241 tatagaaagg aaacattgaa acatctcgtt caattagctt tccttgtctt acgaaaaaca
     3301 cttggacaca catccatcct ttgtcaatcg cataaccaaa tacatctcga tccagtaaat
     3361 cagtatttgt cattttttgg cgagtcatga ttgtctcaat ggcacggatc tggtctcggt
     3421 attctgcagc tttttcaaac tccatgtttt cagcagcttt ttccattttc tgatggatct
     3481 ctgactcgat tttttcgtgt cctccgttta aaaacttttt cacttcatca acgattttcg
     3541 tatagacttt cggatctacg tcgaaataat aaggacacag acattgtccc aaatgatagt
     3601 aaagacaagg ctccttcgtc tgactaggtt tgcattttct cagaggaaat aatcgatcga
     3661 ggatcttctt tgtctcattc gccgcaccga catcgggata tggtccaaaa tacagtgctt
     3721 tgtcttttag tactttacga gtaatcacca aacggggata tttttcattc gttatcttaa
     3781 ggaaaggata ggttttatca tcctttaaca taatgttgta tttaggatca tttttcttta
     3841 tcagattgat ctctaagagc aatgcttcga tattcgattc tgtaacgatg tattcaaagt
     3901 cttcgatttc actaacaagc cgttccgttt tcgtattatg gctgccagta aaatatgagc
     3961 ggacacgatt ttttaatatt ttggctttgc cgacataaat gatcgttcca tttttatctt
     4021 tcatcaagta acagccgggc tgatcaggaa gtaaagctaa tttgtttttg attcgttcgt
     4081 tcatctggta ctccccttca tattcaatta aagttattat agcatgtctg tcaaaaaaac
     4141 aatccagcct gacaacgtaa ttatactcaa aaaatattaa tttgaataac cttaactcaa
     4201 ccgcaaaaaa accgaggacg gaactggatt cagtcccacc ctcagcttat ttttgctgta
     4261 agtttttata aatattgatc gatcatttga cgtagttgtt cttttgaatg aacaccaaca
     4321 gctttttcta ctacttgacc atcttttttc aacattaatg ttggaatgct catgataccg
     4381 aattgttgag gagtttctgg attttcatcc acatccattt tagcaattct gaattcttct
     4441 tcatcatatt cttgttccaa ctgatccaaa atcggtgctt gcatacgaca tggaccacac
     4501 caagttgccc aaaaatcaat caatacaagt cctttatctg tttcttcatt aaatgtctta
     4561 tctgtaatta cttgtgacat atcaaagacc tccattttta aaatctatga ttagtatagc
     4621 atttctatac ttggatagcg aaccatctgc ttacctttag taagctttac ttaaatttaa
     4681 caattgtcgc accatttccg ccttggtttg ccggtgcaaa ctcaaagctt ttgacgctcc
     4741 gatggttttt aagataatca gtaattccct tgcgaagtgc gcctgttcct tttccgtgga
     4801 caatagtcac ttgaggataa ccagctagaa tggcagaatc caaatattga tctacctcac
     4861 ttagcgcttc ttcgtatcgt tttcctcgaa ggtccaattg attcggcacg tgactactag
     4921 attcagatcg tacagcatgg ataactcgtt gtgtcggctc tttttgagga gcaacaggcg
     4981 tcagctcgtc ttcggacaca ttcattttta atataccgat ttctacttgc cactgattcc
     5041 cgtttttacg taaaagcgtc cctctttggc cgtaagtcgt aaccaacact tcgtctcccg
     5101 gtttcaacgt tttttgttct ttcgccttct tcaatacttt atttttcttc aaagtttctt
     5161 cttgatgtag atttgctaat tgggtctttg catcgatcaa ctgatgctct ttcacatttc
     5221 cttgcccaat ctgctgttgc attttacgaa tatcagcaat gattttttct gctttttctt
     5281 ccgcctctga cacgacttcg tttgcttttt tctttgcttt ttccatttct ttttcacgtt
     5341 cttcaaagaa atagctgtaa gcttctttca aatcatcgtg aagttcttgt gcctcagaaa
     5401 caaaatgacg catttccaga tattcggtct ctgccatttt ccggcgattc tctaaatctg
     5461 tgatcatttc gtttaaatct tggctctcat cattcatcaa ctgcttcgct tcatcaataa
     5521 cttctgtatc aagacctaat cggctagaga tttcaaacgc attgcttcgt ccaggaacgc
     5581 caatcagcaa acgatacgtt ggacttagtg tatccacatc gaactccatg ctggcattaa
     5641 tcgtatttgc ccgattgtat ccataaactt tcaattcagg ataatgcgtt gttgccatca
     5701 cataagcaga ctttttacca agatcatcta agattgcgat tgctagagca gcaccttctt
     5761 gcggatctgt tcctgcaccg agctcgtcaa ataataccag acttttttca ttgacttttg
     5821 ataaaatatc tacagtgttc gtcatatgag aagaaaaggt cgatagactt tgctcaatcg
     5881 actgttcgtc tcctatatcc gcaaatactt cctcaaaaat accgatttga ctttcttcac
     5941 ctgcaggaat cggtaatcct gcttgcccca tcagttgtaa cagacctaaa gtcttcaacg
     6001 tgatcgtttt cccacctgtg ttaggtcctg taatgacgat ggcttgatag tcttttccga
     6061 ttgtgatgtc attagaaact actttttcct gatcgatcag tggatgtctt gcttgtttca
     6121 agacgacatg attgtcttca ctgattcccg gcacgatggc ttttacttct ttaccaaatc
     6181 gtgcttttgc attcatcaga tccattttac caatcacata agcattgtgg atgatttctt
     6241 gacgatgggg aacaagttca gcagaaagtt cacttaaaat acgttgaatc tcatttcgtt
     6301 cagcgatttg gtattgacgc aaacgattat tcaaatccac cacttgtttt ggttcaataa
     6361 ataaagtctg tcctgaagca ctttgatcgt ggactacacc gccaaataca ccgcggtatt
     6421 cttgtttgac tgggataacg tagcggtcat ttcgcatggt gatgatcgca tcacttaaat
     6481 actttgcatt tttcccacgg acgatcccat ctaactgttc acgaacagct tgttcacttc
     6541 gccgaatgtt ctgtcttatg ctctttaact caggagaagc gtcatcagtc acgcgtccgt
     6601 cttcatcgat tgcttccttt aaacggcggc tcaaaacagg gatcgtgact aactgatctg
     6661 cccacatata caaacgtgca aattcgattt cactgtcaga aagatcatca atgaaacgat
     6721 tcaattcgct tgtcgtagac aatactctgg aaacttgtgc aagctccact ccattcaagt
     6781 ctgctccgat ctcgatccgt ttcatatggg gacggatatt ttcaagttta ggtataggga
     6841 tcccgcctcg cagacgttgc actttcaatc catcctcagt ttcttgaagc cagtttgtga
     6901 tcgtttgttt ctcactcact ggtaccaatt ctgccagttc ttcttttcct tgtgcagtca
     6961 ctacaaattg tctgaccatc tgtttgactt tttcaaattc caatgtttca aggattcggt
     7021 tattcatttt atcaccttat ctttcactat gaaaaaagag ctgtgccgga catacgctac
     7081 gcagccttct taaataaact actctgtaca aaaaacgaaa tattttccag cactattttc
     7141 cttaattcaa aatattcgtt accaaagctc atacatcttg ttggtaagaa atggcgttct
     7201 ctcaacgata aaacgagcga aactatgctc gccgaattga ttttggacca catctaatgg
     7261 aacaaaggca agtaactgca aaatcaaaaa tatagtaacg taagccatga ttagtgacag
     7321 gatgcctcct gcaatccagt ctacctgtct caagatcggc acatacgtca atccatggac
     7381 aaaaaccccc acaaatcggg taagcagcca gccaattagc aaaataatca gaaaagcagt
     7441 tcctgcataa aaagcttcat ctaggtgaaa agcaaatacc tgatcaaaaa atgctaactt
     7501 tgatgttggg gtgacagctg ggtatggaat gtataattcc aaatgacttg ctaatggttt
     7561 gtaaaaatgc tgggcagcaa taaatgacaa tacatatcca atcgcgaata tgatttgcaa
     7621 agcaaacccg cgacgtgctc cagaaaaaaa cgcaattagc aataaaaata aaatcagcaa
     7681 actcagcatg ctacgttcct ttctcttcta acttttttaa atttttctta ttttgataaa
     7741 aggatcttaa ttagaagatt tttgtttaat ttgtcctttt cgtttctcgt ttaaaatctg
     7801 ttgtgcttcc acatgatttt taatggtatg atctgcttga ccattttctt tcaatacttc
     7861 ccgagcttcg ttctcgattg cttcaatgcg tttcacacga ttttcaagct ctgtaaattt
     7921 gatcattttt ttctttaatt ctgctgtttc ttcttccagc tccaagattc tttcttgttt
     7981 cttcaattga tccgaaagcg cattgacagc catcaagatt gctgcttgtt cattatccat
     8041 ttgtggtgat aattgtttca attctgctaa ctgttcattg atcagcttcg ttacgatatc
     8101 catatgatgc ttggtttccc gtccgataat agtatatgtt tggttggcaa tcactgcttt
     8161 gtagcgtgtt ttttcgtgcg ccatacgaat catttcctcc tatttgatga aagttttatt
     8221 tagtgtacca tgaagttggt tctttcaccg ttctccacaa atatttttca catacttaac
     8281 tattatatga taaactttaa aaaaatgcta tgtctcgcaa tctcttagaa aacgaaaagt
     8341 cgtgagttgc ggtatagttt tatgtataaa aacgaggaga attttatgag caacgtcatt
     8401 atcaaagcaa caaacgacca acttagtcaa atgaaagcat actatcgctc ttatttgtta
     8461 aataaacaga ttccttatac tagctttgct gcaaaaaaag acgggacgac cattaccgct
     8521 tatacatccg gaaaagtgat gtttcaaggt acgaatgcag caatagaagc tgataaatgg
     8581 ggggaggcac aggataaaca agccaagcca gcaaaaacag cctcttcttt gccaaaaaat
     8641 atcagtcaat tatccgtttt aggtagtgat gaggtcggaa atggcagcta ttttggtccg
     8701 ctaacagtat gtgctgctta tgtgaaacgt gatcagcttg cagaattacg taaacttggt
     8761 gttagagatt caaaagagtt aaaagatagc caaatcatcc agcttgctga catcttaaaa
     8821 aaaaccatcc cctataaact gcttgtctta tctccagaaa aatacaatga gatccaacca
     8881 aaatacaatg ccgttcggat gaaagtcgct ttgcacaatc aagcgatcca tttgctgcta
     8941 aaaaaaatcg agccagaaaa accagaagcg attttgatcg atcagtttac gccggaagca
     9001 aattttaaaa aatatgcgcg tttagaaaaa aatcaattac aagaaaaact gtacttcgtt
     9061 actaaaggag aacaatatca tttagctgtt gctgctgctt ctatcatcag tcgtgccagc
     9121 tttttggaag agttacacaa agcatcagct gaagctggaa tcacccttcc atcaggagct
     9181 ggaacgaaat ctgaccaagt agcggcaaaa ctattggaga aaggcggcat gcctatgctt
     9241 gaaaaatatg ccaaacttca ttttgccaat acagaaaaag ctttgaagct gctaaaaaaa
     9301 taatggaact gtgacaaaag tcatgtcaca gtcccttgtt ccgaataaac ggtgttctca
     9361 tgccaactcc tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa
     9421 ttgctccttg tgacgcggag ttaaacggca ggctcacaac ctcttcctta aacggtgttc
     9481 aaaagcttgc atctgcgata ataagcccgg ccaaacgaaa aatatgagga gctatttttg
     9541 tttggctggg cttatttatt actgaaaata agtggtcaat gcttgtgtca aacttgcagc
     9601 aatctgctgc tgataactgt ctgttactaa ttcctttaaa tcactatcat tattcatata
     9661 acccatctcg attaaaatag aaggttgaag attttctcga agaacttgat agttcccagt
     9721 ggagattcct cttgaatcca gaggcagatc agtgaaggag tcagcaattg tctgtgctaa
     9781 tgtttcctct tgtccatagt aataatatgt cgtgattcca gttgcttcat tcgcatattc
     9841 cgtagagtct gcgtgtaaac tgataaagac atctgccttt ttttcttcac tgtagtcgca
     9901 tatatctcca agctgtacta attcatctgt agtatgggtc aaataaaccg ttgctccagc
     9961 atcctctagc gcctttttta cttttatggc tgtacttaat gttatatctt tttcttctgt
    10021 ttgttcatca ttgcttaatg ccccagtatc atttccgcca tgcccaggat ctaatacaat
    10081 cactgcatca gatagctctt ccggttttgt ttgtatattc tttgtgactt tggttccatc
    10141 ttcgagggct aaatatccag tatagccatc atttgtcttg atctgataag cattttttgt
    10201 ttcagaaaga aactccgcca gctctccgcc gtttatagtt gcaagtgggg tagttagcga
    10261 gtcatctgta tatagtgtac ggtcattttt tccgattttg attaatgtct cttgttctgt
    10321 atcatcaaat gattcctttg tctttgtaac cgtactgttc gtactgctga ccgtttgtcc
    10381 aactatcttt ttttgaccaa aaacatctat ttgaaaacag ataataatga taatgattgc
    10441 aaatacaaaa gctccaatta tttttttcat tcttgactct cacctcgtag atccagacta
    10501 agggtcaaaa cttaaaatca gcttaagtac gcaaaaaagg ggctgtaaaa gatataaccg
    10561 tagaaaataa cattactgct aaaatgattt ttttcatttt tggcatatcc tgaaatctcc
    10621 ttttgactat tcgtggtgat tcatctaccc aataaatagt ttccttcatt ctacaaacaa
    10681 ttaatttctt cgttattaaa ttaaaacact tcctggaaca ccgacataat aaataaaaat
    10741 ataccctgat aatcatgaga gaataacaaa tttgtattta tgaaaaacta cctatataaa
    10801 aaaaacaaga tataacgatc ttcgtcatat cttgcttctt cacctaacta tttttctccc
    10861 tatataacag ctttacgctt ctcctaatac accattcaaa tataaatcga tcaattgcgc
    10921 cacatttagc ggttcttcca caggtctttt cgaccgagtg atgtaaggtg ctaacactaa
    10981 gaaaaaatgc cttgctgcga tttcttttga aatcccattt cttagcacag attggtttgc
    11041 tgaaaagatt tcttcaaaag gttcacgata atttttcttc catagaaaga aaagatgatc
    11101 tcttgtttcc tttgaaagat tgctttcaag atcgtgaagc atcagaaaca aatcgaccag
    11161 atgtgtctca atcaaaaact gcgccatttt tgtcaaggtt acttgaaatc ccgtttcgct
    11221 tgtttgaacg atttctctca aagcttttcc aacatctttt aagtggtttt ctaaaactgc
    11281 cgtatatagt ttttctttat caccgaaata atgatagaga ttgggttggg tgatcccaac
    11341 tttttgtgcg atctctcttg ttgaagtgcc gagatatccc ttggacataa acaagtcagt
    11401 cgcttctttc aaaatttttt gctgtgtatc tttgttgtat cgatggacca tttttccacc
    11461 tgctttttgg ttattctttt tctttcaata caccatcttc catcataaat attctatcgc
    11521 atttgtcaat cagccgtgta tcgtgagtaa ccatgatcgt tgctttattt ttgtcttttg
    11581 attcttttgc caagatatcg actacttctc gtgccttttc tgaatccaaa ctagcagttg
    11641 gttcatctgc tagaataatg gacggatcat tgtacaatgc acgagcgatt gcgacccttt
    11701 gccgttctcc accagatagt tcttctggat acttgttgat caacttatcc acgccaagct
    11761 gctcaaataa ttcttttgct tctttttgac gatgttcatg tttgatctta tctactaata
    11821 ataactgctt ttttactgtc agaaaaggaa ccagattgga agcttgcaaa ataaagccaa
    11881 tttctttaaa acgtagttta acgcgttcac tttctttttg attactgaat tcttgatcat
    11941 tgataaatac agagccactg ctaggcgtct gcaatccgcc tgccaaagtc aaaaaagtac
    12001 ttttacctga accagaagga ccgatgattg caacaaattc ccctttatcg atactcatgg
    12061 ttgtttcttt caatgcttta actacttggt cgccatcttg gaaacttttt tctacttctt
    12121 taaattctat tgctttcatg ctcttcctcc ttcttatcca attgccttca acggatcgat
    12181 ttttacgatt gtccgaacag aaaatagtgc gcctaacaca gctactacca gcatcaacaa
    12241 gctaatgacg ccaaaaaaca gccaattgct ttggaatgga accgcatcag gtagaacaag
    12301 ggatgttccc actgttccta atagaccaag aagaatacca acaaatgata aaatgaatgt
    12361 ttgtgccact acagaacgcg caataaatcc tcctgtgatc ccttgtgctt tcattacacc
    12421 aaagatatta atcttttgca tcgtcagtac ataaatgaaa atcccgatca caatagccgc
    12481 aataacgatc aaaaatccga tcataaatcc aaaagtcaat acttgcgcat tatatccagg
    12541 taattcattg atgaatttag aaattttgat ctgttctaaa tcttcaggta aattactgat
    12601 tttacctctg acaactattg cgttaatccg tgcattttca cttgtatctt ctttttcgaa
    12661 gcggatctct tggtaagcat tgatggttgt atagagaact ggtgagacat tgaatttggc
    12721 atgatccgta aagccagtta gtttaaacgt cttgtcacta ccagataact taactgtatc
    12781 tcctacggct agaccatatt cttctttcaa actaatatcg cctactgcct catcatcgtt
    12841 atcaaaagct tttccttcaa caagattggg catgatgaat tgatttttat cgataccgaa
    12901 gaagctaaca ttgatttttc cttcttctgt actgtcttta ctagtcacga ctccaggtgt
    12961 ctgggcaaga tacgccactt tcccaccttc gacttcttct gctatcttct tagtaatcat
    13021 ggacatccct agatttgaat ttgcatcttt cgaaagcaca atcgaatctg cctcccactt
    13081 gtcgactgct gttcgattat cttgagctaa gccataagct aacccagtca aaaaaaatac
    13141 caggtaggcg atcaaaaaca tcacccctgc aactaacgca taacgtaact ttgaatgcat
    13201 aatttcattt aatgctaaaa acatttaact cctcctcctg aaataatcat tttatacaac
    13261 aattttatca cttgataaat ttttggcgaa tattatgctc aaaaaattct tccgctattt
    13321 cattatatga attttttatt ctcgattgat taatatttat tatatcccca cacaataaaa
    13381 gaccgtgata tttctcacag tcttttatct actctattgc tatttgctct cttagctagt
    13441 actttaaaag ctaactcatt gaggtagtga aaacgagagg tgtgttcaaa cagaaatcca
    13501 aaatcctcaa ctgctagctg tggaatcgta gttttgtgtt tcacgatatc cgcaagcagg
    13561 ttcaaatctg ataataagaa ttcttggctt atcagctgtc cgccaattat ttctaatgta
    13621 tccggatggt agatcagctt tgcatttact gttttgtttt cttcatcgta ttgtggaaat
    13681 agatcaaatt ctcctgaaca cgaaccggta ttttgttcca agaatggcgc ttcatcttct
    13741 gtcagcccta cagttcctaa aaagtagtct ataatgactg ctgctgttat cttttgtctg
    13801 aggtcgtaag cggttggctg accactcaaa gttagcgcta ctgctcttgc catatgtaca
    13861 gctcgagtaa ctaaaggtaa aaagagatgc cgtttatttt tgtcaaaact gactgggacg
    13921 atatctccaa tcgcatagat gtccggatca cttgtctgca gatattcatt gactatcaca
    13981 gtctcatcct catacaaagc cactttttct tttaacaatg tcgtattagg acgagtttgg
    14041 gcagaaaaaa tgaccatatc tgcctttatt gcttgagata gaagttgtac ggatactact
    14101 ttctcttctg attttttcca atcgatcaag aattcatttg gataaaaatt gatttgctta
    14161 gtttgcagct gattttgaaa actgttgatc atatccttat cgaaatatct tgataaaaca
    14221 ttcggcatat aatcaactag atgaataatg tatcctttat ttctcaaagc atctgctaat
    14281 tccaatccaa tataaccagc accgaagatc actacttctt ttgcttcttt taaagcggca
    14341 agtacttgct tagattgcac tagattttta taggtgtaga cattttcagc ttcaatttgt
    14401 ttatacaagg tgacaggaga ggaacctgtt gctacgatta atttatcata ggttatggtc
    14461 tcgttttttc cttctttgga tgcgaggatg agctgatgtt tgtctggatc aagttcagtt
    14521 actctccatt cggtgatcag ttttgcccca ctttcttgaa gagtccgcat gttatgggca
    14581 acttcagcta aactacgtat ctttcctttt aaataaaggt tgattccatt tgaaacatag
    14641 cctagtccat ctttatgatc ttcatcgatc agtaaaactt ctgctttcgg ttgaagtttt
    14701 cttagattta gggcagctgt gatgcctgca tgggaagcac caatgatcac gattttcatg
    14761 ttttattcat ccttaaattc aatttttcta aataacattc ttttaaaaat tggttcaaat
    14821 aggggaaatc ataattatat tcgttgctag tgaatacaaa aactttagcg gacttctgtg
    14881 acgggtactc tttcaattgg ctagtcaaaa tgatatcata ctgcttttct ttctcgtatt
    14941 cgactaaatc atatttgatc gtattcagca attgttcctg gatgatttct ttcacgatat
    15001 ccgccattag cctttcataa ggaagatcat aagcaatttg cagacgtaat tctaactgct
    15061 tgatcagcgt ccgcaaaata gatgcatagc gagcaaataa ttcaaagcgg gcattttcct
    15121 cgtctacttc agtaaaatca acaatagcaa atgtttgtct gaccaatctt tcacataaaa
    15181 ccaggaattg tttatcttct acttcagtta accgctgttt taatccttct tggccaaaaa
    15241 tattcatcca tcctctaaaa taggcaaaat gagcgtgatt ttgcatcact gtcaacgcaa
    15301 tcttttgcga aatctcttct ggaaaaacat aaaaagagaa atattcttct atcgattgtt
    15361 taaacgttcg attcaattga gctactacgt cgtctttgta tttttcgctt atcaaaaact
    15421 cctggacatg cgagttatgt gtatctaatg taaagttact gatcatgaaa agataaaaaa
    15481 ccaacgtttc attttgattc caaggaaagg catattgaaa gaagtaacgg gtcaaaaatg
    15541 tatggaggtc caataaaaat tgtgtcgttt gaaacaatcc aacaggaaga ttgctataat
    15601 ctggtttgga ttttttcgta cagcgcattc gcttcttcat aatggaaagc catatttcaa
    15661 atttcaatcg tccttcttct gtaatagtaa aactaaactc tttttgcagc agatctaaaa
    15721 aagtgtttcc tgataaatca ctgtattctt ttttgttttc aagataagga cgtccaaacc
    15781 aaaataattg gaaataaaaa taacaaattt gactttctgg accggtcagc cgcccgcttt
    15841 ttattttcag atgaaactca tttaaagaat catttaattc cttcactctg cgagacaaag
    15901 tagccgaact gatattaagt tccatgacaa gtttctgccg atcaaatgag ccattttcca
    15961 acagataaag aagtatctga tattttgtag aatagcgcaa gtagcaatga taataaacat
    16021 cgactgctgc tatatttcca tgtctgatta ataaaatatt cccttcttgg ataacaattt
    16081 ccaattgttt gatattttcc aagttagctt gtaaataaaa cagatcttct ttcaaggtag
    16141 cccgatcaac tgataagcgg gtaagtacgt tattaacgga aatctctcct ttttcctcta
    16201 ataaaagttg gaaaagtttg atttgccgtt gttcattttt ttcaagcaaa ctgaaaagtt
    16261 ccaagtccac tcctccaagc atttctgatt ttaacagcag aagtttcctt ctcatccttg
    16321 aaaaagagga tctgtgacag ttatcacaga tccatacaaa ttctaatcac ttagctggtt
    16381 ggcccagctg tcagttccca tgtgaccatg ccttgatacg ttgcgccagg ttgagcattc
    16441 gtactgctat ttacctctaa gagtaaacca tcggtatcgg gaaagtcaac gagaacctct
    16501 cctttagctg ttccatcact ctcataaatc aacgtgtttt gaccttgctg aatcaattgt
    16561 tttgatccag aatgattgaa gtataatttt gttccgctta attcttgacc ttgatcattc
    16621 ttaaataaag aagtcaatgt ccctgtcagt tgccaaggag acgtgcttgg aagccgagta
    16681 tcccgcacat caaaagaaaa atcgcctttt gcttcataat aacttgtctt caacggtttg
    16741 gggagatcgt taccaaatgt aaaatcatct ggtacattaa ctaatgttaa ttcttgtttg
    16801 gggacaagaa ttgttttagc agatgtttgg acaactgggt taggaagctt agcaccatct
    16861 gctaatgtaa tattgctgga aagtacagct gcctttgtca gtatgctgac ggattgtaca
    16921 gaagtatcta cagtatttaa ttgatagttg taagtaagat gaatggtatc tcctattttg
    16981 ctcaatagat ctgctgggac agaaactcct tgttgaatgc cggtatctgc gatagttgta
    17041 ccatttaatt ttaaggaacc attgatataa gtagtatttt caggaagtga gatcgtgatt
    17101 tttttgtcgg ttatcgcatc cccagatttt gttaacgtga atgtcacatt ttcttgaatc
    17161 gtatctcctg atagagcaga caggggatct cctgtctcag gttgtctgct aaggtttttt
    17221 agctgactat ctgcactcac agatggaaaa ttagccactg ttatttgagg aagagtggtg
    17281 attccagctt gttcagactg ccatttgtac gcaaaagacg gatacatgtt agtaagtaca
    17341 tcgtccacca agcgataatc aaaataatat tgccctgaag ccaatgcagg tagtgtagaa
    17401 gtagctgtat ttacaccccc gttatttgat tggatcgttt ggaaaagttg atctgtccat
    17461 cctgtcgcta atttttaggt tcctttcgaa taaagcctgt aatggatcga accctttttt
    17521 agttcagttg ctgaccaatt ggccgtgact tggtacgatg cagaagaaag gagctttccc
    17581 cactgactat cggctgttaa gtttgttggt aaaaccgttc cgtctagctt gtactgctcc
    17641 aataccttta aagcaacagg agaaagcaat ccgccttgcg catctttccc actgtacacg
    17701 atattggctg tctgattcaa tccacttgtg cttgctggag tatgagtcag tattgctcct
    17761 tgtgtaacgt tttttcctgt aaaatagttg actacgcgat caaagcgact aaatggcaac
    17821 tgatcaaaac gtccttcagt cagccccatc gtcaatgtcc gactattggt agagcctgga
    17881 aggttctggt tatttccatc cacgtattct gtggtatcag caaatgtatt atattttcct
    17941 gttgaatcac ttgttgagat gtaactattc cacgtattta tctctgcact tgcagaaaat
    18001 gcatatgctc ctggattcaa gtttccgcca gttaatttag gataaaatct acctgcagct
    18061 ggagctaaaa tcgaattgaa catacgatct tggataatat tattcgaatc ataaaaatca
    18121 acagaaaaaa cggccttttt agacatagaa ggttgtaatt tacccttggt caaaattttg
    18181 tttggactcg tatcatattt atctccgttt tctgtcatct tcgcgacatt agctgtaaca
    18241 tcaaattgaa gcgggatatc gtccacgttg aattcgcctc gcgtaataat agcaataata
    18301 tctgccaata gagtatttgt atcccacgac cccatcccaa aacgcaaggt atggcttcct
    18361 gctgataata aactaccgct agtaaccttg atgggggcac cggcaatata caagtaggcg
    18421 ttgttccagt caattgcttt taatacatca ctgcttgata catgttccgg caaattgatg
    18481 atcgccacaa atgcaaatcc ttgtgcagtg atattcacca aatcaagtac atttgttagt
    18541 ttcacatggc tttcccaatg aaaacggacc gtgccacctt tccaaggatc atttgaacca
    18601 tcgttcaaat aagtagcagt caatttaggc aattggttag ccccagttag ttggacaagc
    18661 ttcccgccat tgactgcact acgtccacca tttggaggta cgatattttc atacgtgtat
    18721 ggatcataag aaatggcagg aggcgttgct ccaacagctt ctgccgaagg tgaaaagata
    18781 aatatactta aaacaaaaag cgaagtaaaa aagaaggagc gaaaaaatga aaatttattt
    18841 tgtagcaaca tgttcatcct ccttttcctt tcttctccat aacaacaacc acgcaagaag
    18901 ccataattct ataccaatga tcaaataaag aaaacggatc ttttcttcat tcgtctccgg
    18961 gaatacgcca tgttgattag attctttata aatcggtagc tgtgtctgct gttttgatgc
    19021 gccattgact gaaccacttg gatgcggaac tggacttaga tcataaaatg taatcgtacc
    19081 tgaacttttg gtatctgctt ggactggctc ttgccagctg aagaacagca aacttgcaat
    19141 aatccctccc aataagatcg atgttttcaa cgaaatcacc tcatcatgtt gtttctcctt
    19201 ttttcttttt cttgtggacc cacaaaaaca gcaaaatcaa ccataacact agaactgcag
    19261 caaccaatcc tgcataaagc catgggaaag attgttcttg tactgcaaaa acggaatttt
    19321 catttacttt ttgtgctttt tcttttttga tcgtaaagtt ttgtgtaaat cgccattcat
    19381 tactgtcgcc tgattttgct atgatttctg cgcggtaatc gccggctttt gctttatcac
    19441 cagctaaatc aagattcaag tgaaaattcg aatttggtgc aactaaaaat tcattagacg
    19501 tattttcaat ataaagctga ttttcataaa agatcttgct cgtaaatatc aaattgctga
    19561 taatcctagg ctgaggattt tggaaacgaa gctgaacagt tggctttgcg ttgacctcgt
    19621 ccaaatctcc tgataaaagt ttcagatccg gttctatcgt ctcttgactt tcttgtaaaa
    19681 cgactgcgag attataagca atacgatttt tgatttgtgc tccttctgta gcattttctg
    19741 tttcagcttc ttctttaggt gaaacatgaa tacccgctaa tacacgtccc ttaaagcttt
    19801 ttgctgggat tttcacttct ataggtatag ttgtttctgc atgtgctgat acattgattt
    19861 cctttttcgc aatgagcaaa acgtcacgga catcaaacgg caatgtctca tctaacgttg
    19921 ggtttttttg actataatcg atcgttccac catcactcgt taccgccgga ttgacagaga
    19981 cctcaaatgt tcgttcttca tctgaagaat tgctgataat tacttctagt gtctgatttt
    20041 gttccggtgc cactaataaa tcaaaataac cgattgcttt atctatttgg ttctctggaa
    20101 ataccggttt gattccaaag tctcctgctg aatcctttgc ttggctgatt gacggaaaaa
    20161 tgaaaaatag acttaaaata gaaaaaaacg aaacaaacag tcgtttactt tgattcattg
    20221 tccaccacat cctttcaaca acaactgcgg taaaaaatcc ttcacctata gtattttcac
    20281 cgcagtttgt tgaatttatt tcatactcta tgctactggg ccagccacga ggttccaagt
    20341 caaatcagcc gtgaatgttc cagctgctgc tttcggcact ttcagtgtga tatttgctgg
    20401 atcataaaca gaaagccatg ttcccagacc ttgatctttt gctgctgtaa atattggtgt
    20461 cgctgcactt gctttactca acccagttac agtttgacta gttggtccag tggattcgtt
    20521 atctgacgta cttttaacag tggatgttcc aaaatctaat tcagcgcctt gcaaaacttg
    20581 tgaaccgttt acaaaatctg aaaccgaaac tgtcacgttc cacccttgtg cttggccatc
    20641 tgcacctaca cctcgacgat ctgatacttg gagataaggt gtatcgtttt ttgaagcgtc
    20701 tacttgatac gtttttgttc cgctttcaat ctcgtgtgta ccaaatggca attcaggaac
    20761 tacatccaat gttaaagaac ctgtctggcc agttgctgga ttttccggat ctgctggctc
    20821 tactggtttt gaaggatcag tagggttaag aggctcaacg gtatttgttg gttcagtaaa
    20881 ggtaatatct ccttttgaag tcgcttgacc ctcagcaaaa gctggtgttg ccaagccgcc
    20941 tagaagaagt gttgaaagta ataatgtccc aatcatgttc tttttcataa taaatcactc
    21001 ctttttctta gtgacctaag tatagtagag acagtatgca aaaaatcctc atgaattcat
    21061 ccgcttactt gaaattatga ccctttttgt ataaaagaga aaaaaacaat aaaatcgttt
    21121 acatgaatat tcttcctttt ttattaagta tgaaaaaata tttcaatttt attttttcgt
    21181 ttcaaattat tctattagtg acatccttga actataaaaa taggagtacg gcatcatctg
    21241 ccgcactcct atttttttcg tcatttattt cttaaataaa acgattctca cgcaatttta
    21301 tttttttgat atcttctact gtttgtgttc cagctaattg catgaccatt tccaattctg
    21361 ttttaaagaa atcaaacact tgatggactc ctgtacttcc tcctaaagac aatccataaa
    21421 taacgggtct gccaatagca acaagatcgg cacctgatgc gattgctttg aaaacatgtt
    21481 gtccacgtcg tacaccgctg tcaaacacga ttggtacacg tttatctact gcttctgcca
    21541 catattgcaa cgaatcaaac gcagcaggcc ccccatctaa ttgacggcca ccatggttag
    21601 atacccaaat tccaccagca ccagattcta atgatcgata gacatcttct tctgattgaa
    21661 cacctttcac gtagactggc aaatcagaat gagcagcgat aaattctaca tcttttggac
    21721 taagtttttg tttggaagat ttatatacag catccatcgt ttggcctact cctgattgat
    21781 aagcctgaac gatcggcatt ggcagcggga aggtaaaccc gtttctgcgg tctgtttcac
    21841 ggtttccgcc aactgttgca tccgctgtca atacgattgc ttttgctcca ttacgcttgg
    21901 ccacttcaag aatatccaaa ttgattccat tatctttgct catataaaat tgaaaccatt
    21961 gcggtgcttt ctccccgcct gcttctctta tctcttctaa agtacaagaa gcgtaagaac
    22021 ttgctgtata gatcgtccca aaatctgcta caccttttgc agaagctttc tccgccttca
    22081 catgagctaa tccatgagca gcaactggtg ccatgatgat tggtgcagtc agcatttctt
    22141 cgtcaaaatg tgtagttgta tcgggtaatt ctacatctct taatacatga ggaataatca
    22201 aacgatgatt gaatgcccgt tcattttctt gataagtaaa taagtcgcca gcaccactgc
    22261 tgatgtaacc ataaccacca gctggaatca cttgtgaagc cgcgatttct aaatcttcca
    22321 tattgataaa atctactatt ccttcatttg tacctgcttg atatgttttt tccatctcaa
    22381 tgccttctct ctataaaatt tgaatgatga acaatatgat agcgtttaca ctttttatat
    22441 tactcttcga cattgataca ggcaaataat ctgtttacat ttcagccatt ccagatgtca
    22501 ctactctgga agaaatgatt gtaataaaaa tagataaaaa accgatggga ctttgacaaa
    22561 agtagtgtca aagtcccttt ttttgaataa acggtgttca aaagccattt tctcggtatt
    22621 aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
    22681 aactaagcga ctttttcaca acctctcgat aaaacggtgt tcaatcagct gaccctcggt
    22741 attagctcaa aaaatggcaa aatatgagga actattttgc catttgtctc tctaatactc
    22801 aggtcagaac gttgacttca cagtctcttc cttaaacggt gttcaaaaac ttgcatctgc
    22861 ggtaataagc ccaaccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt
    22921 acttgatgca gggcaggttt ttcacgacct ctgattcacg gtgtttcttt ttcatcaaca
    22981 tttttacgaa atactgtgga agactattga aataagtgtg gattgtttct ttgtgtttca
    23041 atcgtttctt gccattcttc atttaatttt ggattaccgt tttcttcctt gaactcataa
    23101 ggtcctaatt caaaaatccc agacagtatt tgattcacga tttcatatag ttcagtgtga
    23161 tcagacacat gattcttgaa gatcatctca ttatcaccac gtttgaacct cacattcggg
    23221 ctctcatgat gaacctctat gcatttttct ccttttttta actgacggac ttctgaaaac
    23281 atctcataaa tatcttctcc agtaaaacct tcagcaagcg ccagactgtc cacaagaccg
    23341 cctactgtca gttcagagat tattgcttga ttggaatcta attttaatgt atagcttgtc
    23401 gcttctacta cgccacatgc attgcaaccg ccttctgata gttcgctttt tctaatcaat
    23461 tgaacttctt tcattttctc ttcctcctct taattttcta cttatgtatt tttatcacct
    23521 gacataggtg actcctatca acgctatcat gtgctttttt cctcagaaat cctatttatc
    23581 cattccatct atcccttatt cttctacttt tctttctcta gcatataaga gatacgcata
    23641 gtattcaagc aaggattgtc gatataaaaa gaacaaatac tgctattttg atttcttttg
    23701 gctatattac atataaataa aatttatcat acctgctctt tttgactata tcatcatctg
    23761 acttctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta cagggttaaa
    23821 cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag aacgggcaaa
    23881 atatggaatc actggtatgc ttccaagtac tgtccaaaca ctggaacaac aatctgttca
    23941 agcttatggt caatacttaa gcaaacaaac agatttggaa aaacgtatct tcttaatgaa
    24001 tctattcaat acgaatcgga cattgtttta taaattgatg ggcgaacatt tagttgaatt
    24061 catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca acgaaatttt
    24121 cttgaaaccg caagatgctg catttctttc aatcgacgaa ccagaaaaca tcaaagcaag
    24181 tttgaagaac gcggcagatg gacgagacat tcgtttgatt gttgtgactg atgcagaagg
    24241 aatcttaggt atgggcgact ggggtgtgaa cggtgttgac atcgctatcg gcaaattgat
    24301 ggtctatact gctgctgctg gtattaatcc agcacaagtt ttgcctgtat cgatcgacgc
    24361 tggtactaat aatgaagaat tattgaataa tcccttatac ttaggcaatc gtcatgctcg
    24421 tgtagaaggc gaaacttact atgaattcat cgatcaattc gttcaatcag ctaccgaatt
    24481 attcccagaa ttgttattgc attgggaaga ttttggacga ggaaatgctg cagcgatctt
    24541 agaaaaatac gaagatcaaa tcactacttt caacgacgat atccaaggta caggaattgt
    24601 tgtcctagca ggtgtattag gcggattgaa tatatccggt gaacaattga aagatcaaat
    24661 aattttgaca tttggtgctg gtactgctgg tgtgggtatc gcaaacatcc ttttagatga
    24721 gatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc aagtagataa
    24781 acaaggttta ttgtttgaag atacagaagg attgactcct ggtcaaatcc cattcgctcg
    24841 caaacgctca gatttcacta atgctgatga attgacaaac ttagaagcag ttgtaaaagc
    24901 gatccatccg acaatcatga ttggtacttc tacccaacct ggagcattca ctgaagaaat
    24961 cgtgaaagaa atggctgctc atacaccacg tccgatcatc atgcctttgt ctaatccaac
    25021 aaaattggca gaagcaaaag caaaagattt aatagaatgg acggacggaa aagcattagt
    25081 tggaacaggt atccctgctg ctgatgttga atataatggt gtaacttacc aaatcggtca
    25141 agcaaataat gctttgatgt acccaggttt aggacttggt ttgattgctt caacagctac
    25201 acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa tcgttgatgt
    25261 aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat tttctcaaac
    25321 gattgctgaa actgtcgcaa aatcagttgt cgcacaaaac ttgaatcgtg aagaaatcac
    25381 ggatatcaaa gaagcagttg aatctgctaa atgggttcct gaatataaat ctttagaaga
    25441 ttaagatcgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa aaagaaaaaa
    25501 gcgactgcgg caaaacagcg gccagccaac tcctgctctt ttgtcgcttt tctttggctt
    25561 ttttcatatg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa caacaactgc
    25621 aactgcagtt gaggaaaaga aaaaagaagg tttttggtcc acaaaaatca ccggcgtaag
    25681 tttgccactt tatttgatca tggtccttgt cctgatcatt gcaatggctt tagggaaatt
    25741 accgacgaat atgattggac caatcgcagt tttggttatt ttcggtaatt tatttcattt
    25801 tatcgggaca aaaatcccta tcgtcaaaag ttatttgggt ggtggttccg tttttgcgat
    25861 cttcgcttct gctgcgattg ctacatttgg gatcttacct gaatatgtag tgaaatccac
    25921 agaaaacttt gtcagcaata tgggcttttt ggacttttat attgctgcct tgattactgg
    25981 tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt ttattcccgt
    26041 tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtgggca tgcttatcgg
    26101 aaatggtttt gcaaattccg ttttatacat ctcattacct gcgatggctg gtggtgttgg
    26161 agccggagcc gttcctttat caacgattta tgcaaatgtt ttaggtacgg atgcttcttc
    26221 tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcttagcta tcatcggtgc
    26281 agcattagtt gctcgtgctg gacaatcaat gccaaaattc aacggcaatg gtaaattaat
    26341 ggaaaaaggc gatcttggcg atggaaaacc tcgaactgtg aaaccttcca ttccacagtt
    26401 aggtgttggt ttgatggtat cattgacttt cttcatctta ggacaaattg gtaactattt
    26461 tgttcctaaa gtccatgctt acgcatttat gattattatc gttgtcatct gtaaaatcgc
    26521 caacctatta ccagagtatt atgaagatgc agctatcatg ttcaataact tgattgtcaa
    26581 aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttgctgaatc tgaatgtatt
    26641 agcttctgct ttgacatggc aatttgttgt cttatgtctg acaagtgtta tcgcgatttc
    26701 agttgtttca ggatttgtcg gtcgtttgtt tggtttatat ccaattgaat caactattac
    26761 tgctggctta tgcaacaact cgatgggcgg aacaggaaat gtagccgtct tatctgcagc
    26821 taatcggatg gaacttattg cttttgctca aatgggcaat cgacttggtg gtgccatcgt
    26881 tttgatcatc tctggtttct tgatgcaatt actttcttag tcaaaaaaac aaaaatacct
    26941 gatcatcaag tatcggcttg gtgatcgggt atttttttga taaagattta caggattttc
    27001 aaaaatcttt tttgcatttt atcggaatga taaccgatgt gttcataaaa ttggtgtgct
    27061 tctactctgt attctgcaga attaagcctt attgtcgtta ttcctcgttt tttcgcttct
    27121 tcttctacgc cagtcatcaa agcctttccg atgcctcttt tttcagcata tttagacaca
    27181 gcaagtgcca taatattgaa cattggatcg ctaaaaatcg attcatagga ctccgcttgt
    27241 acatagccag ctgctttttt agaagtagga tcttcataaa ccaagaaaaa atttttctct
    27301 ggctccttca gcagtttctt catttgtctc accgtaacgg ttaatggtat atcataccct
    27361 aattgatccg cattgatttc acgtagtgct tctgcatctt ctaaacgcat ttcccgtaac
    27421 atccaaatca ccagccaatt tctgattttt taaaatgaat ttttttatca tagtatactc
    27481 tttttttcat ttagaacaat atgtttcagt gattttgact tgcgttagtc tagattctcc
    27541 taatgtttgt aagatgacaa aggcattgta acaattgacc aaaagaacca cgaggacaat
    27601 tacttgaaaa ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca
    27661 caaacctcca ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat
    27721 aaagctactt gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga
    27781 tagagaatat agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac
    27841 attgactggt ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca
    27901 tataaggtac caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa
    27961 gaacgcaaaa accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc
    28021 gttttcaaat aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac
    28081 agctccacta gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg
    28141 tcgcacagtc gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc
    28201 tgcaacagaa tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat
    28261 cccggaaata gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat
    28321 catcttgtat ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat
    28381 tatacagtaa aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag
    28441 tgctaaacga aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
    28501 caaaaatagc tcctcataat tttcgtttgg ttgaacttat taccgcagat gcaagctttt
    28561 gaacaccgtt taagaaagag gtcgtgagcc tgccgttcag ctccgagtca caaggaacaa
    28621 tttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca
    28681 ggagaacacc gtttaaggaa gagactgtga agtcaacgtt ttgacctgat tattagagaa
    28741 acaaatggca aaatagttct tcatatttcg ccgtttttcg agcgaatgcc gaggggcagc
    28801 tgattgaaca tcgtttattt ggaaaaaggg attgtgacaa gacgtttgtc acaatccctt
    28861 tttttatatc ttattaattc attcttttgt tctattcttc ttcttccgcc atgaatgaga
    28921 aacccatatc aaagaactat aaaggttatc aaaacagcgt ttatgactaa atgaattaga
    28981 gttatctatc actatttttc aagcgattta aaccaaatgg catacaatat ggcatacaaa
    29041 aacttcaata agccgtgggg gtttttaaat ttcttcttgt tctttaaaat caatgagtgg
    29101 agctacataa tttgaatcca ctttttcaaa cgtcactttt tgcatcgacg aatgttttct
    29161 ttcccaagat aacgtaaata gatttgactc tggacttata aagtctactt caccttctag
    29221 tattactttc ttatgcaaat attcctctaa taaatataga cttgctaaag catacaacac
    29281 attttccaaa tttgcttcct tataatttga agaacgacca tgttttactc tgttatatat
    29341 tttccaccaa tctggtgtat cttcaggcca cccatctcca aaaggtttta gtgaagtcaa
    29401 tgttaaagaa ttcataaccc taacaccatt atccaaacac attaattcgc tagatttaat
    29461 aacagcttta aaatcagtta tgcttttatt gctactgcta tcaaatccgc aaagttcttt
    29521 gaaaataatc tcacactccg aaccaatcgc tagtagtagt ttttgatatt caatagagaa
    29581 tgttttgaaa ttattctcat cgagcatcac aaaatctgtg gtattaataa actcattttc
    29641 taaatgtaga taatacttcc aataaaaatt tgtaaactct gctttgtcca ttaaatcacc
    29701 tcttttgaat tataacaaaa aaaacacgtc cacaacagac gtgttctttg atttctacac
    29761 aatcagcttg ccaaaaccat ccaatcagtc ctagcatgcc tgtattaaaa ttgaacgttc
    29821 atcatctatc atctttctta gtccagcatg tttgcaacca cacctacaat tttcagtcca
    29881 acaatagatt tcgactagct aagtcttgca aaattcaggc agctaaccct tcatttacta
    29941 ccttaattat actaaatacc cacaacgttt acaagtgtaa tcattctaag aaatctgttt
    30001 agctatgatc gttgtataat ctttaaacgc cgttccttca ttgattgaaa taattttata
    30061 actcttgttt ttccaagcta ctttcatatc gtttgttagt tcataatctt gatcgtatcg
    30121 aataataaac gtcaacgttc cttcaagaat ggtacctaca ctagcaagca cgtcttttag
    30181 catttgtgaa cgcacattag cccaacattc aaatacagtt tcttcactat ccaccatctg
    30241 cccatcttca tcttttaccc gttttgtctt tttaaacttg actctctcag tcaattcatt
    30301 tacattctta atgattggca taataagcac ctctcatttg ttgtactaat gcttgtaccg
    30361 ttactggtat ccgttcgctg ctggcttctt gacggttcaa ataccaatgt tgagtaagta
    30421 atgacaccgc caaatcaaat tgctgataat tatccatatc tttatccgtt gcgctactat
    30481 caatagcact ttttatatat tcgcctgctg tatcaatcaa ttgttgaata aagtcatcat
    30541 caatagtgtg atcgatccgc atactttttt ttatgctatc caaaattacc attttatctc
    30601 tcctaatgaa aaaaaggcag tgggataaac cgccgcccaa tatttttcta tacttttggt
    30661 gttacaactg gcgtaaactc aatatacact gaagcatttt gatcaatttt cttataatcg
    30721 ttgcgaacga tcactgcaag tccttgtgag tagtaatcga atttttccca ttgagtcgtt
    30781 acttgatttc tacgagcaac aaagatagat tgtgcaatat cccccataat catagggaat
    30841 gttccagctt taggattggc aaacaatgta tctgcaatca atactactgg cataccgaat
    30901 aatgatttac cactaggtgc tgtcacatcg ggttgtaaaa tgtaacgtcc atctgaatct
    30961 ttcaatgtat ctaggtggta atatccgctt tggtttagaa ttaccatttt atttaatgct
    31021 gggtctaatg ccacattgta tagttgtttc aaatcgtcca acgtagcagc cgttttctta
    31081 gtgaatgttt ttaataaatc catgatatgc ttattgtcag tgttttctac caatttcgct
    31141 aactgatctt tgacctcttg tacaatattc actgctgaat cttccacaac ctcatttgat
    31201 aaggcaatct taccagcacg agtttctact ttataatcaa ctgaagtaaa catttcagcg
    31261 tcaatatcac caatttcagc aagttcagct tttgttgcta acactgcttg ttggttagtt
    31321 gctactggat atttaccttg tccatttgat actgttttta ctgttgcata ttgagctaag
    31381 ttataatttg aacgtttcaa atcaaagact tcaccgatta cttcttcggg aacaactgcc
    31441 gctgcattta cagtagtgac tccatcacgc acttcgcctt gtgaacggat atattcttca
    31501 tacccacgca attctgtttt ttcgttatcg attaaagttt tttccatgtt attactctcc
    31561 ttttgtgctt tagaagtgga ttctaagcta ttgtttgttt gttttgcttg gttgttactc
    31621 ataaacgatt cgtaagaacg cttatttact tggacatttg atgaatcata agcgggaacg
    31681 gtcacgacac taatttcatt aagtgctttg attttatcta ttgatcgttc aattgtgcca
    31741 tcttcttttt tgtcgaatga atctaatcca agcacgaacc caaaggacat agaatcaaca
    31801 accccttttg agatattctc atacacatca tttgaatagg tcgtgtcggt tagctctgct
    31861 tcaaaatgta atcctgtatc atcgacattc aatttcaacg tacctgcttt gacactagct
    31921 agtggctttg aataatcgtg tccatataat aagaacacat ttgataaatc cacctctttt
    31981 aatgcttcgg gtgtaatcac ttctacaaag ccgcctaaat cttttgacgg ttgcccgaat
    32041 ttcaacgcat agcctgaaat agttttgccg tctgttggtt gtttttcatt ttctttctct
    32101 actttgggag aatcggctgt tagctcagct tcttctgtca gccgtttttc cttttcttct
    32161 tcattattca actggtgtaa ctccttcctg ttcttttaat tgatatttct ccaacgtatc
    32221 taaatacgta aagttcaaac ttgctagtaa acgatcgcca ccatccatgg ggggtagccc
    32281 cattttcgac cgcccctcat taatcgtgag aagtgaccct ttgacctgat ccaatacatt
    32341 ttttactttt gtttcaggat cagtctctag taactgatcg gaattaaagc ggatattggt
    32401 ttcaagtttc gtatctaatt cactcacaaa cacattaaag taatgaatca gcgtactttg
    32461 gatatactgg agattacttt gaacggtgct agaatgttca ttttcaacgc ctaaacgctc
    32521 aatcggtaca ccaaacgcct tggcaatttg ttttgtgttc caatcattgg aattgataag
    32581 cttcaaaaca tcggtgttta tttctaatgt tttgtagtcc attgtttcat caagaatgat
    32641 cgttctaaga gcattatctc cactacttga accgttggct tcttcaaact tttcacgaat
    32701 tgcgttcttt gctgatccgt ctaaatctga cttatgaacc ttcaaaatac ctgacccact
    32761 gacaccacga gtaaagaaat tgtgcaatgt gcggttgcca gcttgttgaa ttttcagttc
    32821 atcacgtaac gcataaagtg gtggtaatcc tgttaaacca tcttgggtga aatatttgaa
    32881 gtgcaaaata tcgctagact tcacacgtct ttttttatca ccaatctgat aagacaacgt
    32941 accattatct aattgagtaa ccgttacact tgagttaggt aataagtgaa tttcttctac
    33001 cttttcaccg ttgcgtttaa tctctgcaaa gctattaccg tttagcaaca tattgaccgc
    33061 caaagcaaac tttaaatgcc aaccatccat ttctgaatta ggtttctcgt ttagtaactt
    33121 caccagttca ttatcagctt gtggcatatt gtttttgacc aattgaatcg gacttgaagc
    33181 aatatcacta gcaataattc gaacggctgc aaacacatca ctatttctta atgcacgaac
    33241 gcttgtaaag ctggtggtgt aatcatccga ttggattgat accacatgtt gtaggaaagg
    33301 atctcccgtt gtattttgtc tcgctttaaa aaatgccatc ttttaacctc ccttctgttc
    33361 tgtatttagc atgaccgcta ccccaataag cactatgccc agcgctaaca agccatagta
    33421 gacatttgtt agtaaggtga tagcaaccaa cacacacacc aatccaagaa gtaaaagaac
    33481 ggtatgaatg taattagaaa gaaaattctt cacttgtata aaattcattg tctgctttcg
    33541 ctccttccgt tgtggtgaag taatccattg caaacacata ggcattgatt aatgcagcta
    33601 ttggatcaat tttgttactg ttctttgatt tattaatctg aatgccgttg ttatccgttt
    33661 ttaaaatagc gttgttcact gcatgggtga gaatcgtatt tttattgtga ataacgttgc
    33721 cttcataaac ttgttctcta aaagttcggg tcggaacgtt tagagtaatc gttccttgtc
    33781 ttacttctaa cattgggtag ttggcttttt cagctttact gataagcgaa ttagcgttat
    33841 acgggtcata acaaatcccc atacattcca aatcattttc ttgaatcaaa tcttgaataa
    33901 actgaaatac ttggtcatag tccacgattc cactttctaa ttgagtaatg gaacactcac
    33961 cagctttttc tagttctcga taaggcaaac cgtcgcgctt ttctttgtct tgaagcccat
    34021 atttggtggc tacaaagcta tgtgaatcac aataaagttc gccgttatct agcggtacga
    34081 tccatgaaac gctagttaaa tcatctgttt tagataaatc cactccgata taaacgggct
    34141 tgcctgtaat atcttgtggt tctacttcgg ttgcctgcca gtcttcagca atcatatagc
    34201 tgtcctcact cgcttgtctc cataaattga agtttttcac caatacagaa ttaaggttat
    34261 tttgtttcaa agcaaggttc acatcatctt gaatggttgg aatcattact tttttgattt
    34321 cttcactttc aaaaatcgga ttggctttga tccatttctc ttgatcgtga atttcttcgg
    34381 gatcgtccaa ttcccatatc gctataaagt acctgtcggc ttgttcttcg ccttttagca
    34441 cacgatctaa caataagtat tcctcgtaca taggaacgtt taaatcaagc ccagcggtac
    34501 taataacaca caataagccg ttcttttgtt gggtcattcc tgacttaatg acgttgtacg
    34561 ttttacgagt ttttgcttcg tgccactcgt caagaattgc ggttgttggt gcaaacccat
    34621 ctagcgtgct ggtttcacta gccagtgcca tagcgaacga attagagggc aagtgctgaa
    34681 tcttagagtt cataattttc agttgtggtc ttaaaaactt actagacttg accacgtttc
    34741 taagtgaatt agacagcata tcatagccca atttagcttg tttcaaagcg ttacttacaa
    34801 acaatacttg ccttgcttct gctggttctt gttccataat caacgcattg gcagccatgc
    34861 cacttgcgat atacgttttc ccattcttac ggctcatact ggtaaacgct cgattgaatc
    34921 gcctgtaatt cccttcttta gtacgccagc cataaagact gcctagaatg aatttttgaa
    34981 atcctaacat cttgattgct ttaccgtccg tagatggtag caactcaatg aatttaatcg
    35041 ctttggtggc ttgttcttca tcgaacacat aagggaagct atctgactta gaacgctcca
    35101 aatcgcttat atgacgctca cacgcttgga taattttctt gggtgcaatc agcttacctg
    35161 ataggacttt ctcaatgtaa tcattcatga attcatcaac tctttgaacg ggtcttcggg
    35221 ttcatcattt ttaaccttgt tcaaagctag ttttgatcgt gattctaagg tcatacctag
    35281 tgaggtggct tgttttttca aatcactcat agcttgtgat tgaacccgaa ccgctggatt
    35341 ggctttcttt actccgtttt cgcatgtgat aaacgtacct gattttctta tctcggcttc
    35401 ggctgttttc attcgagcaa aggctaaaca ataggctacc aatgaaccat aatctgcttc
    35461 actcaatgga taatcttttt ttaatgttgg tacgatacga ttccattcac ttctagcgct
    35521 cgctgccatc cagtcagggg gcgtgatatt tattaatggt tgctgcttga acaattcttc
    35581 tctagcgtcc acacggattg ctttttcttc acttgatata ttgccttttg tatcgtgtaa
    35641 tattttaggg tgtcccatgt tgtcctcctt tcagacaaaa gaaaaaggaa cgtaagcaat
    35701 taagctcaca ttccttcgtt tttcgatcag aatttttctt tatctaattt atctatataa
    35761 atgatttttc cgttctgcat ttgaatggtc acttgaccaa aatgaggtaa ctcaatggtg
    35821 cgctgtttcc ctgttttatc agtaataaca attgtatttt tcaataaatc tcctactttc
    35881 attatatact ttttcacttg tgattacaag tgtaatcgtt atttgtaatt acccttatgc
    35941 cttttcacaa cggttatttg taccaaaatg agtaggcatc gattgtcagt aagtttcaca
    36001 ctatgccccc ttaactcaaa gggtactctt ttctcgtctt tgtctttcat tggctgtctt
    36061 ggaattatgg tgtgcatggc ataaagaacg aaaattagtt tcatctaacc gtctattcca
    36121 atcatctttt agttcaattt tgtgatctac aacatcagct ttccttatca agccttcttc
    36181 taggcaatcc tcacatactg gatgatttaa ccgatacaag tatgaagcct ttcgccatgt
    36241 tctactttga tagaattgaa aatatttacc ttcgctttgc tttctttctt cacgcttaat
    36301 tgccgtttgc tttgctttat gcttcccaca atacttctgc ctataatcaa tcaatgtttt
    36361 acatccagca tgattacatt gttttttaac tgccatagat taccaaccaa agcgatctcg
    36421 ttcgtcagaa tcatcttgtt cccattttga tttgtattca atataaggcg aaactatctt
    36481 caagcacgtt ccgtctttaa aattaacttt agtgatttta tcttcctcaa aactaataaa
    36541 gtctacatct tcttgagtgt ttgaatactc aatgtgtttc tcaccatcga agtatctaat
    36601 actttccata tgcataatta ttctacctcc aataaattag ttatcaattc atcatctgtt
    36661 agtagcaaag ccaagaactt atcatggatg tttaaaaaca aattatcctc attcgatgta
    36721 agctctcgtt gtctcgctcg atcatatagg ttaagcagac aattaaattc atccattagc
    36781 tcacctgtat catcatagtt gccactatct accaatgatc ccactactag cgattgacac
    36841 cacgctactg actcctgcag ccaatcaggt tcttcttcca ttatctttaa tacttctgga
    36901 tcaaatgtgg aataatcttc tgttaccaat cccacactaa atgccagcgt gttcattaga
    36961 aaccgatcca tttcatctgt atattgaaag ttcggtgctt tgtttgttga aataatattg
    37021 agcatttact ttcctccttg attcgtaaca cgtggtaaca cctacgtaac aggtacccgt
    37081 taccactcaa tcccaacggg gacaagggtt ctagcgtttt ggtaacaggt aacgggtaaa
    37141 atccagtaac attattcccc agcatattag ctaactattt caaaagtttt aaggaaataa
    37201 ggtgttaccc cgttaccaaa ttgctgtatc ccttggggca gtaagggtaa actagtaacg
    37261 ggctaggtgt tactgacccg ttactacccg ttactttttg tactttccag ctcgattttt
    37321 attttcatag gcatttgact tattgtaaaa tcctcgtcgt ttatttcttt ttggcagttg
    37381 cttccgttcc caaccaggaa tactgctaat aatcaaggca atctttttag tttctgcatc
    37441 tgatcgacca ttcaataaat cctttgcttg tttatcaaaa acagcttcca aaatatcagc
    37501 ggtgagtacg ctatcaacta aataaaactc ttgttgcata gtagctccat tatagaaatg
    37561 ctgtaaattt ttctcattac atttactgtc aggatagttc tgataataag aacgtctcgc
    37621 ccacgctgga gcttcttccc atttatacgg gatttccatt tccaaatatt tagtgattgc
    37681 ttctttaatt ggattctcca tcttggcatc ctcttgatag tcttttgcaa tttctaagac
    37741 ttctttatct tcatcgggac taaaatagat tcgttgtcct ttatcaaaaa gcacctttgc
    37801 ttcagctaac acttgaagaa aatattcatc ctttgtttta aacggattca tctttggctt
    37861 attcttacaa ggcaaaggat aaaaacggcg gtttcctgta tcatctttca aatactgccc
    37921 atcattcgac gttccaataa atacacattg ccttgcccaa gctatgacat tccgaccata
    37981 aggaggtcta attttatcga tcttggcact gatgaagttt tttatctgtt caattttagt
    38041 tttgttcatt gaagataatt ctccaagttc aataattaca ttgccttgaa gctgcatata
    38101 atcatctttc ttttcaccta gcgaatctaa tgaatcggtg aaaaaatcat ccgtgtaaag
    38161 taatgctgga acggtactct caccaatccc ttgcggtcca tccaaaactg gaacgatctc
    38221 aaactttatt cctggtttat agatacgtgc gactgatccg actatccaac gttttgttac
    38281 ttctcgtgtg taaaggttgt cgtctacccc taaaaggtca ataaacagtg tttccagtct
    38341 aggctgttga tcccatttaa ctttttcgat acgttctttt actgggttga aaacattctt
    38401 tctagccaca tttactactg ctttgtgtat tttgttgtca tcaaaaacta cattgtagtt
    38461 ttcttcaata tatgccgtta aggcatcctc aaaactgtct tcccattctc cagcggtacg
    38521 attgatccaa ggagaatctt ttaataggtg aatgtatccg ctaaattcgt tataagcaat
    38581 tgttccagct aaattgctat cattggttaa aatcaattct gcattcacaa cactgttact
    38641 tttaatctga tcgtctttat tgcatcttaa tcgtgacatc caggttttca attcaatgat
    38701 attgtcttca cgctcgctgg cttcgggaaa gtctaaaata ctatctaatt tatgcttatg
    38761 agccatgagc tttccccctc aaatcttttt taatcatcga tcgaataatt tgattcactt
    38821 ctttatcttt tagcggtggt tcattgtacg catttgctgt ataaatcaat tctgctaaag
    38881 tttgattatc tacaccgtgc catagtaacc aaccgcataa cttagttaaa tgatcgtttc
    38941 tactaccttc gccagcgcct tgaacaatca tatctaattt ttttgctgtc cctgtttttg
    39001 ctacgggtcg gtattgagtc tttatttctt gcggtttttt tagcagtagg ttcactagcc
    39061 aatcgggagc tggtgcaata ttatttagag atacgttttc aataggttca tatgctctcc
    39121 caacacttct tgaaataatc atagttggcg ctattggaac tcctttagtg ataatatcaa
    39181 tcccgcttaa acttttacct ttatcatcac gcccgaagat atcagcaaat gcacctgttt
    39241 cttgttggat aattacacca tcaggaattt taaagaagaa atggattcct ttacctggtg
    39301 tgatttccgt ataagtagaa ggaaatggat catacattga agcaagtttt ttataattct
    39361 caacgccgtt tcgtgtttca gaatgttgat ctaggtcaac taccaccatt tgatgatctt
    39421 caagcattaa cccaatattt ctagttgcat cttccgtcca ccattcatta atttgattag
    39481 aatcgttagt tgcatcattc caaccactag agccttttat tggaatttta gttccaggag
    39541 ataagggata aattgaccat cccgactttt gtaattccgt tgctgcttga taattatttg
    39601 ccaataaacc tctcctcctt tttcaaaata ctggtataaa tcattcagac acctccatga
    39661 gcttcaactg ctcaagttcg tatttcaacc catcccgaac aaattcagca ccttttaatt
    39721 gattctgata ctttacccat gtattaaatg ttttcaccct tgcttcttgc atatcagtaa
    39781 tgtttaacca tgcggttaaa atctgatttt ttagctcgtt gatttctcga caaattattt
    39841 tgtgttctgc atgttttttg agtacataca aaactgttag tttttcattg aatgaatttc
    39901 caaagtaggt tttcccgata ttattttcta gttcagcgat cccttgatta atttcctcta
    39961 attcaaggct atcgagttgg tttaatagtt ttgttttgta catctactta tgccctccag
    40021 ttcttaattg atagtcgtac tcgtcataag cagtgaagag atataacgct aatcctgcaa
    40081 agatagctat ttttgcaatt aatggtaata agccgaaaat tccgccgatt aaaatgcttc
    40141 ctataattaa gtttcgtttc ataatggttc cctccgattt tttaatatgg tataatcgga
    40201 acaaagaata tcgggtttta tcccaattaa gttgccttta tcctgtccgc caagactgtt
    40261 atggataagg ctttttcttt gttctcgatc atgttaatgc tcctaagttg tctgcaattc
    40321 agcagaacga ttataaattt tctcactcac tgaaaactgc aacccatatt tttctttaac
    40381 agtcattaat tctactgtct catctaaaat aggttcacga tcaaccaaca tttcaggagt
    40441 catatctttc ttttttacca ttttggaatg accataaata gttgatacag ctttattggc
    40501 tatcacattc gctttaatgt agtctactgg ttttggttca gtaatagcgt ggcttaattt
    40561 agtcattgct tctttttggt gttctttgtc tagcatgcgg aatacttgaa agccttcaag
    40621 tcctgtggac tggcgtagtt ctttgatgat gtcgaaaatc cagtcttgaa atgcctcggc
    40681 ttctttttta cggcttttga atgccatgcg gtaaatattt tttttcgttg atgatgttta
    40741 catcttgtgt tctgcccaat gaatcgatga ccttactagt agtaacccca tctttaggca
    40801 aagagtgaat ggctctagta acctgtttaa gacctaacgc ttccgcaaca tctttcgcca
    40861 ctgcccacca ttcatcatta atatcgacaa atcttataat gtgtccgttc caaatttcag
    40921 ttttcattca acgtcctcca gttcaagccc tagcaagctc gctaacaact caacttgctg
    40981 atacaaaatt tcttgatact cttcaataga aagtcgttct ttaaactctg cttgtactaa
    41041 atcgttcaag ccacgcaata ctccgcttac cgttggttct tgtggtagca atttttgata
    41101 gtccatttgt tcgtacaaac attcaaacgt ttcttctagc gctttgcctt ccaagtttgc
    41161 taattctgcc gctgtgtctt ctgtaagaat tgttgataat actttttcga ttgctttatt
    41221 ttgtgtcgat tccattatta tttcctccta ttaatccctt tgcccccacg gcttgcgttt
    41281 atttttggta ttcttccata aagcgatcac attcatcttg tgaaattctt acgactccat
    41341 caactataat caactttaaa ccgttaggaa catatttctg catcatagta ttgtatgaaa
    41401 cgttcatata cttagcagct tgtgccttgt tcatatattt tggaaactgg tacttttttt
    41461 ctaataatga aagtaacgtt ccttgagttt gctctacttg ttgaacaact cgatcgtcaa
    41521 taattttaaa agctggatca tcaagcgtga gtttgtcaat ttttaattcc atatttatcc
    41581 cccctcgtta gcatacattt ctatacaaag attttaaaaa aatgcaagag gctcttgaat
    41641 acatttctat acctcttata aactcaatat accatcatac cttttcattt gcaagaattt
    41701 taacatactt ttttgaactt ttatgtttca cacatattta aatcgtgata tagtagagaa
    41761 aatatatgaa tggtggtgaa aatgtggcta gaaaaaaata ccccgaagca gtggagacag
    41821 gacaaagaat tagactggct agaattgaaa agggactctc aatggaacaa cttggaggta
    41881 aattatcccc accggccagt aaaggtgccg ttagtaattg ggaaaatggc tataatcttc
    41941 ccaataacac caggcttaaa caactttcaa aggtattaga tgtatccact acctatctat
    42001 taaacggatc ttatacatta agagatatgc atatgatgcc cgaaattaag cgaaatgtgc
    42061 ttgaaaagca attgaaaaaa actattgaaa aaaataactc tataattgat tctaatcttt
    42121 ctaatgctat caataacatc gaagaagata acctgactgt ctcacagaag atttatttaa
    42181 caaacgcaat aaaatatctt aaaacaggat ctcgaattga atttcctgac gggagtaccc
    42241 caattgctta tctcgcagct cttctaaata cgcttttacg atatgactca ttaattaatg
    42301 attcagaaaa aaatacagat gagaaaaaag agtatcaaga attttatgaa aatgatcttc
    42361 taaaagagtt cacagctctt gttactgagc taaataaaca ctattcaaaa taataataaa
    42421 ctgcctcctc caaccgcccc cacggcttgc tacactatgg agggaaaact attatggcaa
    42481 cattcaagca atatgaaact aaaaaaggta aattttggct ctatgaagcc tatcttggaa
    42541 tgaacaaaat gactggcaaa cctgataagg ttcgtagacg aggttacaaa acaaaaaaag
    42601 aagcccagct tgccttgtca cgcttgcaag tggactacga taaaaacggt attaaaaaag
    42661 cgaacaacga aacgtttaaa gaagtttatg acttgtggct agaaacatat aaaaccactg
    42721 tccgagaagc caccttcatg aaaactgaaa tcaagtttag aaagtggatt cttccaaaat
    42781 atggaaatct tcgtgtgaat gaagtcacgg taaaaaaagc ccaacaaatt gtaaatagct
    42841 gggctgaaac tactgaccaa tacaaggtac ttcattcaac ttctaagcgt atttttagct
    42901 acgctatcaa tcttgggatt attgagacta atccactaga caacgtatta atgcctaaaa
    42961 gaaccaccac taagcataaa gaaaaggtca aagtttacag taaagaacaa ctgatcacct
    43021 tgtttgatta cctaaacagc aaacctgaaa cttatcgaaa cgactttgat aaaacgttac
    43081 tacgctttct cttttatagc ggggttagga tcagtgaagc ccttgcattg aattggtcag
    43141 acattgattt tcaagaaaat acggtcacca tcaataaaac actaagccaa tccaaaaatg
    43201 gctataaaat cagtgatcct aaaactgatt gtagtgctgg ggttcttcca ctagatgaaa
    43261 gaacaatttc tatattaaaa aaatggcaga ttaatcagcg gaaatatatg ctgacacttg
    43321 gtgtaactga tccgactatg attttttgtg gtatctataa agaactaatc acacaccacg
    43381 ctatttatgc aagattgatt actatttgtg aaaaagctat ggttccattt ctcggtgtgc
    43441 atgtagcaag acacactcat gcttcaatgc tcttggacgc tggagctact atggtagaag
    43501 ttcaaactag attacggcat acaaaaatta gtcagacgat cgattgttac ggtcacttgg
    43561 caaaagaaac gaaagaaaag actgttgaaa aattagtaca acacttaaat attgactaga
    43621 tggcatacaa tatggcatac agtaaaaaat aaaaaaagga gaaaccctat catatcaagg
    43681 tttctcctag ctttatagtc tattcttctt cttccgccat gaatgtattg aatacttctt
    43741 caatcatgtc ccattctgcg tctgtttcga tttgttctaa ctcgccttct gttccatctt
    43801 cgttttcgat gtatgcataa gcttgtaatt ctacatcttc atcttctgaa acaccagcag
    43861 gatataaaag aacatagtta cgtccaaatt cttcttgtcc gtcaactgtt agtaggattt
    43921 catataatgt ttcatttcct tggtcatcca ccaatgtgat gtgttcgtgt ccttcatggt
    43981 cgtgggaatg gttatgttct gtcataagat tacctctttt cttttattat taaaataatt
    44041 gcttacctga gccgtctaaa taattttgta agatcatcac agctgctaat ttatcgatga
    44101 ctttttttcg tttggctctt gaagtatttg cctgctctac tagcatacgt tctgcctgaa
    44161 cagtggttaa tcgttcatct tgataatcaa ctggcaagga gaatagttct ttgatctttt
    44221 ctccgtatga catggaagct tctgcccttg gtccgatgga attgttcata tttttaggta
    44281 atccaactac aaaccggtct acttcatatt gtgctactaa ttccttcaac cgatcaaagc
    44341 caaactcttc ttctgcttca ttgatccgaa tgatctctac tccttgagct gtccagccaa
    44401 aggggtcact gatagcaaca cctactgtct tagaaccgac atccaagccc attactctca
    44461 taaattcact ccatgatttg agaggtagtc cttgacaatt acttccatga tctcatcgcg
    44521 ttcgtgacgg cgaatcaaat ttcgagcatc acgataacga ggaatgtagg ccgggtctcc
    44581 agaaagcaag tagccgacaa tctgattgat tggattgtag cctttttctt ccaaagcccg
    44641 ataaacaatc gctaatgttt cgctcacttc ttttttgcga ctatcgtcaa aaccaaaacg
    44701 tacggtttca tctgtaaaac ccatgattct acacctcttt cccgcaaggt aattccagct
    44761 taccttctac aaccttattt tactcgaaga aagggaaaac tacaaacaaa tattccaaac
    44821 ttccgaataa attaagaaac actatttgta tgtttttttc cttttttctg tagctttatc
    44881 aaaagtactc ttttcataaa gtatacgcta tatttctttg aatgtatgtt tttacacaat
    44941 tttttcataa tattcataaa aaattcgaat agctgctact aattttttgt ttttgttgct
    45001 tgtcctgtct cataattgat cgtgtagcca tcttgaacat tgtagataaa gacattgaat
    45061 tcaatttttt tgtcttcaat gctttctgct tccaattgca ctcccctggc taccagttca
    45121 ttcccctcaa aatgaggagt gacacggtag cgtacatgat gatttgtttc tttgatatat
    45181 gccgcaatat cattttcgtg agcaagcatg tatggagcat tcaacgaacg tgtccctgtc
    45241 atcaagtttt taatgttgtt attttgacca gtcagctgga aaccaattaa atggctgcga
    45301 ttatataacc attgcccgtc acttaatttc ttttgtttcc aacctgtcgg gtcaatatac
    45361 aaaggctctc tcttttcagt agggaacaaa tcttttccaa gcatagcatt ggcttgtcct
    45421 actctgttca atttatcaat atttgaatag ctttcccatg ttcctttgga aaggctaaga
    45481 tcctcttttg taaattccgg ctgattccca ttgatttcta tttcttgatg ttttccatca
    45541 tattctggca catccgctac ttgagaagct tgtggtgtgg aatcaaaaat agttgtaatc
    45601 tgctgaaaga tatctgaatc tttttgtgtg gtggaaacac cgaatgcccc tgcaatcaca
    45661 gcagcgacga tccccacgat cgccttggtt gtttttttgc tcatttcttt actcctttac
    45721 taacagctcc ctaaatctta acatatgttc ccctataaat aaatactaga aagaaataga
    45781 aacagcaaaa aataaaacct gttttaagat ggcttaaaaa tacaaaaaag agacggattc
    45841 ctcgtctcta atcagtcacc actctatctg taaggtattt attattattc aaaaattttc
    45901 ttcatactca agacaataca ctgatttcac aaccgcttgg taaacggtgc gcaaaagctt
    45961 gcatctgcgg taataagtcc atccaagtta aaaacataag aagttgtttt tgcttggctg
    46021 ttcttattac ttgttgcaga gcagcttttt cacaacctat tttaagcggg tgacgggaat
    46081 cgaacccgcg acatcagctt gggaagctgg gattttacca ctaaactaca cccgcaatac
    46141 aaaaacagta tacgcctctt ttattccttc ctcaagtttt tttattcttt acgcttctgg
    46201 tatgttttgt agtaaaataa aactaatcaa tcaattattg gagaagatgc tatgacggga
    46261 aaagaattag atctgttgct ggacacttgt ttactcgctg ggaaaatcat gatggaaagc
    46321 aatgcggaga tgtatcgggt agaagatacg atgagtcgaa ttgctttagc ttctggaaat
    46381 ttccgtttgg tcagctatgt cactcaaacc ggtctcttta ttggtcttga tcgtacctcg
    46441 accatccgaa tggaacaaat taccaaccgt tcgattaatt tagaaaaagt agtaaaagta
    46501 aatgatcttt cacgtaaata tgttgcttca gagctaacat tagaagaact ttactgcgaa
    46561 ctgcaagcaa tcgaccgaga ccgttctttc tttcctgtct ggttgcaaat cgttagcgcg
    46621 gcagtgatca gtggaacaat tatggtgtta tttggcggaa agatgaccga tttacctgtg
    46681 actttagtca ttggaggatt gggatacgca gcttatctat atagtttgaa attttttaga
    46741 atcaaatttt tatcggaatt tttatcttct ttattgattg gcatagccgc tatctacagc
    46801 gtacgttttg gcttaggaag caatcaggat ctaatcatta tcggatgtgt gatgccttta
    46861 gttcctggag ttcaaattac gaacgctatc cgtgatttgc tagctggaca ttatgtctca
    46921 ggagtttctc gcggaacaga agcgatgatg actgctacga tgatcggttt tgcgattgct
    46981 tttattttcc agctttttta ttaggaaagg aacacaagta tggggacgat atttattcag
    47041 ttttctttta gttttttagc gactgcggca tttgccgtta ttacaaatgt acctaggcgt
    47101 tcattgattt gttgtggtct ttctggtgct tttggctgga tgatctactg gatctgtgtt
    47161 caaataggcg gatctgctgc ttttggttca ttgcttggtt ctttaggagt agcattcatc
    47221 agcgatcttt tctctaaacg tttgaaaatg cccgtaacga ttttcaatat tcccgggatg
    47281 gttcctctag tccctggtgg tttagcttat caagcggttc gaaatctcgt tactgaatcc
    47341 tatcgagaag cggctcatta tgcggtccaa gcaattatga ttgctggagc aatcgcttta
    47401 ggtcttgtat tatcagaagt ctttaaccat aacatccgta atttcaaagt aaagcgtgac
    47461 gcaatcatga tgaaacgaaa aaaacggctt tttaaataaa cgaagtgtaa caaagaaaag
    47521 gttgtgaaag agacgttcag ccttgagcga tgacaaaata tctcacaaac attgcgacaa
    47581 gtaaccgcag gagcaataag aagtaattat gagtattaaa aaaagttttg taaaaatagc
    47641 ttctcacatt tttacataaa attgacttaa tactgagaaa ctgacttttg aacaccctct
    47701 atctgtaaaa aaggggctgc gacatgattt ttgtcacggc ccctcttctt tattcaaatt
    47761 ttttccaaaa cgttcgttga taataaacga tccatagagc ggaaagtatt agaactaaac
    47821 cgatcacagg aatattcact aaccaaaatg gataaaacaa agccaacatt ccgtataaga
    47881 cgataagaat aatactgatg atcaatgaac ccatcatagt tgcgactaaa cccaaacttc
    47941 ctgaacctct gttaaataat tggttaatat tggtccagtt cagcagcagc aaccgataat
    48001 ctctagcgaa ataacgtagt gacaataagt agcagccgaa taaagaacca aatagcaagc
    48061 tagggataaa aaacaaaggc agctgaaaag acagtccgct taataatgcg atcccaccag
    48121 ttaaaaaact ctgcaatatc catccgaatc tgaacttttc ttttaaatat tggttcatag
    48181 agattggcaa agaacggata aacagaaaat tttcttgatc caaagaaata agattgctga
    48241 taaaagaagt ctgattaact gttaagaaag ccaatgcgat ccctaccagg aaaacaacac
    48301 cgattaactt attatctaaa tcagttaatt ttatttcgcc tcctagggca aaagcaagaa
    48361 taaaaatgat tggagttaac aaggaagaag aaagaacttg cataatcaaa ttaggttctt
    48421 ttactaattg agcattgtaa ctaaataaaa gctgatgcac attttggttc tttttatggg
    48481 ttctttttat tttgaactca ctgtttgaat cagtcagttg ctctgtaagc tttggtacta
    48541 tcagctgttt tacagcaagg aaaaatccca gagccgtgat agctagtatt ccccaaccca
    48601 ataaaccttg ttgagaaagt ggctgactgg cagcatcata gaatggcaat aatatcgaaa
    48661 tcggatgccg atctgttaac tcattttcaa tagtccccgt ttgatgattc atccacatga
    48721 ttccagcaaa tgcgatcagc atcgagctgc caagcaagat actagaaact gtttttctat
    48781 gttttttaaa cactgctgtt cgagccaaac caaaaacaat caaactagcc agacaaaaaa
    48841 gaataatcaa aaatagagaa aacaaaagga ttgagataat gatagtaagc aaaatcccta
    48901 gatcagctcg ccatccggtt aaaataaaca tgactagaag cggaaaaaca aaaggaatga
    48961 tggtcaaagc aactaccaaa atctttgctg aaaaaacctg ttcttgtcca aaaggcagag
    49021 gcaaaaatac ttgcaggtca tttccttcaa aaaagatatt ataaatgact gatatacttt
    49081 gagttaaacc taacatacca aaaagtgcca cgtaataagt aaagaaacct ggcaatttaa
    49141 caaagttcat agcaaacata gcaaatccgt aaatcagtaa aaaaatcagc cctgaaaaaa
    49201 gattttgaga caaaagatag atagttaatc gctttccctt ttttcctttc tctcttgctt
    49261 tattcgtgag ctgtggatta acatataaaa gattaactcg aattaattct aataattgtc
    49321 gcttatacat acggtccatc tcctgtcgct tgccttccag ccattttcaa ataaatcttt
    49381 tctagcgttt catcaggtga gccattcaat aattcactaa ctgccccctg ataaatcaat
    49441 tcacctttct tcaaaatagc cagtttatcg cataactgtt gtgcggtatc caatacatgt
    49501 gtagaaaaaa tgactgtttt tccttttgcg gcatgagcct tcatcatttc tttcaaatca
    49561 aatgctgctt gaggatcaag tccttgcaaa ggttcatcca atacccaaat atctggatct
    49621 ggcagcaacg tgccgatcaa aatcgttttt tgacgcattc catgtgaaaa acttgcgatt
    49681 gtttcatttt gatgactata catatcaaaa agcgctgtca attctgctaa acgcttttct
    49741 tttttttgtg tgtctaattc ataggcagct gaaatcaagt cccaatattc tccagccgtc
    49801 aattgtaaaa aaatatctgg ggaatcaggc acataaccga ttttttgttt gatactcaat
    49861 cgattttccg tcaatttcat tccatctact aaaatcgttc ccgatgatgg ttcaataata
    49921 ctaactaaac ttttaatcgt agttgatttt ccggcaccat tatgtcctaa aaatccaaaa
    49981 atttcccctt gtcttatcga gagagacaag tcttttaatg cttgtttttt cccgtaactt
    50041 ttacttacat tgatgaattc aatcatttct gtactccttt tgtttgttat tactttttat
    50101 tgtacccttc gttattggtg gagtaaatgt caaaaagagt gcataacaaa aaaggataga
    50161 aacgactagg ctgctacttg ggttgttctc ttctacagga aaacactctt ctaacaggta
    50221 agatatgagt ctttgttttc tttaaaatga ttcattttct atcttttctt gcataaaatt
    50281 ctttagttta tcaatacttc tctttcccat ctctagttgt tctccatttg caaatgttac
    50341 tatttcgttt actctgctaa tagatgtaat gttttcagta ttaatgatat aagcttttaa
    50401 atctttacat aaatactcat attcgagtga ttttttatat tttttaattg tgccgtttac
    50461 gagaatctct tcatctttca atactaggcc tattttattt ttataacctg gcatgctcat
    50521 tagataaagg atttcatcgt aatggatata gtgatcgcta ttaccataac ggacagttgt
    50581 ccaccttttt ttcgtagcat gttgaacagg atagttttct ttttctttca ataagtaact
    50641 ttggatgctt tttttatttt tttcataagt gaattctttt atcaaataac cactaggcgt
    50701 aatctttcga ttaataacag ttattgcttt attcggatga gacgttagat aaacaatttt
    50761 acacttttca ttcttttctc taagcatttc gcctagttcg ataccgctat aataggcgtt
    50821 caaatcgatg tctaggaaaa aaatatctga ggaatagatt tcattatttt taatgaattc
    50881 aacaaattgt ataacgttca atccctgaac gatctcaaat ttccaaggac ttaataaaat
    50941 tctggattct tccaaaattt ctactagcat tttttcaaaa accaaactat catccaaaat
    51001 aaatatacgc gttaccataa aaagtacctc cactcgatat tttactatca aaatcatttc
    51061 atacaacttt tcaacataca tgttaggaat aaattgtaat tctcttcaca atcttttcca
    51121 acacctttga aaccgatatc aaatactttc aggatgctgc ttctaaaata aatatcaaac
    51181 aaatgaatac atcatgcaaa aaaagccaga caaccgacgt ccttgcgtgt cagctgtctg
    51241 agctatgttt atttattttg ttcttttaaa aagaacgata cacatactga tttttcggag
    51301 cagagacttt ctcagcgttt gtaacaacta cagatgggat ttcacgcttg aatggttgat
    51361 aatagtctga ttggatggtt ccttctattt tataccattc atcattttta accgttactc
    51421 cttccggcat atgcgtcaac aaaccaaaga ctcctgaatc tgccacacaa tggataatgc
    51481 cgaatcggaa caagaagata tctgtattgc tatcgttcgg tgtttggtaa acaaatcctt
    51541 catagctgat ttttttgcca atgaattcgc tagggtaatt ataaattagc tccataactt
    51601 ctaaatagtt ttcatctgtg atcttgatag tttgcttatc cccatacttt tctttcaact
    51661 cattcatttg gtctaagtag tctgatttgt tgaaataaat actggtatcc ggctttaagt
    51721 attgtgtctg catctccgga tcccctactg attctttact tactgggaaa ttaaatcctt
    51781 tggcttctac gatcgtagtg tcgagactaa ctgttggaaa caacgtcccc acgattactg
    51841 gcaaagctag cagtacataa gcgattccac gttgataagg ttttgacaac ccatggtcat
    51901 gatcgtgctc gtgtgccttt tcttctgctt ttccgttttt gacccacaaa tacagctgaa
    51961 ctaaagccaa aagagcagat aaaatcattg aaagaatagc taagtagcga taatggacat
    52021 tgatatattg atcgagtttg ccagaaactt gcaagtacat catcaattcg aaatacccag
    52081 ataaaatcaa aaaccgcagc atattttccc tcctaaataa ataatgtgaa tccaataacg
    52141 ctaagggcaa tcagtccgat cagcgataaa ataaagcgtc ctgtaaaata tcgtttcatc
    52201 atcagtagat ttttgatatc gaccattggg ccaaagacca aaaaggcagc tacaggtgct
    52261 gtgccgaaca gacttaacaa agaagatcct ataaacgcat ctgcttctga gcaaagagac
    52321 atcgtaaagg ccaataacag catgatgata atggctaaaa tctttgttga gccgagcgtt
    52381 agcataattc tagttggtaa ataagtctgc atcgcagctg cgattaatcc gccaatgatc
    52441 aaataacgac ctgtatcaaa aaattcgtcg attgaatgtg tcaacacatg cccagtttga
    52501 tggatcagct gattttttgg ttcattcttc tcactttgtt cttcttcatg gacatgatga
    52561 tggtgatttt ctgctacttt agacgtgatt ttttctttca atacagcgtc tttttgaaaa
    52621 taggcaagcc agacaccaat cacaagggca acaaaaaagc tgcctatcac ccgccagctt
    52681 gccatctgcc aagaattgcc aaatgcgata aaagtggaaa aaatcacgat tggattgatg
    52741 atcggagcag tcagcataaa agcaaacgct gtgtgaactg gtacgccttt tttaacaaat
    52801 tgatgaacga tcggtacgat gccgcattca catgaaggaa agaaaaatcc taagatcgaa
    52861 ccagtaaaaa tagagaagat acgattttca ggaagccatc tcttcacacg ttctggggtc
    52921 aaaaatactt gtaaggcgcc tgagataaga cagcctaata atacgaaagg taatgcttca
    52981 ataacgatcg ataagaaaat cgtactcatc tgcaaaaccg aatttggaat aaaagaaaac
    53041 atgagtttcc tcctttttat ttctagttca ttcgctttgc aaatatacgc ttttattcaa
    53101 aaaaaacaag ttgctctgta aatttttaca caactcttat tttttaccaa agcacttcaa
    53161 ttgacttttt ctgttattcc cattaaatta aggtctcata catatcactt ctatcataaa
    53221 agggagaata aaaatgaaac aaaccactaa cttgactgaa gttcaagaca tactgcaaca
    53281 gtcatccgtt gccgtcattt atctttcgat gcctaattgc agtgtttgtc acgctgttcg
    53341 tccacgacta gaggaacttc tcacacatta tgatattccg gcacttcatt tggatgcatt
    53401 tgaaacacca gaagtagcta gtaaatttga agtgctgact gcgccagttg tcctgatttt
    53461 tcatcaagga aaagaagtct ttcggcaagc acggttcatc gactttaaaa aaatccgtta
    53521 tctactagat gaactgacag cagaagatga ttccctttct tatgaagaaa tcttccgaac
    53581 aaaataatcg ttgtccaaac agaaaaaagc gattgaacaa gtgaaagttt tgccttcatt
    53641 tgttcaatcg ctttttattt ttattctgct gtattttcgg aatgcgcatt tgcgtcagaa
    53701 tgcaagaaat agatcaaggt ttgcaattca ttcgtcaaat caacattttg gatcaataca
    53761 tctgacggag cattcaatcg agcagcggta aagttcaaga ttcctttgat tcctgcttcc
    53821 gttaactgat tgactacttc ttgtgctctt tcagcgggta tcgttaaaat tgctacttcg
    53881 atttgttgga tcttgatttg ttctgacata tcttccattg gataaacggg gataccgtct
    53941 acgatgcgcc caacgatttc ctcattcaca tcaaaagcac aactgatacg tatgctatta
    54001 ctttgatgga atttgtattt tagtaaagca cttcccaagt tccctacacc gatcagcgca
    54061 acatttgtca attgatcgtc gtttaatgtc tttgcaaaaa agtgcataag atcttctaca
    54121 tcataaccat acccacgttt tcctaattcg ccaaaataag aaaaatctcg acggatcgtt
    54181 gcactatcta cttgaacggc ttcacttaat tcagttgaag acactttttt ctttccagca
    54241 ttatttaaaa tccttaaata gcgataatac aaaggcagtc ttttagctgt cgcctttgga
    54301 ataatatgat ctttcacgaa atgacctcca cgtattgtct aattacatct ttgatttctc
    54361 catcatagca gtatttatag gaaaaaatca attccattgc tcagatattg tgaaatttta
    54421 ttctttattc atttatttat catttctgca aatctcgcag tataatggaa tttatggtag
    54481 actactaatt gaaaaatagt tttttatttg aggagaattc acaaagtaga aaagaggatt
    54541 ccatgatatt attacaagcc aatcagattg ctcgccattt tggtgcagaa gtcttatttg
    54601 aaaacataca tttagaaatc agtacaggcg ctcgtgtcgc tttagttggc agaaatggcg
    54661 ctggaaaatc gactttatta aagatcattg ctggaattga agcacctgat gaaggaaaga
    54721 tcgctaaaaa taaaacagcg actctcggat acctcgctca ggacacagga cttgattcca
    54781 atgaaacagt ttggaacgag atgctgaaag cttttgaaca agttagacaa atggaagagc
    54841 ggatgcgcga gctagagatt ttcattagcg aaggtacgcc agacacacct gcttatagtt
    54901 cttatttaaa agaatacgac cggctgcaac acgatttttc agatcgaaac ggctatggtt
    54961 atgaaaatga aattcgttcc gtattgcatg ggtttaaatt cgattcttca ttttatgatc
    55021 agaaaatcga tactttatca ggcggacagc gcacacgttt agctttagct cgcatgcttt
    55081 tgcaacaccc tgacattttg attctagatg aaccaacgaa ccatttagat atcgagacac
    55141 tttcctggct tgagaattat ctgcaaagct atactggtgc attattgatt gtttcccatg
    55201 accgttattt tttagataaa gtagtcaatg aagtctatga attaagcaga agaaaaatgc
    55261 gccattacaa aggtaactat tcgaaatatc tagatttgaa agcagaacag ttagcaagtg
    55321 aatggaaggc ttatgaaaag cagcaaacag aaatccataa attagaagac ttcgttgctc
    55381 ggaaccttgt tcgcgcctct accacaaaac gagcgcaaag ccgcagaaag acattagaaa
    55441 aaatggaccg gctggatcgt cctcaagggg atgaaaaaca agcaaacttt ctattcagta
    55501 tagaaaagcc ttctggaaat gtagtcttgc aaatcgaaga tgccgctatc ggatatgata
    55561 atgtcacctt atctgaacca atcaatctag atatccgtcg tcaagaagcg attgctctag
    55621 taggtccgaa tggtatcggg aaatcgacgt tgctgaaatc aatcattcac cagatccctt
    55681 ttatccgtgg aaaagaaacg ctagggacaa atgtcaccat cggctattac gatcaaggtc
    55741 aagctgatct gcatacaaac aagacgatcc tagcagaatt gtgggatgag catcctacca
    55801 ctccagaaaa agagatccga agtgctttag gtgctttctt attttctggc gaagatgtag
    55861 aaaaaccaat ccctctgcta agtggcggtg aaaaagcacg ggttgcttta gccaagttag
    55921 cgatgaacaa agaaaatttt ttgattttgg atgaaccaac aaaccattta gatattgaca
    55981 acaaagaagt attagaaaat gcattgatcg attatgacgg cacactgctt tttgtttccc
    56041 atgaccgata tttcatcaat cggatcgcga caaaagtcgt cgaactctct gaaaatggca
    56101 gcaaagtcta tctaggagac tatgattatt atttagagaa aaagcaggaa gaagaagaaa
    56161 tcgccgaatt gttggcacaa gatgagccag aatctgctcc tgctcccacg aacaaatctg
    56221 attattacca aagcaaagaa cagcaaaagc ttatccgtag ccttcaacga aaaattactc
    56281 aggttgaaga agaaatggcg cggatcgatg aatggatcga tcagttggaa caagaaatgg
    56341 tcgcgccaga aaacctggaa gatcacgtaa aactcaatga gctgaaccaa gatttagaag
    56401 ctgctagaca agatcaagaa acaaaattga cggaatggga agaactaagc ttggaattag
    56461 aagaatatga aaattaacga aaaaaccaaa acagaaacca ttcatgctgt tttggttttt
    56521 ctttttttat tttatcaaac aaaaattcca tatttacctt tttcaccaat aagaagacca
    56581 attactagtc attctcacta aagcttctaa ataatagtaa tcaccccaaa tacaaggtgt
    56641 atttacccca ttatttttgg gcttattata aacagactgt gttaaaaagc catcttcttc
    56701 ttccgttgta gcatatcttt ctttcaattg tcgcataatt ttccaaacag cagactggta
    56761 taagttcttt tctgttttgt ctaatagacc tgattctatt aattctaata atccacaaac
    56821 catgatcacc atactagatg tatctttttc ttctctgcta gaatcatcaa agatcaaatc
    56881 ccaataacaa atggtatctt ctggcaaccg attcataaaa taattggcta atattttgct
    56941 taaatcaaaa tatttttgtt ctttcaaata acgataactt aatgcaaaac cgtaaatccc
    57001 ccatgcttgg cctctagccc aacaggaatt atcactataa ccttgatgcg tacttccata
    57061 tcttggtttt ccatctttga catccatata aaatgtatga taagttgaac catcttctct
    57121 tactaaataa tctgctgcat tttgaatatg agcctgagca gcttttttat atttttgatt
    57181 tccagtttct tcactcgccc aatacaataa tggaagattc atgcaacaat ccatgatcat
    57241 tctaccttgt tgtgaaggat cactaggatc tccccaagct tgtataactc ctgccttctc
    57301 ccaaaaacgc tgaagtaatg tttctgcagc atcaattgaa gcttccttca tttttcgatt
    57361 tcccgttatt ttataatctg ctacggttga taaagaatac aaaaaaccaa gatcgtgatg
    57421 attagtgata atttgacagt caatcctgtg gataaaatct atatctgctt tttcagctgt
    57481 ttgttgaaat aaaggatcac ccgtcttctc aaataacaac caattaattc ctgtccaaaa
    57541 tccttctgtc caaccaatat tgtctcttaa tggataacgt ccttttatag gacactcgct
    57601 tgggaattga tactgactgt tactgatacg tttgattaac ctctccgtgt gtctgcgaca
    57661 acgctcgatc tcattattcc attctttttc cattaattct ttataacatt catttatcca
    57721 tttttctgga tgtattatct cttcaaacat cactttatca agcatttccc caccagcctt
    57781 tagcataatt ttagtctttt tttattgttt ttattttgga tagttagccc ggttgtccca
    57841 tcaaaatcaa ttttgggacg attgttccat acttctaaac tataatcccg atcttgatga
    57901 gcaaccactc ctgttccgag ccaatgggtt ccttttccaa atgtaccctc taatccagga
    57961 ataaaagtgt tttcccatgt catcaagttt gtattgggca aacccataat agctgtggat
    58021 tttcgtttaa tagtatcgtc acttaaacag ataatacctg aaaagccagc ttcactcacc
    58081 ctatagtttt ccttgtcttc ttctatgatt attccttctt tctcaggaga acattcaata
    58141 gcaaaccctg tctcatatag aacatattct gtatctaatt ctactttgtg tacgcgaatc
    58201 tgccagcctt caaaaggaat aagccaagtt ctgatttttg cctgtaaagt aggttcccat
    58261 gtagaggcaa gtacctcttt cttacataca atgtctcgta cattatttcg aacgatgaac
    58321 tgtccatagg ttttgatgct ctcattctta aaactggtcg tgatatatgt gtccgctcgc
    58381 tgaatcccta gcattgaatc cattgccatt tctgctttca attgattcgc tcgcggtatc
    58441 gaaaaaccaa attgactaga ataagcaaat tttaaatatt tttcattggt caatgtatgg
    58501 aaatttggcc ctaattgtcc cgcattcaaa aaaaatgtat gtccattatc atgttgtatg
    58561 agcaaattgg cttctgaaag aagtttagtt ccttcacgaa taggcatagg catttcttta
    58621 gccgtccaat actcatggtc ttcaggtagc gccaacaata aaaaaatctt attcagccat
    58681 aatggagata acgtactatt atagggttca gtcaatgtca attgagggta ggtataacca
    58741 atattcagga tacctttttc atcaaatatt tctttttgca tccaccatct tatattccga
    58801 ttgactaacc ccttgatttc acctaattta aaaggcaaaa gatcggccca caacatagct
    58861 gaccaaaagc ttgaaactgc aaaacgataa atcatgcttc gaccaaaagg cacatttgca
    58921 ccatcttccg caaaaaaatg aatatagtct ctagaaaaat caatagctcg gttcttatat
    58981 atctggctaa tgggcttttc tggttctagt acgctataaa tcaaaccata ataatgaaat
    59041 gcaaaaggat tataataatc ttggcgacct cttgaactgt ctcgatacca gccattttga
    59101 agataacaat tttctatatt atcaaatgct tctttcagtg ctgattcttt aactggataa
    59161 ccaaattttt ggataattgt tccgacaatt atcttaaaaa attgccaatt accatctgca
    59221 cattcatatt caaaaatttg cgagaaccaa tgaataatct ggcttttttc tcctgtatct
    59281 aattttttcc ataataattg ttcatgatga tataacgcta ataacattgc gggcatttct
    59341 accatacgct ggtctctttc atgtatttct ccccaataat cgggatggga aggatctgtt
    59401 ccagctttta ttcctgatag aattaatttc aaccatcgtt catctaattg gtcaattgcg
    59461 ggccccgctc cccataaaac ccgagagaat ccttccattc ctgcaatttt atttccatat
    59521 cctacccctt gatgtatata atcaatttgt gcgccacttg ctcgataaaa cggctggagt
    59581 ggttgattta tctttttaaa taagtcaaag taatcctgtc tggtccttaa tagtggtact
    59641 ggatgtttca ttgtattttc tcctcttttt actaccaaat agctaattcc gactgttcta
    59701 atcgaagtaa gccttcaata aaaaaataat cagaatagat cagtggcaca ttataagtca
    59761 gttctctatg gtatgcttct gctccgcctc caatgatccc atcttcatcc atattccaat
    59821 ttgcatagtg cttttctgtc ttttggagta tattgatagc agcttcatga tacatttttg
    59881 atcgtacaga ggaaacatat cctgctaatt ccagaagacc gcatgcagcg catactccag
    59941 cactggtatc aatattcgaa tcttttacag caaaatcaat gagaggaata taaccagttt
    60001 tttcgatttt ctgaataaaa tttactgcta tcttttctgc tatagctaga tagtacggat
    60061 tttttgtgta acgataactt aacgcgaatc catataaagc ccatgcattt cctctgctcc
    60121 aacaagaatt ctcattgtat ccttgcccgc caagtaaccg aatatatttc cctgattctg
    60181 catcaaattc tgcgatatgc ccggttgatc catctttcct cactagatac ttagctgttg
    60241 tatctgcatg ctgccgagca attttagaga acctcggatc accagtttcc ctcgaagccc
    60301 aatacagtaa tggtaaattc atcatactat caataatcat ccaaccaggt ttatggtcat
    60361 tccatgctac taaatagttc cctgaaatat tatagcgtcc agcaagtacc gtagctgcat
    60421 gtaaccctag ttgtcgacta tgtttgtttt gagactgttg ataatgtgca atagccgatg
    60481 gtaagaataa aaaacctaca tcatgatgaa cgtctgaaaa atggtacagg gcagattcta
    60541 ataattgttc ttgttgtatt gctgcctctt tgaacttttc tcgttttgtc ttgtgaaaga
    60601 gctgccataa aataccactc caaaaaccat tggtccacca gtcgattcct ctgtccttta
    60661 ttacgtctgt atattttccg ttgtaagaaa tatatggaat tttattcccc attctgtcta
    60721 attccgcatc tatcttttca gaagctacat tcaaaatttt tcttgaccat tccttcgtct
    60781 gttcattcat ggatatcccg ccattctttt aatttttatg aatgtggagt tgctcctaga
    60841 acgaactaga tggttaacat tcgttatttt ttttacttat ttgcagctcc aatgtcattc
    60901 tccttaaatt tagactgcgc ccacacataa atcaagacca ttgggatcac tgaagttgct
    60961 aaaattagca taattgcgcc ataattaatt ggctcacctg tactagaaac cgtcatattt
    61021 ttgataatta agggaaccgt atatttatct ttatctgaaa gcatgactaa tggaaataga
    61081 tattgattcc aacttcccat aaagataagt aaaccactag taataatcgt aggtgataaa
    61141 atcggtacag cgattttcgt aaaaatcacc cactcattgg caccatcgat tctggcagcc
    61201 tccatcagtg ctgtaggaaa ttgactgcta tattgtcgca tcataaacac tgaagttgta
    61261 ctggcaatcg aagggatgat cacacctgca taagtattcg ataatcctaa acgactcata
    61321 atgtaaaata aaggaatcaa tgtggtaaaa aaaggcacca tcctagatag cataactgta
    61381 ttgaacaaca gtttattccc cataaaacga tactttgcta atgcataacc cgccattgta
    61441 gaactggctg tagctaaaac tgtactgatt acagcaataa caatcgaatt ccaaataatc
    61501 aagggataat tatatctcgc catgatggct tgccagtttt ttaatagcat atccccaaac
    61561 ttgaaattga ttccgccact taaaatttct tgattacttt gcgttgaagc tacaatcata
    61621 tataaatatg gcatcaaaaa tattaaggca ccaaacacaa taatgacgta cgtaaaaatt
    61681 ctgctttgta tcttttgttt agtcattttt atcacctccg aatttaaatt gaatagccga
    61741 taatataaca gatacaaaca ccatcgtcca ggcaatagca gaggcttttc caaaatcaac
    61801 catttcaaaa cttgttttat ataaattgac tcctacgacc aaagctgaat tttctggtcc
    61861 attggaagtc ccaaagaata tatttgggat attgaaatta cccaagccat tgatagtggc
    61921 taaaactgtg gccattaaaa tgattggctt tagcatgggg atcgttaata aaaagaattg
    61981 ccgaaatttc gatgctccat ctatttcagc actttcgtat atctctttag aaatcccttg
    62041 aagaccagct aaaaataaaa tagtgttata tcctacacta agccaaatca tcgtgatgat
    62101 cattgatatt cgtatccaaa aaggatttgt taaccactgt acaccgttaa ttcctagcgc
    62161 attcaaaaat ccattgaata acccagtcgg attgaaaaaa gtcatgaata cggaagctac
    62221 agccaccgtt gatgtaatgg ttggaatata atagacagtt ctaaaaaatc cttttccttt
    62281 taactgtgct gaattcaata aaacagcaaa gtaaatagct aatagcatcg ttattggaat
    62341 tgatcctgcc atgataatca aaacattcgt gtaagattta ataaacaatg gatctcggaa
    62401 gatagctaga taattgtcaa atccaacaaa ttcaaatgag tagccaattt tcataaaact
    62461 aaaagcaaac gagataatga tgggaatcaa aatcgtcaca ataaagaaaa taacaaaagg
    62521 tgtgaccaat ccataagcac tttttttatg agacgtatct gttgcttttt tcttgctgtt
    62581 ctttattgtc ttgcttggta acgaagattg catcatcgtt aagtcctcct aatatttttt
    62641 aatcaccagt taattttacg ccgtacttat gagcaaaatt ttctgcttct tttagatatg
    62701 aattttcaaa atcacctgtt tgccaatagt tatatgcagc ggtagtcaaa taagacgtag
    62761 catctgaata agtggctggt aaaacagtat ttgatgtatt ttcattgatt ttattcaata
    62821 gttcatagta tttttgtcct ccttagtagt caaacttttt ctcagctgct tctgtttgat
    62881 aggccaatga gttagatgta gccacgccca gctccagtgc gttggctaag cattcttcat
    62941 ctgtcagcat aaatgtaaga aattgttgtg ccacttgtgg atttttggca tctttaggga
    63001 cataaaaact tgatcctcct gatactgcac cttttcctgg attttctttt gaaaaaggaa
    63061 tcagtggagc catgcgccat ttgtcagatg catcaggaaa attcaaagac atattcgtag
    63121 cataccagcc gccagcaaca aacattgcag attcttgaaa tgctttctca gcatcttgtg
    63181 caccgtagaa atgtacaata tctgagtcga tcatttcttt gattaacttt gcagcatgtt
    63241 tcgcttcttt agtattcaga cggatatttc cttcttcatc aagcaaagat tgattctgct
    63301 gggctagcat gttgataaac aattcttggt ccccagattc tggcaaggca attccaaaac
    63361 taccagtttt ttcttttaat gcttttgcca cctggatata ttcttcccaa gaactgattt
    63421 cttcaaaatc tacacctatt tcagcaaatt tttttggttg ataataacaa agtgctgggg
    63481 taaaatcact agcccaagga ataatcgttt cattactcgt ttgttgacgc aaaatattca
    63541 atttttgatc ataaaactga tcgccatatt tgtcataaaa tccatattca tcagcactat
    63601 aaaaagcatc ttgaaatttt tccagcacac ctgctgctga agtgtctgcc atggagataa
    63661 tatccggcat atcttcgtgt gttaccaatt ttggggtgat catttgtact gttgctgttc
    63721 ccgaagctac attcacaatt tttaagtcaa tatttgctcc agttttgcgg ttatagattt
    63781 ttgcagcatt ttcaacatag tttgtcagtt tgccgtttgc gacatatact tctaatgtag
    63841 tggctttttt tatcattgga tctgcgatgt ttgctgttac ttcttcgtta gtttttccac
    63901 atgcacttaa gctgaataat agggtaatgt ttagcaaagc tatcaccaat ttgtatcttt
    63961 ttttcatgtc tatcccttct ttcttttcaa gttcttatat aaaacgcttt cacttatgta
    64021 tattaacgga attagtaaca caaatattta tataaaaaaa tattttactt gtcgttttgg
    64081 cttttcattt ttgttataat agtcattaat tataaataga aagcttttta tataaaaaga
    64141 gaaaggaaag tggttctttt gttaacaaac aaccaatcct ccaatcttgt caaaaaaaca
    64201 ctaacctatt ccatagatac ccatcttcat ttatctgctg ctccctattt tcgactacta
    64261 ataaatgaaa gcgctaattt atatgctgaa tttgcacata aatctataga actagataat
    64321 ccttcccttt tattcattga taaacagcaa gaagtccaaa tcttttctac tcaaaaggaa
    64381 acacaaactt ttatcattat ccagttttat tttgatgagc aattattagc acatattacg
    64441 ggacaatctt tttctataga tcaagaaata acatctatca ttacttttct gaaaaatgaa
    64501 cagttcaaaa ttgattatct aaaacatagt aagccagcta tttcctatga tcaggaaatc
    64561 aattcttttt tcatactatg ccaacagatg agcattcatt tgctttcctt attagttact
    64621 tattgtctgc aaaaaattca attgtcttcc ttaccaaggc attatcaaca ggaacttgct
    64681 ttattgacaa taccttcaaa tgagaaagtc attcctaaaa aaaagcatat tctttattca
    64741 gatgaattag ttgatccaat catacgatat ttagaagaac atctttcaga aaattttttg
    64801 cttgaacaat tagcccaaat tttttttatc agtccagcca gcttaaaaaa acattttaga
    64861 aaagtgaatg gaaaaagtgt tattagctat tttaaagaac taaaaatgga aaaagcaaaa
    64921 cgtctcgtgc tagaaaatga attaacctat acagaaattg cagatatatt aggatttcat
    64981 tcgatccatc atttttcttc agcttttaaa aaatatacag ggttatcccc ttcaaagtat
    65041 tatctatcct taaaatagaa aaaaattttt aggttttatc cacaaattat ttctctatat
    65101 tttctgtcta ttcaaaataa acaataattt tccggcacaa ttatttgctg ttttttacca
    65161 taacatagta cgatcaacgt agaaaaggag atgtttttat gaaagttgtt gtcattggcg
    65221 gtgtagctgg cggtccttca tttgccactc gtttccgtcg attgaatgaa gcgcacgaaa
    65281 tcattatcta tgaacgcgga gaaaatattt cttatgcaag ttgtgctttg ccttattatt
    65341 taggaggtgt gatcactgac cgtgactcgc tgatcgaacg tacaccagaa atattgaaaa
    65401 caaaaaacaa catcgatgtc tttactaaac acgaagtaac agcaatcgat ccttctacta
    65461 agcgattaac agttaaagac ctatccacaa atgaagaaat aaaaacagat tacgataagt
    65521 tgatcatctc ttctggtgct agaccagatt atccggatat tcccggagtt tttgaagcag
    65581 aaaacggctt tgtcctccgt agtgtgacgg atgcggatcg aatcaaatcg ttccttgaag
    65641 aaaaaaaacc acaacatgtc gtcattcttg gtgcaggtgt tatgggtctg gaattagctg
    65701 agaatttcaa gcatcgcggc ttagacgtga ctttaatcga tcaattgcca caagtcgctt
    65761 tcccttatga tccagaaatt gctaatttag tttatgacaa attgctgaaa gaaggattag
    65821 ccgttcattt agaaacaaga gttactgaga tccgtgataa aggtcgagaa atagtattat
    65881 cagatggctc cgtcctttct gctgatatgc taatttttgc tgttggtgtt tctccgaaga
    65941 atgaagtggt gaaagcaacc ggcatacaat tatcagatac aggtcagatc attgttgatg
    66001 accagttaca aaccaatctg ccggacatct atgcgattgg cgatattatc gaaacgacta
    66061 gtgtagtgac tggtcagccg atccaaagta tgctttccag tgcggccaat cgtcaaggac
    66121 atatgctggc agatatttta aatggtacgc ctatgcgcta tcgcggatat attggtgcag
    66181 gtgtcgcaaa aatctttgat catacagcaa gttatgcggg aatgacagaa catgaattaa
    66241 aagcatcagg cataacaaat tataaaactg tttttatcac tccctttgac catgcctatt
    66301 tctatccaga agctacaaga ttaaatctaa agctgatttt tgatgcagat agcggtcgta
    66361 ttttaggtgg acaagcattt ggagaaaaag gtgtcgataa acggatggga gaactttctg
    66421 tagcaatcac cggaaacttg acagtctttg atttgcctga tttggagttg ccttactctc
    66481 caccgtattc tactacccgt gacccgttga atatagctgg ttatgtcgca atcaatcaaa
    66541 tgacgaatat cgtagaaacg atcaaagcaa gtgatatacc cgaaaacgat ttgaaagaag
    66601 cgttcttttt agatatacgt gaacctaata aagcaccttc tggcagtatc tcggcaacaa
    66661 aaaatattcc aatgaatgag ttacgagatc gaatcaatga aatcccaaaa gataaaaaag
    66721 tttacattac tttcagaaga ggattgaata cttatacttc tgcccgaatc ttggcaggtt
    66781 tgggtatcaa agcgattttg attgaagaat aaaaaaacga ccgcggtggg tagccgcggt
    66841 ctaggagtta tttttacttg aggagtaaaa atgaaaaagt atatagggtt gttggttggt
    66901 atgtatatag aatagaagat aaatgtgaag aaattgtgca ttatttcttc acatttatta
    66961 ggttatagtt taagaaagtt taaacattgc gcaatttaat tattttagct gtttcttttc
    67021 ataaaaaaac atgttgtgac tctgagacaa atcatagtcc atagtgatgt ctctagagta
    67081 actacgccta atattacgag gcatcatatt aatctatcag cactagtacc taaactagca
    67141 tccctttcga atattttttc ttatataata aagtttgctt tcactcctct aatctcacca
    67201 aatcgactgg cttgcgttgt gtgatactag gaactgattg gtttagaacg acttttctat
    67261 tgtaatcata tttttcgcca tcctcgttgt cttctaatcc ttcaatgaat gatccctaat
    67321 gtgtgtatta aataatttaa tttttttgtt cctatttatt taa
//
LOCUS       DAIGQM010000006        62158 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.006, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000006 DAIGQM010000000
VERSION     DAIGQM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.006"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(85..2238)
                     /locus_tag="NOA48_000334"
     CDS             complement(85..2238)
                     /locus_tag="NOA48_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCI0788634.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2633..3481)
                     /locus_tag="NOA48_000335"
     CDS             complement(2633..3481)
                     /locus_tag="NOA48_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0788635.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOA48_000336"
     CDS             complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOA48_000336"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCI0788636.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5982..6161)
                     /locus_tag="NOA48_000337"
     CDS             complement(5982..6161)
                     /locus_tag="NOA48_000337"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCI0788637.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOA48_000338"
     CDS             complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOA48_000338"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0788638.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8309..10588
                     /locus_tag="NOA48_000339"
     CDS             8309..10588
                     /locus_tag="NOA48_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0788639.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10681..11328)
                     /locus_tag="NOA48_000340"
     CDS             complement(10681..11328)
                     /locus_tag="NOA48_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788640.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11507..12226)
                     /locus_tag="NOA48_000341"
     CDS             complement(11507..12226)
                     /locus_tag="NOA48_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0788641.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12357..13508)
                     /locus_tag="NOA48_000342"
     CDS             complement(12357..13508)
                     /locus_tag="NOA48_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCI0788642.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13725..14465)
                     /locus_tag="NOA48_000343"
     CDS             complement(13725..14465)
                     /locus_tag="NOA48_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0788643.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOA48_000344"
     CDS             complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOA48_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCI0788644.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOA48_000345"
     CDS             complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOA48_000345"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCI0788645.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15426..16076)
                     /locus_tag="NOA48_000346"
     CDS             complement(15426..16076)
                     /locus_tag="NOA48_000346"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCI0788646.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOA48_000347"
     CDS             complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOA48_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCI0788647.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOA48_000348"
     CDS             complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOA48_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCI0788648.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17519..18046)
                     /locus_tag="NOA48_000349"
     CDS             complement(17519..18046)
                     /locus_tag="NOA48_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCI0788649.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18226..19011)
                     /locus_tag="NOA48_000350"
     CDS             complement(18226..19011)
                     /locus_tag="NOA48_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCI0788650.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19004..19873)
                     /locus_tag="NOA48_000351"
     CDS             complement(19004..19873)
                     /locus_tag="NOA48_000351"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCI0788651.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19874..21253)
                     /locus_tag="NOA48_000352"
     CDS             complement(19874..21253)
                     /locus_tag="NOA48_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCI0788652.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOA48_000353"
     CDS             complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOA48_000353"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0788653.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVAPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOA48_000354"
     CDS             complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOA48_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCI0788654.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOA48_000355"
     CDS             complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOA48_000355"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCI0788655.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOA48_000356"
     CDS             complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOA48_000356"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCI0788656.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOA48_000357"
     CDS             complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOA48_000357"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0788657.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25211..25435)
                     /locus_tag="NOA48_000358"
     CDS             complement(25211..25435)
                     /locus_tag="NOA48_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0788658.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25488..26450)
                     /locus_tag="NOA48_000359"
     CDS             complement(25488..26450)
                     /locus_tag="NOA48_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCI0788659.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26460..26900)
                     /locus_tag="NOA48_000360"
     CDS             complement(26460..26900)
                     /locus_tag="NOA48_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0788660.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27206..28171
                     /locus_tag="NOA48_000361"
     CDS             27206..28171
                     /locus_tag="NOA48_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0788661.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28228..28458)
                     /locus_tag="NOA48_000362"
     CDS             complement(28228..28458)
                     /locus_tag="NOA48_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCI0788662.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28544..29431)
                     /locus_tag="NOA48_000363"
     CDS             complement(28544..29431)
                     /locus_tag="NOA48_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCI0788663.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29520..30743)
                     /locus_tag="NOA48_000364"
     CDS             complement(29520..30743)
                     /locus_tag="NOA48_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0788664.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30760..31806)
                     /locus_tag="NOA48_000365"
     CDS             complement(30760..31806)
                     /locus_tag="NOA48_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0788665.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOA48_000366"
     CDS             complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOA48_000366"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCI0788666.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(33697..33963)
                     /locus_tag="NOA48_000367"
     CDS             complement(33697..33963)
                     /locus_tag="NOA48_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCI0788667.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34442..36676
                     /locus_tag="NOA48_000368"
     CDS             34442..36676
                     /locus_tag="NOA48_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0788668.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36824..37144
                     /locus_tag="NOA48_000369"
     CDS             36824..37144
                     /locus_tag="NOA48_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0788669.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37349..37573)
                     /locus_tag="NOA48_000370"
     CDS             complement(37349..37573)
                     /locus_tag="NOA48_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCI0788670.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDLKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37771..39351)
                     /locus_tag="NOA48_000371"
     CDS             complement(37771..39351)
                     /locus_tag="NOA48_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCI0788671.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39752..41128)
                     /locus_tag="NOA48_000372"
     CDS             complement(39752..41128)
                     /locus_tag="NOA48_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0788672.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41256..42374)
                     /locus_tag="NOA48_000373"
     CDS             complement(41256..42374)
                     /locus_tag="NOA48_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0788673.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42516..42796
                     /locus_tag="NOA48_000374"
                     /pseudo
     CDS             42516..42796
                     /locus_tag="NOA48_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(42874..43407)
                     /locus_tag="NOA48_000375"
     CDS             complement(42874..43407)
                     /locus_tag="NOA48_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCI0788674.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOA48_000376"
     CDS             complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOA48_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCI0788675.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOA48_000377"
     CDS             complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOA48_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCI0788676.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45576..46958
                     /gene="rlmD"
                     /locus_tag="NOA48_000378"
     CDS             45576..46958
                     /gene="rlmD"
                     /locus_tag="NOA48_000378"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0788677.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47132..47710)
                     /locus_tag="NOA48_000379"
     CDS             complement(47132..47710)
                     /locus_tag="NOA48_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCI0788678.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48032..48502
                     /locus_tag="NOA48_000380"
     CDS             48032..48502
                     /locus_tag="NOA48_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCI0788679.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48610..49836)
                     /locus_tag="NOA48_000381"
     CDS             complement(48610..49836)
                     /locus_tag="NOA48_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0788680.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50590..50790)
                     /locus_tag="NOA48_000382"
     CDS             complement(50590..50790)
                     /locus_tag="NOA48_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0788681.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(50924..51532)
                     /locus_tag="NOA48_000383"
     CDS             complement(50924..51532)
                     /locus_tag="NOA48_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCI0788682.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51617..52087)
                     /locus_tag="NOA48_000384"
     CDS             complement(51617..52087)
                     /locus_tag="NOA48_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCI0788683.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52135..53049)
                     /locus_tag="NOA48_000385"
     CDS             complement(52135..53049)
                     /locus_tag="NOA48_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0788684.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53195..53998
                     /locus_tag="NOA48_000386"
     CDS             53195..53998
                     /locus_tag="NOA48_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCI0788685.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54176..55123
                     /locus_tag="NOA48_000387"
     CDS             54176..55123
                     /locus_tag="NOA48_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCI0788686.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(55191..55484)
                     /locus_tag="NOA48_000388"
     CDS             complement(55191..55484)
                     /locus_tag="NOA48_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCI0788687.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(55512..56177)
                     /locus_tag="NOA48_000389"
     CDS             complement(55512..56177)
                     /locus_tag="NOA48_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCI0788688.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(56317..56949)
                     /locus_tag="NOA48_000390"
     CDS             complement(56317..56949)
                     /locus_tag="NOA48_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788689.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(56956..58023)
                     /locus_tag="NOA48_000391"
     CDS             complement(56956..58023)
                     /locus_tag="NOA48_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0788690.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(58020..58751)
                     /locus_tag="NOA48_000392"
     CDS             complement(58020..58751)
                     /locus_tag="NOA48_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCI0788691.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(58919..59398)
                     /gene="greA"
                     /locus_tag="NOA48_000393"
     CDS             complement(58919..59398)
                     /gene="greA"
                     /locus_tag="NOA48_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCI0788692.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(59534..60709)
                     /gene="mltG"
                     /locus_tag="NOA48_000394"
     CDS             complement(59534..60709)
                     /gene="mltG"
                     /locus_tag="NOA48_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCI0788693.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            60874..62034
                     /locus_tag="NOA48_000395"
     CDS             60874..62034
                     /locus_tag="NOA48_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0788694.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT        17928 a        13125 c        10479 g        20626 t
ORIGIN      
        1 aaatttaagc aaaaatgtga gaagctattt tcacaaaatt tttcttcata ctcgaaacta
       61 agcggctttt tcacgacctc ttttttattt tgccatgaac atatcataat acgcgtccat
      121 tatttcttta gcaatcgtca agtttatgtg gtcttgttcg tctaataagt tcggcaagac
      181 aacactgatg gcaatttccg gattgtctgt tggtccgtat gccacgatat tactattgac
      241 tgtcgcaata tctggatgac cttccgcaac cgtttctgca gtccctgttt ttgcggaaag
      301 gtccattttc gcactggcta atggtttggc tgttgtgtaa ggatcggtac catggacaac
      361 ttggtggaat ccttcacgga ggatcgccat attttctgca gaaatattga ccgtattttc
      421 tactgttgtg ccaatttctt tcttcacttc acccaagttt ccattttcgt cattgccata
      481 gatcgctttg actaggtgcg gctgtactcg tttcccgcca ttagcgactg ttgaagcata
      541 ttgagctaat tggattggtg tatatgtgtc aaactgtcca aatgccaaat cggtaaagtt
      601 acctggagca taccattctt tgccattatc cgcattgaac ttcttcatat aatcaacaga
      661 acgtgagatc ccaggagatt cattcggcaa atcgatccca gtcgttgtac caagaccaaa
      721 ctctttgaaa gagtctctca attgctgata agctttagct tcttcatcta aactaggtag
      781 tcccattcca ggtgtatagt ctagtcctaa catctttaac gccactttga tcatatacgt
      841 attagaagac aattccgatg ctttgactgc atcaagagca acttgtccgc ttcgattaaa
      901 gacagagctt ttttctgaag caccttgcag acgaatcggc tcatcaatca aaacttgatt
      961 tccgctgatc gcgttacttg cccagcctgc tgtcaaagta ccagccttga ctacagaccc
     1021 tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg gtgatttctt tggaaccttg
     1081 ttcatgactg aaaccagtca ttgctagcac ttctcctgtc tgaggattca tagccactgc
     1141 ataagcacca ggcgaatact gtgctttgcc gttgttgatc aatgtttgat aattcctttt
     1201 caaaatttct tctacttttg attggaattc tgcattcata gataacatta aattagaacc
     1261 tttttcccca gagaagattt ctttttgatt cgaaacattt ccttcattat caagggaaac
     1321 ttcatattgg gttttggttc cttgcaggac atcttcatat tgtttttcca aataactttg
     1381 tcctacacgg tcattccgag aataaccttt tgctaggtat ttctctgctt catctgctgg
     1441 aagtccttgc ttttcagtcg tcacactgcc aagaatactt ttcagtgaac ttgctgcatt
     1501 atattctcgt gtccagtctg tgccagtcga aactcctgga agttcagaag cgcgttctgc
     1561 cacaacagct aactcttgat cagtaacacc agagtttttg atatagacag tgtttaattc
     1621 atatgcacta ttcatccgtt taaagatggt agcaattttt aattgctcct cgtttaaatt
     1681 aatctcatca gctgtgactt tattgaccat cgcactatat tgttcgctgt tccctaattg
     1741 cttttctttt gccgaaagtc tttttgtggc ttctttcaaa tgtttgggat cagccagcca
     1801 aaaatctttt ttatctctat ctgtcagatt ttcatctacc ggaacatcga tcagcgagtt
     1861 cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact tgtgttcctc tcgtatatgt
     1921 gatggcctga ttcgctttat tcgtaactaa agcttttcct gtggagtcgt agatcattcc
     1981 gcgaggagta ctttcttgga ccgtaatcgt agaagtagac ttcactcgcg cctccatctc
     2041 ttcgccgttc acgatctgca aataacccaa tctagcaatc aacgcaacaa ataacgtaaa
     2101 tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg gaccggcgaa acgttttgtt
     2161 cttaggttct tgtgcacctt ttcttatttt ttctaaccaa gaagtattta atattttttt
     2221 cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct tcattgtacc
     2281 caaaaacttc ttaataaaca agaagtattt aatatttttt tcataaaatc tttcatcatt
     2341 tcctatcctt ccgcctattt acattcatgc ttcattgtac ccaaaaactt cttaataaaa
     2401 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
     2461 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
     2521 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
     2581 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
     2641 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
     2701 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
     2761 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
     2821 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
     2881 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
     2941 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
     3001 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
     3061 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
     3121 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
     3181 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
     3241 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
     3301 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
     3361 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     3421 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     3481 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     3541 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     3601 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     3661 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     3721 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     3781 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     3841 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     3901 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     3961 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     4021 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     4081 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     4141 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     4201 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     4261 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     4321 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     4381 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     4441 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     4501 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     4561 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     4621 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     4681 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     4741 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     4801 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     4861 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     4921 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     4981 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     5041 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     5101 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     5161 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     5221 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     5281 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     5341 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     5401 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     5461 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     5521 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     5581 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     5641 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     5701 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     5761 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     5821 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     5881 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     5941 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     6001 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     6061 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     6121 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     6181 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     6241 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     6301 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     6361 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     6421 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     6481 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     6541 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     6601 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     6661 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     6721 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     6781 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     6841 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     6901 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     6961 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     7021 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     7081 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     7141 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     7201 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     7261 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     7321 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     7381 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     7441 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     7501 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     7561 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     7621 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     7681 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     7741 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     7801 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     7861 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     7921 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     7981 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     8041 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     8101 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     8161 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     8221 ttcgattcat cagttaaaga gtaccttttt tcgaaaaact atgctatact tttaattcgt
     8281 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     8341 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     8401 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     8461 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     8521 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     8581 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     8641 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     8701 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     8761 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     8821 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     8881 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     8941 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     9001 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     9061 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     9121 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     9181 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     9241 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     9301 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     9361 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     9421 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     9481 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     9541 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     9601 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     9661 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     9721 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     9781 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     9841 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     9901 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     9961 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
    10021 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
    10081 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
    10141 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
    10201 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
    10261 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
    10321 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
    10381 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
    10441 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
    10501 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
    10561 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
    10621 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
    10681 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
    10741 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
    10801 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
    10861 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
    10921 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
    10981 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
    11041 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
    11101 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
    11161 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
    11221 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
    11281 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
    11341 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
    11401 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
    11461 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
    11521 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
    11581 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
    11641 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
    11701 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
    11761 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
    11821 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
    11881 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
    11941 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
    12001 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
    12061 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
    12121 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
    12181 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
    12241 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
    12301 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
    12361 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    12421 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    12481 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    12541 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    12601 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    12661 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    12721 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    12781 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    12841 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    12901 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    12961 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    13021 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    13081 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    13141 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    13201 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    13261 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    13321 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    13381 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    13441 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    13501 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    13561 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    13621 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    13681 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    13741 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    13801 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    13861 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    13921 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    13981 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    14041 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    14101 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    14161 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    14221 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    14281 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    14341 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    14401 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    14461 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    14521 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    14581 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    14641 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    14701 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    14761 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    14821 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    14881 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    14941 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    15001 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    15061 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    15121 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    15181 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    15241 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    15301 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    15361 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    15421 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    15481 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    15541 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    15601 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    15661 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    15721 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    15781 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    15841 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    15901 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    15961 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    16021 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    16081 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    16141 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    16201 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    16261 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    16321 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    16381 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    16441 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    16501 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    16561 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    16621 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    16681 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    16741 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    16801 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    16861 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    16921 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    16981 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    17041 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    17101 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    17161 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    17221 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    17281 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    17341 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    17401 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    17461 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    17521 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    17581 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    17641 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    17701 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    17761 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    17821 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    17881 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    17941 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    18001 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    18061 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    18121 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    18181 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    18241 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    18301 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    18361 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    18421 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    18481 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    18541 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    18601 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    18661 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    18721 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    18781 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    18841 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    18901 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    18961 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    19021 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    19081 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    19141 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    19201 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    19261 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    19321 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    19381 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    19441 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    19501 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    19561 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    19621 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    19681 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    19741 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    19801 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    19861 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    19921 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    19981 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    20041 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    20101 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    20161 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    20221 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    20281 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    20341 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    20401 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    20461 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    20521 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    20581 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    20641 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    20701 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    20761 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    20821 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    20881 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    20941 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    21001 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    21061 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    21121 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    21181 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    21241 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    21301 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    21361 tcaacttcaa ggtataaggt atctcccggt gcaactttct tacggaattt tgctttgtcc
    21421 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    21481 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    21541 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    21601 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    21661 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    21721 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    21781 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    21841 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    21901 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    21961 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    22021 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    22081 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    22141 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    22201 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    22261 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    22321 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    22381 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    22441 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    22501 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    22561 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    22621 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    22681 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    22741 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    22801 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    22861 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    22921 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    22981 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    23041 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    23101 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    23161 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    23221 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    23281 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    23341 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    23401 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    23461 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    23521 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    23581 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    23641 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    23701 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    23761 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    23821 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    23881 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    23941 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    24001 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    24061 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    24121 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    24181 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    24241 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    24301 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    24361 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    24421 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    24481 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    24541 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    24601 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    24661 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    24721 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    24781 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    24841 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    24901 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    24961 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    25021 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    25081 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    25141 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    25201 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    25261 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    25321 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    25381 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    25441 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    25501 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    25561 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    25621 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    25681 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    25741 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    25801 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    25861 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    25921 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    25981 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    26041 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    26101 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    26161 ccttgtactt gtgctgctac agatggcgtc gtgtaatcgg gcgacattgt tgctactaaa
    26221 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    26281 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    26341 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    26401 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    26461 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    26521 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    26581 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    26641 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    26701 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    26761 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    26821 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    26881 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    26941 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    27001 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    27061 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    27121 aacagaacta tagaattcct taaaacttgt ccattatttc aaaatttgtt atagtctttt
    27181 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    27241 gccgggtgtc tatcttatga aagaccgtga tggtaaggtc atctatgttg gtaaagcaaa
    27301 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    27361 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    27421 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    27481 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    27541 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    27601 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    27661 gcgagcccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    27721 agggctgttt caaggccaaa ataaaaagct actaacttac ttgaaaaaaa gacaacaaca
    27781 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    27841 tacttatttt attagacgga tccaggaaca aaagcatttt ttaagaacac catcgctcac
    27901 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    27961 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    28021 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    28081 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    28141 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    28201 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    28261 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    28321 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    28381 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    28441 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    28501 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    28561 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    28621 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    28681 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    28741 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    28801 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    28861 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    28921 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    28981 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    29041 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    29101 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    29161 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    29221 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    29281 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    29341 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    29401 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    29461 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    29521 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    29581 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    29641 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    29701 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    29761 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    29821 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    29881 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    29941 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    30001 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    30061 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    30121 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    30181 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    30241 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    30301 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    30361 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    30421 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    30481 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    30541 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    30601 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    30661 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    30721 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    30781 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    30841 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    30901 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    30961 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    31021 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    31081 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    31141 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    31201 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    31261 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    31321 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    31381 gcgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggatactata
    31441 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    31501 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt
    31561 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    31621 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    31681 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    31741 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    31801 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    31861 acttaagccc tatttttatc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    31921 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    31981 attcatgaac aagttcaacg acttcttcca tcgtatcgca ttctttcaat gcacgatcag
    32041 caagttcagc cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag
    32101 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    32161 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    32221 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    32281 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    32341 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    32401 tgatgccgac ttggatcgta tcagatactt ccttgccttc actgatcaat ttttgttttt
    32461 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    32521 tgatacgtaa gttaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    32581 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    32641 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    32701 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    32761 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    32821 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    32881 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    32941 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    33001 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    33061 tagcagtaat ttcttttgta ccaacgattg ctggaatttc taaagaacgt gccatgatag
    33121 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    33181 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    33241 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacatcac
    33301 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    33361 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    33421 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    33481 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    33541 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    33601 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    33661 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    33721 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    33781 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    33841 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    33901 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    33961 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    34021 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    34081 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    34141 tttcatcctt ttcttcacat tttataacaa acgtgtttat tttctttttc ttgtcgcttt
    34201 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    34261 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    34321 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    34381 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    34441 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    34501 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    34561 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    34621 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    34681 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    34741 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    34801 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    34861 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    34921 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    34981 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    35041 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    35101 agttcacgaa atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    35161 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    35221 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    35281 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    35341 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    35401 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    35461 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    35521 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    35581 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    35641 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    35701 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    35761 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    35821 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    35881 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    35941 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    36001 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    36061 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    36121 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    36181 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    36241 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    36301 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    36361 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    36421 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    36481 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    36541 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    36601 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    36661 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    36721 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    36781 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    36841 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    36901 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctg aacataatga
    36961 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    37021 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    37081 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    37141 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg
    37201 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    37261 aaaattcacg aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa
    37321 acgcttctgt ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta
    37381 cttttctctt ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat
    37441 ggatgattga tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttaaatcta
    37501 ataatcgaca taatcgtaac atctcttctt ttttctgttt ttttctttca cgtatttgcc
    37561 attctgtttc catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt
    37621 atattttttt gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa
    37681 atccgtcacg gctctaaaca aaatatgaga gactgttttt gtttggctat tcttattact
    37741 tgatgcaggg cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattagg
    37801 atatttatcc gcaaaccagc gttctgcaaa ttggttctcg aataagaaca atggttggtc
    37861 gaaacggtca cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg
    37921 atcgatccag cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc
    37981 atttaacata cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata
    38041 ttcttccgtt agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat
    38101 tcctttgtgg aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc
    38161 tggagtaaat gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc
    38221 cccaatctga taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc
    38281 gacgttttct ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt
    38341 tgtacgttcc aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa
    38401 agcgattcgg tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga
    38461 aaattcttcc tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc
    38521 tggtgccaat tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga
    38581 accaaaaaat actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc
    38641 agcctctttg attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag
    38701 aggatgattt tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata
    38761 attttccgga cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc
    38821 tttacccata ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa
    38881 ttcttctaac aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa
    38941 tatcgggatg ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc
    39001 ttttgcacta tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc
    39061 ttcagaaaaa tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc
    39121 aaactgcata acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc
    39181 tgatttggca aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc
    39241 accaaacaat agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat
    39301 cgcaaaagtt ctgcgattgt ccacttgttg ctttaattct ggattattca taacctaact
    39361 ccatttcttc cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa
    39421 gaaagacaat ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta
    39481 aacggcgttc tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag
    39541 ctgtttttgc ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc
    39601 aactactaca actgaatcag tatagcatgg attcatcgaa tgaaaaagcc accaaaccat
    39661 aagagtcaaa tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca
    39721 agcaacacgt ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt
    39781 cttttctgaa gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa
    39841 aaatgacacg gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat
    39901 tatcgacatc aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca
    39961 aataaccagc catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga
    40021 actcatcaat cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa
    40081 gattctcaac ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt
    40141 ctagtgttgc taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct
    40201 gcgtcttttt catttcatat aacagatcat caataaagac cgtttcagga acgaataaag
    40261 gctcctgcat gattttcttg atatctaaat tatcaaaacc gaatttatgg gcagctttta
    40321 gtaaattctt tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga
    40381 ttcttgaata gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat
    40441 caatcataaa tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag
    40501 aaaaaacccc ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca
    40561 tataacgcat ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga
    40621 tacgcgccaa taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac
    40681 caatcaagcg tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa
    40741 tacgtttagg gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa
    40801 tgatatttgc aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg
    40861 ataaagtatt agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga
    40921 ttgtcgatag gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat
    40981 ctccttcatc agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg
    41041 aagctgctaa aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca
    41101 gcgactgact ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt
    41161 agtttacgat agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat
    41221 tttctttgca ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc
    41281 ttgttttcat tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg
    41341 cagattgcgt aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct
    41401 actagaagaa cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta
    41461 ggataaatga tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat
    41521 gcttttaccg gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt
    41581 cctaaatatg gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc
    41641 acaccaatta ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct
    41701 tgtccgctaa tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg
    41761 tttcttcttt tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc
    41821 aacatataga acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt
    41881 ccaacgatcg aacctaaact attggatact ccactaagga attgctgaat gattgtcccg
    41941 taagaaatgt ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat
    42001 tcggctacct cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc
    42061 aatgaggaaa tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct
    42121 gcaactaaaa ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc
    42181 aacagcttga caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca
    42241 aataacgtgg aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc
    42301 atgatcaatg cagctatgat caataattca agcgaccaaa acattagttt agactgtcta
    42361 agtttttcaa acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa
    42421 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
    42481 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
    42541 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
    42601 agggtatgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
    42661 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
    42721 aaatgaaatt acagcggatg gcgatccttt tgaagatgct ggcatgcctc atatttatat
    42781 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
    42841 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
    42901 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
    42961 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcggat aattcatcat
    43021 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
    43081 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
    43141 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
    43201 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
    43261 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
    43321 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
    43381 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
    43441 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
    43501 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
    43561 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
    43621 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
    43681 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
    43741 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
    43801 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
    43861 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
    43921 cgctccagaa tgattttgaa gagccgcact gatataataa acgtcttttg gctttgcttt
    43981 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
    44041 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
    44101 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
    44161 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
    44221 tactcgcatc acgttgccgt caaccgcggg ttctggaagt ccaaatgcga tacttgcaat
    44281 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
    44341 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
    44401 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
    44461 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
    44521 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
    44581 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
    44641 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
    44701 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
    44761 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
    44821 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagcc atcgcttgtt
    44881 ggatcacttc ttgagaaaaa cctttcgtca tcaatgtttg ttggattttt ctcaataatt
    44941 ctttttggct ttttccgcga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
    45001 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
    45061 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
    45121 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
    45181 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
    45241 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
    45301 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
    45361 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
    45421 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
    45481 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
    45541 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
    45601 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
    45661 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
    45721 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
    45781 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
    45841 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
    45901 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
    45961 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
    46021 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
    46081 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
    46141 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
    46201 tcggtgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
    46261 aaaaaaacgc aatgatctgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
    46321 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
    46381 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
    46441 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
    46501 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
    46561 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
    46621 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
    46681 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
    46741 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
    46801 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
    46861 gtaaaaagtt caagattgaa tatttacagt ctgtcgacat gtttcctcag actgcacgtt
    46921 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
    46981 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
    47041 accgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
    47101 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
    47161 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
    47221 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
    47281 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
    47341 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
    47401 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
    47461 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
    47521 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
    47581 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
    47641 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
    47701 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
    47761 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
    47821 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aaccaaatca
    47881 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
    47941 atcatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
    48001 taaactacta ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
    48061 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
    48121 cggagaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
    48181 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
    48241 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
    48301 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
    48361 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctac atcatcgcct
    48421 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
    48481 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
    48541 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
    48601 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
    48661 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
    48721 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
    48781 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
    48841 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
    48901 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
    48961 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
    49021 caactggtct tgtttgattg tttcaaacgc aggggtgtag ttcgtcgcta catcaagcat
    49081 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
    49141 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
    49201 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
    49261 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
    49321 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
    49381 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
    49441 ggccatttcg acaccaccaa atgcataggc atgatttaat ttatctaccg ttccataacc
    49501 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    49561 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    49621 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    49681 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    49741 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa caaatacccc
    49801 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    49861 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    49921 tttaaaaaac atttttgtgt aacgattact attttttaaa atttctcaaa attcttaact
    49981 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    50041 tcttttttta cgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    50101 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    50161 attatcattc gatttcacga aaatttcttc ctatgactgg tccttttgtt aaacccatct
    50221 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattt
    50281 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    50341 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    50401 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    50461 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaaa
    50521 tctaaaaact tcataaatag acaaaaagac acgactctct aagaagtcgt gtctttattc
    50581 aacaaattat tataatttag tcacttcagc agcttgaggt ccgcgtgcac cttcaacaat
    50641 cgtgaattct acttcttgac cttcttctag gctcttgaag ccgtctcctt gaattgctga
    50701 gaaatgaaca aatacgtcat ctccgccgtc tactgtaata aacccaaatc ctttttcatt
    50761 gttgaaccat ttaaccgttc cgtgttccat aaatgtatag cctccaaaaa agttcttgca
    50821 agtaaccttg caagaacatt atacccaatt tagaaaacgc tagcaagctt tcgctctttt
    50881 attttccaaa ttatttttaa gactgatatg acggaggaaa tggttatttt gctgcttcga
    50941 aacgtttgtt tacttcatcc caattaataa cattccagaa tgctgcaata taatctggtc
    51001 ggacattttt atatttcaaa taataagcat gttcccaaac gtccaaacct agaattggtg
    51061 tctttccttc catcaatgga gaatcttgat ttgcagtaga ggtaatagct aattttccat
    51121 tttccattac aagccaagcc catccagaac caaatcgtcc agcggctgct tttttgaatt
    51181 cttctttaaa agaagaaaaa tcaccaaaag cttcattaat cgcttctttt atttctcctg
    51241 taggttcgcc accagcattt ggtgccatga tttcccagaa aaatgaatgg ttagcatgtc
    51301 cgccaccatt gttacgtaca gctgtcttga tatctgttgg aatagcgtcc atatcagata
    51361 ataattcttc tattgttttt tcgcctaatt ctgggtattt ctcaattgct gcatttaaat
    51421 tcgtcacata agtattgtga tgcttatcat gatgcagatg catcgtttct tcgtcaatat
    51481 aaggttccaa tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc ataaaaaaat
    51541 tcctcctcaa tgttttcttt ataatgtcta cattacaaag agtaacaaag agaaggaaat
    51601 tcttcaattg ttatgcctag tcgtcttttt cactttgacc tacttcttct tcaaaaacct
    51661 cagtttcttt aaaaataaac aacttgctga aaatatagtt cgctaggata acaataattt
    51721 gagtgatgat tttcgccaca tactcattgc tgttcataac attgatcaac aataccattg
    51781 cccccatgtc caatccgtaa gaaaggatac ggtagaagaa gaacttaccg cattcaataa
    51841 gtgcatgtgt aaaattcggt gattttgaat ggaataccca aagtttgttc gttacaaaag
    51901 caaacaatac agaacaaaac cacgaaatag aattggataa ggccatactt aaatcaaaat
    51961 attggcgtgc gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca ccaaaaaaga
    52021 gatagactag tatctcccaa tatccttttg cttctaaata tccttttaac tgtcgatact
    52081 gcttcatgag ccaacctacc ttattaaaaa ttcttattta tcatactcta tatttcaata
    52141 actttcatct ttatttaaaa aaattaattt tttttgatcc tttgcctttg tctctgcttg
    52201 gatcgtcaca tgtgtaatac catattttaa ttttaataaa gaaattatac gaggatatat
    52261 cttttcaatc tcgcttagta gctgatcttc aaaatcaata tgtccgtcga aaataattat
    52321 cttttcgcta tactgccaaa tatggacatg atgaacattc tttaccccat cgattgcttc
    52381 aatttcttgt tccatttttt catagtcaat agcaggtgca ctttgtatca aaatagcggc
    52441 agcttttttg atcaccatta tcgcttctat caatatatat atcgaaatga tcagtgtaat
    52501 aactggatcg atccagtaga tatcgaaaaa acggatcaaa attgctccga taatcacact
    52561 taccgaagac agtgtatcac ttaacaaatg caaataacta gattttatat tcaaactttc
    52621 atctgcttct tgtcgtaata ataatactga gaacaaattc gctagcaatc caataactgc
    52681 tactgttagc atcaaatgac tatttatctt ttctggtgaa gtgaaccgct tgaatgcttc
    52741 aacggttaaa aacaaggata atatgatcaa tatgaatgag ttgatgaaag cactcaatat
    52801 ttctaaacgc tggtagccat acgtacgttt tttatttgct tcttttcggg ccattttttg
    52861 tgccccgtaa gaaaaaataa ttgccaatgt atcactaagg ttatggaaag catctgaaac
    52921 aagagacaaa ctccctgaca taatccctcc aataaattct gataaagtga tcaccgcatt
    52981 caaaaccact actccaaata gtttttttga tgatctctgt ggctgtgtag gcactattcc
    53041 ttcctccatt ttatttatat tggatagtct ttagacaaga ataacatttt tttgatattt
    53101 caccaatcat tcagatgttt ccctaaagca cttgtatttc acttgatact tcgctagaat
    53161 tgcaagtgat gacactacta gatgaggagt acttatgaca acaaaacaat taattatcag
    53221 ttcctttata cgattcaaag acctaaagga ggcgagaaat gtcccatttt ggaaagccat
    53281 tgtctatctt ttagttttga gtataattat ggctttgcca atctcttttc aagtttttca
    53341 agtcttaaat aacattcaat tggatgggca aaagattgct actcgcattc ctgattttac
    53401 aatccaaaac gggcagcttc aaaccgaaga aaaagaagga ttcatttacc aaacaaactc
    53461 cattatcttc acatttgatc cagagggaaa acgaacagaa caggacatct ctactgattt
    53521 gatggggaat tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag ctcttcctaa
    53581 tacaggcacg acttctgctt tgttgaacaa taaccaatta gaacttccct acaccaatga
    53641 atctttaaaa aacttaacag gtaagcagct ccgttctttt ttaagtgaag catctatacc
    53701 actttggata aaagtcctga catttatatt ttctatttat cctagttttc tgaatctgct
    53761 gatcactttg ctatttacca acattgctgc ttttctctat gcacgctttc gactaacaaa
    53821 agctactttt cttgattgtt taaaaacatt gatctattca atttcattgc ctactataat
    53881 tgcaacaatc ttgatggtct ttcttccttc ttttgacact agcgccttca ttgcttttgc
    53941 aggaatcttt atttttgctc aagctgtcaa aggatgggca aaaatatcga tcaattaaga
    54001 aataaagaca actcgttatt tctacttaaa tagacccttt tagaggttgt gacatttttt
    54061 tgtcacagcc ccttttttat ttgaaaaata tttctttctc aaaaaacaag caaggcgctt
    54121 caaagttctt cttgtatgcg ctacacttag agtaaagaaa ggcgggaaat taactatgtc
    54181 agaaagaatc atttatgcag atcgtccatt tcgtgatgaa tttatcgaag aaatccatac
    54241 tatagcgcct ggttatatct ttaaaacaga attacaacca gaggatctac aaaatgtaga
    54301 gatcagtttg ggctggaact cagactacca agaaaaacta ttagcctctt ctaccttgaa
    54361 atgggtccaa tctatctcag ctggtgttga tcagctaccc cttgagactt tttcaaagaa
    54421 acatatttta ctttcaaatg gtagtggcat ccacagtgaa tcgattacgg agcatgtctt
    54481 aggaatcatc cttgggtatt ctcgtggtct ttttcaagca caaaaggcac agagtgacat
    54541 gaaatggtta ggttcatcgg tccattacca atctatccaa gggaaaaaaa tactaatcat
    54601 tggaactggc catattggaa aaatgattgc aaaaaaatgc aaagcattag acatgaactg
    54661 ctatggaatc aatacatccg gtcatccagc agaaggaatg gaaaagactt tttctttaaa
    54721 tcaactaaag gaagttcttc ctgaagtaga tttcgtagtc aatatcttac ctctaacgga
    54781 ggaaacaact gggctctttg atcagcatat gtttgaacac tttgatccaa aatctgtatt
    54841 catcaatgtt ggccgtggtg cttctgttaa gacacaagat ctggtgcagg ctttaaataa
    54901 ccagcaactt tcctttgcag cattagacgt ttttgaggaa gagcctcttc cacaagatca
    54961 tcctctttgg aaaatggaca atgtactgat tacttcccac attgcaggtt tgacacctga
    55021 ttttcaaaag aaattaatgg ctattttttt aaccaatctg aaaagctact ttgccaccca
    55081 tgagcttcaa accaatcaag taaaattgtc tgcaggatat taatagctga aaacaatatt
    55141 ttcaaaagaa aaaagagaag gtgacaaaaa ttgtgtcacc ctctcttttt ttattgtttt
    55201 ttaaagtgat aggttggctc ctccaggttg ggatcataat caacaagtaa atcatatcct
    55261 ttaaagaacc attcatctgc ttcctcgata aaaaaaagtg tcccatccat ttccactttc
    55321 tttacaggat gttctggctg ttcaactgac attccaatcg aaaaaccatc atgaacctct
    55381 gttttgccgt agacttttcc aaaaaaacgt attccgtaag tttctggcag atcaatttct
    55441 gagtcaaacc atttttgtgc ttttggcgtt accgttaatt tcatcccaac aacctacttt
    55501 ctcttttctt tctattgatt catcttatcg tctagaatat ccacatcgcc tgtctctcca
    55561 ataaccagta gattatcatt ttcacgaaca tattcatctg ctgcaggaga agcgataacc
    55621 gtttgatcta ctcttcgtat ggcgactact gttaagtcaa aacgttgcct gaaatttaat
    55681 tcagctaatg ttttgttgaa aaatttagga ttggagactc ggatttctgc taaagaatat
    55741 ttatctgaca gctctaagta gtctagaata ttctttgata ctaagttatg tgcaatccgt
    55801 atccccatgt ctcgctcagg gtgtacgaca cgatctgctc cgatcttctc tagtacacgg
    55861 gcatggtact cattttgggc ttttgctaaa atattcggta cgcccatttc ctttaccatc
    55921 agagtaacta agatgctggc ttggatatct tctccaatag cgacaattac atgatcgaaa
    55981 tttcttatac ctaatgaacg aagtgtcatc tcatcctgtg catttgccac aacagcatgg
    56041 gtggctatat tcatatattc attgactcga tcttcattac tgtcaatagc cagtacttct
    56101 tgtccagctt cgatcagtgt acggcagatg cttccgccaa atcgtccaag gcctacaatt
    56161 gcaaaatttt gtttcaccat tttcctcctt tagtatcttc ttttctcagt ataacaaagc
    56221 ctttccaaaa acaaaagcaa gcatcattat tgtaaaaaag ccaagaaaaa taatagttat
    56281 tttctcagct tttgattatc ctctttatca tcgtttttat ttcaccaaac catgtttaaa
    56341 cgcatagata gctgcttgag ttcggtcttc tacctctaac ttagctaata tattcgacac
    56401 atgcgttttg actgttttca gtgtgataaa caattcatcc gcgatttcct gattactttt
    56461 cccttcagaa atcagcatca aaatttcatt ttctcgattc gttaattctt catgcaatac
    56521 tggatcattt cgccgactca ttttttccat catttttgtt gtcacttcag gttctagtac
    56581 tcgctcgccg cgttgcgtag cccttatagc atcagctatt tcatgtgctg tagacgtctt
    56641 caacaaatat cctgctgctc ctgcttcaat tgcaggataa actttttcat catcaataaa
    56701 acttgtgacg ataatgattt tggcttttgg ccaatctttt aagattgctt ttgttgattc
    56761 gatgccatcc atttcttcca tgactagatc cattaaaatg acatccggtc gaagtgccat
    56821 cgccttttca tagccttgac gtccattttc agcttctcca atcacttcaa tgtcttcttg
    56881 gatagataaa taagaagaga cgcctaagcg taccatttca tggtcatcta ctaataaaac
    56941 ttttatcatc tttatctatg cctccttcat caaagggacc ttggtctcca cgctcgtacc
    57001 ttgcccttta aaactaatga tttttactgt tccaccaata ccagctactc gttctttgat
    57061 attgttcaat ccataacttc ccgttttggt ttcattcata ttaaatcctg tcccgtcgtc
    57121 aatgatacgt aataaaagat tgttatctat tttatgcaaa tagacttcta attcattagc
    57181 cttagcatgt cttaatgtgt ttgataacaa ttcttgaacg attcggaaca agtgatcctc
    57241 aatggaacta gttaatttta catcttctac ctcccatttt agcgaaatct ggattttatt
    57301 ctgcaattcc ttcaataact gctcaatgcc ttgttttaaa cttttttctt ctaaattgac
    57361 tggacgcaga tgaagaagca gcgcacgcat ctcagactgg gaagcgttga tgatctctgc
    57421 caccattttc aactgcttac ggaacatttc tggtgtctca cttttttctg cttgctccgt
    57481 caatgccgac atcatcatca tcgctgcaaa taattgctgt gaaactgaat catgaagctc
    57541 acgagctaat cgatgccttt ctaattttaa aatctcttct ttggtttgtc catctacata
    57601 ttgaggacgg ctagtcataa tctgtaattc actggatact tcgatcattt tttcttttat
    57661 tttagtaatt tccatatcaa tatctttgat gtacagatca tccgacgcgc ttgggatcgg
    57721 ctgatgcaaa agtttggatt cataattgcc agaagaaagt gcacgaagct tttcttcgat
    57781 tttcccgtat tttgcctttt gaataagtga taacaataga aatacgatca atcctacacc
    57841 taatgaaatt gccatcaaat ggaagataag cggaacgtat aataaacgcg cacgcagcaa
    57901 ttctccccac caatgacttt ggttactggc ataaaaataa gtgaaaagtg aaaatagaat
    57961 aataaggaaa gccgcaatcc ccgaataaac agctagcatt gctttggata ttcttcccat
    58021 catattcgta tcacctcgac atctccaacc aaagtattgg taatgatctt caatctgcga
    58081 ggattttcat cataatcact gctgcagatt ttgatctgtt cgttttttaa ggaaaactgc
    58141 tcttcttcaa acaagacatt tcctactaat gtcgcatgct ctaaacgaat agccactccc
    58201 aggggtacta agatccgtgt tctgcctatc ccttttctta caatcacaat attatcatct
    58261 tttggcaaaa gtgtattgcc caaatcgatg atagtatcac cagaaatgat ggcaatgttg
    58321 atatcatccc attcatagac gtcgtttcca atacgttggt taccaaataa ttgctgtctt
    58381 ttacgctcat tattatgtgt ttttaattgc tctgtttgga ccatcatgat ctgttttttt
    58441 cgccaaaaag cattttttgt caaatctatt cctgaaatct ctacaccttt cagcccgata
    58501 aataaaacgg ccaatacaac catcatccat aaagcaggac tgttgactaa gctaaaaaaa
    58561 atgaccaagc tccctaagat caattgaaaa ttttgaaatt tagtacgagg atatttgcgc
    58621 atagctagat atatattgaa aataccgaat attactaaaa gcaaaagtcc agtattgttt
    58681 acgatttgcc aaacagcaaa taacagcagc agtgcttcga ctaccacaaa aaaacgccaa
    58741 gaactattca tcgctttttc tccctcctga cacattctca tttcatcata cctatttttt
    58801 tgactgttgg ctataggact ttagatgtaa gatcgttcag tgaaacctgc aatactcaaa
    58861 gagaaaagat ctagagtgcg tcatcagtaa gatgaactct ctagatcttt cagtcagact
    58921 acgcttgttc tactttgacg attttaacta acatatcgcc acctggtgta gcaatggtta
    58981 cttcatcatt tttacgtttg ccaatcaatg cttgcgcgat aggagaatca ttggaaatct
    59041 ttccagaaaa cgggtctgct tcagcacttc cgacaatcgt gtactcttct tcatctccat
    59101 caggcaactc gatgaacgta actgttttac cgatcgatac ctcatctgca tctacgccgt
    59161 cattatcgat gatttgtgca aaacggatca tattttcaat tgttgtgatt cttccttcaa
    59221 caaatgcttg ttcatcttta gctgattcgt attcggagtt ttcggaaaga tctccgaaac
    59281 cgcgagcgat tttgattcgt tcaatgattt ctccgcgttt aactgttttt agttcttcta
    59341 attctttttc taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt
    59401 gtaacgtctc cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc
    59461 aaaaaagatt accacgcttt tcttaaaatg taaatgtttt tctaaaaatg atcaatgact
    59521 agcccctgtt tttctaagaa ttatttacat atttttgcac tagttccata tgttcttcat
    59581 acgttttagc gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat
    59641 tttctgctgg ttctaatact gccttgattg cctcttcgct tggattgtca aaaggaccag
    59701 gcccatagcc ggtattggta tacaaattgt atggtgaatc tacagctgta tcttcatacg
    59761 tcaccaattc tttatgttct cctaatgcat ataaaacaga gatatctgac tgaagtggca
    59821 tatttgcctt gattcggtta aagaagactt gtgcaatatt tttacgatca ttttctttta
    59881 cgccttcttt ttcaactaga gaagccaaag ttaaaacttc ttgtacagtc aaatttttct
    59941 gtttgatagc tgaataatag ttttgcatga ccgtatttgt tttgttcacc atctcaatca
    60001 caagatcctt aagcgaagta ctcgtgtagt aatcataagt agctgggaat aagtagcctt
    60061 ccaaacggta ttttgtgttc tcagctttag aggcactttc caacaattct gggaattttt
    60121 gatacaactc gttaaagaaa gtctcatcat ttactaaatc taaaaattct ttcttgtctt
    60181 taccagttac cttcgctacc cgctcagcaa tctgatcgat gtcgtagcct tctggaatgg
    60241 caattttccc atctgcaact tttgttggct cagaagtgcc gccttcttgc agctgtttgc
    60301 caatctcgtc aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta
    60361 aatttttaaa ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct
    60421 ccaaaatctc accaatctgc ttgttagaag agccactcgg gatctccact tggactaatt
    60481 ggtcatctga tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc
    60541 caagaaatcc gccaataatt aataatgtaa gagcaatcac taaaatgatc ttcctcacaa
    60601 tcttatcttc ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct
    60661 tactggcttc ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc
    60721 cttactatca tcttcgtaac tctgtttatt atacatgaaa tttctactgc cgtgaattat
    60781 tttaccaaat attatgtcaa aattgtaagt ggcaaatact ctttttgagg attacaatga
    60841 aaaatagtta aaaatggata gaaaggaatt aacatgtcaa aaggaaaaca tcgaaaaaaa
    60901 caaaaaattt ctatttcttt tcttgtaatt ttattattgt ctgtcagctt cttttcaaca
    60961 ggcatcatta taggaggtca attaacaaaa atacctcatt cccaaactta taaagcggag
    61021 ccaacacaac ttacttccaa tttaacgccc gatgagcaga ggcttgctag caaaattgat
    61081 caattactac aaaaatcaga ttatatcggt tcgatttatg ttcgcaaaaa taatcgcgta
    61141 ctattagaaa aaggatatgg atatgcaaat ctgcgcgtaa aagaatcgaa ttcaccttct
    61201 atttactatc aaatcggttc gattcaaaaa gcaatgactg ctttactgat actaaaacaa
    61261 atccaagctg gtaagttaac ttttgacaca aagttagcag aattttatcc tcagattcct
    61321 ggaagtcagc aaatcacaat caaaaatatg ctttatatgc gctctggtct tcatcgaact
    61381 gcttctcccg acaaacctat gtcggatagt gaaatcattc agttcgccct tcatcatttg
    61441 aaacttactg attatgatac gtatcattat gaaccattga attatacatt gcttacaggg
    61501 atattgatca aactaacgaa tcagccttat gaaactcttc taaaaaaaga aatcattcgt
    61561 ccactccatc tagaacatac agatttttat gacaatgtaa aaaattcgcc tcaacatgct
    61621 gtatcttacc agatgtctgc aactgacgat tattcaaaag cattgatcga gcctgaaacc
    61681 gacatccgaa atgaattagg tacaggaaac ataagtatgt ctgtttatga cttgaacaaa
    61741 ttctttacca gtgttctttc tggcggtatc ataccaaaag aactactttt ctcattgtgg
    61801 caaaataatg gtgataaaca tccttacagc ggcggtgttt acagtggaaa cgattatatc
    61861 cttgctcagg ggaatatcaa tcgattccat gcagtagtgg cgatgaaaaa agacactaaa
    61921 gatgcaatcg tcatggaaag taatatccaa tcggataaga acatcaaatt gccggccact
    61981 gatttaagaa atcagattta tgaactgatg gaaggtgttc acttatcaaa ttaaattttg
    62041 acataatatt agttgtcatc tctgtatagt caatttagtt agtactctat ctgaaaagta
    62101 gaaataaatt aacaaatatt atctgtcctt attatttgtt aatttatttc ttatttta
//
LOCUS       DAIGQM010000007        61534 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.007, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000007 DAIGQM010000000
VERSION     DAIGQM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.007"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(59..187)
                     /locus_tag="NOA48_000396"
     CDS             complement(59..187)
                     /locus_tag="NOA48_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0788695.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOA48_000397"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOA48_000397"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0788696.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="NOA48_000398"
     CDS             complement(1674..2729)
                     /locus_tag="NOA48_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0788697.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOA48_000399"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOA48_000399"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCI0788698.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOA48_000400"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOA48_000400"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCI0788699.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOA48_000401"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOA48_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCI0788700.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOA48_000402"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOA48_000402"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCI0788701.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOA48_000403"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOA48_000403"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCI0788702.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="NOA48_000404"
     CDS             10491..12050
                     /locus_tag="NOA48_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCI0788703.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="NOA48_000405"
     CDS             complement(12161..14092)
                     /locus_tag="NOA48_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0788704.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOA48_000406"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOA48_000406"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI0788705.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="NOA48_000407"
     CDS             complement(15021..15773)
                     /locus_tag="NOA48_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0788706.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="NOA48_000408"
     CDS             complement(15932..16141)
                     /locus_tag="NOA48_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788707.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="NOA48_000409"
     CDS             complement(16152..17480)
                     /locus_tag="NOA48_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788708.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="NOA48_000410"
     CDS             17616..17771
                     /locus_tag="NOA48_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788709.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="NOA48_000411"
     CDS             complement(17845..18432)
                     /locus_tag="NOA48_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCI0788710.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOA48_000412"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOA48_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCI0788711.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="NOA48_000413"
     CDS             complement(20012..21301)
                     /locus_tag="NOA48_000413"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCI0788712.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="NOA48_000414"
     CDS             complement(21455..22387)
                     /locus_tag="NOA48_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788713.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="NOA48_000415"
     CDS             complement(22544..23203)
                     /locus_tag="NOA48_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0788714.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOA48_000416"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOA48_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCI0788715.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="NOA48_000417"
     CDS             complement(24244..24534)
                     /locus_tag="NOA48_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788716.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="NOA48_000418"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="NOA48_000418"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCI0788717.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="NOA48_000419"
     CDS             complement(26821..28176)
                     /locus_tag="NOA48_000419"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCI0788718.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="NOA48_000420"
     CDS             complement(28200..29369)
                     /locus_tag="NOA48_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788719.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="NOA48_000421"
     CDS             complement(29366..30253)
                     /locus_tag="NOA48_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCI0788720.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOA48_000422"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOA48_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCI0788721.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMTIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="NOA48_000423"
     CDS             34320..34841
                     /locus_tag="NOA48_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0788722.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="NOA48_000424"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="NOA48_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="NOA48_000425"
     CDS             complement(36284..36940)
                     /locus_tag="NOA48_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788723.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOA48_000426"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOA48_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCI0788724.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="NOA48_000427"
     CDS             complement(38477..39475)
                     /locus_tag="NOA48_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCI0788725.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOA48_000428"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOA48_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCI0788726.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="NOA48_000429"
     CDS             complement(40491..41222)
                     /locus_tag="NOA48_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCI0788727.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="NOA48_000430"
     CDS             complement(41226..42491)
                     /locus_tag="NOA48_000430"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCI0788728.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOA48_000431"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOA48_000431"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCI0788729.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOA48_000432"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOA48_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCI0788730.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="NOA48_000433"
     CDS             47833..49335
                     /locus_tag="NOA48_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCI0788731.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="NOA48_000434"
     CDS             49337..50074
                     /locus_tag="NOA48_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0788732.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOA48_000435"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOA48_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCI0788733.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOA48_000436"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOA48_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCI0788734.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOA48_000437"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOA48_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCI0788735.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOA48_000438"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOA48_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCI0788736.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="NOA48_000439"
     CDS             complement(55574..56740)
                     /locus_tag="NOA48_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCI0788737.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="NOA48_000440"
     CDS             complement(56756..56983)
                     /locus_tag="NOA48_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCI0788738.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="NOA48_000441"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="NOA48_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="NOA48_000442"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="NOA48_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="NOA48_000443"
     CDS             complement(59476..59637)
                     /locus_tag="NOA48_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788739.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="NOA48_000444"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="NOA48_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="NOA48_000445"
     CDS             60827..61417
                     /locus_tag="NOA48_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCI0788740.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17078 a        13211 c        10646 g        20599 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagtcat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacatgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAIGQM010000008        59494 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.008, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000008 DAIGQM010000000
VERSION     DAIGQM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.008"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(278..1588)
                     /locus_tag="NOA48_000446"
     CDS             complement(278..1588)
                     /locus_tag="NOA48_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI0788741.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1600..3018)
                     /locus_tag="NOA48_000447"
     CDS             complement(1600..3018)
                     /locus_tag="NOA48_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0788742.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3258..4826)
                     /locus_tag="NOA48_000448"
     CDS             complement(3258..4826)
                     /locus_tag="NOA48_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0788743.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4830..5240)
                     /locus_tag="NOA48_000449"
     CDS             complement(4830..5240)
                     /locus_tag="NOA48_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCI0788744.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5237..6160)
                     /locus_tag="NOA48_000450"
     CDS             complement(5237..6160)
                     /locus_tag="NOA48_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCI0788745.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6157..7035)
                     /locus_tag="NOA48_000451"
     CDS             complement(6157..7035)
                     /locus_tag="NOA48_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCI0788746.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7022..8358)
                     /locus_tag="NOA48_000452"
                     /pseudo
     CDS             complement(7022..8358)
                     /locus_tag="NOA48_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
     gene            complement(8361..9464)
                     /locus_tag="NOA48_000453"
     CDS             complement(8361..9464)
                     /locus_tag="NOA48_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0788747.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9538..11046)
                     /locus_tag="NOA48_000454"
     CDS             complement(9538..11046)
                     /locus_tag="NOA48_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0788748.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11012..11704)
                     /locus_tag="NOA48_000455"
     CDS             complement(11012..11704)
                     /locus_tag="NOA48_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0788749.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11726..12700)
                     /locus_tag="NOA48_000456"
     CDS             complement(11726..12700)
                     /locus_tag="NOA48_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788750.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13000..13872
                     /locus_tag="NOA48_000457"
     CDS             13000..13872
                     /locus_tag="NOA48_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0788751.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14330..16528)
                     /locus_tag="NOA48_000458"
     CDS             complement(14330..16528)
                     /locus_tag="NOA48_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0788752.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16760..17752
                     /locus_tag="NOA48_000459"
     CDS             16760..17752
                     /locus_tag="NOA48_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0788753.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17812..19233
                     /locus_tag="NOA48_000460"
     CDS             17812..19233
                     /locus_tag="NOA48_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCI0788754.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19226..20725
                     /locus_tag="NOA48_000461"
     CDS             19226..20725
                     /locus_tag="NOA48_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCI0788755.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20764..22158
                     /gene="uxaC"
                     /locus_tag="NOA48_000462"
     CDS             20764..22158
                     /gene="uxaC"
                     /locus_tag="NOA48_000462"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCI0788756.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22317..23000
                     /locus_tag="NOA48_000463"
     CDS             22317..23000
                     /locus_tag="NOA48_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCI0788757.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23002..23838
                     /locus_tag="NOA48_000464"
     CDS             23002..23838
                     /locus_tag="NOA48_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0788758.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23849..25603
                     /locus_tag="NOA48_000465"
     CDS             23849..25603
                     /locus_tag="NOA48_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788759.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25879..26220)
                     /locus_tag="NOA48_000466"
     CDS             complement(25879..26220)
                     /locus_tag="NOA48_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0788760.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26288..28459)
                     /locus_tag="NOA48_000467"
     CDS             complement(26288..28459)
                     /locus_tag="NOA48_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0788761.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28628..29527
                     /locus_tag="NOA48_000468"
     CDS             28628..29527
                     /locus_tag="NOA48_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0788762.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29598..30455)
                     /locus_tag="NOA48_000469"
     CDS             complement(29598..30455)
                     /locus_tag="NOA48_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0788763.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30440..33142)
                     /locus_tag="NOA48_000470"
     CDS             complement(30440..33142)
                     /locus_tag="NOA48_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCI0788764.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33155..34444)
                     /locus_tag="NOA48_000471"
     CDS             complement(33155..34444)
                     /locus_tag="NOA48_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCI0788765.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34594..35640
                     /locus_tag="NOA48_000472"
     CDS             34594..35640
                     /locus_tag="NOA48_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0788766.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35642..37795
                     /locus_tag="NOA48_000473"
     CDS             35642..37795
                     /locus_tag="NOA48_000473"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCI0788767.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38268..39719)
                     /locus_tag="NOA48_000474"
     CDS             complement(38268..39719)
                     /locus_tag="NOA48_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788768.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39716..41440)
                     /locus_tag="NOA48_000475"
     CDS             complement(39716..41440)
                     /locus_tag="NOA48_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0788769.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41433..42047)
                     /locus_tag="NOA48_000476"
     CDS             complement(41433..42047)
                     /locus_tag="NOA48_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0788770.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42392..43849)
                     /locus_tag="NOA48_000477"
     CDS             complement(42392..43849)
                     /locus_tag="NOA48_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0788771.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43890..44810)
                     /locus_tag="NOA48_000478"
     CDS             complement(43890..44810)
                     /locus_tag="NOA48_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0788772.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44822..45769)
                     /locus_tag="NOA48_000479"
     CDS             complement(44822..45769)
                     /locus_tag="NOA48_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788773.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46248..46967)
                     /locus_tag="NOA48_000480"
     CDS             complement(46248..46967)
                     /locus_tag="NOA48_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0788774.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47016..48662)
                     /locus_tag="NOA48_000481"
     CDS             complement(47016..48662)
                     /locus_tag="NOA48_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0788775.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48841..49431
                     /locus_tag="NOA48_000482"
     CDS             48841..49431
                     /locus_tag="NOA48_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0788776.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49523..51028
                     /locus_tag="NOA48_000483"
     CDS             49523..51028
                     /locus_tag="NOA48_000483"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCI0788777.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51112..52464)
                     /gene="celB"
                     /locus_tag="NOA48_000484"
     CDS             complement(51112..52464)
                     /gene="celB"
                     /locus_tag="NOA48_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0788778.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52464..52982)
                     /locus_tag="NOA48_000485"
     CDS             complement(52464..52982)
                     /locus_tag="NOA48_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788779.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(52998..53324)
                     /locus_tag="NOA48_000486"
     CDS             complement(52998..53324)
                     /locus_tag="NOA48_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCI0788780.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53337..55316)
                     /locus_tag="NOA48_000487"
     CDS             complement(53337..55316)
                     /locus_tag="NOA48_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0788781.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55337..55651)
                     /locus_tag="NOA48_000488"
     CDS             complement(55337..55651)
                     /locus_tag="NOA48_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCI0788782.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55819..56112
                     /locus_tag="NOA48_000489"
     CDS             55819..56112
                     /locus_tag="NOA48_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCI0788783.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56190..57302)
                     /locus_tag="NOA48_000490"
     CDS             complement(56190..57302)
                     /locus_tag="NOA48_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0788784.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57689..57868
                     /locus_tag="NOA48_000491"
     CDS             57689..57868
                     /locus_tag="NOA48_000491"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788785.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58062..58232
                     /locus_tag="NOA48_000492"
     CDS             58062..58232
                     /locus_tag="NOA48_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0788786.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58656..>59494)
                     /locus_tag="NOA48_000493"
     CDS             complement(58656..>59494)
                     /locus_tag="NOA48_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0788787.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17787 a        12163 c        10408 g        19136 t
ORIGIN      
        1 gatttcgttt ttcgaaatct ttcagcaact catttatcat aacttatcgt ttgttatttg
       61 tcaagaactt ttttgaagtt tttttcgata gaatcaagct tcgcaagtgg ttctttttaa
      121 cgacttagtt atcttatcac gtctaaaaac atgtgtcaac tcttttttgg aattttcata
      181 aaatgtttca atgaagcgcg acaacgttgt ttaatatatc attaaaaaaa ataaaggtca
      241 agctaaaata ttatttaagc ttgaccttat tataatttca acgattgtca aaagtattgt
      301 ttgcagctgt gttgccagtt tctatagata aatcacagct tttgaaacat aagttttgta
      361 ctgcttcgat tcgcccgaat tcttttgcag ttatttggca atgagaaaag cagacatctt
      421 ctataggctt ttcaggaaat gctactaaat caaaagctcg ggaaggaagt gagtaacctg
      481 gagaaaggca tgcctgtacg tttttgatgt gtatgtcttt gactttcgtc atttgctttg
      541 attcaggtat ttcttcagcc actgcttgcc aactttctgg catttgagca aggtcattgc
      601 tattttttct attgtattca ttatgccagt ccattatcca agaaaaagga aattgtacat
      661 caatcatatt cagattttct accctgatat tttcgatcac tccccctctt tcttttgaag
      721 atttcattcg aataccacag tctgactgaa aaaaatcgat atcgtgaata tatacgtcac
      781 taactccagc actaacttcg ctaccaatag ttacaccgta tcctgaacgg attttacatc
      841 tagcaacctc gattcttgat gattttcgat tgactcttgc accattgcca tctctgccag
      901 acttaatagc aatacaatca tcaccacagg ccaaatcaca ttcatagaca cgcacatttg
      961 ttgaagaatc aatatcaatc ccatctgtac ttggtccatc attgttgcgg atgattactt
     1021 tttctactaa tacatcgtta gaataagtga tttgcaagtt ccaaaaacct gatttctgaa
     1081 aaatcaaatc acgaacaaca acatgttctg catgatacag taaacaagcg cgtggacgtt
     1141 taatagcata atccgcaatc caacgaagtc ccttttgatc gtattcagct cttgtcccgc
     1201 ttttttgatc ttttccccaa tacagctccc accaatggtc tccttgaccg tcgattattc
     1261 cttttccttc tataagaata tctttcgccg agagaacatt caaaatcgct gctggccatt
     1321 tcatttctac gccggctact cgtgtatcga tttctggaaa tgcttcgata tctgttctcc
     1381 ccttgaggac tgcaccttct tcaaagataa gatgactctt atcttttaaa aaaagggctc
     1441 cgactaaata aatgcctttt ggaataaata caggtaagtg ttctttcgca ccttgatcga
     1501 ttgctttttg cagtattatt gtatcatctt gttgagtgtc gtttgtttta aagttcaaag
     1561 cattgataat cccttttttt gtccgcaata cgtttctccc tatctttcat tgattttttt
     1621 caattcttca ccaataaata cagtttttga acgattcagt gggtaaccta ctagcaaaat
     1681 gattgcggat acaaataagc agaatgctgg taacaagttt gccatcgtat aaatcctttc
     1741 ttgtactaaa actgattgga tggctccacc tgttgtagac gattggtaac caatgagtgc
     1801 cagcataaat ccgcctaccg ctcctgcaca tgcttgtcct acttttctcg caaaagaatt
     1861 tactccatat actgttccat cttctcttaa gcctgtctta tattgatgat aatcaatcac
     1921 gtcagtaatg aatgcccaga ccatcaaatt gaataaacca gatcctaaag tagcgataaa
     1981 taaaagaatc agatataccc atgcatttgt tatatgaagg aaatacatca gcaagtacat
     2041 acatgaagaa gcaagtaacg caaatacgct tgcttccttt ttaccaaata attttgtcag
     2101 ctttgtagca aatggtgcta aaactactac tgttccgtaa gtaaataaaa gagcaacaga
     2161 cattgcttgt ttattatgga agtaatcatt gaataaataa gtcatattcg tcccagctaa
     2221 aatctgattg atcacaatga aaatgtcaac aatgactaaa ataatcagtg ctcgattagc
     2281 taacaaacct tttaccaact gagaagcaga tactttttcg tttttgacaa ctcttactct
     2341 ttcagtagtc aatttacaag ttaacatata tgcgacaaat gctattgcag cacatccgat
     2401 tgaaatccaa aagaaatgat tccctgaaac gacttgttgt ccactcttgt tatgggtata
     2461 cattaaaatc ggaatgaaga atcctgtagt tgatccgcca atcgcagaac caatgcttcg
     2521 gaacgtggac aacgaggtgc ggtcattagg atttgagcta attgctgctg ccattgctcc
     2581 atacgggata ttgattgttg agagaaaaat cccataaaca atgtatgaaa caaaaatata
     2641 agcaatcttc accgtcattg gaagatgttg gacgaatggc aaaaacaaaa tgacagtcac
     2701 taagcaaaat ggatacttca tttttctgat ccaaggaata aatcggccag tttctgttaa
     2761 ctctgagaca tcacataatc ttccaaccat cacatcagca aacgcatcca aaattctcga
     2821 aatcaagaat aacgtaccta cgattgcccc tgaaacgcca agaacattcg tataataaat
     2881 catcaagaaa ctattgacta aacctaaaat aaaacagtta cctagatcac cgaacatgta
     2941 gcctatctta tcggaaatcc caaattcctt tttttctttt tttattgtat ttgctgtaac
     3001 agcattttgt gaaagcattt gaattcctcc tacctcttct agtaaacgtt ttcaaaatta
     3061 taactctttt tttcttgttt ttatattcac aatgttggct ttttattgca ttatcttgac
     3121 agataaaaaa caaaaaataa tctaaaaaca ttgatgcata agattgataa ctttttttac
     3181 ataacaatat atacaaacaa aaaaattcac taactagtga aaataagtta gtgaacctca
     3241 tttattaaag aattaaatta cagatgatct tttccatcat acttgaaaaa ctcaaaatca
     3301 gcataacttc ctcttttttt atttagatca tgcactgcta tcccgataaa atttccagta
     3361 aaccctcctg agagtataca catgtttttt tgcggaccta ctttcttcca ttcttcagtt
     3421 gatacgtctt tcaaatgaaa ctgtgctgtc tctttcttta cagtgacttt caaaaaagtc
     3481 ttcttttctg tgagtggaat cgtccaatct tctatttgtg ctactccgtt ttctgattct
     3541 atcatacgta ggcattttcc cttgtcctca ttccaagtaa cataacaata aatataattg
     3601 gattcattta agtacagtac cagtccagcc atctgattaa aattattagg catgtattca
     3661 aatgctgtct ccgcatcaaa agtaaaatcc gtttgccgaa tagctaacaa atgatgttcg
     3721 aaggtagatt gaagagattc accggaaatc agacgtaaaa aacctggtct acattttgta
     3781 tcacaccaat cagcatttgg caaaatgcgt ctggcattcc agttcttctt tagctctcct
     3841 tcaaatgtat ccataaactg atgatctttt tcttgttgta cctcttcatt tgtctcaatc
     3901 attatttctt ccatcggagt tgtctggcta tctttaagtc ttaaccaatc gtcggacgtc
     3961 caatacactt cttgaatagc ggtttctctt cccaaaatag ccgcaccgtt taatggtctg
     4021 gtacaaagat atgtcatgta ccatcttcct gacggggttt gtactaagct cccatgtcct
     4081 gtacattgca atgtagaagc aggtttgtca ctagctgtca gcataggaaa accaggatca
     4141 agctcgtaag gaccagtaat attctttgct cggcaaactg taactgaatg tcctcttcct
     4201 gtaccgcctt ctgccgtcat caaataataa tacccgttac gaaaatacaa atgtggtgcc
     4261 tccgttttcg ctaattctgt acctgcaaat attttataga tgggaccatc aagcttcttc
     4321 ttctctgcat catattcttg taatacgata ccgctggatt tattcggtgt gtccagacga
     4381 taatcccata gttcattgac aagccatttt tttcccgttt caagatcatg gaacaaagaa
     4441 ggatcaaagc cgttactatt taaataaatt ggttcggacc aaggacctgt gatctcagat
     4501 gcagtgatca aataattgtg gacatcttta aacggacggc ctgcactttt gacatctgtg
     4561 taaacaagat aaaacaatcc atcagcataa ctgatctgtg gcgcccatat acttccattt
     4621 gtaggatttc cttgcaaaga tacttgagtg gtcaaaatat ccgttgtatg tgaccagttg
     4681 actaaatttt tcgactcata tactcggatt cctggaagcc attcaaaaga ggagacaata
     4741 atgtaatacc gctctttcac tcttaatata ttaggatctg gattgaatcc tcttaaaata
     4801 ggatttttca ctttgatagt ctgcatgatt caggctcctt ttctcattct tactcgatat
     4861 aaactgaatg ccccagctgc gaaataaaaa aatgcaaaag gaaacgcaat aaactgagtg
     4921 ccaatcaaca atatgaatcc tgttataaaa tacaaaccag tggcagttgt taagtatttt
     4981 cctttagcag tcaaaaacaa tgctactgct aaaaaagcaa gtgaaataaa caacacaacg
     5041 gcaaacagac cagtcatgtc ctgtaataat ccaaatgtat tttctaaaga caaagttgaa
     5101 tgatctacag caagcgactg ataacttttt ttaaactctg acgcagacat attacttaaa
     5161 gtaactgcta acccgccaaa gaaaatcaaa gatagactgc caccgaccat tcctagcaat
     5221 agttcccatt ttcttttcat ttctgaaccc cctgcttttc taaatgtatc cattcaggtc
     5281 ttttgatcga tgtttcataa ttgttattac gttcagagaa tttgacagtc tgttcatttt
     5341 tcttgtcatc ccaattatcc caaccagttg ggtgaacatg cccacctatc ttacacgctt
     5401 caaataagac atttgcatac ggacgccacg gtcttcctaa atagacgttt ctagtatcag
     5461 gttctgcagt caaggtacag ctttcaaaac gataccctgt tttttgattt ttcggcgtag
     5521 atgctgctgt gatgtatcca ggatttttac tggctaagct atggatatga cactgatgaa
     5581 aaacggcatc tgccccacca aatatgaaat ccaccgttcc ttcaatccag caatattcat
     5641 aggtctgacg acaatactca ggattggcag aagccggtgt acaaaaagga gtaccatctt
     5701 tttgcaaatc aggcaacgga cccgtgcata aggtatcctg ataaccagat agtcgacagt
     5761 tttttaaaga tacgcgatct cctgaattga ataaagcaac agcctgtcct accttttctc
     5821 ctggacctgc tgtattttcg atgtgaagat tttctaatac gacattcgat ccttctaaga
     5881 aaaaagtagc acttcggaaa gtccctaact ggctaccgtc aagatactcc tgttttgcaa
     5941 aacgattacc ggagataact actgttcctg ctcccacaag tttaaaattg gataatctgc
     6001 tttctatata ttcatcatat cttccttctt ttactatcaa gacctttgga tggctatccg
     6061 gcaggcctgc caaataatcg attccttctt ggatagtttc aaaatccgtc ggggtatcta
     6121 tagcattctt tccaattatc agtttgtctt tcatcctcat aaatgctccc ttatgaattg
     6181 tttccaaata tttctcattt cttgtgtttc catatgaccg cctgttaaag aaaaagaaga
     6241 aaagttttct ggactaccca ttgattgata ctttttgtcc agcccttttc tcagcttcag
     6301 tacgccttcg tccaagcaca tcgtatcgtt ttttccaact aagctaagac gagggcgcgg
     6361 agcgattttt tcttggattg ctaacgttgt ataagctgtc aatagatttg gcacatagta
     6421 ataaaaccca tgatgatcta ggcggcgatg tagcaaaagt atttcgatgt ccacctgtgc
     6481 cgctagatca atacaaactt tgacacgaga atccaatgct gtcacccacc agcttaataa
     6541 gcctcccata gaaagaccaa tcgttgcgag ccgttgagta tctgtgtctt cccttgtctc
     6601 caaataatcg atcaagctga tcacatcata aatacgcatt ccccataacg tttttcctgt
     6661 taataaaaat tgtttgaaca actcgctttc agaaatacct ccgcgttctt caaatcccca
     6721 agcatcaatc gaccaaacag catatcccat tcctgtcagt acttctgcaa aagatggaga
     6781 agctaagtaa ggagcaccat ggatcaattc acttttcccg actgaaaaat ctccgccgtg
     6841 agaatgcagg taaaggaccg gcggaaacgg tccttctttt tctggataag catagagggc
     6901 tggtactgtt tccaattcat ttaagtacaa ttgatagtat tcaagcataa aaccgttttg
     6961 tttttctcgg tataatcgtt ttccactagg ggtatgtctg ctagatggag cacctaaaaa
     7021 atcattcaac tgcataagca aagtttttac gaacaaccag ttcatccata ttttctgatt
     7081 gatttgattg gaatttctca atactgattt ctttagtatt ttctaataga aatgctggtc
     7141 cctcgtgatt ttcaatcgac atctggttaa aggaaacctt acccgcaaag ccaatataaa
     7201 atccttgtct gctcatttcc tctattcctg tcatcatagc aggaacaccg ggaactgcat
     7261 cttgggccat cgagacatcg atattgtcaa atgtgatttc ttgtatgaat tgttccgcta
     7321 atccataaat aaaacctgca gaagcatgga cattccttgc cgtgatattc gaaaaatgga
     7381 tccttctgaa tgctggtgtc cgttcatcta tcggataagc cttttttccc atacatacgg
     7441 ttctttccct cgcggaccac agaaataata aagattcagt ataaatggac acatcacatt
     7501 atccatgact atattggata ctcgaatatc ttcaacgatc ccgcctcgac ctcgtctaga
     7561 tttcaatcgt attcctcgat cagtttcttg gaagatacaa tttgaaatgg taatattacg
     7621 aatactacca ctcatttcac ttcctaatac gacaccgcca tgtccatgga ccatcgtgca
     7681 atttgtgatc gtgatatttt cgcaagcgat cctttcgtac gtatcttcag tccctgcctt
     7741 gattgcaata cagtcatctc ccacgtcaat atggcaatta ctaatacgca catttttgca
     7801 tgattctgga tcaattccgt ctgtatttgg tgaatccgct gggttcaaga tcgtcaagtt
     7861 atcaaacgtt gcattactgc aaagaatcgg gttgatcgtc caacttggtg actggatcaa
     7921 tttaatatct ttcacagtaa ttcgatgaca gttatggaaa ctcatcaatt taggacgagg
     7981 ataagcgaga ttatctggtt catttctaaa agtatgccac catttttttc catttccatc
     8041 taatgtaccg aaaccagtga cagagatgtt ctctacattt tgagcataga tacaggaagc
     8101 ataaactttt cgatggactc cttcccaacg tgaatgaaca acaggataat cttttggatc
     8161 gtcagagaat ttcagaaccg ctcctgcgct taaatgaagt tcgacattgc tttttaaaaa
     8221 taaagctcct gttagaaatt cacctgctgg aacaactacg gtcccgcctc cgtcacttgc
     8281 tgcagcatca atggcttgtt gtattgcttc agtattcaat tcatcaattg atgcgccaaa
     8341 tgtcaaaata tcatacatat ttataatgcc tccacttcaa tcaatgcttg caagaatgca
     8401 ccaacgcctt tttgatcatt acaaataatt ggttcactga tgtagtaagc atatgaacca
     8461 tctcgctgat ctgctccgcc taaccctgct acttgacagt ttttattcaa gttcagccag
     8521 ccttcttttg tttccagaac aaattcatca agtaatcctt gatgtgattt cttcacttgt
     8581 ggaagccatt cttctttgtt cagcagtccc aaacgtattc ctttagccat tgcgtaaaca
     8641 aacatactac tgccggaagc ttccagataa tttcctttcc gttttgtttc tgttgttact
     8701 tgataccatg tcccgctgtt ttcttcttga tatggaagta atgcagccag tgtcttttct
     8761 agaatttctt tcagcaaaga acaatctgtt tcttcatgaa gtaattcata ggtatctgct
     8821 gcagccatca aataccagcc aatcgatcgg ctccaaaaat gatgggatag acctgttttt
     8881 ggatcagccc atggttggac cttcttttca tcccatgcat gaatcagcaa atttgttttt
     8941 ggatcgaata gatgtttata actgatttca aactgtctca aaacatcttg gtaatctttt
     9001 tcttcactaa aattctggat aaattcagca taaaaaggag aacccatata taagccatcc
     9061 aaccaaattt gataaggata aatttcttta tgccaaaaag ctccttcgga tgtgcgtgga
     9121 tggtttgcca actgctggga aaggagttct gctgcttttt tatatttttc ttcgcctgtt
     9181 tctttgtaca ataaaaagaa aagctttcct gtatttacat ggtcgatatt gtattcttca
     9241 acgctgtagc cacggatcgt tccatcttct tgcacgaaat agtcgatatt gtcttttatg
     9301 aaatcaaaat aaattttttc ttgggttcgt tcccaaagta attggaaccc tttaagtacg
     9361 acgccatagt cataagacca ttttccttta taccactttt cttcatataa gcgaggtgtt
     9421 ctttccatga tactttttgc taatttcttt gaccagtttt ccattatttg ctctccttta
     9481 aaaattaaaa taggatttgg gacaaatacc aagaagtatt tgtcccaatc gtctatatta
     9541 ctgtgccgct gctttgtatg cttcctcgta ctcttgtgtg attcgatcgc ctccttgtgc
     9601 tttccagtct tctacagctt ttttgaatcc atcttcgtca agctgtccca tgatgtattg
     9661 caccgtagca tcaatgacga ttttttcaat ttctgatcct acttcattgt tcgtcggtga
     9721 atccaatggc acagaaggat ccattacagc aaattcttca ttttctttga tcaattgatt
     9781 agagaattct ttttcagggt ctgtatcttt gaaagagaac gtcacttcac taggacgaga
     9841 gcttgataac ggttgcacct cttgttgcca aagatccata tcgataaatt cgatagaacc
     9901 atcatcattc aattcataat gcgttccttc gataccgcca gtcatcaatt tatacacatc
     9961 ttcttctaaa agatcatcaa caaattgaag taatttcttc aattgtgctt cgtcttttac
    10021 ttgagatttg ggaaatgcta gcaagccgcc aataccattt ccttctgacc aaacatgata
    10081 accgccgcct tcaccatctg agatcttgtt tacaggcact aattccatat catcttgaat
    10141 accttgaccc atcgtcttca gattcttgat atccaccatt ccagtgtaga ttccagttct
    10201 tccttgtgca aattgttctt gctgatcagt cttttgggta actgcaaagt cttgtgccaa
    10261 atagccattc tcaaatagat ctcttgaaaa attcaaagct ttcatatact cttctgtatc
    10321 aaattctgga gtgaatttgc cattatcgtc tacagcccag ccatttggtg ctccaaaata
    10381 agaagtgaaa agtttaaagc tggtataacg aatatcacta ggcgcacgat cgccaaaacc
    10441 aactgtgtcg tccacaccat ttccatcagg atcgttttct gtaaattgtt tagctacttc
    10501 ataaagctca tccatggtag ttggaacatc tagtcctaga ttatccaacc agtcttttcg
    10561 aatgactaag ccagcacgag cgtagtcttt ttgtatcggt acgccgtaca aggcaccgtc
    10621 gatactcgca gcttcgattc tatcttcaga aatttgactt aaatttttat agtcttttaa
    10681 atattctgat acatcccaga atacgcctga ttttaacgca ttgcggacag aagagttttt
    10741 caacatcgca atttgaagtg taacgatatc tcctagttca tcagaagcca atgcagttgt
    10801 taatctttct tcttttgaag catcaggaat ccagttgaat gtcagttccg tatcggtttt
    10861 ttcttcgatc aagttcacaa tcgtgtctgt aggcggtgaa gcatgatgca aaatatttaa
    10921 ccaagtgatt ttagcttttc catcttctgt ctctgaagaa ctgttacttg aactgctgcc
    10981 gcatgcggca agtgctagaa ttcctgcaaa actaagacct aattttacga gcgttgcttt
    11041 tttcataaat tttctccttc actgttttaa taatattttt gttttcttct gttttttctg
    11101 tatatgagtt cttccattcc aaatggcaaa atatagaatt tgctgtccac gtgactgcgg
    11161 aaaagaagag actgccaccg ataaaggtta aaacacctgg cattgtttgg atgatcatca
    11221 gataaatccc taccatactt aatatcaaca ctaatgagta atgaagatgt gagaatccga
    11281 ataaaaatgc cattttcatt ttgaaaaaat atcctttcca atcataatga gccatgattg
    11341 ggaaaatata gagtgctgag agcacatata tgaacgcagc aatatacaaa gcgatcctaa
    11401 gataccaatt gtgtatgaaa gaaagatcca caagtaaaac aatcccgatg gcgccatata
    11461 tccagctcat cagcaaggtt tcacgatagt tttctttaaa atatgtgaag tacgttttcg
    11521 tcaaaggaaa cgtttctttt gagcgcagcc attttctaat cactgcaacc atcgcatacg
    11581 atgcaggacc gaaagtaaaa actcccaaac ctgcgatgac taaaccgccc cacagaaaat
    11641 tcaaataaac caactgtaaa atacgattta gccttccgtt tattttatct aatgactgca
    11701 gcatatcttt ccctctcttt ctatcttagt aaacgccgtc ttctcctagc tttttggcaa
    11761 tcttattagc taaaattacc ataaacaatc ctacgacccc tttaaacaat cccattgctg
    11821 tactgaaact taactgtcca ttcttcaatc cagctgtata aatataggtg tcgaaaattt
    11881 ctgcaacgct tcgattcaat gaattcaata acaagtacat atgctcgaac cctaagtcta
    11941 atgtctgacc gatttttaga atcagcaagg taatgattac tggacgaatt gccggcaatg
    12001 taacatgcca tgttttgcgt aagcgtcctg ctccatccat ttctgcagct tcatacaact
    12061 gtgtatcgac tgcagttatc gctgaaaggt agatgatcgt agaccagccc aactctttcc
    12121 agatcacttg tccgatatat actgtgcgtg tccattcagg ggatgttaga aaactgattt
    12181 tttcaaatcc cattgttgca aggaattcat tcaatacccc tccgtcaaca ttcaaaaata
    12241 cataagtaat cgaaacaatg attacccaag acatgaagtg agggatgtaa atgatcgttt
    12301 gaatcccgtt tttcaatcgt ttgttcgtta cttcatttaa tagtaaagac aaaatgattg
    12361 gcatcggaaa aaacacgaag atatttaatc cgaacaagat caacgtattt cttaataatg
    12421 taaagaatgt cggttctgta aacaaacgaa tgaaatgttt gaaaccgacc caaggacttc
    12481 ccattattcc taaaaatggt tgataatctt gaaaagcaat aacgagtccc cccataggaa
    12541 gatacctaaa aatcaagaaa taaaggactc ccggcagaat catcacatat aaaaatttat
    12601 tcgttttgat tcctgcaatt attttttttc gtcttctgag cttttcttct tttttcgata
    12661 gcgtcagttg aaatggttct tgtttcttta cactttccat aagcccctcc ttagttttgt
    12721 gaatgtttgc tgcttatgac ttcatgatag ataactatct gaattacgta tataatcatt
    12781 tttaccgtaa gtaaaaacgc ttacatagca atgatttttg tgctatacaa aacgataaag
    12841 tgtatttttt cacaaataaa ctacgcatag caaaccttct atttttttct atctgacact
    12901 tagcatagga aatgattata tacgtaatct ttcaccgatg ataaattgaa catatagaaa
    12961 cagaaacatt taatttattt tgaggaggag cctatctata tgaaaaagaa agtctctata
    13021 ggagaaagaa gttttacact tttcaacaat acgtttctaa ttttgctagc tttgatctgt
    13081 atcgttcctt ttttaaatat catcgctaca tcttttgctt ctacacaaga agtcgtcgcg
    13141 aaaaagttta tcctttttcc tactaccttt tctttagacg cgtatcgcta cattctttct
    13201 acgccgacca tttttagagc acttgctgtt tcgattggtg ttacaggtgt cggaacgatc
    13261 gtcagtatgt gtgcaacttc actgatggcc tacggtcttt ccagaaagta tttgtttggt
    13321 cgaggtttcg tcaactttct tgttgtattt tctatgttgt tcagcggggg gatgattcca
    13381 acgttcttag ttgttcgttc tctagggctg gtcaattctt actgggccat gatcctgcct
    13441 gtggctgtta atgcaatgaa tatgatcatt atgagaaact ttttccaagc cttgccggat
    13501 agtttggaag aatcagcaaa aatggatggt tgcacagatt ttggtgtatt tttcaaaatt
    13561 atgctgccat tagcgttacc gtctattgct actatctcgc ttttttatgc tgttacttac
    13621 tggaacactt atatgactgc tattttgtat atcaacgatt catctaaatg gccgatacag
    13681 attcttttac gccaaatcgt cattgtatca agtgggatgc aagcagaaag tagtgccgtt
    13741 gatgtgattc caccagcaca aacagttaaa atggctgtta tcgttattgc aacagtgcct
    13801 atgctgattg tttatccttt tgttcagaaa tattttgtca aaggagcact cgtaggttct
    13861 gtcaaagggt gattatgtac tgaacgcaaa atggtagttg tgtcagaagt ggtcagcttc
    13921 aagaaataag aaggcattta cgaaaattgc ttcttaaatt tttgtgaaat ttcggcttat
    13981 ttttcgaaga atctactcct ggaacaccgt gtatcagagg ttgtgaaaga gacgttcagc
    14041 cttgagcgat gataaaaact ctcacaaaca ttgcgacgag taacccacag gagcaataag
    14101 aagcgatttt gaaaaatagc ttcccatatt tcacaaaatt atgccttatt gtcgatagcc
    14161 tgtctcttga acgccattta ttcgtaaaaa agaactgtga caagactttt gtcacagttc
    14221 tttttgcgtg cttagccttg aaatttaact atccataaat acaaatacta gggttattct
    14281 aacttctttt attgcttgaa tcagtccaca agaaaaacag cctcttgatt cacaaatatt
    14341 tttttcgata ttctcccggc gtaatcgatt ccttcttttt aaagaaacga ataaaatttt
    14401 gcggatttcg atattgcaat ctttctgcaa tctcttttac ggagaggtta gtctctttca
    14461 accatttttt tgctacctct aaacgatgat tttgaacaaa atcaccaaat ttttctcctg
    14521 tttccttttt aaatacatta cttaaatagt tagggttata atgcaaccta tcagcgatca
    14581 catctaaaga cagatcacga tcatattctg tgtagacgat atgcataata ttctccgaca
    14641 aatttttaaa ttcatgatca gtgattgctt gagagcattc tgtgattggc agaactaatt
    14701 gttctaaaac aagtttttct agttctttgg gatgataatt gttcagtgct tttacataaa
    14761 tttgtttcat gttatcaaag ttttttgaat ctactcccaa taactgtcct aattgaacga
    14821 gttcattgat caagcggacc gaaactactt cccgactcaa aggattttta ttttgtgcaa
    14881 acaatgcatc aatcaattca tgtactaaat tcttcacttc ctgatttcca gaacgaatgg
    14941 cttcaaacaa tcgattttgt tcttctatcg gatatctaat aagtgttttt tcatgagcag
    15001 caggaacgat ttcctgataa aaaataattg aacttggacc agtatttaca cgataataca
    15061 gggcttcttt tgcccgatca accgattgct tgctttcatt cagcgtttcg aaccggttac
    15121 tgatgcctat actgatagtt aaattcaagt attcttttac acgtttttga atgagtcggc
    15181 aatactccat gacttttttg cttgcttctg catcatcttt atccattcga taaatagtgg
    15241 cttgcatttc ttcattcaaa acgatcggca gcattcgatt ttcctttggc acaatttccg
    15301 tgatcatgtt gttgatcgct aaaagtagca aatcacgctc cccaccgtga ctatcttcta
    15361 acagatcgat ttgaaccaaa gctgtataat agcagtcatt ttgagaacta taaccaaatt
    15421 gctgcaaccg ctgatctagt tctcgccttt ctactcgatt tctaaataaa ctaagtacaa
    15481 atagcgtttc cagctgtggc ttttgggtaa ctaagtgtgc acttaacgct tctttttctc
    15541 ctatgatccg actgactgat tgagcgacca aatctagttc tttcccactg aatccttttg
    15601 atttaagatt cagacgttcc tgtatttgag aaatcggacg ggcaaatctg tccgaaaata
    15661 agtaggaaag aagaccaatg agtcctacca gtgttaaaga cactgcaact agcccgattc
    15721 tcagattgcg gatcattgcg ccaattgcac tagagtcaac ttctaatctg taaatccaat
    15781 tattataatc tgatttcagt actatatacg ttttatcttt ttctcttatc actttcagct
    15841 gattgtaatc tagatccacg tccgttaata cagttggttg ctctttattt tttactgtct
    15901 gagtagtaaa aaggttgcca acttcgtttt caatagaaag tatgtcttct ccactttcac
    15961 caacaacttg ttctattgta tgtttctcta tcgtagcaat tcccaatgca tatttttctt
    16021 tttcaaacat tggcaaagaa atcaccattt cgattccttt gtttttcttt tgccaaaata
    16081 aattattttt gttatttatg tacttctgtt gatacttttc aatttcctct tcggtcagtt
    16141 gactcaacga tccattgatt actccccatt taccagccaa actgactaaa tcataattat
    16201 tatcatccat aacaatcgtt tctataaaat ttagttcttt cctgatttca gaataagtgg
    16261 agtaatctgt atatgtcagc ggatgcttga atatgtccga gaaatttttg gtcgaaccat
    16321 acgtagaaaa cgaatattca atcgttctaa ttttccattc aacgttagtt ttaacttgcc
    16381 tgagcaaatt ctttttgtct gttaaataac tcgattcgat cgattcatag gtattctggt
    16441 aaatgaataa actaaatcct atgacaagta cggctcctaa taaaaacatc ggtaaaaata
    16501 ttttataaaa tactgtactt ttcttcattt tcttcctctc ctccttttaa aataaaaggc
    16561 tttcattttt ctgtaaaatt gatactcatc taattaaatg agcattcccc gctttcaaga
    16621 atagcataat taaaaataaa aatccaagta atttttaacg tgtgcaatct tttcatatca
    16681 aagatctatt gacttatcgt agttatcgta atatgatgaa tgcgttaaca aaaagtgaaa
    16741 aagtaaggaa aatgatggaa tggtaacgat caaagatgtc gctaaagcag ctggcgtttc
    16801 tcatacgaca gtttctcgtg ctttgaataa cagcagttta ataaaaaatg aaacaaaaca
    16861 aaaaatacga caactagcta aggaaatgaa ttattcgcca aactatagtg caaaaggttt
    16921 agtgaatcaa aaaaaatatc taatcggact atttttctca agtttgcata aaggaacttc
    16981 atcaaatttc ctagcagatt ccattgcagg catccattca gtattagaca caaattacag
    17041 tttatctgtt gaaagtatcg atgttgttga tttaacagaa atcaacctgc aacgctacga
    17101 tggactgatc gttatgagtc aaagtgatga tgatcagcct ttcatcgact atctcaaaga
    17161 aaaagaattt cctttcgttg ttgtcaatcg tcacatcaat gatccagcgg ttatcaacgt
    17221 cactgccgat gatgcggccg gtgttatgca ggcagtagat tacggtattg gatgcggaca
    17281 tacgaagatc gcttatattg gcggaaagaa aaattttcgt tcgacaaaag aacgggaaaa
    17341 aggggtattg aaaagtctaa aaaaagcgag catccctgtc aatccagcct attttttaac
    17401 aggagattac agcttagaaa gcggcctcca aaacatggaa tacctattat cactttctga
    17461 cctgcctact ctggtttttt gcggcaacga cgacatagcg attggtgcat tgagagctgt
    17521 acatttagct ggcctccgtg ttccccagaa catttctctg atcgggttcg atgattctcc
    17581 agtcgtctcc tatctcaatc cgccgcttac caccgtacgt aagcctttga aagaaatgtg
    17641 tcaagaagga acaaagcttt tactagattt gatcgaaggc aggacgatcg aacaatctaa
    17701 aattgagctc tccaccttgt tgatccttcg tgagtcgatc aattacttgt aaactacaag
    17761 taattttata taaaaatgtt aacgtgtgca taacacagaa aggaagttta tatgaaaaaa
    17821 ctgacaaaag aattagtgaa aaaaaacgaa gcacctgtaa aagttcttca gtttggtgaa
    17881 ggcaatttta tgcgtggatt tattgattgg cagattcagc agctgaataa ccaacaattg
    17941 tttaaaggta atgttgcaat cattcaacct ttagaacaag gtcttggaaa tatgatgaac
    18001 cagcaagata atttatatac ggtcatttta caaggactca gcaatggcga aatcgttgat
    18061 acttccgaga ttatcaccgt agtagaacaa atgatcaatc cttatgatga atgggatgct
    18121 tatctatctc tagcagaaaa tgacgacttg gcctatatcg tctccaatac aacagaggca
    18181 ggaatccaat tcgtggagac tgataattta acagatactc ccccacagag cctcccgggc
    18241 aaactgacag cctttttata ccgacgtttc aaattaaaca aagctggctt taccatcatt
    18301 ccttgcgaac tgattgacag aaacggcgaa cgtctaaaag aaatcatttt acgctacgca
    18361 gaaaaatggg atttagaacc tgcttttgtt gagtggttag aaaaagaaaa tgttttctgt
    18421 tgtagtttag ttgatcgcat cgtcccaggt tatcctcgcg aagatgcagg tgttttcaat
    18481 caacggcata actatgaaga tcaattgatg gtcaaagcag aaccattcat gctttgggtg
    18541 atcgaagggc ctaaagaatt ggagaatcaa ctaccattca aacaggctgg cttgaatgtc
    18601 atcatcacag atgatatgac tccttatcgt gaacgtaagg tgcatttgct taatggaccg
    18661 catacagcga tggtccctct tgctttgttg gcggaattgg aaactgtaga agaagtaatg
    18721 aaagatcctt tattctccgc atatgttgat cagttattca atctagaatt gattcctatg
    18781 ctttctttac ctaaagatga attagccatt tatgctgacc aaatcaaaga acgtttcttg
    18841 aatccttttg cccatcacaa attagaagcg atttcattaa atagtgtttc aaagttcagc
    18901 acccgtctgc ttccagtgtt caagaagtat atcgaagaac aaaatcaggt accaccgtta
    18961 atcactgttt cactagctgc gctacttctt atgtatcgag gcgatcaagt aaagccacat
    19021 gatgatgaaa agacgataag cgaatttact gatgcttggt ctgataatgg aacagctatt
    19081 cctcgattat tgcaaaacgc tgcgctttgg ggagaagatt tgtctcaaat accgaatgtg
    19141 acagatacag ttcaagaaat agctgcaaag atcgatcaaa aaggtgtccg gtcagtatta
    19201 caagaaatga aaggaacgat ggtccatgct tgaaaccctg caaccaacaa tgaaattaaa
    19261 tcgacgagac agtgtggtcg tcgcattaac ccctattcca aaacaaacac aactgacgat
    19321 tgatcagcaa acgatcacca ctcttgaaga tatcccgcaa ggtcataaga ttgcattggg
    19381 tgatttgaaa gctggagaca acgtgatcaa atatggctat ccaatcggtc atgtgacgac
    19441 agacgtaact gccggtcaat ggctgcacac tcataatgta aaaaccaatc tttctggtga
    19501 attggattat cgatatgaaa aagatgtcca tccaagtcat tacctttttg agaaccgaac
    19561 atttcaaggt tacttgcgaa aaaatggaaa agtagggatt cgtaatgatt tgtttttagt
    19621 acctaccgtt gggtgtgtga atggcattgc tgaactgatc gtcaaacagt tcaaggaaaa
    19681 acatccagat ctgggacagt ttgaccatat tacgatttta aagcatcctt atggctgttc
    19741 gcagcttgga aaagatcatc aaaatactcg agaaatttta gcggacgcag taaatcatcc
    19801 caatgccgga ggagttttag tatttggatt aggttgtgag aacaatacag ttcctgaatt
    19861 caaaaaaatt ttaggtgaat atgatgaaga acgagtgaaa tttctagtgg ctcaagatgt
    19921 ttacgatgag atcgaacaag gtgtggctct attagaagag cttttaacag cggcggaaaa
    19981 tgaccagcgc atatcagtcc cgctctctaa gttgaatgtc ggtttgaaat gcggcggttc
    20041 tgatggtcta tcgggaataa ctgctaatcc tttacttggt gcattttctg actacttgat
    20101 tgctcaagga ggcagcacga tcttaacaga agtgccagaa atgtttggcg cagaacaagt
    20161 attgatggca cgagcggaaa atgaagaagt ttttgactca atcgttgact tgatcaatga
    20221 cttcaaacag tatttcttgt cttacgggga accagtttac gaaaacccat ctcctggtaa
    20281 taaagcaggt gggatcacta cattagaaga taagtcttta ggctgcacgc aaaaatcagg
    20341 aagctctcct gtcgttgatg tgctacaata tggcgaaaaa atcagaaaac cagggcttag
    20401 tttattgcaa gctcccggga atgatcttgt agctgcctct gctcttgctt catccgattg
    20461 ccagttggtc ttgtttacca caggaagagg gactccgttt ggctcatatg tcccaacggt
    20521 caaggtatct acgaatacaa ctctttttga acgcaaaggt cattggatgg attttaatgc
    20581 aggcgtctta ttagaacaac caatggaagt aatcttagaa tcgtttgttc aaaaaatcat
    20641 cgctgtagct agtggagaag aaacgaaaaa tgaacaaaat gacgttcgag aaattgccat
    20701 ttttaaaaac ggagtaacac tttgattttc ataaaacagt ataaaaagaa agaaggaaga
    20761 tttatgtttt tatctgatga ttttttatta aaagacgatt gggcgaaaaa gctttaccat
    20821 tcctacgcaa aaaacatgcc cattattgat tatcactgtc acttagatcc aaaagaaatt
    20881 tacgaaaaca acaatttcag caatctgaca gaagcttggt taggaggcga tcattacaaa
    20941 tggcgcttga tgcgagcttg cggcgtgcct gaagaaaaaa tcacaggaaa tgcttctgat
    21001 tttgaaaaat ttttagcttg gtgtcaaacc gtaccaaaaa ttatcggaaa tccgctttac
    21061 agttggtcac atcttgaatt gaagcgtttc ttcggtattg acttgttgat aaatgaagaa
    21121 aatgcagaga aaatttggac acaagcaaat gaaattttgg cagctcctga ttttcgccgt
    21181 cgggaaatcg caaaaaaatc gaatgtagaa gtgatttgta caacagatga tcccgcagac
    21241 gacttgcact atcatcagtt gcttgctcat gaagaaccag atttgaaggt tctaccttca
    21301 ttccgtccag ataaagcact caatattgaa aaagaaggat ttaatgcatg ggtcacacta
    21361 ctggaagaag cagctgacca aacgatcacc acctatcaag aactgataga agtcttaggg
    21421 cagcggatag aatacttcca tcaacatgga tgtcgtgttt ccgaccacgc tttagacatc
    21481 ttacgctata aagaagcgga tgaaacagta ttagaagaga tttttcaaaa agcacgagct
    21541 aacaaactat tatcttcaga tgaaatcgat gcttatcgta cagaaacact gatacatttg
    21601 acccacttct atcattctca taattggacg atgcagctgc acatccatgc ttatcgtaac
    21661 tgtaatacac aaatgttgga aaaattaggg cccgataccg gctatgatgg aatgaatgat
    21721 ctttctttga ctattcctct gcaaaaatta ttgaaccgtg cagaagaaac ggatcagttg
    21781 ccaaagacga tcctttattc attgaatccg aatgactatc ctgcgatttt agctttgatg
    21841 ggctgtttcc aaaaagaaca gaatggaaaa ctgcagttag gttctggatg gtggtacaac
    21901 gatactcgag ctggtatgcg cgatcaattg acacaatttg ctgatggtag tgctttgggg
    21961 aattttgtcg gcatgctgac agattcaaga agtttcctgt cctacactag acatgaatat
    22021 ttccgtcgtg ttctttgtga atttttaggc gaaatggtca tgcgaggaga agcacctgaa
    22081 gatgaacaac ttttaggaag tctagttcaa gcgattagtt atacaaatgc taaaaattac
    22141 tttggctttt ttgcctaatt gattaatagt aacagtaacg aatcaaaaac aggatagtga
    22201 aataacggaa tccgtttatc cacgttttag agaagaagac ggaccaaatt tgctccgtct
    22261 tcttctcttg ctgttctgct tcattgccta taaaccttta tgaaagaaga gataacatgc
    22321 ctactatcca tattgccggt gattctactg cggcagaaaa agatgaaaac aagcgtcccg
    22381 agacaggttg gggagaaaaa atctctgctt atttttcacc cgagatccag atcaataacc
    22441 aagcaaagaa tggacgcagc accaaatcat ttatccagga aggaaggtta gcccgtctag
    22501 cttcacagtt tcagccgaat gatttcttat ttgtacaatt tggacataac gaccagaaaa
    22561 tccaagaaga aagaggtacg cttcccttcg gtagctattt aaaaaatctg cagatatttt
    22621 ttgaatgcgc aaaaaaagcg aacgtccaaa tggtcttact gacatctgtg acgcgacgag
    22681 attacttaga aaacggaaca ttgaatccag atatacttgg agactatcca aaagcgatgc
    22741 gtgcatttgc tgagaaacac catattcctc ttttagatgt gttctcaaga tcacaagaat
    22801 tgttccagac cttctcaaaa gaagagacaa aaaaattcta cctgcatctt atacctgata
    22861 cttgtaaaaa ttacccagaa ggactaaaag acaataccca ctttagtcca gaaggcgctg
    22921 ataaagttgc ccgaataatt gttgaattga taaaagaatc ccgtctgcct cttgctaatt
    22981 atttacaaaa aggagtttga gatgtttcca ttaaatttag gcatccgtgc ccacgattta
    23041 gatgttcgaa atcgtgaaga aatcgttcaa aaagtatcac agcttcactt gtcccatatc
    23101 caatttgcac cacaaaaagc atttcctgaa caacttaaat taactgacat gacacttggg
    23161 agtgctgcct attttggtga atacttccaa aaaaacaata tcgaactttc cattttagga
    23221 tgctatatca acctatccag caaaaatcaa gaagttcgtg cacaagcatt ggcaactttc
    23281 aaacagcaaa ttgctctgtg ctctgcctat caagccaaga tgattgctac ggaaaccggt
    23341 agtgtctctg tcggttacac aaaagaaaat tttactgaag aagcttatca gatcgccaga
    23401 aattctatca ttgaattagt cgctcatgca gaaaattttg gcgtaactgt tgctgttgaa
    23461 gcagggatca atcatccaat ctataactat cagttagcta aacgtttaat cgatgaagta
    23521 gcttcaccaa atttaaaaat cattttagat tgtgcgaatt tgatgcataa agaaaatcat
    23581 gctgatcagg aaaaagtgat ccgaggtgcc ttggacaatt tacatggtta tattacagcg
    23641 cttcatctca aagactatat catggaaaat ggaaagatcc gcatggtacc tgttggcaag
    23701 ggctgtttag atttccgccc ggtactgcat tatatcaaat atgagcgtcc tctaatgtac
    23761 gccactcttg aagctactcc tgagatttat gttcctgaag caatagaaca cttgcagttt
    23821 atttaccaag attgttaagg agaagattat ggaggaacga atacagaaaa gttatcaaaa
    23881 atatcatgca aatgcttttc agacattgct gcatctttat cagggaaatt attggcgttt
    23941 tgccatgtca ggactctttt ttattatcaa acatcttcca tcttggttaa tgccgatcgc
    24001 tattgccaat gtaatcaatg cagcttcatc gaaagattct tctcagttgc aggccattta
    24061 tttcaacgct tttttgatgg cttgtctgat tggtcaaaat atattgacga attattttca
    24121 tgtaaaatac catagcactt cgatccgtca agtagaagct ggactaagag cgacccttat
    24181 caagaaaatc caagaactat ctattcctta tcaaaaagaa ttgcaatctg gacgaatcca
    24241 gtcaaagatc atccgtgatg tagaagctat ccaaacgttg tcctctcaag tatttgtcag
    24301 cggattaaat atcgctgtca atttattcgt agctttaggt atcacgcttt ataaaagtcc
    24361 tgttgttttc atgtttttct tattgactgt tcctctcgcc gcattcgtta ctctcttttt
    24421 ccgtaaaagg atcagacagt ccaactcaga cttcaggcaa gaaatggaag agacttctgc
    24481 aaaagtgatc gaagtgatcg aattagcacc gattgctcga gctcatgggt tagaaaaaca
    24541 cgaaacaact cgcttaaata agcattttac tcaaatctat gaaaaaggat tccacttaga
    24601 tatcctgcaa tctgttttcg gatcagtcag ctgggctagt tttcagatat ttcagctgat
    24661 ttgtttgatt ttcactggga tattagcttt acaagggcgc atccaacccg gcgatgtcgt
    24721 gatgtatcag acgtatttca cgacgatcgt caattccgtt tctggaatga tcacgctgat
    24781 tcctacgatt tcaaaaggca tggaatctat cacttctatt ggcgaactgt tgattgctgg
    24841 cgatgtagaa acttatcacg gtaagaaaaa aatccaacat ttggatggaa attttcgttt
    24901 tgaggatgtt tcttttcttt atccggactc actcaaaccg attatcgatc atttttctct
    24961 agaggtgaaa gctggagaaa caattgcttt tgttgggcca tctggctctg gaaaatctac
    25021 actccttaac ttattgattg gatttatcca gccgacttca ggaaaaattt ttctagatga
    25081 tcagcctttg gatgaactgg atatgcgaag tgtgcgaaat tatttagccg ttgttcctca
    25141 aaccactttg ttgttctccg cttcgatcaa agagaacatc acttatggct tgaaaaacgt
    25201 atcaaaagaa cgtttagatg aagtcatcga agctgcgcaa ctttcttcac tgattgacca
    25261 gcttcctgat ggtctggata ccttagtagg cgaacatggc aacaagctgt ctggtggcca
    25321 aaagcaacgt atctccattg cacgagcgtt gatacgtcag ccaaaaatca ttttgctaga
    25381 tgaagcaacc tcagctttag ataaccagtc agagaaaaaa atccagcaag ccctgaatta
    25441 cctgacagaa acacccacta cttttattgt ggctcatcgg ctttcaacga tcaaagaggc
    25501 agataaaatc gttgtgatcg atgaaggaaa aatcgttgaa ataggtactt acgaaaaact
    25561 gttagctcaa aaaggctatt tctaccgctt gaaaaatgaa tgacaaaaaa taggagctat
    25621 gacaagactt ttgtcgtagc tcctatttct gaataaacgg tgttctcctg ccaactcctc
    25681 ggtcacaagt cacaatagtc atcaaacatg agaagctgtt ttttgaaatt gttccttgta
    25741 actcagagtt aaacggtagg ctcacgacct cttggtaaat ggtgttcaag agacagccta
    25801 tcggcaataa gaagcaattt tgtcatcgct caaggccgaa cgtctctttc acaccctctg
    25861 ttgtttcata aaatagtttt attcgctgta aaggtcgcga actggtgtca tgatgatacg
    25921 gttcaagtca ttgatgattg tactgaagcc ttgctctttt tgcatcaagt cattgattac
    25981 ttcttctgat tggattttca cagccatttc ttgtgctttc attgcatctt cgtcgctgaa
    26041 ctcttgtcca ctcatttgtt tttcttgtaa ttcgatttgc atcgcttgga agtctttgaa
    26101 cagtttgtgt gcttcttcgt ttgcttgtac tttctcgtac gcttctttca acgctttgaa
    26161 ttctggtaat tcacggatct cacgttcgat ttgattcgcg ctatcgtaga tgtttgacat
    26221 gttatgccct cttttctttt agtagttact ctctattgta acatggggtt attcgttttc
    26281 aaaggggcta ctctccttga tatttccgcc agaggtcttt agccgcttca ccaattccct
    26341 gaacgccttc tttcaccata tcgccgaagt ttttcagccc ttcttttgct tgttcaccat
    26401 attgattcaa gttatcttgc caatttccag actctccatt agaatttcct gtgtttccaa
    26461 cttgatctgc agctaccact tgtcctcctg tggcataggc atctgctaca ctaaatcctg
    26521 tttttgaagt atacggaagg atgccttctg ccgctgattt gaagactttc ccgacaacat
    26581 ttccacttgt cccttccaaa tagtgcagct tgctggattc ttcgtaaccc atccatgtcg
    26641 aaatcactac gtctggcgtg taaccgatca tccattggtc atttgctttt gtggcatcga
    26701 aattagtttc tgtggttcct gttttccctg ctatcgtata acctgcagga ttcgcagcag
    26761 ccgctgttcc atttgaaaat gtaccaagaa gcatgctggt catttcatcg gctgtttcct
    26821 ttgatatgac ctgttttggt tttttgtttg tgttatcgac gatcaccgct ccagtcgaat
    26881 caacgatttt cgtgataaga tgcggcgtat acatctgacc atcattggca aatgcactgt
    26941 aagcacccgc catgatcaat ggagatactc ctttttccag tccaccaagg gctaagccat
    27001 aatacttatc agattttgct aaaggcaggc cgaattcttc tgctttatca tatccttttt
    27061 gtaaaccgat ctcatgcaaa agccatacag taggcaaatt caaactttgt gcaacagctt
    27121 gatacatcgg tacttctcct tggtatgtcc cgtcaaaatt atgcgcatcg taataacttt
    27181 gcggttcgtc tttcaagata ctggaaggct tgtatccagc ttccagtgct ggtgtatata
    27241 cgcttaatgg tttgatcgtt gatcctggtg aacgacgcat ctgtgtagca aagctgaatc
    27301 ctctaaagac atgatctcct cttcgtccta ctagtgcttg tacaccacct gtattcggat
    27361 ctaaagctac tgaagcagat tggaccatgg caccatctga agcatttgct gggaataatg
    27421 cactgttttg ataagtagct tctaattgct tttgataatc ctgatctaaa gctgtataga
    27481 ttttatagcc tttattcatg acatcttctt catcaagacc atactcgtta actgcttcat
    27541 cgatcactgc atcaaaataa taaggataac gataaccaga atctgaatta tcgtatgtgt
    27601 cattaagata cgcgctgata tctgtctggc tttctgcttg ttcttgttct tttgtgattt
    27661 ttccgttttc ttccattaca cttagtactg tgtttttccg atcattcgca ttttttgggt
    27721 gatcgatcgg attataaata ccaggacctt tcagcattcc tgccaaagta gcagcctcag
    27781 acagcgtaac attcgttgca tctactccaa aatactttct ggaagcgtct tggacacccc
    27841 ataccccgtt gccaaaatag gcattgttaa gatacatggt caagatttct tctttgctgt
    27901 acttcttttc gatctcgatt gccaaaaata attccttcgc ttttcgatca aacgtttggt
    27961 ctaatgtcag atacgcattt ttggcaagct gctgagtgat cgtacttcct ccgccccctg
    28021 atgttccgcc agacaagacc attcggactg ctgcacgggc aatccctttg atatcaaacc
    28081 cgtgatgctc gtaaaaattc ctatcttctg tcgagattac tgcatcttgg atatagggag
    28141 aaatcgcgtt taattctaca tatgttcctt tttgggcgta cagtgtgcca gcttcttcgt
    28201 ttttcttatc ataaatgact gtcgattggc ttaatcctga ttttaacgtt tcgacatttg
    28261 cttgttttgc taaaataaag aggtagatac ttgtcactaa gacacagatc aaaccaatca
    28321 gcaaaatcaa tttgttcaca tgatattttt tccagatgcg ctttcgccat cgatggaatt
    28381 gtccgagata tggtctgatc caacgccaaa aactgatcaa agcagctttt atcttttcta
    28441 aaatgctttg aaaatccatt tgcttcttct cctgtctatt tgattcaatc gtcttatttt
    28501 accatagtga aagagtgttt tcttcctgct taagttgtag ttcaatatgt ttttttacgt
    28561 tagtgcaagt agagtaacat aagaatgaac agaaaaatgt aagttttttc ttaaatatgt
    28621 tttaaaaatg gtacaattag tctgcgattg cactgaaagg agtacacttg tgaaaatcac
    28681 gatcacttta cctatgaacc atcctgaaac aacaattcgc gacttgcttg aaaaggaatg
    28741 gttagttcct agaaaggttc gacacttttt gcgtatacgt aaaaacgttt ggatcaatca
    28801 acaacctgct ttgttccatc atgaagtaaa gggcaatgac cagatcacat tgttattcga
    28861 agaaacagat tataattatc aagaagttca attaggagat gcgaagcaca tccgtgtttt
    28921 atatgaagat gagcatttga ttatagtgga taagcctgca ggaatgaaga ctcatccaaa
    28981 tgaaccgaca gaaaacagta ccttactcaa tcatttagct gcttatctcg acactaaaca
    29041 gcaacgacct tacgttgtcc accgcttgga caaagaaaca agcggtgccg ttttatttgc
    29101 aaaaaatcca tttgtcttgc cgatacttgg aagaatgttg gaacaaaaaa tgatctatcg
    29161 gagatatcaa gccatcgtat ggggagaaat tgccaaagat atgaccatca ccaataaaat
    29221 tggacgagat cgccatgatc ggagaaaaag ggtcgtagat gataaaaatg gtcagagcgc
    29281 cttgacacat gtcactgtca acaaagtact ttctgaacaa acacaagtct attgtgtttt
    29341 ggaaaccgga cgtacacacc agatcagagt tcatttagct cataagggac atccgatcgt
    29401 tggagaccct ctctaccaaa atagaacagc tgaacgactg atgctccatg cattagaact
    29461 gcacatgatc catccattta ctcaagaaaa aatagtcggt aaagctttac ctggattatg
    29521 ggaatagaaa taaaaaagaa cagagtctta tcagcagata atgataagac tctgttcttt
    29581 ttgtgtaatt tgtctgctta cttttgatgt tcgtgttctg ctaacagcaa actaccgata
    29641 atcccacttt cattcggcag tccccaacga acgatatatt cacttacttg aggtgtttcc
    29701 atataaccac ccatcaattc aacaaattgc tgacggattt tttgaaggag atgatcctga
    29761 ttcattaccc caccgcctaa aataatcttt tcaggtgcta acgtcaacgt atagttgatc
    29821 agtgcttgag caatataata agcctgaata gcccaaacag gatgatcttg cggcagatct
    29881 tgccctttga tccctgtgcg tgcctcaata gacggtcctg ctgctaatcc ttctaaacaa
    29941 tctttatgat aaggacaagt accttcataa tggtcatctg gatggcgttt cacccaaata
    30001 tgtcccattt caggatgtgc gatccctgaa aaaatttctt cattgatcac gacacctgca
    30061 ccgattcctg ttcccacggt aaggtaaata caactatttt ttccttgtgc tgctccttgc
    30121 ttcaattccc catatgcagc agcattgaca tccgttgtcc aagcagcagg aatattgtag
    30181 cgttccttga ttgtgccaag aaaatcgaat tgtgcccacc cttttttggg agttgccaaa
    30241 acgtatccgt aattatcttt tgttttgtcg ataccaatcg ggccgaatga gccaatcccg
    30301 attcccttca attcataacg atcaaaaaat tcaaatacct gatccaatgt ttcttctggt
    30361 gttgtggtag ggatacttaa tttttctaaa atttctccac catctgaaac cgcacacaca
    30421 aattttgttc cgcctgcttc tattccgcca tacattcgtt ttcctcctcg aatccgattg
    30481 tccgaatctc ataaggttgg attattggga caaccgcttg cttcgttggt tcttcaagca
    30541 gattcaatat gacagttttt ccattgtctt tagttatttc caatttttct aaatgactag
    30601 acatattgaa acctcttact actactttat cactaaactt gctgcgtttc aaagctgtaa
    30661 ttgcaaacgt ttcacttttt atcgttaaat attgttgttt tgaaatcaat gttccttcat
    30721 gatgtttgat ttgttgagtg gaaaaaggaa tctgtgctgc gtatgcatgc aaataagtag
    30781 agaatttttc ttctggtcca tgtagttcaa tgctgtaatt gaaccgatgc tcacctagac
    30841 actgtgcttc tggtgttgga aaatatcccc aatcgcctag ttctcccaca ctgcgaagta
    30901 gcgtcactgc gatttgtccg tcttctgtta cttcatattc attcaaacca aagtttccga
    30961 ctgttacacc gtactcttca tcatgaatat tgacaaatgc ttgctgatgt tgcggattcg
    31021 tggggttttc ccaactttta gacacatggt ttgggcgctt caccacttca aaaatactat
    31081 ctgcttcgtg atgttccaca tgtaactttg taggaaacaa gacacgtaag cgatgatctt
    31141 tcatctgatt gtcgagagtc gtttcaaagt cgattttttt actatctttt ctgattgtca
    31201 tgattgtttt tatttgaagg attcgttttt ctttggatcg ttctgctttt cgataacgaa
    31261 attccacaac catctgctgt tctttttcta aacgctcgtc tgcagaaaca gggatttcca
    31321 tttcctgtag aatacttatt tttgctattt ccggtgtatc tactaatact tttacttcag
    31381 agttttcttt gttactggat aggattggct gatcacagaa aggttgttta aagatatact
    31441 catttcctat atcgccgata tcttcaaaaa tatgcagatt attcaacttt cgtttgtttt
    31501 tgcgatcttc cattgtaatg gtaccatttt tttcaatcgt caaatgtaga gggccgtttt
    31561 cgatgattcg tccactctga tgaatcattg tttccttttc ttctgctttc gcttcccctt
    31621 ctacaagcgc gaatgtttcc caagaaaatg ctggcatgtt ttctaatggt aaagtcactt
    31681 tgatcattct tgccatatat ggcacacgga aacggtcttt cggcaaatca taaccaaatt
    31741 ggacagtttc ttcagataaa atagctggta tagtggcccc actttttgtt tctacatgat
    31801 acttacgttt aggcaaattt tctaactctt gatatagttg ttcaggtatt ccttcagcga
    31861 atctttttct ttctaattcg atggttattt ctgcttcacc agttttatcc attcctgcag
    31921 tatttacaat gacaaatgga aagctgtctt ttgggaatcc ggtcgtatcg attgctgcgg
    31981 tcagctgttc taaggaatct tgtgcaagat actttccaac ttcatctgct ttttcaaaac
    32041 gaggtatcat ttcccgatgg acagaatcga ctgaacaacc gcaaatactg tcgtgaggat
    32101 gattttgcat taatgtcttc caagcataat ctaattgatc atggggatag tttccactaa
    32161 cttcataagc catcgtcgca agtggttctg taatattttc tagctgtcgc tggaccttgg
    32221 tattccattg ttttaagtaa acccgagcag atgctgtatt ggctaaagta taccagccat
    32281 ccgtttcttg acttgtcaat tctccttcta ctgagcctaa gtcttctggc acatcttttt
    32341 gaactgcttc cagatagtca gtaaaattag aatgaataaa ctcgtaatct ggaaacagtt
    32401 catttgcgag atggattgct tttgatatat ctttttgtac cggttgatga tcaacaccat
    32461 tcatcatcaa taagtggttc gtagaggcat attgttctgc atccgctaat ttttgcttcc
    32521 aaaaggcaag agctgcttct ttttctactg gaatctcatt cccgttgcta taccaattgg
    32581 caaatagcag accaaagatt gctgtttgat caggtccttt ccaccacatc tctgagtatt
    32641 gggaagaata gttttctgct tccaaaactt gattatcaaa gccaattggt tttacaccac
    32701 ggccaaacgc tgctgctgaa ataccagctt gtttcattaa ttgaggcgtc tgtcccatat
    32761 ttccaaatgt atcgggaaaa tagcctaaca tgacaggggt tccccattta cggctttctt
    32821 ccatgccaat cagcatattt ctcacgttcg attccgagct gataagaaaa tcatcttgca
    32881 agatataaaa tggtccaatt ctcaattttc cttcattgat tgcttgttgg attgcctgtc
    32941 ttttttctgg ccttacttga agatagtcat ctaaaataat cgtttgccca tccaaatgaa
    33001 aactgttgaa ggacggatca acttcaaata gctctagtag atcgtctatc aattcaatca
    33061 gtcgcatgtg atgctgttcg taagccatgt accattcacg atcccagtgg ctatgagaaa
    33121 tgatatatac tttctttttc atttacgata cctcctactt ttctactcta atatcaaagt
    33181 aatccatgac taattcgcaa aacatcatat ttgcccaaga aaaccattct ctcgtataat
    33241 tttcaggatt gttcacatcg aatccttcgt gcataaggtg tgttcctgcg tcagttgcta
    33301 caagtaaatt caatatccgc tctttttcag atttgtctga cgttgtcatt ccttccatag
    33361 ctaatgcaat cggccaaacg tatttttctg gcgtatggga ggatccaatt ccttttgcgt
    33421 actttccttc atagaaatat ggattttctt tactcaacaa tgttcttctt gtttgcagat
    33481 aatcttcctc ttgttcagaa caatatccca agtaaggtgc ggcgatcaga ttgggcacat
    33541 tactgtcatc catgactgtg gcgtttccca ttccatctac ttcatatgca taaatcgttt
    33601 gccctttttg attaaccgtt cgtccgtgat tctgaatccc ctcttggatc tctttcttca
    33661 atttctgtgt ttgctgtaca atttctttat catcgagtat cgtttgaaaa atttcttcca
    33721 cataacctaa cacgaccacc gcaaacatat tggatggtac cagatatcca taacggcaag
    33781 tatcatcgct aggacggaaa ccagaccatg tcattcctgt aaaagctgtt tttgcacctc
    33841 gcccgtcatt gatcagcgta tcttcttttc ttgtcgtgtc tcgtacaaat gtataaggag
    33901 agtgttcatg atcttgctct gttttgaaca cgtccaagat ttttttgata ccttcaataa
    33961 aagattgatt gaattgatca gtttttcctg tatttttgta aagaagatag gccaactgta
    34021 ttgggtagca taaagaatca atttcatatt ttctttccca gatccaatcg ttcatttttg
    34081 tatgatctgt ttggtggcca gcaccgttag cttcttcgtt gaaggcattc gcatatggat
    34141 cgatattgat ataaaaaaat tgctttttga ctaacccgct gatcatgtca gctaattcct
    34201 catcttcttt tgcaatcact aaataaggac gaacttgtgc agtagagtct cttaaccaca
    34261 tcgctggaat gtctcccgtc aataaaaagg tggttccgtc attttgcttt ttgactgttg
    34321 tcaacagagt attggcaaat gctgctgtaa aattctttgc ccagtccgca tggatatccc
    34381 cacatttttg tgtgatatct tccataaatt tctgcaccga ttttggtata tctttataag
    34441 ccactaataa aaccttcttt ctatttgata tatctttaaa gattatactt catacagcca
    34501 attatgtcta cgctttcaaa aaatatcttt ttatttactt tttcatccat tatggtatta
    34561 tttgaatatg atatatcatt aagaggtgtt tatatgaatc aaccattgta ccagacaata
    34621 tttaatgatt tgcaaacggc tattttaact ggtgaattac ctgtagacag ccaactacca
    34681 actgaaaaag aactttcacg tacctataaa gtaagcagaa tcacttccaa acgtgcattg
    34741 actgaattag agcaattagg acttatttat cgcgttcgcg ggaaaggcag tttcgttaaa
    34801 tccgcttctc cggaacagat tcttgcttct cctacaaaaa cacgacggat tctgtttctt
    34861 cttccatatg tcgctgattt gtctgttggt gattttagca agggattgaa ccctgtgatg
    34921 caagataaac agattgatgt catgatgacg acgcttgact ttctacaaaa taaaacagca
    34981 aaagagctaa tcaatgaatt tgacggattg atttattatg ctcttgatac agaacaacat
    35041 cttgacttac tttttgagct ttcattgaaa gaattccctg tcgtcatatt agataaaaaa
    35101 atctatgagt taccttttcc taccgttctt tccgataatt tccaaggcgg tgcgcttgct
    35161 gcctcttatt tgatcgaaca gggacattca aaaatcgctt atttgtttgg tacgcagact
    35221 catccacaat ccgttcgaca gcgttacctt ggttaccttg aagcattgga caaagctggt
    35281 ttgactttcc acacttcact ggatgacaaa agcgcgacat tagatgaatt gctttcttat
    35341 atcactaagt atgaagtaac tgcttttgtt tgtgaaaacg atgttgtcgc tatccagacc
    35401 atgaatctct tgagacagca tggttatcat atccctgaag atttttcaat tatcggattt
    35461 gatgatatcc aagcagcagc tcttgttgac ccgccactga caaccatcgc acaagatttt
    35521 gaacagttag gtaagcttgc gggagatgct ttggtcactt ggttagagac aaaagatcga
    35581 ccatccgata gtaaatttcc agtttcattc atcaaaagac aatcaacaaa ggagaaataa
    35641 aatgaatatc ggtcaaatag atactagaca tgcaacagcg aatcagccaa atttctctaa
    35701 tgggaactgc cagccttata ctggcgttcc ttttgggatg aattattttg caccgcaaac
    35761 tacggatcaa aacggcagct ggtggtttca tcctgatgac cgcgtttttc aaggctaccg
    35821 tcttacccat caaccaagtc cttggatggg tgatttcagt catatgctgt ttacgccgat
    35881 caatggaaaa ctacaggaga acaccctttt ccatgctcaa agttcttacc gcccagaaga
    35941 aagtatattt tgcccgactc atctgtcgat ctgtcaatta cgttatggca tctgttctac
    36001 attgatacct agcatgtatg gcggaatctt atctattgat tacagcaaaa atgacagcgg
    36061 tttactttta tcctttccgg gacgccatca gctctttgtt atagatcctt acacagtgga
    36121 aggaaaaatc acacattttg ctggttcaga agatcctgat ttttcttttt attttatatt
    36181 gagatttgaa tatcctttaa caattgatga gttagctgtt tccaacaaaa atagcgactc
    36241 gatcccgttg tattttgaac agacaaaaaa acaaactatc cgatttggga catcttttat
    36301 cagctcggaa caagcagctt ataacctgga actagaacaa aaccaaagca aagagactta
    36361 ccttgctcac agtcaagaac aatggcagtc ctattttgat cgtatacagc tcacacacca
    36421 tgatcaacaa caattgcgga cgttttatca taatttatat cgggtgtttt tatttccaca
    36481 aacattttat gaaattgatc ctagtgggca aaaaatccac tatgatacga ctagtcgatc
    36541 tataaaacct ggtgttctct atacaaataa tgggttttgg gatacgtata aaacggttta
    36601 tcctctttat tctttgattg ctgtagaaaa atacgaagaa atgctggaag gttttttgaa
    36661 cagctataga gaaagtggct atttgccaaa atggctgtct cctgatgaac gtggacttat
    36721 gcctgggaca ttgatcgatg cggtcattgc agatgctgct gtaaaagata tccgacgaga
    36781 cttgatgcct gaatttctaa cggcaatgga aaaaggtgct acggttcaaa gcaaacatcc
    36841 aaattatgga cgccaaggaa cagaagatta cttgacatat ggctatgttc ctaatcacta
    36901 ccacgaatca gtcaatcaca cattagacta tgcttatagc gatttttgta ttagccaagt
    36961 tgccaaggta ctagaagaag aggaaatgac gaagaaatat cagcagcaat cattgaacta
    37021 tcaaaatatc tttgactatg agtcaggatt tatgcgttca aaagataaag atggcaagtt
    37081 cagagaacca ttttcagcta atcgttgggg acaagattat gcagaaggaa gtgcttggca
    37141 aagcagcttt gctgtttatc acgatttttc aggactgatc ggaaaatatg gtggcagtga
    37201 gagatataaa gaaaaactca ttgagctgtg caatcagccc ccaacgtttg acccaggagg
    37261 atatggtttt gagatccacg aaatgagtga gatggccgcg atagaatttg gacaattagc
    37321 tatttcaaac cagccaagtt ttcactatcc ttacttgttc agttatatag gacaacctga
    37381 aatggcacag ccactgctta aacagttgat gactcagacc ttcgacgatt ctccaatggg
    37441 ttaccctgga gatgaggaca atggaagtat ggccgcttgg tatatcttca atagtctggg
    37501 attttatcct gtcacgcctg gaaccggtga atatgttatc ggtatgccat taattgacaa
    37561 ggctgttttg cttttgtcaa atggaaagga attgacgatt gaagcaacgc ctaatcggcc
    37621 gcagcaacaa tttatccata aaatcaaacg gatggacaaa gaatatacga aattatattt
    37681 tacccatcaa gatttgctga aaggcggcac gatctcttac caattaggga tcatccctca
    37741 ccctaagaaa tatcaagcaa aagatttgcc tttttcctta tcaaactata attaacaaga
    37801 ggttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaagcaaaa atagatcctc
    37861 atatttttcg tttggttggt cttattaccg cagatgcaag cttttgaaca ccgtttattg
    37921 agaggttgtg aaatcagcgt tctgacctga gtattagaga gacaaatggc aaaatagttc
    37981 ctcatatttt gccatttttt gagctaatac cgagggtcag ctgattgaac accgtttagt
    38041 ggagaggtcg tgaaaaagct gtttagtttc gagtattaag aaaaattttg tgaaaatggc
    38101 tttccacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg aactccgttt
    38161 atcgagaggt catgaaaaag ctgccttgcc tcaagtaata agaacagccc aaaattagat
    38221 ttctagacaa ttttttataa gttatttcat tacattggct ttttctttta tgattctcca
    38281 ctgttttctc ggtactcttt aggggatctg ccgacgattt tcttgaataa tttagagaaa
    38341 tacgtggtgt tgttgtagcc aatctcactt gctatctcat tgatgttttg attactgtgc
    38401 aaaagcagtt gtttcgcttt ttccatacgt aaatggttca aataagctga aaaacttttt
    38461 ttcgtttctt ttttgaacag ctgtcctaga tacatgacat ttaaatgcag gttttctgac
    38521 acttctttga gtgtaagtgg ttcttgataa tgctggtgca ggattacgat tactttttcc
    38581 acattgtcac tgtacttttt ctgtctctga tgctttttga tgaatgacag aagtagctgc
    38641 tgaagttctt gcaccgtttt tgcctgatgg attttttcga ttccttgtaa atattcctca
    38701 tcttccagat caatcaattc ccgttgaatc tccataaaca gtaaaaaact ggaatatcgt
    38761 atatcttccg gcatcatggc tgctaactga aactgttcaa aaaaatcagt gatcattttt
    38821 tgagcgactt ccaattgttt attttgcagc acgcgtctga aacttgaaaa atcgatggtt
    38881 tgatcttttg tttctgcttg tactgcgtaa aaaacatgct cgtctttatc tccataaaat
    38941 tgatgcaact gtagattgtc tttcgcttgt tggaatgttt cagggatttt gtccaaagaa
    39001 tctgtctctt ccccgatact gatcagccat tcctgatcag gaaagttttc ttgaacaaaa
    39061 caacagaagc catcaacttc atctgcctcc aacaacaacg tgatcaatac acggtctccg
    39121 taatttcgtt gatagtaaaa gatttgttgc cgttcttgca accatctatt gataagagta
    39181 tcatgagttc ttgccagttg aatcaatact atcctatgct gcttctcact tatttgtcct
    39241 attatttctt cttcacttat ttcatccaat tcttcattca accattgact gaataacagt
    39301 tcttgataga tttcttgttg atttttttgt tcattttgct gatctaaccg tgttttgatt
    39361 ttcttgaggc tttcaaccaa ttcgaactta ttcacgggtt tcatcaaata attcacggcg
    39421 cctaattgca tacctccttt caaataatcg aattcttggt atcctgataa aatcataaat
    39481 tcaaaattat gacgttcttt ttgagccgct tcaataaatt ccagtccatt tatttctggc
    39541 attgtcacat ccgttactac taaatcaatc tgtcgctgtt caagtacagc tagtccttct
    39601 ttggcattct ctgctgttgc tactatttga aagcctaaac tttgccaatc aattatcttt
    39661 tttaacccat tcaaaatcat gtattcatca tctaccaata acacttgata cacgctcatc
    39721 cctccttgaa tgtaatagaa acggtcagtc cacctgtctc attattctca agcgacatat
    39781 aataactgct gccgaagctg gcacgtaaac gttcattcac gttttgcaga ccgatagaac
    39841 cgtgaagttc cactttagga tgagacagtt tttcttcaat ctgttttagc cgtttttcag
    39901 tcatcccttt tccattatct ttgatgatga tccttacccg tttgccttcc tgcaagactt
    39961 tgacacttag cgcattatcg aatcgagtaa aatcaatacc gtgtttaaaa taattttcaa
    40021 ctaatggctg gatcacaaat ttaggtactt cgatcttttc caaatcagga tcgatcataa
    40081 aatgataggc tactcgatta ggataacgca tttgatacaa atagacatat ttttcgcaaa
    40141 agtccagttc ttcttttaaa gtgatcgttt tctcttgatt cgtattgttt cgaagcaaag
    40201 cggaaaacgc atacacaaca tctgctaatt cttcacttcc ttcgctgatt gcatacattc
    40261 ggatatattc taatgtatta tataaaaagt gtggattgat ctgtgcttga agcgcccgca
    40321 tatgtgcgtc ttgctgtttg atttctaatt tgtagatgtc ttctacaaac tgattgatgc
    40381 tatccaacat ttcgttgata ccgattgaaa gttccttcag ttcatattcc gtgtttgtta
    40441 tgtcgatccg cgtctctaaa ttccctgctg ctgtttgatc catggcctgc atgacgatag
    40501 atacttgctg tgaatatcgt ttgaatgttt tataaagaaa gataagcagt atattgtcta
    40561 aaataatgat accaatgatc agcggggcaa gattttttcc cgtttcgatt tttacacttt
    40621 ttttatctag tacagctaat atacgataat catcagacag ttcttggtgt tgaacaaaat
    40681 tgtttttttc cagatcgtca atcggcaatt gtgaattttt cttcagactc tctgtgatga
    40741 tcatttcttg tctttcaaac gtttctttag ctattttatt atcatggaat gtgtatagtc
    40801 gatttgtcgt tccagaaatc atgtataaag agagtccatt gaatgacgtt agattttcta
    40861 aaatcatatc tagttctttc ttttgaaaac caataaaaat acttcctgac tcagctcctc
    40921 cttgtgtgat aggcaacttg atataaaagg cgtctagtaa ttttggtgtc ccctttttta
    40981 tttccccacc tttgttttct ctagaagatt cataatactc cggtagttga ttcaacacga
    41041 tatatatcgc acttagttct tcataatttg cgtagagatc tttgatttga tttgggaaag
    41101 aaactaattc atcggtactg ttttgctgtt cgtatacata catcagatac tgatctatgg
    41161 gttttgttaa gtaggtcgtc acattttcga tcttttcgga attccctaca agctggtttt
    41221 tgatgatcct actcaaggtt gttttatcat tcagcattct gcttgtgctt tgaacggcat
    41281 cacttgtcat gttttctgcc tgtttttgat tttgttccca agtatggata ctaaaaataa
    41341 cggtagcagt catcgttaca ccgatcatga taaccgcgta tttccgcaac agacgattta
    41401 gtaaggttcc ttttgaaaat agaatccgaa acttattcat aactttccaa ctgtttatct
    41461 aattcttcac gccaatgtgt tgtcatcgta ccattccaaa ccgtcaaaag accaatgaca
    41521 ccaaacagga tcaatccttt gaattgccaa gtcacgccta aaattatacc gctaccaata
    41581 attattttta gaaaagacga aaagctggaa aaaaccgaaa taaaacttag ctttagcaga
    41641 ttaggaacag agatcgtata ttcactatct aaaatcatac tgtattgata agtagcaaat
    41701 aggcagagca aggcaaaaag taaaataaaa tcaatagcta aaaaaatgag ccctttgatt
    41761 tgaacagata aatataaatt gtaactcaat aaagcagtac cagataaaaa taaactaaat
    41821 agcagattgc ctcttaaaaa atttctttta tatatattcc agcctctttt tattgtgatt
    41881 tctttatact cgaatccgta caaataaaat agttcattga ctgttttcca tgccgcacct
    41941 aatccaaaga tgatcccgcc ggcaaatgta tatatccaga aatacaaggt tagttttata
    42001 atgacccaga tccggataaa taactcttcc aaaaccttcc ctaacatatc ttctcctcca
    42061 aacattaagt ttatactttc tcattataca aaaaaaggtt gggcaatcag caccttgacc
    42121 tgattattag agaaacaaac ggaaaaatag ttcctcatat tttgtcgttt tgtgagcgaa
    42181 taccgagggt tagctgattg aacaccgttt accaagagtt tgtgaaatag ccgcttagtt
    42241 tcgagtagta agaaaaattt tgtgaatatg gctttccaca tttttacata tatttagctt
    42301 aataccgaga aactggcttt tgaacaccgt ttattcggaa caagaggttg tgacacgtct
    42361 tttgtcacaa cccctttgtc tttattcatt attattcttg tcggaactca tcatattgtt
    42421 tttgcatttc tttcaatacc ttatcatagc cagccttgtc caaagcgtct ttcaatttcg
    42481 gtaatgtttc atctggatca acagtccctg tattcaatcc atctaaatat tgattcatga
    42541 cattagaaat attacttaat tctgttttga cactgtcagt gttgaagctg aatcctaaaa
    42601 tcggtgaagt ttctgcatca gcaatcgatt gatcacgttt ggcaatcatg tcatccgtaa
    42661 tagactcttg tgtatataga atcttgttgt ttcctgtatt ccaagcagac atatgtgtat
    42721 ttggctgata accatctagc aatttgattt tatcatctga accatcgact ttttcccatg
    42781 cttctccctc gatcccccaa acaagcccat tcaataattc tggatcactg ttaagcagcc
    42841 ctagaagttc tactgatttt tctttatttt ttgaagtatt tgatacgaca aaatttgcca
    42901 tttgtgcttg agctgtagat tttagtggaa cagtaattgc ttttgagaca agttcttgtt
    42961 ttgctgcatt tgtcaaaatt gtatcgccat aatcatacgg tccttgtgtt tctccacgca
    43021 ttagccaagt atttccttct agtggataat ccttattgct cgttgcagcg tcacttggaa
    43081 tgagtccttg tttgtaccag ctatgcattg tacgtaacag tccgatatac gtttcattat
    43141 cgtattggtt gatgattttc gaatcatctc catccagatc aatagcaaat ggtaacgtat
    43201 tccctaaagg ataatcaaag ttcccttgga ctttgaagcc ttgtccaatg gcaaaagctg
    43261 ccgtgtttgg ttctttttca tggaattcct tcaagacttt ttctgcatca gcgtaagatt
    43321 ggattccatc aattgaaaga tcgtatttat ctagtaaagc tttgttaaaa gtaagtactt
    43381 gttgagcaaa gacatttcca ttgactggga aagcatataa ttttccattg accagatttc
    43441 ctttaatata tgcttcatct aaatcattat aagctttttc agcgtactta ggcgctaatt
    43501 cagtcaaatc agcaaaggct cctttttggg cattggaaac atagttgttc gcaaaggcga
    43561 tatcataatt ttccccggaa gaaatgatga cgttcatttt cttttcgtaa tcgccccagc
    43621 caatgtaatt gatattgact tttacaccga tctctttttc gattcgtttg tttgctactt
    43681 ccatcaattg atcgaaatta tctggtttat ctccgatttg atacatctgc aaagtgtccg
    43741 aattgctagc ttctgcctgg tctttagaac cagaacctcc gcatgctgct aatgttccca
    43801 acaacaacgc tgaaacacct gtaaaggcta gtttcttcca taacttcatt tttcttcctc
    43861 ctaattttat gatttatatt tttgtttctt tattctttta ctccgccgat tgttagacct
    43921 ttgacaaaat gcttctggaa aaatggatag ctgatcgcaa taggcaacgt cgagatgact
    43981 acgatcgcca ttctggcaga ttctcctgga actgaggcta atccgcctgt caattggctt
    44041 cctgctcctg aattttgtgt cagatattga atattacttt ggattttcat caaaagatac
    44101 tgtagtggaa ctagcttatc atcttggatg tatagtaaag cattgaacca gtcattccag
    44161 taacccaatg cggcaaataa actgattgtc gcaatacctg gaacagctaa cggtaaaacg
    44221 atctgaacaa atattcgcag ttcgctagct ccatcgatcc gtgccgattc aataatcgaa
    44281 tcagagaccg aacgtttaaa gaatgtgcgc atcacaataa tattgaaggg actgacagcc
    44341 attggcaaga tcaatgccca aatcgtatct tttaactgaa gaagatttgt cataacaaga
    44401 taattggcca ccatccctgg tgagaacaac atcgtaatca aacaaaaaac ggtaaaaaaa
    44461 cgacggaatg gaaagtttga ccgtgaaatc gcataagcat ataaagaagt agccgtgcta
    44521 ttgatcagtg tacctaaaac agtaacaagt acagtgacga aaagcgcttg gaaaatttta
    44581 tcctgcatct ggtcgaacaa gtacgtataa ccaaatatac tgaacttttc tggccaaaaa
    44641 ctgtacccgt gagtcgacaa tatggactca tcggtaaaag agatggcgat aacaaatata
    44701 aatggcaaaa tacaggaaat agcaaagagt gcaatcatta tattagagaa aaaattagcc
    44761 gtcttattga aagagcggac ttggactctc tccactttct tttttttcat ttttttcctc
    44821 cttagaataa tgcagaatcg ctatcaaaac gtcgggcgat cgtatttgtg atcatcaaca
    44881 agacaaagcc gacaactgat tggtaaagtc ctgcagcagc cgtcatacca aaatctcctg
    44941 tggatgtcag gccattgtag atatacgtat ccaaaacttg agtcacatca tataatgcac
    45001 cggaattcct aggaatgtta taaaacaggc caaaatcagc tcggaaaatg tttcctacgg
    45061 ctaaaatcgt taaaatcgtc attagtggaa taagttgtgg tatcgtcaca tgtttgatct
    45121 gctgccattt gctagctcca tcaaccatag cagcttcata ataagtcgga tcgattccca
    45181 taacagatgc aaagtaaata atgctgttat aaccaatccc tttccatgta ccaatgaaca
    45241 ccaagataaa cggccaatat ttcggttcat tataccaatt gacagcttct cctccatgtc
    45301 cagtgatcca ctgattgaat attcctttgt caggacttaa aaaagcgtaa acaaagtaac
    45361 tgataatgac ccaagataga aaataaggta gtaaggacat cgtttgataa actttaacga
    45421 gtcgtttatt tctcaactcg ctcataatga ttgcaaatac gactgagatc agcagattca
    45481 aaaggataaa tgctacatta tataaaattg tatttttagt gatgagaaat gcttgatccg
    45541 aagaaaataa aaatttgaaa ttttcccaac ccacccaagg actttccctc aagctagcca
    45601 agaacccatc tgctgaaata tgaaaatttt tgaatgctac gacattcgcc attacaggta
    45661 tgtaaaagaa aaaaatcatc caaagcatac ccggtacagc catcaggaca agtgctttat
    45721 aacgccatag attcataaaa aaatgattga acccctttcg ttttttcatc taaaaacccc
    45781 tttcgattca ttcgcaacgt aattatagcg ctttcaataa tgagaataaa taaacaaagt
    45841 atagggaaaa tgaaacaaag tataggagag gttgtgaaat cagcgttttg gcctgagtat
    45901 tagagaaaaa aacgggaaaa tagttcctca tattttgccg ttttttgagc taataccgag
    45961 ggtcagctga ttgaacaccg tttatcagag gttgtgaatt cagcgttttg gcctgagtat
    46021 tagggagatc gtgtccttac tatctaactc tgagtcacaa ggaacaatgg ggactgtaac
    46081 aaaagtcttg tcacagtccc ttattccgaa caaacggtgt tccagaagta gcttctacgg
    46141 aaataagccg aaatttcaca aaaaagccat ccgaaagtca gacggacaag tctgcttttc
    46201 agatggcgct acaactactc tgcttattct tttagctatc cattcaatta tttttctctc
    46261 acttgttcta gctcttcttt ggtcatgggt cgatattgcc ctttattcaa atctttaggc
    46321 agccaaaatt ttcccatacg gattcttttt aaatataaga cttcttttcc tactgctttg
    46381 accattcgct taacttggtg aaactttcct tcatgcaaaa tcagacggat aattgaagtt
    46441 tctgtctctt gatctacttg atcaatttgg agttttgccg gcaatgtctg ctcatcgcca
    46501 tcaataatca gtccttctgc aaataaacgg atatcttctt ctgtcattat accgctaacc
    46561 tcagctagat attctttctc cacatgtttt ttaggtgata gtaactgatg ggcaaacacc
    46621 ccgtcattcg ttaaaatcaa gaggccctct gtgtctttat ctaatcggcc gactggaaaa
    46681 agatcttccc gataatcctg gtcttccaat aaatcgatta cggtttgatc atgattatcc
    46741 tgagtagcag aaatgactcc tgcaggttta tgcaaaatgt agtaaaaatc tttttgatac
    46801 gtaatgattt ctcctaaata agtaaccgca tcttcgaatt catttacttg cgctttatcg
    46861 cttttcacca cttgtccatt gacttcgatc gttccttttt tgattaatcc tttgacttct
    46921 ttgcggctgc caagtcccat atctgctaaa aacttatcta aacgcatgcg tttcccccat
    46981 ttcaaaagag catcaatcta gctcttctga ttcacttatt ttatttttaa tttatgtcgt
    47041 aaacgcgcta ttcctggtcc tagtagtctt tctgccaagc ggattttcaa agctaaataa
    47101 ccatacacta aagcccctat acctgctact acaagaatca acaatagaga ctggaatttg
    47161 ctatcttcgt ttaaaaaagc accaaaaatc atctttgtga tccacgaagc caaaagcata
    47221 atcaaggtaa gaataaagat cagcaatgtc ctgcgccaga caaaacttgg tttaaagcgg
    47281 gctacttcat ggattctctt taagatcaag gtacaagaca cagcaaatcc gatcattgtc
    47341 gccaataaag ggccgtatac ttcaaataaa cgaatggctg ggtattgaag aaggagtttc
    47401 actagaaacc caataaccaa ataattaatt gccgccttgt tttcaaacat tccttgcagc
    47461 atgttggaaa ctagcatata tagtcctagg aagagtccta caaaacttgc ttggatcagt
    47521 acattacttc ctagagaatc cggtgtataa aataatgtat ttagcggata ggcaagtaac
    47581 ataacaccaa atgtcgccgg aaacataaaa aatgaaaaca actgtaaatt tccgcttgtc
    47641 aattttgcca gacctactcg atctttcaac gtaacagctt ctgtaatcaa cggtaaccca
    47701 gtagacgcga tcgatgttgc caatgcaata actaccatcg tcaacttatc tggattggca
    47761 ctaaaaatcg aaaaaagatc cagtaactgt gcattggaat actcggtgga tgcagacatg
    47821 atcttcataa aagtgaactg atcgactaat ttgaagatcg ttacccctga acccacaata
    47881 ataaacggaa tcgcttcttt aacggtatct aacaacaatt ccttcgttgc aatatttatt
    47941 ttgttttcgc tgtagtgaat aaacgccgat gtatacgctt gatgtttctt caaaaaatac
    48001 aaaaggacaa gaatacttgc tagcataccg ataaatgccg cgaaagttga ttgcgtgacc
    48061 gccgtcacat agtcaccatc catgactttc atgatgatga atgtagccaa tagcatataa
    48121 aaaatacgtg ccacctgttc tacaatctgc gacagcgcat aaggcatcat ttcttgattg
    48181 ccttgcaaat accctcgtat cacactcata caaggaaaaa ccaatacagc gatactcaaa
    48241 gaacgcatcg ttggaatcag ttcttctccg ccaccagaag catgagctag ccaaggagag
    48301 gcgatgtaca tgaacaaagc aaacaacagg cctaacccgc ccatcatctg taatgcacgg
    48361 ataaataatc gtcgtgaagt gccatattca ttcaatgaat tatagcgtgc agtttgtttt
    48421 gcaatcgcag caggtattcc tgctgtagag atcagtagaa acaatgcata tatattgtat
    48481 cccatattga ataatccatt ggcagcctta gcattttcgc ccatccaagc ataccaggga
    48541 atgatataga cagcgcctag caatcttgaa atgatattac tggcggtcat ccaagcagag
    48601 cctcgtgcca ttttttcttg cggtgttaat tgatctaatg ctggttttct ttgattatcc
    48661 atcggtcaga ttccaacttt ctacaaaaca ttactatcat tttaattggt aaaacagaaa
    48721 ctggcaatcg attttatata acttttataa gaacaattgt ttttttgaat tcggtttcgt
    48781 ttttttggta aagtaaagaa atatacagcc ttttatggct aacatttata ggagatatca
    48841 atgacacaag aaataaaaaa actacccgtt atatttttag gtcttttctt tatcacagtt
    48901 ggattgaatt ggttcttgct ccctcacgat atagcttccg ccggagtggg cgccatcgga
    48961 catttagttg aaacggcctt ttctatccaa cgctcagtta ctgtttggag catcaatctt
    49021 atgatgctgc ttctagccgc tgtcctatta ggaaaatcag tattttttaa gactgtagcg
    49081 ggaagtctgc tttttcctgt tgttttagag attgttccaa aagtggaaat gatctcctca
    49141 catttctttt cactgatttc aggaagtctt ttgttcagtc ttggggttta cacattgtac
    49201 acagtcgggg cctcaaatgg cggtataacg ataccgccga ttattttcca caaatttttt
    49261 cggcttccaa tgccgcaagg acttttactt accaatagtc ttatcgtctt tttgaattat
    49321 tatgtttttg gattgttgga gacactattc gttctcctat ctattacagt cagttcattg
    49381 tttatgaaaa tactcatccg cttgtcccct gtgtcaagaa aatttgaata aagctggatt
    49441 ttgtcatagc ggaaacaaac gatatattaa aaagagtgtg ctataataaa ccaagaaatt
    49501 gaataaagcg agggatcaat caatgagctt ctctttagaa gacatccgtc atttactatt
    49561 aaaagaaaat ctattaaaag aatttgtttc aacaagaggc tggcatcttg atgtaccaga
    49621 aaaagctgaa tttcttcagt taagttatga ttcaagaaaa gctgatgctt ctactttgtt
    49681 tttctgtaaa ggaatgaatt tcaaagaaga atatttggat tcagcaatcg aacagggtat
    49741 tcaatattat gtatcagaac aaccatacga aaattcagca gtaggaatca tcgtaacgga
    49801 tatccgtaaa gcaatggcgc ttcttgctat ggctttttac gactatccgc aaaataaatt
    49861 gaaagtgatc ggattcactg gaacaaaagg taaaacaact gctgcgtact ttacaaaagc
    49921 aatcttggat cacacaacaa ataaaaaaac agcattgctt tctactatga atacaacgtt
    49981 agatggcaaa acatatttca aatcccattt gacaacgcct gagtcattag atttatatcg
    50041 tatgatgtca gaagcagttg aaaatggtat gactcatcta gtgatggaag tttcttcaca
    50101 agcttacaaa acacaacgcg tatacggctt gactttagat gtcggaatct tcttgaatat
    50161 ctcgcctgac catatcagtc cgatcgaaca tccgacattt gatgactatt tctattgcaa
    50221 gcgacaattg atcttgaatt caaaaacagt tgttttaaat catgaaagtg actattttga
    50281 tttacttagg gaaacagccg atctattcca gattccaacg atcacttatg gtcgttcgga
    50341 agaaagcaat tatcaagtga tccgttcaga taaaggtact cacggtttta ctttatcttc
    50401 tcatgaagat cgcttagcta tctgcgatac tgcttatgat attttgctgg ctggaggatt
    50461 caaccaagaa aatgcagcca gtgcgatcat tgccgcagca ctaacaggtg cctccagtca
    50521 agatgcacaa gacggattaa aagaagctcg tgtaccaggc cgaatggatc aattgatcca
    50581 atccaatgga gcgcatgtct atgtggacta tgcacataat tatctaagct tgaaaacatt
    50641 gctgaaattt gccaaaaatg aacatccaga tggccgtgta attgttgtat taggcagccc
    50701 aggaaacaaa gcaatctccc gtcgacatga ttttggaaaa gtgctatcag aaacagctga
    50761 catcgccttt ttgacggcag atgacccagc atttgaagat ccgaaaaaaa tcgcggaaga
    50821 aatcaatgaa gcaattacta atccagattt gatcgttcat tatgaaatgg atcgtcctga
    50881 agcgattcga cgcgctttag cagaaagcgc tccgcaagat tcagtcgtta ttgcgggaaa
    50941 aggcgtggat ccctatcaaa aaatcaatgg tgtagatgaa ccttatgaag gggattatgc
    51001 aatcgtgaag cggttgattg aagaataatg gtatttatat actagtggtt tcccatttct
    51061 aagaaaaaaa gggactgtga ttttttgtca cagttccttt tttcttagaa atcattttaa
    51121 cttttcacta gctaattctg ctgccttttc tctttcttca tttaataatt tattatcata
    51181 gaatttgata aatgggaacc agataatgaa tgcgatgatt gcacaaatga ctgctaacac
    51241 agcagctttc caatcaccac cactaccaac aaatgctccg atcccgactg gtgaaggcca
    51301 cggcatctgt gcaagcatcg gtttgacgat ttccagccga atggcaaaat aagcgagtgt
    51361 agcagaagcc atcggagcta agaaaaacgg aaccgctaaa tagggattgt agacgattgg
    51421 catcccgaaa atgattggtt cattgatatt gaataatcct ggtacaagtg aggcttttcc
    51481 taacactttc agctgatcag atttcgcgag gaatgcaata aagatgatca atcctaaagt
    51541 cgcacctgat ccaccaacgg ttacataaga attgttgaat tctcctgcca acggataatt
    51601 tgcgccttgt gcgttagctg ccatattagc taatacgatc ggggtcaaga aagaagtgat
    51661 gatattcgct ccatggatcc ctacgatcca caatgcatgg atcaagaaat aaatcaccat
    51721 gacaccaagc catgtattcg tcaactgcgt aacaaaccca aatgggatag caatcatttt
    51781 gaagatatcc gttcctagtg caactaataa tccattgatg atcatcacca caaacgcaat
    51841 gacaaatgtt gggatcagag cagtgaaaga acgagaaact cctggcggaa caacatctgg
    51901 catttttatg acccaatttc tcttgacaca catacaatac aattcgaccg caataatcga
    51961 cataataata gctgtaaaga ttcctgaagt tcctaaacgt tcgacaaaag agcccatcct
    52021 aataccattt actacagttt ctgtctcatt gatagaagca atcaagctga ttttaccatc
    52081 agtcatgatc aattcaggga tacacataaa gaatgcaaaa acagatagta atgcccccgt
    52141 gagcggatta acatttaatt tttgttcatc tcgttcaatt gacgttaatt cataagcaaa
    52201 cacaatggca aagtaaatag ataaaatccc catcgtcatt gtattgacga tcatgtacaa
    52261 gtcactaact ttgaaaaaag ttgcattaaa aaatccttct aaaaatggga acggtaatgg
    52321 caaaatattt aaaaccaaaa acatcgagcc tacaatcgtg aaaggaatag aagccatccc
    52381 cgctgccatg acagcccgaa cgattttaag ttgcgcaatt ttccccatag gtcccatcag
    52441 gtatttctgc aaaaaatcaa acattagtta ttctcctttc ctaaatataa cgctttttca
    52501 tattgtttaa tacggatata ctgttggtct tggttgagtg aaattttctt taaacgatac
    52561 tgtataaatg cactggcaaa aataccgctt acaacaagaa tgaaaacaaa taactgtcct
    52621 ccattgttat ttgccataaa aggatacaag aatgtaaatc ctgaggtaaa caacactgga
    52681 atcactaata aattaaagac actctggaac aaaaaatacc actttgtcca tggaacgttc
    52741 gtttggtgtt ttcgataaag ctttacttgt tctcctactg caggcaaaat agctaaaatc
    52801 agaatcatcg gtaaactact tcctaaactt ttagctgata gaagcagaat catccattgc
    52861 atgttcatga aaaagaaaaa ggcagtcagg taacgtacga ttagataacg attgaaatac
    52921 atgtttttca aactaagttg ctttttttct aattcgattt tcctttttac tgtatcctgc
    52981 acaatgatcc ttcctttcta tttatttttt tgatacaaat aattcatttc ctgtgcaact
    53041 tccaataatg tcatcgtcgt catcagatga tcttgtgcat ggaccatgat aatttccatt
    53101 tctatttttg tcccgctggc atattctttc agaagttgag tttgtgactg atgcgcatga
    53161 agaatctctt catttgcttg tcgcaacttc tcttctactt cttcaaacat ctctttacgc
    53221 atcgagcgaa atgcttcatg tatcagtgtc cgtgcatttc cgctatggaa aatgatatca
    53281 aaagaagtca cttgtagtgt ttcactgttt attttttcag ccatctgttt tcctccttat
    53341 tcgatcagtt tgataaattt actgctgaaa ttctcaaaaa taggttcagc taagatttcc
    53401 tgctgtactt ttagctggtc aactaaccta acgattgctt tagtcacgac cgtaattcct
    53461 tcattttcga cataagaagg cgaaactaaa aaaacaaaat gaatttcttg atattgatcc
    53521 cactgcatcc cagaaggaat caatgcaacg gctacctttg tttcgattcc aactggaaca
    53581 gcgggatgtg ggactgccac tgtatcactg aatatgattt gtcccatatt ttcacgttgc
    53641 tggatctgct ttcgcatttc tcttatatat ccttcttctt catttatgct cagcttttgc
    53701 agcaaatcat gaagaatttc ttcctttttc ggttcgtacg tataagtctt gaaaaatttt
    53761 tcagacaact gttcggtgta aatctgcttt ttttgctgta gagaaaatgc tggtatcggt
    53821 ctatctgagg aatgataggg tatagattct ccaactacct ttcgtatttt acgaacatca
    53881 tcttcattca aaaaaatact gacatgtaaa actggaattt tgaaaaacat tgtcgaaaga
    53941 tcaatagaag aaataatcag gtcgattcct tttaaagttg tttcattgat ctcataatag
    54001 ccttttacac ttaccactgt aatattttta ccgaattcac tgactacgcg attctttaat
    54061 agttgggcac tgccgtaacc cgttgcacag ataatcaatg catgtagttt atgcgcagct
    54121 ctttcttttt ccaatgccgc catgagatgc aaagccaaat aggcccattc atcttcattg
    54181 atggtatagt ttttcaaagc cggcatgttg ctgaaatgcc tttttactgc gtcaaagact
    54241 ttgggatttt ctttctttat ctcctcagtc aatgggttct caatgcgaat acctcggctc
    54301 aatcgaatca tcatcggtga caaatgatcg agtagtccat tgaaaagctg gagatcctct
    54361 actaatgaaa aatgaaattc ctgagacaat cttttcagaa ctttcgctaa ttcctttgat
    54421 agttcctgat cattttgatt ttctttgtga ttcgacttag ccatgagatg taatgtcaaa
    54481 taagcaattt cttcttcggg aaacgataca cctgcgatta cctcaatacg ttgaacgatc
    54541 cgctgcgcca cttgatactc tactcgctta gaaacttctt gttcgatgcc taattccttg
    54601 atttcaaacc cttctcggag ccgtttgatc cccaaagcca agtgtaaagt cagattctgt
    54661 atgataaaat ccgaaacttt taacttagct tctcttgttt catcgagaat gataatgact
    54721 agctcttcaa aactgatgtc tgggaaaaaa cggctttgcc ctaaatattc tttcaatgaa
    54781 tttccataat ggtttccaaa aaaagtatcc atgataaaat gccgtcgatt tctttcttcc
    54841 ccttcgatcc atgtcccttg accatgctta gaaacgattt ttagtgaata tggaatcaat
    54901 cgctccttga tttcttgcat gtcctttgtc aaactggaac gactgatata aagctcttct
    54961 gccaaatcat ccataaaaag aatggcatct tccaaaagca attggttcaa tatatacttt
    55021 tgtcgatctt cggactcata aaatccttgc ggttctctag catatccagg tactatttct
    55081 tgccgactca aaaacaagtc aaatgtcagt ctttgtaaaa tatgcagttg gtagccataa
    55141 cctggtttag caatgatctt acctccgttt ttttctacta actctttgat ccgctgcaag
    55201 taattacgga ttgtccgatc agataataac aattcagaag ctaaacgttg actggtgaca
    55261 tactccttct tgtgatcaat caaatatctc aacagcaatt tttccttctg tttcattatc
    55321 atccactcct attccatcat atgttctctt cgatcacctc tgctaacttc tggatgcctg
    55381 tagggattgg gacatacgct tggaaaggga tactaacaac aggctttcca acagattctc
    55441 ctaatttttt gaatttatcc aaaaacatcg tcgtttgcgg gctgatcaga aataaatcaa
    55501 aatcactatt cttaatcata ttatcgcctt ctgtagctga aactgcatct acgagtacct
    55561 cttctctttt ttgcttaaag aaatccgttg tctttgaggc catcatcgag gatgacattc
    55621 ctgccgcaca aataatcaat gcttttttca taaatcaatc actcctttta tttttataaa
    55681 ccaagcatat cttgtaagcg ttttctattc aaaatatata tttccgtagc attgcggaaa
    55741 aaatgtgtat catatcttga ataataattt ctggcaccgt gatatactag tgatagaatt
    55801 ttttcaggag gggatttagt gagtatcaca gtgaatattt tgtatacaag tacaaatgga
    55861 caagccagaa aatttgcaga agaaatggtc gaaagaaaca ttgtcaaagc gattcgtgca
    55921 gaagaaggaa acgagaaata tgactattac tttccactag aagatccaga atctctttta
    55981 ctgatcgacc gttggaaaga tgaagaagca atcgaaaagc atcacaaatc cgaaatgatg
    56041 gctcaaataa acgaactccg taaaaagtat aaattaaaaa tgaaagtcga acgtttcact
    56101 gatttaccgt aaaaagatac acatggaatg atagcaattt atcatccatg tgtatcttca
    56161 ctttttcctt attttttatt cgatctcatc taatgattca aaccgtgttt ttctcttatt
    56221 tttcggataa gtatttcagt caccccaata tacatgattc ctaaacatac cccaaggata
    56281 ttctcaaaaa tgcggatcgt tactgctcct ggaaccccga ataaactggc agtgattgcc
    56341 aaagcaccaa aagaattaaa aactgtttta tatctatagg tagaacaaac acctaaagct
    56401 agaccaccta atataccgac ccagttaaaa ggaataaatt ggctgatacc aataaataaa
    56461 acacatccaa tcaatgagcc aatgattcgg tctactgctc gttctttgaa accaatcgac
    56521 atcaatccat agctagatac aatagaagaa aatgcaaacc ctgcccacat caatcgctga
    56581 aaagggacat actctcctgc aacgatcaaa agactaatgc caaatgcata gatgagcatc
    56641 caaatttttt cctgcgaata catgcctttc aaaaaaatct ctttaaacaa gcttttgtct
    56701 ttgttctttt ctcgatgttt tctgtaaagg agaactgaaa accaacaaaa aaacaaaaat
    56761 aataagctac ttgtttgtgt aaagaaattc ttgttcaacg aatctttagg taacgaataa
    56821 acaataaaga gatatgaaaa gccgtacaaa gaagcattcc ccattttggg atcactagcg
    56881 gttgccatta atatgctgct tagtaaaata aaatgaatca acatgcccat aactgaccat
    56941 ttgatcagct ggacatacgg tgctactaat agtgagaaca tgacgattgc taaacctatg
    57001 atcgaatggg aaatcttata accaaagtca acaaaacgaa tactcatcaa catacagaat
    57061 aaaaccacag cgtatggttt atgcttcgat tcaaataatg ttgtaattat aatgataaaa
    57121 caaatggcaa acaatacgat gaataatgat cgtaaaaaca atgaacaaat atacatgcac
    57181 ttttcttttt tagaagctgc ttctcgtatt ttttgtttta aaataaacgg atctagttgt
    57241 agagactgat aaaaatccac ctgttgtcgt cctttctttt tacttttatt ttttacagtc
    57301 atctatgaca ggttgtaaat actatggaac atcatatggc gttgtcattt tcttgtcaac
    57361 tatttttcct attcatgttt ttataaaaaa acatatcgtt ttcttgtatg attaaatcac
    57421 cacaaaataa acaactgaga gaacgatatg ctttatgaat ggttctatca aaaaaattct
    57481 gagatcaata gacaaaaatt tgatgattac agaggtctct tacgaaacct tacagaagaa
    57541 aaaaacattg atcgttgctg cagttctctt ccctgctcca tgtgtctgta gaaattgtgg
    57601 ttctgctgtg gtagatggaa ataggaaatt aatggtggtg aaaaacaaga agaaggaaac
    57661 cattgtccac tttgaataat ataatcatat gccaatggtt atacgcctaa aaaagcagcg
    57721 ctatacctgt aaaaactgtc gaagccattg gaacgctcaa agttatttta tccgtccaag
    57781 gcactcgatt tcaaatcatg tcagacataa aatcacttct ttactgactg aaaaagtgtc
    57841 gttatttttt atttcgaaaa gttgttaggt atctttgaca accgttattc gcacattgaa
    57901 agagttgaga agctatttac caaagtcttc caaaagaatt ctgtcttgag tgttgagggt
    57961 tgtgaatttc gttctcacgt ttccgttgag gataaactga gttttatttc cgcggatggc
    58021 gagacagaaa aattaatcga gaaaatttac ctacacaaaa aattcctcga ttaacaaact
    58081 atttccttag ctgcactaat cctaaagaaa tagaattctt agttacagac atgaacgcca
    58141 cctactttca gctcaccaaa catgttctac caaatgcgaa attggtgatt gatcgattac
    58201 ttggtttttc cacgcctttc aaggaggcgt aacctttatt cacgagttgg ttgaagcttt
    58261 ccgagacaaa agacccgact tgtttttctc cttattgaca aagagccatt aaaactagag
    58321 aaaaaattac aactgatcgc tgattatttg tagaaagaaa atcaaagtat tacccaataa
    58381 acttgagtca ttaggcaaaa agcactgcga aactcaagaa tgattttcgc agtgtttttg
    58441 tatatttttt attaactagt attactacaa aggtttattt ttcacttctc aacgcagcac
    58501 aaaattgtct ttacttattt actggttggg ttcaaccttc tctactccga tactaatatt
    58561 tgtttgtata ccccttctaa aatcggtagt ttccattcaa ttgatgggta ctagttgatt
    58621 ttaaaaacta tgcttattca attttttatt ttagctcata tatttcgttt ctttctaaat
    58681 tttatactga tgaaaacaag tagcacaccc aatattgaca atataaactg gctaatgatg
    58741 gtttctccag tttttggaag atgcttattt ccactgcttg ttggattgtt tcctcttata
    58801 tctgagctat cagcaacttt tctattctct tttgttaaaa agatcgccac ttcttgttct
    58861 ttttcgatct tgaaagttac tggtgtcgca tccaattcat accccgttgg cgcttgagtt
    58921 tctaccagct gatatgctcc tggtgctaag ccatctatcg ccagttttcc atctgctcct
    58981 gtggttagac ctgactgcag aacggttcca ttggcatctt gtaactcaaa aacagctcct
    59041 tgcaggactt ctccgctttg gtcatcgatc tttgtcaaca cgacaccgcc tggtgtaagt
    59101 cgattttctt tcgtcaattc taccaccgct gtctgacttc tttcgatctc aaactcgatt
    59161 ggtgtcgcat ccaattcata ccccgttggc gcttgggttt ctaccagctg atacactcct
    59221 ggtgctaagc cgtcaatcgc cagttttcca tctgctcctg tggttagacc tgactgcaga
    59281 acggttccat tggcatcttg taactcaaaa acagctcctt gcaggacttc cccgctttgg
    59341 tcatcgatct ttgtcaacac gacaccgcct ggtgtaagtc ggtttgcttt cgtcaattct
    59401 accaccgctg tctgacttct ttcgatctca aactcgatcg gtgtcgcatc taattcatac
    59461 cccgttggcg cttgagtttc taccagctga tatg
//
LOCUS       DAIGQM010000009        57914 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.009, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000009 DAIGQM010000000
VERSION     DAIGQM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.009"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            271..837
                     /gene="amaP"
                     /locus_tag="NOA48_000494"
     CDS             271..837
                     /gene="amaP"
                     /locus_tag="NOA48_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0788788.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            850..1038
                     /locus_tag="NOA48_000495"
     CDS             850..1038
                     /locus_tag="NOA48_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0788789.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1051..1608
                     /locus_tag="NOA48_000496"
     CDS             1051..1608
                     /locus_tag="NOA48_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0788790.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1640..1882
                     /locus_tag="NOA48_000497"
     CDS             1640..1882
                     /locus_tag="NOA48_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0788791.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2223..3437
                     /locus_tag="NOA48_000498"
     CDS             2223..3437
                     /locus_tag="NOA48_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCI0788792.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3468..4895
                     /locus_tag="NOA48_000499"
     CDS             3468..4895
                     /locus_tag="NOA48_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0788793.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4918..5844
                     /gene="glsA"
                     /locus_tag="NOA48_000500"
     CDS             4918..5844
                     /gene="glsA"
                     /locus_tag="NOA48_000500"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCI0788794.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6052..7512
                     /locus_tag="NOA48_000501"
     CDS             6052..7512
                     /locus_tag="NOA48_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788795.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIVLSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7733..9496
                     /locus_tag="NOA48_000502"
     CDS             7733..9496
                     /locus_tag="NOA48_000502"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCI0788796.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9580..10038
                     /locus_tag="NOA48_000503"
     CDS             9580..10038
                     /locus_tag="NOA48_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCI0788797.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10147..10830
                     /locus_tag="NOA48_000504"
     CDS             10147..10830
                     /locus_tag="NOA48_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI0788798.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10977..11591
                     /locus_tag="NOA48_000505"
     CDS             10977..11591
                     /locus_tag="NOA48_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCI0788799.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11607..11813
                     /locus_tag="NOA48_000506"
     CDS             11607..11813
                     /locus_tag="NOA48_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788800.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTINGLFNYFNK"
     gene            12352..12909
                     /locus_tag="NOA48_000507"
                     /pseudo
     CDS             12352..12909
                     /locus_tag="NOA48_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            12967..15006
                     /locus_tag="NOA48_000508"
     CDS             12967..15006
                     /locus_tag="NOA48_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCI0788801.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15115..16266)
                     /locus_tag="NOA48_000509"
     CDS             complement(15115..16266)
                     /locus_tag="NOA48_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCI0788802.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(16420..16950)
                     /locus_tag="NOA48_000510"
     CDS             complement(16420..16950)
                     /locus_tag="NOA48_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0788803.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(17049..17399)
                     /locus_tag="NOA48_000511"
     CDS             complement(17049..17399)
                     /locus_tag="NOA48_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCI0788804.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17556..19085)
                     /gene="ahpF"
                     /locus_tag="NOA48_000512"
     CDS             complement(17556..19085)
                     /gene="ahpF"
                     /locus_tag="NOA48_000512"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCI0788805.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(19095..19658)
                     /gene="ahpC"
                     /locus_tag="NOA48_000513"
     CDS             complement(19095..19658)
                     /gene="ahpC"
                     /locus_tag="NOA48_000513"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCI0788806.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19802..20464)
                     /locus_tag="NOA48_000514"
     CDS             complement(19802..20464)
                     /locus_tag="NOA48_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0788807.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20648..22294
                     /locus_tag="NOA48_000515"
     CDS             20648..22294
                     /locus_tag="NOA48_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCI0788808.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            22285..23367
                     /gene="uxuA"
                     /locus_tag="NOA48_000516"
     CDS             22285..23367
                     /gene="uxuA"
                     /locus_tag="NOA48_000516"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0788809.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDIGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(23475..25028)
                     /locus_tag="NOA48_000517"
                     /pseudo
     CDS             complement(23475..25028)
                     /locus_tag="NOA48_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25176..26317
                     /locus_tag="NOA48_000518"
                     /pseudo
     CDS             25176..26317
                     /locus_tag="NOA48_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(26443..27522)
                     /locus_tag="NOA48_000519"
     CDS             complement(26443..27522)
                     /locus_tag="NOA48_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0788810.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27625..28065)
                     /locus_tag="NOA48_000520"
     CDS             complement(27625..28065)
                     /locus_tag="NOA48_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0788811.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(28122..28532)
                     /locus_tag="NOA48_000521"
     CDS             complement(28122..28532)
                     /locus_tag="NOA48_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0788812.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28712..29146)
                     /locus_tag="NOA48_000522"
     CDS             complement(28712..29146)
                     /locus_tag="NOA48_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0788813.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(29246..30094)
                     /locus_tag="NOA48_000523"
     CDS             complement(29246..30094)
                     /locus_tag="NOA48_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0788814.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            30483..32249
                     /locus_tag="NOA48_000524"
     CDS             30483..32249
                     /locus_tag="NOA48_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCI0788815.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            32351..33610
                     /locus_tag="NOA48_000525"
     CDS             32351..33610
                     /locus_tag="NOA48_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0788816.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33757..35058
                     /locus_tag="NOA48_000526"
     CDS             33757..35058
                     /locus_tag="NOA48_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788817.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            35061..35912
                     /locus_tag="NOA48_000527"
     CDS             35061..35912
                     /locus_tag="NOA48_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788818.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            35925..36740
                     /locus_tag="NOA48_000528"
     CDS             35925..36740
                     /locus_tag="NOA48_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCI0788819.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            36891..38057
                     /locus_tag="NOA48_000529"
     CDS             36891..38057
                     /locus_tag="NOA48_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0788820.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            38287..38934
                     /locus_tag="NOA48_000530"
     CDS             38287..38934
                     /locus_tag="NOA48_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0788821.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            39018..39962
                     /locus_tag="NOA48_000531"
     CDS             39018..39962
                     /locus_tag="NOA48_000531"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCI0788822.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            40097..41548
                     /locus_tag="NOA48_000532"
     CDS             40097..41548
                     /locus_tag="NOA48_000532"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCI0788823.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41569..42405
                     /locus_tag="NOA48_000533"
     CDS             41569..42405
                     /locus_tag="NOA48_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0788824.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            42405..43064
                     /locus_tag="NOA48_000534"
     CDS             42405..43064
                     /locus_tag="NOA48_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0788825.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            43190..43879
                     /locus_tag="NOA48_000535"
     CDS             43190..43879
                     /locus_tag="NOA48_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788826.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            43885..44841
                     /locus_tag="NOA48_000536"
     CDS             43885..44841
                     /locus_tag="NOA48_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCI0788827.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            44885..45397
                     /locus_tag="NOA48_000537"
     CDS             44885..45397
                     /locus_tag="NOA48_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0788828.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45653..46201)
                     /locus_tag="NOA48_000538"
     CDS             complement(45653..46201)
                     /locus_tag="NOA48_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0788829.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(46290..47471)
                     /locus_tag="NOA48_000539"
     CDS             complement(46290..47471)
                     /locus_tag="NOA48_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCI0788830.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47707..49215)
                     /locus_tag="NOA48_000540"
     CDS             complement(47707..49215)
                     /locus_tag="NOA48_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCI0788831.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            49374..49565
                     /locus_tag="NOA48_000541"
     CDS             49374..49565
                     /locus_tag="NOA48_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788832.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49768..50685
                     /locus_tag="NOA48_000542"
     CDS             49768..50685
                     /locus_tag="NOA48_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCI0788833.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50678..51751
                     /locus_tag="NOA48_000543"
     CDS             50678..51751
                     /locus_tag="NOA48_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788834.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            51899..52417
                     /locus_tag="NOA48_000544"
     CDS             51899..52417
                     /locus_tag="NOA48_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788835.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            52398..52790
                     /locus_tag="NOA48_000545"
     CDS             52398..52790
                     /locus_tag="NOA48_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCI0788836.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            52866..53801
                     /locus_tag="NOA48_000546"
     CDS             52866..53801
                     /locus_tag="NOA48_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCI0788837.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            53934..54713
                     /locus_tag="NOA48_000547"
     CDS             53934..54713
                     /locus_tag="NOA48_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0788838.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54706..55023
                     /locus_tag="NOA48_000548"
     CDS             54706..55023
                     /locus_tag="NOA48_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0788839.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            55267..56877
                     /locus_tag="NOA48_000549"
     CDS             55267..56877
                     /locus_tag="NOA48_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0788840.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            57034..57882
                     /locus_tag="NOA48_000550"
     CDS             57034..57882
                     /locus_tag="NOA48_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0788841.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        19267 a        10228 c        11304 g        17115 t
ORIGIN      
        1 taaatagaat cttgtaataa taactgagca taatctttgc aatttttaat cttgaataat
       61 atcctttaag tatagccagc aatcaaaagt aaatagagaa taagtaagca attgttattt
      121 cagtatcaga ctggcaataa aacgccgtta tgatccagca atgtttggta gcgctttatt
      181 tactgatgct atgctaactg ttcgctatct atactgtgat tgtcggtaga gttatttaca
      241 gggtaaaaat aagtttatag gaggtggaaa atgaataagg ggttaaaaat aatcggtgtt
      301 atcatgagtt tactgctact ttcagtattt ctagcgattg cgttgatcaa tgcgccgtat
      361 attatgcctg aacaattgga acgatttcgc ttctttactt taacgaatta ctacatgcaa
      421 caatatattt tctgggcagc tgtagtattt gccgttcttg ctattatcat cttgctagtc
      481 gttcttttct atccaaagtc aagaggaact ttcgttatga aacgggaaga tggcaaacta
      541 acaatcgaca aaaaagcgat cgaagggttg gtacgttccc atttacacga agaagagttc
      601 attcattcac ctaaagtacg gatacgttca acgaaaaatc gaatccatat ccatgtcaac
      661 ggagacttga aacgaacttc ttcattagta gggaaaacag gtgtattgat gcaagatatc
      721 gaagaagaag taactaaagt actcggaaca aaagaaacgg tcaaagtggc agtcacatac
      781 agcggttatg aagaacaaga agatacaaga gactacaagc actctcgagt ggaataggag
      841 ggccaaataa tgaaagaact attttcagca tacaagctcc ctattatctt tgggggtctt
      901 ggactactgc tagctgtttt atggttaacg attggatttt tcaagacatt gttgatcata
      961 atcatgacag caattggcgc aggaatcggt ttttatttga aacagtcagg aatagttgat
     1021 caatttttta aatcatagga ggaaacaaag atggaaaaca aaaacatgaa tacaacaaat
     1081 ggatcagttt tggcaaatga aaaaggagaa aaccgcatga tgaatggtga attgacttat
     1141 gaagacaaag tcatccaaaa aatcatcggt tatgcattga aagatgtaga tggtctattg
     1201 acattagatg gcggattttt ctcaaatatg gctgaaaaat tagtcaacac agataacgta
     1261 acagcaggta tcaatacaga agtaggtaag aaacaagtag ctgtggatct agatgtgatc
     1321 gtagaatacg gtaaagacat cgaagatatt tacaaccaaa tcaaagaatt gatcagtact
     1381 gaagtaaaca atatgacaca tttagatgtt atcgaagtga atgtgaatgt tgcagacatc
     1441 aaaacacaag aagaatacca aaaagatcaa gaaacagtac aagacaaagt aacagaagca
     1501 gcaaaatcca caggacaatt tgcttcacgc caaacagata aagcaaaatc tgctgtaggc
     1561 aaaggtgcac aaaaagtcaa agaaaataac gaaccacgtg tacaataaga agtaagaagt
     1621 cagttaggag gaatttaaaa tgggatttat ttgggcatta atcgtcggcg gtatcattgg
     1681 agcaattgca ggagcaatca cgaataaagg atcatcaatg gggatcatcg caaacatcat
     1741 tgctggttta gtaggttcag caattggaca agctttacta ggaacttggg gaccaacaat
     1801 tgcaggaatg gctatcattc catcattgat cggtgcaatc attttagtat tagtcgtttc
     1861 attctttgca cgtaaattat aagcaaattg aagaaaaact tatgttgaaa tgaagaacaa
     1921 atttgagaac cgtagcgaca ctcgctgcgg ttctttttta tatattttat atgaagtatt
     1981 ctttattcct tatgaaaaaa tatctttaaa aataaaaaaa gacgaaaata aacggttttc
     2041 tataaaaaga agaccgttta ttttttgtct ttatttgtgt gaaaaacgaa aaagagcaca
     2101 acacatcaag cttttattaa ttgtctgtct tttataaatg caagtattaa ttcaaaaaaa
     2161 cagaagaaaa aaacaactac accttctttt atactcgtaa tcgtagaaag gaggcgaaaa
     2221 aaatgaatac attacctatc aatacaggag atacagcatt catgatttta tgtacagcaa
     2281 tggtttgcct gatgactcct ggtctagctt ttttttacgg cggattagca cggaagaata
     2341 atatactaac gatcatgtct caatcttttc tctccgttgg gataacaacg attatgtggg
     2401 tatttggtgg attcggattg gcctttggac gggatatcgg cggtgttatt ggaaacccgg
     2461 cagatttctt tttgatgaga catgttacaa gcttccccaa catgtttcat ggtgcaacga
     2521 ttccattttt aatgttcttt ctttaccaac tgatgtttat cgtgattacc gttcctttga
     2581 tgacaggagc ttttgcaggg agattgaatt taaaaggcta tattatactt gttatttttt
     2641 ggaatctgct gatttatttc cctgtttgcc actggatatg gggtggcgga tttttggatc
     2701 agatgggatt tagagatttc gctggtggag cagtcatcca cacgacagct ggattcggct
     2761 ctttagcatg tatcctcaca cttggtcaaa gaaagattcc tttaggagaa agaagtcagc
     2821 atagcagtct tatggcagct gctatcggta caggactgct ttggtttggc tggttcggtt
     2881 ttaattccgg tggtgcactt cgagcagatg aacaagcagt caatgcattt ggttcaacat
     2941 tcatcgctct tgcatttgcg atgattactt ggctgatcat tgcaaaagta aaaggaaatg
     3001 gctttgattt tgtcgacgta ctaacaggat ccgttgctgg attggcagcc attacgcctt
     3061 gtgccggtta tgtagaagca aaaagtgcca tgctgattgg gatcattgcg ggtatcgtct
     3121 gtcatgctgc tgttgatttt cgtaaaaaga aacaatggga tgatgcactt gatgtgtggg
     3181 gtgttcatgg catgggcgga ttcacaggta cgattctgat agggatcttt gcatctaaca
     3241 gccatttact aacgaatcca agcagctggt acttcttagg gattcaagtg attggtgtca
     3301 tcattactgc cgtgtatgcc tatgtgctga caacagtgat tttaaaatcg gcgatgcact
     3361 ttacaacgat cactactaca aaagaagaac aagaagaagg attggacttt ttcttctttg
     3421 gcaacaaact caattgaaac aaattcaaat agaaaagagg aagattcatg caacaaagca
     3481 aaacgaaaat tcctgcaaaa aaattaacgt tctttggctt tttggctatg accatctcaa
     3541 tggtcgtttc attatatgaa tatcccacat tcgcgacctc aggcttcagc ttagtatttt
     3601 tcttgttatt aggcggtttg ctatggttta tccctgtggc attgtgcgca gcagagatgg
     3661 caacggtgaa aggatgggaa aaaggcggtg tctatacttg ggtcagtcgc acattgggaa
     3721 aacgattcgg ttttgccgca atctttttcc aatggtttga gataacagtt ggctacttga
     3781 ccatgctgta tttcttaact ggtgcattat cctatgcaac gggtattggt gctatacaaa
     3841 acaataaata tctgaaattg gcaatcctat tgattatttt ctgggctatt ttactctcac
     3901 agttaaaagg aaccaaatac acttcattga ttgctcggat cggttttgta gctggtatct
     3961 tgttgccagc attagtcttg tttggcttag ggatccatta tgtcgcttca ggcgctccac
     4021 tacaaacgat actgtctatg aaaacattga ttcctgattt ttcgaaattg cctacgctgg
     4081 ttgtttttgt ttcctttatt ttagcatata tgggcgtaga aacatctgcc agtcatgcaa
     4141 atgaaatgga aaaccctaaa aaggattatc cattagcaat gtttgtattg gttattctgg
     4201 caatcatttt agatactttt ggcggattga ccgtcgctac tacagtacct caacatggtt
     4261 tgtctcttaa tacaggggtg attcaatcgt tagaattcct attaagacac attgatccaa
     4321 atcttgcatg gattgcgaaa attcttgcga ttcttgtttg tttaggtgtc atcggagaaa
     4381 ttgcttcttg ggtaacctct ccttcaaaag cacttcacgt agcagcagaa gaaggattac
     4441 ttcctgaata ttttgcaaaa gaaaacacac acggtgttcc tgctcatttg atgatcgcaa
     4501 atgggatcgt tgcaacaatc tgggcagccg tctttacatt aagcggcggg gggaataatc
     4561 tttcatttct tgcagcgatg tcattgactg ttgtaatcta cctgatgttg tactttatgt
     4621 ttttcgcggg ctatttgaag ctggttttta aagatgacag tcttgaaaga gcctatcagg
     4681 ttccaggcgg aaaagttgta aaagtaatcg ttgcttgttt aggtcttttg acttcacttt
     4741 ttgctttttg tatctcattt gttccacctg ctagtatcgc agctggacag catgggattt
     4801 atgaaacgat tctgattgtt tcttatctta tcgtcttagt tattccattt acgatctacg
     4861 catgccgtca taaattccag catgcagaaa aataaaaaat gaaagctggt tattcaaatg
     4921 gaagtaaaag aattagaaca attgattgga aaaaatttcc actattatca aacaggacaa
     4981 gtggcggatt acattccagc attagctgaa gtggatccca aacaattagg tatggcgatt
     5041 tatgatttgg atacaaaaca actgattgag ggaggagacg ccgatgtgcg ctttgccatc
     5101 gaaagcatgt caaaagttcc cgtattgtta ttagcaatca aagacaacgg aatagaaaaa
     5161 gtctttcaaa caatcaacac ggaaccaacc ggttttgcct tcaattctat catgaatatg
     5221 gaaatcaatc atcgcaaaca tccaatgaat ccttttgtta atgcaggagc gattgcaaca
     5281 acctcgttga ttgccggtaa agatgcagat gaaaaatttg agcgaatctt gtcatttatg
     5341 aaagagatct gtgatgatcc taatatcaca ttgaatgaag aaatctatca ttctgaatca
     5401 agaacaggtg atatcaatcg ctctcttgct tactatatga aaggtaatca aatgatcgaa
     5461 ggagacgtac cggagatact cgatgcttat ttcagacaat gctccctcaa tgtcaccgct
     5521 acaggcatag caaaattagc tgctgtgctg gcaaataaag gaattgctcc ttggaatggc
     5581 aaacaaatca ttactgaaga aagtgctaca atcgtcaaat caattatgac aactgctggt
     5641 ttgtatgatg aatcaggaga gttttccgtc catgttggtg tacctgcaaa aagcggtgta
     5701 ggcggcgggt tgatggcagc tgtgccaaat cgttacggca taggtgtctt cagcccggca
     5761 ctagatccat ttggtaacag cgcagctggt atccaattgt tgaaagatgt agtcaaagaa
     5821 ctagacgctg acatctttga ataaccattc ttgaaagagg ctggggtaaa agtccaaacg
     5881 gctcaaagct acctacaatg aggctgaaat tgtgagcttg tttgactttt gtcccagttt
     5941 ctttttttat tggtttttga aagggctttt ctaaataaaa aggaaacaaa aatacgattt
     6001 acagatatga ttaaataaaa tcataagaaa aactggaggc gtgtatcagg aatgctggaa
     6061 aattacatcg agcgaaatat atttagaaaa gtgtatctgt gtgaacaatt atttgaattc
     6121 caagaaatag acatcgaaca aacagctatt tctctaaggg tgactacacc aacgatcctt
     6181 cacgatctag aaagtctagc cgagtgtcta gaatattgta taaaagaaca agtaagagag
     6241 aagcataagt ataaactcgt attcaaacat ggtattgttc tttctgagct cacacagttt
     6301 ctgtacggtc aatcttattt tttaaagttt ttaagttatt attttaatgg tatattcacg
     6361 agtacagaac tggctgatct tgaatttatt tctttgagca aagtatatac aatcaaaaaa
     6421 atcgtattgg atttttttaa agaaaatgat tatttgaaaa ataaagaaat cattatccca
     6481 gaatttgact cgcggaacat cttgctagct ttagtacgtt atgtcaattg ggaaggctat
     6541 gaaaataaaa atccgtatgt agaagaagct tgtaacgagt tgattgatta tgtagagact
     6601 cattttttta aaagaagata ttcggaagat gaaaagtcct ttatcatacg aggaatagag
     6661 atcgcaatcg gaagaaaggc atttcccctt ggactgaaag aagaagataa gaaaagcgca
     6721 gaaacgaagc cgttatttca attagtctgt caaggattgg aagagcaaaa aggaattcta
     6781 gacttacaag aagaagatgt ctattatatt ttttctttgt tcaacagtag aaattatacc
     6841 aatgagaaca tggagctgtt aagaaaagat ttcgaagttg tttataaaaa ttttgttctc
     6901 aatgacctat cactgaatga attgatttta cagattatta gtatcgctga aatcgacgat
     6961 gcagaaaatt ttattttcaa gcaatccttt ttacaatttg tccgtacgtt gtgggcagat
     7021 ggacaagtat ttttaccgga aaggatctat cttctatcag aaaaagaaca acttctgtac
     7081 ggaaaaattg tagaaatatt ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg
     7141 aatgaaaatt tcattcgaaa attcgtcaaa agtctttctt tgatcaacag tgaacaagcg
     7201 gggagacagg aaatagaaat ttttgttgtt tcagaaagtt cagtcaaaca atttttttat
     7261 cgaacccaat ttcatttgta tgcggaagaa ggcatcgctg aaataaatcc tattttattt
     7321 cgttcattag aagaattgcc tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc
     7381 gatgctgcta gctatcaaaa tggattagaa actgaaaaga caaagatcta tccaatctca
     7441 ttaaaaggtg caaacatcca tttgtatcat attgctcagg aacttcacct attaaaaaaa
     7501 catatttctt gatgagacct taattaggag accttctaca aagcttttta attgtctgta
     7561 gaaggttttt atttgagtcc tgattcgtgc gaagatctac ttatataaca agctttctct
     7621 gaaatttttt taaaatgcta ttgacttaga gtcaactcta agtagtagaa tagataaagt
     7681 gtaacaaatc tattttcatt aaaagaagat agtacggagg agagaatgta ttatgagtac
     7741 agtattacat gtattggatg caatcaatag ccccgcagat gtcaaaaaat tatctgttga
     7801 ggaaatgaaa cagttggcag aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt
     7861 aggtgggcac gttggtccga atctaggtgt agtagaatta acgattgcgt ttcattatgt
     7921 atttgattca ccaaaggata aaatcgtttg ggatgtttcc catcagtctt atggtcataa
     7981 gcttttaact ggtcgaaaaa atggttttga aaaaggacat taccgtgaag tgagcggata
     8041 ttccaaccaa catgaaagta aacatgacta ttttacagtg gggcacacat ctacatctat
     8101 cagcttagca acaggtttag ctaaagcgag agatctgaag aaagaatcag gaaatgtggt
     8161 agcatttatc ggtgacggct ccctaagtgg tggcttagct tttgaaggat tgaacaatgg
     8221 tggtgtttta caatccaatc taatcgtatt agtaaacgat aatgagatgt ctattgatga
     8281 gaatcatggc agtttatata aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag
     8341 caataaccta tttaaagcaa tgggatttga ttatcgttac gtggataatg gaaacgatct
     8401 ggaaacggtg atccgtttat ttgaagaagt aaaagatatt gatcatccga ttgtacttca
     8461 cgtccatacg gaaaaaggtc gcggttatca gccggcaatc gataataaaa tgaaatatca
     8521 ttggcatgta ccatttgatc tgtccaccgg ggaggcaaag caagtaactt ctggagaaac
     8581 atttaatatg atcatcatgg attatttgga taagaaaatg caaacaagta cagctcctat
     8641 tgccgcagtc aatgcagcga taccaggcgc ctttggactg aaaacattcc aagaaaaaca
     8701 tccagatcat tattttgacg tggggatcgc tgaacagcac tctatcactt tcgcttctgc
     8761 tttggcttct cagggagtac gtccagtcgt cttccaatca agtactttct tgcaacgggc
     8821 atatgatcaa ttatcacatg atttagcgat caacgagaat ccagtgatta ttttagtcgg
     8881 tggcggaacg atctcagcta gtgaccgaac acaccaagga acatttgaca ttccttactt
     8941 atcaagtatc ccgaacatca aatatcttgc tccagcaaca aaagaggata tgatctctat
     9001 gctagattgg gcgttcgaac aaacagcgca gcctgtagca atccgaattc ctacacatgg
     9061 tgtagaacat ggtacagcta tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa
     9121 taatggagga aaagtagcaa ttttagcttt aggcggtttt cttgaattag gaaaagaaac
     9181 agtaaaagct tttagaaaaa aaggaatcga agcaacgttg atcaatccag gaacgatcac
     9241 agaaaatgac gtagaaacat tagataaatt aaaagaaaca cacgaattag tcatcacatt
     9301 agaagatggt agtttgtcag gaggatttgg cgaaaatatc agtcgttatt atggtgattc
     9361 ttcaatgaac gtattaaatt ttggtgcaga gaaagaattc acggatagcg ttcctgtagg
     9421 gcagctttat gaacgttatc atttaacacc aaaacaaatc gttgaagata gtctgcgtgt
     9481 cttgaatatt caataattca ttatgctcac catccagata attgtttata ctagtatctg
     9541 gatggttttt tcattataaa aagcaaaggg gtggatgtta tgtatcagca agtagaagaa
     9601 tatgtcaaaa agttccaaga aaaatatcct agttatcaat cagaaaaatt aggtttcttt
     9661 tcatttgggg atacagaaaa aatggcagac gagttgagcg aactagttgt aaaaaagata
     9721 aagactggta catcaagtgg ttacgatctg tataaacaag agaatgagcc tttaccaaaa
     9781 gttggtcaat tagacgtggt cctgaatgga aaaaatgaac cagtttgtat catcaaaaat
     9841 ataaatgtga ccatcttgcc ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga
     9901 gaaggggatc ggacattagc ttattggcgg aaagtccatg ctgagttttt taaacatgct
     9961 tataaagaag cgttgaacat agaatttaca gaagagaagc tggtcgtata cgaagaattt
    10021 gaagtaattt tcttttagta agaaaggtct gctgaaagaa atagctcatt attgtctcct
    10081 gaatagaaaa gggttacatt tttatatgaa gctgtatttt tatataacat tactggagga
    10141 gatattgtgg atacactgga acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg
    10201 gaaaacgagc cgctacacag ttcttttatt atggggagaa tggctttggc tgcaaaagaa
    10261 ggcggagcag ttggtattcg agcaaatacg acagaagata tcaatgaaat caagcgaatc
    10321 gttgatttac cggtaatagg gattatcaaa agagattacg atgggtcaga agtgtttatt
    10381 actgcgacag aaaaagaagt ggaagaactt ttggagacgc aagcagaaat cattgcactg
    10441 gatgcaactt ctcgtaaacg tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt
    10501 cacgaacacg gtcggttagc tatggcagat atttcgactt ttgaggaagc gcttcaagcg
    10561 caagaagatg gttttgatct tttgtctacg actttagcag gctatacaga atattcacga
    10621 aagacgcaga cacctgattt tgatttattg aatcaaatca tagaacaagt cgatatccca
    10681 gtaattatgg aaggacatac tgactctcct gaacaagtag agaaagcata tgaattaggt
    10741 gctttttcag tcgtagttgg atctattatc acccgtccgc aattgatcac taaaagatat
    10801 gtcgaagccg caagtaaagc aaataactaa aaaacacgca cggcacagat tcttgacaaa
    10861 aaagaaaaat tgatagatag tttaaagcag attctaagaa gatgaaaaaa gcattacttt
    10921 tcattttgtc ttcaagatct gctttttaac gaattttata gaaagaaggc gaaaccatgt
    10981 ttgaacggag tccttcagaa ttgacagaac gtgaaaatta caagttgctg attggttcag
    11041 tcatccctag accagtagca gtagtaacga ctaaatcagc aaaagatata gtgaatatcg
    11101 cacccttcag ttacttcaat atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc
    11161 agagaaaaca agatgcagta aaagacacag caaagaatat tcttgagaca agagaagctg
    11221 ttatccatat ccttgatgag gacaacgtag aagaagtaaa taaaacagca gccaatctgc
    11281 ctaatgagga aagcgaactg tacctgactg acttgacttt aactgattca gtaatcattt
    11341 cagtaccagc attgacagaa gcaaaagttc gttttgaaac atccttatat gaacatgtcg
    11401 agatacggaa taaaaataaa gtaacagctg atttattttt gctagaagta cagaaatatc
    11461 atttaaatga aacagtctat gatgataaga caggaaggat cgatccaaga aaattgaatg
    11521 ctgtaagccg tttggcagga aatgattatg cagcaatagg agaaattttc acgattgcac
    11581 gtcccgaata aaaaggagca ctagttatgt taaaaataag ctataaacca tcgacagatt
    11641 caaaagaaat gaaaaaagaa tatgaaacag tgaatgattt tctgcaaggg cagtacttag
    11701 aagttccgcc attgcaagac cattttgtcg ttactactgt tactttagat ggtaaggaaa
    11761 tagaaatgcc agatcaaacg attaacggat tgtttaatta ctttaacaaa taaatattta
    11821 ttccgaaaag tgaaaaaaca tataaaaaaa cacataaaac taaaaaatta tcaaagaatc
    11881 ctggtgcaac tgaaagaatt tgcaacggga ttctttcaac ttatttgtta tttttttcta
    11941 aaaaatatta aagattgtta aatttcacta tttcatttca aattccattg cctaatcatt
    12001 aggaaaagtc tatcatgaac tcgtaaatag aatatagtaa taaccttgtt aggtgaggct
    12061 cctatacaaa cataggctgt tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa
    12121 actgttggat taaggctttt tccaatagct aagaatgttt tctttacgtt gtatagtgct
    12181 aaaactcgga cgatgagatg atgctaggtc agaattcttg ttcgaaaagg tttctgacct
    12241 tttctttata tttttgtgac tgacttattt gatgagacaa actcgctcct cacctgacaa
    12301 gtggattgct gtgtgaggag gagatgcggt gaaaaaagat cgattggtgg aggtcgctcg
    12361 gattcacttc tggttgcaca atacaaccag aaaacacaac aagcaaaact gatctctatc
    12421 atgagagatt catatgtcga tattccaggt tacggaatga ataagataaa tgcagcttac
    12481 tcttatgggg gagttgattt attaaatcaa acattaaagg aaaatttcaa atttgaagct
    12541 ccctattatg caagtatcac atttcaagat tttatcgatt gcgttaatga actgtttcct
    12601 ggtggagtca agatcgatgc agaaaaatct ctagatttag atggcgtata tataaacaaa
    12661 ggagagcaag tgatggatgg taatacttta ctccagtatg ctcgatttcg ggaagacaaa
    12721 gaaggagact tcgggaggat cagaaggcag cagcaagtga tcaaagctat ctctcagcag
    12781 ctgaaagacg taacttcaat attcaagcta cccaaagcgg ttgggaaatt acttggtagt
    12841 atccaaacga accttccaga aagtgtgctt ctggattgtg gtatggattt cctcaaagac
    12901 atatgttaga ataaacaggt ataaatagtg aaataaagga atgacaagca agagaaggag
    12961 gaaaaaatga aaagaagtga caagcacggc aaaaatcgaa caggcgctta tattgccggc
    13021 gcagtgatct taatagcagc tgcgggtggc ggttattttt actaccagca ctatcaagaa
    13081 acccaagcag tagaagctgg agaaaagaca gttgagcaat ttgtccaagc tttgaacaag
    13141 ggagattata acaaagctgc agaaatgaca tcaaaaaagg cggcaaataa aagtgcatta
    13201 tctgaaaaag agatcttaga taaataccag aatatatacg gtgctgctga tgtcaaagga
    13261 cttcagatat cgaatctaaa agtagataaa aaagacgatt ctacttacag tttttcatat
    13321 aaagcaaaga tgaatacctc attaggtgaa ttgaaagatc tttcttataa aggaacatta
    13381 gacagaaatg atggtcaaac cacgatcaac tggcaaccca acttggtttt tccagaaatg
    13441 gaaggaaatg acaaagtaag cctgaccaca caagaagcag caagagggaa tattatagat
    13501 cgaaatggtg aaccattagc aacaacaggc aaactaaaac aattaggagt cgttccaagt
    13561 aaacttggag atggaggcga aaaaacagcc aatatcaaag cgattgcttc ctccttcgac
    13621 ttaacagaag atgctatcaa tcaggcgatt tcacaaagct gggtacaacc cgattacttt
    13681 gtcccattga aaatcattga tggagcaacg ccagaacttc cagctggagc taccattcaa
    13741 gaagtagacg gcagatatta tcctttgggt gaagcagctg ctcagctgat tggttacgtg
    13801 ggagatatca cagcagaaga tattgataag aatccagaat taagcagtaa tggaaaaatc
    13861 ggtcgctcag gtttggagat ggcttttgat aaggatcttc gtgggacaac aggtgggaaa
    13921 ttaagcatta cagatgcaga cggtgtagag aaaaaagttc tgatcgaaca tgaagttcaa
    13981 aatggcaaag atatcaaatt gacaatcgat gcgaaggcac aaaaaatagc ttttgacagt
    14041 ctaggaggaa aagctgcatc aactgttgcg acaacgccaa aaaccggtga tcttcttgcg
    14101 cttgctagct ctccaagcta tgatccaaac aaaatgacaa acgggatctc acaagaagat
    14161 tacaaagctt atgaagaaaa tcctgaacat ccattcatca gccgatttgc gacaggttat
    14221 gctcctggat ctacgtttaa aatgattaca gcagcaatcg gtctcgacaa cggcactatc
    14281 gatccaaatg aagtgttgac gatcaacggg cttaaatggc aaaaagacag ttcttgggga
    14341 tcttttaaaa caacgcgtgt cagtagtgat gtatcacaag tagacttaaa aactgctttg
    14401 atctattccg ataatatata tgcggcacaa gaaacgttga aaatgggtga gaaaaaattt
    14461 cgtacaggct tagataaatt catttttggt gaagaccttg atttgccaat tagtatgaat
    14521 ccagcacaaa tttctaatga agatagcttt aactcagata tcttgctagc tgatactgga
    14581 tatggacagg gcgaacttct aattactcct atccagcaag cagcaatgta ttctgttttt
    14641 accaacaatg gcacacttgt ctatcctaaa ttgattgcag ataaagagac aaaagataag
    14701 aagaatgtca tcagcgaaac agcagtacaa acgatcgtgc cagatctgag agaagttgtg
    14761 caagatgtaa atggtacagc acattctctt tctgctttag ggattccgtt ggcagcgaaa
    14821 actggtacag cggaaatcaa agaaaaacag gatgtaaagg ggcaagagaa cagtttcttg
    14881 tttgctttca atcttgataa ccaaggttat atgatggtca gcatgttgga aaataaagaa
    14941 gatgatgatt cagcaaccaa acgagcatcg gaactattgc aatacctcaa ccaaaattat
    15001 caataaaaaa ttgcttttta agtacagtaa aaggactgtg gcgttatcgt cacagtcctt
    15061 ttttcaaata aacggttttc acgatgtctc tttcacaact tctttttgat ttactcacac
    15121 ttcataaact ttttttgtaa aatatttgag aacaagtgga gaaataagtg tacttaataa
    15181 aatcacgata actaaaggtg aatagtactg tggttcgatc aattgacttt gctgtccaat
    15241 ttgtaaaatg atcaaagcca tttctccacg cgaaatcata ccagcaccga ccatcaatga
    15301 actatgttga gaaaaaccgg caatctgagc accaaaataa cctccaagca atttggtcaa
    15361 aatcgctaca agcgtcaata tagaaataaa gagtagttgt tcactaaagt cagaaaaatc
    15421 aacttctaat cctacactga caaaaaatac tggtataaat actgcatatc ctaaagcctc
    15481 tacattgtgg tatacttctt ctttaacctt tgtctgactg acagctatcc cagcaaaaaa
    15541 agcaccaatg acagagctaa gcccaacaag atccgctacg taagacattc ctaaacaaat
    15601 aactagcgat acgatgataa tagaagaatt tgcgtacact ttttctgcaa atgaaagtag
    15661 gaaaggcgca atccatttga ctaataagaa aataaaaaca aaataaatta gctgttcaat
    15721 caaaacaagc ggtaaagaag cattgctaga agcttccccc gttagaaaag ataggctgaa
    15781 acttagaact aaaacgacta aaatgtcatc taccacagaa gcacccaaaa ttgttgatcc
    15841 ttcttttgta ttcactacgt ttagttcttt taatacttct actgaaatac tgacagaagt
    15901 tgccgcaaga ataatcccaa agaaaatcgc ttcatttccc gaaacttgga atgctttgcc
    15961 tgtcaaccag ccaaaaacaa ccgggaagat gatcccaagc aaagcaacga acataccagg
    16021 tcggaaatat tttttcaaaa gagataaatc actttccaga ccagctaaaa acattaataa
    16081 gatcacacca atctccgaaa agtcatggac tagaatatca ggtttgaccc aattcaatcc
    16141 agcttggcct agcaaaacac caacaagtaa ttgtccaatc actgctggga tacctaatct
    16201 ccgcgagata tgtgagccaa tcgttgttga aatcaatatc aggcataaaa taccaataaa
    16261 ttccattctc atcattcctt tgtataaaat atagcccgaa cttagcataa catacattat
    16321 tgaaaaaata ggaaaatata ctcacaaaaa aaccaacaat ccaaaagatt tttttggatt
    16381 gttggttttt atacggtcta ttttaataac taaaaatgat taacgtatag tcatttttct
    16441 tattctgatg aaattgataa tctcctggat gcccatgaaa atcaaaataa agccgaatat
    16501 ttggaataga agcatcaaac ttttgaatgg attgaacaat aagacgaatc cgccaatcaa
    16561 caacagaata ctactataaa cactccaact tttagctttt gtattcatgc tgaagaacaa
    16621 ctggaacaag ctgttgatga taacagctaa tccaagaaga atcggcagga tagaaacgat
    16681 tgcaggtgca aaagcataga cgatcagagc taagatcagg aaaaaaagac cactgaacag
    16741 accgatactc caagaacctg ttttcctttt aaaacggtaa gcctcaaaaa gattcaacaa
    16801 cccaagcaaa acaagatagg cggtgatcag ataaccgata aaatgaaaaa cagcagaagg
    16861 gtttagcaca atcgcaatcc cagaaataat ataaacagca gctcttaata aggcgtattt
    16921 ttgaatattt tgtttaatcg tctcaaacat ataagaaaac ctcctttgac ttattttaac
    16981 gtgaactagt cattttacca aattaaatgt tacaaaatga gcgaaggaga agaatatctc
    17041 tggaaaaatc aacttctgag gatcttttcc atttttttgc cttttgctag ctcatcgatc
    17101 attttatcta aataacgaat ttctttcatc aagttatcct cgatgtcttc tactcgtaca
    17161 ccacaaacaa cacctgtaat caaggaacgt gaaggattgg ggacaggggc ttccgcaaaa
    17221 aattgttcga aagtcacttg tttttgtagt tgatattcta gttctgtttg ggaataaccc
    17281 gtcagccaac aaatgatttc atctacttcc tcttttatac gatcttttct ctccgctttt
    17341 gctacataca taggataaac gcttgcaaaa cttgtcgtaa aaatacgatt ttgcgccata
    17401 atcagtcacc tttctttttt tcaaattatt tactacttat agtatataag aaaaagagaa
    17461 gaaaaagcga ttattcaaaa aaacaaaaag gattgtgaca aaattcttgt caccatcctt
    17521 ttttccgctc tctgactttt tacaatcttc atagctcaag tgcgcatcag ataatcgaat
    17581 gctcctaaag ctgcagtagc tcctgaaccc attgaaacaa tgatttgttt gtatggacta
    17641 tctgtacaat caccagctgc gaaaacgccg gggatattcg ttgcgccatt tttctcggtc
    17701 actatttcat ttcttggatt catttcgatc gttctatcta gccaatccgt attagggagt
    17761 aagccgacta gaatgaatac tcctgaaaca gctagtgtat gcatctccat cgtacggcga
    17821 tcgatatagg agagagattc tacctgattc gtaccgctga tttctttcgt cgctgcatgt
    17881 ttgataacag tgacattcgc aagagagact agtttatcct gtaagatttg atctgctttt
    17941 aattctggta agaattctag aacatataca tgttttgcta acccagccaa atcgattgct
    18001 gcttcaacac cagaattacc accaccgata acagcaatct cttttccttt aaataaaggg
    18061 ccgtcacagt gtgggcaata agcaattcct ttatttttaa actctttttc gcctggtaca
    18121 ttgatagaac gccagtgcgc acctgtcgcg atgatggcgg tttttgcttt aagtgatata
    18181 ccgttagcta agccaatatt aataaaatgt tgctctttat ttaaggaaac ggcctgttga
    18241 ttcatcataa tgtcgatagg gtaactacgc acatgacttt ctacttgctg catcaatttt
    18301 ggaccttctg tgtaagaggt accaatcata ttttcaatcc ctagtgtttc aacgacttgt
    18361 ccgccgaaag aatcagcgac aagtcctgta cggattcctt tacgtgctgc atagatagct
    18421 gcactactag ctgctggtcc accgccaatc actaatacat cataaggttc tttttcaaac
    18481 aactcttctt caatcaaagg gccagtgatt ttttcaacaa tttgttcgat cgtcatgcgt
    18541 ccgctactaa attcttctcc atttaaaaac acagttggca ctgccatgat ttttttatca
    18601 tcgatttctt tttggaacat cccaccttca atcatcgtat gagtaatatt tggatttaat
    18661 acagctaata tattcaatgc ctgtacaacg tcggggcaat tatgacaagt caagctaaca
    18721 taactgtcaa aatgcaatgt ttgtgttatt tttttgattt taagactcaa agattcactg
    18781 attttcggtg cccgtccact aatttgtaac atagccagta aaaaagagga aaattcatga
    18841 ccgaggggga taccagcaaa aacgattcca ctttctttgc caactggatt gatagaaaaa
    18901 ctaggtgtgc gcatcgaatc tcttttttcc caagagattt taggagacat ttctgctatt
    18961 tccttcgtaa attcagctag tttttgacta ttttcactat tatccaaact aacagaaaaa
    19021 acaataggag attcaatcag tgctaaatat tgttcgagat tttgtttagt ttctttgtct
    19081 aacatatcca ccacctaaat ctttccaaca agatcaaaac ttggtttcaa tgtttcgcca
    19141 ctttctttcc attttgccgg acaaacttca cctgggtggg tacgtacata ttgagcagcg
    19201 cgaatcttat caatcagtgc actagcgtca cgaccgattc catctgcatt gatttccata
    19261 gcttgaacga ttccgtctgg atcaataata aatgttcctc gctgagctaa tccttgctct
    19321 tcatccaaaa catcaaaaat acgagaaatc tgatgagacg gatcaccgat catcacgtat
    19381 tcgattttac cgatagcatc tgatgtatca tgccatgctt tgtgagtaaa gtgggtatcg
    19441 gtagagcaag aaaagacttc aacacctaaa gatttcaatg tactgtattg ttcttgtaag
    19501 tcttctaatt cagtaggaca aacaaaagta aaatcagctg gatagaagca aagaatactc
    19561 cagttcccca taagatcttt ttcactgact tctaaaaatt ctccttgatg ataagcatgt
    19621 gcattaaatt cttcgatttt tttcccaatc aatgacatag taaaacctcc aataataatt
    19681 atttatttat aattattgta atttagttgg agttgcaaag tcaatggata ttttgttatt
    19741 taataaagat tactcaaaaa cgaaggttaa ttataaaaat agaagaggtc gcaagaaaat
    19801 gctactgctg gaaatactcg ggataacgtt gagtaacagt ttcctgttct ttcagcatca
    19861 tgtgtaagtg caatcccgtt tgaaatcgag cttcttctgg ttttttatca actaaagcct
    19921 tgagtaaatc ataatgttgt tccatgatcg tttcccatgg aagcccctga atggtcactc
    19981 gtaaccagcg gaaacgttct aaatgggtat tatggtcatc taaccagttc caaacttctt
    20041 ttcttcctgc aatttcgaaa caagcttcat gaaataaatt atctgcacgg aaaaaagcgc
    20101 gttcgtcatt tattttgact gctttttctt gttcttctaa aatcgtttct agcactattc
    20161 gtgtttgtgt gtccaatttg gaacaacatt caatcatgat ttgctcttcc aactgttctc
    20221 ggacaaagcg agcattttct gcagaaacaa gattaatttt ggaaacatac gtaccacttt
    20281 gaggtatcgt atacacgagt tcttgctgac gtagttgaat caatgcttcg cgaatgggag
    20341 tccggccgat agcaagatgt tcctccagtg ccttttcaga tattttcctt ccaggttcta
    20401 agtcagcata gataatttgt ttacgaatcg cttgataagc ttgtgattgc aagctgcttt
    20461 tcatctttat tcctccaaaa tcatttctat gaacgtagta taacagaaga ggtctgaaaa
    20521 acaatctggt atgtcacatt aactagtaaa tttgtataaa tagtaaaatt ttggttgaca
    20581 tagcgatttt tattgcataa aattcacttg aatacaaaaa ctaatatgtt agtttaggag
    20641 gggaaaaatg attgatttaa acaactggag gaactttatc cctgaattat ctcaaaaaga
    20701 agtagaaata cctcattttg accgtgcatc attaagagaa aatggacaaa aaaatcctgt
    20761 ctggatccat ttcggtggcg gaaatcttta tcgaggattt catgcagaaa tcgctcaacg
    20821 tttagcggat ctaggcgaat tgtccactgg tgtcattgtt tgtgaaacat tcgatgaaga
    20881 aataattgaa agggcttacc aagattttga tgatttgatt cttgaagtgg tcatgccaag
    20941 cagtggagag ttcgtcaaac gtatattagc tgcgacagct gacagtctgt attgtcatcc
    21001 agattgttct gaacactttg ataagatgat tcgacacttt gaaaatccta gtttacaatt
    21061 agttactttt gctattactg aaaaaggtta tcgattgaaa gatacaaata ataaatatat
    21121 aggaccgatt gcagtcgata taaaaaatgg tccaaagaag ccatcacata caatgagtat
    21181 tcttgctgtg ctactttata aacgtttttt atctggagct tggccgattg cacttgtctc
    21241 tacagataat ttttcacaaa acggtagtca attacgtact tctttgctaa cgatcgcaaa
    21301 agaatggcaa aaggaaggtt atgtacaaaa tacatttatc caatacttat cgaatgaaga
    21361 aattgttgcg tttccatgga cgatgattga tcgtatcacc ccgaatcctt ccttgtcagt
    21421 tagcaaaatg ttggcaaaag agggcttttc aaatatgtcg attttccaaa ccgcaaaagg
    21481 aaataatatt gctccatttg tcaatacaga ggacatccat tatttaatca tggaagatca
    21541 ttttcccaat ggacgtccga aattcgaaaa agctggggta ttcttgactg atcgtgcaac
    21601 ggtagataaa gcagatacga tgaaggtgac gacttgcctt aatcctttgc atacgtcttt
    21661 agctattatg ggttgtttac tggggtatag gagcatagct gaggagatga aagatccaga
    21721 tttatcgctg ctagtttctg aaatcgggta caatgaaggc ctcccagttg tggagtctcc
    21781 aggtatcatt gatccaaaga tctttctgga agaagtaatt actgtgcgct tttctaatcc
    21841 aaatattcct aatatgcctc agcgaatcgc cacggatacc tctcaaaagg tggcgattcg
    21901 ttatggtgag acgattaaaa aatatatgga aatagaagtt aaagacccgc agacacttgt
    21961 attcatacca ttgactctcg ctgcttggct tcgatacctt attggcattg atgatcaagg
    22021 aaaaccattc atcccgagtc cagacccact attgacagac cttcagcata agctttccga
    22081 tattcaactg ggtacgcaag atacatcaca tattcatgag aaaatggctc ctattttgtc
    22141 aaataaagaa atttttggtg tagatcttta ccaagcagag cttggcagaa aaatagaaga
    22201 aatgttcatc aagatggtag caggaccaaa tgccgtacga aaaacattac aggattactt
    22261 acaagaacat ggaggaaatt tatcatggaa atgactttta gatggtacgg atcacaggaa
    22321 gaaaagatta ccttagatga aatcagacag attcctgcgg tcaaagggat tgtaggcaca
    22381 ttgatggata taccagtagg agaggtatgg cctagggaga ggatcaaaga actaaaagaa
    22441 gaaattgagt ctcgtgggtt aacactaaaa gtaattgaaa gcgtcaatgt gcatgatgcc
    22501 attaaaattg gattaccttc ccgtgagcag tatatcgaaa actataagca gacaatccga
    22561 aacttggcag aatatggaat agaagtcatc tgctataatt ttatgcctgt atttgactgg
    22621 gtgaaatctg accttgacta ccgcttagaa gacggctcat ccacgttagc ttttatatct
    22681 gatgatattc cagatgatcc aagagaaatc gtcgcgcgca tcgaacattc cagcaatgaa
    22741 tttggattgc cgggatggga acctgagcgc ttagctccta tcaaatcctt gcttgaagcc
    22801 tatgcatcag tagacgaaga aaaacttcga gaaaattttg cctattttct ccaatcaatc
    22861 atcccaacat gtgaagaggt aggggtcaaa atggctgtac atccagatga tccgccatac
    22921 tcgatttttg gattagctcg aatcgtaaag aatcgagaag atttagattg gttgtgtcgc
    22981 atagtagaca gcccttataa cggaatcact ctttgtacag ggagtattgc agaagatcca
    23041 gaaaatgatg tatatgggat tttagcagaa ttttgccaaa gagatcgaat cccatttgca
    23101 catgttcgaa atattaaatt tttagctaat cgagatttct atgaggcacc acataaatcc
    23161 gaatacggtt cattagacat gtaccgcata ctaaaaacaa tgtatgacat cggatttaac
    23221 ggatacatcc gtcctgatca tggaagaatg atctggaatg agacaggaag accaggatac
    23281 ggcttatatg atcgagcatt aggtgctgtt tatctaaatg gattatggga agcaatcgaa
    23341 aaaggaaaca aaagtaaaga taattagtga aaaaaactgt aattttatta tgtaaataag
    23401 aaggatgttc aaattcttga tacataaatc cggaggttgt taataagcat tcggatttat
    23461 gtatcttatt tggtctagga agtaacttga ttttcttttt tcgattgatc catgagtgct
    23521 tcttctttta attcaaagat atattctgag atcctcataa tcactttttt ccagtcttct
    23581 ggtgtgatga ttccttttaa aatatagatt tttttgatat gagaaggcaa ttgtttcaaa
    23641 gggcagtcgc tgataacgat gttgcagttc tccataaaat cattttgtat tttgatcgat
    23701 tcatttgaaa aaatttgttc tatcttaacg atcagatctt tactgatata aaaatcacgc
    23761 gtatagttca caccaatcac aattcgcggc tgttttttgt agcgatcata caaatgtact
    23821 aggtcttcaa ccatccattg cacattttcc ttttctaaaa taactggtaa caagtgttga
    23881 ttttgttctc tgaaatccat ataaaattgt tcaatggcgg tttggacttc tttcaatacg
    23941 ctatgttctt gataaagcat gaaagtagga aggggcgtat ttggttgatt gaagttaaga
    24001 aatccattat aaagtttatt tcgtgcgaat gccaatgagt aaagaatctt ttctttttca
    24061 ggtataaaca aatcaaatac agtacaaagg gactccacca tttctcttga ataaagaaca
    24121 tgaggaacgt ttgctttttt taaaagtttg tattgctcca agcttgtttc ttccgattcg
    24181 attttcgtga tagaaagtcg agctaaaata ttcactaaga tgcgttgttc gcgacaaatt
    24241 ggcagattag gtcgcaaaat atctacagag agatcaataa aaaagtcaat atattcatac
    24301 tctgtgaatt ctttttgtac gtctttcaca gaagttgcag gaaaattctc tttacatatt
    24361 tttaatagaa aatataattt atctatcata ccgctattta gtcggtcaag tacttctttt
    24421 ttaaaaaaag tattcatcat aaaagccact acttgcggat cttcatcata aaattctgta
    24481 gcagtacttg aaaagatgtt ccaataaata tctaatgctg catattgaat ttgtacctct
    24541 tttccagaaa aagactttct gccattatta gaaaaggaga tagacaaacc gtactatgct
    24601 aaaaatgcat taatcttttt cattttcgta tacaaataag aggcactata gtttgtttgc
    24661 tgactgaaac tgataatcga atttgtctga cagctgaaca aagaagtcaa gatctgataa
    24721 ctgactgatt cgttgcagta tcttccaaat agacgataat agcagtaagc cggatcaatt
    24781 ccttcaaaat tcaactttaa aaaaggtttt tgcttatcaa tatgcagttc tgttagattg
    24841 agacgctcaa agtcttgttc taattctttg atgtatagta aaaaatttga ttcagacata
    24901 tggaaatgat ctgctaaata ttgtgtagta ataaagaaac gatgttcaga taggaaaaga
    24961 aaaatatcta attttgtatt gctttttttc ttcaagataa acgttttaat cgcttcttga
    25021 gtttgcatga aagaggctcc tttttactta aattgttaaa acttgaaaat attactgttt
    25081 ttttcataaa tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt
    25141 tcttgcatac aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat
    25201 caacatttgc agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga
    25261 cagaaacagc caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg
    25321 atgaattttc atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca
    25381 tcaaagcaaa aattgactat tcgggagact tagcacctat actacaatca gctgttacat
    25441 ttgagaatgt tgatcccact ttgtcgattg gctatgacga gaacactttg actatccaac
    25501 acaagcaagc gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc
    25561 tttttactgt caaggtatca gatggactac cgaacgatca tcatttaacg ccgtatagtc
    25621 agcggcagac aattgagcaa gattcagcca tcgactcagg aggagatctt gttgaagaac
    25681 caacagataa accagaaaat gaaaataagc cagaagtacc gcctacagaa aatccagacg
    25741 gagaacagaa accggaaata gaacctggag aagaacccga tacagaaact caaccagagc
    25801 cagacaataa atcaaaacct gaaataaccc ctggagaaaa accagatgta actccagaac
    25861 cagatacgga ttctggaaac caaacagtac cggaaacaaa tccagacaca gataatgaaa
    25921 ctgaaaatcc agaaaaacca gaggtagatc cagaagaaaa accagatgtg actccagaac
    25981 cagatacgga cgcaagagac caaggaatac cagaaaaaat aaacaaaaaa acaattcaag
    26041 aggatggaaa aaaagagagt aaaaaatcaa atctagcaat tctaaaaata aatgaagagc
    26101 agctgaataa aaaatcacga atatttgata gcgcccaatc agctgaaacc ttaaaaagta
    26161 gcaaggatac aacctttgct gtcctgaaac gaaaaataaa cagctaccaa aatccggaga
    26221 gtcacaaaac aaagttatac tgtggagcgg aatcattcta ttaagtatag caacaatgct
    26281 ttctgcaaaa agatttaaac aaaacagatc tctctaacat ttgaataatg tctgtgaacg
    26341 catttttcaa ataaaaagaa atatccagaa aatgacccca aaataccaga ttgaaatctg
    26401 atatttgggg tcgttcatac tttatctttc ttcatattta ttttaaggga tatctgtttc
    26461 ttttggaaga tggttcggga tctttttcac tttcaataca tctaaaaaga aggtaaagat
    26521 cggaatgccg acaatcaagc cccaaacgcc aaagaaccgt tcgctaacaa gtaagaccac
    26581 aaatgtataa aaaatcggca gttctgtttt gctggacatc aacttcggat tcagcacata
    26641 agactcaatt agatggacaa tcaaaatcgt aatcaggata taaacaacat ctcggatgcc
    26701 tccttgggaa taagctatga aagatagagg aatacaagaa atgataacac ctgctactgg
    26761 gatcagactt aaaatgaaaa tcatgatcgc taaactcagc agctgatgaa agccaaatac
    26821 agccaaggcg attgtagtga gcaacgtatt taaaagagcg acaacaaatt gagcttctaa
    26881 taccaaacca aatgtattga caaacttatc ggcaaaatag taaatatctt gaaagaacca
    26941 agaaaattca ctttttaaaa acaatcttga gaatacaatt gtttttttct tttcaatcat
    27001 aaaaaagaaa cttaagatga atgacatagc aaacgccact gccatttttc ctatatcctg
    27061 taaatagcca agcgcaatcg aagcgccatt ttgaagctgt tcaaaaaaat cgtttcgctc
    27121 aatataagta tggatatatt gtaaaacagg atctgcatct tttggctgat gctcgtaaaa
    27181 attaataacg gactggatca tgtcaaatgt ttgatgaata agcatcggga tatactttgt
    27241 gaatgccaga tagataaggt aaacgatcag tgtataaatc atgatagcta aaacacctgt
    27301 agggattcgg acaaatcgct gaatgatttg aacaagatga atcatcaaat aagtaaagat
    27361 aaatgtgagc aaaatggttg taatcatact tctaactaag aaaagaacaa aaacgacaaa
    27421 taataaaaca gtgagacggc gtattttttc attcgccaaa aaacgctgat aaacggtcaa
    27481 atcgacaacc tccaaataac aaaaaataaa cacgttattc attatatgat ggaatatgaa
    27541 aataagaaag agcaaaaaga aaaaccgcta aatgacgtta tcttatgagt tggttttcct
    27601 cataaaatcg ttcatctagc agtttcagcc ctttttctgg tcttgatgaa aattatctag
    27661 catttttcgg gtcagatgtt gcagtgtatc caattcttcc tgttcaagtg gaagataaga
    27721 cttgatcttt tgtggaatac cttctgcttg tttttgcaac gcagcacctt gagcagtcag
    27781 cgtaacattt acgattcttt catcacccgt ttcacgctga cgattaatat aatttttttc
    27841 tgctaacttt tttagtaagg gagtcagcgt accagaatcc agacacaaat catttcctag
    27901 ctctttcact gaagtctttt tcttttccca taaaactaac atcacaagat actgggtata
    27961 ggtaagattc agcggcttga ggaggggagt gtagtgtcta atgatttctt tagaggcggc
    28021 atataaagga aaacatactt gattaactaa atatagatct tccatttttc cacctccgct
    28081 gttttactat agtgtatcat agcggattta cacaaaaaag tctattcact aactgctttc
    28141 agagtaactt ctatatttcc agctgtagct tttgaatacg gacacacttt atgcgctgcc
    28201 tctaataatt cttgcgtttc ttccagagaa agaccttcga tagatccttc aatctctaca
    28261 cctaagacaa agctcgtttc actttctgaa taaagggaaa cttgtgcact gacagtagaa
    28321 gccccagaga tatttttttg ctgtttgatc aattctaatg cactgttaaa acatgcactg
    28381 aaaccagctg caaacaattg ttcagggttg gttgcatttt cgacgcgttt accaggagct
    28441 gcaatattca attcgaatgt acgatcggga ttatgcactt ctccagagcg tccgcctgtg
    28501 ttgatcattt tcgtagaata catttttttc ataaagttac cacctttaat tatattttat
    28561 acaattgaat tttacacaat ataattgtgg aaagcaaaga aatggattgg cataagataa
    28621 ataagagaaa gcacatgaaa cagacgcgct ttctcgaata gcaaacatat acaaaaaata
    28681 tcagagacaa aaaataatct catcataaac attacatata tttctcaaaa agttgttttc
    28741 tttcttcaaa aattacttca cgatggacct gatgaagcat ccataaataa ccaaaaggat
    28801 ctctgaacat tgagttagtc acaccaaagt ccatcatttc tgtcatttct tgaatctcta
    28861 cacagccatt tcgtaatgct ttattatgtg tgtcctcgat atcagagacg atgatattga
    28921 accagatcgt atttggatgt tcagcagtag gagcagtcaa accaagagac gtgttttcat
    28981 ccagcatatg gaatctcgta ccatacaagg taaaaatgac ttcattattg cctctagggt
    29041 aatctgttgc ctcaatcagt tgtatttcat caaagattgt ttgatacagt tctagtgctt
    29101 tcaaactatc atttaataca aaatcgattt ccgttccttt atgcataaag atctcctctc
    29161 cttttcagtc gaacagttac tagattcttt tattatacca gctaaagaaa acgcattcaa
    29221 aaaaatagcg gatttactta ccaactcatt cgattggatg ataagtaaat ccgcgtccca
    29281 ttacttctgc tacgctgctg acaatgacaa aggcacttgg atcgatttct tctatcaatg
    29341 gtttcattcg ggaaaattca tgatcagtca caacgatcaa taaaacctct tttgactttc
    29401 gattataccc gccttttgcc tctagcaggg taaggccacg tccaatctca gcacttaagc
    29461 gaaggcggat gtcttccaaa taatgttcac tcatgaccat aacagatttc tttcgattga
    29521 tacctgtttc gatataagtc atgacaattg aagtgattgc aatagataaa atagcataaa
    29581 gaaactcttc tattccaaaa ataaacagat taagagaaac aacgaatgcg tctgtaaaaa
    29641 ataagccaat cgaagtattc aagtggaaat attttttaaa aatgagggga gggatcgtcg
    29701 taccgccgct agaagagttg tttttatata aaatcgcaac tcctaaagca aaaatcgcac
    29761 ttccaaaaat gacagacaac aaccgatctg aagtaatcat tgtttctgga actattgcaa
    29821 tgattaaagg aaaaaccaag cttccgaaaa gtactttaaa aaagggtttt ttacctaaaa
    29881 atagaagagc tagtaccaac ataacgatat tcaacactaa aataactata gctcggtcaa
    29941 agcctaaagc agcttccagt aatattccta gaccgctgac acctccagca gcaatatgat
    30001 gaggccctaa aaacatattg atagcgactc ctaatatgaa gagggcaaaa ataatcttaa
    30061 tgtatgtcca tataaattgt ctcgtttctt tcatttattc acttccttaa ttcattaata
    30121 atactcttat cttattataa cttacttttc accttaagtt aactttaatt aataaaaaaa
    30181 ttaggctagt ctaaattatt atgtttcatt cttctagaat atacttctac gccaaaaact
    30241 gttaaaaaac ttttacttta gaaaattgga gaaattgatc gcttaagata aattcaggac
    30301 actaaatagt acaggaagta gactaaaact tttaaaagtt ttaagtctat ctatttggca
    30361 agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc gataacattt ttgaaagcgt
    30421 tgtcttttgc ttctctatca cttatagtga tgacgtcata ttaaaacaca aggaggaaat
    30481 caatggatac agctgcaatt tatcatcgac cggaaagtga atatgcattt ctatatacga
    30541 atacaagatt tcgtattcgg cttcgtacta ggaaaaatga tatcaaaaaa gtatatgtgc
    30601 tatgtggaga tccatatacc ataacaactg aaaaatggta tcaaaaacaa cgaccaatga
    30661 aaaaatgtct aagtaccaat gttcatgatt attgggaaat tgaagtgacg agcgaaacaa
    30721 gtcgcttaca gtatgcgttc catgttgttg gggaagataa cacggactgt ttttacggtg
    30781 atcaaggaat ttttccttat cgagaaaatg tgattactga accaaatttt tattttcgaa
    30841 taccttattt tcatcaaatc gatcgattca ctattccaga atgggtaaaa gaaacagtat
    30901 ggtatcaaat ttttcccgaa agatttgcaa acggggacaa agcaaatgac cccgaacaca
    30961 ctttaccttg gggaagtaaa gatccagacc gagaagactt tttcggggga gatttgcaag
    31021 gtgtgatgga tcatttggat tacttgacgg accttggcat caatggcatc tatttttgtc
    31081 ccatatttaa agccacatcc aatcataaat acgatacgat tgattattat gaggtggatc
    31141 ccgcttttgg cgataaaaaa cttttaaaaa acttgattga tgaagcacat aaaagaggga
    31201 tacgtatcat gttcgatgct gtattcaatc atatgggtgt ccattcacca cagtggcaag
    31261 acgttctcaa aaacggagaa aaatcgatct ataaagactg gttccacatc cgttttttcc
    31321 cagtagattc ttatcagatg actgacttac cagaaactgc tgaaaatatc ccatatgata
    31381 cttttgcttt tactccattc atgccgaaac taaatacagc aaatccagaa gtgcaaaaat
    31441 atttgctgga tatcgcaact tattggataa aagaattcga tattgatgga tggcgtcttg
    31501 atgttgctaa tgaagtcgat catcattttt ggaaaaaatt cagagaagca gttacagaaa
    31561 tcaaaccaga catctatatc cttggagaga tttggcattc ctctcaagct tggctgcaag
    31621 gggatgaatt ccatgcagtg atgaattatg catttacaga ttcgattaaa gattattttg
    31681 caaaaaagaa aatcacagct tcacaaatgg tcagtggaat gaatcatcag caaatgcttt
    31741 acagagatca ggtgaacgaa ggaacattca acttattaga ttctcatgat actgccagga
    31801 tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc tgtgatggcc tttatgtttc
    31861 ttcaaaaagg gtctccttgt atctattacg ggacagaaat agggatgact ggtgaagatg
    31921 acccggattg ccgcaaatgt atgatatggg agaaggagga acaagatcta gagctattcg
    31981 gttttataaa agaacttgtt tctctaagga aacagttgtc taagattatt tctgaaggtt
    32041 ctactcagtg gctaatagta aatgatcgtg aagataagct ctatttcaca cggaaactag
    32101 agggacagat catctatgtt tactttaatc agtcaaaaga accttgggta gtagaacagg
    32161 aaaatgaggt gattcttagt caaaattgtc agttgttaga agacgggaaa gcagagatac
    32221 gacaatacgg atttttgatc atgtgttgaa aactgttacc ggtaacaaca agaaagcgtt
    32281 tgcaaatgaa gatttgtgcc cattataata agggtgtaac agcacgttga atacaaagga
    32341 ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt ttagggttaa tctctttagg
    32401 aatcttaggc ggattagcgg cttgtggcaa tggtaactct tcagcagaag gggaagccga
    32461 tgaaggaaaa acgttaacag tttccgttga ttctggatat aaagattata taaacgaaat
    32521 aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag ctagtagaaa aggacatgtt
    32581 cgatcagttg gaatcattag cgttagatgg gcctgctgga aagggacctg acgttatgat
    32641 ggcagcatat gaccggatcg gtgcgttagg acagcaagga catctggcgg aagtaaaact
    32701 gggaaatgaa gcagcttacg atgaaacaga caaagcccaa gtgacttatg atggaaaaat
    32761 ctacggagaa cctgcagtaa tcgagaccct tgttttgtac tataacaaag atttagtcga
    32821 tacagcacca tcaacgttta aagatttgga gaatctatcc aaagacagtc gttttgcttt
    32881 tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa tggactgact tttattattc
    32941 ctatggttta attgcaggtt acggtggcta tgtatttggt gatgatggca caaatccttc
    33001 agatatcggt ttgaataatg caggtgctgt agaaggaatc tcttatgcaa cagattggtt
    33061 caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt gcaggagact tcgccagcca
    33121 gcaattcatg tccaataaaa ctgcagcaat cattgacggt ccatggcaag cgcaaacata
    33181 caaagaaaac aatatcaatt atggtgtagc caaaattcct actctaaata atggacagcc
    33241 ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc aattatgcta aaaacaaaga
    33301 cctctctcaa aaatggcttg attatgtaac gaatcaggaa aatcaagaaa aattctttga
    33361 aatggtaaat gaaatccctg caaaccaaca agctagggaa acagcaaagg ctaaaaacga
    33421 tgaattaaca acagctgtga ttgaacaata tgaaacagct caagcgatgc caaacatccc
    33481 agaaatgggc gaagtttgga caggtgcaga aaacttgatg ttcgatgcag catcaggttc
    33541 aaaaacacca aaagaatccg cagatgaagc agtaaaaaca atcagtgaag ccatagaaca
    33601 aaaatactga ttaaaatgat aaccgtccat ttttataaaa aatggaacag gtgcttcaga
    33661 taaaagtggc aagagcgaga tggaaaatta tcttgctctt gttgccatta tcttaaaagc
    33721 agtttgcggt ttagcaagtt tagagggggc attcagatgc agcaagataa aacaagcaat
    33781 atcaacgaaa aaaaaatcac gctttgttca cttattccag ggatggggca gtttgtaaat
    33841 ggccaagctt ttaaaggtat cgtttttttc gccatattcg tcctattcat tggtcagatg
    33901 cttctgggcg gatttcatgc attggtagga ttggttactt tgggaagtat accaatggaa
    33961 gatcattcat tatttatttt gattgaaggc actttgcaat tcatcattac aatcattttc
    34021 ttgatttttt acggtttgaa tcttttagac gcttatcgag tagcgaagat gcgtcaagag
    34081 ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata atataggtga tgaaggtttt
    34141 ccttatctat tgacacttcc cgcttatctt ctcatgattt ttacgatcat tttcccagtc
    34201 ctagttacat tgttcactgc atttactaat tatgacttca atcatattcc accagccagt
    34261 ttaattgatt gggtaggggc taaaaacttt tttagtatct tctttttaag ctcatatcgt
    34321 aatacttttt ttgcagtctt ttcgtggacc gtgatttgga ctttatgtgc aacaactttg
    34381 caaatcaccc ttggtattct cacagcggtt gttgctcacc agaaatttat taaattcaaa
    34441 cgtattttcg gtatcatttt cttattacca tgggcggtcc cagcttttat tactatcatg
    34501 agtttttcga atatattcaa cgatagcgta ggtgccatca atactcaagt gattcctttc
    34561 ataaaccagc ttccttttgt agatatcagt gcaatctctt ggaaaacgga cccgaactgg
    34621 acgaaagtag caattatctt agtgcagggc tggttaggat ttccctatat ctatgtgatg
    34681 gttacaggaa tcttacaatc gatttcagaa gacttatatg aagcagcaaa aatcgacgga
    34741 gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg ctgtcttcct agtggcagcg
    34801 ccaacattta ttacacagta tacggggaat ttcaataatt tctccatgat ctatctgttt
    34861 aacaatggcg gtcccggaag cgtaggcgga ggagctggtt ctactgatat tcttatttcc
    34921 tggatctata aacttacgac tggaacttct ccgcagtatt ctatggcttc agcaatcacg
    34981 ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg tatttaaaaa gacaaatgcg
    35041 ttcaatatgg gggattaaca atgaaaaaat ttcattcgag tgctcgattc caaaaacgac
    35101 tttctcactt ttttacttac ttttttcttt taatactgtc agtcattatc atctatccgc
    35161 ttttgatcac agcaagtact gccttcaagt caggaaatat tgcagctttt agtttagatc
    35221 tttcaagtga ctggacttta ggaaacttta ctcggctatt cagtgaaaca ctttacggga
    35281 cttggtataa aaatacattg atcatttctg tcctaacaat gatcgtacaa gtgactgtag
    35341 taactttggc gggctatact tatagtcgct atcgttttat cggccgcaaa tcaagtttga
    35401 tgttcttttt agtgattcag atggtaccga ctatggcagc attgactgcc ttttatgtca
    35461 tggctttctt attagaagcg ctcgataagt actggttctt gacaatgatc tatataggcg
    35521 gtggaattcc aatgaatact tggctgatga aaggatactt tgacactgta ccaatagatt
    35581 tagatgaatc tgctaaactt gatggggcag ggcatttcag gatttttttc cagattgtat
    35641 taccgcttgt caaaccgatg ctcgccgttc aagcattatg ggcttttatg ggaccttttg
    35701 gggatttcat gttagctaag ttcctgcttc gaacacctga aaatcagact gttgctgtcg
    35761 gcttacaaac atttatttct gatgtgacaa accaaagagt ctctcttttt gctgctgggg
    35821 caattttgat tgcactaccg atttgtctat tattcttctt tttacaaaag aactttgtta
    35881 ccggcctgac atctggcgga acaaaaggat aggagcagag tatcatgcaa acatttccgt
    35941 taaactattt ttccgcatta cgtacgccaa ctcaagtgtt tgcgggacgc aaactattat
    36001 catggcctaa atttttcttg atatttgtat ttttagtttc cttgatggtc atgcctgtga
    36061 ctctttttta tgccaatcag atccaagcga ttccattaga acaatttcta tccgttcatt
    36121 cgctgatcga tgaacaagga acccaaaaat tttctgaact tgaattatct gaaactgggt
    36181 tacaagcatc gcaacaaacg atagctgtga cccctgaaat tttggtaggt gtgtctttat
    36241 ctgagaaaca acaatccgat catggaactt ttattgattt tgagaaggaa caatgggtga
    36301 tccaacaaaa ggataaatct ggtatacgcc gctatacgat gaattatagc ccatctttcc
    36361 aaccagattc tgtacgtacg cccgaagatt tccaacgatt tttagaaaga gaattttatg
    36421 ccagtaatcg tccaacaatc attttatctt atagtttaag tcttggtctt gtcctatttg
    36481 tcatgacgag tctcatttta ttcggggctt cctttttctt gtggatgaca agaaaaagcc
    36541 aactttcatc cattcataca ttcaaagaga gtgcaaattt gatgctgaat gttatgggaa
    36601 taggttccat ggcagcagca gttgtagggt ttatccactt tgactttatc ttgatgctaa
    36661 gtgtccaaac aacgataact gtcttgctgc ttttatgggt ttttgtcaaa acaagattca
    36721 aagataagcg tgtcgaatga caagtttaag cgatttatgc gacaatgaat gtgaaaaaaa
    36781 tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt aaacttctta gttgattctt
    36841 ttctttttta gtattaacgt aatagggtag tttttttaag gaggaaaatc atgttagaga
    36901 aaactttata caatcaatta ttttcacgtt ctttctcgct ccctgtcgaa gtaaattatt
    36961 gggacggtac aacgaaacaa tacggagata cggacactcc tccccaaatc aaaatcaata
    37021 tccatgaaga aatcccaatg aaagagatta caagtaacgc ttctttggca ctaggagaag
    37081 cctatatgga tcatcgaatc gagatcgagg gaagtatcca agcattgatc aacgatgctt
    37141 atcagcaagc aaacagcttt ttacgaggaa aagattatct aaaatggctg ccaaagaaag
    37201 aaaaacatac gaaacaaaaa aacaaagaag atatccatgc gcattatgac ttaggtaacg
    37261 acttttataa actttggcta gatccaactt tgacttattc ttgtgcttat ttcaatacac
    37321 ctgaagatac gttggaacaa gcacaaatca ataaagtcca tcatatctta gacaaactct
    37381 ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg ctggggaaca ttgatgttca
    37441 ctgctaccaa agagtataat gtcaaggcaa ctgggatcac actaagtgaa gaacaatacg
    37501 atttgattac caaaagaata aaagaagaac atttagaaga taaatgccgt gtattattaa
    37561 tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat cacaagtgta ggtatgttcg
    37621 aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt ggtaaaagat ttattgaaac
    37681 caaaaggaac agctttgatc catggaatca gccgacaaca aggcggtgcg acaaatgctt
    37741 ggatcaataa atatattttc cctggcggtt atgtccctgg tgttactgaa ttagttgata
    37801 atattacaaa aaacgatttg caactgattg atttggaaag cttacgtcgt gactaccaat
    37861 tgacattaga acattggaca aagaattttc atcaagtcca agatcaagtc acgaaagaaa
    37921 tgggtgattc cttctatcga atgtgggatc tatatttaca agcttgtgca gcttcatttg
    37981 aatcaagtaa tatcgatgtg attcaatatt tgcttgttca acctggaaac aatgacatcc
    38041 caatgcatcg tgcataattg aggcaaaagt actgtttaaa gactatttaa aaagaagcta
    38101 agttttatga tgctccagaa gtgaactttt ttgtctaact tctaggattg tctctaaagc
    38161 ttagtttctt tttctttata ttttcataat aaaagtttgg ttctttaatt tttaaacatg
    38221 acagaaaatt ttttcttcgt tatacttgta atagaatact attttataac aaaggggatc
    38281 gaatcaatga aaaaaactgt tatttatact agtttatttg cagctttgtt tttagctgct
    38341 tgtcaatcaa ataccaatca aggcacatct gggaatacgt cttccagtag cgaacagcgc
    38401 tcttcacagg tatcggactc ctcaacaaaa gcaagcacat cttcgtctag ccagacaaaa
    38461 agttctagtg aagcaagtac tcagtcagat atcaaagtgt ctgcagctcg tgcgatcgaa
    38521 ttgttccaag ataaataccc agatactgca attactagtt tggaattaga tagtgattgg
    38581 ggatcttact tctacaagat agaaggtgtc gatgatcaaa aagaatacga agcaagaatt
    38641 gatgctcaaa atgaaaaaat ggagacagag aatccagaaa ctctagatcg agatgaacaa
    38701 aatggtcaaa agaaaaaaga agatggtctg gatgttgata aattgatcac gattgaggaa
    38761 gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg caacagattg ggatttggat
    38821 aaagatttag gtactactta ttgggaagtc aaagtaaaag acggcaatca aagtacatca
    38881 gtcaagatca atagccaaac aggcgaagta ctgtcaactg aacaagatga ttaagaattt
    38941 cttcggaaaa caagagttga tttttctttt agtcatgata cactagacaa aataacttgt
    39001 ttgaaggagc gatttacttg agtttagaaa cgacctttgc caatcatatc tttgccaatc
    39061 ctttgatgaa tgcatctggt gtccactgca tgactaccca ggaattagat gaactggctc
    39121 attcagaagc aggagcattt atcactaaga gctgtacgat caatgaacga aaaggaaatc
    39181 ccgaaccacg ctattttgat gttcctttag ggagtatcaa ttctatggga cttccaaact
    39241 taggtttttc ttattatcta gagtatgctc ttgcgtatga aaaagtgcag gaaaaccaaa
    39301 atcaaccgtt atttttttcc attgccggga tgagtgtcca ggaaaacttg gaaatgcttg
    39361 agaaaataga aaaaagtggg tttaatggga tcactgaatt aaatttatct tgtcccaatg
    39421 tgcctggaaa accacaacta gcttacgatt ttgaggccac ttatgaaaca ctgaaagaag
    39481 tattcagcat cttttctaag ccgctaggaa tcaaattgcc tccttatttt gattttgctc
    39541 attttgatca gatggctgat atcttgaatc agtttccatt gacctatgtc aatgctatca
    39601 acagtgtggg caatggtttg tatatcgata cagaacaaga agcagtagtc atcaaaccaa
    39661 aagaagggtt cggcggcatt ggcggagagt atatcaagcc gactgctttg gcgaatgttc
    39721 gcgcttttta tacacgtttg aaaccagaaa tccaaatcat tggtacaggt gggattcgga
    39781 caggacaaga tgcatttgaa catctgctat gtggcgcaag catgttacag attggtaccg
    39841 agcttcataa agaagggccg gaaatttttt ctagaatcat aaaagaatta acgcagatta
    39901 tgtcagaaaa aggatatacg tcaattgacg aatttaaagg caaattacgc accatttcat
    39961 agcaaagaga cgaaggtcat gattgatctt cgtctttttt tataaaaaac actcgtctgt
    40021 tcattcctgt gcaagcgtac tcattgtatg ttagacgaac ttgtgggaaa ataacagagg
    40081 caaaaaggag gataatatga atgatgcaac agaattagca aaagagctta aagaaaaaga
    40141 atttagtttt caagaactag ttacggatat acagaaaaaa ataaagaagc aaaatcatga
    40201 attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat tcccacgagc tattgattcc
    40261 ccagtcagaa aaagggccat tggctggtat cccatttcct ttaaaaatgc tcggtcaaga
    40321 aaaaaaggga tggctagcta cttcaggatc tcgtttattt gaaacacacc gagcttctca
    40381 tacatctaat tatgtgcggc aagcagaagc gataggtcta gttccttttg gacaaaccaa
    40441 tgcgccagag tttggtttca aaaatattac agacccagtc atctatggcc cagcaagaaa
    40501 cccttggaac cttgaatgta caccgggcgg atcaagtgga ggagctgctg ctgcagtttc
    40561 atcaggaatc gttcctttag ctggtgctag tgatggcggt ggttctatta gaatacccgc
    40621 ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg acgatgccag ttggtccata
    40681 tgcttggaga ggatggcaag gagctgctat tgatttcggc ttgacagttt ctatgagaga
    40741 cacggaggct ttattttatg ggatgagaag tatccattcc ggtgcgccat atcaagtatc
    40801 gccagttgag tggcaaacac atccaagaaa aaaacggttg aagatagctt tttgtgttga
    40861 ttcaccgatc cactcacaga ttagtgaaga ggcagtactt gctgtaaaaa aagctgtaga
    40921 tttccttgga aaagaagggc atgatttgac agagattcct tacccactag atggtcgtaa
    40981 actgatcacg tcttattatc agatgaatgg cgcagaaaca gcagcaatga tccgctcgat
    41041 tgaaacaggc atccagcgag ctgtcagaaa agaagaactt gaacccattt cttggacttt
    41101 gttccaatat ggtcagaagc tctctgccgc tacttacatc gattctctgc atgtatggga
    41161 tgaagcagca attgtcatgg aaaacctaca tcaagaatac gatctattcc tttcaccaac
    41221 gactgcattt accgccccta aaatcagcga agatttgcaa agtgatgcga taagagcaca
    41281 gatggaacac atcagtgatt gttctgaagt agaaggttta gacgttgttt cttccatgtt
    41341 tgaggagagc ttgaagatca caccttatac acagttggct aatctgactg gacaaccagc
    41401 aatcagcttg cctactcatt tgacaaaaga aaacatgcct ctaggaatcc aatttatggc
    41461 tgccagagga agagaagatt tgctatttca aatcggctat ctatttgaag caaatcatca
    41521 gttccattta ccaaatccat ggaaatagca gaaacaagga gaagaagaat gaagaaaaaa
    41581 agattgtttg ctctaataac tagtgccttt tttattttaa gcgcttgcgg tacagctgcc
    41641 gctaatcagg aagataacag ctggagtaat gtagaaaaaa agaaagaatt agtagtagcg
    41701 acttctggca cactgtttcc cgcatcttat tataatgatc aaaatgaatt agttggttat
    41761 gatgtagatt tggcaaaaga ggtggctaaa cggttaaatg tcaaaatctc ctttaaagaa
    41821 tacaacgtgg atggacaaat cacttctgtt tcaaaaagag aatcagattt tgctgcgaac
    41881 gattttggta tcacaaaaga aagagaaaaa aaattctccc tttcagagac tttcaaatat
    41941 tcatttgaca gtatgatcgt acgaaaaaaa gatgattcag gaatccactc acttgaagat
    42001 cttaaaggga aaaaagcagc tggcgaaccc aatactagct atatgcgttt agcggaaaaa
    42061 cacggagcta aattagtcac atatgacaat gccacgaatg atcagtattt aagcgatgta
    42121 gcaaatggtc gaacagatgt tattctaaat gattattatc tgcagaaaat ggccgtatct
    42181 gctttaccag atatccctgt aaaaatactg gagaacgttt atttcaatga aaacgaaagt
    42241 ggttttttat tgaaagaagg aaatgatgct ctgaaaaaga aaatcgatgg cgtattaaaa
    42301 gagatgaaag aagatgggac gacaaagaaa atatctgaaa aatattttca aactgatgtt
    42361 tcagtcaaac cgaaagaaac gatggctgag tcggtgagtg agtgatgtac tttcctctaa
    42421 ttgatttttc cctcatgtgg acttcacttc ctttcgtact gcaaggcttg gtatacacat
    42481 tagggattgg cttcgtgtcg tttcttttag gaaatctggt agggttgctt ttgacagttt
    42541 taggtctttt ggattggctg cctctgaatg tatttattcg tttttattta tcgttcttta
    42601 gaggcattcc cgcactagtc ctgctgtttc tgttatattt tgggttacct tatcaattaa
    42661 gtgccttaac ggcttcagtc atctgcttta cgattaccag cagtgcattt attggtgaaa
    42721 tctatcgagg atcactagca ggcgtttctt caggtcagtg ggacgctggt ttagcttctg
    42781 gtttttcttt ctttggggta ttgaaatata tcgttttgcc gcaagctttt cgaatctcag
    42841 taccggcact cagtaacgta gctatggatc tagtgaaagg tacttcgtta gcagcaacaa
    42901 tcacagtgcc agaaatattt caaaaagcaa agatcatagg cggtcggaca ttcgattatt
    42961 tttctctcta tattttagtt gcactgattt attgggtcat ttgtatcggg atcgaaaaag
    43021 tgcaacagta tttagaaaaa cgttctatgc atcagtcaat ctgaaaaata gaaatggtgc
    43081 tagcgtggct ggcaccattt ctattttttg tttcttgtat attctgccta gtattttaaa
    43141 accatttcat gtaaaatgta aatcgaaaat atgttcggag gtagaaaaca tgaagacccc
    43201 gctaaccatc gaaatagaat cctcgttata ccaatattgc atcgagcaag gcggcttggt
    43261 tgtagaagaa gtcacgatgc ctgatgacca aggaattgta gatacgctta gctgcttgac
    43321 aaaatttgat ggaagccgag aatggcgatg ctatgagctg aaagtgacaa aagcagattt
    43381 tcgctctaca gccaaactgt catttgttgg acattataat tattttgttt taccaagtaa
    43441 actatatgaa gaagtaaaaa ctgaaatccc tacaggaata ggtgttttag tgtatcgtcc
    43501 gtacacggtt gaagaggaga tgcctgcctc tggtacattt ctgattgcga aaaaagcagc
    43561 aaagaaagag cttgctgtac cggaagaagc tttgacaaac cgcttcatgg cttctttatt
    43621 cagggaagta agaaaagcaa agcaaatgga gcgaggcgta aaatattttc caacagatca
    43681 attgtacaaa gaattgaaaa gacgttcaga aaatcaagat ccattttcta acgaacgata
    43741 ttatgaacgg tttttagagg aaatagctag tcaggcaatc aatgagttgc aagaagaagt
    43801 tatcgcgctt cagcatgatt atgaatattt gaggcaacaa cagcagatcc gtcggttgcc
    43861 tacagagcca ttggagtgaa aaatatgtac tatccttatt taagaggaaa acaatttgac
    43921 ctattagcat taaaagaagc actgtcgcga ggattgctct ccaataaaat ccaaccagtg
    43981 atcgaaccag tacgtgattc cgctacgctt aaaaatgtga tcgaattatt tcaaaaaaag
    44041 caccatccaa tcgctgtgat ccaaaatccc caagtaggac aattcaaatt attcgatcag
    44101 catgtgcaca gttggacagt caaagaaaat agctctgtcg tccctgcaca gatcttaacg
    44161 ccagaaaatc tcagtgaagt actggattca cctccagcgt ttcttgtttt cgatggacag
    44221 cactacccaa aagatacaga ggtgtggaaa cagttggcag gagttgattc gaaatttttg
    44281 ataccagata ctagtcgctt tcgcatctgg ctgcccgaaa acaaaattgt gatccgtgac
    44341 tcttttcaaa cgagaaagca tgttgaaagt tatgcagata aaacagatga cttttttagt
    44401 gatgactatc tttttttcca cgcagacgga tatattggat tttctgattt cacgatcgaa
    44461 ggtagccgtt atttcgataa agggttccct agccgagcgc ttgctatcca tctaacgtat
    44521 attgatgctt acggcaatat acgcgtgaaa cattttgtct ctgacagtaa cgactctgct
    44581 aaagaccaag cattgaagtt tcttgaagca ggagataaaa tgaaaaaatg gatcatgcgt
    44641 caccatcatc aactcttgat tacttcagga atgattgaat tattggctct ttaccagcaa
    44701 caaaaattcc ctggactggg agtgttgaaa aagtggtcac ttatgcatca tttggaactt
    44761 attagtcacc tgctagatca tccaaaagat tggcttaaat attattcaaa agttcaggaa
    44821 ctatatgaag tgatccaatg attagataat gtaaatgaaa aaggaataga aaagaggaaa
    44881 ctggatgtat attcggcaaa caaggaaaga agaagtagaa gaagtggtag aaatcattaa
    44941 tgccgcagcg gatttcattg cttcgcaagg ctctcctcaa tggcaaaacg ggcagaaacc
    45001 aacaaaagaa acgattttga acgatattga aagaaaagaa agctatgtat taatagtgga
    45061 agatcaaatt gctggaacag ctgcattagt ctcaagcgtg gatcccgttt acacaaaaat
    45121 agatggtagt tggaaagaat caactggtcc ttatttatcg attcatcgtg tcgctttagc
    45181 agaaagtact cgaggaaaaa aactagcaaa accgttctta gaacatttgt tgacgattgc
    45241 agccagcaaa aatatccaag atatccgtat cgatacttat ccagctaatg aaccgatgga
    45301 aaagaccatc tattctgctg gattcactta tcaagggatg attgaatttc cttttgaaca
    45361 cggcgaaaga aaagcatatc aaataatcat caattgacta taaaatcatc tgagcaaaga
    45421 taaagacatt aacactactg aaaaaaacaa tcatatgata gccaagaggt tgtaacagaa
    45481 gtggccagct tcaaaaaaca agaaagaatt tccgaaaatg cttctcaaat ttttgtggaa
    45541 ttttagcgta ttttacgaaa tagctgcttt ctgaaactcc cttcatcgag aggtcgtgac
    45601 atagcttttg tcacgacctc tcggcttatc ctacgagtat tattcgatac atttatatca
    45661 ataatccttt ttttatttta tctgcagctt cttggaacgc tccatcgttt gacacgacta
    45721 aaagtgaggg gatagctttc aaacgtttca actgtgctaa atcttctaca taaaccgcca
    45781 gtctggctga aatctgttca gatgaatctc cacgtttttt caggcgcgat tgcaatgttt
    45841 ctttagagat cgtaataaag ataggacgga ctaccgtccc gaaatactca tataaatgcc
    45901 aaaaaccatt tgctgtcaaa acggcgtaac aatttcctac tgtcagtttc tttttaattt
    45961 ctgctttact ggaaccatat ttatgttgag catattggtc ccactctgca aactcatttc
    46021 ccttgatcat ctgattgaat gtattgtcag aaacaaaata ataatcctct tgatcttttt
    46081 ccccaggtct tggtgatcga ttcgtgtaag taatgatctt ttgttccggc tgaaaaatag
    46141 cttctgcgag tgaagttttt ccagaaccag aaggaccgat aaatacatag caataattca
    46201 ttgtcatttc tcctttgatg attgaacaag tgaaaaagct ttggaaaata tttccaaagc
    46261 ttttaaaagt aactttgctt ttttgtatat tataccagca agccagtcac aatagcactt
    46321 aaaaagctga ctaaagtcgc tgttagcaaa attttcaatc cgtgttttgc gacaagattt
    46381 cctttttctt catttaatcc cttcatcgca ccagaaatga tcccgataga agagaagttg
    46441 gcaaatgaaa cgaggaagac agatataatt gctgttgtac gctcagtaaa atggaaatta
    46501 ccatttgcta attctgtcat agcaacaaat tcatttgtaa ccagtttagt cgccatgata
    46561 ctaccggcat ccactgcttc tttccatggg attccgctga tgaaggcaag aggggcaaag
    46621 atgtaaccta ggatctcttg gaaagtgatg ccgaatatcc cgtggaagat agcattgatc
    46681 atggcaatca aagcaacaaa accgataagc atagcagcaa ccgtgatcgc cacatggaaa
    46741 ccatcaagaa tgtattctcc caacatttgg aaaaatgtct gttctttgtt ttcttcaatg
    46801 atcagctcat cttctttttc ttctaataca tagggattta caattgaagc cagaatataa
    46861 ccgccaaata agttcaaaac aagggcagtg atcacatatt tagaatcgat cagtgccata
    46921 taagatccga cgatcgacat agaaactgta gacatagccg atacactcat ggtgaacaaa
    46981 cgtttctcag ataggaaggg taattccttt tttatggaaa taaaaacttc cgattgtcct
    47041 aaaatagcag aagctactcc attataagat tccaatttgc ccatcccgtt gattttactt
    47101 aatcctagac caacagcttt cataaataat ggaagaatct tgatatagcg tagaataccg
    47161 ataatagcag aaataaatac aattggcatc aatacggaaa gaaagaaagg tgcacttcct
    47221 ttatttgcta caccggcaaa aacaaagtca acaccttgcc cagcaaaagc aagaagatga
    47281 tcaaacattt ttgccaatac agaaacaacc gctgtaccaa aagttgtacg taataatacg
    47341 aaaccaagaa caagctgtaa aacgaacatc acaattagtg gtttcaattt gattgctttt
    47401 ttgttactgc tgatcaaaaa agcaagccct aatgtgacaa ataaaccaat aatacctaat
    47461 aaataactca aataatcact cctattccaa attccgtttt attttacctg ttttgcaaat
    47521 aaaatactaa tctttagtga aattttcatt acttttttag agtgaaacgc attcattttc
    47581 cattagaaaa taaagcgaac aaaataaaag gtttaaaaag tgtaacgtct tagtaaagtc
    47641 tataaaaaaa cgaaactatc gattaagcta atagtttcgt tttcaacatt tataagtaaa
    47701 ctttttctat tggtaatata gattttcgga agggtagaca ggtgcgcagg taatatcgat
    47761 tcctagtttt ttcaatgttt gttcatcatt tttattgacc atcacagtag agtgggcttg
    47821 tgctccctca agttcagcta gtttatcata agcaacttga gcgattggat tcgttactgc
    47881 actgattgat aaagcgatca agacttcatt gatgcttagt gcatccaaag aggaatgaag
    47941 tgtctttgat ttcaatcctt gtattgtttc aagaactaat ggtgacaata aaggaatgtc
    48001 atctgcgata tgggctaaat gttttactgc atttaagata actgccgctg acgcatccat
    48061 caatgaactt gtacgcccgg taatgatgac ttcatctggt aattcgattg caatcacagc
    48121 agaaggatct tttgtaggac tttgcgcttg aatcttatct gcatagtcat gggcagggac
    48181 taccacgttt cggtcttcag gacgtaaacc gacttcttcc ataatcagtt tgattcgatt
    48241 aactgcttct tcgtcgatca atcctttttt gaagtcgcat tctgtttgga aataacgacg
    48301 gatgatttct tgtttagagg cttcttggac aacggtatca tccacgatcc caaatcctac
    48361 acgattcaca cccatgtcag taggagattg ataaacagat tctttaccag taattttttc
    48421 aataatacgt ttgattacag gaaatgtctc aacatcccga ttatagttca cagctacttt
    48481 attgtaggca tcaaagtgga aggaatcgat catattgaca tcttttagat cgactgtggc
    48541 tgcttcataa gcaatgttca gcggatgttt caacggaaca ttccatactg ggaaagtttc
    48601 gaacttggag taaccagctg catgtccttt ttggctttca tgatacagtt ggttcaagga
    48661 agtagcgagc tttccacttc ctgggccagg agctgtcact acaacgattg gtttagttgt
    48721 ttcaatatac tcattttttc caaaaccatc ttctgagacg attttttcta cgttgactgg
    48781 atagtcttcg atttctgagt gtttatagac cttgatgttt cgtctttcta gtttattgat
    48841 aaagactttc gtggcaggct gtccactata gcgagtgata acgacactgt tgattaataa
    48901 gccataacca cgtaattcat cgattaaccg caagatatcc atatcataag taatcccata
    48961 atcaccacgg atcttattac gttcaatatc tccagcatag acgcaaatca gtatttcagc
    49021 ttgatctttc aatttttgca gcaatttgat tttcgcatct tcttcaaatc ctggaagtac
    49081 acgtttcgca tgcttgtcgt caactagctt cccaccaaat tctaaatata atttgtcata
    49141 gtggttcact cgttccaaaa tatacgctga ctgctcttca atatattttt ctgaatcaaa
    49201 accaattttt ttcactaggt tccctcctta agtactaaag cattttttca tttttttgag
    49261 gattcgtcaa ctggaagagc gaaattcctc aaaaaaacaa agaaaatggt ttaaaccaac
    49321 ttgtctagat agttattcat tggtatgata gtttttgata aggaaggtgc tacatgaaaa
    49381 aaagacagaa aaagaaaaac gcatataaac actatatccg ttcgattttt accggttatg
    49441 aaagaatgct tgaagatccc gaattggaac aattgacgtt tacttatcta aacgaagaaa
    49501 cgcagctaac tcgtgatgag catcagcgca ttcatttcac aacaagagat ctgcctagta
    49561 aataaaaaat aagataaagg tcatcggatt cgattctgtc ctatcagatg gaaagactag
    49621 ttgatcgaaa aaaaggctgt accaaatttt ggtgcagcct gttttatgga gcattgcccg
    49681 ctctttttta taacaatttt ttacagaaaa tggtactatt gaagtattaa taagtgaaaa
    49741 acagatgagt aagaggaggc aagtagtatg aaagagccag atacaaatgc aaattatgag
    49801 ccagacgaac tagaggagac gaatgcggat caggatacag gacaagaatc gtcttctttt
    49861 tacgatatca aagaaaaagc aagcatgaat ctttcccaat tattagaaga cttacaggct
    49921 tttgaaaaag ctgtccgcga agaagatatc cctgagatct accgtttata caatggccga
    49981 ttgaatgaag aattaaaaag aagctcaaat gaaaatcacg agatcgatca attgctgatg
    50041 cgtaagatcc atgatcgttt tttacaggaa tttcctttta tggaacaagt agaaaacatc
    50101 tcgccaacga tgagctatta caaaatcggc acttattacc atgatcggcc cacggtcggt
    50161 attgatgcaa gtctgccaga aatttttgtt ttgcctaaga tcgatgaaga gtgggagaaa
    50221 tattcccaac cggagtcaac ggactatgac aaaaaaatca atgagctaga cgcaaaggtg
    50281 atcactgctc agacagaaat tgaacgttta gatgaacaaa taaaagaaat caatcgacaa
    50341 atgactgatt tgaacgacaa taaaggattc ttgaatcgta aaaaaatcga ggaagaaatt
    50401 caagaattag agaagaagaa gcaagtacta tctaatgaaa aattaggctg gcttccttat
    50461 attgagacgc ctgaaacaat ccagcagcaa aaagaagcat tgaagcaaga agcaagagca
    50521 gaccagcttc gtgcagccat cgtagaaaaa gaacaaaggc aaatcagacg ctatttcggt
    50581 agcaaagagg gattcggtca agcaatccat gaattcttga tgaattatct tggcaatgag
    50641 aatcctaata atcaatctaa tgaaggaggt tccgagtatg aatgaacacg atgaagcaga
    50701 atggacaaaa aatgaagaac aaacagaaga tcatgaagaa acgaacactt cattggaaga
    50761 acaaacaagt aatcctctgg atgacacaga agaaatccct atgctagagg aaacaaaaat
    50821 acacgaaaaa gaaaaagtaa ctccgacgaa tacgaatact gcagaaaaca cccatgctta
    50881 cgaaataact gaaaatcccg ggtatttaga aggaaaagag caagatcatc aagatatcgt
    50941 cagtttgatt gaaacagcgg aagcagaatt agcggattta cgtatgagaa aagatttgat
    51001 cgaatcagat tttccacaat tattagaatc atatgatcgt tttatattga atgaagaacc
    51061 aatctccacg atcggaaaga caagcctgat cgaatacttc acgtatgaat tactgaaacc
    51121 gttgaatgat attggtctgg aacggtcaaa ttcagcttat gacacatgga aaacaagaca
    51181 tttttcgatc aattatacgt tgaatggaca aaacgaatta gtcttttcct ttgtattacc
    51241 gaccatcgat caacgatacc aagtggaatc gatgagtctc ctaaacgtat caccagagac
    51301 aatggaaatc aatgtccaag atgaccgggt gctttctttg atccgacact ggtcagtgga
    51361 tcgagtattc tctgcagggc agatcacgat attcaatcac aaattgaatc aattattagc
    51421 ccatgcaaga acacttggtt ttaccgttaa tcagacatta ctagacaata cgaagccact
    51481 tcgtttgaat cttcagagcg aatttgaatt gacgaatgaa gtattggatg atatttttat
    51541 cgtggcaatg aaaaatccat cctacgatat ggaaaagatc aacgaaacta cttatcaagt
    51601 acgattagat aaaggacagt ctttaacgat aacaacaaac gaaaaagatc aaacagtctt
    51661 gtcgatctca tctggagact acccacgatc tgtcattgat ttctttatca attacgaatt
    51721 cttggtccca ttaatggtga gaaagtcctg attggataag ttggattacc agatgtcatt
    51781 cagataattc tgttccaaag gacttgcggc agttatccag aataattgtc acaagtcttt
    51841 tctgtatgta ctaaatggac gtgaataact tgctgatgaa ggagggattt cattaggaat
    51901 gtccacaaat aaaatagcac agcttagctt attgtctgct gcttgtgtag caggtaggat
    51961 cgcttttcaa tttattccga atttccagcc aatgactgct atttttttat ttatagtact
    52021 ttacttaagc ttaaaagatg cgttaattgt catgagtctt tctattgcga tcagcagttt
    52081 ttattttggt gttggaccat gggtcatcgg ccaatggatc agctatactg ttgttctgag
    52141 tttgttttca atcgtctgct tgagaaaaac agtgcaaagg aatctatggt taaagggagt
    52201 ctgttttttt ctggcgggca tggtttacgg aataggtatg accgtttttg atacgctgtt
    52261 atatcgtttg cctcaacctt ggatctatta ccttcaaggg gtgtcgtttg atttgatgca
    52321 cagtataggc aatgttgtgt tctttcttgt ttttctgcca gtcgtcaaac gtttttacaa
    52381 tcattcagga ggaaaaaatg aaaaaaataa tttatagttt gcttgcaatg agtgtcagta
    52441 tactcatttt gacaagttgc agtacaacct atacacaatc ggcttccaac caaaaggagg
    52501 aagtaaaaac atcgcaaaaa gcaacaatca cgttacaaga aaatggtcaa aacttttcgg
    52561 aaaaagaagt gttcttcaaa aaaggcgatg atttactgag tattttgaaa cgaaattttg
    52621 aagtcaaaga agataacggc ttcatcactt cgcttgaagg gcactcacag gatgagaaaa
    52681 atcaactcta ttggatgttt actgtggacg ggaaaagtgc tactactggt gccaaagaga
    52741 tcaaattgaa tgatggacaa tcggtcattt tcaatttgtc taaactataa gtttcataaa
    52801 aaactgttaa agggcgaata ttgccataat tcagtgagtt cagttgatga aagaaggaaa
    52861 ataacatgga aaattttaaa aaaagcggaa tgttttccgt aattgctgct ctaggggcta
    52921 atattctagt tgctatcagc aaatttgtcg gctatgcaat cagtggcagt gccgccatgc
    52981 taaacgaaag catccacagt atcgttgatt gcagcaatca gattttgctg ttattcggtg
    53041 ataaacaagc caataaagga cagagcgagt tgcatcaatt tggtgaagga cgagcaaaat
    53101 actttttcag tacaatcgtc gcaatgatgc ttttcttcgg cggtggggca cttggggtga
    53161 tggaagcttt tgaaaagttg acgcatccat cccatgaagt gggtaatccg atcattgtta
    53221 tagcaatact gttatttggt ttggtaatcg aaggaagttc gttacgcgtg gcaatgaaag
    53281 aaatcaaaga attgaatact gaaaaacttt ccacgatgcg ctttttgcgc gaaagtcgac
    53341 acagtgaaat actgattatt tttacggaag acttgtgtgc tgtaatcggt ttggtcttgg
    53401 ctttagcagg aacaatattg acttatgcaa ccgggattgc tgcatttgat gcgatcagcg
    53461 gattgctgat cggtttcttg ctgatgggag ccgccatttt cctagcaaaa gaattttata
    53521 gtctgatcat cggtgaaagc gtgacagcaa gcgatttatc aaaaatcaag ttagcttttg
    53581 aacgtcctga gatcagtcgg ctgatcgata taaaaacagt tcatttaagt ccaacggaga
    53641 ttttagttgc agcaaaagca gatatcgttg gtaacaaaga gaatgaagct tactcggtca
    53701 tcaatgatat tgaaaaaaat atgcgtcagt ctcttcctga caagaagatg tatatataca
    53761 ttgaaacaga taaatatgac ccaaattatt ctcgtaaata aaacgtttat tcatgaattg
    53821 aagcaaaaat gagaaaaata taatcttgtt tttaaataaa acggctacaa tttagcgaat
    53881 ttatgttaca atgagtccgc tgtttatttg ttgtaattaa aggagatatt ttaatgaaca
    53941 aaaagaaaag tgcgccatgg cttcaagctt tgcatgcagt gatgccactt tgtataagct
    54001 atataccagt aggattagct tgcggagtat tgttgcaaaa agttggattt gatcctctct
    54061 tatcaggact gttatcgatt ctggtctttt ccggtggcgc gcagttttta gttgcatcta
    54121 tgcttacgac gcaagcatca tttgcaacga cattattgat ggttttcttt ttagaattac
    54181 gctatacatt attaggagca agtcttgccg gttttatgaa aaaagaaaag cggacgtttt
    54241 tggctgtctt ttctcaatca ctgaatgatg aaaactatgc ggtgaactac ttaaagtttt
    54301 caactgaccc ttcctggaat aaaagaaagg ctttatatgt caattggttc tcaatgactg
    54361 catgggccgg tagcaatatg atcggtaatt ttttcggctc ggtgattcga gtagatgctg
    54421 accttgtcca ttttgctttg acggccatgt tcattttcat gtttatcatg cagatgaaaa
    54481 gcgcactact gatctttaca ggtttattct caggcgtatt aggggtcgta ttcatggtat
    54541 tattccaaaa tactttcgga ttgattgcag caacagtcat tgcttcattt gccggattta
    54601 tgctggagaa ggcattcaaa aaagaaaaag ctaagaaact aagagaccgc ggtaaagatg
    54661 tcaatgagcc gctcttcaac ttcccggaac aggaggccaa tcaccatgac taaactatat
    54721 ttgctacttt tagttgcttg tctgttcatc gtggcatata tcccgcgctt gttcccgatg
    54781 ctttatttta ctcatcgaaa agtgccatcc tggttcagtg actggatgaa atatgtaccg
    54841 gtggcattat ttgcggcgtt agcttttaaa gatgttttca ttactcatga acatctggat
    54901 attgcttgga atatcaaaat agctgcaatg attctagtag caggcgtggc ttacaaaaca
    54961 cgttcgatgg cgttgtcagt tttgacagga cttgcgtctg tctttttgct gtctatgctt
    55021 taaactgttt tattttatta aaaacagaga ttgcgacata agttgttcaa actgatctat
    55081 ccgaactgca tttgcaacag tcaattctgg atgcaagttt attcgtaggg ataaaaaaga
    55141 ttagtgttgg cttatgatgc aagctctttt ttattttagg aattagagag ggatttgtcc
    55201 ttctatgatt ttttgctata atagggaaga tgtttatttt atgaaagaat agttgaggga
    55261 atttaaatga ataaaaaatt gatgcaagga acattttggc taacctttgc taatcttcta
    55321 tgtaaagttt taggggtagt ctatttgatt ccctggctaa gtatgatggg gaacaatcaa
    55381 gatggtatgc ttgctacgac attgtataat gttggctatc ttccttatgg attgttcctg
    55441 atgcttggta cagtcggatt tccaaatgcg attgcaaaaa aagtagctgt agccacaaaa
    55501 gaaggagata acgctgcttg tcggctgatt tttagaagta cgatcaatat catgtttgtc
    55561 atcggtatcg cctctgctgc actgatgtat ttatttgctc ctttactagc cggaatcagt
    55621 ccgattgcta acgttaataa tgggatacta gctatcagaa gtttatgccc atctttgatt
    55681 gctatcccaa ttcttagtgc aatgagagga tatttccaag gaaaaaatga tctgcggcct
    55741 tatggaactt ctttgattat cgaacaggct gtgcgagtga tcgttatctt ggctggtact
    55801 tattacttgc gcgtattgac tgacggaacc atattagaag ctgtattgat cagtacagtc
    55861 gcttctttct tcggtgggtt agctgcgatt atccatatgt atatcgtcgg acgcagaaaa
    55921 gacttcttcg aacttaaaga ttttttgatt tccagccgtt atttcgaaag agaaaaccga
    55981 tctgcctctg tctctatcat tcgggaaaca ctaccgttta tttttgtcgg ctcagtcatt
    56041 actatcgttc aaatgatcga ccaagtaacg atgaaaccac tgcttcactt tttccgtcca
    56101 gagatcgcag atcagcaact ggaattctta ttcagccgtg cttctgtcaa tccaaataaa
    56161 ttgacattga tcctgatctc catggtagga acagtagcta taagcagctt gccaatatta
    56221 agcacgatga agaaaaaaga tcggatacaa atcgaaaaaa cagtaggaga tagtttttcg
    56281 attgcgttat tgattcttct tccttcattg actggaatgt ctttattagc tggaccacta
    56341 tacacattgt tttttggcta tgatcctgaa agtgtcggat atttccaaat ggctttgcta
    56401 gcttctttgt ttttctcttt attcacgatc ctatctacga tgcttcaatc tttgaatcac
    56461 catcgttttg cgatccgatt aactgtagaa gcaattatcc tgaaagtcat cttccaagta
    56521 atcggattag gattagttgg cggatacggg atgagcttat caaatggctt agcattcggt
    56581 attgtctttg ttcgcggcta tcactttatg tgcaaagaat accgaatagc acctttagca
    56641 aagatcagca attttttctt aaaaactttc cgctccaccc tgattatgct tgcagtatgt
    56701 tttgccgttt tctttttgct gaatcagcga ttgtcaatgg aatcaaaaag ctatgcaatg
    56761 atttattgtg tggctgtagg aagtattggc ggcttagtat ttttattttc tcaattcgga
    56821 aaaaatgggt ttcgaatgtt gaaaaatgtt aaacatcata gcagaagcaa agaataggtt
    56881 aactaatcgt tttttgctgt cacttgaaaa acggcaactc gtatgattac gcttgtcgtt
    56941 tttctatttt ccaattttag tttcatatct aatcttactt atgatatagt tataaggtct
    57001 ggaaaaattc tttgaaacga ggaaattaaa cacatgaaac ttgcagtagt tacagatagt
    57061 tcggcatatc tgccggaacg tatcaagaac catcccgact tattcgttat tccaatccct
    57121 ttgattatgg atgggaaaat ttataacgaa ggaatcgata tcgaagcgga tgaatattat
    57181 ggacttttaa aaaacagtaa agattttcct actacttcac aacctgtcgt aggggaagtt
    57241 ttgggtttat atgaggaatt gaaagagaaa gggtatgaca cgattttaag tatccatctt
    57301 tcttcaggga tttctggctt tgtcaacaca ttatttgcga tgaaagatga catcagcgga
    57361 gtaacggtca ttccttatga ctctaagatc actagtatgc cgatgggaca catggtagaa
    57421 gctgccttag acttaaatga tgaaggtcag tcccttgatg aaatacttgc acatatcgat
    57481 cgaatccgag ataataccta tgcttatctg attgtagatg atttgaacaa tttagtacga
    57541 ggaggacgtt tgacaaatgg tgcagcgctg attggcagct tattaaaaat caaaccgatc
    57601 ctgacatttt ctgaagggaa aattgtttta ttcgaaaaaa tccgttcaag taaaaaagca
    57661 tttgctcgag ctgaagaaat tattggtaga agaaataacg aaatacaacc gccagtcaaa
    57721 ctttacgtga tacatgcaaa taatttagaa gtagcgattg cggagaaaga gaaattgcag
    57781 aaaaaatatc caaatgcaga aatcgaaatt ggtcatttcg gaccagtcat tggtacacat
    57841 ttaggtgaaa aagccatcgg cattgccatt tcagcgcaat aattcctttt attcaaaaaa
    57901 cataccaaaa atat
//
LOCUS       DAIGQM010000010        57575 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.010, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000010 DAIGQM010000000
VERSION     DAIGQM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.010"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            591..1280
                     /locus_tag="NOA48_000551"
     CDS             591..1280
                     /locus_tag="NOA48_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0788842.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="NOA48_000552"
     CDS             1267..2475
                     /locus_tag="NOA48_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0788843.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="NOA48_000553"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="NOA48_000553"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCI0788844.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOA48_000554"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="NOA48_000554"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCI0788845.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="NOA48_000555"
     CDS             complement(6578..7273)
                     /locus_tag="NOA48_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCI0788846.1"
                     /translation="MEPEQLRAIVKENNGLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="NOA48_000556"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="NOA48_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCI0788847.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="NOA48_000557"
     CDS             complement(8472..8663)
                     /locus_tag="NOA48_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCI0788848.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="NOA48_000558"
     CDS             complement(8684..9574)
                     /locus_tag="NOA48_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCI0788849.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="NOA48_000559"
     CDS             complement(9561..10328)
                     /locus_tag="NOA48_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0788850.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="NOA48_000560"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="NOA48_000560"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCI0788851.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="NOA48_000561"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="NOA48_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCI0788852.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="NOA48_000562"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="NOA48_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCI0788853.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="NOA48_000563"
     CDS             14899..15282
                     /locus_tag="NOA48_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788854.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="NOA48_000564"
     CDS             complement(15450..16208)
                     /locus_tag="NOA48_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCI0788855.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="NOA48_000565"
     CDS             complement(16226..17044)
                     /locus_tag="NOA48_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0788856.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="NOA48_000566"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="NOA48_000566"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCI0788857.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="NOA48_000567"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="NOA48_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCI0788858.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="NOA48_000568"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="NOA48_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCI0788859.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="NOA48_000569"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="NOA48_000569"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCI0788860.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="NOA48_000570"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="NOA48_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCI0788861.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="NOA48_000571"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="NOA48_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCI0788862.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="NOA48_000572"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="NOA48_000572"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCI0788863.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="NOA48_000573"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="NOA48_000573"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCI0788864.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="NOA48_000574"
     CDS             27086..27385
                     /locus_tag="NOA48_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCI0788865.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="NOA48_000575"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="NOA48_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0788866.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="NOA48_000576"
     CDS             27973..28209
                     /locus_tag="NOA48_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCI0788867.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="NOA48_000577"
     CDS             28352..30325
                     /locus_tag="NOA48_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCI0788868.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="NOA48_000578"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="NOA48_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCI0788869.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="NOA48_000579"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="NOA48_000579"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCI0788870.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="NOA48_000580"
     CDS             33204..34496
                     /locus_tag="NOA48_000580"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCI0788871.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35232..36095
                     /locus_tag="NOA48_000581"
     CDS             35232..36095
                     /locus_tag="NOA48_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0788872.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36224..37846)
                     /locus_tag="NOA48_000582"
     CDS             complement(36224..37846)
                     /locus_tag="NOA48_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0788873.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38095..38616
                     /locus_tag="NOA48_000583"
     CDS             38095..38616
                     /locus_tag="NOA48_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0788874.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38802..40531)
                     /gene="spxB"
                     /locus_tag="NOA48_000584"
                     /pseudo
     CDS             complement(38802..40531)
                     /gene="spxB"
                     /locus_tag="NOA48_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
     gene            40696..41514
                     /locus_tag="NOA48_000585"
     CDS             40696..41514
                     /locus_tag="NOA48_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCI0788875.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41617..41814)
                     /locus_tag="NOA48_000586"
     CDS             complement(41617..41814)
                     /locus_tag="NOA48_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788876.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41983..42561
                     /locus_tag="NOA48_000587"
     CDS             41983..42561
                     /locus_tag="NOA48_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0788877.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42656..42793
                     /locus_tag="NOA48_000588"
     CDS             42656..42793
                     /locus_tag="NOA48_000588"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788878.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43606..44109)
                     /locus_tag="NOA48_000589"
     CDS             complement(43606..44109)
                     /locus_tag="NOA48_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0788879.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44468..45493
                     /locus_tag="NOA48_000590"
     CDS             44468..45493
                     /locus_tag="NOA48_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0788880.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45840..46718
                     /locus_tag="NOA48_000591"
     CDS             45840..46718
                     /locus_tag="NOA48_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCI0788881.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47194..47310
                     /locus_tag="NOA48_000592"
     CDS             47194..47310
                     /locus_tag="NOA48_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0788882.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48238..48576
                     /locus_tag="NOA48_000593"
     CDS             48238..48576
                     /locus_tag="NOA48_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788883.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48670..48900
                     /locus_tag="NOA48_000594"
     CDS             48670..48900
                     /locus_tag="NOA48_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788884.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49300..49671
                     /locus_tag="NOA48_000595"
     CDS             49300..49671
                     /locus_tag="NOA48_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI0788885.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49945..50637)
                     /locus_tag="NOA48_000596"
     CDS             complement(49945..50637)
                     /locus_tag="NOA48_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0788886.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50640..51425)
                     /locus_tag="NOA48_000597"
     CDS             complement(50640..51425)
                     /locus_tag="NOA48_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0788887.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51662..53062
                     /gene="lacG"
                     /locus_tag="NOA48_000598"
     CDS             51662..53062
                     /gene="lacG"
                     /locus_tag="NOA48_000598"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0788888.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53087..53404
                     /locus_tag="NOA48_000599"
     CDS             53087..53404
                     /locus_tag="NOA48_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0788889.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53417..55090
                     /locus_tag="NOA48_000600"
     CDS             53417..55090
                     /locus_tag="NOA48_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI0788890.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55104..56735
                     /locus_tag="NOA48_000601"
     CDS             55104..56735
                     /locus_tag="NOA48_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCI0788891.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
BASE COUNT        17720 a        10594 c        11446 g        17815 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac cattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaacaaa cggtgttcaa aagcttgcat ctacggcact aagcccaatc
    34681 agatgaaaaa tatggagtgc tatttttatc tgattgttct tactgcttga tgcagagcag
    34741 ctttttcaca acctctccac taaacggtgt tctcctgcca actcctcggt cacaagtcac
    34801 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagctaaa
    34861 cggcaggctc acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
    34921 aaaaaacggc aaaatatgag gaactatttt ttccgttttt ttctctaata ctcaggtcaa
    34981 aacgctgatt tcacaacctc tgattcacgg tgttccagaa gtagcttcta cggaaataag
    35041 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    35101 tgaccacttc tgtcacaacc tattattttg attagaactt gcgaaaataa accggttaaa
    35161 gtgtgtctag cgcaagagat ttgctataat agacgataag ggtaaaatgt aacgagaagg
    35221 ggttgaaaaa tgtgtatcaa attgtaacag attcttgttg tgatctgcca taccatgtat
    35281 tagcaaaaga aaaagttgat tttttatcaa tgaatctcca attgaatgat caagagttag
    35341 tagatgacct cggaaagaca ttcaattatg accgctacat gaatcagctg aaaaatggtg
    35401 cgatgcctac gacatcacaa atcaatgttg gccgatattt agaatttttc cgttcttatg
    35461 cggaaaaaca gattcctgtt ttatatgtgg ctttttccag tggattaagc ggctcttaca
    35521 gtagtgcgct tcaagcggtt gaattgctga aggaagaata tgaagaccct gagatctatg
    35581 tttttgatac aaaagctgca agtattgggg aagggctttt agtattggaa gctgtaagat
    35641 tgaaaaaaga aggtaaaagc atcgaagaaa ccctagagtg gctggaaagt aattatttga
    35701 aagtccattc atgggtaaca gtagacgatc tgaaatatct agaacgaggc ggtaggattt
    35761 ccaaagcaag tgctactctt ggcagtctat tgagtgtaaa gcctattatt acggtggata
    35821 aagaaggaag gctgacgaat gttgacaaag ttcgaggaag aaacaagtcg atccagacaa
    35881 tcgtcaatga gacggtaaaa acaatcgttg caccacttga tcaaatcgtt tatgtggctt
    35941 acgctgggga tctagagagc gcggagaagg caaaacggct tttggaagag cagataaaga
    36001 tgaaagatgt gaagctttat cccttaggac caacgatcgc cagtcacaca ggctatggct
    36061 gtatcgcgat tttttcgatg ggaatcagtc gataaaagca gtaactcatt ctgtaaaaaa
    36121 gcccagaaat tgattgtaac aaaaacagcg actcttaaaa gatagatgag catcctatct
    36181 cttagaggtc gctgtttttt tattttttaa gctaaatagg ccattatgcc cataactcgt
    36241 tcaattgttt ttgaatatct gcattttcca aaaattcatc atatgtcgta tcagctcgat
    36301 cgatcacacc tttatccgaa acggcaatga tgcggtttgc caatgtttgg ataaattgat
    36361 ggtcatgtga cgcaaataag attgagccag taaatgccat caagccgtca ttcaatgctg
    36421 tgattgattc taagtctaaa tggttcgttg gatcatctaa tacaagtacg ttagctttcg
    36481 aaagcatcat ttttgaaagc atgcaacgga ctttctctcc accagataaa acattcactg
    36541 gtttcaatac ttcttcacca gaaaacaaca ttcttcctaa gaagcttctt aagaaggtgt
    36601 tatcatcttc ttctttactt gcatattgac gcaaccagtc taaaatcgtt agatcagtat
    36661 cgaattcttt cgttgtatcc tttggtaaat aagaattact tgttgtcaca ccccaacgta
    36721 ctgttccagt atctggcgta atttcaccca tgataacttt gaatagcgtt gttgttgtta
    36781 tatcattttc tgcgacgaaa gcgaccttgt cttctttgct caaattaaaa gatatatcat
    36841 ctaaaatttt ctttccatca atcgttacac ttacattttc tacctgcaat aagtcgtttc
    36901 caatctcacg ttcaggtttg aatccaacga atggataacg tctagaagaa ggttggatat
    36961 cgtctaaagt aattttttca agcatttttt tacgtgaagt tgcttgtttt gattttgatg
    37021 cattcgcact aaagcgggca ataaattctt ggagttcttt gatttgttct tcttttttgg
    37081 catttgcgtt tgcttgaagt ttagccgcta gttgactaga ttccaaccaa aaatcataat
    37141 ttcctacata aagtttgatt ttaccaaaat ctagatccgc catatgtgta catactttgt
    37201 tcaaaaagtg acggtcatgg gatacaacga tcacagtatt ttcaaaattg atcaaaaatt
    37261 cttccagcca attgatcgat tggatatcca gaccgtttgt tggttcgtct agcaaaagaa
    37321 catcaggttt accaaatagt gtttgtgcta ataacacttt taccttttgt ccaccagtta
    37381 attcactcat ttgctgatgg tgcaattctt cagggatgtt cagaccttgc agtaaaacag
    37441 ctgcttctgg ttcagcttcc catccattaa gctcagcaaa ttctccttct aattcagctg
    37501 ctcgaatacc atcttcgtca gtgaaatcct ctttcatgta aatcgcatct ttttctttca
    37561 gcacttcata cagacgcttg tgtcccatga tgactgtttc aagtacagta tagtcttcat
    37621 agtcgtaatg gttctgtttc aatacggcca tccgttcatc tggtcccata gtaacggaac
    37681 ctgtggaagg ctgcagatcc cctgataaca ctttaaggaa cgttgattta cctgcaccat
    37741 ttgcaccaat caagccatag cagtttccgg gggtaaattt aatattcaca tcatcaaata
    37801 gtttgcggtc tgaaaagtgc aaactcacat catttacagt aatcaatttt tttcctcact
    37861 tttatcatta ttagttttga caagtcttat agaattatat aggggaaagg taaaagattc
    37921 aaggcaatcg aacattcttt gtgtttcacg tgaaacagaa tgaaaaaaat aaaaataaaa
    37981 gcggagcgaa aatagctact ataggattta ttagtttgca acagcataat ttttgacgtt
    38041 atttataaga gggagtacta taaaactgta aaagaaatga aagaaggatt gaaaatggat
    38101 gaaaaaagaa ccatcgactg gggctcattg attttgggaa ttttatttgt acttgtctca
    38161 ttgttatcat ttcaagaccc tgtcggaaat ttagttgcaa ttgtagtagt ctttgcgatt
    38221 tttgccttta ttaaagggat atttgaactg tttgtacgga acagattaaa agagctaaca
    38281 ggatataaag gaaagatgcc cttaataatc gggatcatcg atattctagt tggcgtcttt
    38341 ttcttattca atattggtgc aggagtcgca gcattgcctt ttgtttttgc agtatggttt
    38401 attgctgatt cagttttagc gttatttact gctgacttgg caagaggagt aagtgaagga
    38461 tattattggt ttacgatcat cgtcaatatt ttaggaattt tattaggaat tttcttattg
    38521 tttaatccaa tttcttctgc gttgacatta agctttttag ttggattcta ttttatgtta
    38581 tttggtatca cacatatcgt ctatgcattt agataagtaa aatcaaacaa ataaaaaagc
    38641 cggcttccga ttacagtttt actgttgtaa ttggaagccg gcttttttat catggacaaa
    38701 tatgcacgag gtgattttta ggtgtcgaga caaatttatg caaaaatgtg agaagctata
    38761 tacacaaatt ttatcttaat actcgaagca tagcgcagtt gtcacaacct cttttcatat
    38821 aattcattca atactggcaa atcatggact tcatattttt ctttgaatgc ttggatttct
    38881 tcttcagaat attttcttgg atctaaatgc agatcttcta ctggcaatgg gtgcttgtta
    38941 ttgatcttca catcgattac tacaggacga tctgattttg cagctgcatc aaaggcaaat
    39001 cgaagttgcg agtattctgt gactgtaaag ctatttgccc cgagcgcttc tccaacttta
    39061 ccgaaatctg catcttctaa aaatacacca aatttctttt gttccgtatc ttcttgttct
    39121 gcttcgatga aaccaaaaga atcattcgaa aagacaacat taataattgg aagctgatat
    39181 ttgacttgtg taatgatatc ttgcatgacc atagcaaacc cgccatcacc acttaaggta
    39241 aatacttgtt tttctgggta gcttagttgt gcggcaattc ctcctggcac accattaccc
    39301 atagttgcga accatccaga tgtcgtatgt ttttgtttac cgttcatatt caataaacga
    39361 atagaatgga tagtcgtgtt accgacatct gtgacgaaaa tcgcatcgtc ttcagcaata
    39421 cgattgattt ctttatagac agcctctgga cgaatcggtt cttcctctcg atcttcaaaa
    39481 gatttcaacc aatttaccca tttttcttta ttttcttgat ttgctaggta ccagctatca
    39541 gcagggcgag catcccctaa ctcgacaagt ctttgcaaag ctgtgtttgc atcaccgagg
    39601 atcgacaaag atgtttcatg gcgtcgtcca aattttgacg catcgatatc gatttggata
    39661 aattcagcag ttggattaaa aaatgcacgt ccaaatggga agtcgctacc gacaaataag
    39721 atcagatcgg cttctgccaa tgcttcattt ccgggtttag tagcgacacg tccagcaaaa
    39781 ccaagaaagt tttcataatc atcaggaata attccttttg ctagaacgga agcgacaaca
    39841 ggaactgaaa aatgttctga gaattctttg atttgcggaa atccgtttcg cgttccttga
    39901 ccaacataaa gaactggttt ttttgctttt tcaagataag gcaaagcagc tagcaaatct
    39961 ttttcttctg gtaatatcac acttgttttg tgagtgtgag cggtggagaa aggttgttcg
    40021 tcaatttctt caaaaccaag atcaacaggg atagtcacga tagccacgcc tttatgctca
    40081 taggcggctt taatggcttc atctactaca tgcggaagac tttgtggtgt catgactgta
    40141 cgattgtata cgctaacatc tgcgaaaata ggattttcat tagttcctgg aaagagttat
    40201 agttcatgga tgtagaagca acttgtccta agaacgctac tagaggcaca tggtccatct
    40261 gtgcatcata caaaccattg atcaaatgtg tcgcaccagg tcctgcagag ccgaagacag
    40321 cgccgacttt ccccgttaat tttgcatctg cagcggctgc gagtgcgccg acttcttcat
    40381 gacgaacttg aatgtagttg atttcggttt tttcttgata tagcgcatcc ataattgaat
    40441 tgaaagatcc tccgggaatg ccgtaaatat ggtcgatacc ccagctttca agaactttta
    40501 ccattgcgat tcctgcattg atttttgaca tggtgtttca ctcctttagc aatgatgata
    40561 cataaatttt ttgtatctag agtatagaac tttttatcga aaatcccaac taattcgtct
    40621 tttcacaaaa atgtagtcat gtttttggga atatgctaga gtagtacata gatagattca
    40681 agagagggga atggcatggt tgaatggcta ttgagacttg aaccttggca gcaagcactt
    40741 gctgggacag cttttactta ttttatgaca gctcttggtg ccgggttggt ttttttcttt
    40801 aaagaaatca aaaaagaagt gctaaacttg atgttaggat ttgcttctgg tgtcatgatt
    40861 gctgcaagtt tttggtcttt gttagatccg gctattacaa aagcagaaga aaatggagat
    40921 attgcttggc tagttgtaag tattgggttt ggtttaggcg gtgtgttttt atatatggca
    40981 gataaaacac tgccccatat gcattttgga ccacaacatg aagcagaagg attgcctacc
    41041 catttaaaac ggacgatctt gcttgttttt tctattacat tgcataacat tcctgaaggt
    41101 ttagccgtgg gggtagcatt cggtgcagca gcaactgcgg ataatccgac agccgctata
    41161 ttagccgctg tttcggtggc gctaggtatt ggtatccaaa acttcccaga aggagcagct
    41221 gtatcaatcc cgttgcgaca agaaggtctg agtcgtaaaa aggcctttgt ttacggacaa
    41281 gcttctggaa tcgttgaacc aattgctgga gtgattggag cgctactagt aacgaaagtg
    41341 gagctgctgc ttccttatgc acttgctttt gccgcaggag caatgattta tgtcgtggtg
    41401 gaagaattga tccctgaagc acagcagaca ttgtccagca aacgtcattt tgcagttttt
    41461 ggcgtcatga gtggatttat cattatgatg attttggatg tggcattagg ataaataaaa
    41521 aaaatatata tgatatatca aatagggccg cgaacttata tcgcgaccct atttttttag
    41581 taagttatat cataatgaag tgaatggtat catacattaa taatagtttt ttctatgtgt
    41641 atttcctttg atccagcgaa caagccagat gataagtgcg attgggatta gaactttgac
    41701 cgcaaaccat aaaagcccgc ttaggacact gacaaaaaga ctgatgacga agctagctgc
    41761 aattagcact aaaagaacca tgaagatatt taagaacata tttttttgac gcatacaaaa
    41821 ccctcctctt gttcattctt tactatagaa aaagtataac agggattgtt taaaaacacc
    41881 tccaactgaa gactgatttt tacttcatct acttaaatga tcaaacaatt gctttttctc
    41941 tggtttatca tctaaaatag agcggaaaag gaggagaata tcatgcctaa aaatcgtctt
    42001 gaagcattta cagatgctgt aatcgcgatt atcatgacta ttttagtttt agaacttcat
    42061 gaacctaacg gagacacgtg ggaggcgctc gctgcattag gttaccgatt ttttatctat
    42121 attgtcagtt ttatcatttt agcgatttat tggaacaatc atcatcattt atttcaagtt
    42181 gtacataaga taaatggacg ggtcttatgg gcgaacagtt tctttgtttt tgcgctttcg
    42241 ctttttccgt ttgcaacttc atggatcagt gagtacatca atagcctggc tccagaaatg
    42301 acttatggtt ttgttacctt gaccgctaat attgcgtatt atatcttggc aaaagaactt
    42361 gtcaaagcaa ataaaggcca cgagaaagca ttgaaggcga tgttgaataa ttacaagaaa
    42421 tcgtatctat cgattggttt gaatgtgtta ggaattgtct tagggtattt agtagcgcca
    42481 gtagccgtgc tgatcgcaaa catcgtgatt ctagctgctt ggatcatccc aagtcgtacc
    42541 atcgaatcac aatatcggta aaatgatccg tgtttaaaat ttaagagaaa aatatagaaa
    42601 aaataaataa acgatcaaat atccgagtga tactagtatt caaagaggga tgcagatgga
    42661 tcaaaaaaga attcatgtag gactgattac tagttttgtc acgatgctta tttatttgga
    42721 tcaaggtcat ttgacttgga cagtagttgg tgtcgtagga tttttgacat tattcacagc
    42781 aataaaaaaa taaacatctt tatgtaatct gatgttctat ctatttaaga aaagcatgtt
    42841 tacagcagta tgattctgtt gtaaacgtgt ttttatttgt ggaaaattta atttttagaa
    42901 aagtgtatcg aaaaatagat agttagtttt tccacagtgg ataacttcgt aagagataaa
    42961 aataaaaaat tagtcaaaga agggcgtata gatttctttt gataggagat atacaacaga
    43021 aatgaataaa tattaacgtg ttttcaaaca gtataaaacg gtgtggtttt tggaataaaa
    43081 aaataacata tctcatttta cgcttttgtt attttatact taaaaaataa cgacacagaa
    43141 aataccgtgt ctcagatttc tctactactt ctaaaaacta ctgttttttt cctttgaaat
    43201 gccttcaaaa agtaggatca ggcagaatat actggcagaa tcaaggagaa gggagcctaa
    43261 ataaggagaa aaaccataga aaatataaag taattactta taaaacaagc tttttataga
    43321 aaaataatat acctgagtag ggtataaatt aagacggaat tcctttctag attgagatat
    43381 tgactaggaa gaatgttaag attttaagcc tttaagctaa aaaaaaaccc tttttgttaa
    43441 ataaggggaa tatagcctgt cagtttcaaa ctgcaagtcg tcctgctgca ataatatagt
    43501 agattagaga tgaaaataga tttttttaaa ccaatgactg aataaaaaga ccgtcataga
    43561 tacacattgg aatgtgtcta ttacggtctt tttttacgaa cgattttatt gaagacggac
    43621 agttcgggtc aaaaataaaa aagctacgat cagaaataag aataaaatgt atcccaaaat
    43681 aatggctaga cggtctaact tatttgtcga tagatgtttg tttagaagtt gataggccca
    43741 taaacctatc agtcctcctg ttgtattagt tatcaaatca gtgatgtccg ctacgccaat
    43801 accgaatagg aattgaatca attctgccaa gaagcttaca aggaaaataa tccctaattt
    43861 tttagaaaaa gaaagtctct tgaaattgac attcaaaagc accccaaaag gaaaaaagac
    43921 aatcaagtta taagtggtct cacgtaatac cgtcgtattt tcaaaagaaa aagtagaaaa
    43981 agggacgaga ttgacattgc tgtaagaata agtgagaaat tgtggaagat taaatgatag
    44041 cttgaataaa atcaaccata atagaaagaa taaataaatc cctaataaaa attttgatac
    44101 ataccgcata gacatctcct ccatttaaaa agtataccat cgaaaaccgc tgaaaaatca
    44161 taaaaaagta tgaagtttaa ggaccaacgt agttatcgta cgaaaattag aagctttttt
    44221 ttgttgggaa tccggtttct ttaacaaagc taagatagcg agttgcttgg aaaagttgct
    44281 atcttttttc tgtcaaaacg actcggaatg ttcgtttttt gttctaattt ctccaagttg
    44341 tttacttttt gatactaagt ttatgaaaaa tcaagaaata gttgttatac taggtaatgc
    44401 tgacaaacgg gattggcatt tcatcttggt tcagcttttt ttccaattac taggaaggag
    44461 ggatagattg ttcaagactt attttcgttt caataaaata caagataatc cttttcgtat
    44521 catgaatctg atgctactta tctttattgt attatggtta ggttacataa atcatgattt
    44581 tttgatttca agtttttcat cattagggat ctttactttt ttctattatc aaaacatacc
    44641 gatgaaatat ttgctgaaac gtatgtttct gatcggttgc ggactgttgg ttgctttcgt
    44701 tttggggatc ttatcgactt atgttttatg gcttgaacca tttgccgtag ctttggttgc
    44761 tttttccagc agattcgtgt tgcgattatt ccatatttct aaaccaggtg gcttgttttt
    44821 tgcgatgctt tctgccatgg gaacgagcat gcagctgcca atcgctcaat taccgatcgt
    44881 ctcactttat ttttttatgg gtgtcgtttt tgccctgatt gcggcagtga ttacaaaatt
    44941 actggattca cggcctgagc agacaattga aaaagcaact ttaaaagaaa gatttcacga
    45001 agagccttta gtgatcattg attctgtttt ctacagcgct gccttatttc tttccgttta
    45061 tgtcagtcac ggcttgaatc tgcataatcc ttattggttg accttgtcat gtgcatcgat
    45121 tttgctagca gaaaacttgg atgcgatgaa gcatcgacaa gtccaatatc tgattggatc
    45181 gatgggtggg ttatgtgtgt cggcattctt gtcatttgtg ccgtttacgc agttgcagac
    45241 catttttctg atcacttttc tatatggaat cgcacaattt ctagttgcta gaaattatgc
    45301 agttgctaat atttttctta atccgatggc gttgatgcta tctacactta ttcgtggagc
    45361 atacttgatt tctttgatcg aatatcgttt tttagggatc gtcataggaa gtttcatcgg
    45421 tttaggtgtt gcgtgggtaa tgacggttgg tttgcaacat tatttaacgg ttgttcgtca
    45481 aaaattagaa tagaaggaca aatatatgtg ccaaaagagg ttatgacaag atttttgtca
    45541 caacctctaa ttcaaggtgt tcaaaagcca gattctcagc attaagtcaa attcacacaa
    45601 aaatgtggaa aggaactttc aaaaaaattt tatatttatt ctatcaaaaa attttatatt
    45661 tattctatca aaaaattttg tttatgatgg taactgaata aactttcctg agatggtcaa
    45721 tgctttcctt gaaagtctta cagatattct ttcttcatag aaagtttaag ttttatagtt
    45781 agtgtacaat aaaagtatgt ttataccata tggtgtccgg ataatcagtc atttaaacaa
    45841 tgaggttcaa agatatgaaa aggggaaatt tgatgaagaa aataagcaat gaaatccaaa
    45901 ttctggcaga aactttaact cttcccaaag tcgttataga gcaaatgatt gtacaagcaa
    45961 aaaacatcct tgatgaggtg tttgagcaat atagtcatga actaatggat cctaataaag
    46021 caaaggcgac tgcaaagaaa atagacaaag tctatgaaga ggaacctttt gcagcattag
    46081 ctatttatct atatgcagct tctcaaagtt ggaaaaaaat ttatcaacca ttgaagattc
    46141 caagaactat ctatttggca acaatgaatg cttttactag atttattcat gaacatttcc
    46201 aagtaacagg aagctatcgc tttgaccgtg gtttttggat ttggcattac actagtggct
    46261 tgatctttcg gattggtgaa ttggagtacg aaatgacata ttttccgaaa gggtacacgg
    46321 atctaagatt agaaggaaag cagtgccttt ctcttcatat tccttccgat gcagatttat
    46381 ctcagaataa gataagagat agttacgaaa gtgccattcg tttttttgaa ctttattttc
    46441 ctgattacca ttaccaagtg atgtacacag atacttggtt actatcaccc aatcttacta
    46501 aatggttgaa aaaagagtca aaaatctgtc tttttgcagc cgattatcga ttattatcag
    46561 ttgatgaaca ggacgatagt ggagtccctt ggatctttgg acgagtagat gcccaaatac
    46621 atgattatcc agaaagtacg agtttacagc gacaagcaaa agagcaattg cttgcaggcg
    46681 agcacattgg ctctggctta ggtattctta cttcataagt ttagtacttc gaaatagttt
    46741 aaaagagcgt gagacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    46801 ggcggaagca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca
    46861 attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt
    46921 agtgttctat cgaacacaca gtacgttcaa taggtaaact agctataaca atagatatta
    46981 aagttaacgg acaagagggc cttttttagg tagctaaaac gtaataatga aaatttattt
    47041 ccagagatag gagtcaatca gctagtctga tcgactgttt taacaagttg actttcattt
    47101 taacttttga taccatttaa aacacaaatc gtaattgttt cgatttgtgt tttttagcat
    47161 gactacaatc aaagaagaaa gtgggtcgtc catatggaaa aaacagatat ctcaagtgca
    47221 taccgccgct tgaaaagccc aaatatcaaa acacgaaaac gtgcgctgaa gatcatcaaa
    47281 gatgtgaaac ggaatagtgg gaaaaggtaa gaagaaggaa acttaattaa aaaaatagcc
    47341 gaaaaacgtt tttcggctat tttcaataat cggtttttgt gtaaggtttc cgaaagaact
    47401 gctgttgatt ttccattttt aacatatgat aaattggtag aatctttctt ttcaaattga
    47461 taccattccc taattccagt tatatagtta actacagaac cacaaagcac gtacgtttat
    47521 aaaagtatta tctgtagtta tttttcaatt ccctttcaac ctcttatttt gaccagtagt
    47581 attgatcact ttacctttta acacctttgt tcgtttttga aacattttta gtcaagaatg
    47641 gaaacgtaac tacataatca aaggttttgc gaaatatttc atgaaatatt tcatgtagaa
    47701 gcgagcaata cggttgcaaa taaccattat cgtttaataa gcagttacga aagctcccaa
    47761 tatctctaac gttcagctca ctccatttct tttcttcaaa aaaatcagtg attcgtatct
    47821 ctttctattt gtcgaaaaag ttaactttaa aaagtaacgc cgaaaaaata tgcaaaaaaa
    47881 taaaaaagca gttactattg ctagaataac atcaaggaat aataagtttt ggttttcaga
    47941 taatagtcga taagttgtgt attggaattt tagatacagt aataaagtat ttttcatgaa
    48001 attttgtgag aatcactatt acaagtatct ttaataaaat taatggttaa ggaggaactt
    48061 aaagtagaat gtaaatgaat agttgtagtc agtcgattgt gatactagac tcaaagttgc
    48121 aggaataagt ttttcaattt gtgattggaa gataaaaaat gaaaaagaag ggcttttttt
    48181 tatactttgt tgattgtagt gtttattttc cctctgttta gccaagtaac attttctatg
    48241 actcaaccag tttcaagtga ggaacatgat aacctttttc gtgctacaga agagtttaag
    48301 aaatatcagg aaaatattgt tccggagact ccattagcta gtgagccaat tactgatatt
    48361 gatggaaacc aaataggatg gtatatacag tacgaagtta tggtggtaaa taatgactca
    48421 atagtaaaaa atacagtagg cttagagcta acaccgattg aaaaggtgag ttcattgtta
    48481 acgtatattt atactgatga aagtgacgag actgagatca ttttaacgga ttactcaaaa
    48541 attgctactg ataaaaagta tatattgtgg atgtagacac tagtgaaata ctttatgata
    48601 tagaaattga tgaaaattta ctagatgtag cacaagaaat cgatcatcaa aagcaggaag
    48661 ctattcgata tgctggtaga aaagggaaaa gaaaatattt attacgtgaa tgtagcaaaa
    48721 gttagagaag atgaaaatga gtggaaagaa ttcaagagtc gctactcaat taactcgact
    48781 ccgacattta cagtttacag agaaggatcg atagaaaaaa ctgttttttg gactaaagaa
    48841 agtggaatgt ctttagctga agtagaagag tttttggatt atgttagtat gcaacagtaa
    48901 gggagttctt attatgaaaa attttgacac atattatgtt attgtttttt cgatatcttt
    48961 gctgttaata ttactaactt taatgcagta taaagagtat ccagagtatt ttattttaac
    49021 ttttgtatat ttagtaagta gctacacact tctatataaa ttcagaagtt cttctagagt
    49081 ttctaaagtt tgtttcttaa ttagcttatt gattctataa tatttttgat ttatatagga
    49141 aattaaaaat attatagaat caacactcag agaacgggtt ggtttttaat agatttaata
    49201 agtactgata atgaaatttc tcctggttgg gaaaacgaag ttggttaccc tgtagaagaa
    49261 ttttttcaag attactttgc ggagtatgcc gataggataa tgagagatta cgtaacagat
    49321 aaaactcaag aagtcatcaa tcaatcccag tcattaaatg aattatctga taaggcgaaa
    49381 gaagaagcag ttgccattat ttcttcaggg attagtgact atattgatat gagtggtgaa
    49441 atcaattatg gcgataaaga caaaattgta cgcatgataa aagcttttat caaaactttt
    49501 gatgtgaagg cagatcttaa gtttaatgat acttacctag taggaaaatt aattaatatc
    49561 cttgggacag agaaagatac ggaaacgttt atttcctctt tgtctatgtt gtttacagat
    49621 aagcattttt caactcagct tggtggagag gaactagtgg aaatctttta accattacgc
    49681 ccagcattaa taaaagtata tcaaaaaagt actcctgatg atttttaaga ttggtttgag
    49741 aaataatgtg aaaacactat ttttaatgtt aattatagat agagatgaac gcgtcatatg
    49801 gttaaaagaa tgaaaaagtc aaagatacac tgctatattt cactaaggat atagcagtgt
    49861 atctttcatg tcgtttcact ggcagttttt tataaaagga ggtgtgcatt tcagttgctt
    49921 ttctttggta gttagttgaa tcgtttaaga attaacggat gtggcagaca ggtgctctgt
    49981 ccaaaaacca gtaaaatctt tgatggttcc atctttattt agctgtgcct gttcaaatac
    50041 tgttttgttt ttaccgaatg gatcaattgc aataattgtt ccgatccccg cacgtttggc
    50101 agcaagtaat cctgagtaag catcttcgat aacaagacaa tcagccggag ctaagctcag
    50161 tttgtctgcc gctttaagaa aaatatccgg ttgcggtttc ccagggaaag agccgtcgtc
    50221 atagacaatc ttgtcccagt caaaccagcg ggctaaatcg aaaatatcaa aataaaaagc
    50281 aacattctct ttgacagtag ccgtggcaat cgttaatgga atctgttggt cagtcagctg
    50341 gtcaagagtc gcttcaagcc cttttgtcaa ctgaagctcg ttttcatttt gcaagcaaag
    50401 catacgataa tagctttctt tttcttctga caatacggcg atctcagagg cggtcaaatg
    50461 ctctgaaatg aaatgtttca aaatctccgt attcgtccga ccatgaatat tttttaaaat
    50521 atcctcgtct gataaaccat cttttgtatg atcatgtatc atatgcagcc aagcagcttc
    50581 atgcagatga gagtccaaaa acattgttcc gttgaaatca aatataatcc ctttcatagt
    50641 tacgctccta tagtggtatt ttcggttgaa tcagcaattt gcagatcgac atattgtgca
    50701 tagtgctctt gaacctcccg cgagatctgg cgatccgtaa tgagcagatc gaaatcatgc
    50761 aaattataaa acacataaaa atcatctcga ttgaattttt tattatcaac gagtagatat
    50821 ttcttacggg aattatttag agcgatctgc tgtgcttctc cttcttcggt actgtaagta
    50881 gagatcgctt cgttgtgaac gccatttgaa ctgataaatg cttttgtaaa ctttagtctt
    50941 cttaaattgt cgttggtgat cggtccgaca aatgcgccgg tatttttccg gaaatcaccg
    51001 ccaatcagta gaatttctgg tccatctgct tgagcaagaa tatcaaaaac tggataatta
    51061 tttgtaatga tccgaatttt cttgttcagt aaatgcgtcg ccaatagttc gattgttgta
    51121 cctggtccta agaaaatcgt ttctccctcg tgaatcaagg aggctgctgt ggcagcaatt
    51181 tctttttttt cttgaatctg cagagtggct ttttcagtgt gagaaagttc ttgatctaaa
    51241 gtgtaggaaa gactttgagc ccctccatgg acacgcagca gcttgcccga tttttctaat
    51301 tcatctaaat ctctgcgaac ggtcatatca gaaacatcta attgattgat gatttcatta
    51361 acggtaagga ttcctttttt attgaccatt tctacgatag taagcaatct ttcttttttc
    51421 aacattgtct tcacctctaa tttaaggata atctatcata taaacggaca acagtcaatc
    51481 taattcgaac aaaagtaaac atttagggtg gtttttatgt ttgttacaat agattttatt
    51541 gctgttttct ggtttttatg attatttgtg tttgtttttg ttgacaaatg ttttggatgc
    51601 gtttacaatg caatcagtta gaaagagcga aaactgatta tagatttgag gagagatgta
    51661 catgcttaaa ttaccagaag attttatttt tggcggagcc acagcagcct atcaggttga
    51721 aggagccact aaggaaggtg gcaaaggcgc tgttgcttgg gatgactttt tagaggaaca
    51781 agggcgattc agtcccgatc cggcaagtga tttttatcat caatatgcaa aggacattga
    51841 attgtgtgaa cgttttggtg taaatggtct aagattatcc attgcttgga gccgcatttt
    51901 tcctgatgga gctgggaaac caaatccaga aggaatcgct ttttatcatc gtgtgttcga
    51961 agaatgtaag aaaagaaacg taacgccgtt tgtgacgttg catcattttg atacccctaa
    52021 acgtttgttt gaccatggag attttttgaa tcgagaaaca atagaagcat ttgtttccta
    52081 tgccattttt tgttttcatg aattcaaaga agtcaaggtg tggagtacct ttaatgaaat
    52141 ctatccagtt gcaaccaatc aatatttgtt aggtgttttc ccaccaggaa tcaaatatga
    52201 ttttacaaag atcgtcgcct gtcttcataa tatgatggtt gctcatgccc gtgtagtgaa
    52261 ctatttcaaa gaaaacgaac ttccgggtga aattggtgta gttcactcat tagagacgaa
    52321 atatgcggca acagacgcgc cggaagataa gcatgctgcc tttttagacg atgcattgtc
    52381 gatccgtttc ttattagatg ctacctattt aggctattat tcaactgaaa ccttgactgc
    52441 tcttgatgag atatgtgaag caaatcaggc cagctatcat tttcctgaag aagatttcgt
    52501 tgaattgaaa aaagcatcca cgcgtaatga ctacttaggg atcaatcact accaatgcca
    52561 ttttgtcaaa gcttacgatg gagaaaatgc aatccatcat aacggtacgg gtgaaaaagg
    52621 gacctctgtt tataaagtga agggaatcgg agaacgtatt tataaagaag gaattcctcg
    52681 aactgattgg gactggctga tttatccaga aggtctatat gacttgttgc tgcgaattaa
    52741 aagcgattac ccacattaca acaaaatcta tatcactgag aacgggatgg ggtataaaga
    52801 tcagtttgaa gatggcatta ttatggatca gccgagaatc gactatttga gagtctattt
    52861 ggaatcctta agcaaggcga taacagccgg ggtaaatgtg aaggggtatt ttttgtggtc
    52921 gcttatggat cttttctcat ggacaaatgg gtataacaaa aggtatggct tgttttatgt
    52981 tgattttgaa acccagaagc gttacccaaa agaatcagct tactggtaca agttggtcag
    53041 tgaaaccaaa acgattattt aataagtgat aatggaggaa gaaaagatga ataaagagga
    53101 attacaaatg cttggttttg agatcgttgc atattcaggc gacgctcgca gtacattatt
    53161 gaaattattg aaagaagtaa gacaaggaaa ctttgaacat gttgattcgg cgttgaaaga
    53221 agccgacgaa aatttaaccc ttgcacataa ttcgcaaaca aaaattttag cggaagaagc
    53281 atctgggaaa gagatggaga tgggattcat ttttatccat gggcaggatc atttaatgac
    53341 cactttattg ctgagagatc tgattcaaga ctttattgta ctgtacagac agaatcaagg
    53401 ataggagaag aacgctatgg atggaatcat taaacaaatc gaaaaaggga aaccattttt
    53461 tgaaaaaatc tcacgtaata gttatttagg agccgttcgt gacggatttt taacagcgat
    53521 gccagctatt ttattttcaa gcattttcat tttgattgct gcggttcctg agatttttgg
    53581 ttaccaatgg cctgaatctg tctccacatg gctatggaaa gtctataatt attcgatggg
    53641 tgttgtaggg ttactcgttt cagcaaccac tgctcgctgc ttggctgatt cgatgaatcg
    53701 tcgcttaccg aaaaacaaag taatcaacac cacctctgtg atgctggcct ctgtggtaag
    53761 tttcctgttg ttaagcgtct ctccgattga aggtggattt tcaacggaat atatggggac
    53821 aaagggacta ctggcttcct ttgtcgctgc atttttaaca gttaatttat ataagttttg
    53881 tgtgctgaaa gatattacca ttaaaatgcc taaagaagtt cctggaacga tttcgcaaac
    53941 cttccgagat atttttcctt tctctttttc agtatttgcg gccgttttaa ttgatttagg
    54001 cattcgacaa atcttccaaa tctcatttgc agaagcaatc attacggtgc tgcagccgct
    54061 atttacagca gctgacgggt acttaggaat cgctattatc tggggagcga tggcgctgtt
    54121 ttggtttgtc ggtgttcatg gaccgtcgat cgtggagccg gcaattgcgg caattatcta
    54181 tgccaatgtg gaaaccaatc tgcaattgtt caattccggt gaacaagctt ctaaagtact
    54241 gacggtgggt ttagggaatt ttgtaggaac tatgggagga actggggcaa cattggttgt
    54301 tccttttatc ttcctactct ttgctaagtc taagcagttg aaggcagttg ggaaagcttc
    54361 ctttattcca gtaagtttcg ctgtcaacga accattgcta tttgcggcac ccatgatttt
    54421 gaacccttat ttttttattc catttttgtt aacacctgtt gtaaacgttt gcctgttcaa
    54481 gttttttgtc gatgtattgg gcatgaacag ctttatgtac gttttgcctt gggcaactcc
    54541 agcaccgatc ggtttggttc taggaacggg catgggtatc ttagcttttg ttctagcagc
    54601 ggttctaatc gtcgttgact tcctgatcta tctaccattt tgcaaagcat acgatgctgt
    54661 cttagtagag aaagaagcac aaaaagcaga ggtgatcgca accgaggaag gtgcttctgc
    54721 cgatgtacgt gaggaagtac ctgtggcagc gagtcaagtt atcagcgatg caaataaaga
    54781 aatcaatgtg ttggtacttt gtgctggcgc agggacaagt gcgatgttag ctaatgcttt
    54841 aaaaaaaggt gcatctgaat cgaaagcacc gatcagtgca atggcgggtg cttatggttc
    54901 tcattacgaa atgctgcagg attttgatat ggtggtctta gcaccgcaag tcaattctta
    54961 ctatgatgat atcaaagaag acaccgatcg cttaggaatc aagctggttg cgacaaaagg
    55021 agcagaatat atcggattaa cgagagatcc tgaaaaagct gttcagttta ttctgaacca
    55081 atttcaataa aggaggagcc ataatgaaaa tgggaatttg gttgcgtaaa gctgttttat
    55141 ttgcagctgt gttaggggct ttgggggctg tttcaaaaac tgttgaagca tctgccagcg
    55201 aatttattcg cggagcagat atttcgatcc tgtcagatat ggaaaaatct ggtgcaaaat
    55261 attatgaaga cgatatttca aaagatgcct tagagatttt aaaaaataat ggtgtcaact
    55321 atgttcgact gcgtttgtgg caggatcctt ataatagtaa tggagaaagt tatggagcag
    55381 ggacaaatga tctggaaacg acgattgacc ttgcaaaacg agcaaaaaat ctgggactta
    55441 aggtgctgct ggattttcac tacagtgatt tttgggttga tcctgggaaa cagaatcttc
    55501 ctaaagcatg gcaaggtctg acctttgaag aaatgaatac ggcattgtac gactatacaa
    55561 agaacgttct gtcggaaatg aagcagctgg acgtttatcc tgatatggtt cagatcggca
    55621 atgaactgaa tagcggaatg ctctggcctt atggcaagtc ttggggagaa ggcgggggag
    55681 aatttgatcg attggctgct tttttgaagt ctggtatcca agctgttcga gacactcaac
    55741 ctaaaacaac tccagtaatg ctccacttag ctgatggtgg cgatacagga gcatttactt
    55801 ggtggtttga tgaaatcacg agtcgaggtg tgtcatttga tttaattgga gtgtcgtatt
    55861 atccgtattg gcacggttca atgaatgaac ttcaaaccaa tatgaatgcg atcagccaac
    55921 ggtatggtaa agaagtgatc gtagttgaaa cagcttatgg gcatacaaca gcgaatgccg
    55981 atactatgcc aaatgctttt ggtgaagccg aagcagctgc ggggggatat gaaccaacac
    56041 cgacaggaca agcagagtat ttgctggatc ttgccgatcg gattcaggca gtaccgaata
    56101 atcgcggggc gggcttcttc tattgggaac ctctttggta caacggaaat gtgagttggg
    56161 caacacaagc aggtatgaat tatctcagtg ttcaatccac tatgggaaac gaatgggaca
    56221 accaagcgat gtttgatttt gctggaaacg ccttgccaag cttgcgtgcg tttaaacaag
    56281 caggggcgca aataaatcta gttaaaaatg caagtttcga aagcgatgga ccaacgacca
    56341 gtccttccaa ttggcaaacc tggtttcaac aaggaaccgc taagggtacg atcaaaacgg
    56401 aagcgggcac tttttttggg gactacaaac taactttttg gcaggatcaa gcatacgagg
    56461 catcagctta tcaaaatgtt agtggcataa gcaaaggaac ttacacattg agtgcctatg
    56521 taatgtctgg gggagagttt gatactaatc agttatatat caaaaattat ggtggagcgg
    56581 aactaaatac tgcggttgtt aaaacaagtg aatggacaaa aattacaatc aaagacattc
    56641 caattacaac aggtgtttgt gaaattgggg tttatagcaa ggcttcagga aatgcttgga
    56701 cgaacgttga ttttgtttca ttggtgaaac aatagactgc ggatcgtttc gattcaagat
    56761 cggaggttcc cttcagccac atcgttagcg tagaaggcag gaatcgaacc tgcacctcgc
    56821 ctttgccaaa aataaccaga aacgatttcc agtcattttt accaaaacga gtaaagcacc
    56881 agacttcatc tacactttgt attatgctaa agagagttca acgatttcgt aagaagcaat
    56941 gaaaaaattg caaaaagttg tgcagataac ataaagtttg tttaagaaag ggtaacctta
    57001 gaattccgtc gtgaatatga tttgagcact tagatggata gaaaaaagtt ctcggaaaac
    57061 agttcgtttt tcgagaactt ctttttatga taagaatgaa acaaattaac ttatattata
    57121 gtctcttttg gtagggaacc atcttatttt taatgaaaat caagcatttt agctattgaa
    57181 gaatgttgat ttatagggat tccccctcca tattatgttg gctctttatt cccactctgt
    57241 tttcaacgta aagtgtataa aacagaatgc gatactatca agggagttaa aacaatatac
    57301 agaacagtaa aacactataa ataaaaataa aagtgcaatt tttgcaccta atcatactct
    57361 gtttatatat gaaaactaga ttctgaatcc aatatttggt taacgagagg cgttcgaatt
    57421 tgaacgtctt ttatatatta ctttcaaata aatatgaggt agaatactat ctattttctt
    57481 tttaacccaa ttgttataat ggagagtgta aaatattttg tgtaaataga aaaaaggaag
    57541 tcccttctgt agaatagagt taccacaaca cattc
//
LOCUS       DAIGQM010000011        57505 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.011, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000011 DAIGQM010000000
VERSION     DAIGQM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.011"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(61..2424)
                     /locus_tag="NOA48_000602"
     CDS             complement(61..2424)
                     /locus_tag="NOA48_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HCI0788892.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="NOA48_000603"
     CDS             2872..3093
                     /locus_tag="NOA48_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0788893.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOA48_000604"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOA48_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCI0788894.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOA48_000605"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOA48_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCI0788895.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="NOA48_000606"
     CDS             complement(5894..6205)
                     /locus_tag="NOA48_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCI0788896.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="NOA48_000607"
     CDS             complement(6202..6495)
                     /locus_tag="NOA48_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCI0788897.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOA48_000608"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOA48_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCI0788898.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOA48_000609"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOA48_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCI0788899.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="NOA48_000610"
     CDS             complement(8333..12685)
                     /locus_tag="NOA48_000610"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCI0788900.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="NOA48_000611"
     CDS             complement(12897..14606)
                     /locus_tag="NOA48_000611"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCI0788901.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOA48_000612"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOA48_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCI0788902.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="NOA48_000613"
     CDS             complement(16103..16903)
                     /locus_tag="NOA48_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCI0788903.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="NOA48_000614"
     CDS             complement(16900..17712)
                     /locus_tag="NOA48_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCI0788904.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOA48_000615"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOA48_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCI0788905.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="NOA48_000616"
     CDS             complement(18467..19189)
                     /locus_tag="NOA48_000616"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCI0788906.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="NOA48_000617"
     CDS             complement(19325..20206)
                     /locus_tag="NOA48_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCI0788907.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOA48_000618"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOA48_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCI0788908.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="NOA48_000619"
     CDS             21446..21925
                     /locus_tag="NOA48_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCI0788909.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="NOA48_000620"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="NOA48_000620"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCI0788910.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="NOA48_000621"
     CDS             23226..24011
                     /locus_tag="NOA48_000621"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI0788911.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="NOA48_000622"
     CDS             complement(24357..26048)
                     /locus_tag="NOA48_000622"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCI0788912.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOA48_000623"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOA48_000623"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCI0788913.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOA48_000624"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOA48_000624"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCI0788914.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOA48_000625"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOA48_000625"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCI0788915.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="NOA48_000626"
     CDS             30332..31033
                     /locus_tag="NOA48_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0788916.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOA48_000627"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOA48_000627"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCI0788917.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOA48_000628"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOA48_000628"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0788918.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOA48_000629"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOA48_000629"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0788919.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOA48_000630"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOA48_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCI0788920.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="NOA48_000631"
     CDS             complement(34528..35508)
                     /locus_tag="NOA48_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0788921.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOA48_000632"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOA48_000632"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCI0788922.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOA48_000633"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOA48_000633"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCI0788923.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38265..38432
                     /locus_tag="NOA48_000634"
     CDS             38265..38432
                     /locus_tag="NOA48_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCI0788924.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38494..40305)
                     /locus_tag="NOA48_000635"
     CDS             complement(38494..40305)
                     /locus_tag="NOA48_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCI0788925.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40302..40667)
                     /locus_tag="NOA48_000636"
     CDS             complement(40302..40667)
                     /locus_tag="NOA48_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCI0788926.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40830..41225)
                     /locus_tag="NOA48_000637"
     CDS             complement(40830..41225)
                     /locus_tag="NOA48_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0788927.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41243..42205)
                     /locus_tag="NOA48_000638"
     CDS             complement(41243..42205)
                     /locus_tag="NOA48_000638"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCI0788928.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42205..42417)
                     /locus_tag="NOA48_000639"
     CDS             complement(42205..42417)
                     /locus_tag="NOA48_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCI0788929.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42438..43136)
                     /locus_tag="NOA48_000640"
     CDS             complement(42438..43136)
                     /locus_tag="NOA48_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI0788930.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43156..43698)
                     /locus_tag="NOA48_000641"
     CDS             complement(43156..43698)
                     /locus_tag="NOA48_000641"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCI0788931.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43830..44834)
                     /locus_tag="NOA48_000642"
     CDS             complement(43830..44834)
                     /locus_tag="NOA48_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0788932.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44831..45820)
                     /locus_tag="NOA48_000643"
     CDS             complement(44831..45820)
                     /locus_tag="NOA48_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0788933.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45817..46623)
                     /locus_tag="NOA48_000644"
     CDS             complement(45817..46623)
                     /locus_tag="NOA48_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0788934.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46789..47745
                     /locus_tag="NOA48_000645"
     CDS             46789..47745
                     /locus_tag="NOA48_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0788935.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47822..48340)
                     /locus_tag="NOA48_000646"
     CDS             complement(47822..48340)
                     /locus_tag="NOA48_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0788936.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOA48_000647"
     CDS             complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOA48_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0788937.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48805..49251
                     /locus_tag="NOA48_000648"
     CDS             48805..49251
                     /locus_tag="NOA48_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI0788938.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOA48_000649"
     CDS             complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOA48_000649"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCI0788939.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOA48_000650"
     CDS             complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOA48_000650"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI0788940.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52974..53061)
                     /locus_tag="NOA48_000651"
     tRNA            complement(52974..53061)
                     /locus_tag="NOA48_000651"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53027..53029),aa:Ser,seq:cga)
     gene            complement(53206..53772)
                     /locus_tag="NOA48_000652"
     CDS             complement(53206..53772)
                     /locus_tag="NOA48_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0788941.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54028..55359
                     /locus_tag="NOA48_000653"
     CDS             54028..55359
                     /locus_tag="NOA48_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HCI0788942.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55325..55675
                     /locus_tag="NOA48_000654"
     CDS             55325..55675
                     /locus_tag="NOA48_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0788943.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55767..56186)
                     /locus_tag="NOA48_000655"
                     /pseudo
     CDS             complement(55767..56186)
                     /locus_tag="NOA48_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(56187..56531)
                     /locus_tag="NOA48_000656"
     CDS             complement(56187..56531)
                     /locus_tag="NOA48_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCI0788944.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56797..>57505
                     /locus_tag="NOA48_000657"
     CDS             56797..>57505
                     /locus_tag="NOA48_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0788945.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT        16221 a        12140 c        10050 g        19094 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 tccattttcc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagcg agggcgttac
    34681 atatttcgct acactgacat cattgaagcc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aagtgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgccggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct aggcgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat cgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccatttt tccaatactg agttagctgc ttcaataagc
    36061 aagtttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatcttc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaattggt
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg ggaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taatcgcttt gatatctgtg tattcaggtt tccagcccag aatctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaaggctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tctttcggct ctccataagt tgctgcagta gaagagaata
    37681 cgattttatt cacgttgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattct atataattta aaaaacgaag tttactttta tggtgaaaac
    38101 aaacaaagta aaatttcgta aattcatatg gtaaatttat aataaaacat ttagtaaaca
    38161 ttttcaagga ttttttgcaa aggtttacaa acaaacgtaa aactagcctt tttttctctt
    38221 ttgttccata atagatataa caaataataa atgaggtgga ttcaatgaaa aaatttgtat
    38281 ctggaatatt agtaggaagt ctggcaacag ccgctgccgt tgctggtttg gttgcttctg
    38341 tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc aatgatcgaa gaaaaccgta
    38401 aaaaagcaat gcgtaaacgc gtttctcgtt aataattatt taaaaatacg catgaagact
    38461 ttctaaaaaa cagataagtc atcatgcgta tttttatttg tcagtcaata taagttgtgc
    38521 tattttatct gcctgtctca gattccatgg atctgtataa ggtctagcta ctgctgcagt
    38581 tagccaatcc acaccttcaa caggtattcc atagcaataa aagtcagact ggatttcccc
    38641 tgaagcatca atcacgcgat tcgtacctcg ctcaacatct atagcttctg aatgataact
    38701 tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg ttttccttca aattttttat
    38761 gacaggatta cttgaacgag aaaagcttgt ttgtggcaat cgagcttcaa tcaaatagcg
    38821 actgctgatt tctttatctt gtagagaaat aacatagcgg ttgtgctttt gctgaatatc
    38881 aaatggcggt tcgatcaaat gaaaaatacc cgcatctatc agtgctgcta attctttcgt
    38941 ccgaatgatt ggcggaccga tcgttaaaaa gctatttaga tgagtaaacc atccccatag
    39001 tatttctttg tattccttag cagaaaaaac gtgccattca atagcctgcc ggattggatc
    39061 acgccagtct tttaatgcat caaatgttga agcaaatgct cctgtgcaat tgcctttttc
    39121 cgcttctttt atctgccctt caataaatat tcggctagct tctgaaaagg gctcattctg
    39181 ataggcaaga ggagtttcta aatacgacca atcccatcta taagggatta gtgctggatg
    39241 ctttccgaga cactcctctg aagagaggga gagaaaatca tgctcaaaat ttttctttgg
    39301 aatcggcaag tgatattctt cgatgatttt cttgtaataa aacaactcaa cgtctttttt
    39361 cagatagtca aaaaatgttt cgccagtcaa aaatcccgac tgatgccatt gctccaggtt
    39421 ttcttttgtt agtaaccgtg gccatgccat tgctccgcct tgcttttgat ttcttcctcg
    39481 agggtaataa gggagccccc ttcttgatcc actgtataca atcggttcct tgcctgatgg
    39541 atgatagacc agttttccct tttcgttctc gaagcgccct cctcttgata ctgtaaacaa
    39601 tccgacataa tcaaaaaaac ttaagcctag acctcttaaa aagacatttt ctttaggcgg
    39661 tatcttcgaa agatctacat ctgcaggatt agaaggaagc tgatacagta aaacattttt
    39721 ctttgcgtag tctacccaca ctctttcttc ttctgtctca tcattttccc agtgaccgct
    39781 tgctaaaaca agctgatcga tagaatagct ttgctgatct gtctgtaaaa gataaccatc
    39841 ttttcttttg cttacttttt ttactaaaga ataaacaaac tgaatagaag ctggaaattc
    39901 ttcttgcaac tttgagaaaa accagcgttg atagagtccg tataaacatc gagtagattg
    39961 ctgatctttt tccagacgat tgatttcttc tataattagt tgcttatttt tggttaccgt
    40021 ctgttcgata taatctgtag caggtccttt actccattga aacaagttgg gtccctgtgt
    40081 taccaatcct ccactggaca atgtttcatc tgtaaaaagc gtcacttgtt gagaaacaga
    40141 attcattaat aactccggtg gctgattcaa ccgccaaact cgacctccag gaccattggg
    40201 atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta ttatggagaa tcctttctgc
    40261 tacacttaat cctctaggtc cggcaccaat gatccctatt ttcatttgca tgcctccatt
    40321 tcgataaatt ttttcaataa aacagcatgg ttctgatgtt cattttttgc accataaaca
    40381 aaagtaatga ctggatgttc tttcataagt tgactgagtt taaaaatagc ttgcttcttt
    40441 tcttcttcga aaatcaattc ttgctggtat ttctttgcaa atgaagcaaa tcgttctggt
    40501 acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa tttctttcaa ccacagatct
    40561 aactgcgctt tttcttttga aattcctcgt ggccagaatc tatccacgag tattctatag
    40621 ccatcctctt tttcagcatc aaggtaaaca cgttttaatt tgatcatagt tgtttccttc
    40681 tttctacctt ttcgcttagc ttatatatgt agataatagc acaaaataaa aaaaatgaac
    40741 ggcacaacta tccattgcgc cgttcatgtg atcttggtca aaatctaatg attgattcgg
    40801 tttttaaagc tgtcatacaa tcatctgttt tatacttttt tacttttgat ttttccagac
    40861 catccgtcat atccaccctt aagtaaataa atctcttgat aacctgcttt acgtaattta
    40921 tttgctgtac ggatgctcaa acttttcttt tgatcgtaaa tatagacagg ctggtctttt
    40981 cgaatagatc ctaatgaatc tttcaaaaca gtgtaaggga tgtttcttgc acctaaaata
    41041 tgcccagcat caaacacatc tttttcgcga acatcgatta cttgtgcttt tctcattcct
    41101 tctcgaaatt cttcttctgt caaagtcgtt gctgaacgtt tggccattac tcgtagatag
    41161 acttcccaaa ggatgattgc aagcacaatc aatagcaaaa tgatattaat tacccataaa
    41221 accatgtaat gcctccgttt ttttaagcaa atttcaaggc taatgaggca gcaccaatga
    41281 caccagcttc attaccaagc tctgctaatt tgatttttgt tgattctctt acttgcggga
    41341 aagtaaattc tttaaaatat ttctctacac ggctacgtaa aaattctcct gctgccgata
    41401 ctcctccacc taacacgata cttgacggat ttaatgtatt ccccaagttt ccgcaagcta
    41461 aacctaagta gaagcatacg cgatcaacaa ccatcaatgc aaacggatcg tcttcttgag
    41521 ccatttcaaa gatatcttta cttgttactt cttctccgtt gtctagcatt gctttcagtt
    41581 ttgaatcccc tgcgtattct tctgccaaga aacgacctag gcgtaccaca cctgtagcgc
    41641 tagatacagt ttctaaacat ccgcgtttac cgcaagtaca ttcgaaccct tcaggatcca
    41701 cagtgatatg tccgatttct cctccagctc cgctcacgcc gtgaatcaaa tttccgccag
    41761 caacgatacc tccgccaaca cctgttccta gagtaacgaa tacaacgtct ggatcgtttt
    41821 ctccagcacc tttccatcgt tcacctaaag cagcaacatt cgcgtcatta tcgatagcga
    41881 atttgattcc tgttcctgcc tcgatcagtt ttttcacaaa ttgaacttct gtccagttta
    41941 agttatacgc accaataacc gttccagctt cgctgtccac gcttcctggg gtacccatgc
    42001 cgattccgat aaagtcttcg gctttcatat tatataaatt caaacgatga ttgattgatt
    42061 caatgatttc aggaacgata tgcttaccat catccaaaat attggtatcg atgctccatt
    42121 tttgctgaat ctctccttct ggtgttaaaa ttgcaaattt tgctgttgtt ccacctaaat
    42181 caatcccaat aatcttcttg tccattacaa atttcctttc tttcggcttt cttcaattcg
    42241 gtgctctctt tttaatatgc gccacgctgt catgtatgta tcatgatcaa tcaaacggct
    42301 atcatacaga ttacgcaatt cgatagtcat taattcaatg tcatagatgc gtgcacccac
    42361 atagataaag atgccaaatt ttttgaacag ctgctgtaca tcatataagc tctccatctt
    42421 taagcacttc cttcatatta tacaagtaaa ccatattttt ttaaacccag taaaatacat
    42481 attacaaaaa gaaatacaaa aactagtgta gaaagaatcc tttggtgtat cgaatagctt
    42541 gtctgttgtt tcggtagacc caaaacattc cctaacacta atccgccaat tagcccaccg
    42601 acatgtcccc aaacatctac agaggtatcc agaagaccaa aaacaaatgt caacacaata
    42661 aataaaagaa aatgtctgac tagctgctgg atcgctgggt tatgtttaaa atgaaaccct
    42721 aagataaaca acgcaccgaa caaaccgaat atcgaagtac ttgcaccacc agacagaaca
    42781 ttcgcttcgt taaaagcaaa gcttgctgta tttcccatta tcccgctgaa catataaatc
    42841 aagaaaaaac gccaatggcc atagattgcc tcgatttgct gccccataaa atacagtatc
    42901 agtgagttca ttacgaaatg catcagtcca aaatggatga agattggtgt cactaaacgc
    42961 caccattcat tgaagtgaac aagataagga ccatacattc cggcataata agggatctca
    43021 agtcgcggaa ataattccat catgaggaag accgctgtct gtatccctaa aaaagcatag
    43081 gtccataacg gtcgtcttaa ccatgcacgc aattttattt gctgttgata attcatgaaa
    43141 acctcccatt tcattttagt caataaacaa ttgttggatc ttctgatcaa agctctccgg
    43201 ttgccattgt tcattcaatt gttcacgaaa aacaaggcta catgtttttt tatgaaaatt
    43261 atttaaatac cggtcgtaat aaccaccgcc aaaaccgatt cgataaccgg ctctattgta
    43321 gataatacct ggtacaatga ggagatcgat catctccggc aaatagagct tctctgattg
    43381 tggctcaaga acaccaaaac tcgaacgtac aagaacggac tgttcatcca tttcataaaa
    43441 cgccatctga cgtttcggca aagttttagg tacaactatt ttcttttgtt ctttttctgc
    43501 tcgttggata accggctgtg tatccagttc aaattcattc gataaagtcg tccctatcac
    43561 ttttgctgac ttccagtact cgctggcgaa tagctgttta tagattcgct gttctttttc
    43621 ctttttcttg ccacttttgg ccagattttt cagcttttcg attcctttcc ggcgtaatct
    43681 tactttcaat tggtccaaaa actcaccctt ccttctctca taaaatggta taggaaaaaa
    43741 agaaaaatag caatcgaact ttcaaataaa tgcataaata gaataaaaag aagacctaga
    43801 aatgattggc cttccttttt taatgaattt caactgttca gcgcgtgttt ttgtctgata
    43861 aaaagtgcat acagaaaata tggcgcacca aaaagggcaa tcaaaattcc tgtaggtact
    43921 tccccactta gtagaatcac tctagcaacc atatctgcac taagcagaaa aatggaaccg
    43981 aacaaaccgc tcagaacaaa ggtccagtta ttttctttac gtacgactag cttcgcagca
    44041 tgaggagcta gtagtcctac aaaagataaa ctacctgtca ccgctacact accgcttgcc
    44101 aaagcaacag ctaacaacaa aaggattttt tgacttttag ccacgttaag gcctaatcct
    44161 tgcgcgcgtt cttgaccaaa tgatagcaat acaatcctct gtgcataaag tcctcctagc
    44221 ggaattaaga taaccgccca tggaagcaat gcccaaacat aaggccagct cgcaccccag
    44281 attgatcccg ctaaccatgc attcacaaat ccataatttt ccttagataa ttggatcgtg
    44341 catagcaatg ttaatgcaga aaggccggca ttaacggcaa taccggacaa taagattcga
    44401 ttcataccca aaaagccatt tcgatcatag gccgcaagat agacacagca agcagctaaa
    44461 acaccaccta gaaaggctac aactagcaat agaaacggca gcgaatagtg cgaaaagaaa
    44521 cctaaataaa gcatcactaa aaatcctgct ccggcattaa tgcccaatat actagaatct
    44581 gccaattcat ttcttgttac tccttgcaag atataaccag aaacgccaag acaagctcca
    44641 gctaataaac tgatcagtaa tcgaggaact cgaaattctc taacaatcag cgccaaagaa
    44701 gatgattctt tccctatgaa cgtggcaaaa agctgatcca ggtaaataaa aggcgtacca
    44761 atcattaaac tacctataga caggatgaca agtacaaaaa gcaagaaata gaacgtccaa
    44821 tatatttttt tcaccgttgt tccctcctta cttgtatcag taaaaacgga acgccaatca
    44881 atgcaatgac taatccaaaa ggtgtttcaa aagggggatt gatcatcctc gctgtaaaat
    44941 ccgccaacat aaccaatcca ccgccaacta aaaaagagac aggtagaaca taacgatagt
    45001 ccgttccaac cattccgcga acaactggcg gaaccaacag cccaataaat gaaacaggtc
    45061 cgactaacga aacggcaatg gctgctaaca ctgcaactag acagaaaaca atcaaccgcg
    45121 ttcgtttagg atgacttcca agagctaatg catgtgtttc actcaaatga atcaaagata
    45181 ttgcttttcc taatgaaaaa gaaaccaaaa cagcaagtat atataaagga aacaatactg
    45241 ctaattgttt ccatgtgata ttggcagctc cgcctacaaa ccaaaaagca agatcctgct
    45301 gcagattaaa gaattgggta agtgcttggc tgatagcagt aaaaaaagaa ctaatagcta
    45361 cgccagctaa aatcagctgt aaaggattca tgcccatttt cgaaaactgc aaaaaaccaa
    45421 atacgagcaa agttacagca aaagaacctg ccaatgacat tagaaacaca gaaaaatcag
    45481 aagctttagg ccaaaaagca aaactaaggg ccattgccaa cgaagcaccc gcgttgattc
    45541 ctagtaagcc tgaatctgct aaaggatttc ttgtcactcc ttgcatcaat gcaccgctca
    45601 atgcaaaaca actccctaca agaaatgctc ccgccacacg aggcaaacga atatttcgta
    45661 tgatttggtg actttgtttt gatctatcaa aatcaaacaa cgcctgccaa aaatctgctt
    45721 ttcccacagt cgctgcgcca tttgaaagag caacaaaaaa aataatcaaa agaacaaaac
    45781 agaccaaaag caggagtcta tttttcttca tagtcctcat aattgatcct cctgctcttt
    45841 tggcaacaaa tcataggtta gaaaaactgg tttatttgtt cttggaagcg tgacaatcgt
    45901 tgcatcaatc tcaaatattt ttttcataca ctcttttgtg atcacttctt caggtgtacc
    45961 ttctgtgatc aacttaccgt ttttcattgc taataaataa tctgaaaaac gtgaagcatg
    46021 attaatgtca tgaatcgaca tcaagatcgt tgtttgtttc atttgattga tttcagtcaa
    46081 taactgtagg atctctaatt ggtgtgccgg atctaaaaat gttgtcggtt catccaagat
    46141 caagatatct gtttcctgag caagcgccat agcgatccag acacgctggg tttgtccacc
    46201 agacagcgtt gcgatatccc gcatacgaaa tccagctaga cctgtagcat ccaacgccca
    46261 ctcaattgct tcatgatctt gcgtgtccat gccactgaac agtttttgat aagggtatcg
    46321 tccgtaagat actacttctt ctactgtcat acctgtaggg tgttcactag tttgtgctaa
    46381 taatgcaatt ttttttgcaa gttcttttga actgtatgta gagatatcag agttattgac
    46441 aatgatcttt cctgatttca caggtagtat acgggtaaaa cttttcaata aagtagattt
    46501 tccacttcca tttggcccaa tcaaactagt gattttccct tcaggaatcg taacagacat
    46561 gttttcaatg atttttttgt tttcgtagcc ggctgcaatg tcagctgctc ttaatctcgt
    46621 catttcaccc atcctttcgc tgaaaatcat tctcaattat gacgctgttt caacatttcg
    46681 tcaagcgcta ctttcatatc tatagccaaa tgaagcggtt gacagcgttc gaaatatcag
    46741 gaataataac caatgagaaa gattctcaat tatgttagga ggaaagaaat gaaattaaaa
    46801 acaaaagtat tcacattatc tagcatattg ctgctggctg gagtactgag cgcttgctcc
    46861 ccctcttcag ataaagaaac agctacaact gccaattcga cgacttcatc caatagtact
    46921 catacagtca cagatacact tggacataaa gtagagattc caaacgcgcc caaacggatc
    46981 atcggcagtt acttagaaga ctatctgatt gcactagggg aaaaacctat cgcccagtgg
    47041 actgttggca gtggttccat tcaagattat ctgcaagatg atttaaagga tgtcccaacg
    47101 atttcttatg accttcctta tgagaaagtg ttaagctttg agcctgattt gctgttgatt
    47161 tcttcttccg ctactgtcga aggcgggaaa tacgaacaat atagcaaaat cgcgccaact
    47221 tatgttgtaa aaaacggaac agatgtcaca tgggaagaac aactaaaaga tgtcggcaaa
    47281 gctttggcaa aagaaaaaga ggcagaaaaa atcatttccg attatcaaaa atccatcaag
    47341 aaaactcgag aagaactagc agataaaatc gagaacaaga cagctgcagt gttgtgggtg
    47401 accaacaact cagcctttat ggtcagcaaa aatcggtcaa gtggaagaat cgtatacgac
    47461 gatctggaat ttggtgttcc tgatctagtg gaagaggtct ccaaaaaagc cacttctgac
    47521 tggtctgctg tttcctctga aaagctagct gaattagatg ctgactacat catccttgtg
    47581 aacagtgaca aagatgctgc catgttcaat gaaccaagct ggaagaatct aaaagcagtg
    47641 acagacaatc atgtactgca attcggacct gaatctagtt ggctatataa cggacctatt
    47701 gccagtcagg aaatggtcaa tgatatcaaa gaaaaactaa attgatttta actaaaaaaa
    47761 gcatcttcac gattagtcgt gagatgcttt ttttcttatt aacaaactag acgcatagat
    47821 tttattcttc ttttgaagca accctatttt ttactctttc ccatttttga aaacgatggg
    47881 catatagatt ttcttgatcc gttatcccct catactcctc tataagggcg aagtctgaaa
    47941 aatcaatatt cccaatatac gtatcgcctt caaacgtgct atcgatcaat gttcgccaga
    48001 tccgaccagt gtaaggaaga agttcttgaa aaatccgact accacccgaa acatagatat
    48061 cttctgagat cgtttgacta tacgacaaaa gttcatcgat cgaatgcatt acttccgcat
    48121 tttctttcgt gcgaaaattt ggttgcgttg tcaacacgat gatatggcga taaggaagtg
    48181 aaagatcccc cattccttca taggtctttc ttcccatcac taaaattcga tccattgtgt
    48241 gttcgcgaaa gaaacgcata tcatttggca atcgccatgg taacaaacca tttttgccga
    48301 tcagaccatt tttatcttgt gcccacatgg aaataaacat attatccgct ccttatgatt
    48361 ttagatgttt tgagataaaa aaagtctcaa ttctttgacc agcaaggaat tgagaacttt
    48421 aaaaacatta ttttgtttca cggtgcaaag taactttgcg ttcgcgtggg caatattttt
    48481 gtttttccaa acgatcagga ttgttacgtt tgtttttgct tgttagatag ttacgttctt
    48541 tacaagaagt acactctaaa gtgatgttta cgcgcatgtt tttccctccc atttttacaa
    48601 gaatcctcta agatgactct cagacttgat tatcttacca tgattttttc tagattgcta
    48661 gtgtttttca cgattttgtt aagtaaaact acttgacgat aaatacaacg gttttacttc
    48721 tcaaacaaaa tctttttctt tttgtataaa tacccttaca cttgtttata tagattatgt
    48781 tttttaataa agggggatac taatatgcca tggaacatga aggactttcc tgcatcaatg
    48841 aaaaacttag ataaattgac aagaaaaaaa gcaatcgaca tcgcaaatgc attattagat
    48901 gaagggtacc ctgataaccg tgcgatccca attgccattg atcaagcaaa aaaatggtat
    48961 gaagatgcta gtgaatcaga aaaacgaact ttcgaaaaag aaaaaaatcc aagcaagacg
    49021 gatgaacacg atacgaatcc tcgtgctgga aaactgcttg attcagatgt gatcgtagaa
    49081 tatgaggaag aacaatggat cgtgaaatct aaaggggcaa aaaaggcaag caaccatttt
    49141 gatacaaaaa aagaagcaat cgaaaaagga aagcaagtag cacaaaacaa agaatcaact
    49201 ttgttcattt ataaaaaaga tgggacaaaa gaaaaagaaa tcgattattg aacatatgta
    49261 aaggggttgt gacgaaaatc gtgtcacaac ccccttatgt tcgaaacaat ggtgttcctc
    49321 tgccaactcc gaaccataag tcataatatc tataaaacgg gaagagctgt tttttgaaat
    49381 tgtttcttat cactcagtgt taaacggtag gagaaaacct cttttttatt gatatttgat
    49441 tttcatcaaa cagtcacata gtcgattgct tctgcttgcg gaatcgtttc atctacaaag
    49501 tagactttat accatgtcaa gaaactgaag attgtccaga tttttctttg ctcttcttta
    49561 cgtccttcgt gatggtcatc tagcaacttc atgatttttt cttgatcaaa aaattctttt
    49621 gcaaaatctg cttcgaataa tgctttgact tgttcgtagc cgtgttcttc tttcaaccaa
    49681 gctttgattg gcacagggaa tcctaatttc acacgattcg accattcttc cggaagatgt
    49741 ttgttcgcag cttgtctgaa aatatctttt gtgttgtttt gattcaataa aaacttactt
    49801 ggtatttgtt gagccaattt catgacttcg atatccaata aaggtactcg gacttccaaa
    49861 gaacttgcca tagaaagttt atctgccttt aacaagatat cttttggcat ccattgatga
    49921 agatcgacat attgcatctt attgacttca tctttgattc cttctgtttt ctcgtaatga
    49981 acagtcatga tttcatccac agatggtgct gtttgatatt ttggtgttaa cacttctgat
    50041 gcttctgatt cttcgaacac tcgagcatga ccgataaaat attcttttgc aggagcaagt
    50101 gattcatata aatggatccg tccatggaaa tttttcattt ttccgatttt acgtcctaaa
    50161 ttatagcgtg ttccttttgg taattttttc aatccttgag caatcacacg gatgaatttt
    50221 gaattcgtat ggaatccata cgtttggtat cccgcaaaca gttcatccgc cccttctcca
    50281 gattggacta cccgcacact ttgtgaagca agatttgcta aaaagtacaa aggtacgcaa
    50341 gaaggatttg aatcaggttc atctaagtga tactggatca aagggaatgc tttgaacgac
    50401 atgtctccgt cgatcactgc tgctgtatta tctaagtcca atagttcggt tagttttctg
    50461 gcttcaatcg cttcattata ggttttatca tcaaacccga ttgagaaaga atgatctggt
    50521 ttcaatacag aggttacata actggaatca accccgctgg ataagaaaga accaacttct
    50581 acatcactga ccgtatgtgc ttcaatagaa gcttgaacgg tttcgtcgat tttttcgatc
    50641 cattcttgtc gggaatgcgt ttcttttgtt tcaaaatctg catcccaata ttgctgaatg
    50701 tctatttttc catctttata cgtataataa tggccttcag gcaaacgata gacatctttg
    50761 aagaatgttt cgccgtttaa tggagaatat tggaaagtca tataaggttt caacgcttct
    50821 ttgttcaatt ctttgttaaa atcaggatga ggcagaaaac ttttgatttc tgaaccaaac
    50881 ataaatgttc cgttcatttc tgcataataa tatggtttga tcccaaagtg gtctcttgca
    50941 ccgaataact cattcttttc attatcccaa atagcaaaag caaacattcc gcggatcttt
    51001 tgcaataatt ctgttcccca ttcttcgtaa ccatgcaaaa ggacttctgt atctgcatgt
    51061 gtttgaaaaa cgtggccagc tgcaatcaat tcttctctca aaggctggta attatagatt
    51121 tcgccattaa aaataatgat ctttgtccga tcttcattgt aaataggctg agtaccgccc
    51181 tctaagtcaa taatacttaa tcttctgaat cctaaagcaa catgtttatc gatatattct
    51241 cctgaactat taggtccacg gtgaacgatt cgatccatca ttgtattaat aattgttttt
    51301 ttgttgtcct tgtcgttaac aaaacctaca ataccgcaca tttaactttc acatcctaat
    51361 ataaaattac tgtttatttc attcatatgc atcttatcat agaataaata gcggacgaat
    51421 attttctctc ttacaatttc gtcacgtgaa aacaaaagat gaaagtttct gtttttacag
    51481 aaaataaagt cccaatatct aatttaccat gttttctttt ttgaggctac cttattctct
    51541 tcgtgttaaa aaaatattag tggatgctat ttccaaaaaa accagcaaaa aaagacacga
    51601 cctaaagatc gtgtctaatt atgactgtat cagaaaatat gataccaaac ggatctattc
    51661 attaattaat tgacatagtt tatctgttgc tcttttatga ctggataact gaccaattca
    51721 tgacgatcca agtcttcttt attcatattt acagcagtaa tttgactgtc ttcatacgta
    51781 cgataataat aaatcccttt atcaacgtta cagcaagaag aataaatcgt atattcgtat
    51841 tttctttctc cagtatcgca tactcctttt tgttgctcga ctgagcctag tatatgaaaa
    51901 aattgactga tactttcaga ttctgaatca cctgatgcag cattcatttt agtaaatgtg
    51961 gcttttacaa atcgagaaac agaagagaga tctccaggta agcccaatcc tcccatccca
    52021 cgactataaa cattcaagct gatctggttt gaaaaatgat tttctggtgt tccatttgat
    52081 agcgagcgat aattgttcag attaaataat tgataatcaa atggcggatt atttgtcaac
    52141 acaccgacag gattatcata taaatgaagt ccatctttca tactttcaat tactatcgat
    52201 ttttctttat cagctaataa ccagtgtaaa ggtgacaagg gtagtttttc actaaaatcg
    52261 atattgacta gattgatagt agccaataat tctttagctt cgtctatggt tgagcattgc
    52321 cctagtatcc atggaataaa ctcaaatggt gcaacgttat cttttccttc ttgtaattct
    52381 ttataatcag cattgccagg aaaattcagt cctgccatac tcaacccttt ttcatttgta
    52441 gcctcataat agagtggata gttggatacc ccagctgcta ttcctatcat tgcataatgt
    52501 ttatctaaat tttttacctt tctaaaatcg aaacgataat ttcttggagt aatagtgacc
    52561 acttcattat aagacatctc ataatcaaaa ttccttccaa aataatggtc tttcgttgca
    52621 taagtgattg cggtacacat cgtttcccgt cctaaaacaa atcgttttta cacttttatc
    52681 ttacatctag tatttttttt atcaaaaaaa ggccaaagaa gattgattta ctagcattta
    52741 taaaaaatag tactcagggg gaatcaaaaa atattgtagg ttaaaagtac aacaataagg
    52801 ggctgtgaca aaagtcttgt cacagcccct tattccgaac aaacggtgtt caaaagcttg
    52861 catctgcggt aataagccca atcaaacgaa aaaataggaa aagctatttt tgtttggccg
    52921 ttcttattac ttgatgcagg acagcttctt cacaacctct aatcgttgat ataaggaagg
    52981 tacaggattt gaacctgcgc gccggtatta gccggttcgc cggatttcga gtccggtgca
    53041 ttaccactct gccaaccttc cgtaagtact atttttaaac ttttttcacg aaatgtcaag
    53101 cctatttcta atagataaat aacagaaatc gcttttttta gcaaaaaagt ccattgacag
    53161 tttgcagcca acggacttac cgatcaaatt catactgata gaacactatc tgattatttc
    53221 aggattatct aatgctaaaa tcgagtcaat tgtccgtttg atcagtgcaa tgatttgttc
    53281 ttctgttgga tgcatgatgt ttgatgacat caatgacgct aagccagtca ctgctaccca
    53341 tgtaccagta tgcagagcat cgacatattc atccgataat tgattgtatc tttcatcttc
    53401 tttaactatt tcacggaaat aattgtatga aaaatcatgc attttctttc cgtccccatg
    53461 ttcatcaatg tacaatgcca tgtaaagact atgatgcttt tttgcaaagt agatatagtt
    53521 caaaccgaga tcaatgattt tatcaccagt acgttcaata gggaaaacat cttcttttag
    53581 ttgttcaaag atagaatcca gcaacgtatt ttttaaatct tccatgtttt tgaattccag
    53641 ataaatcggc tgtgtcgaaa tccccatctt tttagcaata tttctcgcag taaatccttt
    53701 aaacccttcc tttgcaacaa catcataagc agcttttaga atttgatcct tggtatagac
    53761 ttttcttctc attaaaactc ccccacttct ttactgcagt atatgttgtt ttattgtacc
    53821 ctatttttag cattttttgc aaacatttta ctcaaaacgt tatattttaa attttttttc
    53881 agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca atgggttccc
    53941 ttacattttt agttttgacc taaataatag ttgtccaaat ctttcatttc aagttatagt
    54001 taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat ttatattcat
    54061 cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt tacaggtgtt
    54121 ttttttcttt ttattggctt gctttctaat actcctactg ataattggag tggattgcta
    54181 actattctta cctcgccaag caatcttttg acagattatt ttgctttagg cggtttcgga
    54241 agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc ttatcggcac
    54301 aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg tttctctttt
    54361 tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct atacgctgta
    54421 tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag cgcattatca
    54481 ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg tattttattg
    54541 gggaatttag ctggcatagc aattggtcta cttcttccgc ccttagctgc tcaaacttta
    54601 gttttccatc gtggattcac actttataat attggattca cctctgggtt gattgcgatg
    54661 acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac attggttttc
    54721 aatgaatatc actttcctct catttggatt atttttggct ttttttcgct gacagtcgga
    54781 attggtttct attataattc ctttcggctt ttggggattc gagaaatttt cgattcatct
    54841 ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt gatcaacata
    54901 ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca gttaaatgga
    54961 cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg tcatttaaaa
    55021 aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac ttttcatgag
    55081 atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtctcgc gcccataagc
    55141 ggtttttacg gcagttttta cggtgtaata gctggtgtac tacatattgc tcttgtccat
    55201 aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc aactggtttc
    55261 gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa ggaaaaaaag
    55321 acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt atttatattc
    55381 ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc ttttcataga
    55441 gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg atttgctgaa
    55501 caatcctcgg gaccctagta tggaaatcta ttatcaagaa ctattaggta atccccgaca
    55561 tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa tcatgtatgc
    55621 ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt attaacccta
    55681 ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga ttaaaatcta
    55741 ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata cacttcatct
    55801 gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc aaaccaactg
    55861 tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac atctccagcc
    55921 attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc ggtcacaagt
    55981 aagatttgat agccgtcttt atggacatgc cagtgattgc gacaacctgg ttcaaaagtt
    56041 acattaccta caccaacaga aacttcggga tcattcacta acatattcag atagctttac
    56101 ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat cacgccattg
    56161 tgtatttctt cgtgttttgt cgtcatttac gcctctttct tatcttcgct attttcttct
    56221 aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccatcc tacataaaaa
    56281 gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg cttgccaatc
    56341 ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga tatggtgatg
    56401 atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa taaaacatca
    56461 tcattcaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc tgcggtttgt
    56521 ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac tatggttcta
    56581 aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc tttcagcctg
    56641 tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa cgcttttttt
    56701 attcgccgat tgtaaaatta agctagacaa ctaaaaaagt catttgtgct acactcaaaa
    56761 tagttccgtc caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg
    56821 gatgaacttg taatgataga gtcttatttc aaaataaatc aatctgttgc gaaaactgcg
    56881 catttcttga atcgttcaag acaaacgatc cataaagtat acctgttctt caagcaagga
    56941 aaatcagcct tagagtacta tcaacagtat aagaaaaaca aatcaaactg tggtagacgc
    57001 ccgcttgttt tacctgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg
    57061 acacccgatg tgattgttgg tcgtgcagcg tttcctattc gttgttctgc tcgtaccatt
    57121 tatcgtatgt tcaaaaaggg gctatttaat ccttctgact taccgatgaa aggcaagcgt
    57181 aaaccaaatg gacatcaaga aagacgtgga aaacaagctt tccgtcgctc tattcatgaa
    57241 cgtgaaaaag attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc
    57301 gtaggtttga aacataaaag tgctgtaatt accttagttg agcgattatc aaaagttatc
    57361 atcacattga aaccgtgtgg tagacaagcg attgatattg aaaacaaatt aaatcattgg
    57421 tttgaatctg taccgaaaaa tctattcaaa tccatcactt ttgattgtgg aaaggaattt
    57481 tcaaattgga aacagatcag taatg
//
LOCUS       DAIGQM010000012        56736 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.012, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000012 DAIGQM010000000
VERSION     DAIGQM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.012"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            101..619
                     /locus_tag="NOA48_000658"
     CDS             101..619
                     /locus_tag="NOA48_000658"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0788946.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            747..1430
                     /locus_tag="NOA48_000659"
     CDS             747..1430
                     /locus_tag="NOA48_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCI0788947.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1739..1812
                     /locus_tag="NOA48_000660"
     tRNA            1739..1812
                     /locus_tag="NOA48_000660"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1773..1775,aa:Arg,seq:tct)
     gene            1971..2330
                     /locus_tag="NOA48_000661"
     CDS             1971..2330
                     /locus_tag="NOA48_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HCI0788948.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2453..4084
                     /locus_tag="NOA48_000662"
     CDS             2453..4084
                     /locus_tag="NOA48_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCI0788949.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4146..4787)
                     /locus_tag="NOA48_000663"
     CDS             complement(4146..4787)
                     /locus_tag="NOA48_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0788950.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4973..5049
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5069..5377
                     /gene="rplU"
                     /locus_tag="NOA48_000664"
     CDS             5069..5377
                     /gene="rplU"
                     /locus_tag="NOA48_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCI0788951.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5404..5748
                     /locus_tag="NOA48_000665"
     CDS             5404..5748
                     /locus_tag="NOA48_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCI0788952.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5761..6054
                     /gene="rpmA"
                     /locus_tag="NOA48_000666"
     CDS             5761..6054
                     /gene="rpmA"
                     /locus_tag="NOA48_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCI0788953.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6488..9295
                     /locus_tag="NOA48_000667"
     CDS             6488..9295
                     /locus_tag="NOA48_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0788954.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9486..9977
                     /locus_tag="NOA48_000668"
     CDS             9486..9977
                     /locus_tag="NOA48_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0788955.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10080..11069
                     /gene="manX"
                     /locus_tag="NOA48_000669"
     CDS             10080..11069
                     /gene="manX"
                     /locus_tag="NOA48_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCI0788956.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11102..11905
                     /locus_tag="NOA48_000670"
     CDS             11102..11905
                     /locus_tag="NOA48_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCI0788957.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11926..12840
                     /locus_tag="NOA48_000671"
     CDS             11926..12840
                     /locus_tag="NOA48_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCI0788958.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12923..13297
                     /locus_tag="NOA48_000672"
     CDS             12923..13297
                     /locus_tag="NOA48_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCI0788959.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13436..13681
                     /locus_tag="NOA48_000673"
     CDS             13436..13681
                     /locus_tag="NOA48_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0788960.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13853..14917
                     /locus_tag="NOA48_000674"
     CDS             13853..14917
                     /locus_tag="NOA48_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0788961.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15163..15588
                     /locus_tag="NOA48_000675"
     CDS             15163..15588
                     /locus_tag="NOA48_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0788962.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15581..16030
                     /gene="nusB"
                     /locus_tag="NOA48_000676"
     CDS             15581..16030
                     /gene="nusB"
                     /locus_tag="NOA48_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCI0788963.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16127..16981
                     /locus_tag="NOA48_000677"
     CDS             16127..16981
                     /locus_tag="NOA48_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCI0788964.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16982..18319
                     /locus_tag="NOA48_000678"
     CDS             16982..18319
                     /locus_tag="NOA48_000678"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCI0788965.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18324..18548
                     /locus_tag="NOA48_000679"
     CDS             18324..18548
                     /locus_tag="NOA48_000679"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCI0788966.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18550..19440
                     /locus_tag="NOA48_000680"
     CDS             18550..19440
                     /locus_tag="NOA48_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0788967.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19449..20267
                     /locus_tag="NOA48_000681"
     CDS             19449..20267
                     /locus_tag="NOA48_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCI0788968.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVTVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20374..20823
                     /locus_tag="NOA48_000682"
     CDS             20374..20823
                     /locus_tag="NOA48_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0788969.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20841..22523
                     /gene="recN"
                     /locus_tag="NOA48_000683"
     CDS             20841..22523
                     /gene="recN"
                     /locus_tag="NOA48_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCI0788970.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22578..22694)
                     /locus_tag="NOA48_000684"
     CDS             complement(22578..22694)
                     /locus_tag="NOA48_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCI0788971.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22767..23723)
                     /locus_tag="NOA48_000685"
     CDS             complement(22767..23723)
                     /locus_tag="NOA48_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0788972.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23894..24262
                     /locus_tag="NOA48_000686"
     CDS             23894..24262
                     /locus_tag="NOA48_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCI0788973.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24432..24863
                     /gene="mraZ"
                     /locus_tag="NOA48_000687"
     CDS             24432..24863
                     /gene="mraZ"
                     /locus_tag="NOA48_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCI0788974.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24884..25843
                     /gene="rsmH"
                     /locus_tag="NOA48_000688"
     CDS             24884..25843
                     /gene="rsmH"
                     /locus_tag="NOA48_000688"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCI0788975.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25848..26249
                     /gene="ftsL"
                     /locus_tag="NOA48_000689"
     CDS             25848..26249
                     /gene="ftsL"
                     /locus_tag="NOA48_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI0788976.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26250..28442
                     /locus_tag="NOA48_000690"
     CDS             26250..28442
                     /locus_tag="NOA48_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0788977.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28468..29430
                     /locus_tag="NOA48_000691"
     CDS             28468..29430
                     /locus_tag="NOA48_000691"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCI0788978.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29444..30805
                     /locus_tag="NOA48_000692"
     CDS             29444..30805
                     /locus_tag="NOA48_000692"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCI0788979.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30831..31919
                     /gene="murG"
                     /locus_tag="NOA48_000693"
     CDS             30831..31919
                     /gene="murG"
                     /locus_tag="NOA48_000693"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCI0788980.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31934..33154
                     /locus_tag="NOA48_000694"
     CDS             31934..33154
                     /locus_tag="NOA48_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCI0788981.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33310..34635
                     /gene="ftsA"
                     /locus_tag="NOA48_000695"
     CDS             33310..34635
                     /gene="ftsA"
                     /locus_tag="NOA48_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCI0788982.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34658..35899
                     /gene="ftsZ"
                     /locus_tag="NOA48_000696"
     CDS             34658..35899
                     /gene="ftsZ"
                     /locus_tag="NOA48_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCI0788983.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35916..36593
                     /locus_tag="NOA48_000697"
     CDS             35916..36593
                     /locus_tag="NOA48_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCI0788984.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36607..37206
                     /locus_tag="NOA48_000698"
     CDS             36607..37206
                     /locus_tag="NOA48_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCI0788985.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37221..37508
                     /locus_tag="NOA48_000699"
     CDS             37221..37508
                     /locus_tag="NOA48_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCI0788986.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37557..38339
                     /locus_tag="NOA48_000700"
     CDS             37557..38339
                     /locus_tag="NOA48_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCI0788987.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38360..39067
                     /locus_tag="NOA48_000701"
     CDS             38360..39067
                     /locus_tag="NOA48_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCI0788988.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39329..42127
                     /gene="ileS"
                     /locus_tag="NOA48_000702"
     CDS             39329..42127
                     /gene="ileS"
                     /locus_tag="NOA48_000702"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCI0788989.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42176..43702)
                     /locus_tag="NOA48_000703"
     CDS             complement(42176..43702)
                     /locus_tag="NOA48_000703"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCI0788990.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43717..44364)
                     /locus_tag="NOA48_000704"
     CDS             complement(43717..44364)
                     /locus_tag="NOA48_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCI0788991.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44548..44877)
                     /locus_tag="NOA48_000705"
     CDS             complement(44548..44877)
                     /locus_tag="NOA48_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCI0788992.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45054..45782
                     /gene="sfsA"
                     /locus_tag="NOA48_000706"
     CDS             45054..45782
                     /gene="sfsA"
                     /locus_tag="NOA48_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCI0788993.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45798..46811
                     /locus_tag="NOA48_000707"
     CDS             45798..46811
                     /locus_tag="NOA48_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0788994.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46811..48088
                     /locus_tag="NOA48_000708"
     CDS             46811..48088
                     /locus_tag="NOA48_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0788995.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48151..50853
                     /locus_tag="NOA48_000709"
     CDS             48151..50853
                     /locus_tag="NOA48_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0788996.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51005..51322
                     /locus_tag="NOA48_000710"
     CDS             51005..51322
                     /locus_tag="NOA48_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0788997.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51352..51672
                     /locus_tag="NOA48_000711"
     CDS             51352..51672
                     /locus_tag="NOA48_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0788998.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51780..53240
                     /locus_tag="NOA48_000712"
     CDS             51780..53240
                     /locus_tag="NOA48_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0788999.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53308..53529
                     /locus_tag="NOA48_000713"
     CDS             53308..53529
                     /locus_tag="NOA48_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789000.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53560..53742
                     /locus_tag="NOA48_000714"
     CDS             53560..53742
                     /locus_tag="NOA48_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCI0789001.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53742..54155
                     /locus_tag="NOA48_000715"
     CDS             53742..54155
                     /locus_tag="NOA48_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCI0789002.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54278..55459
                     /locus_tag="NOA48_000716"
     CDS             54278..55459
                     /locus_tag="NOA48_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789003.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55530..55694)
                     /locus_tag="NOA48_000717"
     CDS             complement(55530..55694)
                     /locus_tag="NOA48_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789004.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55848..55921
                     /locus_tag="NOA48_000718"
     tRNA            55848..55921
                     /locus_tag="NOA48_000718"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55882..55884,aa:Arg,seq:cct)
     gene            complement(55990..>56736)
                     /locus_tag="NOA48_000719"
     CDS             complement(55990..>56736)
                     /locus_tag="NOA48_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789005.1"
                     /translation="HIRASLKDAVEEGLIPFDPTRKAVIKGKDSLKPKEDKYLDYDQF
                     KSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDIDFEDQIITINKTWNYK
                     LNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVKNPHNFVFFNLKNGLV
                     SSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNILSVSKRLGHSSLETTM
                     STYLHIVRELEDQDKEKINAVFDSLYKNDN"
BASE COUNT        18734 a         9579 c        12177 g        16246 t
ORIGIN      
        1 ataattatta aagggaaaca tttttacagc tataatttga aaaaaattta tcgttattat
       61 atgattaaga aggattgaat aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat
      121 aacttttata agttctataa cgttgattat atttttaatt cttattcttc tcgtcgtctt
      181 ggttccccga atttttggtt tgactcctta tattattgag gacaaagaaa tgagtccata
      241 ttatgcacaa ggaaatctga tatatgtacg accgaaaaat acaaatgaga ttttagtcgg
      301 agatattatt acatattatg aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc
      361 cgttgaaaac aaccacgaag atttttatac aaaagctgat acaaagactt atattgagcc
      421 tggagtagta aaaaagagaa atattatcgg tagtcccatc tttcagattc catatattgg
      481 actagtcctt tcaaaaacgg catttgcatg gattcagggg ttattcttta cgattgcttt
      541 ttgcctaaca ggaatcacag catggaatac ctttgtagag ttgaaaaaga agcggagacg
      601 aacacagaaa tttttgtaag aatgttaaaa acataaatgt attccagaga tccaacgact
      661 cttctgaaca tgaaacacga gaaaacactc atgcagcttg tagatttagt cagttgttcg
      721 tataatgtgt gaagaggagg agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca
      781 aagaagaact attggatttt atgcgtaccc agcaaaaaaa attaccgggt gagctaggca
      841 aactggaaga agaagctcat gtagcagaag taccagttat tccccatgaa acagttgtat
      901 ttttgaaatt tttacttgga cagcttcagc ctgaacgaat cttggagatc ggagcagcta
      961 tcggtttttc atcaagtgtc atggccacga caatcggaga aaacgctcat gttacgacaa
     1021 ttgatcgttt cgatgtcatg atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga
     1081 cagataaagt gactttgctt gaaggtcaag cagcagatat cttgccggag ttgtctggtc
     1141 cgtatgactt tatttttatg gatagtgcaa aatcaaaata tattgaattt ttacctgaat
     1201 gcttacgttt gttaagaaaa ggtggcgttt tgatggtaga tgacatcttc caaggaggaa
     1261 cgatcttgct cccagatgaa gagattcccc gtggcaaacg agctatccat cgtaaattaa
     1321 atgaatttct tcgtgttgtg atggatcatc ccgatttgac atcgacaatc ttgccattag
     1381 gtgatggtgt gatcttaatg acaaaggaat cagaaacaat cgagttgtga tacatgatta
     1441 tggcagcctg tagataatcg attgaatcga gggctcaatt cgaacttgat gtaaaagttt
     1501 ctatatttgt aagtcaatta aaggatacag gaaatctaaa taaacaggag tagcatgaag
     1561 tcaatgtagc tcctgttttc aattgataac cttagaacag ctgaaggaga atgtctcgtt
     1621 ttaaaagatt gatttagtag ttgggccaaa ataattcatt atttgctaat taaataacta
     1681 tttcgtattg acagaagcaa tttaattatc tataattatt gatgttccgc tgattcttgt
     1741 catagtagct cagctggata gagcatccgc cttctaagcg gacggtcggg ggttcgaatc
     1801 cctcctgtga cgctaaaaaa ccgttagaaa ctgaggtttc taacggtttt tctttgtttt
     1861 ttgtgccaat attgtttgtt ttcaaaggca aataaaataa aaaaacatcc ttatcgagta
     1921 caattataag gagcaaaaaa ataaaactca tcagaaaaga ggaagaagat atgacgatac
     1981 tatctagaat tttagtgact ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa
     2041 cggtgagaac tgattctgac acgacaagta gggtttttaa aatgagtaaa gaagagttaa
     2101 gcagaaaatc tgttcaaaca ttgtttaaga accaaggagt gtacaatgga ctattaggag
     2161 tgggactact ttatggagct tatctttctt ccgcatctaa agaaatcaca agtatgctat
     2221 taatatctat tttttttgtt gcattatatg gcagtttgac tagcgatcgt tggattttac
     2281 tcaaacaagg tgggctagct ctgttggcat tgctttctat tttcttataa atatagaaaa
     2341 aataagaatt tatctaacag gaaactttgt gaaaaatatt actttatctc atgaaatatg
     2401 atattctaat gaatggtatt ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa
     2461 aaattatgtt tcctcactaa aaaaagaatt ttcaggttat gatctttcaa gatttcagaa
     2521 agatcttttg gctgggatca cagtagctgc tgtagcattg cctttagcct tggcttttgg
     2581 ggtatcaagc ggagctgatg cggccgcagg tttgattacg gctatcattg ccggtatcgt
     2641 tattggcggt ttatcaggcg gtttttatca aatatcaggt ccgacaggtg cgatggcagc
     2701 tatcttgatg tctattgcgg caacaaaggg aatgcaaggt gtattgcttg ctactttttt
     2761 agcgggtcta tttttacttg cagcaggact tttccgatta ggaacactga cttcttttat
     2821 cccagcaccc gtaattacgg ggtttacttc aggtattgct atcattattg cattaggtca
     2881 gatcgataat ttatttggtg ttcactcgga aggtacaaac gttattgaaa aactaagtag
     2941 ttatcaaacg ataggatttc cgataaacac agcctctttg atcatgggag ggctagtcat
     3001 tttagggatg tttatctatc caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc
     3061 tatcattttg gcaacagcag ttatgctatt gttccattta ccagtagcaa ctgtgggtaa
     3121 gattccacaa acattgatca gtagtaatcg tttgaatatg ggagatttta gcttttctgc
     3181 cttgcaacaa gtggcagttc cagctattag cattgcttta ttaggaatga ttgaaagctt
     3241 gctatgtggt gcttcggctg gccgaatggc aaataagccc ttagatagca atcaagaatt
     3301 aatggcgcaa ggaattggaa atctgttgct tcctttcttt ggcgggattc ctgctactgc
     3361 ggccatcgcc cgtacaagcg tggccatcaa atctggtgca caaactagat tagctggtat
     3421 gatacatgca gttgtcttac tgctctccat gcttgttttt gcgccagtga tgtcacagat
     3481 tccaatgcca gcacttgcag gtgttttgat tgtgacggct tggcgtatga atgaatggga
     3541 aacgatcaag gagctattta ctaataaata ttggtcagca gttctattgt ttatccttac
     3601 gatgatttgt acagttatct ttgatttaag tattgctatc gtgatcgggg tgatcggcgg
     3661 ctgtgtattt tttgttgtca aaagcgctgc tatcacgatt tcattagaaa cgatcgattg
     3721 gcaaagaatg gggctgccag aaacggaaaa gctgaataac tggacagtag tgtatattag
     3781 tggtccactg ttttttatgt cttcagaaaa actcaaaaat aaattggaag aactaaatca
     3841 tcacgatggt gtcattttct ccatgcgagg cgtaccaagt attgatttga cggcacgtgc
     3901 agtttttgat gaatttcaag aaaaagcaga gcaaagagga caaacgatta tctatacttc
     3961 cttgcagcca gaagtagaaa aacaactttc tcacttgtgg gaacatacat tcacgcatca
     4021 acatcaaaca gttgctcatg cgttgacagc tttacatgcg aaatatactg caattagcca
     4081 ttaaaacaat gaaaaagaac agacaagact gtaaactgaa gattttatgg tcttgtctgt
     4141 tctttttaat attgctgtaa aagtgaagct agtacttgcc agtcttgatg gataacaggt
     4201 acaagggagc gattgtagaa aatagctgct ggatgaaaaa gtggaagaat tcgatagttt
     4261 ttttctgacc attcgtaggc atccttttgt tctgttaatt gtaagacagg ccctgtatag
     4321 agttgaccat gatttttggt aaccgtatat tctttgccaa gtaaacgttg aagaccaatg
     4381 tttccaagtg tcgcaattaa ttttggctgg accttcatca gttcgtaatc caatattggt
     4441 gcatgcgcaa atacttcgga acgagtaggt gtccgatttg gataaacagt ttctgactgt
     4501 tgtgtccgtt tattgatccg atgagtcacg cgatacgggc ggctccttac agcactggtg
     4561 atatacacct cttctcgtgt taagccagtt gaagaaagtg cctgcatcaa ttcttttcca
     4621 gcttgaccgc taaaaggaac atgcgtatca atctctgttt tccctggggc ttctcccacg
     4681 agcatcagtt taggatgaag aggtccttgc ccagcgataa atccttctac aggacggccg
     4741 ttcattctta aagaagcttc ttgtatcagt tcttttgggt attccattta tgctcctcct
     4801 ttttctttta ttataagaat aaaagaaaca caatgcgact attttatttg gtagaactgt
     4861 gaggatagaa aagcagaagt attgcttgaa tttttgtttt actttttgat tttaaattta
     4921 gttgactaac ggttgctgtt ctggtaagct agtactgttg taattgtgga ctccacagct
     4981 acaaccgctc agaacaagta ataagcacag catatgctgt cacttcggat ggcgagtcta
     5041 agtatatcag aaggaggtgc tttatagcat gtacgcaatt attaaaactg gtggtaaaca
     5101 agtaaaagtt gaagtgggac aagcaatcta tgttgaaaaa cttgacgttg aagcaggaga
     5161 aaaagttgtt tttgacgaag ttatcttagt aggcggagaa tctacaaaag taggcgctcc
     5221 aactgttgca ggtgcaactg ttgaaggtac tgttgaaaaa cacggcaaac aaaagaaagt
     5281 cgttactttc aaatacaaac ctaaaaaaca ttcacaccgt aaacaaggtc atcgtcaacc
     5341 atatacaaaa gtggttatcg acgcgatcaa cgcttaatag cgtttgagaa agaaggccta
     5401 tatatgatca aaggaacatt taagcgaaat gacgcaggtc agatcgtttc attcactttg
     5461 accgggcatg ctgatgctgg tccttatgga agtgatatcg tttgtgcggg tgtttctgcg
     5521 ttagcgatca gcactgtcaa cgggattgcc tcattagccg gttttgagcc gattgttgaa
     5581 atgaatgaag aagaaggcgg ttatctttat accgaagtca cttcaggaat gacacaagaa
     5641 caaaacaata ttgctgagat tctattagaa aatcttttat taggattaca atcgatagaa
     5701 gctgaaaact cagaatatat ccaaattaaa acaattaatg ataaatagga ggtgcagacc
     5761 atgttgttat ctatgaatct acaattattt gcccacaaaa aaggtggcgg ttctacatct
     5821 aacggccgtg actcagaatc aaaacgtcta ggtgctaaac gtgctgatgg acaaacagtt
     5881 acaggtggat caattcttta ccgtcaacgc ggtacaaaaa tctatccagg tgtaaacgtg
     5941 ggtatcggtg gagacgacac tttatttgca aaagttgatg gcgtagtacg tttcgaacgt
     6001 aaaggccgta acaaaaaaca agtgtctgtt tatccagtag ctcaagaagc ttaattgaat
     6061 cttatgatta aagaggttgt gacaagactt ttgtcacagc cttttttgtt tataaaaata
     6121 aaagttgtag tggaggctac gaagtttact ttgtcttttt acacttaata tttttttgcc
     6181 aatttggaat caggatgttt tgataactat cgttttcaat tgatggaagc tatattgttt
     6241 gctatcagtg aaataattat atggtaaaca gtgttctttt tcttgtttcc attataaaaa
     6301 tcgtatcggg atttttcgtt cttttaaatt gaacatttct atctatccgc gtgttatcaa
     6361 caaaacaaaa tcaggtaaat agttgacgaa acagaaataa atacatagta ttatgttttg
     6421 aagcctaagt acaatagtct atagaaaagg agcgatacca ttggcaaaac gcattgaccg
     6481 aatttatatg tatgtcaaag aaaaaaccgc tcatttaaca aaggcagaat atgatcaagg
     6541 agtaacaaca caggaaattg ctgaagtgtt agggattcag cgaacaaata gcagtaaaga
     6601 tctgaatcag ctagtgcgcg aaggaaaact gataaagaca gacggacgac cagtacgtta
     6661 catatatcaa acactcgtta cgcacgtaaa gccagttaca aaacatgtag tcagttacaa
     6721 agaaacgccg gtctctgaag aaaaaaatac actccaaata gatactaagg atatctttgc
     6781 aaaaatcatt ggagctaacg gcagcatgaa aaattcagtg gaacaggcaa aagctgcgat
     6841 tttgtatccg ccaagaggat taaattgttt gattacagga cctaccggat caggaaagac
     6901 ttattttgca cacgcgatgt atcattttgc aaaagcgcat catgtaatag atgaggaaac
     6961 ggaactgatt gttttcaatt gtgctgatta tgccaataac cctgagcttt tgatgagtca
     7021 tttatttggg tacgcaaaag gtgcttttac aggcgcagat gaagaaaaaa tggggattat
     7081 cgatcaagcg gatggcggta tgctgttttt ggatgagatt caccggttgc cgcctgaagg
     7141 tcaagaaatg atcttttact ttatggatca tggaacttac agtcgtcttg gggaaacaac
     7201 gaaatcccat gaagcaaatg tacggatcgt aggtgcgacc acagaagacc caggttcttc
     7261 tctattagaa acttttgttc ggcgtatccc aatcaatatc aaacttccgg cttttgaaaa
     7321 acgtcctgca aatgagaaag tcgatttagt aaaaatcatg attgcccacg aagcaaaccg
     7381 cacgcagcga aagatttctt tgacagaaga tgtagcaaaa gcattgatcg gcagtgtgac
     7441 ctatggaaat ataggacaat tgaagtcaaa tatccagtta gtatgtgcac gaggatttct
     7501 aaatcatatg caatcacccg aaatctcgat cacaatcgat gatttgacag aagggattcg
     7561 tagcggattg attcaattag caagcaaccg cagtgcaatg gcagagcttt ctaaaatatt
     7621 ggagccaaag ataactgtag caccaaatga tacgatcatg aaaatccaat cggactccta
     7681 tgagttacct tataatctat atgatatcat cggagataaa gcagctttac tgaagtcgga
     7741 tggtttggat caagaagcaa tcaatcattt catttctaca gatatcaaca tccatctgaa
     7801 gtctttctat aaagaccatg gtttttcttt taatgcagac agcaaattag cagaatttgt
     7861 agatccgaaa atcatagaag tgaccaatca gatttatgta atggtcaaaa gatctttacc
     7921 atatgagttt cagcaaaact ttatttatgc tatgagcttg catatcagtt cttttttgaa
     7981 aaaaatcaac ttaggagaag aacggcatac gaatgataac atccgtgaga tggcttttga
     8041 ttttccagat gaatatgctg ttgcgaaaga agtgcgtagt tatatcgaaa cgtattttca
     8101 agtggagatt ccagaaagtg aagactatta cttgaccgtt ctactcgtct cgttacgggc
     8161 aaatcaagca agcggcagaa tcggtgtagt cgttgcagct cacggaaaca gcacagcaag
     8221 cagtatggtc caagttgtcc aacagttgtt agatgcagag aacgtacgag cagtagacat
     8281 gcctttggat atggatccga aaacagcatt ggaccgaatt gaacgcaatg tacaagaagt
     8341 agatgaagga agcggggtca tactcttagt agatatgggg tcccttgcgt cgtttaattc
     8401 gcaaattcaa agagacactg gaattccagt acgtactgtt gatatggtaa caacttctct
     8461 agttttggaa actgtacgaa aggtctcagt attagggaca gatctagata tgttgcatga
     8521 atcattgaaa aattttcgag gttacgcaga aatatcttct gtagaatctg ttcaggaagc
     8581 aaaacctatt cataagaaaa aagctgtttt ggctatctgc gcatctggcg aaggtacagc
     8641 acaaagaatc aaagaattga tcgaacgagc ggtaaacaag cgtcaagaaa cagaattaga
     8701 agttctagct ttgtcgattg tggaagtgaa agaagaactg ccagttatcc aaaaagaata
     8761 tcagatcata gctactactg ggattactga tttgaatatc caagccccat ttattccttt
     8821 agaacgtttt attgatcaaa atatcgaagt cattttggat cagttgctga tggaatcaga
     8881 attggaggaa actgaattca tctccctaga tgaagagtca gctaaaaata cgtgtgttga
     8941 gtttatctct gataacttca tctttattaa tggtagtaag ttaatcgatc caatgtggca
     9001 attttctaca caaatctctc agacgacggg aatcggcgat gaagaatatg gattcaaaat
     9061 caacctagtg atgcacacag caggaatgat cgaacgtatt attcggaatg aaccattgac
     9121 tgtggaagaa aacgaattga caaatacaac gaatgatcct ctttatagcc aattggcagc
     9181 ctcagttgtt ctgttggaag atcagataaa agtaaaagtg ccgatagaag aaatgtatta
     9241 tctgctacgt ctagtccata atcagttaga taaaaaagaa tacactgtgc catgaataca
     9301 caaaaacgat acacttttat agtgtatcgt ttttgtgtat tggttaagaa tcctttaaat
     9361 tcaattagtg tatcgtaaaa aagttggcac gctttttgct tatagtagtg tgtgctagga
     9421 ggtggttgtt cacacagaaa tgataggggt ttctgtgaag tagtgaggaa gaaggagttt
     9481 tgcagatgga tattcgattg gcacgtatag atgatcgttt aatccacggg caagtcgcaa
     9541 cagtttggtc gaagcaaaca ggtgttgaac gtatcattgt gatcagcgat gtagtcgctc
     9601 aagataaatt gagaaagttt ctactaaaag aagctgcacc gccggggatc acagcaaatg
     9661 taataaccgt gcagaaaatg attcaaatct atcatagtgg attattatca cgagcaaaag
     9721 tgatgctttt attcaccaat ccccaagatg ttgaagcggt tgtccgctgc ggtgtacagt
     9781 tgaagtcgtt gaatatcggc ggtatgagtt ttactgaagg caaatcaatg attaccaatt
     9841 ttgtttcagt aaatcaacaa gatattgatt cctttcgtta cttgaacagt caagaagtgg
     9901 agttagagat tcgaaaagta cctgctgaca ggaaaatcct tttgatggaa ctactagcga
     9961 aaatcaaaaa ggtgtagcaa gaatggttgt tggaaaaggt caaataattc tgttgtaatg
    10021 gttagcaatt attaatattt ttgaatttgt tacaacaaaa gtaaatagga ggtataaata
    10081 tggtagggat tatcctagca agtcatggac aatttgctga aggaatctta caatccggtt
    10141 caatgatctt tggcgaacaa gaaaacgtca aagccgtgat tttgaaacca agtgaaggtc
    10201 cagatgactt gagagccaaa ttggaagaag cggttgcttc ttttgataat caagacgaag
    10261 tgttattctt agttgattta tggggcggaa caccgttcaa tcaatcaaac acattattcg
    10321 aagagcacaa agataaatgg gcaatcgtca gcggtttgaa tttaccaatg ttgattgaag
    10381 cctacgcatc acgcttttca atggaatctg ctcatgaaat tgcagcacac atcattgaaa
    10441 cagcaaaaga cggtgtaaaa gtaaaaccgg aagaattaga accggcagaa gcaccgaaag
    10501 cagcagttga agacgcacaa cctaaaggag cacttccaga aggaactgtg gtcggagacg
    10561 gaaaaatcaa atatgtatta gcacgtgttg actcacgtct gttacatgga caagttgcga
    10621 cagcttggac aaaagcagtg caaccaaacc gtattatcgt tgtttcagat gcagtatcaa
    10681 aggatgatct gcgtaagaga ctaatcgaac aagctgctcc tccaggtgta aaagcaaatg
    10741 ttattcctat tagcaaaatg atcgaagtag caaaagaccc tcgttttgga aataccaaag
    10801 cattgctttt atttgaaaat cctgaagacg tattgacagc tgttgaaggt ggcgtagaca
    10861 tcaaagaatt aaatgttggg tcaatggcgc attcggtcgg taaagtcgtt gtaagtaaag
    10921 tattgtctat gggacaagaa gacgttgaag cgtttgagaa gcttgaacaa aaaggtgtga
    10981 aattcgatgt acgtaaagta cctaatgatt cacgcgataa catggatgat attttgaaaa
    11041 aagcaaaagc tgaattagca aaagcgtaat aaataatatt aaaatttata ggaggcttat
    11101 catgtctatt atttcaataa ttttagtcgt attagttgcc tttctagctg gtatggaagg
    11161 tattcttgat gaatttcaat ttcatcaacc actagtggca tgtacattga tcggtttagt
    11221 taccggtaac ctcgaagctg gtatcgtact tggcggtacg cttcagatga tcgctttagg
    11281 ttgggcaaat atcggtgccg ctgtagcacc agatgctgca ttagcatcag tagcatcagc
    11341 aattatttta gttttaggtg gacaaggtgt taaaggtgtt ccttctgcga tcgcgattgc
    11401 cgttcctttg gctgttgcag ggttgttctt aacaatgatc gtacgtacaa tcgctgttcc
    11461 aatcgttcat ttgatggatg cggctgctga agaaggaaac atccgtaagg ttgaaatgtg
    11521 gcacatcatt gctgtatgtt tacaaggggt tcgtatcgcg gtcccagcag cagcgttgct
    11581 atttatccca gcacaaactg tgcaatcatt ccttgaatca atgccagcat ggttaacaga
    11641 tggtatggct atcggtgggg gaatggtcgt agctgtaggt tacgctttgg taatcaacat
    11701 gatggctaca aaagaagtat ggccattctt cgttattggt ttcgttgtag ctgcaatttc
    11761 tcaattaaca ttgattgctc taggtgcttt aggtgttgca ttagctctta tttacttgaa
    11821 cctttctaaa atgggtggtt catcaaataa tggaggcgga agcaactctg gtgacccttt
    11881 aggcgacatt ttgaatgact attaatcttg aaggaggaaa ataaaatggc agaagaaaaa
    11941 atcaaattat caaaaaaaga tcgtttagct gttgcgtggc gctctacctt cattcaaggt
    12001 tcatggaact acgaacgtat gcaaaacggt ggctgggcat tttctatgat tccagcaatc
    12061 aaaaaattat acaaaacaaa agaagaacgt tctgcagcat taaaacgtca cttggaattc
    12121 tttaatacac acccatacat tgcttctcca attttagggg ttacattggc tctggaagaa
    12181 gaacgtgcga atggcgcgcc tgttgatgat gtagcgattc aaggggttaa agtaggtatg
    12241 atgggtcctt tagctggtgt tggtgaccca gtgttctggt ttacagtacg tccaatgcta
    12301 ggtgcactag gtgcttcatt agctatggga ggaaatatcc ttggaccaat catcttcttc
    12361 ttaggttgga acattattcg ttgggcattc atgtggtata cacaagaatt tggctacaaa
    12421 gctggttcta aaattactga tgacctttct ggcggattgt tacaagacgt aacaaaaggt
    12481 gcttcaattt tagggatgtt cgtattagct gcccttgtac aaagatgggt atcaatcaaa
    12541 ttcttaccag ttgtatcaac tgtaaaatta gataaaggtg cttacatcga atgggataaa
    12601 ttgccttcag gtggtgaagg aatcaagagt gcatttgaac aagttaataa tggcttagcc
    12661 ctttctcctg aaaaggtaac aacattacaa gacaacttag accaattgat tcctggttta
    12721 gctgcattag gattaacatt gttatgtatg tggttgctta agaaaaaggt ttctccaatc
    12781 gttatcatcc ttggtttatt cgtagtcggt gttgttggac acgtcatcgg acttttataa
    12841 tccataaaaa tatagctcgg gcgttgtccc gagctttttt tatatagtat actgttcata
    12901 aacaaatatc tggagggaga aaatggttca atcaatcaat acaaaagtag acttggtaat
    12961 tgatgctact tcgtttacgg gtctgacaga ttacgggcaa atcatgatag gtgataatgg
    13021 ttttgagttt taccatgcgc gagatagacg caaatatatc caaattccat gggaagaagt
    13081 ggattatgta ctagcatcag tcatgctaaa gggaaaatgg attcctcgat atgccattca
    13141 aacgaaaaaa aatggtacat acacattttc ttccaaagaa cctaaaaaag tgcttcgtgc
    13201 gatcagagaa tatgtagatg aagatagaat ggtacaatca ttgagtttct ttgatgtagt
    13261 gaaacgtggt attcgtagta tgtttaaacg caagtaaaaa ataaagaaaa cttctaagag
    13321 gaggttttct ttattttttt actttgcaga agaaaatatg aaatagcaaa accaattatt
    13381 tgtccccttt aaatcccata tgctaaaatt gattagcaaa gaaggaggtt atattatgag
    13441 ttggttatgg acattgattg ttggagccgt gatcggagca attgcaggtg cgatcaccag
    13501 taaaggaaat tcgatgggct gtgtaacgaa tatcattgct ggactagtcg gttcaagtat
    13561 tggacaagcg attttcggcg aatggggacc aaaagctgca ggtatggcac ttattccatc
    13621 tattttaggc gcagtgattt tggtagcagt tgtctcattt ttctttggaa aacgatcata
    13681 agtttttaca aaatagtaaa ctaaaaggag ttgcagcgag actgtgactc ctttttggct
    13741 ttatttattt aaaataaaaa gaagttttcc ggaaattttt atttaactgt cgtgtacgaa
    13801 gaaaagtttg ctataatgga aaaaagcgtg caaagaaaga gggagtttca ttatgatgct
    13861 acgtgtagaa aaattgcgca aaaaaatgca agaagaaaat ttggattcat ttttggttac
    13921 cagtccgtac aatcttcgtt acttaacgaa ctttacaggt acgacaggat tagctgttat
    13981 tactttggaa aaagcatttt ttattactga ttttcgttat accgagcagg cggcagcgca
    14041 ggctcaaggg tttgaaatta ttaaaaatgt cggacctatt tttgatgagg tagcaaactt
    14101 agtacgcaaa gaagaactgc actcattagc ttttgaggaa acaacagtct catttttaga
    14161 atattcggtt ttagaagaaa tcatcgatgc ggaattagta cctgtttcac agatgatcga
    14221 agaactcaga gaagtgaaag atgaagaaga aatcgctatt atcgaaaaag catgtcatat
    14281 tgcggatatg gcatatgatc acatcctgaa aatgatccaa ccgggcatga ctgagattga
    14341 agtcgcaaat caactagact tttatatgcg ttctcttggc gcttcaggtg tttcttttga
    14401 tacgatcgtt gctagcggat tgcgttcggc tatgccgcat ggtgtagcaa gcaaaaaaat
    14461 catcgaacaa ggtgacttga tcacattgga ctttggttgc tattacgaag ggtacgtttc
    14521 cgatatgaca cgtacattcg ctattggtga tcctggggaa aaattaaaag aaatttatca
    14581 aatagtctta gatgctcaat tagcagttat tgatgctgca aaaccaggaa tgactggtgt
    14641 ccaattagat gcagttgcta gagattatat ttcaaaacat ggttacgggg aagcatttgg
    14701 acattctaca ggacatggga tcggtttaga gatccacgaa ggaccaaacg tttcttctcg
    14761 tgcagaaaag caatttgtac caggaaatgt gatcactgat gaaccaggga tctacttacc
    14821 aggaatcggt ggagtacgta ttgaggatga cttgttgatc acagaagatg gaaatcgtgt
    14881 gttgactcgt tcaccaaaag aattgatcat cttatagttt catcaataga agaagtaagc
    14941 gtaaaaatca gtgttcacag actttgttat agaaaatcac tcgatttaat gatacactat
    15001 agaagaactt ttaagctgta agagataata aagttgggtg ttttctccaa ttcatagcag
    15061 tttgcagctg atcggcggca gttttcttac cacgtgatca ctatgccgca tcatagagaa
    15121 ttcggatgta tctcgtgctt aggcaaaggg aggaataaat aaatggcaga tgaaaaaaat
    15181 ttgattttaa acgcaaacca agatttagga gagatcgtga tcgctcctga agtcatcgaa
    15241 gtaattatcg ggattgcagc ttctaaagta gaaggcgtat acggaatgcg cggaactttt
    15301 gccagcaatg tcactgaatt attaggacgt gcagctcacg gaaaaggtgt ttacttagca
    15361 aacgaggaag atggcttgaa agtagatctt tactgttatc tagaatatgg tgtttcagtt
    15421 cctaaagtag caatggaaat gcaggaacgg gtcagccagc aagtcctttt catgacggat
    15481 atcgatttat ctgaagtcaa tatccatgta gtagctgttg ttcctgaaaa attagaacaa
    15541 ccaacaatcg aagaactttt tgaagacgaa gaggaagaga atgaataaag aattatcaag
    15601 acacgagatt cgggaaatgg cattgcaggc tttatttcca ttagacttca atgcagacct
    15661 aacaaaagaa gatgcgattt tcaacgcaat cgaattagac caccgcgaca tgatcaacga
    15721 agatgaatca gagtttgttc ctgtttatct tgatacgcta gttggcggtg tctgtgcaaa
    15781 aaaagatgaa ttggataaag tgattgaaaa acatttaaaa aacaattggc acatcaatcg
    15841 gatctcaaaa atggatttgg tgatcttgcg tatcgcgatt tttgaaatga cttatgtgac
    15901 agatgtacca gcggctgttg ctttaaatga agcaatcgag ttggcaaaaa catttagtga
    15961 tgaccgttca cgtaaattcg tcaacggtgt tttatccaat gtattgaaag aattagaagc
    16021 tggggcgtaa gtcctagctt ttttctatga atcatcataa acctgttata aatcgggaaa
    16081 attctatggt agaatgaaaa cacaaaaaat atctgggagt ggttagatgg cagaattgat
    16141 taacggaaaa gaattagctg aaaaaatgca ggcagagatt gctgaaaaaa tccaaaaatt
    16201 gaaagataat ggtatccatc ccggattagt cgttttattg gtaggggaaa atccagccag
    16261 ccaaatctat gtaagaaata aagaacgtgt agcaaaagaa atcggaatcc attcattggt
    16321 agagcgttat cctgagacga tttctgaaga cgaactactt gcagaaattg aaaaatacaa
    16381 tcaagatcct agttttcatg gtatattggt ccaattacca ttgccaaagc atatagatga
    16441 agaaaagatc ctgttagcta tccgccctga aaaagacgta gacggttttc atccgatgaa
    16501 tttaggcaga ctccttgcgg gtaaaccgga caagattcct tgtactccat acggcatcat
    16561 gaaaatgttt gaagcttatt ctatcgatcc ggcgggtaaa cgagcagtag ttatcggacg
    16621 aagcaatatc gtcggtaaac cgatggctca gctactcttg atggcagatg caactgttac
    16681 tgttgctcat tctaaaaccg aaaatctggc tgaactggca caagaagcag atattttagt
    16741 cgtagcaata ggacgtggac attttgtcac aaaagaattc gtaaaaccag gtgctgtagt
    16801 gatagatgta gggatgaatc gtgatgctaa cggtaagctg atcggtgatg tgaaatttga
    16861 tgaagtggag cctattgcag gctggatcac tcctgtgcca aagggtgtag ggccaatgac
    16921 tatcacgatg ctgatgtatc aaaccgtaaa atctgccgaa gcttttggag caggtgaata
    16981 gatggcacaa gaatatttaa ctgtcactac attaacgaag tatttgaaaa gaaaatttga
    17041 tgccgatcct tatttagaac gcgtatattt aacaggcgaa atatcgaatt tccgtttacg
    17101 tgccaatgcc catcaatatt tcagcttaaa agatgaccat gcaaaaatat ctgctattat
    17161 gttcaaagga gcattccaaa aattacgatt ccagccaaaa gaaggaatga aagtccttgt
    17221 cgttgggcgt atttcattat atgaagcggg aggttcttat caaatctatg tagagcacat
    17281 ggagcctgat ggaataggtg ctttatatca agaattggaa gaacgaaaag aaaagctgat
    17341 gaaggaaggc ctttttcaag ggcctaaaaa aatgctgcca cgtttcccaa agcgaatcgc
    17401 ggtccttacc agtccaagcg gagcggttat ccgcgatatc atcacgacgg tgaaaagaag
    17461 atatccaatt gtccaattgg ttttgttccc aacagttgta caaggaaacc aagcagcgga
    17521 caatgttgtc aggaatatcc agagagtaga agagatgggc aatttcgata caatgatcat
    17581 cggtcgtggg ggtggttcga ttgaggattt atggccgttt aatgaagagc gggttgctcg
    17641 ggcgatttat caagctaata cgccggtgat ttcatctgta ggacatgaaa cagataccac
    17701 gatcgctgat ttagtagcag atgttcgggc tgccactcca acagcagctg cagaattagc
    17761 tgttcctgtt ttgtcagaag agttgatgcg cattcaagaa cggcaagcta gattgcagca
    17821 ggcgtttgta cgccagatcc agcgcaaaca agaacggttc gagcgtgctc gacgttccta
    17881 tgtatttcgg cagcctgaaa gattgtatga aggtcagacc atcaaattag accagttgaa
    17941 acagcgatta tatcaagcta cacagcaaat ttatcatgcg aaagaaaaac aaacgatcgc
    18001 attaagccac caattggaac aagtggctcc gctttatcga gttaaagcag ctcgccaaga
    18061 aactgcttat ctagaaaaac gcttagaaga gaaaatccaa caatatatga aacaacagca
    18121 gcagcgtttt gctcaagctg ttcaatctct tgatttgttg agtccattga aaatcatggg
    18181 aagaggctac agctatacga cgttaaatga tcaagtagta aaaagtgtca ccgagattca
    18241 tcaaggggat ttgctgacga tccattatca agatggaatc gttaaaggac aagtacaaga
    18301 gatagacaaa ggagaataaa aatatggaaa atccaacttt tgaagagtca ctgcaagaat
    18361 tagaaaaaat tgtcatgcag ttagaacaag gagacgttcc attagaatca gctctagatt
    18421 cgtttaaacg aggaatggaa ttaagcaaac attgccaaga tacattagct aaagcagaag
    18481 agaccttgac gaaaatgatg acagaatcaa atgaagaagt tgattttgac ggaaacgagg
    18541 aaagctgaga tgagattaac tgacttttca gctattcatc tacctgctgt agaaaaagaa
    18601 atcttgtctt ttttagatga gcatacaacg gatagaggac tctatgatgc gatgagttat
    18661 tcagtgaaag caggcgggaa aagaatacgt cccttattac ttttaacggc cgttgcttcc
    18721 tttgatgagc ctattgatgt tcccgtctat caagtagcag ctgctttaga aatggtgcat
    18781 acgtattcct tgatccacga tgatttgcct gcgatggaca atgatgatct tcgtagagga
    18841 aaacctacca atcataaagt attcggcgaa gcattagcta tattggccgg agatggtttg
    18901 cttacaggag cattccagct aatcagtatg gcacacttag gtaattctcc taagcttctg
    18961 ctgcttcagc aattagctgt ttgtgcggga tcacaaggta tggttgctgg gcaagctgca
    19021 gatatcgagg gcgaatcgaa aaagctttct ttagaagaat tagcatttat tcatgaaaga
    19081 aagacagggc atttgattcg ttatgccttg ctggctggtg gcatattagc gaagcaacct
    19141 gaagaaatct tattgctact tcaacgatta gccgaacatt taggtttagc ttttcagata
    19201 agagatgatc tactcgatgt gattggtaca acgaaaacat tagggaaaac agctggtaaa
    19261 gatgaacgta tggaaaaaaa tacttacccg cgtttattag gcctagaaaa gacacgtgag
    19321 gcgttggaga ttgagctgtt atccgccaac aagatcatag acaaattaga agaggacgtt
    19381 ttttcttttg atggcgggct gatgcgccag atgatcaagc aatttgatgt ggagaaatga
    19441 gggaaagaat ggaaaaagaa cgcgtagatg tattagcggt caaacaagga ttatttgaaa
    19501 caagagaaca agccaaacgt tcagtgatgg ctggtttgat ttacaacgaa aaaaacgagc
    19561 ggtttgataa accgggagaa aaaattccag tgagtagtga attaagagtc aaaggtaaaa
    19621 aacttcctta tgtttctcga gggggattaa aattagaaaa agcactcaaa gcatttgatc
    19681 tatctgttga aggaaaaaca ttgttagata ttggtgcatc cactggcgga tttactgatg
    19741 cagctttgca aaatggcgca aaaatgagtt atgctttaga cgttggctac aatcagctag
    19801 cttggaaaat aagacaagat cctagagtcg tcgtaatgga aagagtgaat tttcgttatg
    19861 caaaacccga agactttacc ttaggaattc cagaagttac tgttatcgat gtttctttta
    19921 tttcactaaa actgatgctg cctccattac atgctatttt aaaagaagag ggagaagtga
    19981 ttgctttaat caaaccccaa ttcgaagcag gcagagaagc tgtagggaaa aacggaattg
    20041 ttcgtgaccc tcagacccat caaaaagttt tagaagacat tttgtcattt gcggcacaag
    20101 gtggatatga tgtgctggaa ttaagttatt ctccgatcac ggggggagaa ggaaatatcg
    20161 agttcttggc tcacttgagg aaagtacccg aaagcggaac aatcaattca gctattaata
    20221 tggcagaagt ggtttcaaat gcacacgaac agtttgacca taaataaatt gtaactgtga
    20281 aaatcaagtg agaagtatgc ggattcttct ttattatacc aaggaaataa gctatcattg
    20341 attaagaaga atatgctaag gagcgaagac gtaatgagaa aaaaagatcg gcatcgtttg
    20401 attactcgat tgttgagtga gcaagatatc cgaaagcagg aagaatttgt tgaaatcctg
    20461 aaaagcaaag gaatatctgt tactcaagct acgatttcca gagatataaa ggaactgaaa
    20521 ctgatcaagg taccggcttc agatggcggc taccgttata gcataccagc tgaaacaaac
    20581 gaagatgtaa atactaaatt ggaaaaacta ttaaaagacg ctttcgtggc agttgaccaa
    20641 atggaaaaat ttgttatttt gaaaacattg ccgggaaatg cttcggcagc agcaaatttg
    20701 attgataaac gttacaagaa agaattattt tcgattatca atgatgacga taatgttttg
    20761 atgattacac gaactgaaga ccaggcagtt ttattgaaga aagacttcct gcattacctt
    20821 taagttgagg agcgaatgtg atgctacaag aaatcagtat tactaacttt gcgattattc
    20881 cggaattgcg gctttctttt cacgaaggaa tgaccgcgct gaccggagag actggtgcgg
    20941 gtaaatccat tattatcgat gctttaggtc tgttagcagg aggaagaggt tcaagcgatt
    21001 atatacgtca aggagcagaa aaatgtgtgc ttgaagggtt gtttgaacta ccaaaacaag
    21061 aaggattctc tgaactgatg gttgaattag ggatcgaaac agatgaggac aatctgattg
    21121 ttcgacggga tatgtcctta actggaaaaa atgtttgtcg agtgaatggt catattatca
    21181 cattagctaa tctgagaaga atcggcagtt atttagtaga tatccaagga caaaacgaac
    21241 atcaggaact gctccagcct gaatcacatc ttgctttatt ggatcgtttt ggagatgtag
    21301 ctttccaaca gaagaaaaag agttatcagc aagaatatat ctcttatcgt gagctggaaa
    21361 aaagggtacg aaaagtgcag caaaatgaaa aatcctatgt tcagagaata gatatgctcc
    21421 atttccagca agaagaaata gctgctgctg atttgcaagt cggagaagaa gagaaattaa
    21481 aagaagaaag agaaaaactt agcaattatc aaaaaattgc tgatggatta gctgcaggtt
    21541 acggagcact gacgaataat gaacaaaaca gtgtagatgg tgttggcttg gccgtttcag
    21601 aactgcaagg gatcgcccat ctagatgtgg agtatgaagc aatttatgaa aatatccaaa
    21661 gtgcttacta tttgctgcaa gatgcaatcg gcgatatgag tcgtcagatt gatttattgg
    21721 agttagatga gagtcgttta gaagaagtta cgcaacgttt agaattaatc cgacagttga
    21781 aacgtaaata cggcgaatcc attgagtcaa tattggctta ctatgacgaa atcaccgaag
    21841 agctagcttc ttctgatttt tcagaaggtc aattggacaa aatgaaagag gaactagagc
    21901 aaaaagagct tctacttcag caacaagccg cagatcttca tgaagcgcgt aaaaaaatcg
    21961 caaaagaatt ggaaaaatcc attctgcatg aattgaaaag tctgtatatg gaaaacactg
    22021 agtttgaggt acgtttctta aaagaagaaa atagacaatt gaatcatgat ggatttgacc
    22081 aaatcgaatt ttacattacg accaatccag gagagccact gaagcctttg gtgaaagtcg
    22141 cttctggtgg cgaactgtct cggatgttgc ttgctttgaa aactattttt tcttctgagc
    22201 aaggtgtgac aagtattatt tttgatgaag tggatacagg tgtgagcgga agagttgcac
    22261 aggccatcgc agataaaatt tctcaaatat cgaaatactc tcaagttttg tgcatcactc
    22321 atctgcctca agttgctgca gtcgccgact atcaatatta tattgtgaaa gcagtgattg
    22381 atggacgtac gcaaacttct gtttcagagt tgaaaacaaa agaaagagaa gaagaaattg
    22441 cacgtatgct ggctggaagt gagattacaa aactcacact cgaacatgca aaagaactat
    22501 tgaaactcgc aaaaaggacc tgagccacct cgcagtggtt caggtccttt tcagcagctg
    22561 atagctatat tttattttta catgacactc attacagcag tcaatacaac agatccaatc
    22621 gttaaaatca gcattgtcca aatgacaaat tttgttactt tagcaaaagt acttgtttgt
    22681 tttttttcac gcattgtttt caacctcgtc attaattagt tgattcaagt gtacaatctt
    22741 ttttccattt ccacaagagg gcttttttat aaaaacttcc ctttttttaa ataataggta
    22801 gttacgatac aaataaataa tgttaataga actagccata taaaggcatc atccctttca
    22861 gcaataggta acttaatgtt cattccatag atactgccga cgattgtcgg tatagttaaa
    22921 ataatcgtta aagaagttaa aattttcata atattattca gattattcga tacgattgct
    22981 gaaaaagtct gattcatttg ttctactagt tttaattgaa tgcgagaagt agtcattgcc
    23041 tgctctgttt ccaccaatac atcacgtaaa tgatttttca aagcatgatt ttcttggaaa
    23101 agtttatttt gcgctagttc tttcaatgca tctaaattag cagaagtcgc ttctctgaaa
    23161 taaacgaggc ttttttggat atccatgatt tgataaagtt gtttgttttc agtggatact
    23221 tgaagtttgg cttccaaagt atcgcattga gattgaagcg tagctaaata actgttgtaa
    23281 gagagtgtga cctgccaaat gaattgaaag aagatattga gattaggcga aatatcactt
    23341 tttggaaagg tctggctaaa gactttcttt aaaaacagtg gttcatgatt cgtaattgtg
    23401 ataagcttct ttttgggcgt caaaataata gagagcgggt atgtatccac ttgaaaataa
    23461 ccgctaggac ttgttttagc aaaaggatat tgtaacaata ataacgctgg ctttgtcaac
    23521 tttgattgat tgaattcttc tgtacgggaa ttttctgcat cgtccaatat ggaagtgatg
    23581 taatctgacg gaatttcaaa ttgatgtgtc agctgatgaa tctcttcttg attaggacgt
    23641 tctacacaat accagatcgt ttggtcagtt tcctttccgg tattacgcag tttctcatta
    23701 tctaatgtaa aatatttgat catgattttc ctcctgttgc ctgtttcttt tattataacg
    23761 gatagggaat tggaatacat ggaatgtgtt tgtaagatat agaatataac tgcataaatt
    23821 taaataaaat gaaacagttg tgtaaagtat atacagtata cttgaagcaa cgataaaaaa
    23881 ggagtttacg ttcatgggca cattcacacc acttatcttg ttttggtata tttacccggt
    23941 aatcgttttg tttggttgcc aatttcttgt aaaattattt tcgttaaatc gtcgttttaa
    24001 aataaaagcc cctgatttgg cgattccttt tttgtggggc ggtatgcatg cattgtctag
    24061 aaatacaggg acaatttcta tcttaccgtt tttctttatt tctgttttgc taatgggaat
    24121 ttgtattgct gttttccaag catattatta tgaagaaatt atttatccgc gttatttcaa
    24181 gatgacttgg cgtttggttt ttctgttgac aatcgtcttg tacgctgtct tgatcattgt
    24241 gaacatactt tcttacctat gaaaaaaata gaaaagctgt aaaaagtctt ttaaaaggct
    24301 ttttgcagct tgatttttaa aaaaatgttt atgaataaaa aaagttgttc ccggatttcc
    24361 cagaaaaggt ggtagaaagt gggggattgt ggtagactaa ttttagttag tggaggaatg
    24421 gggggctttc aatgttgatg ggtgaattcc aacataatat tgatgcaaaa ggacgtttaa
    24481 tcgtgccctc aaaacttcgt gaagaacttg gcgaaaagtt tgttctgaca cgcggattgg
    24541 atggctgtct tttcggctat ccgatgagcg aatgggaaaa tctggaagct aaactgaacg
    24601 aaatgccgtt ggctaaaaaa gacgcacgta cttttgtgcg attcttctat tcggctgcca
    24661 ctgaatgcga acttgataaa caaggacgaa tcaatatacc cagcacgtta agaaattatg
    24721 cagctttgac aaaaggttgc gtagtcatcg gtgtatctaa ccgaattgaa atttgggatg
    24781 agacacgatg gcaagatttt tctgcagcag cagaagagaa ctttgacgaa attgctgaaa
    24841 gtatgattga tttcggacta taagaatagg aagaggctga ctaatgactg aaacatttca
    24901 acactataca gtcatgttga aagaaacggt agatggattg aacatcaaac cggatggcgt
    24961 ttatgtagac tgtacactcg gcggtgccgg acatagtgaa tatttattaa gccaactaag
    25021 ttctaaaggg catctgtatg cgtttgacca agatcaaaaa gcaatcgatc acgccaagct
    25081 gcgtttagct tcttatgtcg aacaaggtat ggtcacattt atcaaagcga acttcagaga
    25141 attagaagaa cgcttgagtg agcatgtaga taaggtagac ggcattttgt atgatctagg
    25201 ggtttcctct cctcagctag atgaagcaga acgtggattt agttatcatc aagatgcacc
    25261 gttggatatg cgcatggatc agtcagctcc tttatccgct tatcacgtaa ttaatgaata
    25321 ttcctaccat gaattagtaa agattttctt ccgctatggc gaggagaaat tttccaaaca
    25381 aattgctcgt gaaatcgaac gagtacgaaa aacaaaacca atccaaacaa ctggtgagct
    25441 tgtcgaaatc attaaacaag tcatcccagc tcccgcaaga agaaaaggcg ggcatcctgc
    25501 aaaaagaatt tttcaagctg tgcggattgc agtaaatgac gaactcggtg ccgaagaggc
    25561 ctctttagaa caggcaatcc ggttattgaa agtcaatgga agaatcagcg taatcacatt
    25621 ccattcattg gaagacagaa ttgtcaaaag tatgtttaaa gaatatagta cggtacaaga
    25681 tctaccaccg ggacttcctg tcatacctga cgaattccaa ccagaactga aagtcattac
    25741 tcgtaaacca atccttcctt cagaggaaga gctaacagaa aacaatcgat cacgcagtgc
    25801 aaagttacgt attgcagaaa aaataagaat gaaagaggag tagaatgatg gcagaattaa
    25861 agaaaatgca agattacgaa tatgatttac ctgaattggt ggatcagccg gaacaacaaa
    25921 tgcctgattc ttcttcgaat caagaaatca ttcttccaca atcaccggca aaacgattaa
    25981 agcagatttc tgctttggaa aaaattgctg tggcaagcgt ggcgattgct attgttgctt
    26041 tatgtgtttt aacagttatg ctgcgcacaa atatcagcgg agctgaaaaa gaaatcacgt
    26101 caatacaaac agaaatcaat gataaaaagc aagaaaaaac gagtttagaa caagaaaaaa
    26161 acgaactttc tcgtactgaa cggattaaac aaatcgcaga agaaaaagga ttgtctatta
    26221 atgacgacaa tttaaggaaa gtgaagtaaa tgagtcttaa aaataaaatt cggcggttta
    26281 tggaaaagaa aaatctaaat ccgatgaaca atcgcaaaaa agtaggtatc attttatttg
    26341 ctacgagtat tggattgttc tttttatttg ccgtccgttt ctcgtatatc gttattggag
    26401 gtcatgttgc tggtacctca ttagctgaaa aaacaaaaca gttgtaccaa ggaagtgaag
    26461 tagtaaaagc aaaaagagga acgatttatg atcgtaacgg tgtggcgctc gcagaagatg
    26521 cctcctctta ttcaattaaa gcgatactct caaaaacata tacctctggg gataaaaaac
    26581 tgtatgttga agaaaagaat tttgataaaa tagcagaaat cctgcataag aatctttcta
    26641 tagacaaaaa agatgcactg aatattttag aggacggcgc aaaaaaagag ctgtatcaag
    26701 ttgaatttgg tagctatggg aaaaatatct cccaagaaac caagcaaaac atcgaagcgg
    26761 acatgaaaaa agaaggtgtc gctggtcttt attttgtcga ccatcaggct cggatgtatc
    26821 caaatggcgt cttttcttct cattttattg gatacgcagt tccagacaaa gatgagaatg
    26881 gcttagttgg taaactaggt ttggagtctg cttacaatga tatcttgagc ggtaaagatg
    26941 gtaagattat ttatcaaaaa gataattttc aaaatcctct gccaggtaca gtggcagaag
    27001 aagaaaaagc tgtcgacgga caagatatct acacgacttt agacagcaga ctacaaagtt
    27061 atttagaaac actgatggat caagtaaatg aagaatatca gccagaagaa ttgacagcag
    27121 tcctgatgaa agcaaaaacc ggagaaatct tggcaatggg acaacgacct actttcaatc
    27181 ctgaaacaat ggaaggattg actggaaaag atgctatctg gcgtaatttc ttggtacaag
    27241 atagttatga accaggatca accatgaaag ttttcactac tgcagctgct atcgaagaag
    27301 gagaattcaa cgagaatgaa accttccaat ctggaaaaat ccaagtagaa gatgctacga
    27361 tcaatgacca tgactttggt gaaaaaggtg tgctgaccat gcgtcaagct ctttcatggt
    27421 caagtaacgt cgggatggtc atactggaac agcgattagg cggacgatgg tataactatt
    27481 tacaaaaact gggatttgga caaagtactc attctggatt agatgatgaa gtaaacggtg
    27541 ctttacctac attaaatatt gtcgaccgag caatgagtgc ttatggacaa gcggtaggtg
    27601 tgacgaattt ccaaatgatg aaagctttca cttctattgc gaataacggt acaatgattc
    27661 aacctcgata tatcagcaaa gtggtggatc cccaaactgg agaagagcga acaactcaaa
    27721 cagaagttct agggcaacct ttttcaaaag aaacaacaga aaaagtccgt gaatatatga
    27781 gagatgttgt cgaaagcgaa aactacggta ttgcttatgg tgtatatagt gtacctggat
    27841 acaatgtatc ggcaaaaacc ggaacagccc aaatcgcttc tgatacaggg ggatatcaaa
    27901 caggagatac agcctacctg tattcgattg tggagatggt tccttctgaa gatccagact
    27961 atgtcttgta tctaacaatg aaacacccta agacatatga tcgaatggca ttggctaaaa
    28021 tcgcaaatcc attgatgaaa cgggcaatgg attttaaaga aactgaagaa gattcagata
    28081 cagaaacaaa aacagaaaaa gtatccgtag ccgattatcg taatcttgaa gcggacgttg
    28141 cagcagctga tgctcaaaaa agtggactgc aacctgtagt gatcggtaat ggtaaaaaag
    28201 tacaaaaaca atctactgcc aacggtgatc agttgatctc tggagaaaaa ctgatcctat
    28261 atactggtgg tgataagctg atgcctgacg taacaggatg gtcaaaagca gatatcatga
    28321 agctggggaa aatcctcggt attgaagtta gttttgatgg agatggttat tgtgtcaaac
    28381 aagaacttgc tccatatgaa aaaatcactg aagacaaact tagttttact ttagaagaat
    28441 aagaagagaa ataggagaga aaagagcatg gaatggacac aagcattgat tcccattgtc
    28501 agcagttgtg caatgacaat tgccgcaatg ccgctattta ttggttattt tcaaatgaaa
    28561 aagcaaggtc aggcgattcg tgaggaggga ccaaagtggc acaatagcaa agccggaact
    28621 cctacaatgg gcggcttagt gtttctgatc ggctctattt tgacaggaat ttgggttgga
    28681 gcttggcaaa aacagctaac tcctactctt ttcatcttgc tttttgtatt agcgttatac
    28741 ggagtaatcg gctttcttga tgattttata aaaatattca agaaaagaaa catgggactg
    28801 aactcgaagc agaaattgat tggacagatt ctagggggaa tcatctttta tcttgtttac
    28861 cgttctgaag gttatccagg tgtattgaat ttcttcggac tagatctacc tttaggaatc
    28921 atttatggta ttttcgctct cttctggctt gttggatttt caaatgcagt aaatctgaca
    28981 gatggcatcg atggattagt tgctggctta ggaagtatct cttttgcagc ttacggtcta
    29041 attgcttggc atcagcatca gtatgatgta ttaatcattt gcttaagtgt tttaggaggt
    29101 ttactgggtt tcttcgtcta caacagaaaa cctgccaaga tttttatggg agatgtcggt
    29161 tcattagcgt tgggcggact tttagcggca atttctataa tgctaaacca agaatggaca
    29221 ttgcttttga ttggtttgat ctatgttatg gaaacagcaa gtgtgatgct tcaagttact
    29281 tcctttaagc ttacaggaaa acgaattttt aaaatgtctc caattcatca tcactttgaa
    29341 atgtgcggat ggtcggagtg gaagattgat acagtttttt ggttgatcag cattgtgact
    29401 tcgttgatca cattatggat cgtttggtag gagatgacgg gaaatgaaaa aaatatcaac
    29461 atatgaaaat aagaaagtgc ttgtcttagg actcgcaaaa agcggagtaa gtgcggccaa
    29521 attattacat gaattgggcg cacttgtcac cgttaatgat ggaaaacctt ttgacgaaaa
    29581 tccggaagca caagagctgc tttctttagg gataaaagta ataacaggta gtcatccaat
    29641 cgaattgttg gatgaagaat tttcattgat ggtcaaaaat ccagggattc cctacagtca
    29701 tcctttagta gcaaaagccc aagaaatggg tattccggta attacggaag ttgagctagc
    29761 ttacgaagta gcggaatgcc caattattgg gattacagga acgaacggaa aaacaacgac
    29821 aacaacgatg acaggactac tactgaatgc aggagcagat caaggaattg cacgtttagc
    29881 gggtaatatt gggtatccag caagtggtgt agcgcaagaa gcaaaatcag aagataaaat
    29941 tgtgatggaa ttgtctagct tccaactcat gggaatcaca gatttccgcc ctcatatagc
    30001 ggtgattacc aatatctatg aagcacatat tgattatcat ggtacaagaa aagaatatgt
    30061 caaagctaaa tggaaccttc aaaaaaacat gacagaaaaa gattatctga tccttaactg
    30121 gaatcagtca gaactacaag aattagcgca aagaacaaaa gcacgcgtac tgcctttctc
    30181 gacaaaagaa gtgttggaag acggtgtgta tgctgacgat tactcaatat actataaaaa
    30241 agaaaaaata atggaaatat ctgaacttgg cgtaccaggt aagcataatg tagaaaatgc
    30301 actagctgct atttctgtag caaaattgta tggtatatca aatgaagcta tacgagaaac
    30361 gttgcatttt ttccatggcg taccacatcg tacgcaatat gtaggagaaa tccaaggcag
    30421 aaaattttat aatgattcaa aagcaaccaa tattttagcg actaaaatgg ctctaagtgg
    30481 atttgaaacg tctaaggtcg tgttattggc tggcggatta gacagaggaa atacatttga
    30541 tgaattaatt ccttcattaa aaggaatcaa agcaatggtc gtatttggcc aaacaaaaga
    30601 aaagttgatg gatgctggaa aaaaagcagg catcgagaca atagtaacag ccgattctgt
    30661 agaacaagca gttcctttag cattagaaaa cagtacagat ggtgatgtag ttttattatc
    30721 accagcgaat gccagctggg atcaataccc aaattttgaa actagaggaa acagattcat
    30781 ggaagctgtg aaccgattaa aatagaaaaa gtagaagcga gcgataaaaa atgaaaattt
    30841 tggttacagg cggaggaaca gggggacata tttatccagc tcttgccttt gtcaattatg
    30901 taaagactca agaaccgaat gctgaattca tgtatgtggg agcaaaacga ggtctagaaa
    30961 acaaaatcgt ccctgataca ggaatgcctt tccatacctt ggagattcaa ggatttaaac
    31021 gaaaaatttc catgcataac atcaagacgg tccgattgtt tcttaagagt atccgtcaag
    31081 caaaaaaaat cctcagtgat tttcaaccag atatcgttat cggtactgga ggatatgttt
    31141 ccggagcggt agtgtacgct gcagccaaaa tgggtattcc aacagttatc catgaacaaa
    31201 acagtgtacc aggtgttacc aataaatttt taagccgata tgtggatcgg atcgctcttt
    31261 catttaaaga tgcggcttcc ttttttcctg aaaacaaagc agttcttgta ggtaatcctc
    31321 gagcacaaga agtagcagat actaaaaaat cagatatttt gaaaacattt gatttggatc
    31381 cagaaaagaa aacagtcttg atttttggcg gtagtcaagg agcacttaaa atcaatcaag
    31441 cagtatcagt ttttttaagt gaatatattc cttcttctta ccaagttttg tatgcttcag
    31501 gagatagata ttatgaagag atcctaaata aaataaatcc tgaaatacaa aatattagtg
    31561 tccagcctta tatcaaaaat atggcagagg tcatggcttc cagtgatctg ctggtggggc
    31621 gtgctggtgc aacttcgatc gcagaattca cagctctggg gttaccggca gtgttggttc
    31681 ccagcccata tgttacgaat gatcatcaga ctaaaaatgc aatgagtctt gttcacgcag
    31741 gagcagcaaa aatgattgca gataatgaac taacaggtga atcactaagt cagacagtca
    31801 acgaaatcat gggtgatgaa gaattgcaaa agcaaatgtg ccgagcttct aaagaacaag
    31861 gaatccctga tgcttcaaaa cgtctttatg acttagtaaa acaaataatc aaaaaataaa
    31921 ggcggtggtc ttagtgagta agaaaaaaga accaaaaaaa ttgtctcatc cgtcttctga
    31981 tgaaaacaat ttgactcctt ggcaaaaggc taaccgaaaa tatctggcag aacaagagat
    32041 gaaaaaccaa gagccaaaaa aagaagacat aacattagat acaccccttt cagattctga
    32101 agaagaaaaa acggttcaag aggaacagca agaagaaagc cagtccgaga aaaaaatcga
    32161 attttttgaa gagatcaagc aaaagaaaaa cggtggacca tataacggtt cttttttgaa
    32221 ccggctgccc aatttaaaaa gtcaacggca caaagtacta tttcgtcggt tagctttgat
    32281 catcactgta ttgggtatac cgctgatttt tttgatctat tatgtttctc cttatagcaa
    32341 attacaagca gttgcagtat caggcaataa gacagtcaac agccaagaaa tcatctctga
    32401 tacaaaattg tcattaggag aaaatgtttg gggacagtat tttcatcgat ctacttatat
    32461 cgatcgcctt aaaaaagcac agccaagaat cgaaacagca aatatacatt tcaaagggat
    32521 gaatgaattc gatttggatg taacagaata taaagagatt gctttgatcg caaaaaacaa
    32581 tcaatactac ccagtgattg aaaatggaac agtattagat gaaaaagtag caaatcctac
    32641 aaaaaatctc cctatcttgg aagagttcaa agactctgca aaaatcaaag aattaacaaa
    32701 gcaatacaat cagttatcat cagaattaca aaaagcaatt tctgaaatca agtacacgcc
    32761 aagagcaagc aataaaaatc tgatccaatt gaatatgaat gacggcaatc aagttattgt
    32821 aaatatcaat aatcttgcga accaaatgaa atattattcg caagtagcca aagatatgga
    32881 tgaaaaaggt gtgatcgaca tggaagttgg tatcttctcg catccttacg gtagcactca
    32941 agaaacggaa gaatcgggcc aatcggaaga aacaactgaa agtgaagaaa atgcggatca
    33001 aacaaacgaa tcaagtgaag aggcagaaac gcaaaaagca caaacacctg gatcgtctag
    33061 cacaaacgga tcatctgatt caaatgattc aagtgaaaca agtcaaatag aagataatcc
    33121 aagtacaact ccgtcaagtt taaatgaaaa ttgataaaac aactttaaaa agtaagaatg
    33181 tactttctaa aaaccagtaa tttatggtag aattggaagc agtgaatata tctattaata
    33241 agtatatttt aaaacggacg ctagttgttc gcttgtatat ggaatagtaa gtaggaggga
    33301 atcccattca tggcaaaaac aggaatgtat gtaggccttg atattggaac gacatctgtt
    33361 aaagttgtcg tggctgaata tatcgacagc caaatgaata ttattggagt aggaaacgca
    33421 aaatcagaag ggattaaccg aggcattatc gttgatatcg ataaaacggt ccaagcgata
    33481 caacgagcag tacgacaagc agaagaaaaa gcaggtatcc agatcaaagg cgtaagtgtc
    33541 ggtttgccag caaacatgct tgaagtagaa aattgccagg gaatgattgc agttaacgga
    33601 gattcaaagg aaatcaccga tgaagatgtc agaaatgtgg cttcagctgc ccttgttcgt
    33661 tcaatacctc ctgaacgtca aatcgtgtca atattgccac aagattttac tgtcgatggg
    33721 ttcgagggaa tcaaagatcc tcgtggaatg atcggcgtaa gattagaaat gtacggtctg
    33781 ttgtttacag gacctaaaac gatcatccat aacatacgta aatgcgtgga aaatgccgga
    33841 ttaatcgtca acgaaatggt gattactcct ttagcgctga ctgaatcaat tctttctgac
    33901 ggagaaaaag attttggtac gatcgtcatt gatatgggtg gcggccaaac aacaacggct
    33961 gttatgcatg ataagcaatt gaagtttacc aatcttgacc aagaaggtgg cgaatttgtc
    34021 actaaagata tctctattgt attaaatacg tcatttaaca atgcagaagc gttgaaaata
    34081 aactacgggg atgcataccc agaacggaca tcaccagatg aagaatttcc agtagatgtg
    34141 attggtcagt cagaaccagt gaaagtcgat gaacgctact tgtcagaaat tatttcagct
    34201 cgaatggaac agattttcaa caaagcaaaa gatgcattgg accaaatcga agcattagag
    34261 ttgccaggtg gcgtcgtatt gacaggcgga gctgctagtc ttcctggtgt tgtggacttg
    34321 gcacaagaaa tcttcggcgt aaatgtaaaa ttgtatgttc caaatcacat ggggctgaga
    34381 aacccggtat ttacaaatgt aataagtatc gtggattatt cagcaaactt gagtgaagtg
    34441 tatcaattgg caaaaattgc tgttacgggt gaaacctcag cagctcgtca aatggtagtt
    34501 gaacaagaaa caacaaacac atatgagagc tatgaagcac ctgaagaaac aatctacgat
    34561 gagccggaac caaaagagtc cggagaaaat gtaaaaaata aaatcaaggg tttctttaca
    34621 aatatttttg attaattcat cctgggagga ataagatatg gaattctcaa ttgataataa
    34681 tatcaatgac ggcgcagtaa tcaaagtcat cggagtcggt ggtggcggtg gaaatgctgt
    34741 aaaccgaatg attgaagaaa acgttaaagg tgttgaattc attacagcca acacagacgt
    34801 gcaagcatta aaaaattcaa aagctgaaac agttatccaa ttaggcccca aatatactcg
    34861 tggtttaggt gctggttctc agccagaagt tggacaaaaa gcggcagaag aaagtgaaca
    34921 atccttacgc gaagctttag acggtgcaga tatgattttc atcactgcag gaatgggtgg
    34981 aggaaccggt acaggtgctg caccaatcgt tgcaggtatc gcgaaagaat tgggcgcatt
    35041 gactgttggt gtcgtgacac gtccattcac ttttgaagga ccgaaacgtg gccgttttgc
    35101 tgcagaaggt atcgctcgtt tgaaagaaaa tgtggataca ttattaatta tctcaaataa
    35161 ccgtttatta gaagttgtag ataaaaagac accgatgctt gaagctttcc gtgaagcaga
    35221 taatgtttta cgacaaggtg tacaaggtat ctctgatttg atcacagcgc caggttacgt
    35281 taaccttgac tttgctgacg tgaaaacagt gatggaaaac caaggtacag cattgatggg
    35341 gatcggtgtg gctagtggag aagatcgcgt agtagaagca acgaaaaaag caatctcctc
    35401 tccattgctt gaaacatcta ttgatggagc tgaacaagta cttcttaaca tcacaggcgg
    35461 tttggatatg acattgttcg aagcacaaga tgcttcagat atcgtagcaa atgcagcaac
    35521 tggcgatgta aatatcattc taggtacatc tatcaatgaa gaaatgggcg atgaaatccg
    35581 tgtgacggtc atcgcaacag gtatcgatga atcaaaaaag gaacgcaagt ctagccgacc
    35641 agctagacaa gcacaaatgc aatcacctgc tcaaaagact gtattagata tggatcaagc
    35701 taaaccaact tcttcagaag aagaaaacag ttttggcgat tgggatatca gacgtgaaca
    35761 aaatgttcgt cctagagttg atgattccaa ttttgacaat atcgaaaaaa aagaatttga
    35821 tacattcaac cgcgaagaaa caaaatctca tggcgatgat gaattaaata cgccaccgtt
    35881 tttccgtcgt aaaaaataaa ggagaggaag agcacatgat tgctgacaac ttgcagaaaa
    35941 tcaagcaaga aattcaggat tcgtgtgctc ttgttcatcg tgatccgaaa gaagttacat
    36001 tagtagctgt aacaaaatct gttgaatccg ctcaagctga agaattggtt agagctggcg
    36061 ttatgaattg tgcagaaaac cgagtagata aattattaga aaagaaacaa gatttatttg
    36121 attttcctga aataaagtgg catttaattg gtaatttaca gcgcagaaag gtaaaattga
    36181 ttgtaaatga aattgattac tttcatgcgt tggacagttt aagattagca gaagaaatcc
    36241 agaagcggtt agagaaagaa ttatcctgtt ttattgaagt aaatgtttct ggtgaggaat
    36301 caaaacatgg aatttcacca gatgagcttt taccgtttgt ggaatcttta gctgcctgca
    36361 caaaaatcaa ggttgttggg ttgatgacta tggcgcctaa agaagcttct gatgagcaaa
    36421 tccataaagt gtttggtacg ctgaaagaat tgcgtgatct tgttcaagca aaaggttatg
    36481 cccatgcacc atgtagtgaa ttaagtatgg ggatgagtca agactttcaa attgcgattg
    36541 aagaaggtgc aacatttatc cgtgtaggaa cagcgctatt caaagacgaa taaaggagga
    36601 acaaaaatgc cgcttttaaa cagaggagca attgctaatt ttttcggatt agctgatgag
    36661 gaagagtacg aataccaaga ttatcctgaa acaacaaaaa aggctgtaca gccaactaaa
    36721 aaaaatacaa cacagaatca atcaactcat tctgtatctg ctgcgaatac tcatgaaaaa
    36781 caaaaaacgg cgacttcacg tcctgtaacg catgaaagta ttcagccggc tgaaaagaaa
    36841 aaagtaattg aactacatca atcacctaca aaaactgtag cgaaagaaag aacagcttca
    36901 agaacctcta cacaacctaa agcaaatctt gctggaaaaa tcactgtaat ggaaccaaga
    36961 gcttattctg aagctatggc gattgctaaa cgaatcattg ctggagaagc aaccttagtg
    37021 aattttcatt tagtagaaga aaaacaagcg agaagaatcg ttgattttct aacaggaaca
    37081 gtttatgcac tagatggaga tatcaaacgt gttggagatg agatttttct ttgtacaccg
    37141 actgggatgg agattgacag ttcaaccgct caatcttttg cagatgcgaa tttgtttgat
    37201 ctgtaagagg aggaactacg atttatacta ttgcactatt acttcattta cttcaacggg
    37261 cagcctattt ctatagcatt atcttgatgg tatatgcatt gctctcttgg tttccaggcg
    37321 ggtatcaatc agggctagga cgattattag ctaagatctg cgaaccgtat atcagtttgt
    37381 tcgatcgtct gcctttgagg attggaccct tggatttcac aattttaggg gcaatcctga
    37441 tcttgaactt agccgtacaa ggtttagcac agatcgttat atggataact gtccatttag
    37501 tttattgatt gaagcaacaa aatctttatt ctcagaatag ataggagggg aaaattttgg
    37561 atgcaaatgt ataccagcac tttcgggcag atgaacgtac atttatcgat tcggtaggcg
    37621 attggattga acaggttcaa ggacaatatg caccctatct gaccgaattt cttgacccaa
    37681 gacaatccta tattttagaa acactgattc gacaaagcag tgatttgcgt ttcatgtttt
    37741 atggcggata tgaacaggca gaaagaaaaa gatgtttgat tttccccgat tattacgaac
    37801 ctgtagagga agattttgaa acagcattgt atgaaatcca ttatcctagc aaatttgcca
    37861 gcctaagtca tgggaaaatc cttggaactt tagtgggaac ggggatcaaa cgctcttact
    37921 ttggcgatat catctcggac ggtgatcgct ggcaagtatt tattgcaaat gaggtggatc
    37981 attttgttgc tgcacaagta acaaagattg gaaaggttgc tgtacgcttg gaaccaatca
    38041 aatacacaga aatgattatg ccgaaagata gctggacaca agaaagagga acagttagtt
    38101 ccatgcgact agacagtgtg atctctgaga tttataatat ttccagacag cggtccaagc
    38161 agctgatcga agctggtaaa gtaaaagtga actggacaga aaatacaaga cctgattttg
    38221 tacttgaact attagatatt atttcagtca gaggttatgg cagagtccag atccaagaac
    38281 ttgaggggaa gacgaaaaaa gaaaagtaca gggtactgtt cggtgtatta cgtaaataaa
    38341 ataaaaaggt ggtttactca tggctttaac tccattagat atccaaaata agacattccc
    38401 gacaaaaatg cggggatata atcaagacga agtagatgat ttcttagatt tagttgttcg
    38461 tgactatgag gaattgactc aaagaaatcg agaattagaa aaagcagtca aacattctga
    38521 agaaaaactt gagtacttca atgaattaaa agatgctttg aaccaatcaa tcatcgtagc
    38581 tcaagatacg gctgataaag taaaaacaag tgcaagcaag gaatccgaag tgatcgttac
    38641 ttctgcacaa aacaaagcag atgagttagt tgcgaacgct gaaaaacgtg cacatcaatt
    38701 aacaactgat gcagaagaaa aagcaagaaa aatcttgaca gatgcaacag aaaaagcaag
    38761 acagcttgcg acagaaactg aagatcttaa gaaaaaaaca cgagtattcc atcaacgtat
    38821 cagcttgatg cttgagtctc aattagaaca agtgaaaagt ccggaatggg atgaaatttt
    38881 acaaccattc tccagctacg tgactgacag ccatgaagtg atcaaagaag ttttagcaaa
    38941 acagcttgac aatgaaaatg atactgatgt aaactcagac acaggagtca tagaagcacc
    39001 tatgacggca tttgatacac aggctattga tatctcgatc gtgcctggtg aaaatgaaaa
    39061 cgagtagaac agaaaagcac tttgttattc ttaaagcgag ccgatgagag tggaagttcg
    39121 gtaagacact gcatggtgaa agatcctcta cttgagacct gcttttccga aattagagta
    39181 agaagcagcg gctgacctcg ttattggtca cagagagttt gcactagata gatgcaacta
    39241 aatttgggtg gtaccacggc atgttcgtcc cttgcggctg aacatgcttt tttgtgtccg
    39301 gaaaacaaat aaaggagtgt atggttgaat gaaaatgaaa gaaaccttgc aattaggaaa
    39361 aacaaaattc cctatgcgtg gtaatttgcc aaaccgagaa ggcgagtggc aaaaagaatg
    39421 ggaagaaaat cgaatctacc aaaaaagaca agagttgaac gaaggaaaac ctagctttgt
    39481 tcttcatgat ggacctccat atgccaatgg taatatccat ttaggacatt cattgaataa
    39541 aatcagtaaa gacattatca ttcgttcaaa atcaatgtct ggctatcgtg caccatatgt
    39601 tccaggatgg gatacacatg gattgccgat tgaacaagta ttggctaata aaggcgtgaa
    39661 acgtaaagaa atgtccatgg cagaatactt ggaaaaatgt cgtgaatatg cactttccca
    39721 agtagataag caacgagcag atttcaaacg cctaggagtt gcaggagatt gggaacatcc
    39781 ttatgttaca ttagatcctt cttatgaagc tgcacaagta cgcgtatttg gtaaaatggc
    39841 tgaaaaaggc tatatttaca aaggattgaa accaatttac tggtctccgt caagtgagtc
    39901 ttctttagcg gaagctgaaa ttgaatataa agatgtaaaa tctccatcta tttttgtagc
    39961 tttcaatgtc aaagacggca aagatattct tgatgaagat acagcttttg tcatttggac
    40021 gacaacacca tggacattgc cagcaaacca aggtattgct gtaaatccaa aatttacgta
    40081 tgtattggtg gaagccgatg gccgtaagtt tgtcgtagcg aaagatttgc tagaaacagt
    40141 ccaatcagaa atcggttggg aaaatgtaac agttctaaaa gaatttgctg gacaagaaat
    40201 ggaatatatg actgcaagtc atccattcta tgaacgtgaa tcacttgtga ttttaggcga
    40261 tcatgttact ttagacgctg gtactggatt agtccatact gctccaggac atggggaaga
    40321 tgactatatc gctggtagca aatataaact atctgtagtg tcacctgtag actcaaaagg
    40381 attgtttaca gaagaagcac ctggatttga aggtatcttt tatgacaaag caaatcctat
    40441 gatcactgat ctattaaaag aaaaaggagc tttgctgaag ctagatttct ttactcatag
    40501 ttatcctcac gattggcgga cgaaaaagcc tgtgatctat cgggcaactc cacaatggtt
    40561 tgcatctatc gataaattcc gtcagaatat tttggatgaa gtagaaaaag tagagtgggt
    40621 tatcccatgg ggtaaaacac gtttgtataa tatgatccgt gaccgcggcg attgggtaat
    40681 ttcccgtcag cgtgcatggg gagtaccact tccgattttc tatgctgaaa atggagaagc
    40741 aatcatcaca ccagaaacaa tcgaacatgt ggcaaaatta tttgctgaac atggatcaat
    40801 tatctggttt gaaaaagaag cgaaagaact tcttcctgaa ggatttaccc acccaggttc
    40861 tcctaatggc gaatttacaa aagaaaaaga tatcatggat gtctggtttg attctggttc
    40921 ttctcatgaa gctgttttac gtcagcgacc agaattatca ttcccagcag atatgtattt
    40981 agaaggatca gaccaatatc gtggctggtt caactcaagt atcacgacta gtgtggctat
    41041 caatggtgta gcaccataca aatcagttat ttctcaagga tttgctttag atggtgaagg
    41101 ccgtaagatg agtaaatctt taggaaacat cattgcacca gaaaaagtga tcaaacaatt
    41161 tggtgcagat atccttcgct tatgggtatc tagtgtagat tatgaagcag atgttcgtgt
    41221 ttctatggat atcttaagtc aagtggcaga agtatatcgt aaaatcagaa atacgatgcg
    41281 tttcttatta gcgaatacag aagatttcga tcctaaaaaa gatactgttt cgtacaatga
    41341 tttacgttct gtagacaaat atatgaccgt tcgattgaac caagtaatca aagaaatccg
    41401 agaagaaggg tacgacaaat ataacttcat gcatatttac cgtacagtta tgaacttctt
    41461 gacggttgat ctatcgtcat tctacctgga ttttgctaaa gatgtagttt atattgaagc
    41521 agaagatgat tatcaacgtc gttgcatgca aactgttttc tatcaaacag ctgtagcttt
    41581 gacaaaatta ttgactccta tcattccgca tacagcagaa gaaatctggt cattcctgaa
    41641 agaagaagag gagtacgttc agttaagcga gtttcctggt tatgaagagt ttgcaaacca
    41701 agaagaattg atggatacct ggactgcttt catggacttc cgtgataatg tcttaaaagc
    41761 attggaagaa gcaagaaaca gcaaattgat tggtaaatct ttggaagcaa aactaactgt
    41821 ttatccaaaa caacaagttc gtgaaatgtt aaaagctttg gatgcagata ttgcacaatt
    41881 attgatcgtt tcaccagact actttgaagt tatggcagca gatgaacaag tgccagataa
    41941 cgctatggta tttgatgatg ttgctattac agtggaaaaa gcagacgggg aaacttgcga
    42001 tcgctgtcgc caagttcgta aagatgtagg agtagatgaa aaacttcctc atctatgcgg
    42061 tcgttgtgca aaaatcgttg aagacttcta tcctgaagct gtagctgaag gattcgaaga
    42121 aaagtaaaag ggaaaagggg gtgtgacatg ttctttgtca cacccccttt tgttatcaat
    42181 cgtttaattt tccacgttca cgataccagt tatctggttg ccagatccat tcgaatccgt
    42241 ctttttcaag tagttcgaaa gctgctttag gtcccattga tccagctttg tagttgggaa
    42301 aatccggttg tgtttggtcc caagcttttc gaatgacatc cacgatatgc caagattgag
    42361 cgacttcttc ccaatgagag aagttcgttc catcaccatt caacgcatct aatagtaatt
    42421 tttcgtaagc ttctgggcta ttttcaacca tttctgcact atttctaaat tccaatttga
    42481 ttggttccgt ttcaaatcct tgccctactt ctttcccatt caaggataaa gaaaatcctt
    42541 cagttggctg aatatagatc gttagaacat taggtggaag tgtcgtatcg tcacatggtt
    42601 catcgacaga tgttttgaat acattaacag gaacttgttt gaatacgatg ttgatccgag
    42661 tccctttttc agtcaaacgt ttgcctgtac gtacatagaa aggaacacct gaccaacgga
    42721 agttatcgat agtgaatttg cctgcgacga atgtttcagt ctctgattga gcatccactt
    42781 tgtcttcttc gcgatagccc ttgaattgta caccatccaa ttcaccttga gcatattgcc
    42841 cgcgaacgaa gttttctaac acttcttctt cgttataaat gcggatagct ttcaatgctt
    42901 tgatcttttc tgtacggatt tctttttcgg aaaatgctac tggcggttcc attgcaagta
    42961 atgctacaac ctgtaaaata tgattttgca ccatgtcttt aagtgcgcca ctatgatcgt
    43021 agtagccccc gcgatcttct acaccgaggt tttcgccaaa agtaatttgg atattgtcga
    43081 tatagcgatt gttccattga gcctcaaaaa tattattggc aaaacggata gctgagatgt
    43141 tttggatcat ttcttttcct aaataatgat caatcctgaa aatatcttgt tctgggaata
    43201 cttctctgat ttgctggttc aattcaaaag cagactggta atcagaaccg aacggttttt
    43261 ctatgatcaa acgattgaag ccattttttg tcataatatt ttgtgatttc aaatgagaaa
    43321 cgatcgttcc aaaaaattga ggtgccatag ccaaataata gacacggtta ccgtttaatt
    43381 gatagtgtcc atctaatcgg tcagacaatt cttttaatgt ctgataatgc gttgaatcat
    43441 ttacatcatg ggattgatag taaaaatggc ttgcaaaggt agttgcttct tcatctgaag
    43501 gattcaatgc acggattgtt tctttgacaa cttcacggta gtgctcatcg ctccagggac
    43561 ggcgagcggt tccgattaca gcaaaatgct cgcctaaatt tccttttctg taaaggcgga
    43621 acaaagacgg gtacaattta cgctgggcta ggtcacctgt accgccgaat atcgtaaaca
    43681 atacattttt ttcattagac atgtggatac actcctttat attttatcga caaaaatcgt
    43741 gctggccgcc ttaaagctga cggggatttt ctttctatca ttttggatag tgatcggtcc
    43801 ttcataagct gcgatgtcaa cgatctcata ttcttcgttg atattcaggt caatagtgac
    43861 taagtaatcc aacaattctt tttcatcaag cactcgtgcg atacgcactt ttgtaccgac
    43921 aggataggac tccaatgttt gtcggcgttc ttcatggaca acttcctctt ttttaggaat
    43981 cgatcctcca tgaggacaat gttcaggatg attcaaatag ttttctaaat gatctgcaag
    44041 atgttccgaa gtcacatgtt ccaatacttc agcatcatca tggacttcat tccagctata
    44101 gtctaaatgt tcaactaaaa aaacttccca taagcgatgt ttgcgaatca gactgctagc
    44161 tttttgcagt ccgcttgcag tcaattgtac accttgataa ggggaatgtt ctacaagctc
    44221 ttctttcaca agtttagaaa tcatttcact gacagatgca gctgagacat ctagactaga
    44281 tacgatttgt ttattgttga ctttcgttgt atctccacct agttctaaaa tgattttcaa
    44341 ataatcttct cgatttggtg tcatattcga tcatcctttc atggtaaaaa accatcatta
    44401 gtaagtgtaa caaaaaaaac gttaattgac tatttttcta aataaaaaac aaaggatttt
    44461 tagacgtttt tacaacaaaa aacgaaagat gatagagaag actcattctt tcgtttataa
    44521 aggatatata tatacattgg gagggatcta tttttcagat aacaacttat atgaagtgtc
    44581 tgcagattcg tcataaagag tttgttcggg ataagaaaag ataagataaa aaccatactg
    44641 atcacgtacg actaaacgat attcatctat ttctaccaca gatgtgccaa gagactgacc
    44701 gttgatcaaa aacgtgtaat cagatgtaat ctgtaattgt tgtttttgct ggctatcact
    44761 aaagaaccat gtaccttgat actttgagag tccttctgac ttttccgctt gttttttctt
    44821 tttcaagtaa ataaaacttg agagaacggt aatgagtgaa ccaagaaaat agatcatttt
    44881 ttttatcacc aaatcactcc tttatgagaa aataatcgca tagacatatt ctttcttctt
    44941 tatttcattg taccgaataa aagctaaaat ttctctaaga ctttcgactg gtttttttac
    45001 tgtttttcta caaattatga taggatacat agtaggaaga aaggtgacat aatttgaagt
    45061 atcagcaagt ggaaatagct ttttttattg accgcccgaa tcggtttata gcacattgta
    45121 tgaaaaaaga cggagaaata attattgcgc atgtcaaaaa tacaggtaga ggaaaagagg
    45181 tcctgatacc aggcgctgaa gtggctattg tatttgctcc tggacctaaa cggaaaaccg
    45241 cctatgatct gattgctgta aaaaagaagg gtgactggtt taatatcgat agtcaattgc
    45301 ctaatcggct ggcaattgat ggtattttag acggcacgat ccttttacca ggattaactg
    45361 gtccatttac ggtatacaag cgtgaagtaa cttatcttca ctccaaattt gatatttatt
    45421 tagagacggt ggtcggacaa aaagcatttg ttgaagtcaa aggtatgaca cttgaaaata
    45481 aagcgattgg tgcttttcct gatgcgccca cactcagagg attgaaacat ataggagaat
    45541 taacgtatgc cgcacaagat ggttatgccg cttatgtctt gtttattgct cagttcgaac
    45601 atcttcatct ggcaacgatc catgaagaaa tgcaaccagc actagctgat atggttcgac
    45661 atgcgcagca aagcggagtt caaatcctcg cctataattg tcaagtatcg gcagatgagg
    45721 taactgtcaa gcaggccatt ccatttgatg tagatatccc ttttgaagat cctatacaat
    45781 agaaagaagg taaaataatg atcaacttag gtattatcgg aacaaattgg attactcatc
    45841 aatttgtcca agcagcttta agcacaaaaa aatatgaatt gacagcggta tattctagac
    45901 atttggaaaa agcacaggaa tttggttctc attatgaagg ggatatcgaa ttcgcaacag
    45961 atttgaagac ttttttcaat attactcata tggacaccat ttatattgct tctccgaata
    46021 gtcttcactt tagtcaagct aagcaagcaa ttttggcagg aaaaaatgtg atagttgaaa
    46081 agccagcttt ttcgacgcca aaagaaatgg atgaaatcat ccatttggca aatgaacaca
    46141 atgtgtattt ttttgaagca gcaagaaata tccatgaatc aggttttaaa aagattgccg
    46201 attacttacc attaaaagac gagataatcg gtgcaaattt cagctatatg aaatattctt
    46261 cgcgctatga ccaagtatta gatggagaag aaccgaatat cttctcgact catttctcag
    46321 gtggtgcatt gatggattta ggtgtttacc ttgtatatgc agctgttgct tggtttggaa
    46381 tgccaaaaga agtccattat ttcccaagaa agatttctac tggtgtagat ggtcttggat
    46441 gggggatctt acgttatgag aattttgatg tatcgatcca gccaggtaaa atcggtgatt
    46501 cttatttacc gtcagagatt tattttgact caggaacgct agtgatgaat ggagtcaatg
    46561 caattgaaca agcacaattt catgatcgcg cgcataaaga aatcattgat ttggcggtaa
    46621 cagctgcaga aaatccaatg gcagatgaag cagaggattt tgccaatgtc atggctcatc
    46681 cgaaagatcc agcttgggga ttgttgtatg aagagtggat cgagctagct agaaatgtga
    46741 accaagtgat ttatgattta agaaaaaatg gcggcatcaa attcgatgca gataatgagg
    46801 aagattttta atgaacgaat ttgtacaagt atttcccgaa aattggcaga aaaaatatga
    46861 ggataaaggg tttatctcac cttctcttat tcaacgagca gtttttcagc cactaagtaa
    46921 taaacaaagt atagtagcgg tttctcctac aggttcaggt aaaacactgg cttatctttg
    46981 gcctctacta ctaaacgtgg aaccaggtga agcaagtgcg ttggtcattt ttgcttcttc
    47041 tcaagaacta gctattcaag tagcagatgt tgcacgtgaa tggggaaaag acaaagagtt
    47101 gaaagtccaa tctttggtgg gcggagccaa cgtcaaacgt cagattgagg gtttgaagga
    47161 aaaaccagaa atcttgattg gtacaccagg aagaatattg gaattgatga aagcaaaaaa
    47221 aataaaagca catcaagtga aaacaatggt atttgatgaa gcagaccagc tatttgacgc
    47281 tgggaacagc caaatcattg atcaaattct tcatcaagct ccaacagagt atcagctagc
    47341 ttttttttca gcgacagcag atcgttccct tgaaagcatt gaaaaaatca ctgggaaaac
    47401 gtttgagaca attgacgtga cagcagagga cgattctcga aaaggactga gacattactt
    47461 tttacgtgta ccgatacgaa agaaagatga ctacttgaga cgtctcacgc atatagaaga
    47521 ttttcatggt ctgattttct ttaatcaact gactgaatta ggcgtaatgg aagaaaaatt
    47581 gctgtataga ggtgtaccgg taggaagtct ggcctctgat cagaacaagc tactccgaaa
    47641 agcagcgcta gaacaattca aaaagaaaat ggtcagagca cttttgacca cagatgtggc
    47701 ggctagaggt ttagatatta caggtcttcc ttatgtagtg aatgcagaag ttccgttaag
    47761 tgaagaagct tatttgcatc gttcgggaag aactggtcga atgggtaatg aaggaatagt
    47821 aattacactc gtacaagata ataatctaag agatttaaaa cggcttttac gtccatcaaa
    47881 tataacactt gaagagattt ttttatacgg aggtaagctg caaactgagc agccaaccaa
    47941 agaagatgca gctcctgcag taaataaaaa gtatgcgaaa actttttctg gaaaggagca
    48001 gaacccagaa tataacaaag aaaaaataag aaaaaaagtt aaaaataaat caaaaaaaga
    48061 gagaaataaa ggagcaaggc gcaaataagc gcctttttat gctatgatta tgaaaacggg
    48121 aacaaaattg gttgccagag gaggggttat gtgaaagaac gtcaagaaga gatcttgcag
    48181 ctattgacag aaaaccaaca aggattgaca gcaagtgatg tagctgagcg cttaactatc
    48241 gatcgaagca atgcaagccg atatttaagt gaactataca aggcccatca tattgtaaaa
    48301 accgctggcc gaccagtcgt ttactctttg ccaacggaaa agtcaaaatc tgatgaagtg
    48361 catgtcgact cttctacgca agtgactttt gaaacactcg ttggagaaaa tgattcttta
    48421 aaagtcagca tacagcaggc aaaagctgcg attctttatc caccgcgggg gttgcatacg
    48481 attatttttg gagaaactgg tacagggaag tcgatgtttg ctgaatgtat gtatcatttt
    48541 gcaatcgatt cagagatgct ttctgcagat gcgccatttg tttctttcaa ttgtgcggat
    48601 tatgctcaaa atccgcaact gctctttgga cacatctttg ggatcaaaaa aggggcttac
    48661 acaggagcag ctcaagatag tcccggtcta atagccaaag cagacggcgg tatattgttt
    48721 ttagatgaga tccaccgttt accgccggaa gggcaggaaa tgctgtttac tttcattgat
    48781 aaaggtattt accgtccgct tggagaaagt gcacaagtac atgaagcatc tgttcagatc
    48841 attggggcga cgactgaatc ttcagaaagt ttcttatcta cgttcaatcg acggattcct
    48901 atggcaatca ccttgccgaa tcttgcttca cgttcactgg atgagcgtta tgaaatcatc
    48961 tctcttttta tcaaacaaga agcgaatcgt ttgaatcaac gtatcgatat cgaaaaagaa
    49021 gcgattcttg ccttcatgct ttatgatgcg gaaggaaata tcggtcaagt gaaacgagac
    49081 ttgaaactag tctgtgcaaa atctttttta cattaccgta ctcatcatga gaaaaagcta
    49141 atcattcgaa aagaagaact ttcccttcaa gtacaaaaag gattactgaa aatcaaggaa
    49201 ataccggaac gtctcgaccg attcatggac agcaaaagtc agtatttgac atttgaacca
    49261 ggatttgctg atgttgtctg gtcacaagat ccagaacgaa acatgcaggt ctataacgat
    49321 attgaggaaa aagtcacttc tctttccgaa accggtgtgg agaacattga tctagagacc
    49381 ctcatttcaa aagatgtgga tgcttatttc cagacatatg tcaaagaatt gactaaaagt
    49441 tcgattccca aagatctttt gccagatgaa atctggcggt taaccaatca attgtatgat
    49501 gtggctgaaa aacggttaga ccgtatttat aatgaaaaag ctcgttttgc ttttgctttg
    49561 catctgcaaa gtacattgga tcgtgtgaga gaaggtcata tgatcgtcca cccagatttg
    49621 aataacgtac ggaaaaattt taagagggaa ttccaggtag caatcgatct ttcaacgatc
    49681 attgaagaag aagaacaagt tgagattcct tttgatgaaa tcggctttat tagtatgttt
    49741 ctttctatca atctaggaga aagtgagcct gttaaagaaa acaaagtaga tgttctcata
    49801 ttgatgcacg gcagacagac tgcttcaagc atgttggaga tggcacaaga actattagga
    49861 acaaaagtag ggaaagcttt taatatgcca ctggttatgg aagttcaaac aatgtatgaa
    49921 gaagtgttac aatatgtcaa aaactatcaa gagcatttga cgaatggcct actcttgtta
    49981 acagatatgg gatcattaaa caccttcagt gatttgattt atgaagagac tggcattcgg
    50041 acgaaagcta tcacgatgac aagtaccatg attgtgatag aagcgatacg gatggcaagt
    50101 gttggaagaa gcttagaaga tatttatcaa aatatccagc tttcctttga atcgatcgta
    50161 cgtgatcagt tcaaagcgga aaagtctgaa actttacagc gtaaaaaagc cgtaatcgtg
    50221 acatgcttta ctggtgaagg agtagctgcc aaattatatc agcgtattat gccagtgatt
    50281 aatcaaaata aggtagaact gatccagatg cagtttttag aacgtgaatc attcaaaaaa
    50341 cacatcgatg ccttattgga agaatatgag atcaaagcaa ttgcgggaac agttgatgtt
    50401 gattatcaaa atatcccatt tttttcagcc tatgacgttt ttgatgatga aaaactaaat
    50461 attttaaagc gtatagctga tgatgagatc ccgacagcta aaattgtcga ttcacttgct
    50521 ggatcattaa gcgatgtctt ttctattgat gaactgatcc gttcattgca aaagacagtt
    50581 cagcagatcc agaccgattt gtcgattatc gtggaacctg gagtagatac tggaatcgtt
    50641 atccatttag ccttcatgtt agacggattg atcaaacaag aaagccatcg gcaatttgag
    50701 aaactgtcta ttttctcaaa aatttatcgt ttggaaatgg atatcgttcg ggcaaacttg
    50761 atggcactag aacgaaaata tcaggtaaaa attccagaag atgatatcgc atttcttaca
    50821 caaatgtttc ttgaaaataa aataaaaaaa tgaacacact aatcatactg tttacacact
    50881 aaacatctgt gtgcgcacta taaaaaagag ctaaaaagca tgaaaacgct atttcagctc
    50941 ttttttttat tggcatgctt cttgcgttat ataaaagtgt aaaaaaataa aaggagtgtt
    51001 aaaaatggca aaaaaaacaa tcatgttagt ttgttcagca gggatgagta cgagtttatt
    51061 ggtcacaaaa atgcaaaaag cagcagaaga aaaagggatg gaagccgata tttttgcggt
    51121 ctctgcctca gatgcagata ataatttaga atctaagaat gtcgatgtat tattattagg
    51181 tcctcaagta cgtttcatga aagctcaatt tgaacaaaaa cttgcgccta aaggtattcc
    51241 attagatgtc atcaatatgc aagactatgg catgatgaac ggagaaaaag ttcttgcaca
    51301 agcagaaaat ctaatgaaat aaatcaagta tgcagttggg ggtataacaa cgtggaagat
    51361 caacaaaatc tagaagccat catggggtta atcatgtttg gcggtaatgc aaagagcgat
    51421 gcaatggaag cgattgcggc tgctaaaatc ggtgattttg agttagcgga taggaaaatc
    51481 gctgatgcag aagaatcact tatacaagcg catcatgcac aaacagacat gttgacacaa
    51541 gaagcacaag gaaatcatat gcaagtgaca ttattgactg ttcacagtca agatcactta
    51601 atgacatcta ttgcgtttac tgatttagca aaagaaatca tcgaacttta tcgtcgcgta
    51661 tacagcgaat aaatacaact tcttttttga acggaagaag aaaaattttt gaacggattt
    51721 tttattttgt tataaggaga actctcttta tataaaaaac ttataggagg aagtaaaaaa
    51781 tgaacggact atcaagttgg atggagaaat acatcctgcc ggttgccgca aaaatcggag
    51841 cgcaaaaaca tttagttgct ttgcgtgatg cttttatcgg cacactgccc gcaacaatgg
    51901 cgggatcagt cgctgtaatg atcaatgcaa ttattcgtga tttaccgcaa cagtttaaca
    51961 gtacctatgc tgacagttta gcagcagaca aaggaatctt tgccgtattg aatgtcatca
    52021 tcggaatcaa tggttttgtc tggaacggta cactagcaat cgccggattg atctttgcct
    52081 tttcttgggg gtataatctt gcccgagctt atggagtaaa tgatctagct ggggggatcg
    52141 ttggtttagc taccttgatt caaggtattt cctttggtcc agcattatca gcagcattag
    52201 atgtgaatgt tccttcaaat gtcgcagatg caatcaatag ttctgagatt ggtgcaacga
    52261 ttgcagatgg cacactgtca gttggattat ggggttggct aaaactagat catttgaatg
    52321 gaaacgctta ttttacagtt atgatcatgg gagctatttc agtcattatt ttttgtaaat
    52381 tgatgcttgc caacattacg atcaaaatgc ctgattcagt accaccagca gtatctaaag
    52441 catttgcagc cattttacca gcgacgatcg ctttatacgt cattgctatt atcaattata
    52501 tcgtaggtcg tgtagctgat gggcaactga tcattgattt ggtgcaaaaa tatattgcag
    52561 aaccattcct aggattatct caagggttgg gagcagtatt gatcgtcaca gtatttgttc
    52621 aagtattctg gttctttggt attcatggac caaatgtatt ggcaccagtg ctagagggaa
    52681 tctggggaca agcacaacta atcaatattg atattttcca aaaaggttat aacggaaaaa
    52741 ctggtacacc agccgtgtta gatgcaatcg aagatggaaa agcttatatg tgggtccgcg
    52801 gatcgttcga tgcttttgca tggtttggcg gatcaggcgg aacgatcgtc ttactgatag
    52861 ctatcttgat tttctctaaa cgtgcagatt atctaacagt agctaaatta tccattgggc
    52921 ctggtatctt caatatcaac gaaccagtga tgtttggtct gccaatcgta ttgaatgcaa
    52981 tcatgtttat cccattcttg attgctccag tagtagcaac agcaattgga tggacagcta
    53041 cttatcttgg cctagtcgct ccggtatcgc agcaagtcac atgggtagta ccgccgttct
    53101 tattgtcatt cttagcaaca ggagcggatt ggcgggcacc gatcgtaaca ttagtatgta
    53161 tggtcgtgac tttcttgatt tgggcaccat ttgtcatctc tgcaaacaaa atggaccctg
    53221 ccgcaggcga acaacaataa gatgaacgtg aggagcggga cgctttaagt ttcgttcctc
    53281 ataatgaatt ttcgaggagg aactgaaatg attacaattg ccagtgcaat gcaacaagat
    53341 gaaatcaaag aattgttaga aggatacaat gaagaaggaa tgacttttac atttaaagaa
    53401 aaacaaggaa tcaagctgtt ctttgaaaca agtgcagaag atccggaagt tgcggctaaa
    53461 aaagcaaagg aactaatcaa agcacagcct tggggaacag tcctttattt tcaatcaaca
    53521 gctgtttaga aaatggttta aaaagatagg atggttgaga tgataaaaaa cggtttattt
    53581 ttatgtagta ttggttcttt gatcgtgttg tatagtttga atccacattc gcaaaggtat
    53641 gatttgtata gtatggtcac aggtcttttt ctaacaggat taggaatcta tttcttcatg
    53701 aaggggaaaa aaagagaaga agcaaaggag aaaaataact aatggaaatc acgaaaaaat
    53761 taaatattcc agcatcgttt ttttacgata aagttatgga ctctgtcctt ttcgatgtac
    53821 gtaaagcgac cggcaaatca gtaactagaa aacagctgaa aaatttggag tacgtcaaac
    53881 aattctcgca aaataaccgg gctcgcataa aaatcgaaga agtcattgaa aaccagtctt
    53941 ataagtttcg tacatcgaca acgaagaatg aattcgtcgt tcattatcaa atcaaaccat
    54001 tggacgattc gacctgtgag gttcattaca cagaaaaaat ggagtcttat ggcatgcttc
    54061 aaaagttgaa tgatatgctt ttaggaacaa tcttgatgta ttttaaacgg agacgtttca
    54121 aaaaaatgct agatatgatc gaagcaacgt attaaatcaa tgaaacatgg tactatttag
    54181 ttattgaaaa atgaagtaag ctagaaggaa tttttcatag gaagatagat ctttcctgcg
    54241 aatcctcact agcttttttg taggaagggg cagcaaaatg acaaacaaag taagagagct
    54301 aggtgtatct tcgattgagg aaatgtttga tttagccact tatgcattta atggggcaga
    54361 tacacctgaa aggcgagaac gttttcgtac acttgcggag aattcttgga attacggatt
    54421 ttttgatgag gaggatcggc taacaagtca agtcatggcg accccttttc cagtgaattt
    54481 ttacggacaa gagtacctaa tggccggcat tggctatgtt gcttcttatc cagaagcaag
    54541 gggacaaggc gggatcaatc agatcatgga aaagatcctt gaagattgcc gtgatcgtaa
    54601 agtaagctta tcttatctgg cgccattctc ctatcccttc tatcggcgct atggctatga
    54661 acaatcattt gataaaatca gttatcaact aaacagtcgt gatgtgccgt ttatcaaaaa
    54721 aaaatctgga aaaataaagc gtatggattt tgaagatgca aaagctgcaa tcagaagaat
    54781 ttatgaacag atgccggaaa accaacgagc tggtctgaag cgcgaagact ggtggtatac
    54841 gtataaattc aagcaaaaag gcaattacca gtttgctttg cattttgatg ataatgagga
    54901 agcaacggga tatatcgttt atcagcttgc aacgtcttcc tttattattg cggagtgggg
    54961 atttttggat catgatgctt tttgcagcct tgttcgcttc gtaagttctc acaatggtgc
    55021 ttttgaaaca tttgaatatt catgcggcta cggcggtaat gatcaaaatt atctattaga
    55081 aaatccattt gcttctgtaa tgatcacacc ttatatgatg gcgaggatcg tagatatttc
    55141 tttgtttttg gaaaattatc catttaaaaa gagacaagct gcatttgccc tacaaataga
    55201 agaagatcat tatgcgaaat ggaatgaagg aatcgtggaa gtaacaatcg aaaatggaaa
    55261 aaatcatctc tcaaaagtag aacaaacaaa actcccaatc gttcgaggaa gtatccaaca
    55321 tatcacgcag ctattattag ggtatcgtaa agtggaagag ttggtattcc aagaaagaat
    55381 acaggtgaca aaagaatatg aagaaacgtt aagctcaatc ttgccacagc aacagccaat
    55441 tcttaatgac tatttttgat aaaaaacggg tgatgacaat atttttgtca ccaccctttt
    55501 gtttttcatt tggcatttga aggaaaatgt taaagtaaat cctctttttt cgtaaatttg
    55561 aattttttgt tttcttttgt tttagggttt tcttttttgt ggtcttggat tgcttctttc
    55621 gtaatctttt cccgattttt tttagatgaa tctaagcgtt ctgcgtatac tttttctttt
    55681 ggcttatcat tcattggaaa ggacctccct acattatttc attctacctc tagtttatca
    55741 tctgttaagg actagtggaa acgttttgcc taacttataa gctgattttt ttagcagata
    55801 agcttgcaag taaaaaacaa acaagctaca attgatttat tgaaattgtt cctgtagctc
    55861 agtaggatag agcaatcgcc tcctaagcga taggtcgctg gttcaattcc agtcaggaac
    55921 gtacaaataa cccctgtatc ctttgtgata caggggtttg ttttgtgttt gtgccaaaaa
    55981 tgtgccaaac tagttatcat ttttatataa actatcgaac acagcattga ttttttcttt
    56041 atcctgatct tcaagctctc gaacaatatg aagataagta gacattgtag tttctaaact
    56101 gctatgtcct aaacgtttcg atacgctaag tatatttact ccttgataaa gtaaaataga
    56161 tgcatgtgta tgccttagtc catgcaaagt aaattgcttt tcaatcccta attcttttaa
    56221 ttttttgcgc aaatatttgc tgacggcgtt tgatgaaact aatccatttt ttaagttgaa
    56281 aaaaacaaaa ttatgagggt ttttaacttc aaaattctcg aataattctt tttgattgat
    56341 tttaaacttt tttaagagat caatcgtatg tttatcaatg gaaattttcc tatttgaagt
    56401 ttcgtttttt gtttttcccc attcatttaa tttataattc catgttttat taatagtgat
    56461 gatttgatct tcgaaatcga tatcttccca tgttaatcct agaagttcag caaatcgcat
    56521 tccagtagca ccagcaacta acacgagcat aggagaagag tactgcgcag aaaggttttc
    56581 ttctacgagt ttcattaaag atttaaattg atcataatct aaatatttat cttcttttgg
    56641 cttcaatgaa tcttttcctt tgattactgc ttttctagtt ggatcaaacg gaattaatcc
    56701 ttcttctacg gcatctttca acgatgctct aatatg
//
LOCUS       DAIGQM010000013        56349 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.013, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000013 DAIGQM010000000
VERSION     DAIGQM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.013"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            290..1135
                     /locus_tag="NOA48_000720"
     CDS             290..1135
                     /locus_tag="NOA48_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0789006.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="NOA48_000721"
     CDS             1416..2636
                     /locus_tag="NOA48_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCI0789007.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="NOA48_000722"
     CDS             2633..5353
                     /locus_tag="NOA48_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0789008.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="NOA48_000723"
     CDS             5337..6281
                     /locus_tag="NOA48_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0789009.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="NOA48_000724"
     CDS             complement(6350..7360)
                     /locus_tag="NOA48_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0789010.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="NOA48_000725"
     CDS             complement(7540..7884)
                     /locus_tag="NOA48_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0789011.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="NOA48_000726"
     CDS             complement(7877..8311)
                     /locus_tag="NOA48_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCI0789012.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="NOA48_000727"
     CDS             8449..9186
                     /locus_tag="NOA48_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789013.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="NOA48_000728"
     CDS             9179..10390
                     /locus_tag="NOA48_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789014.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="NOA48_000729"
     CDS             10594..11376
                     /locus_tag="NOA48_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCI0789015.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="NOA48_000730"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="NOA48_000730"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCI0789016.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="NOA48_000731"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="NOA48_000731"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCI0789017.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="tadA"
                     /locus_tag="NOA48_000732"
     CDS             14092..15021
                     /gene="tadA"
                     /locus_tag="NOA48_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI0789018.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /locus_tag="NOA48_000733"
     CDS             14978..16027
                     /locus_tag="NOA48_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCI0789019.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /locus_tag="NOA48_000734"
     CDS             16024..16302
                     /locus_tag="NOA48_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCI0789020.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /locus_tag="NOA48_000735"
     CDS             16277..16747
                     /locus_tag="NOA48_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCI0789021.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16764..17066
                     /locus_tag="NOA48_000736"
     CDS             16764..17066
                     /locus_tag="NOA48_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789022.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17083..17454
                     /locus_tag="NOA48_000737"
     CDS             17083..17454
                     /locus_tag="NOA48_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCI0789023.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /locus_tag="NOA48_000738"
     CDS             17426..17785
                     /locus_tag="NOA48_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789024.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="NOA48_000739"
     CDS             17957..18964
                     /locus_tag="NOA48_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0789025.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="NOA48_000740"
     CDS             18989..20173
                     /locus_tag="NOA48_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCI0789026.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /locus_tag="NOA48_000741"
     CDS             complement(20610..22193)
                     /locus_tag="NOA48_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0789027.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22771..22914)
                     /locus_tag="NOA48_000742"
     CDS             complement(22771..22914)
                     /locus_tag="NOA48_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCI0789028.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23137..23616)
                     /locus_tag="NOA48_000743"
     CDS             complement(23137..23616)
                     /locus_tag="NOA48_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0789029.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23689..23973)
                     /locus_tag="NOA48_000744"
     CDS             complement(23689..23973)
                     /locus_tag="NOA48_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789030.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24051..24245)
                     /gene="ssrS"
                     /locus_tag="NOA48_000745"
     ncRNA           complement(24051..24245)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="NOA48_000745"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24317..25603)
                     /locus_tag="NOA48_000746"
     CDS             complement(24317..25603)
                     /locus_tag="NOA48_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCI0789031.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25741..26412
                     /locus_tag="NOA48_000747"
     CDS             25741..26412
                     /locus_tag="NOA48_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCI0789032.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26378..26866
                     /locus_tag="NOA48_000748"
     CDS             26378..26866
                     /locus_tag="NOA48_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCI0789033.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26879..27826
                     /gene="prmA"
                     /locus_tag="NOA48_000749"
     CDS             26879..27826
                     /gene="prmA"
                     /locus_tag="NOA48_000749"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCI0789034.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27827..28591
                     /locus_tag="NOA48_000750"
     CDS             27827..28591
                     /locus_tag="NOA48_000750"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCI0789035.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28824..31037
                     /locus_tag="NOA48_000751"
     CDS             28824..31037
                     /locus_tag="NOA48_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCI0789036.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31048..31494
                     /locus_tag="NOA48_000752"
     CDS             31048..31494
                     /locus_tag="NOA48_000752"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCI0789037.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31665..32924
                     /locus_tag="NOA48_000753"
     CDS             31665..32924
                     /locus_tag="NOA48_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCI0789038.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33013..33960)
                     /locus_tag="NOA48_000754"
     CDS             complement(33013..33960)
                     /locus_tag="NOA48_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0789039.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34354..35646
                     /locus_tag="NOA48_000755"
     CDS             34354..35646
                     /locus_tag="NOA48_000755"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCI0789040.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35661..37430
                     /gene="aspS"
                     /locus_tag="NOA48_000756"
     CDS             35661..37430
                     /gene="aspS"
                     /locus_tag="NOA48_000756"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCI0789041.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37539..38414
                     /locus_tag="NOA48_000757"
     CDS             37539..38414
                     /locus_tag="NOA48_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0789042.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38680..40563
                     /locus_tag="NOA48_000758"
     CDS             38680..40563
                     /locus_tag="NOA48_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI0789043.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40638..40922)
                     /locus_tag="NOA48_000759"
     CDS             complement(40638..40922)
                     /locus_tag="NOA48_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0789044.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40912..41646)
                     /locus_tag="NOA48_000760"
     CDS             complement(40912..41646)
                     /locus_tag="NOA48_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCI0789045.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41775..42398
                     /locus_tag="NOA48_000761"
     CDS             41775..42398
                     /locus_tag="NOA48_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCI0789046.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42590..43711
                     /locus_tag="NOA48_000762"
     CDS             42590..43711
                     /locus_tag="NOA48_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCI0789047.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43718..46846
                     /locus_tag="NOA48_000763"
     CDS             43718..46846
                     /locus_tag="NOA48_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCI0789048.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46865..50059
                     /locus_tag="NOA48_000764"
     CDS             46865..50059
                     /locus_tag="NOA48_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCI0789049.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50205..50912)
                     /locus_tag="NOA48_000765"
     CDS             complement(50205..50912)
                     /locus_tag="NOA48_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0789050.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51677..52075
                     /gene="spxA"
                     /locus_tag="NOA48_000766"
     CDS             51677..52075
                     /gene="spxA"
                     /locus_tag="NOA48_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0789051.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52407..53060
                     /locus_tag="NOA48_000767"
     CDS             52407..53060
                     /locus_tag="NOA48_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCI0789052.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53286..54284
                     /locus_tag="NOA48_000768"
     CDS             53286..54284
                     /locus_tag="NOA48_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCI0789053.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54460..56268
                     /gene="pepF"
                     /locus_tag="NOA48_000769"
     CDS             54460..56268
                     /gene="pepF"
                     /locus_tag="NOA48_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCI0789054.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18540 a         9724 c        11678 g        16407 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatcccaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggttt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg agactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat catgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccatggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttta ttttacttga actcattgac tgttttccct ttattttaaa
    23041 cattataaag accgatgagt gcttgccgcg tcttttgttt ttatcacggt tttttgtgca
    23101 aaaaaacctg ccgatagttg gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc
    23161 tggcaattgg ttttctaaat cagttcggac aacaagcaca tcgcaagctg cgtttctaat
    23221 aacatattca gaaacagaac caataaataa acgttctaca gcattcaatc ctgtggctcc
    23281 taacataatc aaatctactt gattatcttc tgggatttct ctggcaataa tttgttttgg
    23341 tgagccatat tctacgacag aggttacatt attcaagcca gctttcttcg cattgctttc
    23401 ataatctgcc aatgtttgct ttgccatttc agtagcttgt tctgcaagca ttccatcaaa
    23461 ggatgaaacg gtttggaaag aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt
    23521 atttcggata gctacattga ccgccttttt aaaagctaat tcagcttcat cagaaccatc
    23581 tacggcaacc atgatttttt tgtattgttg taacataagc attcactcct caagtcaatc
    23641 gtattgtact cttttattgt agaacacttt agggaaaaag agaattattt actgctttgg
    23701 ttcagcaatt ttttttgcaa atcggatact gaaggtggca gaaacaataa ttacgatcag
    23761 taaaaagacc aaggcaataa agcgttgatt gaaaaaagct gttaaaatac ccattacgcc
    23821 taaaacagca tatgcagctc cgtaaaattg taggaatcct tgatttttat catttttgtt
    23881 gatcaataca aaaaagatat cctgtttatt aaataaataa tagctaacga ataataatac
    23941 taaagtggcg ataatcatta aaatcctaat catgaacaaa tcctccaaaa taagcaacaa
    24001 atagaaaaag caatttgcca agagcaaatt gctttattct ttaaaagatg gtaatctccg
    24061 ttaatgccgt tgtttgtcct gtagtattga tcccgcgaat tcaagcaggt gggtcccatg
    24121 gtcgtagctt cgaactacca aatgataagg catgttacca gcagtgacac aagacgggtc
    24181 ccaagatatc aataaaaatg ttcggtcaac acacaaagag gacaattcga acatcacaga
    24241 tttcccacct ctatagtagc atatgaattt aaaaagagca atgagagagc tcgcagaaac
    24301 agaaccgttt tcttgtctag ttttttggag gatgcttttt ccactctttt atacggtaat
    24361 actgttgacc cagagcctgt tcatatttcc ctgtatcttt tggctgataa tactgagcat
    24421 tcttcagttt atctggtaaa tattgctgat tgacccaagc ctgatcaaaa tgatgaggat
    24481 actgataacc cacgccacgg ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat
    24541 gatcaggaac atctccagct ttgccctctc gaatatcagc aagtgctgca tctaatgcca
    24601 tgtaggcaga attggatttt ggcgacaagc aaagatcgac gacgacgtct gctagtggga
    24661 tacgtgcctc aggcaatccc aatttttcag cagctaatac agcgttcact gtacgagccg
    24721 cagcagcagg attacctaaa cctatatctt cataaccgat aaccatcaga cgccggcaaa
    24781 tacttgccag atcacctgcc tcaactaaac gggcgagata atgaagtgca gcatccacat
    24841 cacttccacg aatcgatttt tgaaaagccg aaataacgtc ataatgagca tctccatttt
    24901 tgtcatgggt aagagctttt ctttggacac attcttcaat gatcgacagt gtaagatgaa
    24961 tccttccttc tttatctgaa ggagtcgata gtgtagccag ttccagccca ttcaatgcac
    25021 tccgcaaatc gccgttcgtt gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga
    25081 ttgcttgttg tccaaggccg cgttctttat cccttaaagc atgttcgact gccaactgga
    25141 tgtcttgttc tgttaatggt ttgacttcaa agatctgtgt acggctgcgg atcgctggat
    25201 tgatggtaat ataaggattc tcagtagtcg ctccgatcaa gatgattcgg ccactttcta
    25261 aatgaggaag cagaaaatcc tgttttgttt tatctaatcg gtgtacttca tccaataaga
    25321 ggatcactgt accactcatt tttgcttctt ccgctacaac ttgtagatcc ttttttgaat
    25381 ctgtagcggc gtttagcatg cgaaatgcat aattagtaga gccggcgatc gcacttgcga
    25441 tactcgtttt tccagtacca ggaggtccat atagaatcat ggaagagagc atgcgagcat
    25501 cgaccatgcg gcgtatgatt tttccttccc cgactagatg ctgctgacca acgacttcat
    25561 cgatcgttcg aggtctcatg cgataagcca atggctgttg cataggattt tcctccttct
    25621 tgtttttacg tcccttaatt atatcatatt tagcaagatg cctagaaaga acagccttct
    25681 gttgttttgt tttcatagct tatccaacta atattgtgta tgataaagta ggtgagaaaa
    25741 atgacggata aacaaaagat agatgaattt ttttggaata aaacgacgcc agaagtggca
    25801 cgggatttat tggggatgta tttggagcat gacacaccag aaggaagatt agctggatat
    25861 attgtagacg cggaagcata cctaggtcca gaagacgagg ccgcccatag ctatggttta
    25921 agaagaacac cgcgtgtgcg ggcaatgtat gaaaaaccag gtacgatcta cctttacacg
    25981 atgcatactc atcggatttt gaacatcatt actcagccag aagggattcc tcaaggagta
    26041 atgatacgtg caatcgaacc cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga
    26101 aaaactggtc cagatatcag caacggtccg ggaaaattag tggaagcatt agcaattcct
    26161 caagaacttt atggtcagtc tatagcagat agttcgttac gcttagtttt tgagaaaaaa
    26221 aagacaccaa aaaagatcaa tgctttgcct agaatcggta tcccaaacaa aggtgtatgg
    26281 acagaaaagc cgttgcgttt tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa
    26341 aaccaaatcg agaaagattg gggttggagg aaagaaaatg aaaaagaagg atctattaac
    26401 atatttagat gaaataattg aaaaacaagt gacagactat gatgtagctt tagattggga
    26461 tacaaaaaat catacgatcg agatcgttgt tcgcttgttt gcagaaaata aagcacaatt
    26521 tgagattgat gatgcagaag ggatcgtttc gcaagaacca attatcgaat ttgaagacgg
    26581 cgtacttctt tttaatcctc agaaatctgt ttttgatgaa cgcaattatc tagcagtaat
    26641 cccttatgaa ggaaaaaaag ggttggcaaa atcagtagct gattctttag tggaatatct
    26701 aaatgaagta ttagctcaag ggcaaagcga tttgcttgat tttttggatg aagacgatga
    26761 cgaagctgta ttcgagcttc actgggataa tcagcaacta gcagaattag tagaagtaaa
    26821 acagcaaaat gaagcagata cttatttacc gtacccaagt tattaaggag tgacagatat
    26881 gaaatggaat gaagtaaaag tagaaactga aagtgaagca gtcgaagcag ttgctaatat
    26941 tttgatggag gcaggggcga gtggtgtcgc gattgaagat tctttagatg ttgaacattt
    27001 tcagtcggat caatatggtg agattttaga taaaaatgat tttacatcgc tgaaagaagg
    27061 cgcactagtc atggcttatt ttccggaaac gactttctta ccggaaatct tgccttttat
    27121 caaagatcgt atcacacaat tacctgagtt tggtctagct attggaaaaa ataaagtaac
    27181 agttagtgaa gtagaggaaa gcaactgggc aacagcctgg aagaaatact atcatccggt
    27241 gcgtattacg cgaatgctga cggttgcgcc aagctgggaa aactaccaga cagaagatcc
    27301 tctagaaaaa attatcacac tagatcctgg tatggcattt ggcacaggca ctcatcccac
    27361 gacttccttg acattgacag cactagaaac agtcttgcgt ggtggtgaaa cattgctaga
    27421 tgtgggaact gggtcgggcg tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt
    27481 ctatgccttt gatttagacg aagtagccgt tcgttcggcg aaagaaaata tggatatgaa
    27541 tgaaatagcc aaagatgtcc atgtatcagc taacgatctt ttgacaggaa tcgagattga
    27601 aagtgatgta atcgttgcga acattttagc agatatcatc ttattgatga tcccagatgc
    27661 ttggcgttta ctgaagcaaa caggcacgct gatcgtttca ggaatcattg aagagaagaa
    27721 gcaaatggtt ctggatgcca tgttagaaca agggtttatc gtggatcaaa ttttccagca
    27781 aaaagactgg tatgcaatta ttttgaaaaa accagaggtg gaatagatgc agcggtattt
    27841 tttaaaagaa tcatatgaat caaaagacta ttttgtttta gaaggggaaa actatcacca
    27901 cattgtacgg gttatgagga tggaacccga ggatgaagtt tttttggcat tcaatgatca
    27961 aatagccatt gttgcagaaa tcacggagat tactgaagag gctgtttatc tgaaagaaat
    28021 taaaaaagaa gaaaatcaaa aggaactgcc aagttcgatt accatagcga gtggctatcc
    28081 taaaggggaa aagctggatt ggatcgttca gaaatccact gaattaggag cgcaagcttt
    28141 tcttggtttc ccggcatcag cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg
    28201 acaacaacgg cttgaaaaga ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt
    28261 gccatcagta gagttattgg aaacgaaaca agatttattt gagcggctag atgattatga
    28321 cgtggtcttg gttgcttatg aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa
    28381 aattcttagt gaaacaaaac cagatagtcg aatcttagct gtctttggac cagaaggtgg
    28441 attatcccgc gatgaagtcg attattttgt agaacacaaa gggatacttt gtggattagg
    28501 accaagaatc cttcgtacag aaacagcacc tctttattta ttaagtgctg ctagctatca
    28561 atgggaatta atgaatcctt ctttcagcta acgttcttca ttaataaaag agtatcgaca
    28621 gaaagaattg aaaaaatagt caacaatttg tataatagaa acaattattt atacaatgga
    28681 tacgaaaaat cgtttgaaaa agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa
    28741 ctgcacggat tttgggacaa ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa
    28801 aaaagaaagg gggatcgatt cctgtgacaa aagaagaaat tttaacggga cccggtgtca
    28861 taaagctcgt tagtcaatac atgggtcccg aacatgtagc atttgttgag aaagcatgcg
    28921 aatacgcgac tgctgcacat gacggacagt ttagaaaatc aggcgaaccc tacattattc
    28981 atcctatcca agtcgcaggt atattagcag atttaaaaat ggatccccat acagtggcta
    29041 caggcttctt acatgatgtt gttgaagata cagaaatcac tttagaagat ctgagagaag
    29101 aatttggcga tgacgttgct atgttagtgg acggcgtaac caaattaggg aaaataaaat
    29161 ataaatccca cgaagagcag ctagcagaaa accaccgaaa gatgctgcta gcaatggctc
    29221 aagatttacg agttatcatg gtcaaattag ctgatagact acataacatg cgtacgttga
    29281 agcacctgcg agaagataag caaagaagga tcgctcagga aactttagaa atctatgcgc
    29341 ctcttgcaca tcgtctaggg atcagccgga tcaaatggga attagaagat acagcacttc
    29401 gttatctaaa tccaaaacag tattaccgta tcgtccactt gatgcagacg aagagagaag
    29461 aacgtgaaaa atacgtaagt ggtactgttg aagatattcg aatagcgaca gaagagctgg
    29521 ggatttttgc agaaatctat ggacggccaa aacacattta ttcaatctat cgtaaaatga
    29581 aagatcagaa aaagcagttc aacgaaattt atgacttgct agctattcga gtgatcgtag
    29641 attcaatcaa ggattgttat gctgtattag gagcaatcca cacaaaatgg aaaccaatgc
    29701 ccggcagatt taaggattat attgccatgc caaaagctaa tatgtaccaa tctttgcata
    29761 ctaccgtgat cggtccggca ggaaatccgg tagaaattca aatccgaaca caggaaatgc
    29821 atgaaatcgc tgaattcggg gttgctgcac actgggccta taaagaagga aaaaatgaaa
    29881 aagtagaacc agatggtatg acgaaacaat taagctggtt ccatgagata ctcgaacttc
    29941 aagacgaaag ctatgatgct tctgaattta tggaaggcgt aaaaggagat atctttagtg
    30001 ataaagtcta cgtcttcaca ccaaaaggag acgttactga gttaccaaaa ggatccggac
    30061 cattggactt tgcatacagt atccatacag atatcggtaa caaaaccact ggtgcaaaag
    30121 taaatggcaa aatggtgcag cttgattaca aattgaaaaa cggagatatc attgagatca
    30181 tgacttctcc aaattcattt ggcccaagtc gcgactggtt gaaattagtt gctactagca
    30241 aagcaagaaa taagatcaaa cgtttcttca aagcccaaga tcgagaagaa aatgtgatca
    30301 aaggccacga atccgtggtc aaatgtatta cagatctagg atttacgcct aaagatattt
    30361 tgacgaagaa caaactgcaa gaagcactcg atcgttttaa ttatcaaaca gaagatgatc
    30421 tctatgcagc tgtagggtat ggagaagtta gccccttgac gatggccaat cgtctgactg
    30481 aaaaagaacg taaagaacaa aaaatcgagc agcaaaagca agaagcagaa gaaatcatga
    30541 atcagccgaa aaaagaacct gacaaaatga aagtacgtca tgaaggtggc gttgtcattc
    30601 aaggggtaga aaacttacta attcgtatca gtcgctgctg taatccgatt cctggtgatg
    30661 atatcgttgg ttatatcact aaaggcagag ggatatccat tcatcgtcga gattgtccga
    30721 atgttcagcc tgacaaacca aatgtagcag aacgtttgat tgaagtcgaa tgggaagata
    30781 catcgaatac acgaaaagag tatgatgcag atttggaaat ttacggctat aatcgttcag
    30841 gcttattgaa tgatgtactt caaacagtca atgcgctaac gaaaaatctc aacagcgttg
    30901 aagcacggac gaataaagat aaaatggcga cgatccattt gacggttggt atccagaatt
    30961 tatcccacct aaagagtatc gtggataaaa tcaaagcagt acctgatgtc tacagtgtac
    31021 gccggacgaa tggataggag gacagatatg agagcagttg ttcaacgggt aagtaaagct
    31081 gctgtgtcag tcgatcagca agaaattgga aaaattggct acggcctact tgttttatta
    31141 ggcattcatg aaaccgatac gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa
    31201 atgcgtattt ttgaagatga acaaggaaaa atgaatatta gtgtagaaga tgtgggagga
    31261 caaattttaa gtatctctca attcacactg tttgcggata cgaaaaaagg aaatcgacca
    31321 agctttgtgg aagccgcacg accagaaaca gctattcctt tatacgaatc attcaatgaa
    31381 ggaatcagaa gtcgcggcat cacagtcgct accggacaat tcggagcaga tatgtcggtt
    31441 tctctcgtca atgatggacc tgtaacgatc attattgatt ctaaaaacaa ataaagtaat
    31501 ctggttttca ctagtaaaaa ctatgaaaca cgtcgcttaa gttagactga taaactctaa
    31561 cttaagtggc ttttttgtct gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt
    31621 aagcttaaat tatacaagtt attttttata ggaggttgct gaagatgaaa gaagtaccag
    31681 tagtagatat caaaatcaca gatttaaaaa aattgtatca aaaaggatac aacatgttgg
    31741 aggagttacg ccatgaagcg gacgctcccg tcgtcaaagc aaagattttc aataaagaag
    31801 ctatcacgat ctacggatca tcagcagcaa aagtatttta tgatccaagg aatttcaaac
    31861 gaaaaggtgc tatgccaaaa ttagtattga agacactttt tggtcaaggt ggagtacaga
    31921 ctttggatgg agctgctcat caccatcgga aaaatatttt tatggatcta atgacaccgg
    31981 aaagaatgga agattatcat cgtatcttag ataagaatct gacacaagca cttgaagcac
    32041 agcatggtca atttgaacta tttgatttaa gtaagatggt tttctttaca tctatttgcg
    32101 agtgggcagg tatcaattta tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat
    32161 atcaaatctc tatgatcagc ggaacgttta cttctccgat tgatcacata aaaggtgtcg
    32221 aaaatcgcaa aaaatcagaa aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc
    32281 ctgtggctgg aaaagaaaat gtggcattat atgcttttgc caatgccaca gatttagatg
    32341 gtcagctttt acctctggaa gtggcagctg ttgaattatt gaacatcatc cgtccaacgg
    32401 ttgctctaac tgtgtgggcg gcattgatgg gacatgcact tttcagtaga ccagatttgt
    32461 atcagcaatt aaaaaatgac ttttcgacgt tacaagatcc gtttattcaa gaaatgagac
    32521 gctattatcc tttcttccca atgctacctg cgatttcgct gaaagaagta gaagtagatg
    32581 gttatcgtat accagaaggc agttgggtta ttttagattt atatggaaca gaccatgatg
    32641 aacgaacagt tgaagcgcca gattccttta tgatcaaacg gtatgtaggg aaagcaaaag
    32701 atatttccta taaagaagaa tatgagatga ttgcacaagg cgggggaaat tttcgacaaa
    32761 tgcatcgctg tgcaggagaa tggatcactc ttcatagtct acgtgtgttt tccgatcagc
    32821 tagtaaataa gtttgagttc tctgtacctg aacaagattg gacgattcca ttcaatcagt
    32881 ttccgactta tccgaatagc cgagcgctac tttacaagaa ttagattagc ataaacttat
    32941 cgaaaaaaag gaagatcaaa cagtgctgat cttccttttt tcatattact ataaattgat
    33001 aaggtcaatt gatcaaaatc cacgaaatgc ttcatcaatg gtttgataat cttcattgga
    33061 taaatgcaaa tctaaagctt ggacattgtc agatacttgc tctggacgct tagctccagg
    33121 tataactaca gacactcgtg gattcttcat gtaccaagct aaaacaagtt gcgcaggagt
    33181 ggcttggtat cttttagcaa tggggcgaag tacatcgaca gcggttaaaa tttctctgaa
    33241 acgttctcct tggaaatctg gatttctttt tcgaggatct ccttcaccaa attgtttttc
    33301 ctcaccaagt tcatattttc ctgtcagcaa accggaagca agaggaaaat agggaacaaa
    33361 actgattttg tttttttcaa gataagggaa taattctttt tcagcctgcc gatggatcaa
    33421 actgtattta tcttctacta catcgacata tccatctgca ttcgcttctt tcaattgttc
    33481 taacgtgaag tttgacacac cgactgctcg gatttttcct gcttctttta attcgtgcaa
    33541 tgtagcaact gattcatttt ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc
    33601 gatgtaatca gtttgcagac gttttagtgc atcttccacc gattgtttga gaaactcagg
    33661 agaattatca aatgttcgcc ctttatttgg tacatgagca gcttttgtag cgatgacgac
    33721 acgtgagcga tcatattctt tttccttcag tacctcgcca atcagttctt cggaacggcc
    33781 gtttccgtaa gcataagcgg tatcgatcaa attgatcccg ctattcaaag ctgtacgaac
    33841 tacttgtttt cctgtctcat cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt
    33901 tgctcctaat ccaagctgtt ctgcgtagac ttgtgaatgt ccgattctta tttctgccat
    33961 agctgattcc tcctttttgt ctagtctaaa acaaaatacc aaaaagctga actaaaacgt
    34021 ttttgtgagg ggaaatagtc agatatctct tgactttgag actggttttt agtaggttat
    34081 aagtaatatc gaatgtcaat gaaagagcga gtaagttttt gaaactttac aagagaggat
    34141 catcgaggct gaaaatgatc taaagtttca ttagcctaaa gacactctgg agatggacga
    34201 gtgaaaagcc gtcccgcgta cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat
    34261 taggtggtac cgtgtatgaa tttcattcac ccttgttcat gatgaacaag ggtgattttt
    34321 ttatttacat agctaagaaa gggagagaaa actatgagtt tccaaagacc aaaaggaaca
    34381 aatgatattt tgccaggcga atcagaaaaa tggcagtttg tcgaagaaac agcacgttta
    34441 ttattcagag attatcagta taatgaaatg cgtacaccga tttttgaaca ctatgaagtg
    34501 atatcccgaa gtgtagggga tacaacggat atcgtttcaa aagagatgta tgatttttat
    34561 gacaaagggg aacgccatgt gacgcttcga ccagaaggta cagcaccaat cgttcgttct
    34621 tttgttgagc ataaattgtt cggcccagag tatgcgaaac cgttcaaaac tttttatatg
    34681 ggaccaatgt ttcgctacga acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc
    34741 ggagtagaag catttggatc agaaaaccct gcaactgatg tggagagcat ggtgatggca
    34801 cttgatttct tcaaacagtt ggggatcacg caaatccggc tagtcatcaa ttcattaggt
    34861 gataaagaaa cgcgtcaagc ctatcgtcaa gcattgatcg actatctttt accttttgaa
    34921 tcagagctga gtgaagactc taaacgccgc cttcatgaaa atccattacg cgtattggac
    34981 agtaaagaca aacgagatca aaaatttgtg gcagaagctc catctatctt agattatcta
    35041 agcgagcctg ctcaaaaaca ttttgatacc gttgtttcca tgctggatgc attggctgtt
    35101 ccttatgaaa tcgacagtaa tatggttcgc ggactagatt attacacaca tacgattttt
    35161 gaaatcatga gtgacgcacc aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt
    35221 tatgacaatc tagtggaaga actaggtggt ccttcaacac ctggcttcgg atttgcaatg
    35281 ggtatcgagc gattactctt gactatggag gcagaggaag tagttatccc tgcatttaat
    35341 gagttggatg cttacgtggt cgcactcgga gacgaaacaa atatcgaagc attgaaagtg
    35401 gtccaagcga ttcgaaactt tggtttttca gctgaccgcg acttcatgaa ccgtaaagca
    35461 aaagcgcaat ttaagacagc agataaagcg aatgccaaat tagtattggt gatcggtgaa
    35521 gatgagcttg ctagtcaaac gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt
    35581 tttccattag aagagatata tgaacatttt gatgaagtct atgatgaaat gactttattc
    35641 gagtaggagg aaaaaaataa atggcacaaa gaacgatcta ttgcggatta gtttccgaac
    35701 aacaattaga acaaacagtt acattaaaag gatgggtaca aaaaagacga gaccttgggg
    35761 gagtaatctt tatcgaccta cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg
    35821 aaatcaacaa agaagcatgg gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag
    35881 tgactgggga agttagaaga cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg
    35941 aattcgaagt gattgcaagt gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc
    36001 aaattgaaga tgatcaagca atcagtgacg aaatacgttt gaaatatcgt tatttggatc
    36061 tgcgtcgtcc aaaaatgact aaaaacatca aattaagaaa tgcgacaaca aaagcgattc
    36121 gtcattattt agatgataat gactttctcg atatcgaaac accttaccta gggaaatcta
    36181 caccagaagg cgcaagagac tacctagttc cttcacgtgt ccatgctgga catttctatg
    36241 cgttgccgca atctcctcaa ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt
    36301 attatcaaat cgttcgttgt ttccgcgatg aagatttacg tggagaccgt cagcctgaat
    36361 ttacgcaagt agatattgaa acaacgttct taacagcaga agaaatccaa acttacacag
    36421 agggattgat tgcgaaggta atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc
    36481 ctcgtatgac ctatgatgaa gcaatggctc gctacggcag cgacaaaccg gatacacgtt
    36541 ttgatatgga attgatcgat ctaagcgata cagtcaaaga agtagaattc aaagtcttcc
    36601 aaatggctct tgaaaacggc ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc
    36661 gctactcacg aaaagacatg gatcagttag gtcaatatgt aggacaattc ggagctaagg
    36721 ggcttgcatg gctgaaagta gaagaagacg gattgaaagg tccaattgct aaattcatgg
    36781 gagaagcaac agaagcaatc attaaagcaa cagatgcaaa accaggtgac ttgctgatgt
    36841 ttggcgcaga taaaagtgaa atcgtcgctg ctgcattagg tgctatccgg acacgtttag
    36901 gaaaagaatt aggactaatt gatgaatcga aattcaattt cttatgggta actgattggc
    36961 cacaatttga attttcagaa gaagaaggtc gatatgtctc tgctcaccat ccattcacga
    37021 tgccaaaaga agaagatatc ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag
    37081 cttatgatat cgtcttgaac ggttatgaac taggcggagg ttctatccgt attcatactc
    37141 gtgagcttca agaaaaagta ctagaaactc taggctttac aaaagaacaa atggaagaac
    37201 aatttggttt cttgttaaca gctttagatt acggattccc tccacatggc ggtattgcat
    37261 taggattgga ccgttttgca atgttattag ccggagaaga taatattcgt gaagtcattg
    37321 cctttcctaa aaacggaaaa gcagcagatg tgatgagtga tgcaccaagt atggtttcgc
    37381 ctttacaatt gttcgaattg aatattgatg taacgaatat agaagaatag ccgataaaaa
    37441 ggtaaaaagg atttgtcgaa tacgcttctt ttgacaacct tgatttaatt gaaaaacact
    37501 ttataatgaa gccataacat ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt
    37561 gggcttatca tgattacacg accaagcttt cggtatctat cgtttatgcg ttgatcgcat
    37621 cagtcgcatt gaatttcttt tatcagccag gacatattta ttcaagtggt attactggtc
    37681 tagctcagat tttgacgact ttgtcaaaat cactgatagg attcgaagta ccggtatcaa
    37741 caactttgta tttactgaat atacctttgt ttgtattggc gtggttaaaa atcgggaaga
    37801 agtttacaat tttcactttt atcacagtca ctttgacctc cctttgtatc catattttac
    37861 cggaaacagt cctatctacc gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg
    37921 gactaggtat tgggctagcg ttgagaaacg gcctatcatc gggcggtcta gatatcgtga
    37981 gtatcacgat tcgtaaaaaa acaggaaagt cgattggttc tatttcgatc tacttcaatg
    38041 cattgatcgt ttttgttgcc ggaattctat ttggctggca atatatgttt tacagtacgt
    38101 tgtctatttt cgtcagtgga aaagtaactg atgtcgttta tactaaacaa aagaagatgc
    38161 aggtaatgat cgtaacgaaa catccagaaa aagtagtaaa tgaaatccaa aactgtatgc
    38221 gtagagggat cacgatcatc aatgaagcag aaggtgctta taagcatgat aagcagacag
    38281 tattgatgac gatcgttaca cgatacgaac tgcctctact tagagaagca atgaaagctt
    38341 ctgatccaca agcttttgta agtattgcag aaaacgtcca gatacttggt cgtttctatg
    38401 aggatggcat ttagatcgag tttgacaaaa attcatgaaa tactgctgta gacagacgtt
    38461 cgtttgtctg cagttttttt ctaccatagt agaatcagca aagaaaaact gcttttttat
    38521 ttgaaatttt cttaaagttg aaaaaaagca tgtttatttt tttaaattta tgggatgata
    38581 gaaaaaaata gtagagaaag gacacgattc tacttgctat tttcacttaa tacccgtata
    38641 ttacgaatga aaaaagttta tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta
    38701 aaaaacagcc gctacatcac tgggtttgat gggctccgtt cattagctgt ggtgggtgtt
    38761 atcttctatc accttctgcc aactagtatg aaaggcggct atttgggcgt tccgattttt
    38821 ttcgtcgtat ctggttattt gatcacggat ctgctgcggc aggaatggga acaaaatgga
    38881 aaaatcaata tttggcaatt ttatgtcaga agaatgaaga gactctatcc ggcacttgtt
    38941 tttatgcttg tgacagcttc ggcttatatc actttgtttc agcgagggct gttaaacaat
    39001 cttcgaggag ttgtggtcag cagcttactg tatgtcaaca actggtggca aatcaataac
    39061 ggtttatctt atttcgatcg atttgctaat gagtcaccgt ttacgcatat ctggtcttta
    39121 gcagtagaag gtcaaaacta tttggtttgg ccgatcttgt ttgtattgtt gatggtattt
    39181 gttcgtaaaa gaaaatggat cttttatact gtgttaggta catccttcct ctccgccatc
    39241 ttgatgatga tcttgtatac accaggaggc gatccaaccc gtgtttatta cggtaccgac
    39301 actcgtctgt tttctatatg gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt
    39361 ttaaagaaaa acatcccgaa acaagcgaaa aatattctga atatcgctgg aggaatctcg
    39421 cttttggcac tgattctttg cttcttcttt ttagatgatc attacaattt catctattac
    39481 ggaggaatgc tcctagtgag tctgttatgc gtagtgctag ttgcagtgac agcacacccc
    39541 ggagcaagtt tgaatcgatg gctgacaaat ccagtattta cttggattgg caaacgaagc
    39601 tatggcattt atctgtatca gtttccagtt atgatttttt atgaagcaaa ggtgactgat
    39661 attgccgatc atgttttgtt gcatacttta gtggaaatca cattgattct aatcatcagt
    39721 gaactttctt atcgatatgt ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc
    39781 caagtgatga aaggatggtt cagcaaaccg atcatcagta agagcaaacc atgggttgtt
    39841 ccaggcacat tacttgtagc aattgcactc gttggtttcg ttacggcacc gaaaaacgct
    39901 gtaacagccg atcaaaaaca actgcaggca aaaatcgctg aaagtaaaaa attagcagaa
    39961 gaaaccagaa acaattcaga aaacaccact agttcggttg accaagcgat ccttgataag
    40021 tacgagttgt ccaaggcaca agggaataag gcacaaaaat tagaactaac ggcatttggt
    40081 gattcagtta tgttggatgc tgcaacggat ctacaagaac tttatccaaa agtagtggta
    40141 gatggagatg tcggacgaca attatatgcc agtgtaccgt acattgaaaa attaaaggaa
    40201 caagatttgt tgaaagacac tgttctgatc ggactaggaa cgaatggctc attctcggaa
    40261 gctcagtttg atagtgtgat ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc
    40321 cgagtaccga cgaagcgctg gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa
    40381 aaatacgaca atatgacgct gattgattgg tacagctaca gtaatgacca tagtgactgg
    40441 ttttatgatg atcaagtcca tccaaatcct gaagggatga cacattacat tcacttagtc
    40501 agcgaagcct tgctaggagg aagttcaagt acgaacagca gtgagacaaa cgtgacagaa
    40561 tgatagctac aaaaaacttc aggcaaaaac atttgttttt gcctgaagtt tttttatatt
    40621 taccgtgttt ttaacattca tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa
    40681 taacgttctt tttgttttcg ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg
    40741 cttcttgaag aaaatacttc tgcatggatc atcttaacag gtcttctttt ttgaagacga
    40801 gtatatttag caccagtacc attgttatgt tcctctaatc gtctagaaag atcggttgta
    40861 tatccaccat aaaatgtctg atctttacag aataatacgt aaaaataatg ttcatttgcc
    40921 atagagcatc tcacgaatct ctgcagtgta ttctccatcc atattgtaag tgatcaatgg
    40981 tggagcgact ttgaatccgt ctaatttgcc ttctttgatt ccttcaacta acaaaatatt
    41041 tgcctctttt ccaggttttg ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc
    41101 ttccatgacc tgaatgattt ctaagaaccg atcaggacga tggaccatag taaagcgtcc
    41161 atttgttttt agtagcttac ttgaaatatc gatcacttct tctaacgtcg tatgaatctc
    41221 atgacgggcg attgccaggt gtttattagg gttcgtttta tttgttggca gccctttgaa
    41281 ataaggtgga ttacagacga ctaagtcaca agaattatgt cgaacgacag ataagctgtc
    41341 tttcagatcg atggtgtgga cagtcatttg ttcatttaaa tggttaagcg cgatactacg
    41401 tcttgccatg tctgctagac gaggttgaag ttcgatagcg tcgatagccg cctgggttcg
    41461 tttacttaaa aaaagtccaa ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt
    41521 tttaggtaca cgggaaaagt gagcaagcag cacagcatct aaagaaaaag aaaacacttt
    41581 ggaactttgg ataatcttga tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg
    41641 aagcatggat tccctccaaa atgaaaaaaa tagtcgtctg tattatacta tttttattaa
    41701 aaagaaccaa ggtggcttgt caaacctcta ttttttatgc atactatgac cataagaagg
    41761 gaaaggaaga gactatgttt tatcgattta tgcgcggggt agttcgagta ctattagcct
    41821 tagttaatgg aaatgcccgc tatgagaata aagaagtttt accgcaagat gagaattaca
    41881 tactagttgc tccccatcgt acttggtggg acccattata tctggcggta gctgcagcac
    41941 ccaaggaatt cagctttatg gcaaaagaag aactgttcaa aaatccagtt ctgcgattta
    42001 tattaactcg atccaatgct tttccagtta aaagagaaaa tccaggacca agcgtcatta
    42061 aaacacctgt aaagattttg aaatcgacaa atttgagttt gatcatgttt cccagtggga
    42121 caagacatgc tacagaactt aaaggcggaa tggcattgat ttccagaatg tctaaagcga
    42181 aaatcgtgcc agctgtatat caaggtccgt tgacacttgg ggatctgttc aagcgtcaga
    42241 gagtgacagt gcgtttcggc gaaccaatcg acttatcaga tatcaagaaa acggataaag
    42301 aaggtatggc ggagatcgaa cgacgaacac aagcagcttt tgacaaattg gacaaagaag
    42361 tgaaccctga tttcaaatat gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc
    42421 ggtcttttga atctactgtc ctgttcagtt cagacttttt caatgaaaac gagggagaga
    42481 cgtcaagtct gccctctttt tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa
    42541 tggatcaaag tgttataata attagaagga cattttttga ggtgattgaa tgcgtttttt
    42601 acatacagcc gattggcata tcggaaaaaa actacaaggt tatgacttga ttgaagacca
    42661 gcgtcatgta ctatcttcta tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt
    42721 gattgccgga gacttatatg ataggagtgt cccagctgtt gatgccgtag aattatacaa
    42781 tgaattgatg gtcgattgga atttaaagga aaagatcccg atttttgcta tatcaggaaa
    42841 tcacgatagc agtacgagac tttcagcggg tacgccatgg ttcagttatt cgaactattt
    42901 tttgcgaaca cagctagcag aagcatttga accagtcgag tttaaaaacg tacaattttt
    42961 ctttcttcct tactttgaac caattgcagc gagattatat tttgaagatg acaatatccg
    43021 aacgatcaag caagcggtag ccaaggtgat agataaaatg caggagctat ttgattcaga
    43081 aaaaaaacaa gtattgatta gccatttttt tgtaatggga agtgtaaaat ctgattcgga
    43141 aacgaaaatc gaagtaggcg ggttggattc gatccctggt gaactactta caccgtttga
    43201 ttatgtagca ctaggacatt tgcataatca agctgctttg agacaggata atgctcgcta
    43261 tagcggttcc ccattgaaat tctctttatc tgagatcaac caaaaaaaag gcgtatggat
    43321 cgttgacctg acaacaggcc tggagttgaa ttttagggag atcgaacccc tgcatgatat
    43381 tgaagaaata acagcgagtt tcaaagaatt gctggatcct gccttttatc agtccgtcaa
    43441 tcgggagaat tacatctata tctatctcac tgatagaacg atcatcccga atatgatgaa
    43501 ccagcttcgg caaatatatc ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga
    43561 acaaacaaag cgcaaacgaa aagtactaga aatgaaagat cctcaaaaat tagcagaagc
    43621 attttttagt gaaatgacgg aagagcagct aactgcaaac caagaaaaat ggctcggaga
    43681 aacgttgcaa gaaatcatgg aaatggaatg atcaagaatg aaaccgaaaa aattacaact
    43741 taaaaatttt ggtcctttta tcaatgagac cgtagatttt tcacgtttga cagaagcacc
    43801 gctttttttg atcagcggga agacaggagc tggcaaaacg acgatttttg atgggatcac
    43861 cttcgcactt tttggtgaaa cttccggaag acttcgctct ggaaaagaga tgcgttcttt
    43921 gtttgctaca ccagacgaag aaacaagcgt gactttttct tttgaacatc agcagatgag
    43981 ctatgaaatc gaacgaaaac cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa
    44041 aaaacaggca gccaaagtaa cgttgaccat ttttgatggg aaaggaaaag aaataaaaca
    44101 aatcacaaaa cgtacagaag cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa
    44161 acagttttct caaatcgttt tactacccca aggagaattc cgtaattttt tggtttcatc
    44221 aagcagtgat aaagagactg ttttacgtca tttattcggt actcaatttt tccaacagtt
    44281 caatgagcga ttaaaagaaa aagcaaaaca acagcaacaa aaattggatc atttagagca
    44341 agagctgcat cttctgcaaa aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg
    44401 gtttgaagcc gttttagccc aatggacaaa ccatcaggca atactcgaaa aacaaatcac
    44461 ggaagaaaaa gaagctctaa cggaacttca ggaaaaacaa aagcaactag aaaattccta
    44521 ctatcgtttt gaaagcttga aaaaaagtta tgaagaaaaa acgatattaa taaacaagca
    44581 aaaggaatta gctgctcaaa aagacgaaat agaggaaaag aaacgatgga ttgggtatta
    44641 tgaatttacg caacgattag tcgaaccaat ccagcgccta caagaaataa aagttgaaaa
    44701 aatagaactg tcacaaaaaa gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa
    44761 ttatgaagag tggcaaaaaa atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga
    44821 agctgctcaa aaactgcaaa acaaacagat gatggtgcca attgtcgaat ccttacgtag
    44881 taaaaaacaa gacgcagaac aattaacaat ttcattggat aaagaagaat tgaatgccga
    44941 gaagctgtat caaaatctcg ctatctatca ggaaagaact cgaattcttc aagaaaattt
    45001 actggatcag gaaaaactgc aagaagatcg tcttgctttt ggacagttaa aatatctaga
    45061 tgaaaagcag caagaaatag aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat
    45121 aagagaagaa ctcaaaaaag caactgaaga aataacaaaa aatagtcagc tattgaaaga
    45181 acagacagaa caagcagaac agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct
    45241 tcagcttttt ttgcgtccag gggagccatg tcttgtttgt ggatcaacgg aacaccccat
    45301 acaacaatta aaacacgaac agccaaataa ggaagatatc ttaaaagtag aacaacaact
    45361 ggcagaagct gagtctgctg tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca
    45421 tgaaaataat cttcaacaac aattatcaga tttagaacaa aaaatcatgg caacgaatat
    45481 acaattggct gaacaagaag aacacttgca acaggctttg aaaaaggcat ttcctgagat
    45541 aacagaacaa aaaacaaaaa caactcttgt agtaatcgaa caatctttag atagacgaaa
    45601 aagcaagatg gccaatgcaa gaatagagct ggaagaaata agacaacaag cagaaaagct
    45661 cgaacaacaa ttagctgtct acaaacagca gcagacagaa aaaaataatc agctccagca
    45721 actgcaagga gaaatcaaaa gtttagaaca acaattgcaa gatacggata gtaactgttt
    45781 agaagaggag atacgacgac ttgaaaaaca gttagaagaa gactcgaatc aactagctgt
    45841 tgagcagaaa gcaggagtgc aattgttgca agatcttcat acgcttcgga cacagcttga
    45901 tcttcaacat gaacaaatag aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat
    45961 agctaaaaag ttagaaagcc agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc
    46021 acaacagcaa gcacaatata aagaaaacca acgtacagtt acttcttatc atgaagagca
    46081 attagtgaca gctgaccggc tgcgtcaatt agaaaatatc cagctaactg agacattccc
    46141 agatacagaa gagatcagcc aacagttaga agaaataaga cgtatgatcg aaataaagca
    46201 agaaaagata tacggtttac aagaacaaaa aattagtaat caaaaaatct acgatgaatg
    46261 tctttcgatt tatcacacaa gccagacgaa attagatgag cttacgcaat tacagcagct
    46321 ttcgcaaaca ttcaacggag aaaatcctaa gaagactagt ttggaacggt atgtgcttca
    46381 ggtttatctt caagaagtgt tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa
    46441 tcgttatcaa tttgagctag cggataccat tggcagttat cgagggaaaa ccggattaga
    46501 aatcaatatc tatgatgatc aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg
    46561 tgagagtttt attgcagcac tttctttagc attagctctt gccgatgtga tccagacaca
    46621 agctggtggt gtagcaatcg atgcattgtt tattgatgaa ggatttgggt cattagatga
    46681 agaagctttg gaaatggcaa tggaagcttt agaaacgatc gaaagtgaag gaagaatgat
    46741 cggcatcatt agtcatgtaa gagaattgaa agaacgagta ttacaacaaa taagaattga
    46801 tacagaaggt agcggacaaa gcaaaatacg ctatcaactt ggataaaaag ggagattggt
    46861 aactatgaaa tggagtattc cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga
    46921 aggccgagtg ttatcggttg tccctgacca agaagaaaac gtgtggcatg cagaagtctt
    46981 gggcagtgaa ttgtatatgg ttgatttgga tggtacagca aaagagatag attactgcca
    47041 atgtccctat tgggaggaac ataaatattg taagcataca gttgctgtgg aactttattt
    47101 acggtcgaaa aatctatctc gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa
    47161 agcaacaagt gagggagaaa tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa
    47221 tcctcaagcg gtgcaacctt tgattattga ataccaagta gaaacgattg agactaatca
    47281 gtatcaccca gagctttcta ttttggcact ttacttgcgt atcggttcat tggcatcacc
    47341 gaaaaaaaca tatatcgtaa aaaacatcta tgatttttta caagcttaca cagaaaaaga
    47401 aacttacact gttaataaac agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga
    47461 agatcaaaaa atactcacgc atcttgcagg aagtgctcag acgcatcaat tattaggtac
    47521 gaacggctta caagtcaaag gaaaactaga taaaagatat ctgcttctcc cagtagaaca
    47581 agcccgcttc ctgttagagc agatgaatca gactacacgt ttgcatctgc agataaatga
    47641 acaaaacgat caaggaatac aattttccga tcaaaacaaa cctttatcat tcaaagtgga
    47701 aaaatttgga gaagattatt tgctgcaagc attgaatgat tttgattttt tctttatgca
    47761 ttatcagtgg ggagttatcc aagggacatt ttattctctg acgaaatatc aacaaacggt
    47821 ttatcaaact tggaaacaat tgattcgccg attggagaaa ccagaagtag tgttcaagaa
    47881 aaaagaatta ccgtctttgt ttaaagagat tatccctctg ctgtcagaga tcggcgacgt
    47941 agctattgcc cctgcagtag aagaggaagt agcagatatc cccgtcgaat ttattttctt
    48001 tttccgaaaa gcaaaaggaa aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat
    48061 ctattcgact gacccgaagc atgaggtctc gacagaacag gcttttcagg tgttacgtga
    48121 cacagtagaa gagaaacgag tacttgatct attcagaatg tatcgctacc agaaaaatga
    48181 aactggttat gaacgtccat tgccaagcgg ggaagaacta tatgcctttt tccgcacaga
    48241 actatctgtc ttccgtcagt ttggtgaagt cagacttgga agaaaattgc gagagttgta
    48301 tttagatgcg cataaacatc aaccgaaaat cgaagtaacc gagaccggtt catggctcga
    48361 tattcgattc gatgtgacag ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt
    48421 gctgagaaat gatgcttttt atacattaga aaatggtcag gttctttctt ttgattcaga
    48481 agaatttcaa caaacaagcc aagtgttgca acaattacgg gaatcgatac gtacagaaga
    48541 aggaacgatc catgtaccta aaaatcaagg attgatcatt caaaatcaat tggaaaaaag
    48601 caatgctact tttagtgaat cgttccaaac gatggtacaa gatctcattc atccagaaag
    48661 ataccaggca cagcttccca aaggattgaa tgcaacgatg agagattatc aaaagcaagg
    48721 ttttcgatgg ttgaagatgt taggtcatta tcagtttggc ggtattttag ccgatgaaat
    48781 gggacttggg aaaacactac agacaattgc ctttttactt tcggaaaaag aagaacggaa
    48841 aagcttctct gctttgatcg tagcgcctgc gagcttaatt tacaactggc aggcagaggt
    48901 gagaaaattc gccccttctt taagtatcca agtaatcaat gggaataaaa aagaacgtga
    48961 agaattactg gctaaagaca cagatatccg agtgacttct tatgccagct taagacagga
    49021 tctagctaat tatcagtcgc aaaaaattga ttatttgatt cttgatgagg cacaaatggt
    49081 caaaaatagc agtacgaaaa ctgcacaagc attgagagaa ttagctgtac ctcagcggtt
    49141 tgcactgagt gggacaccaa tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac
    49201 gattatgcca ggatttttcc cgactaaaac aaaattcagg gaacttgccg cagaagaaat
    49261 tgcgcaaatg attcgaccgt ttattttacg gcgagataaa caaactgtgt tgaaagactt
    49321 gccggaaaaa acagagatga atctatattc tgcacttaca gaagaacaaa aaactgttta
    49381 tttagcttac ttgcgtcaaa tgcgtgaaga aatcacatca atggattctg aagcattcaa
    49441 gaaaaaccgg atcgggatac ttgctggtct gacaagactg cgacaaattt gctgcgatcc
    49501 tcgtctgttt attgaagatt accaaggcgg ttccggcaag ctcgaacaag taaaagatct
    49561 actggtagct gccaaagaga acaaacgaag agttttgctg ttttctcaat ttacagggat
    49621 gctgactatc ttgcaagaag agttagccga gctagggatc tcgacatttt atttaagagg
    49681 cagtacgaaa ccacaagatc ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga
    49741 tgtttttctg atttccttaa aggctggggg aactggattg aatctcacgg gagcagatac
    49801 ggtcatcttg tatgaccttt ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc
    49861 acatcggatc ggacaaaaaa atgtggtaga agtgtggcgt atgatctctg aaggaacgat
    49921 tgaggaacgc atggattcac tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca
    49981 aggtaatgaa gaacagttga cgaaactgac tgaagaagac atccgcatga ttttaagtgt
    50041 aggagaaatc gaggagtaag agactcgaaa aagcgttcag taatgggtaa gaaagccttt
    50101 ctaaagaagc gattgtttat ttgatttaaa aaatagcaag gaggctggga ttccatttta
    50161 tcccagcttc cttgctatca tttttttatt tctattttta aaggttatac aaagattgtc
    50221 ttcattgtct ctaacagctg atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt
    50281 tcaattttgc gttctcgatg gttgaaccaa agcgcttgcc agttagcact ttttgcacct
    50341 agaacatcat tgtcgtaatt atcgccaacg tataaggtct cttctggaag catatgaaat
    50401 tctttctcag ctagctgaaa aatctctttt tctggttttt ggaaacctgt tgcttgagaa
    50461 atgagcatat tgcgggaagg aatccaattg ttcaattgaa gttgcttcag tttttttgtc
    50521 tgatggtcag tcggcccatt tgtgataatt cctaatggga cattcttttc cttcaagaaa
    50581 tcgagggttt ttttgacctc ctcatgcaag cagatattat caagttcttc ctcgtaaatt
    50641 ttttgaaata agaggccatc ttcttccgta atatgagggt agtctaaatc ttttagtgat
    50701 tggctgatcc gatgtgctcg catatattct agtgtccaat ctcctgccat tacttttggg
    50761 aagttttcat cactatgatg gcggaaccgg atatatagtg gatgcatatc tgcatctgaa
    50821 acaagcggaa cgactctttt gaccgcgttt cgaaatggct gctgctgatc atacatcgta
    50881 tcatcaacat caaacacaac tgatttaatc aaaattttac acgcctttcg gttttcattg
    50941 attttttcac aaatccttga ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat
    51001 aaaggttttt cttactatat ttctatttcc ttgacagaat aaggttttta tatttcagtt
    51061 tttttcacta aaaatcgtga aacacgtcaa taagtttgat gaacaaatta atcattatgg
    51121 tagaagtcga ttgatttatt ttaatgcaat ctctgtggaa ttttcgaaag atttattttt
    51181 ttaatacagt ctcaatataa ctattcaaac ataaaataac gttatttgat ttatttgttt
    51241 atagtaaatt ttatttagta atcattgctt taaaatacta cgcttatata acagagaaaa
    51301 taagcgttat aataaagaac agtattattt aaaatgacag aaaacattac tattaaagaa
    51361 ataaaaaaca taaaaaatct taagaaatcg gtttcattta gcttttgaga taaaataata
    51421 gtacagtttt atacgctgtt tcatatgttt agaaaatttg aattagattt gaaaactcta
    51481 atttttaaat gataaaaaaa gcgagaatgc tggttttact gtatattaac cttagataac
    51541 tttcattttt ttaaaaaaat tatgaaaaaa aggtagctat ttaaaagttg attatgtata
    51601 atagaaacag atgggagatt attatgatct tctgttacaa aaaagtgatt cttatcacga
    51661 aaaggagtgg tgcacgttgt taacattata tacttcccca agttgtactt cctgcagaaa
    51721 ggctcgtgcg tggttgcaag aacatcagat tccatttgtt gaacgtaata ttttttcaga
    51781 accattgaac agttctgaat taaaagcgat tttacaaatg acagaagacg gaacagaaga
    51841 aatcatctcg acacgttcca aagtattcca aaaactgaac atggatttag atgatctgcc
    51901 gttacaagaa ttattggaac ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat
    51961 gattgatgat aaacgtctgc aagttggttt taatgaagat gaaattcgtc ggttcctacc
    52021 gcgcgatgta cgacaattag aattacgtca agcacaattg atggctggat tatagaagga
    52081 taatacgaaa cttggaaaag actattacaa agatagtttt tccaagtttt tttgttttta
    52141 caaaaagtat tcttgattag atgtataaaa aggtagtaga agatgatgat tgcacgaaaa
    52201 atagagaggg aaaattagct gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta
    52261 tagttaaata agatagcttg aaaggttgaa aaatccgctg gttttattaa attcgcttaa
    52321 cagcgagatt ttttttcttt acatttaagc tgatttcgct acaatgaatc tatattaaac
    52381 attgtggcaa agtgaggtgt agcaaaatgg aaatggaaca tattaatgaa aatacgatcc
    52441 gtgtactaat tggtcatgaa gatttagagg aacggggcgt ttcatttttg gatttacttg
    52501 gcaatcacaa agaaatcgaa aatttctttt atagtatttt ggaagaagtt gatatcgaag
    52561 aggagttccg aggaagcgaa gctgtcactt tccaagtttt gccaaaagga gacggattag
    52621 aactgtttat cagtaaaaat cttccggatg aagaaatttc tcaatcagaa gattctactg
    52681 ttgattcaga agatgtgagt gactttcttc gtcagcagat tattggcagc gatccggagg
    52741 aagaattatc tggaagcgcc ctagaagaac aggaaagaca agcaactttt gcttttgaag
    52801 attttgaaca agtgatccaa cttgcaacag atgtcgaact agagtctgct tggactgatt
    52861 tgtatttatt cgaagagcgc tattacctag tcgttcactt ctggatggaa aatctcaacc
    52921 aagcggatgt agagaatcag attgctcgaa ttttggagtt tgctgaaaag agcgatcgta
    52981 caccagaaac attgaatgaa tatggacaat gtctgatggc gcgtaatgct atcgagcgaa
    53041 cgaaatttta ttttgtataa atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg
    53101 cagtcttttt ttcgtataaa tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca
    53161 aacgaaaaat attgggaact atttttgttt agctgttctt attacttgat gcagaatagc
    53221 tttttcacgc cctctttttt cgtgtaaata aattcttaga cgtaaataag ttcagaggga
    53281 gaaaaatgct gcttgcaatg aatgaatata ataagtgctg ttttgctaaa catgcagaaa
    53341 aaggaaagaa atattattgt cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga
    53401 aaaaatgtgc tcattttgcc catcaaaaat cagataactg ttcggtcttt agtgaaagag
    53461 aatcaaaaga gcacttacag ttaaaggaat gcttcatgga ttggctggga cagtcagtag
    53521 aaccagtatt tttggaagcc tatttgccga ggttgcggca aaggccggat attttgttgg
    53581 cgaatctagc aatagaaatc caatgttcta gactgtctca ccagagattt attgaaagaa
    53641 cccaaaatta tttgaataac agttaccaag tatggtggat acttggtaat tcttttcttg
    53701 gacaatcgca attctcattg atagaaaaaa gttgctgcta ctataataga aaaagaggag
    53761 tgcattgctg gaaagctgat ctcaagaaac aaaagcttta tttgtatcat catattacag
    53821 agactgtatc agggcatatt tccttttgca gtagctgctg gactttttct agtagggacc
    53881 ttaaagaaat attcactagt aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag
    53941 tgagtgaaga tgggaagaaa tggctgacac gccaacttat tcacaagcaa aagaatacag
    54001 tatccataca agaacaatgc tacttgcgtc ataaacatct tttgcatcta tcatcgtgga
    54061 tctatcaaaa aagtcggttt ttcttttatt tacaagaaca ggtttttctt tatcgaatgt
    54121 tgtacgaaga agccttggaa aaccagaaag ttcctgattt caactcatgg ctttgccaaa
    54181 taaaagaaca taaaagggaa tggctttttc ctatgattga tgaagagatg gtctatcagc
    54241 agttttttaa cgaatgcata cacttgtctt ctttgaaaaa atagtaagta taaaaatagg
    54301 ctaggaatcg gttttctatg taaaacaaga tttagttatg ctaaaattga tggaagcaga
    54361 cacatgaatg agtagaaaag ttagatgctg tgacatgtgg atgttagact atgatctatt
    54421 ttgatagata gagctaaggg aagaaaagga gtggatttca tggaagtaaa gcagttgcca
    54481 aaacgagaag aattgcctga aaatttaact tgggacttga ccaagatctt ttcaagcgac
    54541 caagagtttg atgagaaata tttggaatta tcagaagagt taaaacaatc tgaaaaacac
    54601 aaaggaacac ttgatcaagg cgcttctcaa tttttaaatg cgattgaatt cgtattgagg
    54661 gtttatcgcc aaactgaagt catttatgta tatgcgcacc ttaaaaacga tcaagacact
    54721 ggaaatacag attaccaagc gctttatgca agagcaagca gtctgttttc gaaagttagt
    54781 gaagccgttt cctggtttga accagaaata ttgcaattgt cagatgacca gatttggcaa
    54841 tatttcaaag aagaaccaaa attggaagtc tatcgccatt atatccagca aatagtagat
    54901 aatcgagccc atgtcttatc tgctgagcag gaatctcttc ttgctggagc aggtgaaatc
    54961 tttgatgctt caagtgatac atttgctgtt ttgaataatg cagatctagt ttttccaacg
    55021 attgaaggag aaaatggtga aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta
    55081 gaaagcacgg atcgaagggt gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa
    55141 caatttagaa atacatttgc ttctacttta ggcacacata taaaaggaca taattttaaa
    55201 gcgaaagtcc gtaattacag ctctgccaga gaagcgtctt tgagcaataa tcatattcct
    55261 gaaagtgtat acgatacttt ggtagacgtg gtaaacaagc atttgccttt gttacatcga
    55321 tacatggaat tacggaaacg tttattagaa gtggaaaaac tgcacatgta tgatctttat
    55381 acaccggtct taggggaagc tccaattacc tttacgtacg aagaagcaaa agaaaaagct
    55441 ttagaagcac tgaaaccaat gggtgaagaa tacatggcca tcgtagaaaa agcattctct
    55501 gaacgttgga tcgatgttgt cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga
    55561 agctatgaca caaatccata tattttattg aattggcatg atacgctgga tcagctattt
    55621 acgcttgtcc acgaaatggg acatagtgtt catagttatt tcactcgttc gaaccagcct
    55681 tatgtgtacg gcgactactc catcttttta gcagaaattg cttcgacaac gaatgaaaat
    55741 atcctaacgg agtatttatt ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc
    55801 aaccattact tggatgggtt taaaggaaca gttttccgcc agacacaatt cgctgaattc
    55861 gagcatttca tgcatacgga agatgaaaaa ggtgtgccat tgactagtga atacctaagt
    55921 gatagttatg gtaaattgaa tgcaaaatat tatggtccag cagtcgaaga agacccagaa
    55981 attaaattcg aatggtcacg gataccgcat ttttattata attactatgt tttccaatac
    56041 tcgactggct tttctgctgc ttcagcactg gcgaagaaaa tactaaacca ggaaccagag
    56101 gcactagaga actacttggc ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta
    56161 atgaaaaaag caggagttga tatgacacag gctgcatata ttgaagatgc aatgtcgatg
    56221 tttgaacaac gtctaaatga attagaagaa ttgatcgatc gtttataagg ctttctattt
    56281 ttgattttct cgaatagaaa cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt
    56341 attttttta
//
LOCUS       DAIGQM010000014        54513 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.014, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000014 DAIGQM010000000
VERSION     DAIGQM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.014"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            262..570
                     /gene="rpsJ"
                     /locus_tag="NOA48_000770"
     CDS             262..570
                     /gene="rpsJ"
                     /locus_tag="NOA48_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCI0789055.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            601..1230
                     /gene="rplC"
                     /locus_tag="NOA48_000771"
     CDS             601..1230
                     /gene="rplC"
                     /locus_tag="NOA48_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCI0789056.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            1258..1881
                     /gene="rplD"
                     /locus_tag="NOA48_000772"
     CDS             1258..1881
                     /gene="rplD"
                     /locus_tag="NOA48_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCI0789057.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            1881..2171
                     /gene="rplW"
                     /locus_tag="NOA48_000773"
     CDS             1881..2171
                     /gene="rplW"
                     /locus_tag="NOA48_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCI0789058.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            2210..3043
                     /gene="rplB"
                     /locus_tag="NOA48_000774"
     CDS             2210..3043
                     /gene="rplB"
                     /locus_tag="NOA48_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCI0789059.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            3086..3364
                     /gene="rpsS"
                     /locus_tag="NOA48_000775"
     CDS             3086..3364
                     /gene="rpsS"
                     /locus_tag="NOA48_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCI0789060.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            3387..3734
                     /gene="rplV"
                     /locus_tag="NOA48_000776"
     CDS             3387..3734
                     /gene="rplV"
                     /locus_tag="NOA48_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCI0789061.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            3748..4404
                     /gene="rpsC"
                     /locus_tag="NOA48_000777"
     CDS             3748..4404
                     /gene="rpsC"
                     /locus_tag="NOA48_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCI0789062.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            4407..4841
                     /gene="rplP"
                     /locus_tag="NOA48_000778"
     CDS             4407..4841
                     /gene="rplP"
                     /locus_tag="NOA48_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCI0789063.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            4831..5019
                     /gene="rpmC"
                     /locus_tag="NOA48_000779"
     CDS             4831..5019
                     /gene="rpmC"
                     /locus_tag="NOA48_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCI0789064.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOA48_000780"
     CDS             5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOA48_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCI0789065.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            5368..5736
                     /gene="rplN"
                     /locus_tag="NOA48_000781"
     CDS             5368..5736
                     /gene="rplN"
                     /locus_tag="NOA48_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCI0789066.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            5773..6081
                     /gene="rplX"
                     /locus_tag="NOA48_000782"
     CDS             5773..6081
                     /gene="rplX"
                     /locus_tag="NOA48_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCI0789067.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            6109..6648
                     /gene="rplE"
                     /locus_tag="NOA48_000783"
     CDS             6109..6648
                     /gene="rplE"
                     /locus_tag="NOA48_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCI0789068.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            6667..6852
                     /locus_tag="NOA48_000784"
     CDS             6667..6852
                     /locus_tag="NOA48_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCI0789069.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            6888..7286
                     /gene="rpsH"
                     /locus_tag="NOA48_000785"
     CDS             6888..7286
                     /gene="rpsH"
                     /locus_tag="NOA48_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCI0789070.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            7318..7854
                     /gene="rplF"
                     /locus_tag="NOA48_000786"
     CDS             7318..7854
                     /gene="rplF"
                     /locus_tag="NOA48_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCI0789071.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            8015..8371
                     /gene="rplR"
                     /locus_tag="NOA48_000787"
     CDS             8015..8371
                     /gene="rplR"
                     /locus_tag="NOA48_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCI0789072.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            8392..8892
                     /gene="rpsE"
                     /locus_tag="NOA48_000788"
     CDS             8392..8892
                     /gene="rpsE"
                     /locus_tag="NOA48_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCI0789073.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            8907..9086
                     /gene="rpmD"
                     /locus_tag="NOA48_000789"
     CDS             8907..9086
                     /gene="rpmD"
                     /locus_tag="NOA48_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCI0789074.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            9130..9570
                     /gene="rplO"
                     /locus_tag="NOA48_000790"
     CDS             9130..9570
                     /gene="rplO"
                     /locus_tag="NOA48_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCI0789075.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            9570..10865
                     /gene="secY"
                     /locus_tag="NOA48_000791"
     CDS             9570..10865
                     /gene="secY"
                     /locus_tag="NOA48_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCI0789076.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            10927..11574
                     /locus_tag="NOA48_000792"
     CDS             10927..11574
                     /locus_tag="NOA48_000792"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCI0789077.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            11765..11983
                     /gene="infA"
                     /locus_tag="NOA48_000793"
     CDS             11765..11983
                     /gene="infA"
                     /locus_tag="NOA48_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCI0789078.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOA48_000794"
     CDS             12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOA48_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCI0789079.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            12150..12515
                     /gene="rpsM"
                     /locus_tag="NOA48_000795"
     CDS             12150..12515
                     /gene="rpsM"
                     /locus_tag="NOA48_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCI0789080.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            12543..12932
                     /gene="rpsK"
                     /locus_tag="NOA48_000796"
     CDS             12543..12932
                     /gene="rpsK"
                     /locus_tag="NOA48_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCI0789081.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            13012..13950
                     /locus_tag="NOA48_000797"
     CDS             13012..13950
                     /locus_tag="NOA48_000797"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCI0789082.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            13978..14358
                     /gene="rplQ"
                     /locus_tag="NOA48_000798"
     CDS             13978..14358
                     /gene="rplQ"
                     /locus_tag="NOA48_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCI0789083.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            14630..15469
                     /locus_tag="NOA48_000799"
     CDS             14630..15469
                     /locus_tag="NOA48_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0789084.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            15445..16314
                     /locus_tag="NOA48_000800"
     CDS             15445..16314
                     /locus_tag="NOA48_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0789085.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            16304..17101
                     /locus_tag="NOA48_000801"
     CDS             16304..17101
                     /locus_tag="NOA48_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0789086.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            17304..18050
                     /gene="truA"
                     /locus_tag="NOA48_000802"
     CDS             17304..18050
                     /gene="truA"
                     /locus_tag="NOA48_000802"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0789087.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(18383..21052)
                     /locus_tag="NOA48_000803"
     CDS             complement(18383..21052)
                     /locus_tag="NOA48_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCI0789088.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(21290..21478)
                     /locus_tag="NOA48_000804"
     CDS             complement(21290..21478)
                     /locus_tag="NOA48_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCI0789089.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            21748..22110
                     /locus_tag="NOA48_000805"
     CDS             21748..22110
                     /locus_tag="NOA48_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0789090.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            22162..23844
                     /locus_tag="NOA48_000806"
     CDS             22162..23844
                     /locus_tag="NOA48_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCI0789091.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            23961..25997
                     /gene="recG"
                     /locus_tag="NOA48_000807"
     CDS             23961..25997
                     /gene="recG"
                     /locus_tag="NOA48_000807"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCI0789092.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            26046..27047
                     /gene="plsX"
                     /locus_tag="NOA48_000808"
     CDS             26046..27047
                     /gene="plsX"
                     /locus_tag="NOA48_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCI0789093.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            27169..27411
                     /gene="acpP"
                     /locus_tag="NOA48_000809"
     CDS             27169..27411
                     /gene="acpP"
                     /locus_tag="NOA48_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0789094.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            27679..28683
                     /locus_tag="NOA48_000810"
     CDS             27679..28683
                     /locus_tag="NOA48_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789095.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            28684..29628
                     /locus_tag="NOA48_000811"
     CDS             28684..29628
                     /locus_tag="NOA48_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789096.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            29628..30590
                     /locus_tag="NOA48_000812"
     CDS             29628..30590
                     /locus_tag="NOA48_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789097.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            30617..31531
                     /locus_tag="NOA48_000813"
     CDS             30617..31531
                     /locus_tag="NOA48_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789098.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            31557..33338
                     /locus_tag="NOA48_000814"
     CDS             31557..33338
                     /locus_tag="NOA48_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0789099.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            33686..34372
                     /locus_tag="NOA48_000815"
     CDS             33686..34372
                     /locus_tag="NOA48_000815"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCI0789100.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            34392..37973
                     /gene="smc"
                     /locus_tag="NOA48_000816"
     CDS             34392..37973
                     /gene="smc"
                     /locus_tag="NOA48_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCI0789101.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            37982..38791
                     /locus_tag="NOA48_000817"
     CDS             37982..38791
                     /locus_tag="NOA48_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0789102.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            38802..39800
                     /gene="ftsY"
                     /locus_tag="NOA48_000818"
     CDS             38802..39800
                     /gene="ftsY"
                     /locus_tag="NOA48_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCI0789103.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            39987..42254
                     /gene="gshAB"
                     /locus_tag="NOA48_000819"
     CDS             39987..42254
                     /gene="gshAB"
                     /locus_tag="NOA48_000819"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCI0789104.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(42343..42795)
                     /locus_tag="NOA48_000820"
     CDS             complement(42343..42795)
                     /locus_tag="NOA48_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCI0789105.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            42945..43895
                     /locus_tag="NOA48_000821"
     CDS             42945..43895
                     /locus_tag="NOA48_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0789106.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            43888..44847
                     /locus_tag="NOA48_000822"
     CDS             43888..44847
                     /locus_tag="NOA48_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0789107.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            44844..45599
                     /locus_tag="NOA48_000823"
     CDS             44844..45599
                     /locus_tag="NOA48_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789108.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            45622..46575
                     /locus_tag="NOA48_000824"
     CDS             45622..46575
                     /locus_tag="NOA48_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0789109.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(47219..47515)
                     /locus_tag="NOA48_000825"
     CDS             complement(47219..47515)
                     /locus_tag="NOA48_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCI0789110.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            47870..48226
                     /locus_tag="NOA48_000826"
     CDS             47870..48226
                     /locus_tag="NOA48_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0789111.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            48236..49135
                     /locus_tag="NOA48_000827"
     CDS             48236..49135
                     /locus_tag="NOA48_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCI0789112.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            49652..50383
                     /locus_tag="NOA48_000828"
     CDS             49652..50383
                     /locus_tag="NOA48_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0789113.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            50528..52555
                     /locus_tag="NOA48_000829"
     CDS             50528..52555
                     /locus_tag="NOA48_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI0789114.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            52663..53760
                     /locus_tag="NOA48_000830"
     CDS             52663..53760
                     /locus_tag="NOA48_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0789115.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            54067..>54513
                     /locus_tag="NOA48_000831"
     CDS             54067..>54513
                     /locus_tag="NOA48_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789116.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        18213 a         9637 c        11691 g        14972 t
ORIGIN      
        1 aaaagagtca gtattttcta aatgaaactt tatgaaaaca aaatgttttt tacaagaaaa
       61 agccttgctt tgtgagttta tatatattat aatgacaaag gtgcgtttac tttagtgaat
      121 tgcacagacg taatcagaat gatttcgtcg gctaagaaac gagaggttgc gacacgcccg
      181 gacgctttgc cacgaacgag cgtgacggaa attttcgtgg agctatgtct acttttcaaa
      241 ataggcgaag gagggaacaa gatggcaaaa caaaaaattc gtatccgttt aaaagcgtat
      301 gaacaccgta ttttagatca atcagcggat aaaatcgtgg aaactgcaaa aagaactgga
      361 gctagcgtgt ctggtccaat tccattacca actgaacgca gtctttacac aatcatccgt
      421 gcgactcata aatacaaaga ttcacgcgaa caattcgaaa tgcgtacaca caaacgtctt
      481 atcgacattg tgaacccaac accaaaaact gttgatgctt tgatgaagct agacttacca
      541 tctggtgtaa acatcgaaat caaattataa aactaaaaca aaaataatgg aggtgtactc
      601 atgaccaaag gaatcttagg gaaaaaagtg ggaatgacac aaatcttcac tgaatctggt
      661 gaattaattc cagtaactgt tgtagaagct actccaaacg tagtactaca agtgaaaaca
      721 atggaaacgg atggctacga agctattcaa gttggttacc aagatatgcg tgaagtttta
      781 tcaaacaaac ctgcgaaagg tcatgttgca aaagcaaaca cggctcctaa gcgcttcatt
      841 cgtgaattca aaaatgttga gctaggagaa tatgaagtag gaaaagaaat tacagtagat
      901 gttttccaag caggagacat tattgatgta acaggtacta cgaaaggtaa aggattccaa
      961 ggggttatca aacgccacgg acaaagccgc ggaccaatgg ctcacggttc tcgttaccat
     1021 cgtcgtcctg ggtcaatggg tccagttgca cctaaccgtg tatttaaaaa caaacgtctt
     1081 gctggccgta tgggtggcaa ccgcgtaact atccaaaact tggaagttgt acgtgtcgat
     1141 gcagaaagaa atgttatctt gatcaaaggt aatgttcctg gagctaaaaa atctttaatt
     1201 actatcaaat cagctgtgaa agctaaataa ttgtaggaag aaaggaggaa ctaaggaatg
     1261 ccgaatgtag cattattcaa acaagatgga agccaaaacg gtgaaatcac acttaacgaa
     1321 gaaatcttcg gaattgaacc taatgaaagt gttgtttacg atgcaatcgt aatgcaacgt
     1381 gcgtcattaa gacaaggaac acacgcggtt aaaaaccgta gcgctgttcg cggcggcgga
     1441 cgtaaaccat ggcgtcaaaa aggaacaggt cgtgcacgtc aaggatctat ccgctcacca
     1501 caatggcgtg gaggtggcgt agtctttgga ccaacaccac gttcttacag ctacaaactt
     1561 cctaaaaaag ttcgtcgttt agcaatgaaa tctgtattgt cagaaaaagt tgctgaaaac
     1621 aacttggtag caatcgaagg cttgaacttc gacgcaccaa aaacaaaaga attcaaacaa
     1681 gttcttgcta acttatctat cgactctaaa gtattggttg ttctagaaaa aggtaacgac
     1741 tttgctgctt tatcagcacg taacttacca aacgtttctg tagtaacttc tgataatgtg
     1801 agtgtgctag acgttgtatc aaatacaaaa gtgttagcaa cacaaactgc tcttactcaa
     1861 attgaggagg tgcttgcata atgaacttac tagacgtaat caaacgccca gtgatcactg
     1921 aaaaatcaat gcttgccatg gatgacaaga aatacacttt tgaagtggac actcgcgcaa
     1981 acaaaacttt agtaaaacaa gcggtagaag ctgcttttga cgttaaagtc aaaaacgtga
     2041 acatcgtgaa cgtacgtgcg aaattcaaac gtatgggcaa atatgcagga tatacaaaaa
     2101 aacgtcgcaa agcgatcgtt acattgactg aagattcaaa agaaatccaa ttattcgaag
     2161 ctgctgaata agcactaata gataactcat taaattagga gggaaaaacg tggcgattaa
     2221 aaagtacaaa cctacctcaa atggtcgtcg taacatgaca ggttctgatt ttgctgaaat
     2281 cacaacatca acacctgaaa aatcattgtt acaaccattg aaaaaccatg ctggacgtaa
     2341 caacaacggc cgcatcactg tacgtcatca aggtggcgga cacaaacgcc aatatcgcgt
     2401 gatcgacttc aaacgtaaca aagataacgt tgttgcaact gttcaaacga tcgaatatga
     2461 tccaaaccgt tcagctaaca tcgcgttagt acactatgaa gatggagtga aagcttacat
     2521 cttagcacct aaaggactag aagtgggtat gaaacttgtt tcaggtccag aagcagatat
     2581 caaagtcgga aatgctcttc cattagaaaa cattccagtt ggtactgtta tccacaacat
     2641 tgaaatgaaa cctggtaaag gtggacaatt gatccgttct gctggtacaa gtgctcaagt
     2701 acttggtaaa gaaggcaaat acgtattgat ccgcttgaac tctggtgaag ttcgtatgat
     2761 cttagctgca tgccgtgcta caatcggttc tgtaggtaac gaacaacacg aattaatcaa
     2821 catcggtaaa gctggacgct ctcgttggat gcgtaaacgc ccaactgtac gtggtagcgt
     2881 aatgaaccct aatgatcacc cacacggtgg tggtgaaggt aaagctccta tcggacgtaa
     2941 agcaccagtt tctccttggg gtcaaccagc tcttggttac aaaactcgta acaaaaaagc
     3001 taaatcagac aaacttattg ttcgtcgtcg caaaaataaa taattacttt gaccatgtgt
     3061 cgcacatttt gagaggaggt tcaccatggg tcgtagttta aagaaaggac cttttgtcga
     3121 tgagcattta atgaaaaaag ttgaagctca agcaggggtt gaaaagaaaa aagttatcaa
     3181 aacttggtca cgccgttcaa cagttttccc aagttttgtt ggatatacca tcgcagttta
     3241 tgatggacgt aaacatgtac cagtttacat ccaagaagac atggtaggac acaaattagg
     3301 tgaatttgca cctacaagaa cttatcgtgg acatgctgct gacgataaga aaacgaaacg
     3361 ctaatttgag gggaggataa atccaaatgg cagaacaaat cacatcagct aaagcaactg
     3421 caaaaacagt tcgcacttca cctcgaaaag cccgtttagt aattgacctt atcagaggta
     3481 aaagtgtcgc agatgcaatt tcaatcttga aattcacacc aaacaaatct gctggaatca
     3541 ttgaaaaagt attgatgtca gcagttgcga atgcagaaaa taactttgac ttagatgttg
     3601 aaaacttggt agtaagcgaa gcttttgtta acgaaggacc tacaatgaaa cgtttccgtc
     3661 ctcgtgcaaa aggatcagct tctccaatca acaaacgtac aagtcatatc acggtagtcg
     3721 tatcagaaaa ataaggaggg ataatcagtg ggtcaaaaag tacatccaat tggaatgcgt
     3781 gtaggcatca tccgcgactg ggatgctaaa tggtatgctg aaaaagagta tgctgagttc
     3841 ttacacgaag atttaagaat ccgtaaattt atttcaacta aacttgctga tgctgctgta
     3901 tcaacagttg aaatcgaacg cgcaacaggt cgcgtaaaca tttcaattca cacagctaaa
     3961 ccaggtatgg ttattggtaa aggcggttct gaagtcgaaa gcctaagaaa agaattaaac
     4021 aaattaactg gtaaaagaat ccatatcaat atcgtggaaa tcaaaaaacc agatctagat
     4081 gcaaaattag taggtgaagg aatcgcacgt caattagaaa accgtgttgc tttccgtcgc
     4141 gctcaaaaac aagccatcca acgctcaatg cgtgctggcg ctcaagggat caaaactcaa
     4201 gtatctggtc gtctaaacgg agcagatatc gctcgttcag aaggatactc agaaggaact
     4261 gttcctcttc atactttacg tgcggacatt gattacgcat gggaagaagc agatacaaca
     4321 tacggaaaac taggagttaa agtgtggatc tatcgtggag aaattcttcc aactaaaaaa
     4381 aacactgaga aaggagggaa ataatcatgt tagtacctaa acgtgtaaaa caccgtcgtg
     4441 aattccgcgg aaaaatgcgc ggggaagcta aaggcggaaa agaagtagca ttcggtgaat
     4501 acggtttgca agctgttgat tcacattgga tcacaaaccg ccaaatcgaa gctgctcgta
     4561 tcgcaatgac tcgttacatg aaacgtggtg ggaaagtatg gattaaaatt ttccctcaca
     4621 aatcttatac tgccaaagca attggggtac gtatgggttc tggtaaaggg gcacctgaag
     4681 gatgggttgc accagtaaaa cgtggtaaaa tcatgtttga aatcgcaggc gttcctgaag
     4741 aagtagctcg tgaagcgtta cgtctagctt ctcacaaatt accaatgaaa actaagatcg
     4801 taaaacgtga ggaaatgggt ggtgaatcga atgaaggtta aagaaatcag agaattaacc
     4861 actgccgaaa tgcttgatca agaaaaacaa ttaaaagaag aattgtttaa tcttagattc
     4921 caattagcaa caggtcaatt agaaaacact gcacgtatta aagaagtacg taaatcgatt
     4981 gcacgcatca aaactgtgtt gcgtgaacaa gctaagtaat tatggaagga ggccattaag
     5041 cgtatgactg aaggaagaaa tcaacgcaaa gtttatcaag gtcgcgtggt ttcagacaaa
     5101 atggataaaa caattaccgt tgctgtcgaa acaaagaaaa accaccctat ctatggcaaa
     5161 cgcatgaact attctaagaa atacaaagtg catgatgaaa acaacacagc aaaagttggc
     5221 gacatcgtga gaattatgga aactcgtcca ttatcagcta caaaacgttt ccgtttgttg
     5281 gaagtagtcg aagaagcagt tattatctaa taacacgaga ttttcctata tagattgaat
     5341 gcaaaatctg aaaggaggat acacaacgtg atccaagcag aaagtcgttt aaaagtcgct
     5401 gataactcag gcgcacgtga aattttgacg atcaaagtcc ttggtggatc tggtcgtaaa
     5461 actgctaaca tcggtgatgt gatcgttgct acggttaaac aagcaacgcc aggtggggtt
     5521 gtcaaaaaag gtgacgtcgt taaagccgtt atcgttcgaa caaaatcagg agctcgtcgt
     5581 acagacggtt catatattaa atttgatgaa aatgctgcag tgattattcg tgatgataaa
     5641 agccctcgtg gaacacgtat ctttgggcca gttgcacgtg aactacgtga aaacaacttc
     5701 atgaagatcg tttcactagc accagaagtt ttataatctt gagacactta tcaaaggagg
     5761 tgcgaaacag ttatgtttgt taaaaaaggc gataaagtta aagttatcac tggaaaagac
     5821 aaaaacaaag aaggcgttgt actagcagcg ttcccgaaaa aagataaagt tattgtcgaa
     5881 ggtgtaaatg tcgttaaaaa acaccaaaaa ccttctcaag ctgctcctca aggtggaatt
     5941 gttgagatgg aagcgccaat tcatgtttct aacgtgatgg tggttgactc tactggtgta
     6001 gctggccgag ttggctacaa agaagtagac ggcaaaaaag tccgtgtttc taaaaaaacc
     6061 ggtgaagttt tagataaata aaagtttaag gaaggagggt cttactgaat gaaccgccta
     6121 aaagaaaaat atcttaaaga agtaactcca tcattgatgg aaaaatttaa ctatagctct
     6181 gttatgcaaa cacctaaagt tgaaaaaatc gtcatcaaca tgggtgttgg tgatgcggta
     6241 tcaaacgcta aaaacttaga taaagcagtt gaagaattaa ctttgatcac tggtcaaaaa
     6301 ccaatgatta caaaagctaa aaaatcaatc gctggattcc gtttacgtga aggaatgcca
     6361 attggtgcaa aagttacatt gcgcggagaa agaatgtacg aattcttaga caaattggtt
     6421 tctgtttcac taccacgtgt acgtgacttc catggtgtaa gtaaaaaagc ctttgacggt
     6481 cgtggaaact atactttagg tattaaagaa caattgatct tcccagaagt agattatgat
     6541 ttagtagata aagtacgtgg tatggacatc gttattgtaa caacagcaaa ctctgatgaa
     6601 gaatctcgtg agttgttgac acaattaggc atgccattcc aaaaataatt aaaggaggcg
     6661 aactacgtgg ctaaaaaatc aatgattgct aaaaacaaac gtcctgcaaa attttcaaca
     6721 caagcttata ctcgttgcga acgttgcgga cgtccacatt cagtttatcg taagttccat
     6781 ctttgccgta tttgcttccg cgaacttgcc tataaaggtc aaattcccgg cgtgaagaaa
     6841 gctagctggt aaaaagtaaa ttcgcataag aaggaggtaa aagatcaatg gtcatgacag
     6901 atccaattgc agattttcta actcgtatcc gtaacgcaaa catggttaaa catgagtctt
     6961 tagaagtacc tgcatcaaaa attaaacgtg acatcgctga aatcttgaaa cgtgaaggtt
     7021 tcgttcgtga tgttgaatac atcgaagatg acaaacaagg cgtgatccgt gttttcctaa
     7081 aatttggtaa aaacggcgaa cgtgttatca caaacttaaa acgtatctct aaaccaggtt
     7141 tgcgtgctta tgtcaaagct gacgaagtac caaaagtatt gaacggttta ggtatcgcaa
     7201 tcatttcgac ttctgaaggt gttgtcactg ataaagaagc tcgtgaaaaa aatatcggcg
     7261 gcgaagttat cgcttacgta tggtaatcaa gtagaatcta caaggaggtg tctttaagtg
     7321 agccgtatcg gaaataaagt cgttgttatc cctgaaggag taacagttac tcaagacgga
     7381 aacaacgtta cagttaaagg accaaaaggt gaattgactc gtactttttc agcagatatc
     7441 aaaatgaata tcgaaggaaa cgaagtaact ttcactcgtc caaacgacag taaagaaatg
     7501 aaaacaattc atggaacaac tcgtgcgaac ttcaacaaca tggttgtagg tgtcagcgaa
     7561 ggtttccaaa aagcgttaga actaatcggg gttgggtacc gtgcacaatt acaaggatca
     7621 aaacttgtat tgaacgttgg ttactcacat ccagtagaaa tcacaccacc agctggagta
     7681 actgttgaag taccagctaa cacacaagta attgttaaag gtgcgaacaa agaagaagtt
     7741 ggcgaattag ctgcaaacat tcgtggaact cgtcctccag aaccttataa aggtaaaggt
     7801 attcgttatg ttggcgaata tgtacgccgt aaagaaggta aaactggtaa ataatcgttt
     7861 agaaaaattg catagaagcc agcagcagga aaaaggcatt tggctgaagt ttaccttcaa
     7921 aaaaatacat ttttacttgt gccgcagctt ctatttttcg aaacgtattt actgcttgaa
     7981 atagtagtac aataaaaata aagaggtgac aattgtgatt acaaaaccag ataagaacaa
     8041 aacacgtcaa aagagacatc gtcgtgtacg taacaatatc tctggtactg ctgagcgccc
     8101 acgcttgaac gtttttcgtt ctaacaaaaa catctacgct caaattattg atgacgtagc
     8161 gggtgtaacg ctagcaagtg cctctacctt ggataaagaa atttcaggtg gaacaaaaac
     8221 agaagcagca caagctgtcg gtaaactagt tgctgaacgt gcagctgaaa aaggcattaa
     8281 agtagtagtc tttgaccgtg gtggatacct ttaccatggc cgtgtgcaag ctttagctga
     8341 agctgctcgc gaaaatggac tagaatttta gaagaaggag gaataccatt catggtttat
     8401 atcgatccaa aacatttgga attagaagac cgcgttgttg caattaaccg tgtaacaaaa
     8461 gttgttaaag gtggacgtcg tctacgtttt gctgctttag ttgttgtcgg tgacaaaaac
     8521 ggacacgtag ggtttggtac aggtaaagct caagaagttc ctgaagcaat ccgtaaagca
     8581 attgaagatg cgaagaaaaa cttagttgaa gtacctatgg ttggttcaac aatcccacac
     8641 gaagtaatcg gtgcttttag tggtggtaga atcctaatga aacctgctgt agaaggttct
     8701 ggggttgctg ctggtggacc agttcgtgcc gtattagaat tagctggggt agcagatatc
     8761 acttctaaat ctttaggctc aaatacacca atcaacgttg ttcgcgcaac agttgaaggt
     8821 ttgaaacaat tgaaacgtgc agaagaagtt gcagaacttc gcggcaaatc agttgaagaa
     8881 ttaatcggat aaggaggaca acaataatgg ctgaattaaa agttacttta aaacgcagta
     8941 ttatcggacg tcctcaaaac caacgcgata cagttaaagc gttaggtctt acaaagatta
     9001 acagttcagt ggttaagcct tctaatgaag caattaaagg catgatcaat actgtttctc
     9061 acctagtgga cgttgaagaa atttaattta gaaaaatcat aactagaaca ttaaggaggt
     9121 gccaaaccta tgaaacttca tgaattaaaa cctgctgaag gttcacgcca agtacgtaac
     9181 cgtgttggtc gtggtacttc atctggtaac ggaaaaactg ccggacgcgg acaaaaagga
     9241 caaaaagctc gttcaggcgg cggtgtgcgt ttaggatttg aagggggaca aacaccattg
     9301 ttccgtcgtt taccaaaacg aggattcaca aacgtgaacc gtaaagacta tgcagtcatt
     9361 aatcttgatg tattgaaccg ctttgaagac ggagctgaag taactcctgt tgctttagtt
     9421 gaagctggaa tcgtgaaaaa cgaaaaagct ggaatcaaag tattagctaa tggggaacta
     9481 aacaagaaat taactgtgaa agcagcaaaa ttctctaaag cagctcaaga agcaattgaa
     9541 gcggctggtg gatcaatcga ggtgatctaa tgtttagact attaaaagat gcttttaaag
     9601 taaaagacat tagatcgaaa atcctattta ctgtatttgt gttgtttgta tttcgcctag
     9661 gtgcacatat tactgtacca ggcgtaaatg ctgcttcatt gcaaaacctt tcttctttgc
     9721 catttttcaa catgttgaac ttggtaagtg gtagtgcgat gcaaaacttt tccattttct
     9781 caatgggggt ttcaccatac attactgctt ctatcgtcat tcagcttctt caaatggaca
     9841 tcgtgcctcg atttgttgaa tggtcgaaac aaggggaagt tggtcgtaaa aaactgaatc
     9901 aagcgactcg atatctgaca ttagtattgg catttatcca atctgtcggt atcactgctg
     9961 gattcaatca atacgctcaa ttaggtttcg tgaataatcc taacgtagca acttacgtaa
    10021 cgatcggttt gattctaaca gccggtacga tgtttgttac ttggctagga gaacagatca
    10081 cagaaaaagg tatcggaaat ggcgtatcaa tgatcatttt tgcaggtatc atttctagat
    10141 tgcctgaaag tatcagagaa atttatgaag attactttat aaatattgat ccttcagaca
    10201 tatggaaatc tgctattttt gtggccattt tactagtagc ggtcttgttg atcgtgacat
    10261 tcgtaacatt tttccaacaa gctgaacgca agatcccgat ccaatatacg aaacgcgtag
    10321 ctggcgcgcc tacaagcagc tatctgccgt tgaaagtaaa tgcagctgga gttattccag
    10381 ttatctttgc tagttcgttt attgctacgc caaatgctgt tttacaagca ttgagcggta
    10441 gattcggttc tgaaaactgg tacaaagtga tgatggagat ctttaactat aatacagcac
    10501 ctggtgctac gatttatacg attctgatcg ttgccttcac tttcttctac gcctttgttc
    10561 aagtaaaccc tgagaaatta gcggaaaact tgcaaaagca aggaagttat ataccaagcg
    10621 tacgccctgg taaggggact gaagagtatg tctcaagatt actgatgcgt ttaagtacag
    10681 ttggtgcagt cttccttggt ttagtggcat tgcttccaat cattgctcaa atggtttggg
    10741 atcttccaca atcaatcgga ttaggcggta caagcttact gatcgttatc ggtgtagctt
    10801 tagaaactgc gaaacagtta gaaggcttaa tgctgaaacg taaatatgtt ggattcattg
    10861 agtaagaaag cgtgttgagg tttcccctca acacacgttc tcacacattt attaggaggg
    10921 aaaacaatga acctcatttt aatggggctg ccaggcgcag gtaaaggaac acaagctgaa
    10981 aaaatcattg atgcttatgg tattccgcac atctcaacag gagatatgtt ccgcgcagcg
    11041 atgcaaaacg aaacagctct tggcctggaa gcaaagtctt atatggataa aggtgcatta
    11101 gttcctgatg aagtaacaaa tggaatcgtg aaagagcgac tagctgaacc agatacagag
    11161 aaaggcttct tattagatgg ctttccacgt acgctagatc aagcaaaagc tctggacgca
    11221 atgctaaaag atttgaataa aaaaattgat gctgtcatcg atatccatgt tggtgaagaa
    11281 atcttggtcg aacgtctagc cggccgattt atctgcagca attgtggagc aacttaccat
    11341 aaaattttca accctacaaa agttgaagac acatgtgatc gttgcggtgg gcatgaattc
    11401 tatcaaagag aagatgataa acctgagacg gttaaaaatc gtctggctat caacatcaaa
    11461 aatagtgaac caatcttggc ttattataaa gaacaaggtt tgctaaacac tattgatggt
    11521 gctcgtgaaa tcgatgctgt atttgcagat gtacaaaaaa tcattgaaaa atagcacgat
    11581 tgcccgtagc cgacttgcat tatgcagtta ctcttgtcaa gttcaataaa ttatgataga
    11641 atatgtcagt ccgacttcta gagaatcctc tagatgatcc attttgagaa ttttgaggtg
    11701 ggaactgcag tttccgccat tttatcgtgt gaaaatgcga aacaagtaca aggaggtact
    11761 gtgcgtggca aaagaagata tgattgaagt cgaaggtaca gtcgtcgaaa ctttgccgaa
    11821 tgcaatgttt aaagttgaac tagaaaacgg acaccaagtt cttgctactg tttcaggtaa
    11881 aattcgtatg cattacatcc gtatcttacc tggtgacaaa gtaacggttg aattgtctcc
    11941 atacgatctt aaccgtggcc gtattactta tcgctttaaa taattgtact ccgtaaaact
    12001 acaggaggta ttatcatgaa agtaagacca tcagtaaaac caatgtgcga acattgtaaa
    12061 gtaattcgtc gtaaaggacg cgttatggtg atttgcccag caaatccaaa acataaacaa
    12121 cgtcaaggat aattggaggt gctataaata tggctcgtat tgcaggagta gatattcctc
    12181 gtgataaacg tgtagtagtt tcacttactt atatctatgg tattggtaac actactgcta
    12241 aaaagatctt agctgatgct ggtgtatctg aagatgttcg cgttcgtgaa ttaacgaatg
    12301 aacaaacaga tgctatccgt gcagaagtag ataaattaaa agttgaaggg gatcttcgtc
    12361 gtgaagtgaa cttgaacatc aaacgtttga tggaaatcgg ttcttaccgt ggaatccgtc
    12421 atcgccgtgg attgcctgtt cgtggacaaa acacgaaaaa caatgcacgt actcgtaaag
    12481 gcccagctcg cgctatcgct ggcaagaaaa aataattctt aagtgaagga ggttaaaact
    12541 tcatggcagc aaaaaaagtg aatcgtaaac gccgtgtgaa gaagaatata gaagcaggta
    12601 ttgcacatat ccattctaca ttcaataaca ctatcatcat gatcactgat actcacggaa
    12661 atgcattagc gtggtcatca gctggttcat taggtttcaa aggaagcaaa aaatcaactc
    12721 cttttgccgc tcaaatggca gcagaaactg ctacaaaagc agcaatggaa cacggattaa
    12781 agactgttga agtaacagtt aaaggacctg gttctggacg tgaagcagca attcgttcat
    12841 tacaagctac aggtttagaa gtgactgcaa ttcgtgacgt gactccagtt cctcataatg
    12901 gtgcccgccc tccaaaacgc cgtcgtgttt aatgagtgcc gctcattttg agttttatca
    12961 gtaacgtcat tgaacaagac acttttcgtt ttgaaagggg taaagataag aatgattgag
    13021 ttcgaaaaac caagaatcgc aaaaattgat gaagaaaaag attatggcaa gttcatcgtt
    13081 gaacctcttg aaagagggta tgggactact ttagggaatt ccctacgtcg tattttatta
    13141 tcttctttgc caggtgctgc catcactaat attcaaatcg atggtgtact gcatgaattc
    13201 tctaccatca aaggtgttag agaagacgtc actcaaatca tcttgaacat taaaggctta
    13261 gcgctgaaaa tgtatggcca agaagaaaaa acccttgaaa tcgatattac cggacctgct
    13321 acagtaactg ctggcgatat tatcgttgat agtgatgtag aaattcttaa caaagatatg
    13381 tacatctgta gtgtctctga aggagctacg ttccatgctc gcttaacagt gaaacctgga
    13441 cgtggttatg ttcaagcaga tgaaaataaa aaagaagata tgccaattgg cgttcttcca
    13501 gtcgattcaa tctacacacc tgttcgtcgt gtgaactatc aagttgagaa cacacgtgtt
    13561 ggacaccgtg aagattttga taaattgacg atggagattt ggacagatgg ttcaattgaa
    13621 ccgttggaag caatgagttt gtctgcgaaa atcatgactg aacatttgga tatttttgtg
    13681 aacttaactg atgaagcaaa aaatgctgaa atcatggtcg aaaaagaaga aacacaaaaa
    13741 gaaaaaatgt tggaaatgac gatcgaagag ttagacttgt ctgttcgctc ttacaattgt
    13801 ttgaaacgtg caggaatcaa tactgtacaa gaacttacaa ataaatctga gcctgaaatg
    13861 atcaaagtcc gtaacttagg acgtaaatca ttagaagaag ttaaagcaaa attgcacgac
    13921 ttaggtttag gtttacgtaa agaagattaa aaccttttac gaaggaggga aaccaacgtg
    13981 agttatcgta aactaggacg cacatctagc caacgtaaag cgatgttgcg tgatttaaca
    14041 actgatttat taatcaacga acgtattgtg actactgaag ctcgtgcgaa agaagttcgc
    14101 tcaactgcag aaaaaatgat cactttaggt aaacgcggag atttgcatgc acgtcgtcaa
    14161 gctgcggctt tcgtacgtaa tgaagttgcc agcgtgcgtg aagaaaatga ggacatcgtc
    14221 attgaatcag ctttacaaaa actgttcaac gatattgcac ctcgttacgc agaacgtcaa
    14281 ggcggataca cacgcatttt gaagacagaa ccaagacgcg gtgatggtgc accaatggtt
    14341 gtcttagaac ttgtctaaaa tcacactaat aacatcactt tatagatgat tcttttagag
    14401 tgttatgatg ttggaagata tttttccgag tctagctcag cgctgctcct caagcgaata
    14461 tcgcttgggg agtaagcact catcataaag tgttttttta taccttcaat tacctgtcat
    14521 gacagatatg tttgaaggca taaaaaaaca ttttaagcga gaaataattg aaaattttgt
    14581 ctttttttga tagtgttagt aggaacttta ggatgaagaa ggagtaatca tggagccaat
    14641 tattgaatta gaaaagataa attataaata ccagccagat gatcttcgcc ccgcattgaa
    14701 agatgtctcc tttacaattg ataaaggtga gtggatcgct attattggac acaatggttc
    14761 aggaaaatcg acacttgcca aaacgatcaa tggattgctt ctgccagaat cagggatcgt
    14821 gaaagtggga aatcaaatat tggatgaaga aaatatttgg acgatccgac agatggttgg
    14881 aatgattttt caaaatccag acaatcagtt tgttggttcg acagtagaag atgacgttgc
    14941 ttttggtctt gaaaatcaag ggattcccag agaagaaatg ctagtgcgtg tgaaagatgc
    15001 acttgagaaa gttagaatgg ctgagtttgc ttcacgcgag cctgctcgtt tatcaggagg
    15061 gcaaaaacaa cgtgttgcca ttgccggcgt ggttgcctta cgacctgata tcattatttt
    15121 agatgaagca accagtatgc tagatccaga aggtcgtgaa gaagtgatct ctacgatcaa
    15181 gaagatcaaa gaagaaagtc aattgaccgt tatatctatc actcatgata ttgatgaagc
    15241 agctaatgcc aatcggatac tagtgatgag acaaggcgaa cttgtccgtg aaggtacacc
    15301 aaaagaaatt ttttctgctg gtcctgaact gatcgactta ggtctagatc taccatttcc
    15361 tgaaaaactg aagagcgcac tgaaagaacg tggggttgat gtgcccagtg aatatatgac
    15421 agaagaaagg atggtggatt ggttatggac atccgttttg aacaagtaga cttcacttat
    15481 cagccgaata caccatttga acaaagagcc ttatttgaca tcaatatgac gatcaaagaa
    15541 aacagttata ctgcattagt agggcatacc ggaagcggga aatcaacctt acttcagcat
    15601 ttgaatgcgc ttgttaagcc aacaagcggt acagtccata ttggagaacg agatattcag
    15661 ccggatacgg ataataagaa tttaaagccc atccgaaaaa aagttggcat cgtctttcag
    15721 tttccagaag cacagctatt cgaagaaacg gtagcaaaag acattgcttt cggtcctaaa
    15781 aactttggtg tcagcgaaga agaagcacta gtcctagcaa aagaaacatt agaacaagtt
    15841 gggctggatg aaagctattt ggaacgttcg ccatttgaac tttcaggagg gcaaatgcgt
    15901 agagtagcaa tcgctggtgt gcttgccatg aggccggaag tacttgtatt ggatgaacca
    15961 acggcaggac ttgatcccca gggcagaaaa gaaatgatgg agatgttttg gcgtcttcat
    16021 aaggaacagc agatcactat tgtattagtt acgcatttaa tggatgatgt agccaatttt
    16081 gcagattatg tctatgtgtt ggaaaaggga cgaatcgtta atagcgggga gccgcaagag
    16141 gtctttcaaa acattgaatg gctaaaagaa aaacaactag gcgtacctac tgccaccgag
    16201 tttgcagaag aattaatggc taaagggatg aactttgcta ccttgccttt gacagctgaa
    16261 gaattagcag acgctatcgt ccattatgct ggaggaaatg cccatgatga ataaattgat
    16321 atttggtcgt tatatgcctg gagattcctt gatccatcga ttggatcccc gagctaaatt
    16381 attagccagt ttttatttta tcggaatcat ttttttagca aataattggg aaacgtacct
    16441 tttgttggca tttttcacat tactttctgt cttcttgtca aaagtagatt tgaaattttt
    16501 tatccgaggc attcgcccat tgatctggct aatcctcttc actgtagctt tgcaggtctt
    16561 gtttacaagt ggcggagaaa cttattggag ttggggtgtt ttccatatca ctgaatttgg
    16621 tgtgatgaac ggcctcttta ttttctgtcg attcgtgttg atcattttta tgtcgactct
    16681 actcacgctt actacaccgc ctttggaatt atcggatgcg attgagtact tgcttcgtcc
    16741 attgaaagcc gtacggttcc cagtccacga aatttcattg atgctgtcga ttgctcttcg
    16801 ttttgtgcct acattgatgg acgaaacaga aaagatcatg aacgctcagc gcgctcgcgg
    16861 tgttgatttt ggtgaaggaa acctagttca gaaaatgaaa gcagtcattc ctttgctgat
    16921 tcctttattt gtcagcagct tcaaccgtgc ggaagatctt gcgactgcta tggaagcaag
    16981 aggctacaaa ggtggggaag gaagaacgaa atatcgtgta ttgcattggc ataatagaga
    17041 cacgatggtt atcattgctt ttgtattatt aactgtgcta ctgatctttt taagaggata
    17101 aacgttcagt gggccgctat ctattctttt cttgctgatc tgtttgcaag aaaggatgca
    17161 agcagtgtat gacaagaaat attagggtct gtggcagact aaggtcacag gcctctttct
    17221 tttatctgaa aagaaagaac gaaaaaattt tatagaaaaa tcattattcc agataacctt
    17281 ttaggaacaa aggagagaaa aacatggtac gttacaaagc aatcattgcg tacgacggaa
    17341 caaattttaa tggattccaa aaacagccaa atgggcgtac tgttcaagaa gaagtagaaa
    17401 aaacattaca aaaaatggca aatggaaaag aaatcacggt ctttggttcg ggaaggacag
    17461 atgccggagt acatgcgatc gggcaagtaa tccattttga ttatccagag gagcgtccgt
    17521 tagaacgaat gcgtttcgcg ctagataccc agtcaccaga ggatattgct gtaagacaag
    17581 tagaaattgt ttcagaagac ttccacgcaa gatatttggt caaagaaaag acgtatcaat
    17641 ttcgagtgga tatagggaaa ccacgcagtc cttttcgacg ccattatgca agttattttc
    17701 cttacccact tgatttggaa aaaattcagc gggcgcttcc tgatttatta gggactcacg
    17761 atttcacctc tttttgtgca tcaggaagct cgatagagga taaaatacgt acgatctacg
    17821 aggctaagat ggaggtaaat gaaacaaaag acgaattgtt gtttacattt aggggaaatg
    17881 gcttcttgta taagatgata cggatcttag taggaacgct tttgaaaatt ggcaatggcc
    17941 gattgcctga agatagtatc ccagatatta ttgcgaaaaa agatcgtaat gcagcaggac
    18001 ctacagcaca ccctgaagga ctttatttgt atgaagtgaa atatgaataa gaggttatga
    18061 tagaagtggt cagcttcaag aaataagaag gtatttacga aaattacttc tcaaaatttt
    18121 gcaaaatttc ggcttatttt cgaagaagct acttctggaa caccgtttaa gaaagaggtc
    18181 gtgagcctgt catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct
    18241 ttgatgaata tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct
    18301 attttttctg taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt
    18361 ctgaacaggt tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt
    18421 gttcttctat tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga
    18481 cataaagaat aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt
    18541 caggcaagta actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg
    18601 cgtctttgaa attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt
    18661 cataaggaat agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt
    18721 ttctgccagt ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat
    18781 aggctacaac atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat
    18841 aaaaacttgc agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt
    18901 gaccagaaat gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag
    18961 aactttctaa ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag
    19021 gcacatggac ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga
    19081 cgccagtcgt tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga
    19141 atgtaaaata ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca
    19201 aattatctgt cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg
    19261 gcaatgcatt gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc
    19321 catatttact gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat
    19381 ccatcagcaa agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac
    19441 ctaatttatc caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac
    19501 cactgtaacc atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt
    19561 aaaacgagtc ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat
    19621 cagtatataa actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt
    19681 tcgtattgac cagtgcttca gcagacatga tcaataataa caatatactc agatgattga
    19741 atgaaagttt tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca
    19801 ctgtcaatac aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc
    19861 atgccaccgc aaagagagca gctacgacca aaatgattcc taacaacagc ccaccatcgt
    19921 cttgttctat cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat
    19981 aggcataacg gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg
    20041 gaacaagata aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt
    20101 tcaacggtac tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg
    20161 cgtaaacgaa cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca
    20221 tgattagatc cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct
    20281 cgccatttga ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg
    20341 ccagtaaaga agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca
    20401 atagacgggc gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac
    20461 tggataaaaa caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa
    20521 cacgatgaat ccccaaaatc actaatggaa gataaacaaa tgcatccagc cacatgatga
    20581 tctccgaatg tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc
    20641 cccagcgagg aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga
    20701 ccttaagcaa agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca
    20761 ccagtggcgt gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta
    20821 gagaagcatt ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg
    20881 catgaaaatt agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag
    20941 gatagattcc gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag
    21001 ctgctgcgta gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt
    21061 tccaccaaat ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa
    21121 aaagagtcta gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg
    21181 tataacaaaa ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt
    21241 tattaaataa aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt
    21301 caacttttcc tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga
    21361 ccataacgcg aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt
    21421 gtgaacggtt gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg
    21481 taatttcctc ctttgccttg atttggagca atagaataat tcagctcata ccagactaac
    21541 atatcatata gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa
    21601 gaataattgt aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg
    21661 ggtaactgcc ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag
    21721 ttttttaccc gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc
    21781 attgaaatta ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc
    21841 ggtgttgtag gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt
    21901 aaagaaaatt actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat
    21961 gtttatacga ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa
    22021 aaagtgaaat acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt
    22081 gtacaaggtg ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg
    22141 atctgaagga ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa
    22201 atggtccagg caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat
    22261 gtattccctg tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga
    22321 gctaaggcag tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca
    22381 aaaggattgc tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt
    22441 ggattttcta agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc
    22501 ttcactcatg gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt
    22561 ttgacagtag ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat
    22621 gtcgttgaag taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca
    22681 gacttgcttc cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg
    22741 tttgtttatg agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat
    22801 gaaccttctc cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa
    22861 ggtcaaatgg cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc
    22921 ggagaaggac ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat
    22981 ggtataggag attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat
    23041 acagaaaacc caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc
    23101 aaagtcgaca acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac
    23161 gagtttgcga aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt
    23221 aaaggcgtcc aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa
    23281 acaatgaatc caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa
    23341 gtgattgtct tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta
    23401 gcagatatcc cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg
    23461 ctttcattca atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg
    23521 tctagcgttg tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta
    23581 gagatcaaag aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca
    23641 gatatcacag caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc
    23701 gtaacgatct tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa
    23761 ctaacagaaa aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat
    23821 ccttatctat tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca
    23881 ttcataaaag gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt
    23941 aaaggaggga ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag
    24001 tcggagaaaa aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac
    24061 tgacttatta tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg
    24121 atcaagaaaa ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg
    24181 gttataaaaa aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt
    24241 ctttttttaa tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat
    24301 acggtaaatg ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa
    24361 caatggatga cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag
    24421 ttgatctaat caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa
    24481 acaaccttgt ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt
    24541 ttccaaaaga ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct
    24601 ttttatttca aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt
    24661 tggagatcct ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac
    24721 tgacaaatgc acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc
    24781 atatgcagcg acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg
    24841 cgttatacgc taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct
    24901 tggcacaaca acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg
    24961 cattgattac ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc
    25021 aaggggaaat taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc
    25081 agaatttagg tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag
    25141 tacttcgtga aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta
    25201 gaacattagc tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag
    25261 ctggacgtat cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg
    25321 attggacgaa aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg
    25381 aagaatcaga agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac
    25441 tatttgcacc aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag
    25501 aagtaatcat ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa
    25561 ttgaagtagg ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat
    25621 ttggattggc acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct
    25681 actgtatctt agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga
    25741 cagagaccac caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg
    25801 aagtatttgg cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg
    25861 atggaaatgt tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt
    25921 ggcagatgct tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata
    25981 atcgttattt cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg
    26041 aaacaatgaa aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag
    26101 aaggcgtggc tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag
    26161 aagcagaaat caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg
    26221 aaaaaatcaa tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa
    26281 tggtccttgc tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga
    26341 atacaggcgc gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac
    26401 gccctggctt gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc
    26461 tggatcttgg cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag
    26521 gttcttttta tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca
    26581 acggaacaga agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga
    26641 atgaaacaag cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg
    26701 ctgatgtagt ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa
    26761 cagcaatgaa tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa
    26821 aaatgggcgc tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt
    26881 ccaaacatgg cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag
    26941 caacaggccc cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag
    27001 atgtagttgg acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct
    27061 gaagcgatcc gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag
    27121 ccatggtgta ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa
    27181 gaagtattta acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa
    27241 gtgacggatg aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa
    27301 ttcgttttag agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa
    27361 attgaaacag tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata
    27421 aaagcaaaga aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt
    27481 gacacgtaaa agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt
    27541 aaagcggttt tctatataat tattaataat tcattacaca aagataagaa taacctttgt
    27601 tataaaacga tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa
    27661 gcagagaggg gtattcgatt gtccgataac caattattag aagttcagaa cctacataca
    27721 ggattccgac tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac
    27781 aaaaacgaga ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact
    27841 acgattatgg gattacttga tcctaataac acaaaaatta caggtgagat tttatataac
    27901 gatctgaatt taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc
    27961 ggaatgattt tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag
    28021 atcaaagaag gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca
    28081 ctagaattgc tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc
    28141 catgaactat caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa
    28201 cctccaatcg tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag
    28261 attcttgatt tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact
    28321 catgacttag gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag
    28381 ttcgttgaag tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc
    28441 tctttactga actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa
    28501 ggtgtcgttc cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt
    28561 ccatggatac cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac
    28621 cacttggtac gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg
    28681 tagatgacag aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga
    28741 ttcttcaatc gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa
    28801 aaaggaaaga catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa
    28861 gccgttgtgg gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta
    28921 acgaagcgaa gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa
    28981 gattcaatgt ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc
    29041 cgaaattttg aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat
    29101 atcgttggga tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa
    29161 cgtcaacgtc taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat
    29221 gaacctgtat ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga
    29281 atccagcaag aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa
    29341 cacatgtgcg acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga
    29401 gaagacattt ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg
    29461 caaatcgatg tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag
    29521 tatatccaaa accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg
    29581 atcacaacta cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga
    29641 ttctgcgacg tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct
    29701 tattagccca agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc
    29761 cggcagtgat cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt
    29821 acttccgttg gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac
    29881 gctctgttgc tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga
    29941 cagttgtcct tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa
    30001 attcaatctt ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat
    30061 ttatcttcgg cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa
    30121 gtggatcaca aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga
    30181 aatatattct gttaccatca attacccaag catttttggc gactgccgtc acaatccaat
    30241 atctgcgaag tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca
    30301 aaggggtacc gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga
    30361 tggcttctca aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa
    30421 agatttttgg ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact
    30481 ataccgtgat cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac
    30541 tttcagatat catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag
    30601 aaaggagaat ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc
    30661 tatggggata cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt
    30721 aggtttgcta gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga
    30781 caaagtgatg tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca
    30841 aggacaaaag ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat
    30901 cataggtgct agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat
    30961 cggggttgga ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat
    31021 gcggatcgtt gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc
    31081 gattatttcc agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt
    31141 agctaaagcc cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag
    31201 tgcctcaaaa acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa
    31261 tctaagttca ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga
    31321 gacaactttg actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt
    31381 gatcggttat gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc
    31441 atcaatcctt attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg
    31501 ttctgcagat gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga
    31561 agaaaacgat ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg
    31621 gcggaggtac agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat
    31681 taacttttcc aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag
    31741 ctgcggtcgc aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt
    31801 catatgatgc agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt
    31861 tcagaatcac agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga
    31921 caatcaaagt aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg
    31981 tgattttccc ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca
    32041 ctttccgtaa catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg
    32101 gaatcaaaaa aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca
    32161 tgcttcaatc gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg
    32221 tagcaatcaa agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc
    32281 cttattacat gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact
    32341 actggaatgg tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg
    32401 caactgaagc attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt
    32461 acgataccta taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata
    32521 cttatctagg attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc
    32581 cagattcaaa aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata
    32641 atgcagtagg tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc
    32701 cagtattcca gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag
    32761 cgaaaaaact attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag
    32821 acaaagatgg aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc
    32881 aaccattggc agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca
    32941 caacaggtcg tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg
    33001 aaattgatgt ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat
    33061 ggggaccaaa tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga
    33121 tcaacgatat cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa
    33181 aatggcaaca atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag
    33241 tattgccagt caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat
    33301 gggcaaatgt ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag
    33361 ggcgatgtcc tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca
    33421 aggcgctgat ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta
    33481 agtcaaattt atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga
    33541 aactaaacga atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac
    33601 cttttgaccg aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa
    33661 aatatccata aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa
    33721 ctataacatc gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta
    33781 tgtgaatgag catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga
    33841 tgccgtttta gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga
    33901 aggaaaattg acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc
    33961 caaagaatgt cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg
    34021 acgtacgcga ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct
    34081 tgaccaggga ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa
    34141 agcaggtgct ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa
    34201 atcaggtgat gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg
    34261 agtattttgg atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc
    34321 gaaaaaatta gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt
    34381 gagggaaagc tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca
    34441 agacagtcat tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa
    34501 aaagcaatat tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc
    34561 gaggcggaaa aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata
    34621 ttgcagaagt cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg
    34681 agatcagtgt aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac
    34741 aaagctgcag attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat
    34801 cgttctcaat catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc
    34861 gtcgtgggat ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag
    34921 cagaacagaa gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg
    34981 aattggaaga acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac
    35041 ggctaaaaga aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag
    35101 caaaaaaaga ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca
    35161 aactatctga gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg
    35221 cgcaagccga tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac
    35281 tgaagcagac agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa
    35341 gctcgcaaga atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa
    35401 agcttcaaga aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg
    35461 aagcaaatct cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat
    35521 tattggcaga attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa
    35581 acgaactgaa gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt
    35641 tagccaagca atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat
    35701 tgacacaaaa gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa
    35761 tgatccaaca aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt
    35821 atcaattaat gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc
    35881 aagaaaacta ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc
    35941 tttcgggtat tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag
    36001 ctatcgaaac agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg
    36061 ctcggcaagc catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac
    36121 tgacgacaat caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag
    36181 aagggtttat agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg
    36241 ttcaaaacct gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg
    36301 cgcaaacgat ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg
    36361 gaggatccat gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa
    36421 atcaagaatt gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac
    36481 aagaaaaaaa agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag
    36541 ttttgcgtac acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac
    36601 aaaacatcat aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga
    36661 cacgtgaact gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca
    36721 aacaaacaga tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc
    36781 aagaaagcga ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac
    36841 aagcagatct tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg
    36901 cccgagtcca aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga
    36961 cattgacagc agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta
    37021 acgaattatc tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc
    37081 gagatagaag gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg
    37141 agcaaaaagc acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa
    37201 tgattttaga taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag
    37261 cttcccaaga ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct
    37321 taaaagaaca gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac
    37381 aagtcagtga aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa
    37441 accaattgtt tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag
    37501 tatttgaagc tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta
    37561 aagctgaatt agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag
    37621 tacaacctcc tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac
    37681 ttacagccat cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct
    37741 tagatgaggt agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga
    37801 gcgatttcca agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg
    37861 cagcagatgt actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg
    37921 tacggatgga agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa
    37981 aatgatcaaa ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat
    38041 ttcagatgag aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct
    38101 atgtacagga cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga
    38161 tgaaggtgac tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga
    38221 aatcatggaa aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca
    38281 gcaattggat ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc
    38341 cccaaggaag caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga
    38401 tataagcgat attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga
    38461 agaattagat cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat
    38521 caaaacaaga agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat
    38581 ttctttattg gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga
    38641 ggaaaatgat ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt
    38701 gcctttcgtc aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc
    38761 caaagtgatc caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa
    38821 tcaagcgtgc ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg
    38881 acaagggttt agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca
    38941 attttcgaac agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag
    39001 atgtaggttt tgaaacagcg atacgaatta ccgaagcatt acgtcaagaa gtgaaactca
    39061 gaaatgcgaa aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct
    39121 atgaagcgga aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag
    39181 ttattttgtt tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc
    39241 atcagttcaa aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg
    39301 gagcaatcga ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca
    39361 atgcaggagg cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc
    39421 aggcagatgt tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga
    39481 acgaattaga aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa
    39541 cacttcttgt attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca
    39601 aagaaacaac agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg
    39661 gtatcgtact tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg
    39721 aaggaatcga tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag
    39781 gattactaaa agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc
    39841 tccttgtttg aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact
    39901 tatttgtaag cggttctcaa acaatttcgt tctttttctt agactttttg attataatta
    39961 gattcatatg aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca
    40021 atgcgcgccc ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg
    40081 atcttgcagg aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc
    40141 acccctatat ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg
    40201 attctattcc cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta
    40261 taccgaaaga agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg
    40321 aagagatcat tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag
    40381 caaaagaata cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg
    40441 gcgatgagtt gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat
    40501 tcaaaacaga actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca
    40561 cttatttatt cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc
    40621 cgcaagaacc tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg
    40681 tgaaagtttc ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag
    40741 aagggaaact ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga
    40801 aagtcgcaga tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga
    40861 atccttatgc aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga
    40921 tgtacatgtt atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga
    40981 ctcgaaataa caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag
    41041 gtagagaaat tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc
    41101 tttatttagt agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga
    41161 aactctatca agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc
    41221 aatattataa agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac
    41281 tttctactca gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag
    41341 atgagtcgga tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg
    41401 caaacatgac aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa
    41461 cgaaaaaagt cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca
    41521 tggaagaagc ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta
    41581 aatcaaccaa ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt
    41641 atcaagcagg tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta
    41701 tgccgggaac ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc
    41761 gagtccctgc taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa
    41821 aaaatagtga ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag
    41881 gtgaattaga acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag
    41941 ccaatcaaat tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg
    42001 atatgactga tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac
    42061 taggagctaa gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa
    42121 ctgataaaaa agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg
    42181 tttatccttt tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc
    42241 ctgaagtatt ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc
    42301 aaaagctttt tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca
    42361 gaagcttttt ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta
    42421 ttttttttcg atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc
    42481 gaattcctca ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt
    42541 cgttgctagc tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat
    42601 ggaagcatct ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat
    42661 catttcagca acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg
    42721 ctgttcttca gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac
    42781 atcatcttgt gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc
    42841 atattcccaa taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact
    42901 taaaataaga atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac
    42961 tagtagcatt attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac
    43021 aattgtcaga actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt
    43081 tgccacgaac gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca
    43141 tgcaacattt gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg
    43201 cgcgtttagg tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat
    43261 ccttgacagc attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat
    43321 tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca
    43381 ttggttcagt tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat
    43441 ggcttcaagg gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg
    43501 ttccattgtt gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg
    43561 aatcgtttgc agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct
    43621 tagtatcatt ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag
    43681 tgatcattcc gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg
    43741 taactgcttt agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga
    43801 tttttcctta tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc
    43861 tttatcttct gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt
    43921 atgcttgttc ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac
    43981 tggcattttg catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta
    44041 gctgtcagca gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct
    44101 tcagtattgg gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc
    44161 ggaggagtga cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg
    44221 atggtcgggc tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt
    44281 tttttattac tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt
    44341 ttacaagtca tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc
    44401 tttggcaata tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg
    44461 tacctgttat ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca
    44521 gtaaacctcg ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt
    44581 ttgacaggga catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca
    44641 aatatcagtt atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt
    44701 ctggtagcta tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg
    44761 aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg
    44821 attcgcgaaa ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg
    44881 gaaaatcagt ggttaaagat gtacagttaa cgattcctga aaagaaattg actgctttta
    44941 tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa
    45001 aagatacagg tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat
    45061 tagccaaaaa attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga
    45121 aagaattagt agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg
    45181 aggaaatcgt tcaggaatca ctggaacacc ttgggttaga agaaatagcg gatcaatcga
    45241 ttgacactct ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag
    45301 acacggatta tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc
    45361 aaatcatgca gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc
    45421 ttcatgatat caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac
    45481 agttatttac gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat
    45541 acgaaatgga catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa
    45601 actaacatta ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca
    45661 tttggtttag cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc
    45721 agcacacaaa ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg
    45781 ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct
    45841 cttggtgttg gagataaggt agttggagca gctacaagca gccttcctga gtatctttca
    45901 tcctataaaa aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat
    45961 cagcttcagc cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta
    46021 agtcaaattg ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc
    46081 cagcaaaatg tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa
    46141 ttagaggaat tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa
    46201 aaagcactag tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga
    46261 ttcggtttca tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc
    46321 actcacggtc aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt
    46381 gtagtagaca gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat
    46441 gaactggtag cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat
    46501 gtctggtatt taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat
    46561 caagcattta aatagcataa ataacagagg attaaactct catactatgt aacaataatg
    46621 tttcttacat tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt
    46681 aaaatcgtat tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg
    46741 tgaattcatt atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg
    46801 tgatccattt tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga
    46861 aacttagata aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga
    46921 tgttccatct gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt
    46981 ttctgtccag cgttcttatt actcaaagca aatcgcagtt gtcacaatct cttctaaacg
    47041 atgttccatc tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat
    47101 tttctgtcca gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac
    47161 aatgttcaat cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt
    47221 aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg
    47281 cgggaagctt actccaccgt tttaataatt gatagaaata actctcttct gctttgattt
    47341 tatactcgct taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa
    47401 tatccaatgc tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac
    47461 cctcgatatt ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga
    47521 ttcctccaaa gaagtctttt atttgataag tttactctac cgaagagttg ttaataatcc
    47581 gtgaacaaaa agtaattctt tttccaatag ttgttaaagg ttttttattt tttatagtat
    47641 tttttgttat ttaagaaagg aataaggtta aacaaataac aggttgcttt ttgggtcttt
    47701 ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc tcttttgtga taagagaaat
    47761 cataataaac gaatgactta ctttccaata aattgagaac agtcagaacc agacaaatta
    47821 gttgcatctg atgaataaag tgattattct atgacatgag gtgatacaga tgaaattaga
    47881 agtgacaaaa gaagcacaag aagtattgaa gaataaatta gaagcagacg atcaactttt
    47941 attagatatc gaaaacggtg acggtccatt tgcagaaagc caagtcagtt gccaattgga
    48001 tacggcattt cgattgatca ttgtcaaaaa agatacacaa acagatctaa gtctttattc
    48061 tgtagtggct gatacaccag ttggaccaat caaaatcaaa gacagtgcaa tactttacat
    48121 ggatgatcca tccacacttg ctttagaacc aacttataat agtttacaat taaaaggacc
    48181 aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa gactagaggg ataaaatggg
    48241 aaaattggcg atcatcagcg acctacatgt ggacatcaat aaattcggcg aatcagagct
    48301 gatgcagctt tggcaagttt tgcaaaagca caagatcact cggcttcatc tagccggaga
    48361 tacggctaat aaagtagacc gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt
    48421 atctacgaca tttcatttcg gcaatcacga gttggcagat gtgcccaatg aacagatgat
    48481 ggaccatttt ccagacccac attttttaaa tgaacggtat attgctttaa atgagcagac
    48541 cgttctttta gggatgaatg gctggtacga ctatcagttt tccgaattga aagattacga
    48601 ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac
    48661 agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa aatttgctag accagctgga
    48721 agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt cctaaacggg catttatcat
    48781 gtatcaatct gctccttatg agcgttggaa caaattaaat gcatttttag gatcagaatc
    48841 attcggagaa ttacttgacc gttattcaaa tatcaaacaa gtagtttttg gccatacgca
    48901 tcgtcgcttt gaagataaat ccatcggtca cacgatttac agctgcagac cttttggtta
    48961 ttattatgaa tggcagctga cccgagattt tgtcttgaaa gaacagttgc tagacagcta
    49021 tgatcctatg aaattacgtg tcctcttgcg tgcccatcac ccagcttttc aggcctatca
    49081 aacacaacat ttgcaagagg aatttgaaca agcgatgaca atcgttccgt attgagacag
    49141 cattagtaat gtgtaaaaga aaataccttg taaaacataa ggataagtaa gagcagtaga
    49201 tccatttatc gtggatatgc tgcttttttt gcggaaaata atcagcgaat gtttatttga
    49261 tcggatgatt tgtaactcgc agagtactag atgcaagcgt gtattctttt tttgaacgat
    49321 aatcacaaaa aaaaatataa tatacatttt ttatttaatt ataattaata ttgattgaag
    49381 tctaggcagt caagtcacat tttgatagat aggaggggga cttacgaatt attttaaagg
    49441 ctatgacagc tgtatttcta gattgtgttt gcatcaagtt gcaataaaaa ctagaaatca
    49501 aatcgggctg ataatcattt ataactaatc gatacatagg accaaatata ggtctatgtt
    49561 cttttatttc ataagtatcg taaaacagaa ttttgctatg gattaatcca atcgactgat
    49621 atgtttagta aataaagaaa gaggaatgtc aatgatgaaa aaagaaatcg tattaacagc
    49681 agcaatgatg ttattcagca tggtagcaag tacgactttt gtttctgcaa ctgaagtata
    49741 cccaaaggaa tataacacag aaggaacgat tacatttgaa gcaggagatg agggtgtaac
    49801 tcctcctgtt gatccagaga atcctgatcc caataaacct gtcgatccat cagatcctcc
    49861 aagccctgga acaggagggg cattatcgat tgattatgga tcaaaattca aatttgggac
    49921 tcaaaaaatt tctactgcgg ataaaacgta ttatgcagct gctgatgtga tgaacgatgg
    49981 gtctagaaaa ccgacatatg tccaagtgac agataggaga agtaccttat ctgggtggaa
    50041 attaagtgtc tctcaaccag aacagtttaa aactgccagt ggggatgaac tagttggagc
    50101 acagctgaaa tttacgaaag ggcaggctgt ttctttggtt gatccaacat atacgccgca
    50161 aacggtgaat tctgaattaa cgttgacacc gggaggaaac aatacgttag caattaatgc
    50221 taaatcagga acaggtgtgg ggacttgggt ctatcgattt ggtgcaaatg aaaatgaaaa
    50281 tcaagatgcg gtacagcttt cggtacccgg taaatctgtc aagttagcgc aacaatattc
    50341 cactaaatta gtttggacat tagaagatac acctaacaac tagtttactg aaaagaactg
    50401 ttaaaaataa atacgtagtc atattgtctt gcgaggtaat cgagcaaaaa ttgtcaaagg
    50461 ctaggctaaa tttgtttgga tacgaatagt tcatctagga atttaacgat caggaggaaa
    50521 agatatattg aaaaagagga ggatcgtgct cattttaagc agtctcttag tgactaatat
    50581 ctttccgatc atagggtact ctttggaatt gaatcagttg gagcatggaa atagaagaga
    50641 cgaagaaagc aaactcactt cgacattcga cagtttaata gaatccaacc agacacaaga
    50701 aagcagtgag gatttaagta tttcgagtag tggagagacc actgacaacg tagaagctga
    50761 gggttcggac aaacaaggac tagaagatgc accaatttct gcggttgagc tgcctgacga
    50821 tcccaatatt atttctatcg ataaaatttt tcaaacacct atcggtacta gcacgtccat
    50881 attggaaaat gggaagttac tgcagttgaa cccagcagaa aggtctcaaa gaggagctat
    50941 ttggtcaaat aagaagatta gtttactctc ggattttaca tttaaatctt atttatactt
    51001 aggaaatcaa cgagatagag cgggagatgg catgaccttt acattgactg gcgatcctag
    51061 aatggctagt aatcccagtc aagttattgg atcgccaggt atgggaattg gctcatattc
    51121 tactcgttct ggccaacctt acattgcgaa tgcgctctcg attgagtttg atacgtataa
    51181 aaatagtggt tcttctgatc gaatggatcg agagataact gctgataata gagggcatgg
    51241 acatgtcgct tttgtcacgc ctaaaccaaa taataataat tattctggag agcatactgg
    51301 cgtgacggta gctcctacat ttctttctaa tggcacatgg cgcttgttaa taattaaatg
    51361 ggacgcggag caaagaagtc ttacttatga tttggaaggt gtcggtcact cttctcggat
    51421 tatacctgat ctcattaggc agtttggttc tacagaagta aattgggggt ttacttcttc
    51481 aacaggtact ttttttcaag aaaatgctgt cgctgtcacg cgacttccat cgaatgtcac
    51541 atcaacagct gatgtaaaag tcaacgatag tgattatggg gccatcgctg aagctggagg
    51601 aaacgataag ataactatca gaaatacatt gaaggtcgag ggggattttc ttgaatataa
    51661 gaaaatgcag actagtatcg acctcccaca agaattaact attcccgagc atatcttgat
    51721 caatggaaat caaattgatg ccaaagatat cttgataacc ggaaatcgag tcacgctaaa
    51781 tctgacagat tattttattg ctggagatac gttaataatc gaattggaga caactttgca
    51841 ggaagtaatt cctgaaaaag tactcactat gcattttgaa taccttgaaa acgggaattt
    51901 gattgagcaa tcgaatgaaa taaacctaaa gatcgcaaag ctgaaggaga tagatatcca
    51961 tgtttattat aaagataaag acagtcagat tgatattgct gaaatgaaaa caatcactgg
    52021 gaaaatagga gagaagtata aagaaactcc tattgatatt gaagggtatg tttttgactc
    52081 ggattcagcg aatacagaag gcatcttctc cgaaaataca gaggatatct atttttatta
    52141 cagaaaaggc aaactttatc tctcaactgc tcctcaatat gtcaattttg gaaaacataa
    52201 aatatccagt agaccattaa gtgaattcgg acagttttca ggtgggttga aaattataga
    52261 tgaacgggct tttggaagtt ggaaattaca attgaaacaa gagaaagttc ttacaaatgg
    52321 agattttgag cttccagaag ctctttcctt tgttacctct gaaaatacaa cggttatagg
    52381 gacatccgct gttacgattt tcgaaagtga tcaaaagggt gaaagcgatt tgtcctctct
    52441 tttagattct acagctcatc gtggaatcag aatagatatt cctgtagaaa accaaagaat
    52501 cggaaccttt gaggggaaac tatcttggat acttgcagat gtcccaggaa attaacagga
    52561 agagaagaat ataacaaaat tattgagttt caagaagggc acaggtacca taggctcttg
    52621 tgtcccacag agacaagatt ttgttatagt cttctcttac atatgattaa aggagcgatt
    52681 ttcttgagac caaaacaaca attatttata acactcctag ttattttagg ggcacttttt
    52741 aacaatatat cagtgtcagc tagtgcattt aatttttcag tgacgccgat aacttcagag
    52801 aatcaaatcg acaagagaaa aacttacttc gatcttcaac ttgatccgga tcaggaagta
    52861 gaagtaaaag cggaattgag aaatgataca gaaaaagaag tgaaaatcga tatttctgtg
    52921 aatagcgcaa ccaccaattc aaatgtgatg gttgaatacg gaaaaaacga gattgaaaaa
    52981 gacatgagcc tgatctttga tctggtagat tatgtgagct atccacagat agtgacgcta
    53041 aaacctaaaa gtgtccaaac cgttgctttt catgtcagga tgccgaatga gcgatttgat
    53101 ggtgtattgg ctggtgggat cacattccaa gaaatccaga cggaaaagga ccaaacagaa
    53161 actaaggatc aaagcttatc gattgagaat gaatacacct atattattgc tttgttgatg
    53221 caacagacac tgaacgaagt tgctccgaac cttactcttc atgaagttaa accagatcaa
    53281 atcaatgcaa gaaatgtcat cttagcaaac gttcaaaatg atcaaaaaac ctatatcaat
    53341 caagtagtta ttgaaacaaa aattacaaaa aaaggacatt ctgaagtttt atatcaagag
    53401 gaaaaagaag gattgcagat tgcgccgaat acaaattttt cttttccaac tgctttaaat
    53461 ggtcaaccgc taaccccagg tgaatatcac cttacaatga ctgttttagg aaatgaaaat
    53521 gaaaatggaa aattttcgag aaaaaaagga aatactacga tcaactatac caatcaatgg
    53581 gtatttgaaa aagattttac aatagacgga aaagtagcca aggaattgaa cacgacggat
    53641 gttacgatta aaaaagacaa taattggatt tatatcttag tagcttcact tttcttattg
    53701 tttattttat tatgcatact tttgtttgtt ttgagaaaaa aagaagagaa agaaaagtaa
    53761 ggttaagata acaaatagta aatttttatt attgtaggat ggttgggctc tttttataac
    53821 aatataaaat ataccatttt attaataaaa atgcatacta gtaaatgata taattctaat
    53881 aacaggtttg atcgcgagaa aggccaaata aaacgctctc caaaatgtta aaaaaaagac
    53941 aggacgatgt atattataca aacaagaatc gctgacaaca gtgactcgga tccaggaaat
    54001 cagttttatc cccagctagt tggtgaatgc atggaaagta atatacgtag aaagagctga
    54061 tgactaatga attatgagtt ttttttaagc aaagaagatc acagaagtta ttcattactt
    54121 aaatatttag aagcaagctc aaatttatca gagtcaatat cgaatgttca agaagagttg
    54181 tcgctatcga catttctctt gaaaaaaacg atcgataagc tgaaacatga tttacaaaag
    54241 ttcgatctag agaaaaattt gcgagtaacc gtcagtgaat tggatatatg tctggaaatt
    54301 aatggaaaat gttctagcaa agctctgtta tctcgttata taacggattc tttatctatg
    54361 aaaatggtat tggctttctt tcaggaaaaa tatatctcag tagaaaattt tgctaaacag
    54421 catcacgtga gttattctgt ggcttataaa gtattacaaa gactaaaaag aaatctaaaa
    54481 aaatatcaaa ttttttttga aaagagaaag ttg
//
LOCUS       DAIGQM010000015        47423 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.015, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000015 DAIGQM010000000
VERSION     DAIGQM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.015"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(144..1622)
                     /locus_tag="NOA48_000832"
     CDS             complement(144..1622)
                     /locus_tag="NOA48_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789117.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOA48_000833"
     CDS             complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOA48_000833"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCI0789118.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2928..3848)
                     /locus_tag="NOA48_000834"
     CDS             complement(2928..3848)
                     /locus_tag="NOA48_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0789119.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3961..4713
                     /gene="xth"
                     /locus_tag="NOA48_000835"
     CDS             3961..4713
                     /gene="xth"
                     /locus_tag="NOA48_000835"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCI0789120.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5577..6110
                     /locus_tag="NOA48_000836"
     CDS             5577..6110
                     /locus_tag="NOA48_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCI0789121.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6600..7124)
                     /locus_tag="NOA48_000837"
     CDS             complement(6600..7124)
                     /locus_tag="NOA48_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789122.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOA48_000838"
     CDS             complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOA48_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCI0789123.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOA48_000839"
     CDS             complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOA48_000839"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCI0789124.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8846..9526)
                     /locus_tag="NOA48_000840"
     CDS             complement(8846..9526)
                     /locus_tag="NOA48_000840"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0789125.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9652..10521
                     /locus_tag="NOA48_000841"
     CDS             9652..10521
                     /locus_tag="NOA48_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0789126.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10547..11062
                     /locus_tag="NOA48_000842"
     CDS             10547..11062
                     /locus_tag="NOA48_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789127.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11109..11702)
                     /locus_tag="NOA48_000843"
     CDS             complement(11109..11702)
                     /locus_tag="NOA48_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789128.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11727..11906)
                     /locus_tag="NOA48_000844"
     CDS             complement(11727..11906)
                     /locus_tag="NOA48_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789129.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11983..12492)
                     /locus_tag="NOA48_000845"
     CDS             complement(11983..12492)
                     /locus_tag="NOA48_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789130.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12588..12968)
                     /locus_tag="NOA48_000846"
     CDS             complement(12588..12968)
                     /locus_tag="NOA48_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0789131.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13298..14047
                     /locus_tag="NOA48_000847"
     CDS             13298..14047
                     /locus_tag="NOA48_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCI0789132.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14231..15508)
                     /locus_tag="NOA48_000848"
     CDS             complement(14231..15508)
                     /locus_tag="NOA48_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789133.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOA48_000849"
     CDS             complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOA48_000849"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI0789134.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16430..17374)
                     /locus_tag="NOA48_000850"
     CDS             complement(16430..17374)
                     /locus_tag="NOA48_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI0789135.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17376..18062)
                     /locus_tag="NOA48_000851"
     CDS             complement(17376..18062)
                     /locus_tag="NOA48_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI0789136.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18536..18856
                     /locus_tag="NOA48_000852"
     CDS             18536..18856
                     /locus_tag="NOA48_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI0789137.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            19010..19915
                     /locus_tag="NOA48_000853"
     CDS             19010..19915
                     /locus_tag="NOA48_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789138.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19912..20685
                     /locus_tag="NOA48_000854"
     CDS             19912..20685
                     /locus_tag="NOA48_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0789139.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20866..22290)
                     /locus_tag="NOA48_000855"
     CDS             complement(20866..22290)
                     /locus_tag="NOA48_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0789140.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22501..22947
                     /gene="nrdI"
                     /locus_tag="NOA48_000856"
     CDS             22501..22947
                     /gene="nrdI"
                     /locus_tag="NOA48_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI0789141.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(23012..24994)
                     /locus_tag="NOA48_000857"
     CDS             complement(23012..24994)
                     /locus_tag="NOA48_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0789142.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOA48_000858"
     CDS             complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOA48_000858"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI0789143.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25907..26968)
                     /locus_tag="NOA48_000859"
     CDS             complement(25907..26968)
                     /locus_tag="NOA48_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0789144.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27179..27745)
                     /locus_tag="NOA48_000860"
     CDS             complement(27179..27745)
                     /locus_tag="NOA48_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0789145.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(27773..29275)
                     /gene="eat(A)"
                     /locus_tag="NOA48_000861"
     CDS             complement(27773..29275)
                     /gene="eat(A)"
                     /locus_tag="NOA48_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0789146.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29533..30654)
                     /locus_tag="NOA48_000862"
     CDS             complement(29533..30654)
                     /locus_tag="NOA48_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0789147.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30780..31721
                     /locus_tag="NOA48_000863"
     CDS             30780..31721
                     /locus_tag="NOA48_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0789148.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31871..32767)
                     /locus_tag="NOA48_000864"
     CDS             complement(31871..32767)
                     /locus_tag="NOA48_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI0789149.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            33036..34376
                     /locus_tag="NOA48_000865"
     CDS             33036..34376
                     /locus_tag="NOA48_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0789150.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34594..35037
                     /locus_tag="NOA48_000866"
     CDS             34594..35037
                     /locus_tag="NOA48_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI0789151.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35541..36959)
                     /gene="nhaC"
                     /locus_tag="NOA48_000867"
     CDS             complement(35541..36959)
                     /gene="nhaC"
                     /locus_tag="NOA48_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI0789152.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37362..38585)
                     /locus_tag="NOA48_000868"
     CDS             complement(37362..38585)
                     /locus_tag="NOA48_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCI0789153.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38616..39455)
                     /locus_tag="NOA48_000869"
     CDS             complement(38616..39455)
                     /locus_tag="NOA48_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0789154.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39472..40152)
                     /locus_tag="NOA48_000870"
     CDS             complement(39472..40152)
                     /locus_tag="NOA48_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789155.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(40154..41227)
                     /locus_tag="NOA48_000871"
     CDS             complement(40154..41227)
                     /locus_tag="NOA48_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789156.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(41283..41521)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41564..41797)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41874..42545)
                     /locus_tag="NOA48_000872"
     CDS             complement(41874..42545)
                     /locus_tag="NOA48_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0789157.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42632..45310)
                     /gene="mgtA"
                     /locus_tag="NOA48_000873"
     CDS             complement(42632..45310)
                     /gene="mgtA"
                     /locus_tag="NOA48_000873"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCI0789158.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            45969..46406
                     /gene="ndk"
                     /locus_tag="NOA48_000874"
     CDS             45969..46406
                     /gene="ndk"
                     /locus_tag="NOA48_000874"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCI0789159.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46428..47294)
                     /locus_tag="NOA48_000875"
     CDS             complement(46428..47294)
                     /locus_tag="NOA48_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0789160.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
BASE COUNT        13766 a         9827 c         8308 g        15522 t
ORIGIN      
        1 aaaatcggaa taataactta tgtacttttt aattttgtta agtaatatat ctagttatat
       61 ctagttatat ctagttacct tttctttgaa aaaaacataa atcagctaat aaatatgtga
      121 gacaaagctg ccatccataa atactagctg attttttcag ttaaatgtct atttttttct
      181 ctgatgatgg tatttccaaa atattcccag tcatctggag tcggtggatt tttccaaatt
      241 atctgttctt tattaaattt ttcaagtaaa caatcagata aataaatatt cgtacgagaa
      301 gtgattcgac tctcaatcac aatattgtaa tttttaaatc ctttcacttg agaaataatg
      361 taatcggtat aagcagatcc ttgcgaaaaa tcaatacaga catgaatcgg tgcttcaaaa
      421 tatgataccg gacaaatacc gaccaataaa aagagataat cataaaataa gcgaatcatg
      481 aaacgttcat cttttcccaa gaaatagcgt ttattctctt gtatgacctt ttggattgct
      541 gtactgaata ttggatacgt ctcgaagaaa aactgtagct gctttttaga cgtaaagcta
      601 gtcatctcaa agtcgaatat ccaatttttt cgattgacat gcatcatacc catacgaagt
      661 tcttttcgta tatatagtct ttcttcttca gagatttcaa tcgaaaatgg taattgatca
      721 atcaattcca ctgacatttt ttgactaatc atgtggatat catgaaaatg agcttccgca
      781 agtccaaatg cgccatctaa ttcaaattct tcttccgtga tcaaaaacaa catgatataa
      841 gaaatctcat caatgatctg ctctttaggg atatgaagaa aagaaatatg tgataaatcc
      901 ttgatgatct tcattccttc tgagctctta aagtattcat ctgaaaagaa acgttttccg
      961 attggttgat tcccataggc cctcaacaaa ctaatagtgg ttagcaaatt gaatttgatt
     1021 cgttttgttg cagacagttt taaattgaac agatattcaa aatattgcac gatactcttt
     1081 gcttcattca tgacgctttc tctaaatggc atagaaaaac cattaaagac cccgaaatat
     1141 accccaaata atacgttccg tatgtttatt tcttccccaa ctaatatgtt tttctttaac
     1201 tttatttgat gctgttcaag aaaagagact aattctcttc tttttacata ggctcttgat
     1261 atgcttaaaa aatgattctc tgcaaatttt tcgatcgtta cttttgaatc cacgatctcc
     1321 gttaacagtc gagcaatttt tgatcgttga aagtagattc ttcttaaatt tttgatatcc
     1381 gtcaaattca gacgttcgac atggatctct gcttcttctg aaatttggat ctctggcttt
     1441 gttttgaatt cagtaaattc tttatttaat tctatgatat aatttcttgt tttaaattta
     1501 gacaaaccta atgtttcata taacttaggc agcactacat aattcttttt ctcaaattct
     1561 aaatatctag ctagcagcag tttttctcta tcttcctctt ctataaggta atccaacttc
     1621 atatcctaca cctcaaaaaa tgcctcatac caattacttg atatgcagat gaaagttcat
     1681 cttttcacct atactgattt tatgatggat tatgcttgtt ttttcatcag ttattctcat
     1741 tttttatctt ttttttgaga atattgcaaa aaatggaaaa atttatgagg aaatattcta
     1801 tattttttgt tttattgtgt taaaatgtac aagatttgcg ccatttgcgt aaacaaccac
     1861 aaaaaagagc aggacggcca ccgtcctgct cttttactta ttttaagttc cattacttat
     1921 taattggcta aacttctgct tgtttctgat attgcttgtt tttctccaat gatccgcact
     1981 tctgtttcta aagacacatc aaatttttct ttgattactt cttggatgtg cgcaatcaat
     2041 tcaatataat ctgtcgctgt cgcatgatcg atattgacga tgaatccagc atgtttttca
     2101 gagacttgtg caccgcccca tttcaggcct tgcaatcctg cttgttggat cagctgacct
     2161 gtatagtgtc ctactgggcg cttaaagaca cttccgcatg aagggtattc taatggctgt
     2221 tttgattgac gcaattcggt caactcatcc attcttgctt tgattgcttc ataatcccct
     2281 gtttgcaaac tgaatcgagc ttccaatacg atagcacgta attcttggac tttactgtga
     2341 cgataagaaa ataccatttc gtcttttgtc aaagttttca atgttccatc ttcaagcaaa
     2401 agatccactt cagcaaaaac atctttgatc tctccgccat acgcacctgc attcatataa
     2461 accgctccac cgacacttcc cgggatgccg caagcaaatt caaatccagt caatgattct
     2521 gccaaagctg cataagtcgt atcaatcagt gaggcacctg cttccgcaat gaccatcgtt
     2581 cctttgacat gaatctgttt catttcagtc agcatgatga ctacaccgcg aatcccgcca
     2641 tcttgaacga tcagattgct tgcatttcct aataccatcc aaggtatatc atggattcgg
     2701 caataatcga tgatttgctt tacttcttct tgttttttcg ggaatgcaag gacatcagct
     2761 ggtccacctg ttttcgtaaa cgtatagttc atcaatggtt catcaaacaa tatagtaatc
     2821 gtggctaagc tttcaactat ttcttcttta ttcactgagg attttccttt cttttctcaa
     2881 acgtcctcat tattctatca cgcttaatac aatcttgcca gtcttgttca aagttgatga
     2941 cggtagtgat ctttaagcac ttcctcacat aattcatgac ttcttacaac ttctttttgt
     3001 ttaagcaatt ctgtttccga tttacctaaa cggatctgag aaaagaaggc ctctaccatt
     3061 ggctcaaacc cgcgtttgac tagcgtgttt gtccagtcgc caaattcttt cacttttttt
     3121 ccatcagcat cttgaatgac aagctgggtc agatcgttta cttcataagt accattttta
     3181 cttgttactt gatatttttc tatattagcg ccacttgcta aatccatcgt taaaatagcc
     3241 gtttgatttt gtgtttctaa ttgtaaaatg gcatattcca aaaattcctt tgtttctctt
     3301 atctggtatt ttgttctcaa aatgggttca tctaataaat acacagctgt atcaataaga
     3361 tgtaaaaaca aatcataaag gacgaactct gtcgtttctt ttgccgctat tcgatttttt
     3421 tgcaggtgga tcaaccgctt atctgggata cgtttcaatt cttctaccat aggagcaaag
     3481 cgccggttga aaccgatcat caaaattatt tggttcttat cagctaattc ttgcaattca
     3541 cgaacttcat ttagatggac actcagtggt ttgtcaatat aaacatggat accattttct
     3601 agacattttt tggctaattc ataatgtact tttgttgctg cgtggatcat acatgcttcg
     3661 attttttctt ctaaaagctc atcgatcgtt tcatatagat gttggaaccc gtactctttt
     3721 tgaattcttt cttttgtttc tttatttctt gttgcaaaat aaaaatcaag tgttccttgt
     3781 tttttcgcat aagttggtaa atatgctttt tctgcgatat tccctacacc gattacacca
     3841 atcttcatct actttcctcc tggatcattt agttactttc atcttacacc attttttact
     3901 aaaatgaggt acaatagtat cgcaaaggta aggaaattaa ttcgaaggag tgtgctttta
     3961 ttgaaattta tctcttggaa cgtaaacggg cttcgtgcca tcgtaaataa aaatttttta
     4021 gaagtttttc atgagttaga cgccgatttt ttctgtctgc aggaaacgaa actccaagca
     4081 ggacaaattg atttagatct tccaggttat tatcaatatt ggaattacgc ggaacgaaaa
     4141 ggctattccg gcacagcgat ttttgctaaa aaaccagcat tgaatgccac ttacggaatg
     4201 ggtatcgata tccatgatac agaaggccgt ctgattactt tggaatattc cgatttcttt
     4261 cttgtaacct gttacacgcc aaattctcaa agcgaattaa aacgtttaga ttaccgatta
     4321 gaatgggaag aagcctttta taattatttg gaaaatctaa aaaaacaaaa accagtcatc
     4381 gtgtgtgggg atctaaatgt cgctcatcaa aagattgatt tgaaaaactg gaaaacgaat
     4441 caaaaaaatg ctggattcac tccagaagaa agagcggctc tttctcgact gttggataac
     4501 gggtttatcg atacattccg ttatttttat ccaacccagg aaggtgtcta ctcttggtgg
     4561 aactaccgat tcaattcaag gaaaaacaat gctggttggc ggatcgatta ctttttgacg
     4621 agcaaagatt tagagccagg actagctgat gcaaagatcc atacggacat tatgggcagt
     4681 gatcattgtc cagtagaatt agatttgaaa taaagaggtt gtgaaaaagt cgtttagttt
     4741 cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat tttgcataaa tttggcataa
     4801 taccgagaaa ctggcttttg aacactgttt atcgagagat tgtgaaaaag ctgtcctgca
     4861 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttgggctt
     4921 attaccgcag atacaagctt ttgaacaccg tttattaaga ggttgtgaaa aagctgcact
     4981 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg tttggttggg
     5041 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgtg aaaaagctgc
     5101 actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
     5161 ggacttatta ccgcagatgc aagcttttga acaccgttta ttgagaagtt gtgaaatcag
     5221 cgtcctgacc tgagtattag agaaacaaat ggcaaaatag ttcctcatat tttgctattt
     5281 tttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaag ttgtgaaaaa
     5341 gtcgcctact ttcgagtcgt aagaaatttt tttgaaaatg gttcctcaca actttgcata
     5401 aatttgactt aataccgaga agtcatgatc cccatctaac tccaaatcac aaggaatgag
     5461 ttcaaaaact agcttttctc aacaaatatt acataaaaaa ttctatgttt tttgttaaat
     5521 ttatttgctt ttttcaaaag tatgttacag taatttccca aggaggtttt acagaaatga
     5581 attttgttgc catggatttt gaaactgcca atcatcagcc ttatagtgct tgttctcttg
     5641 cgctagtcat ggtaaaaaat agccagatcg ttgatgaatt ctatacattg atacagcctg
     5701 agactccttt tttctggcga aatgtccaaa ttcacggaat ccatcaagaa gacgtacgca
     5761 atgcgccgaa attcccagaa gtctggcaaa ctatccaacc atattttcaa aaaaatcgtt
     5821 tagtcgttgc acataatgct gcttttgata caaaggtctt agcgggatgc ttagattatt
     5881 atcatcttga acagcctaat tatctttctt tatgtacagt gaaaagtagc cgtcgcctgt
     5941 ttcctgaatt tccaaatcat cgattgaaca ctgtgtgcga aaatttgaac atccaattag
     6001 atcatcacca tgatgcattg gaagatagtc gtgcatgtgc ggaaatcctg ctttatcaag
     6061 aaaaaaaatt cgggacagat ccattgaaaa aacttgtgac tataaagtaa aagaatactt
     6121 atgaaacaca caaagaggtc gtgagcctgc cgtttcactc cgagtcacaa ggagcaattt
     6181 caaaaaatag cttctcatgt ttattaaata ttgtgactgg tgaccgagga gctggcagga
     6241 gaacaccgtt tattggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     6301 caaacaaaaa tagcttctca tatttttcat ttggttggac ttattaccgc agatgcaagc
     6361 ttttggacac cgtttaccaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa
     6421 acaaacggca aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     6481 tgattgaaca ccgtttattc aaaaaaaatg gactgcgaca cgacttttgt cacagtccct
     6541 tcgtgtgttt ttctgccttc tcaaaaggat gacagtttct cactcttttc ctatttcttc
     6601 tattcaatca aataactcat tttatataca tctaaaaatt cacctagatc tgttcttgcc
     6661 cctctaggca tgaccgcttc gatttggaag cccatttttc ggtaaaggtg tacggctctt
     6721 tcattacgaa cttgaacgtc aagctccaat cgaaaaagta cacccatttc cttcgcccaa
     6781 ctgatgattt cttctagcat aagagtgcct agtcccattc cccaatattc ctgcagaata
     6841 ctgataccga cttctcccac gtgagacaaa cgaaattgac tgtctgcctt gacagatgct
     6901 gttccaataa tcgtcccttc atagattgca agcagcaata aattattatt gctttcgtat
     6961 atataatcca actcttcttc taaggtttct ggtggtaaca ggagttctgc ttcatccaaa
     7021 actaaaaatt ctgtctcctt attaacttgt cccatcatca aaagaatgtc ttttgcatct
     7081 cctggcactg cttcccgcaa gatgatccca acttcttcac tcatgatttt cagcccattt
     7141 ttctagaatt cgctgtttga aggtttcact ttgctccccg tatgagatta gtttcacata
     7201 ccgcttttct aaatctgtat cacttttttc taaaatcagt tccaaataat cctccggcag
     7261 tgcttcttct aatagatttc cccattcaac aacggaaagc ccatcacctt caaaatattc
     7321 atctaaccct aaatctgctc cgctagctgc tacccgataa atatccatat gatacaacgg
     7381 aatccgacct tgactatatt ctctaataat cgtgtatgtc ggacttttga tcatttgcgt
     7441 tatccctaat ccttgggcaa ttcctttcgt caacgttgtt ttacccgcac ctagatcacc
     7501 agtcaatatc agattgtcac ctggcattgc ggaatgacca attgcctctg cgaattgttc
     7561 tgtcattgtt aatcctgata gttcgatcat ttttcatctt ctcccgctct tctttctttt
     7621 tgccagtata tcgcgtaatg aagttttttt aaagaaaaaa tgaactagtc aagaacagca
     7681 gctgctgttt ttggctagtt cgcgtgtatt tgttaatcaa tcaatgtttg tgctgctgtg
     7741 ataatcgata atttatatac atcttcttca tttgctccac gagacaaatc agaaaccggt
     7801 ttgttcaagc cttgtagaat tggtccgatt gcttcaaagt taccgaaacg ctgagcaatt
     7861 ttatagccga tatttcctga ctgcaattct ggaaatacaa agactgttgc ttgaccagct
     7921 acttctgaat ctggcgcttt cagttgtgca actgaaggaa cataagaagc atcaaattgc
     7981 aattcgccgt cgatcatgta ttgtggcgct agttttttag cgattttagt tgcttcaact
     8041 actttgtcta cttctggcga tttcgctgag ccttttgtcg agaagctcat cattgctact
     8101 tttggttcga tatcgaacaa ttctgctgtt tttgcagaat ctacggcgat ttcagccaat
     8161 tcttgcgcag ttggattcac gttgatcgca caatccgaaa agacatattt ttcttgatct
     8221 cttccacgta ccatgatcat cgctccgctt gtccgactga tgccaggctt tgttttgatg
     8281 atctgaagtg ctgggcgaac agtgtcgcca gtcgaatgga tcgctccaga gaccattccg
     8341 tctgcaatcc ccatatacgt aagcatcgta ccaaagtaat tcacatcttt taaaatcttt
     8401 tctgcttgtt ctttggatgc ctttccattt ctacgttcaa caaaagtatc caccatttca
     8461 tcccacttat cgtaattatc agggctgatg atcgtaaagc tagatgtttt gattcctctg
     8521 gcatgcgctg catttcttat ttcttcttcg ttccctacta aaatgggttc cacaagttct
     8581 tctgctttca accgggcagc tgcgcctaaa atacgagcat cagtagcttc cgggaaaacg
     8641 attttgatcc cacggcgaac aattttaaat cttaaactat caaacaattc cacaagatga
     8701 cctccagacg tttttatatg tattatcata cactattcca gaaaaaaaga acagtttatt
     8761 ttatctgtat cagtcaaaaa tgctggaaaa attaagtttt tcacatacaa agcgaactgc
     8821 actataacag gaaagcgctg ttttattaca ctgtttcagg cagttgccaa tcaatcggtt
     8881 cttctcctaa cgcaaggagc gcatcattcg ttttcgagaa gggtttggaa ccaaaaaagc
     8941 cacgacttgc agataacgga ctgggatgtg gagatgttat gatgatatgg cgactcttat
     9001 cgatcatttt gattttttct tgtgccggtt ttccccacaa gataaacacg attggttttt
     9061 cccgttcatt taatttttca atgatcgtgt ctgttaatct ttcccaacct ttcccgcgat
     9121 gagaatacgc ttgcccttcc cgaacggtaa gaacggtgtt gagtaaaagg actccctgtt
     9181 tagcccatga cactagattt ccatgttgaa caggtgcgat tccaagatca tcataaagct
     9241 ctttatagat atttcttaac gatggcggga tctttacgcc aggttgcaca gaaaaagata
     9301 agccatgagc ttgattttct ccatgataag gatcttgtcc taaaatcacc actttaactt
     9361 cttcataagg agtcaattcc aatgcttcat agatatgata catatctgga tggatctttt
     9421 gggacgcata ttcttttttt aaaaattctc ttagatgcag ataataatct tttgaaaatt
     9481 ctgaggacaa aacttcttgc caactgttat gaatgatttc tttcaaaaac tccacctcct
     9541 aataaaaaga ataactcaca ttttcttcaa tcacaaggga caatcttcac cctcagcact
     9601 tgattaatat ggtaaactag gaacaagaag cagaaaggaa cgataatcat tatgatcaaa
     9661 ttaattgcat cagatatgga cggcacatta ttagatgccc atatgagtgt ttctcctgaa
     9721 aatgccgagg cgatacgttt tgcaaatgat gccggtgttg agttcatggt cgctactggt
     9781 cgaaactatc aagaagctcg cgcagcttta gatgaggtag gaatcgattg tgcgatgatc
     9841 actttgaacg gggcacaggt atttgataaa gaaggaaatt cattgtttac cgtgtcgatt
     9901 ccaaataatc aagcaatctc tgttttagat attctagatg ctaacggtat ttactatgaa
     9961 gtagcaacca acgatggtct ttattctgaa aatcaagcga aacgaattga aagttttgct
    10021 tccatggtgg ctacccattt acctcacctt acgtataaaa tggcgattgc catggcctca
    10081 gctaagctgg agttattgca catcacatac gtggacagta ttcgtgctat tttggaagaa
    10141 aagaatctgg aagttttaaa aattatttgt tttcatacag aagggccagc tgtattaggt
    10201 ccagttggaa agcagatttc tcttttaggc gatctagccg ttacttcctc tggtcaaaac
    10261 aatatcgaag tgaaccataa aaacgctcaa aaaggaattg ctgttgccca tgtcgctcac
    10321 gagcgtggga tttctttaga agaagtcatg acgattggcg ataacttcaa tgatgtcagc
    10381 atgctgcaag tagcaggagt cagtttcgca atgggaaatg cagaaatcga agtaaaagat
    10441 tatgccaaat atacaacgga cacaaacctt gaatctggcg taggaaaagc catattgcgc
    10501 gcgattgcag aagacttgta gttttatcta gaaaagaggg atatagatgt cagaattttt
    10561 cattcaggaa aagcagcttg gacgtgcaac tcggacaatt gtcaaaaacg aaaaaggaca
    10621 ttccctgttt ttgatggttg gtcgctgggg aacaaagggc gatgcattgt ctctttatgc
    10681 catgaatggc gatctcgttg ctcacatcaa gcagataagc ctgacattcg gtacgcgttt
    10741 tgagctgtat aaagagttcg aaaaggtggg aaccatgcag aaaatattca attggcccgg
    10801 tgacttttat tatattcgta gacttcactg gacagtccaa ggtgatatct ataatcatca
    10861 atatcaaatc catcatttca atcagcaaat catgaaaatg gataaagcaa cacttttttc
    10921 aggagattac tatgtattgg atgtctcaaa tgatgaagat gctccagttt gtatttgtat
    10981 tgctgcggtt ttagattact ggctctaccg taaagacaaa agtcgcgata agcctgtttc
    11041 ttaccgactt aacttaagtt aaaaagatgt acctgaaatg cggaaatacg catttcaggt
    11101 acatcttttt agatattctt ttgcatatga tcataaagat gaccactgat catccgctga
    11161 ccgacaactt tgaagtcatg gcgttcgtat aattttttag cctttggatt tttttcatcc
    11221 acacttagac cgatgacgga gcgattagct ttcttcgcca atttaggtaa tgcttctaat
    11281 aatcgcgaac cgatgccttg tcctctaaaa tcttctgata cactgataga gtccaaatac
    11341 cattcgttgg gaaacgtttc tttatcaatg aacaaacgtg tagacgcatc tagctgatat
    11401 ttctctaaga taggtaccag tggctgatcg atgattgatt cttcttcatc tgtataaccg
    11461 taagcaactc ctgcaacttt accgtctatt tcttctacga tacctcgtga ataactgtaa
    11521 cgataatttg gatcagtgat tgcttcttct aaaatctcta aagtcttttg ttcccctgtc
    11581 tgcttcaaaa atggcagttc catatctttt agaatcacta agatcaatgg ggcgatttct
    11641 ggagcatctt cttttctcgc aaaacgaatc atagtttcct ctccttttct ccattctaac
    11701 atgcagaaaa agaaatcgca aaatcgttat tttaaaaaat cttcaatctt ttcagtaatg
    11761 aaataaccat gagtaacgat tcttgccgct tcagttcggc aataagggca gacgactggc
    11821 atttctttat cattatgttc gactacatta ttgacttctt cgtatgcaaa tttttttccg
    11881 caattagggc atttcatttt ttccatgtta tctcaacttc ctttcatctt tactctctta
    11941 gcttactctt atattgtaaa aaagagaagc aatatccttc ttctatgcag atatccatac
    12001 ctgacggtcc tgttctccat ctattaatcg gactttataa taaggacgtt catctttgac
    12061 tagaagtgtc cactctttca cttttgcttt tttcccgtag tagctgactg cttccttcat
    12121 cgctgcttgc ggttgtttga actcttccgt tttttctata tcaaaaagat gttctgcggc
    12181 cttttccgtg tcatttcgta cggttgtttt cccagtggat ggattgactg ctatgacttg
    12241 tccttcacaa aaaaactggt attcatatgt tgcattcgta ggattctcca aatctttttc
    12301 aactgcaaaa tgaatagcag atatgttatg ttcttttgtt tcgtttttta cgattgctgc
    12361 tgcttttttc aatgagatcc gatattcctg gtcactaata tcatccatgt gaaaagcggc
    12421 attgagcagt cccgtcatac cggtaatccc tattacgatg agggcagcaa caccaaacat
    12481 catttttttc attcttcatt ctcctgtttc ttttttttaa agaatatcaa gaaatgaacg
    12541 aatgaaaaat cgaatgaaac gaaaaaaaag tgacaatttt gttatcttta ttcgtgcagt
    12601 tctaatggca atccgtctgg atcaaagaaa aacgtcattt tttttcctgt aaaggtatct
    12661 tctctaatcg gttctgattc gatccctaag gactgcaatt ctgcaattgt ttcttcaata
    12721 tcgtctactt tgaaagcaag atgacgcaag ccacaagctt ctggatagtt tggtcgttgt
    12781 ggcgcattag caattccaaa aatctccaat tcagcacttc ctagtttcag atctaattta
    12841 tagtcatctc gttctttgcg gtaattttct ctgattactt caaatcctaa tttattaaca
    12901 taaaaatcac gtgatttctg ataatctgaa acaatgatgg ctatatgatg gatcgttgta
    12961 aggttcatat gagcactcct attcttcgtt taagctcgga tctatattaa tctccagttc
    13021 cattgtaaat gtgtcagatt gaaaaaaata gctgtttttc ctttttataa gaaaaaaggc
    13081 aaaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    13141 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    13201 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    13261 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    13321 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    13381 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    13441 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    13501 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    13561 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    13621 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    13681 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    13741 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    13801 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    13861 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    13921 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    13981 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    14041 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    14101 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    14161 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    14221 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    14281 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    14341 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    14401 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    14461 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    14521 agaacccttc tgtaaaacca tagcgacaat attgcttcca aataaataga tagatttttg
    14581 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    14641 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    14701 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    14761 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    14821 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    14881 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    14941 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    15001 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    15061 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    15121 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    15181 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    15241 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    15301 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    15361 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    15421 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    15481 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    15541 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    15601 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    15661 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    15721 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    15781 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    15841 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    15901 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    15961 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    16021 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    16081 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    16141 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    16201 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    16261 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    16321 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    16381 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    16441 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    16501 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    16561 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    16621 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    16681 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    16741 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    16801 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    16861 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    16921 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    16981 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    17041 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    17101 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    17161 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    17221 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    17281 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    17341 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    17401 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    17461 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    17521 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    17581 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    17641 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    17701 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    17761 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    17821 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    17881 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    17941 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    18001 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    18061 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    18121 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    18181 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    18241 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    18301 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    18361 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    18421 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    18481 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    18541 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    18601 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    18661 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    18721 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    18781 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    18841 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    18901 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    18961 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    19021 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    19081 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    19141 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    19201 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    19261 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    19321 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    19381 aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    19441 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    19501 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    19561 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    19621 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    19681 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    19741 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    19801 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    19861 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    19921 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    19981 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    20041 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    20101 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    20161 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    20221 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    20281 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    20341 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    20401 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    20461 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    20521 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    20581 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    20641 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    20701 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    20761 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    20821 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    20881 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    20941 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    21001 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    21061 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    21121 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    21181 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    21241 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    21301 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    21361 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    21421 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    21481 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    21541 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    21601 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    21661 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    21721 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    21781 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    21841 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    21901 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    21961 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    22021 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    22081 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    22141 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    22201 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    22261 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    22321 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    22381 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    22441 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    22501 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    22561 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    22621 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    22681 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    22741 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    22801 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    22861 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    22921 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    22981 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    23041 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    23101 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    23161 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    23221 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    23281 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    23341 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    23401 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    23461 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    23521 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    23581 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    23641 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    23701 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    23761 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    23821 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    23881 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    23941 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    24001 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    24061 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    24121 agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg atgatatcta
    24181 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    24241 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    24301 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    24361 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    24421 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    24481 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    24541 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    24601 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    24661 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    24721 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    24781 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    24841 cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc acacgagtca
    24901 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    24961 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    25021 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    25081 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    25141 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    25201 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    25261 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    25321 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    25381 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    25441 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    25501 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    25561 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    25621 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    25681 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    25741 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    25801 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    25861 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    25921 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    25981 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    26041 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    26101 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    26161 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    26221 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    26281 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    26341 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    26401 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    26461 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    26521 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    26581 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    26641 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    26701 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    26761 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    26821 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    26881 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    26941 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    27001 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    27061 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    27121 cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt
    27181 actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca
    27241 tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga
    27301 cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta
    27361 agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct
    27421 catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa
    27481 cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa
    27541 gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt
    27601 tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc
    27661 cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt
    27721 cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag ggttagattc
    27781 tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta
    27841 gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat
    27901 ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag
    27961 ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat
    28021 ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt
    28081 tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa
    28141 tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa
    28201 gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat
    28261 gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat
    28321 cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga
    28381 tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca
    28441 cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca
    28501 ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg
    28561 aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca
    28621 atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag
    28681 agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta
    28741 cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca
    28801 aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta
    28861 acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc
    28921 ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct
    28981 ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac
    29041 gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc
    29101 cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc
    29161 gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata
    29221 atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc
    29281 atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt
    29341 tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac
    29401 actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt
    29461 tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa
    29521 tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat
    29581 ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa
    29641 atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact
    29701 tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg
    29761 aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc
    29821 ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat
    29881 cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat
    29941 atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt
    30001 atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc
    30061 tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga
    30121 aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc
    30181 tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca
    30241 cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat
    30301 aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag
    30361 tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt
    30421 tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg
    30481 ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat
    30541 cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag
    30601 ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat
    30661 ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta
    30721 ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca
    30781 tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc
    30841 aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta
    30901 caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt
    30961 caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag
    31021 ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg
    31081 ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga
    31141 aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca
    31201 cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta
    31261 caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg
    31321 ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga
    31381 ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa
    31441 caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag
    31501 aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg cattacccat
    31561 ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg
    31621 ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc
    31681 aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat
    31741 cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca
    31801 caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa
    31861 tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag
    31921 tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct
    31981 ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt
    32041 ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat
    32101 ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct
    32161 gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt
    32221 cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg
    32281 taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat
    32341 tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg
    32401 aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat
    32461 aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt
    32521 tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag
    32581 ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt
    32641 gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag
    32701 agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt
    32761 tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata
    32821 gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat
    32881 atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa
    32941 ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa
    33001 attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac
    33061 aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat
    33121 ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga
    33181 ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg
    33241 gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg
    33301 attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg
    33361 cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta
    33421 tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag
    33481 aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt
    33541 atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg
    33601 accatggtgg gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta
    33661 tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta
    33721 aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca
    33781 ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca
    33841 gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt
    33901 ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa
    33961 ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca
    34021 agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag
    34081 ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata
    34141 cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag
    34201 gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc
    34261 ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt
    34321 tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc
    34381 gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg
    34441 acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac
    34501 ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag
    34561 aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg
    34621 atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc
    34681 gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg
    34741 gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg
    34801 atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact
    34861 actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg
    34921 gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt
    34981 caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca
    35041 ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa
    35101 gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta
    35161 ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg
    35221 cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga
    35281 gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac
    35341 cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg
    35401 cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata
    35461 ccgagaaact ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca aaagtcttgt
    35521 cacaatccct ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc
    35581 ggtttcacaa atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca
    35641 ggagaaagca aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta
    35701 cttgctacga aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca
    35761 tcttctagcg ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta
    35821 aatgcattac caggcagaat aacagatagg aattgttcac caataaaaat atttactccg
    35881 atacttgtca tcaatgttgt aaaaatcaaa tttggtgtgt tcgtcatctt tcttgatact
    35941 cgttccatca cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt
    36001 agaataatca atgacacagt aggcatcata ctttcgattc ctccgcggct aagcagtgaa
    36061 tcgatttgtt ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc
    36121 gttaaggaag tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac
    36181 aaaatcgtta aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga
    36241 atcagtgacc agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata
    36301 gatgaaagac ttgcggcttt acttgtgtgt cctaaaatca tgaataaaaa gaaagaaaca
    36361 acaaatgccg ggacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca
    36421 acaatagctg ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg
    36481 gcacctgaaa caatagctcc aacaaccagc gctggattta agcctagtgt tgtcccaata
    36541 ccgaaaaatg caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct
    36601 acgattgcac acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac
    36661 ccaatgacca ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaaccg
    36721 actaaaataa aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg
    36781 tgcagccaat ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct
    36841 gctaagatcg tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa
    36901 acaataacca ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg
    36961 ataatctctc cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc
    37021 cgccgcaatt catccgcgat tcctccttta taaaaataaa aagacctgtt ttaaactaag
    37081 gacgaatgac tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact
    37141 tttattcaaa tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc
    37201 gaccaccgac tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtacg
    37261 aagtttacct tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg
    37321 aaaattattt ttataacttt cacacacaag tttatttttt actagaaagt agcgccctct
    37381 tgtttttttc ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc
    37441 tctttcaaca gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca
    37501 aggcctttgt cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc
    37561 tcagagattg ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca
    37621 gaagaaccga gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct
    37681 tttgcatgct ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca
    37741 ttttggaaca atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata
    37801 ttttccactt tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa
    37861 cgtccagcag cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca
    37921 tggatattga catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg
    37981 atcaatgctt ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca
    38041 ccgtaaaatt tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga
    38101 aaagctggat ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag
    38161 ctgcctttag ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt
    38221 tctccaccag tttcatcaat gaattgcttc actatgctgg cggctaatac ggagtaagta
    38281 ccaaacaaat tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa
    38341 aaggcaattg tgggaccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt
    38401 ccagctactt ctttttctac ccaaaacctt tctttttcta attgtttaat caacgctgct
    38461 gaggaataaa actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct
    38521 tgatattctg gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt
    38581 gtcataaaaa attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat
    38641 gcaggcacgc ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga
    38701 taagcgtcta ctattttttg atacgtttta ttgttttcat cttcttttct tgcaacgatg
    38761 atattcacat aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca
    38821 ggattaaatc cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac
    38881 aaagcacgtg ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg
    38941 gtaatatcag aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca
    39001 gtttgcaata acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt
    39061 gctccgtctt tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca
    39121 ttgacagtat ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa
    39181 aagaattgat gttggaaaga attcaaatca atcgatccat ctgctaaagc cacatttggt
    39241 tgattgtaat ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct
    39301 ttcacgttgt cccatacatc tgtatcttct ccaataatcc ctagttttac gatagtttct
    39361 tttttgtcag ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca
    39421 aatgtaatga ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt
    39481 aattttttta atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa
    39541 taatgtagcc acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag
    39601 attccctaat ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat
    39661 gatagtcaac gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa
    39721 aatgataccg attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac
    39781 ttctagcagt gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg
    39841 cactaaagct gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa
    39901 aagagaaagc aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat
    39961 ttcaaatagc agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc
    40021 taagatgatt ccaatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg
    40081 cttcgtcgct tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa
    40141 gaaatcagtc attttatctt cctccttcga tcactttgat acgactatct aaatcgtttt
    40201 tttgtaaaat atttattttt acaccagatt tgatcaaata atccaatgct tttttccgct
    40261 gtttggtttc tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact
    40321 ctacattgcc atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta
    40381 gaggttcgtt cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct
    40441 gatcggcaaa agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg
    40501 ttcgaataaa atctttggtc aattcttctt caggattgct gaagatctgg atgctgctac
    40561 ctttttcaac gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa
    40621 cttgcatctc atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta
    40681 acaatgcaag gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata
    40741 ataatacctt aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc
    40801 ccgacagttg tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt
    40861 cattcacttt ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa
    40921 cgttgtcaaa aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg
    40981 cctttctttc ttttcgcaat tctttgggag agagctgact cagattcgtc tgattgacaa
    41041 tgacttctcc tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc
    41101 ctgcacctga gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag
    41161 aatctactgc ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt
    41221 caatcattaa aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt
    41281 ttcttgagga cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac
    41341 tcctcttcaa gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca
    41401 tctatgctcg ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct
    41461 cagctaccga agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata
    41521 atattcaaaa aaaaagtcct tttactaaca taaactatgt cagtaaaagg acgacgtatc
    41581 gcggtaccac cttttttcgg aagtttcctt ccctcaagcc caacatctct aaaagagaga
    41641 ttggcgttcg ttttaacggt cgaacagttc cgaatttgcc tacttatcga caaattattc
    41701 tccaaggcca ttttcagctt ttcttacttg actcttctca ccagccagag cctctctgca
    41761 aagtttccaa acttactttc cttttcaacg aaatcgatat tttgttgttg ggattaatct
    41821 acatgaggaa aactgaaaag tcaagtacga aattcaaatt attttttcta tatttatttt
    41881 tctgtttttt tatttaacat ttcaataaca gttcgaagat cttttccttc cgcaagaagt
    41941 ttcaattttt ccttttcttc gacggtataa tttcggacaa aactggaatc aggtatcaaa
    42001 acaacgccta atcctgctcg tgaagcagct gttgctccta ctaaagaatc ttccactgca
    42061 aaggctgaac tagcttctaa tcctgttcgt tccaaagctg tcagataagg aatcggtgaa
    42121 ggcttgttct ccgacacttc gtctccgaat gtaaacgtgt ccaagtaatc agctaattta
    42181 aagtgatcca agatatctgt tgctcttttc gtaacagtgg tcgtagcaat gcctagtttc
    42241 atatgacgtt cttttaagtc tgccaatatt tcttttgcat atggttttaa gtggatggct
    42301 ccgcttgtca gctgttgata aaaatattct tcacgcttcg ctcggacttc ctgtactttt
    42361 tcagggctac ctgctgcttt cactaaaata tcaaaacttt gtttccagtt ttttcctccc
    42421 caagcgtcaa cgatttcttt tgggatatgg atatcaaatt gctgaaatcc ccaaagccag
    42481 ccatcacgat acgttttttc tgtgtcaact aacaaaccat ctaaatcaaa tattgcacct
    42541 ttcatctata cattaatcct ttccaaaaca atacacatag tttagcacga ctggtccaaa
    42601 aagaacagaa gcaaagaacc agccttctcg tttataagag ttcttggaat cgacggatat
    42661 agattttctt cacagctgtc acaagcgcca gataagcgat gactgtagca aataaccata
    42721 accagtaatt gccaggaagt ggcatcaagc ctaattcagc accaaaactt gtaaaaggaa
    42781 ggacagaacc gacaataatt cctaatgtag tgataacaaa catggcaaat gttgcgttgc
    42841 tttggataaa tggtactttc ggtgtacgca gtgcatggag cactaaggtt tgtgtccata
    42901 gtgattcgac aaaccatcct gcatggaata atgcgatgaa aatcactcgc tgtgaactat
    42961 ccaatgtatg gaaacttccg cccactacag caggacaaat aacaaaatac atcaacaagt
    43021 aagtagtaat atcaaatatc gaacttgttg gaccaaagta aaccatgaat tccccaatac
    43081 tagatgcatt ccattttttt ggctcgtcca aatattcttt atccatccga tcccatggca
    43141 aggaaatgca ggaaacatca tagatcagat tcaaaaacaa aagttgtaaa ggcagcattg
    43201 gtaaaaatgg caggaacgta cttgcaatca gcacggaaaa catattgcca aaattagaac
    43261 ttgctgtagc cttgatatat ttcatgatat tcccaaaagt ttctcgtcca gaaagaaggc
    43321 ctctttccaa aatcgtcaaa tctttttcta aaaggatcac gtctgcagat tctttcgcaa
    43381 tatccacagc tgtatctaca gaaataccga tatcagccac tttcattgca ggagcgtcat
    43441 tgataccatc tcctaaaaat ccgacagtat gaccattttt acgtaaagct gtcgtcaaac
    43501 gtgctttttg ctgaggattc aattttacga atacttcatg gtcttcagct acttgtgcta
    43561 attcatgatc actcatttcc gagattttct caccggtaac caattcattg atctctagac
    43621 ctacttgacg gcacactgaa cgtgtaacta attcgttgtc cccagtcaga acttttacag
    43681 ctacaccatg ttctttcaga gctttcaacg cttgtttcgt tgtttctttt ggtggatcaa
    43741 ggaaagcaag ataaccaatc aaaaccatgt ctgactcatc tttgactgaa aattctccaa
    43801 cgacgcttgg attggtcttt tgtgcgacac caatcactcg taagccatct tcattaagtg
    43861 actgtacttt tgcaagtacg gcttcttttc gttcttttgt taatggtgta acagtaccgc
    43921 caagatcaat aaatttagaa atgttcagca tttcttcaat cgcgcctttt gtgatcattt
    43981 gtgttttacc agctggatca gcaaccacaa cactcatacg acgacgttca aaatcaaaag
    44041 gaatttcatc cactttttga taattgatct tatctgtatc taaagtttct gttgcttcat
    44101 caatgatagc cacatctaac aaatttttca gccctgtttg atagtagcta tttagatacg
    44161 catggcgcaa aacacgatca tcttcatttc cttcacaatc catatgatat tcaagaatga
    44221 ttttatcttg tgtcaatgtc cccgttttat ccgtacataa cacatcgatt gcaccaaagt
    44281 tctggatggc attcaaattt ttgatcactg ttcctttttt ggccatcaca cttgctcctt
    44341 tgaccaaatt cgtcgtaacg atcattggaa gcatttcagg tgttagacca actgctacag
    44401 atagtccaaa aagaaaagct tctagccaat ccccttttgt aagcccattg atgacgataa
    44461 ctgctggagc catcaatgac ataaatttga tcagtagcat ggatgtttta tggatgccta
    44521 attcaaagct tgattgaatt ggtttttcag atagcgtttc tgctacatga ccaaatagtg
    44581 tttcatttcc aacagaaaca atgattcctt ccgcacttcc actgatgaca ttacttccca
    44641 taaagacaag attttcgtaa cttgtttcgc tttgctgatc gtcttcacat actttcgcat
    44701 gcttttctac tggatagctt tcccctgtca atgctgcttg ggaaatgaat aaatcctttg
    44761 cggacaataa acgcatatcc gctggtatca tatcccctgc tgaaagccga acaagatctc
    44821 cacagacgat ttcttccata ggaatctctg tgtactttcc attacgtttt acagctgccg
    44881 ttactttcac aagtgatttc agtttttcag ccgcttgatt ggaacgtacg gactgaatca
    44941 acgtcattgt cccgctgacg ataaccatag tgaagataat ggctacaccg aaaagatctt
    45001 tatctccagg agctgctaat acatattccg tgatgaatga aataattcct aatgcgatca
    45061 acactaatgt aaatggcgtg atgtatgctt tcaatatttc tacaatgaat ggtgtttttt
    45121 tgccatatga aatcgcattt tcaccgtaat tttctcttga acgttcgatt tgttcttctg
    45181 tcaatccatt tgctgatgca tggaatagtt caaataattc ttgtttcgtt tttccagcaa
    45241 aagctgcata gattttttgt gtatctttct ttttttccat ctcaatctct cctttgtgtc
    45301 caaaagacag ctgttctcgc tgcttttggt ctttagctat tcatcggatc gatagagaaa
    45361 aaactgaaag gggctgagaa cagatagata atagccctgg cctttcctct agatccttgt
    45421 ttttcgaatg actgtcatcc atttgttctc atctccttta ctaagtaatt ttaattcatg
    45481 acttccaatc atttttcgaa tagttatttt tccaattaga ccacctcctt tttatttttc
    45541 accgatgggg atttgcggca acaaaaaaac ctctcgccaa atactcagcg aaaggtttga
    45601 aaaagcatat taaaaaaagc ttctcagatc tcatcgttga gttttgacac tgtacaacgt
    45661 aaaaagcaga tacctgcttt tagctacctt atgaaaagcc ttatctcgac aattcctgtt
    45721 ctacccattg gcgtctctcg acgtttttgg gcagtagcct atgtttgtat aggagcctca
    45781 cctaacaaat cttattcggt tttccttcgt taatataaca actaaaaaag aggatgtcaa
    45841 atcaattttc catgtttttc atactttttt taaaatacac acgttatatt cctgtctcac
    45901 gcggttttat ttgtctcatt ttccacctcc cgctataata gaaatatagt aggaaacgag
    45961 gtgctgttat ggaaagaaca cttgttatta tcaagccaga cggcgtgaga cgccatttag
    46021 tcggaagcat catccaacgt tttgaagcaa agggactggc cattgctgaa atgaagtttg
    46081 aaactatgac tcctgaatta gcaaaagaac attatcagca cttgactgag cgcagttttt
    46141 ttgatgaact gatcgattac atgacttccg gtcctgtcgt ttatcttgtg ctggtcggcg
    46201 aggaagtgat cgatatcgtc cgtaagatgg ttggagcaac aaaagctgcc gatgctgttc
    46261 caggtacgat ccgaggagac tacgcgctgc cggggactga aaacatcatt cacgcttctg
    46321 attcccgtga tgctgcggta aaagagatcg cccgcttttt cccgccattc gatataaaca
    46381 aaccgtctga aaaagcggcg aagtgataca aattctaaac tgctggtcta gttgctgggt
    46441 tcagcaatgg ccagcagttt tttctctaag gacctccgtt gattctttcc taacatatat
    46501 tcgagcactg tgaagaattc ttggtagtct ttcgtctttt cttcccctaa agcagcagaa
    46561 atcaatcttt gataataatc tgccatcaat gtttcataga tcactgtact tctttcttta
    46621 tgtgctaagc tccgtttcat atcttcattc acactacgtg cctttttcaa ccgaccattt
    46681 tctatataaa acgaagtcag gttcattaaa aaagtaaaga gatactgctc atgattgttc
    46741 aactgtgcta atcgtcgcat tctttttttg attttcaaat aattgttctc aatgaaccga
    46801 tcactgaata tccaaggaaa atcagctaga atagatagtt caaattgacc atagtctggt
    46861 atctgcatca agtattcttc aatgattcgg cattcataac gtaaaaattc aaattctgtc
    46921 tcagatactt ctgttttttc gaccatgtga agattcaaaa ccaaataata cagatcttct
    46981 gttttcttaa aatgcctacg gttattgctg atctctttat aaggatcaaa gctgtcttct
    47041 tgtacccgat ctagcattcg tctttttttc tttaacttta ttggttcatc cagctggttt
    47101 cgcatccatt catattctgc aagtgtcatg ttcattcgct ctaaaaatga tctcaatgtt
    47161 acaaatgaca tttttttcac tgaatttgtc tcaatcccga ctagagaagt cttaaaacag
    47221 attccttccg ctaattggga ctgtgtcaac ttcttgttga ctcgaagttt cttgatcaat
    47281 tcaccatcat acataatagt tctccttttt aatttaaatt tttccacatt caataaatag
    47341 atacgttaaa aaggaaaaat acacgaaaaa aataaaaaaa tgtttttttc ataaaaaata
    47401 ccaaccttca agcattagaa tgt
//
LOCUS       DAIGQM010000016        43085 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.016, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000016 DAIGQM010000000
VERSION     DAIGQM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.016"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..2498)
                     /locus_tag="NOA48_000876"
     CDS             complement(<1..2498)
                     /locus_tag="NOA48_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789161.1"
                     /translation="MKIIGKKIANRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TKSQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLSTIVVGLMILSLVIVGYKMIIGKGTVDLKSVGMNVVMSISLI
                     LLMPTLIHSGIEFSKTFYNDSTTITDSDEGVAWSLIEQGVTDLAYINKTDQYSMIDKT
                     NDRNNLTKENFWKTDLTQVLTDNVLDKMEKENPIADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMASERATK
                     PFKSMRDIANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNTNHASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEIMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQDRRSVDVRENLQNTTSSQSGNRIVDVRENVQSSASNQSRTVDV
                     RENLQNTTSSQSGNRTVNVRENVLSSGTSQPRTVDVRENLQNTTSSQSGNRTVDVREN
                     VQSSTSSQGFKTVDVRENVQKDSGEMKEKAQKIN"
     gene            complement(2723..3592)
                     /locus_tag="NOA48_000877"
     CDS             complement(2723..3592)
                     /locus_tag="NOA48_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HCI0789162.1"
                     /translation="MAEKRMLSKTFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYVKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKLDVILKSGQVEPLRVDLMEKWYPVGIPSINHLEVQSSQDQISSDK
                     SSLVKNSIDKINQVDTIINEEIINEKGIQLIHKLGDRFTKSQREKFVQLIVDMKNSTE
                     REFKIRIDGPHYYEQTNKMIIRLFNTINEKLNLGKELNEMKYVNTVSRNHWKEIALEE
                     QDNRMYIIDALSK"
     gene            complement(3746..4048)
                     /locus_tag="NOA48_000878"
     CDS             complement(3746..4048)
                     /locus_tag="NOA48_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789163.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGESFERK"
     gene            4250..5047
                     /locus_tag="NOA48_000879"
     CDS             4250..5047
                     /locus_tag="NOA48_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0789164.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            5098..6240
                     /locus_tag="NOA48_000880"
     CDS             5098..6240
                     /locus_tag="NOA48_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789165.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENYSVKMYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(6338..7729)
                     /gene="sufB"
                     /locus_tag="NOA48_000881"
     CDS             complement(6338..7729)
                     /gene="sufB"
                     /locus_tag="NOA48_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCI0789166.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(7734..8204)
                     /locus_tag="NOA48_000882"
     CDS             complement(7734..8204)
                     /locus_tag="NOA48_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCI0789167.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(8191..9426)
                     /locus_tag="NOA48_000883"
     CDS             complement(8191..9426)
                     /locus_tag="NOA48_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0789168.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(9423..10709)
                     /gene="sufD"
                     /locus_tag="NOA48_000884"
     CDS             complement(9423..10709)
                     /gene="sufD"
                     /locus_tag="NOA48_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCI0789169.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(10722..11495)
                     /gene="sufC"
                     /locus_tag="NOA48_000885"
     CDS             complement(10722..11495)
                     /gene="sufC"
                     /locus_tag="NOA48_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCI0789170.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(11692..12540)
                     /locus_tag="NOA48_000886"
     CDS             complement(11692..12540)
                     /locus_tag="NOA48_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0789171.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(12564..13250)
                     /locus_tag="NOA48_000887"
     CDS             complement(12564..13250)
                     /locus_tag="NOA48_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789172.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(13243..14277)
                     /locus_tag="NOA48_000888"
     CDS             complement(13243..14277)
                     /locus_tag="NOA48_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789173.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(14340..14596)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14672..15010)
                     /locus_tag="NOA48_000889"
     CDS             complement(14672..15010)
                     /locus_tag="NOA48_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCI0789174.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(15012..15368)
                     /locus_tag="NOA48_000890"
     CDS             complement(15012..15368)
                     /locus_tag="NOA48_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCI0789175.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(15374..16561)
                     /locus_tag="NOA48_000891"
     CDS             complement(15374..16561)
                     /locus_tag="NOA48_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0789176.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(16752..17597)
                     /locus_tag="NOA48_000892"
     CDS             complement(16752..17597)
                     /locus_tag="NOA48_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0789177.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            17831..18796
                     /locus_tag="NOA48_000893"
     CDS             17831..18796
                     /locus_tag="NOA48_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCI0789178.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            19173..20216
                     /locus_tag="NOA48_000894"
     CDS             19173..20216
                     /locus_tag="NOA48_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCI0789179.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(20278..20742)
                     /locus_tag="NOA48_000895"
     CDS             complement(20278..20742)
                     /locus_tag="NOA48_000895"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCI0789180.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            20988..21935
                     /locus_tag="NOA48_000896"
     CDS             20988..21935
                     /locus_tag="NOA48_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0789181.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(22146..24218)
                     /locus_tag="NOA48_000897"
     CDS             complement(22146..24218)
                     /locus_tag="NOA48_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0789182.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(24151..24528)
                     /locus_tag="NOA48_000898"
     CDS             complement(24151..24528)
                     /locus_tag="NOA48_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCI0789183.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(24657..25235)
                     /locus_tag="NOA48_000899"
     CDS             complement(24657..25235)
                     /locus_tag="NOA48_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0789184.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            25367..26659
                     /locus_tag="NOA48_000900"
     CDS             25367..26659
                     /locus_tag="NOA48_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0789185.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(26719..27837)
                     /locus_tag="NOA48_000901"
     CDS             complement(26719..27837)
                     /locus_tag="NOA48_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCI0789186.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(27851..29272)
                     /gene="arcD"
                     /locus_tag="NOA48_000902"
     CDS             complement(27851..29272)
                     /gene="arcD"
                     /locus_tag="NOA48_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCI0789187.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(29518..30639)
                     /gene="mnmA"
                     /locus_tag="NOA48_000903"
     CDS             complement(29518..30639)
                     /gene="mnmA"
                     /locus_tag="NOA48_000903"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCI0789188.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            31043..31642
                     /locus_tag="NOA48_000904"
     CDS             31043..31642
                     /locus_tag="NOA48_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HCI0789189.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(31780..33066)
                     /gene="efmA"
                     /locus_tag="NOA48_000905"
     CDS             complement(31780..33066)
                     /gene="efmA"
                     /locus_tag="NOA48_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCI0789190.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(33337..33681)
                     /locus_tag="NOA48_000906"
     CDS             complement(33337..33681)
                     /locus_tag="NOA48_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCI0789191.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(33818..34963)
                     /locus_tag="NOA48_000907"
     CDS             complement(33818..34963)
                     /locus_tag="NOA48_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0789192.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(35143..36117)
                     /locus_tag="NOA48_000908"
     CDS             complement(35143..36117)
                     /locus_tag="NOA48_000908"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0789193.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(36197..37072)
                     /locus_tag="NOA48_000909"
     CDS             complement(36197..37072)
                     /locus_tag="NOA48_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCI0789194.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            37202..39109
                     /locus_tag="NOA48_000910"
     CDS             37202..39109
                     /locus_tag="NOA48_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCI0789195.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(39650..42928)
                     /locus_tag="NOA48_000911"
     CDS             complement(39650..42928)
                     /locus_tag="NOA48_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCI0789196.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        12162 a         9050 c         7674 g        14199 t
ORIGIN      
        1 atattgattt tttgtgcttt ttctttcatt tctccactat ctttttgaac gttctcccga
       61 acatctactg ttttgaatcc ttgactactt gtagaacttt gtacattttc tcgtacgtct
      121 actgttcgat ttccactttg actacttgta gtattttgca agttttctcg aacatctact
      181 gttctcggtt gacttgtccc actacttagt acattttctc gtacatttac tgttcggttt
      241 ccactttgac tacttgtagt attctgcaag ttttctcgaa catctaccgt tctcgattga
      301 tttgacgcac tactttgtac attttctcgt acatctacta ttcgatttcc actttgacta
      361 cttgtagtat tctgtaagtt ttctcgaaca tctactgagc gtctatcttg actacttgta
      421 gaattttgta gattttcttt gaccaatttt tctaatccgg tatttgaatt tttagcttct
      481 tgaattcttt ctttggtcaa cgcttctttt tcgtccatat tagcccctgt acgcccttct
      541 acacgtttcc tcaacatttc ctcacgattc attatttcag gcgtgtattt tgcttcctgt
      601 cgcttctgat taattaattc ttcagcagac ttagcttgac cgtgcatagc atttttacgt
      661 tcttcaatat cttgtttaac tttttgctga attgcacttg catgattagt atttgattca
      721 gcattatttt tcattgcttc acgcatacgt tcagaactag acataattct atcagcgttt
      781 tcaactttag cgccatcttt tctatccgaa agacgcgttg gcatagaatc agcatatttt
      841 ccagtttcat cttctttatt tttagctact ataggtttgc tatttttatt aatagcggac
      901 acggtaccat catctaaacc ttctttaaat ttattcttgg tatcattagc tatatcacgc
      961 atactcttaa atggttttgt tgctctttca ctagccattg tagctccatc cgaagctaag
     1021 cctgataatc cacgttcacg agcataccca agcgttttcc ccgttttatt agctttttga
     1081 gaaagtgatt gaccaaagtt gcgttcaggt tttcgttctt ccccttccgc ttgatcgttt
     1141 ccaccactat ttttcccacc tttagatcgg ttcataccac ctgttccttt acgaaacagc
     1201 atagctccca taccaaatgc tgaagcaagc tggccatagc cttcttttaa accaatatcc
     1261 acgccaaagt aacgcatgac tgttccacta ccctttatta gaacgaacac ggcacagata
     1321 taagcaattg tttttataaa aatattcgtt gagatacctt caccagcgtt tagataatta
     1381 acaaacattg caaacataga caatccgaat ccctgaaaac cgacagtcaa ataacactgt
     1441 agaatatctg acaaaacttg ttttgatcgt tgtcctgttt ctaagtcagt agcaaatacc
     1501 aaaactccaa gtacgcgttt aaatgctaac tcgagtattg ctgtaattat aatgaaagca
     1561 ctaaaaacat acgctactgc taaagcaatc aatccaaatg aaattcccca caagttcgct
     1621 tgatagcgat aatatcctga tttgatacca tcaacaaagg ttgacaaaaa attatctgaa
     1681 aatttagtag caacaaattc attatcagaa ttttcaacta attcataacg cagattatca
     1741 gctattgggt tctctttttc cattttgtcg agtacattat ctgtcaatac ttgcgtaaga
     1801 tccgttttcc aaaaattttc ttttgttaga ttgttccggt cattcgtttt atcgatcatg
     1861 gaatattgat ccgttttatt gatataagct aaatcagtaa ccccttgttc aatcagcgac
     1921 cacgccacgc cttcgtctga atctgtaatc gtagttgaat cattataaaa ggttttagaa
     1981 aactctattc cgctgtgaat caaagttggc attaaaagaa tcaatgaaat tgacattaca
     2041 acattcattc caacagattt tagatcaacc gttcctttac ctataatcat tttataacca
     2101 acaatcacta gtgaaagtat cattaagcca acaacaatgg tacttaaaac tgattgatag
     2161 actttgttca atccagcact ttccacaaag ctaaacaaat ctaaaacctc gggaatcata
     2221 ttttgaatgc catcgacaac agcgaacatt gattttataa cagaccagcc tatccacata
     2281 ccgaactgac tgtaaaaatt tccgttatat tttttaagat aattctgata aagtggatta
     2341 gttaaaaact cagtttggct ttttgtatca tcaaaccagt tgaaaatact gccttctgca
     2401 acgttactcg taaaaataat catagctatg agaataagaa aactaatcaa caaccaattt
     2461 atttttctat tggcaatctt ttttccaata attttcattg ttacctccct cagcccagtt
     2521 tctgaggctc tcagagagct tttgagcaat tttttggtca atgatgatat gagttacata
     2581 actatcattc actgctctta aatcgagaac aatagtgttg aagcagatac actcgattaa
     2641 ttcaagtgta tctgcgtttt ggtcaagaca gcagatttga tctattagac gatttccaat
     2701 catattaaga gtcctttctt gtttatttac ttagagcatc tatgatatac attctgttat
     2761 cttgttcttc taaagcaatt tctttccagt gatttcgaga taccgtgttt acatacttca
     2821 tttcattcaa ttctttaccc aagtttaatt tctcgttaat cgtattaaat aatctgatta
     2881 tcatcttatt tgtttgttca tagtaatgtg gcccatcgat tcgaattttg aactctcttt
     2941 ctgttgaatt tttcatatct actattaatt gaacgaattt ttctctttga cttttagtaa
     3001 atctgtcacc tagtttatga atcagctgta ttcctttctc gttaattatc tcttcattga
     3061 taatagtatc aacttgatta atcttatcta tactattctt aactaaacta gatttatctg
     3121 aactaatctg atcttgactt gactgaacct ccaaatggtt gatgctaggt ataccaactg
     3181 gataccattt ttccattaaa tcgactctta gcggttctac ttggccagat ttcaaaatca
     3241 catcaagttt tattggcttt aattttgaga aaaattctgg ttttaagttc aataacttga
     3301 agcgataaat agatggttta tacctatcta ttcgtatatt ttggttttgt aaccaatgcg
     3361 gtaggaatgc taacaaatct tcatttaaaa aaaatacaaa accttttgta aaaagtatct
     3421 ttacatcatc gtcaggagtc ccgagcattt tcacgtatgg atatgcttca acaattccgt
     3481 catcgtctgc atttgtgttc agatatacat ataataattt tgctgaatct gacatcttca
     3541 taaaacttgc attatttaaa aatgttttgg acagcattcg tttttctgcc atggatttca
     3601 cacttctttc tatttgaatg gtaaaataaa ttcaaataaa gttttatcag aactttattg
     3661 ttgggtgttt cccttcgtct acaaactatc gggagcactc ttttatatat ttttttcaat
     3721 tcttttcaag tctaaatttg ttatttcatt ttctctcaaa actttcacct cttttcattc
     3781 gagcaaacat aaactcatta actgcctttt tcgaataaaa ttttcttgcc cctaattcaa
     3841 caacgggcaa tccctcattt ctcaccgcat tttttaaaaa gttttcgctc acatttaagt
     3901 attctgccat ttctttttga tttagatatt ctctagtcat acccgcattt tcttgagcct
     3961 tctcaatcgc ttttgtagca atttgataaa actgctttag aaacatttcc tcctgttctt
     4021 ctgaaatcat taattttatt gcttccacaa aaacctctcc tttttaatta attattctat
     4081 aactcctcta cctttataag tacaaataaa tacaaattgc gtaaaaaaat gtatttattt
     4141 gtatttataa gaataaagta tcatactcca gataaaaagt aaatactttt aaatactttt
     4201 gttttataaa tatgatatac tatctttaaa aataaaaagg agaaaaaaga tgaagccaaa
     4261 tccttcagaa gcaggaaaac gaatcaaaca attacgcctt tcatgtggtt ttactatgga
     4321 agaacttgga aggaaaatag ataattcacc acgtgcgacc atatccaact gggaacgtgg
     4381 gaccaattta ccaaatccac aaaagctgaa attattatca actatcacta attcaacaat
     4441 tgactggatt aaatggggaa ctttagaaga atatataact tcatacctta tcgatatagg
     4501 gtatgagcta tatattaagg actttccaga aatacctcac aaagtcttta aagacattca
     4561 agaaagatat agtgatacgt tttcgctaga taaagactat gagttattga atcctataat
     4621 aaaaaatata tttacaaaat attactcaaa agattttgaa atttatctaa atgagatact
     4681 tgctaataat atcaatcctc tgattgaaga gtacgctaac caaagacact ctatctctaa
     4741 agagctattt ttcaaaagag ccaacagtaa acttcaagac aagataagaa atggtgattt
     4801 caaatacggt gaaaaagaaa gaatgattga ttctttaaaa cagctattag acgaaatgga
     4861 cttagcctat aaagatattt caaagtattc atctgtcgag gatttctttt ataaaattac
     4921 taaaaaccaa tttgaaacag aaaaatttat ttcagatctt agtaaaaaat acaatttccc
     4981 atatgagaaa aatagtataa tcgcaaaatt tttaactgat aatcacgata aatttaaaaa
     5041 taattgattc ttcaaataac ttctctacct gcaataatga agtaaggaga gaatcaaatg
     5101 gcaacatttt ttagttataa attacaaaat ggcgaaaaat attggggatt tgaaacttat
     5161 ttagggaaag atcccaagac tggaaaagat atacgtacaa agcgtagaag attcaaatca
     5221 aaagctgagg cgcaaacagc acttaataga ctacttgtag actttaaaga aaaacaagag
     5281 tttaaaatca atgttacaac ttttcaagag ttgtatgaat tatggattga taactacaga
     5341 acaagagtaa aaccgtcttc tgttgccgtt gctcaacgtt tttgcaaaaa ccatatatta
     5401 cctgcttttg gggaattacg attggataaa ataagtgtta gctattgcca aaaacaggtg
     5461 aatgaatggc acaaaacatt aaaacaatat ggtttcttga gaaaaacaac tgctcaaatt
     5521 tttaaatttg gagtagcaat ggaagtctgt aaggataatc ctatgtctaa aacattgctt
     5581 ccaagaaaaa ttgaagaaga acaacccttg aagttttaca cgaaagatca attacaactg
     5641 tttttacaga atactaaaga aaattattca gttaaaatgt acactttttt ccgtttatta
     5701 gcttatacag gaatgcgtaa aagcgaggca ttggcgcttc aatgggaaga tatagactat
     5761 ttcaacaaaa caataacaat tggtaaaact atcgctcaag acgagtttaa tcaagtagtt
     5821 ttacaagtac ctaaaactaa aaattcatca agaacgattc agcttgatga ttttacactt
     5881 aaacaactgc gtatttggca acaagaacaa atgaaaataa tgatcttata tggctataac
     5941 acgaattcac caaaacagtt tcttttcact acaaacacaa acaagttgta ctacccccaa
     6001 gtagtaaacg attggttaga ctggatttac aaaaagacac cgatggagcc tcaaattact
     6061 ccacatggat ttaggcatac ccactgtagc ttattgtttg aaagtggtgc gtcgataaaa
     6121 gaagtacagg aacgattagg tcataaagat attaaaacta ccatgaatat ctatgctcat
     6181 gtcacaccac aatctgttaa gaaaactggt gaccgatttg caaaatttat gggcgaataa
     6241 ttccaaacgt agccaaaaac gtagccaacc attaaaatac aaataaaaaa acgctcgaaa
     6301 cgctttaata tcaacgtttc gagcaatgaa atagttgtta acccacagac ccttccatct
     6361 cataactgat caatcgattg agttcgactg catattccat tggaagttct ttggtgaatg
     6421 gttcaacaaa gcccatgacg atcatttcag ttgcttcaga ttcggtcagg cctcggctca
     6481 tcagatagta gagttgttct tctgagattt ttgagacttt ggcttcgtgt tctaaagaga
     6541 cttggctgtt gtggatctca ttgaatggga tcgtatcgga tttcgaccat tcgtccatga
     6601 tgatcgtgtc acattcgata tgagagatcg aacccgcact gtttttggca aaggttactt
     6661 gtcctcgata gtttacttct ccgccgtctt ttgaaattga tttagagacg atagagctag
     6721 atgtatttgg tgcattgtgg atcatttttg cacccgtatc ttggatttgg tttgctcctg
     6781 caaaggcgat ggagagcatg gtgcctcgtg caccttttcc atctaagtaa acacttgggt
     6841 atttcatcgt tgtttttgca cctaggtttc cgtcgatcca ttcaacggtt gcgccttcgt
     6901 atgcttttgc tcgtttggtt actaagttgt acacattgtc tgaccagttt tggatcgttg
     6961 tgtaacggca atacgcatct tttcttgtaa agatttctac gatggcggca tgcaggctgt
     7021 tacttgaata agtaggtgcc gtacaacctt cgacatagtg gatgcttgct ccttcgtcaa
     7081 caatgatcag cgtacgttcg aattgccccg tgttttccgc attgatccgg aagtacgttt
     7141 gtaatggaac atcgactttg acgccttttg gcacgtaaat aaaggtccca cctgaccata
     7201 cggctgaatt cagcgctgct aatttgttgt cggttggcgg tacaagtttt gaaaagtact
     7261 ctttgaataa ttcagggtat tctttcaaag cagagtcagt gtcagtaaag acgattccta
     7321 acttttcgaa ttcatctttc atattatggt acacgacttc tgattcatat tgtgcggaag
     7381 caccggctag ataagctcgt tcagcttctg gtataccaat cttttcaaat gtatctttga
     7441 ttttttctgg tacgtcttcc cagtcacgag cgggtttgtc acttggtttt tggtaatatt
     7501 tgatggcatc gaaatcgatg tctgaaaggt cggggcccca tgtttgcatt ggcattttgt
     7561 taaatgtttc tagagatttc agacggaatt caagcatcca ttctggttcg cctttgattc
     7621 ttgacatctc acggatcact tcttctgtca agccttctcc tgtactgaaa accggttcga
     7681 catcatcgtg aaacccgaat ttatattctt ctaattctgg tacgcccatg ttctcactcc
     7741 tcttccttgt ggtaatgatg gaaagctgcg gtaccatcgt tttccattgc ttttcctagt
     7801 gctttccagg caagtgtcgc acatttgatc cgagcgggaa atttagctac accaccaagc
     7861 atagcagcat cgcctaattg gtcgggatct ttgacttctt ttccttggac aagctgtaga
     7921 aagtctacag ttaaatgttc tgcttcttct attgattttc cgatgacggc gtctgtcatc
     7981 atcgaggcac ttgccgtact gatggagcag ccactgccgt caaaggcgat atttttgatg
     8041 attccgtctt ttacatcgac ttgcaattcg atcacatctc cacatgtggg gttgttcaat
     8101 tcgatcttgc ttgtcgagtc agtcaagctt ccacgatgat gcggatggga agaatgatcc
     8161 aagatcactt gacggtataa attgtctaat ttagatagtc ccatgttgga aaaactcctt
     8221 tgttgccatg attgcttcaa ctaaacggtc ggcgtcttgc gttgtgttgt agaaataaaa
     8281 gctcgcgcga gcagtcgctg atacttcaag gtacttcaat agcggttgcg cacaatgatg
     8341 acctgctctg acggctaccc cttccatgtc taaagctgtc gcgacatcat ggggatgtaa
     8401 cccatccaaa ttgaatgcaa cgactcctgt ccgaaaattc gggtcttgtg gaccataaac
     8461 agtcaatcca tcaattgctt gtaattttgg caacacataa gcggctagtt cttcttcata
     8521 tcgatggata ttgtccatac cgagtttttg caaataatcg attgcatggc ctaatgcgat
     8581 agcgccggcg atatttggtg tccctgcttc gaatttccaa ggtagttctt tccatgtact
     8641 gtcgtataat tcgacaaaat cgatcatttc gccaccaaat tcaacaggtt ccatttcttc
     8701 taaccatttt cgtttaccat ataaaacacc aatacctgtt ggtccgcaca ttttgtgtcc
     8761 gctgaaagca aagaaatcac agtctagtgc ttggacatca atggccatgt gcggggcaga
     8821 ttgagcacca tctactacga tgaccccgcc gttttcatgg acaagttcag ctaattcttg
     8881 aacaggattg aagacaccta agacattgga tacatgagca atggagacga ttttggtttt
     8941 gtccgtaatc tttttcgctg catcctccat atccaggaag ccttcttctg ttagttcgat
     9001 atatttcaag acagcacctg ttcgttttgc caactgctgc cacgggataa cattagaatg
     9061 atgttccatg taagagagca ctatctcgtc tcctgctttg atatagcggt cgccgaaggt
     9121 tctggctacc caattcaagc ttgtcgtcgt accacgagta aacagcactt ctgctgtttc
     9181 ttttgcatgg atgaacgccc gtactttttc tcttgcttgt tcataatcat gggtcgcgcg
     9241 ttctgctaac gtatggacac cgcgatgaac attggcgtta tcgtgttcgt aatagtacgc
     9301 taatgcctgg agtacttgtt ttggcttttg ggtcgtcgct gcattatcca gataaactaa
     9361 aggttcatca ttgacgtctt gaaataagat aggaaaatca ttgcgtagct ttttagcatc
     9421 gatcatccat tcaacttccc ttcgattact tcgactaatt ctttccgaac ttgttctaca
     9481 gggattgctg ttaagacaga accgaggaat cctcgaatca ctaagcgctc tgcttcttct
     9541 ttatgcaatc ctctactcat cagatagtac atttcttctg gatcaactcg tcctacactg
     9601 gcagcatgtc cagcagttac ttcgttttca tcgatcaaaa gaataggatt cgcatcacca
     9661 cgtgctttat cagaaagcat caagacacga ctttcttgtt gggcatctgc accttttgcc
     9721 cctttcaaga tgtggccgat accattaaag gtcaatgttc ctttttctcg gatcactccg
     9781 tgttgcaaaa tatgcccgat cgtatgaggg gctttattgg ttactcgtgt atcgattcct
     9841 tggatttgtc tgcccgagct gattgccacg attttgactt ctgcgtgtgc accttctcct
     9901 gctaaatctg agtcaaagtc agcgatcaca tgaccgtcat tcatgacacc aattgcccag
     9961 tcgacagaag catctcgtaa aatgtgccca cggcgattca tataagaagt aatattttct
    10021 cctaattgat ctacggctga atatttgatt tttgaaccag ctttagcgat gacttccacg
    10081 atgatattac ctgatgattt tgctacttgt tctttggttg tctggaaacg ttccagataa
    10141 gaaaattcac tatgttcatc tgccacgatc aacacatgct tgaagaagtg ctcatcggat
    10201 gcgccatctt gaatgaataa ggactcgagt ggttcatcga tcacgacatt tttaggcaca
    10261 tacaggaaaa taccgctgtt cataaaagct acatggagtg cagtcaattg gtcttcgttc
    10321 atgtttactg cttttttcat ataatattct tggactagtt ctggatattc gatcattgca
    10381 gtgaacaagt cggtaaaaat gactcctttt tctgctaatt ccacaggcag ttgttcaaaa
    10441 atcgtccatg aaccttgttg gacaagcaca ggattgtctt tcattgcatc aaatgccgga
    10501 atcgtgcctg tttcactgat ggtttgtgtt tctttcacat caaataacga ccagcgatgg
    10561 aatttcaccc gatcgatatg cggcaatggc agttcatctg ctttcgctag tgcgtcttga
    10621 cggaaggttc tcatccaatc aggttcgcct ttacttaaag aaaaatcatt taccgcgtca
    10681 agataatcga gccagttttt ttctttcatt cttgctcccc cttacgcttc ttcttcttta
    10741 tagtcgattc ctaattcttt actgatacca gcgtagcctt ctgcttccag acgtttagct
    10801 aggtcagcat tccctgtcat gactactcgg ccttccatca tgatgtgaac gacatcaggt
    10861 gtgatatagt tcaataatcg ttgatagtgg gtgatgatca atgcaccgaa attgtctccg
    10921 cgcatttcat ttactccttt agcaacgact ttcaaagcat cgatatccag acctgaatcg
    10981 atttcgtcta aaattgcaaa tgtaggttct aacatcaaca attgcaggat ctcattccgt
    11041 ttcttttctc cgccagaaaa accttcgttc agataacgtt cagccatttc ttctggcata
    11101 tttagtaaag ccattttttc atctaacttt ttcaaaaatg ccataacaga aattttgtcg
    11161 ttttcatcac gtttcgcatt gatcgctgca cgcatgaatt ccgcattcgt gatacctggt
    11221 atctcacttg gatattgcat agctaaaaat aagccaagtc gcgcacgttc atctacttcc
    11281 aagtctaaaa catttttccc gtcaaacaaa atttcgcctt ctgttacttc atagtttgga
    11341 ttgcccatga tagcggcaga taaggtagat tttcctgtgc cgttaggtcc catgatggca
    11401 tggatttctc cggttttcat tgttaggttt acgcctttaa ggatttcttt ttcctcgatc
    11461 gacacatgta gattttttat ttctaagaca gacatgcatt atacccccaa attctctttc
    11521 gttctcactc attttagact aattgagaat gaagcgcaat gaccttcctt actaaaatca
    11581 aatatctttt atttattatt aaacaatttt gatttctaaa ttagaatagg tataaaaaag
    11641 atgagaaata agccattaca gacttatttc tcatcttttt tgttccatac cttattttgc
    11701 atcagccttt actggtttaa cagagccgcc ccatttgtct gtgatccatt cttggacttc
    11761 tttgcggtga agcacttcaa tcagtttttt gattttgtca ctgtcttcat cacctttacg
    11821 agtcgcaata atattcacgt aaggagagtt gtccttttca agcaatacgg catcttctaa
    11881 tggattcaac cctgcgccgt aagcgaagtt tgcgttgatt gcaactaggt caccttcatc
    11941 attttggtac gtagaagcta aaagtgatgg gtcgatcgta tggttgaact tcaagttctt
    12001 agggttttct tcaatatcat cgaatgttgc tgtttccaga tctactccat ctttgacttt
    12061 gactaagcca gcatcttgta gaattgtgat gatgcgtccc cagtctgatt cagaatttga
    12121 agtaatgatt gttgcaccat cttttaattc ggaaacatct ttgacttttt tagagtacaa
    12181 gcccattggt tcgatgtgga cagcaccggc attgacaaag tcatatcctt tttctttgat
    12241 ttctttgttc aaataaggaa tatgctggaa gtaattggca tcaatgtcgc cttcttccaa
    12301 agattggttc ggtaatacat agtcatcgaa tttgacgatt tcaagatcga ttccttcatc
    12361 tttcaataat ggtttcacat gttccaaaat ctctgcgtgc ggtgtcggtg aagcgccgac
    12421 tttcaatgtc gtgtcgtctg ctttatttgc tgaatctttg ctgtcgctgt tgttaccgca
    12481 tgctgctaat cctacagtca gcaaaagcgc tgctgcaaat ccaaaaattt tctttttcat
    12541 atcctacatc cccctatatc ctattatctt ttgtctgttt tcttagttaa gaaatcaccg
    12601 attccttgaa cgataaatac gattagtaaa ataattaaag tcgcaacgaa tgtcactgtt
    12661 agattaccac gctggtagcc ttcctgccaa gcaagacctc caagtccacc tgcgccgatc
    12721 gcgccggcca tcgcagtaaa tccgatcatc gagatcgttg taactgttaa tccagaaatc
    12781 aatgcgggaa tactttcagg tatcaagacc ttccagatga tttcccagta acttgctccc
    12841 attgcatctg ctgcttccag tacaccaggg ctgacttcac gaaaagcaat ctctactaga
    12901 cgggcataaa atggtgctgc ggataaaaca agagctggaa tggctgcttg cgcacctagc
    12961 atagtgccta cgattgcttt agtaaatgga atgatcaaaa ccatcaggat cataaatggc
    13021 gttgaccgga aaatattact gatgatcgat acgattccat aaatgattcg agcatacggt
    13081 ttgtttttgc gtccaataga gtaaaggatc aatcccaaaa ctaatccgat gatcgtcact
    13141 aagaccattg agattaatgt catatatagt gtatcaagga tagcctgatt catcgtttcc
    13201 gggttgattt gtttaaaatc tagatatgtt tctgaaaagc ttttatccac gatggatcac
    13261 ctcaattcct actccttgtt ctttgatgaa cacttctgct tgatctaatt ctttggtttc
    13321 accagtcatc aagacagtca atgaaccaaa ggaaccttct ttcacttgtt tgatctttcc
    13381 atacacaacg ttgacatcga tgttatagcg tcgaatcgct tgggaaatga ctggctcgtt
    13441 ggcatttctt tcgctaaagg tcaaagttgc caaacggccg cttggatttt ctttgatgag
    13501 ttcagctaat agttctgtcg aatcagcttc tggttcgatg tcttgttgta caaagcgttt
    13561 ggttacttct tttttcggtt gtctgaagac agtcaatacg tctccttctt ctacgacttt
    13621 ccccaactcc atcacagcga ctttgttgca gattttgcgg atcacattca tttcatgtgt
    13681 gatcaagacg atggtcaaat tcaatttctt attgatcgct aacaataagt ctaatacttc
    13741 ttctgttgtt tgcgggtcca atgcgctagt agcctcatca caaagcagga tctcaggatc
    13801 atttgccaat gctcgtgcga taccgacgcg ttgtttctgt ccgccggaaa gttgtgaagg
    13861 atatgcttgt ccgcgtcctt ctaacccgac taaacgcaac agttcttctg cccgttcttt
    13921 acgtttgctc tttggtacgc cagctaattc cagcggcagc tggatatttt caagtacagt
    13981 tcttgaccat aacaggttga aatgctggaa gatcataccg attttctttc ggaatgtacg
    14041 taattctttg ttttttaatt ttgtaatatc ttgatcgttt acgatcactt cgccgctcgt
    14101 gggaagctca agtccattca ggagacggac taatgtactt tttcctgcgc cagaatagcc
    14161 gacgattcca taaatatccc ctttttcaac gtttagtgaa acgtcattga cggcttggat
    14221 gtttccgttt ttcccattga atgtcttttt gacattcgtt agttggatta atgacatgcc
    14281 attcacatct ttctcttata atttttcaaa caaaaaagcc ttcgccctct tgccttaagc
    14341 aaaaggacga aagcttgaac ttccgtgtta ccaccttgat ttaccgttac ttcgcaataa
    14401 cagcctcttc cagtacttgg acttagcttc tttccgtata ctgtcgcgct gtaacgggca
    14461 ctcccgtagt aagtttgctt acgctcgctt actctgctct aagaccatct tccatctcat
    14521 tttcgttacc cattttcagc aaacagggct ctcttcaaac gtccgtgaca tgtactcttc
    14581 ttttcaaagc tttctcgttt catataggat tgcttatgat tatagcaact ggaagaatca
    14641 gtgtcaactt ttttcaagtg attttctgat tttataattc gtcaaattct tttggatcaa
    14701 catctttgaa acttaagatc cacgcattca tttcatctga atcattcaag atattgatat
    14761 cttcaccgat tttatcatta acagaagaaa ctgtacccgt tagcgggctg gcaaattcat
    14821 tgaccgcttt ttccgcttca acttcgatca gaggttcatc tttttttagc gattgtcctg
    14881 cttttggcag attggcaaac gtgatgtctc caagttcttc ttgcgcttca tttgtcaaac
    14941 caacacagta ttcttttcca ttaaataaga tccaaaggtt gtcctttttc ttcaaatgct
    15001 tgcctgccat tttatatcag ttctccttca taaatttttt cattgaatcc aattgcaaca
    15061 agctggtcct ctcgtaagat cagtggtcgc ttgatcagca taccatctgt cgataagact
    15121 tggctcgctt ttgaagccgt aaactcgcct acttgatctt tcagtccaag ttcccgatat
    15181 ttcatcccgc ttgtgttgaa caggcgacgg attggtactt gactcgtttc tagccaagtc
    15241 tcaatcgttg aggccttcgg tacttctttg atcatatcaa cggtttgata actaacgcca
    15301 tgctggtcta accacgcttt ggcttttttg catgttgaac atttcgggta ccagtaaaag
    15361 gtgtacaatt ttcttacctc cttgaagatc ttgcaggtgc ttcattttgg tatctcatcg
    15421 ataatatcaa cccgataccg atcatgttcc ctaaaatcga ggatcctccc tgactaatga
    15481 aaggcaatgg gatccctgtt aaaggaagta atccgatatt tgctccaata ttctcaaaga
    15541 catggaacag cagcatcatg atcaaaccgc ttgcgatata ggcgtaaaat tcattattcg
    15601 tatcgaaaca cacccgaatc atacgataga ttaaaataaa atacaagaaa atgacgaatg
    15661 caccaccgat aaagccgaag ttttcaccga taacggtaaa aatcatatcg gactcacgaa
    15721 caggcacata gatattgctt acgttgaatc ctttaccaaa caagccaccg gtaccaattg
    15781 ccaaaagtcc ttgggccggc tgataactca ttcctgacgt atcatggaaa gggtccagcc
    15841 atgaatcaat acgtgcaaac tgataagatt tgaatccaac tttataaagc aagtctcttc
    15901 cgccttcagt cgtaaccaag aagatcgttc ctgctccaac gactactgcc aagattacta
    15961 caggtgcgat gatgcgccaa gagattccag acatcaggaa aatcccgcca aagatcgcaa
    16021 gaaagacaag catcgttcca aagtcatctt gggccatgat caatgctaaa accggtattg
    16081 tcacgatcaa gagcttccca atcagccaaa agtccgattt catcgtccgt tcttttactt
    16141 gcgtattatg tttagttacg atcagtgcca tcatcaagat gtacgcaatc ttcatcaact
    16201 ctgctggctg gaaagtaaac gcaccgaatc gaaaccagtt tttagaccct gttgaagcag
    16261 ctaaattctg atcatagaat ttgagcaaga gtcccattac cactaacccc aaaccataaa
    16321 ggtaaggagt cagtttccag atccatttgg aattcaaatg catgatgaca acgattgctg
    16381 ccgctccaac taaataccag acaacttgca tccctacgcc tttcaagact gctggattgt
    16441 tcggatcatg gctaagtgct acatataatg agagcagacc aatcaaacat aacagaaaga
    16501 ctggtaaaat cacgccataa tcaatacgat tatcgttcga agcttttaat tttttttcca
    16561 tgtttcatcc cttttcttaa aaaccatact gctgattatt atagcggtcc agttagataa
    16621 tggaaagtct ttccatagac atttgggaaa aattaacttt ccgtttgtgc agttgcttga
    16681 gcaaatgcag tacaaaagcc tactgcttat ctttagtgta tcatagaact ttttttgata
    16741 catgcaatta tctaccagct gagattctcc tcgctgtgag aagtttctgt gctttcattg
    16801 tatcgaagga tctcttcggc aatctctagc agctgatcag aaaccagatt ggttcgttgg
    16861 atgaaataaa aatatcgatg gaaattcaac ggagtcattg gcacattttc tggaacagag
    16921 cgcttagaca aaatcgagcg accgattcct tccttcagca acgcaacaat tacatcgtta
    16981 cttttcacga tcatcttctt atcttggata ttcatctctt caaaataacg ctgcgtgtaa
    17041 tgaaaaacac cagagtttgc ttctcttaca agccacaatt tgctttttgg gtccccagcg
    17101 atgactagct ggtcttccat caaagagtat ctttgtacgc cggaagtctc taatggcttt
    17161 tcgataaaac caaaatcgga ttcatgtttc gctacttgtt ctaatgattc atgagaattc
    17221 gtgatttcga tctcaaaatg cactttagga aaccttttga tcagatgttt catcaactga
    17281 ggcaaaagat agacagcaaa ggtgtgggaa gcaacgatcc gacatacttc ttcttcattt
    17341 tgttcattga gcaatttttg ctgagtttct tcccattctt ctaacaaaac cagtgtccgt
    17401 tcatataata agtcggcttg cttagttgga agcatctctt ttcttccgtt acgttgaaaa
    17461 agatcgatat tcaattcccg ctccaactgt ttgatttgat tcgagactgc tggttgagat
    17521 aaaaacagta cttctgctgc tctggaaaaa tttcttgttt catatactgc tcgaaaagtc
    17581 gttaataact taaacatggc accacttcca taacttttta tgataattac tataaaaact
    17641 atttgattta aatatacaaa aaaccatcta taatagaaat gtacaacaaa acagttgctg
    17701 atccaactag taacttagat gaagacaatc agctgtctgc ttgctcgtaa tcatacattc
    17761 ctattcattt tacaatgtat tcgttcatct tggtactaaa atctattaaa taaaaaggag
    17821 aatattatat atgaagaact ttttgaaaat tattccgatc ccgatctgcg ggttgatcct
    17881 tgggttagct tcccttggaa atctgtttaa agactatcac catgttgctt taggcaatct
    17941 aactggcggt atctctatga ttcttatgat attcattttt gttaaattgt ttatcttatt
    18001 cgaacacacg aaacaaacgt tgcatgatcc aatcatcgcc tccgtttcac caacttttac
    18061 gatgtcactc atggttattt gtacttattt tgtttcatat gaaagtattg caccaattgt
    18121 caaattcatt tggctgtgcg ctgttatctt ccaagtgatc cttgtctttt atttcaatta
    18181 tcaccatgtt atcaaagctg atctttcaat tgaagcaatt tatccaagct ggtttatcat
    18241 ttacgttgga tttggggtca tcactgtaac tgccgggaac ttcttcccac ttattggaaa
    18301 aattttcttt tggatttcat tgatctgcta tgcgttctta ttgccgatca tcatcaaacg
    18361 tgtctttttc gtaagaaata tggctcatcc gacacgtccg ctgattacga tcgttgcagc
    18421 acctggttct ctttgcctaa caggttatct taaaaacttt gctgaaccta atttttatct
    18481 tgtcgtagca ttgttcgctt tatctcaagt attgtatttc gttgtgctgt ctatgcttcc
    18541 acgtttgttc aagcttcgtt tttatccaag ctatgcagcc tttacattcc cgcttgttat
    18601 ctctgcaaca gctatattta ctactgttca ttacttcaac agtttaggta tctatagtag
    18661 cgtattggat ttcttaaaag ttgcggaatg tctgtttgca agtgtagttg tcttctacgt
    18721 tcttgctcat tacgtacgtt tcttaattaa agaacatagc aaacatggaa aatttgtttc
    18781 taaaaaaatc gcttaataat cgattcaata ggttgtgaaa aagctgttct gcatcaagta
    18841 ataagaacgg ccaaacaaaa acagctgttc atgtttttgt actggttggg cttattaccg
    18901 cagatgcaag cttttgaaca ccgtttacca agaggtcgta aaagaagtgg tcagcttcaa
    18961 gaaataagaa ggaatttacg aaaattgctt ctcaaatttt tgtgaaattt cggcttattt
    19021 ccgtagaagc tacttctgga acaccgttta ttcgaaacaa gaggtcgtac aagacttttg
    19081 tcacgacctc ttgttctttt gtcaaaatac tggtttagtg ctactatgtt cgagtatgct
    19141 tttagtattt attgacgaaa ggaaccgatc aaatgaaatc attgtcacat ccaataaaat
    19201 ctgtaaagga ttcagcggtc cgcgaaatct tacccggttt actgctttct tttgccatcg
    19261 ctgccttcag caggcttctt gctatttatc tgccacagtt aggtggagcg actattgcta
    19321 ttttattggg tattttatta ggaaatactt tttttaaaca gcctgttcta gcaatcggca
    19381 caaaatttgc tgaaagcaaa ctattagaat tctctgtttt tttactaggt gcaactgtca
    19441 cagctcaaac gattgctcaa attggtgtaa aaggaattgt ttttgtgtta ctgcaaatgt
    19501 cagtcactat catcggtgct tacttgattg gtaaaaaact gcaattcagc gatacttctt
    19561 ctttgatgat ggctggagga aacgctgttt gtggttcttc tgctattgct tcaatcgccc
    19621 cttccatcca tgcgaaagag gaagaaaaag gacagatcat cacactagtc aatctactgg
    19681 gtactgtgat gatgttgact ctcccttttc ttggattaca gttgtttggt ggaaatctca
    19741 ttgaaaaaag tgcacttttg ggtggtacac tccaatctgt tggtcaagta gtcgctgggg
    19801 caagcttact tgacaattct gttgtcgaat tcgccatgct atttaagatt ctacgtatta
    19861 tgatgctcgt tgttgttgtc tatctgtttg aaaaattcat gcacaagaaa caaccagctc
    19921 tgtttgaaac gccaactgat acgcagaaaa aacgaaaatt accgcttcct tggtatgtat
    19981 tagggtttgt gatcttttgt ttggtcaaca gcttgttttc tttacctgta gttattgacc
    20041 aatcggcaca ttttatcagc agctggtttg agatcactgc tttagcggca attggtctgc
    20101 gtttagactt tgcaaaattc atgaaagaag gtacacgctt cttatcttat ggattagctg
    20161 tcgggcttct ccaaacagtg atggctttac tatttatttg gctgatcaaa gtttagaatg
    20221 aacatgaaaa aacagttgtg attctcgcat ggaacaatgt ccgaatcaca actgttttta
    20281 attttgcaga tatccttcta acaacaacaa ttggcgtttg atttcaaccc catctattgc
    20341 gtttcccata tatcctgtca gttttccatt ttgcccgatc actcgatgac aaggaataac
    20401 gattggcaat ggattggttc gatttgcctg cccaatcgct cgcacagctt tcggactatc
    20461 aacagcaacg gctacttctt tatacgttcg gatttctcca taaggaatgg tcgacaaagc
    20521 tttccagaca ttttgctgaa aaggcgtacc tctctttata gataaaggaa catcaaattc
    20581 ttttcttttt cccgcaaaat attcttcaaa ctgttcttgt gtgcgcgtta aaattcgctg
    20641 attcgctgat tcgctttctg aaattggctg aaaagataca gcagtcaatc cggattcatc
    20701 tgcatctaac cataaaaagc cgataggtgt gtgtattttc attttgtttg ctcctagtca
    20761 atagactgga acttcctcct ttttctctat ccaaaactac ttgccaacta ataaaaattg
    20821 ttcttaaaag tttgataaac cgaggaaaca tggtaaacta aatacgttag tttacaaaaa
    20881 gaatacctgt tcttttacgt aaaatcaaat tttaaaggtg ttatttaagg tttattaaat
    20941 tttgaatgta aaccatatat aaacatacga ttgaaaggat agaaacgatg aaagtatcaa
    21001 ttgttgtccc atgttttaat gaagaaaaaa ctgttcctct tttttttgat gaggttgaaa
    21061 aattcaaagg tgcccatgag ttcgaatatt tgtttattga cgacggatca aaagacggta
    21121 cgttagcagc aatcaagaag ctagcctcag cttatcctta tgtccgcttt gtctcatttt
    21181 ccagaaattt tgggaaagaa gcggctctgt acgctggatt gcaagcttct acaggagatt
    21241 tagtgaccgt gatggatgtt gatctgcaag atccgcccga actgcttcct gagatgatca
    21301 accggatcac tacttctgat atcgattgtg tcggcacccg gcgttcgact cgtgaaggcg
    21361 agcctgcgat acgcagtttc tttgcgaaaa aattctacca gttgatcaat aaaatcagcg
    21421 atacagaaat ggtcgatggc gctcgtgatt tccgcttgat gactcgtcaa atggtggatg
    21481 ccgtcctaga attaacagaa tacaaccgat tttcaaaagg attatttagc tgggtcggat
    21541 ttaaaacaga atatatttct tatgaaaacc gcgaacgtgt ggctggcgaa acatcttggt
    21601 ccttctggaa attattcaac tactcgattg atggtatcgt gaacttctcg gatgcaccgt
    21661 taacgattgc ttcatttatc ggcgctttgt cttgtgtcgg ttctggtatt gcaattttgt
    21721 tcattatttt gcgggcattg ttgtttggtg atcctacatc aggatggcct tccatggtct
    21781 cgatcttcct gttcattggt ggaatccaat tgttatgtct tggaatcatc gggaaatata
    21841 ttgggaaaat cttcttagaa acgaaacagc gtcctgttta tatcataaga gaaacagaaa
    21901 aagtgaagcc aaatgaattg aagcctcacc aataatatac gtcaaatgaa gtaaacattt
    21961 ttttaaatga aaaaggactg tgacaaaagt cttgtcacag tccttttttc cgaataaatg
    22021 gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt tgagaagcaa
    22081 ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctatcacaac ctctttcata
    22141 tcttattact tcttcattgc tgcttttagt gctgctgcta atgggctttc ttctggttct
    22201 tctgcttgtg catatttttt cagcaagcgt cgttcttcat gtttggtcat tttcttcttc
    22261 tgctcttttt tatcaagcaa tttttctgtc gttccatcgt atttacaacg gaaataagca
    22321 ccgtttttac cttcgatgat ttccattttc cggtgacatt gcgggcatcg atgattagag
    22381 acttttggat cttttcttct gcggtagttg caatctgaat tggtgcagac atagattttg
    22441 ccgtcacgtg tgtttttctc gcgcagattg gccccacatt ctgggcattt cttttgggta
    22501 atcgagaaat cttgatattc ttgtttgctt gatttgatct cattcaccaa gcgttttgtt
    22561 tctttttcga ttccattcaa gaaggttcct gcttgtttct ttcctgcagc aatagcttca
    22621 aggtcttttt cccagctttc tgtcaaatct ggtgttacta aagagggatt taccaatact
    22681 aataattgct tacctttagg agatacttgc agtccttgag gggtacgttc catcagttca
    22741 gatttgatta gtttctcgat aatctctgca cgcgtagctg gggttcccag actgtatttt
    22801 tccatttgac caagcaagct tgcttctgac aatggtttag gcggtgcaga tagttctttt
    22861 ttgatggcga aatcgggatt gattctcatt cctttttccc atttgactgt ttccgtctca
    22921 gtttcagttt cgcctttcca tcctgcttgg acgacacgat tttgccgaaa aatgaatcgt
    22981 tctttaccaa attcaaccgt aacttttgtt tggctgactt tatggggttg agcaaacagt
    23041 cctaaaaaac gagagacaat catttgatag atttttcgct cttcattact taatttttca
    23101 taacgtgctc tgttttcagt tggcaaaagt gcatggtgat cggtcacttt actgtcttgg
    23161 aatacttttg tctgttggac gatggctccg tttttcaaat actgcttgac ctcaggagca
    23221 aagtcgctga ctgcttgcaa tcgttctttc atcgtacttt tcatgtcatt tgtcagatat
    23281 ttgctgtctg tacgcggata agtaacgatc ttatgggtct catacaaact ttgtacaaga
    23341 cttaatgttt tctttgcaga atagccatag cgttgattgg cttctctttg gatctctgtt
    23401 aaatcataag gcaatggcgc agattccgtt tttaattttt cttggacttc tgtgacagtt
    23461 cctttgcttg tactgatcaa ttgaacaagt ttttgtgctt cttcttgtgt ttttaaagca
    23521 aattgatttt tttgaagcat tttggcttgt tcttttccag cttgcaacgt gatcgtgaaa
    23581 tacgtttgtg gacggaactg ctcgattttc ttttcttggt ctctcactaa tgctagtgtc
    23641 ggtgtctgca cacggcctgc tgataaatta tccgcgtact tcacagttaa ggctctggtc
    23701 acattcaatc ctaccagcca gtccgctttt gcccgggcaa gagcagattc atacaatgca
    23761 tcatattctt tcgcaggtct tagttgcttg aatccagttt tgattgcttt atctgtttga
    23821 gaagagatcc ataaccgctt cactggttta ttgaaatgca catactctaa gatccagcga
    23881 gcaacaagtt ccccttctct tccggcatct gtcgcaatga ctgcttctga gacatctttt
    23941 cgctgagcca gctgcttgat tgcttttaat tgatgtcctg ttttaggaag tggtttgatt
    24001 cctagttttt tagggatcat tggcaacgtg tccatttgcc agctctgcca ttccttattc
    24061 agatcttccg gcattttcaa tcctaataaa tgaccaaggg cccaagtaac gatcaccttg
    24121 ggtccttcat aataattttt gtgcttttga ttagcaccaa gcaccttgct taggtctttc
    24181 gcaacgcttg gtttttccgc tagaattagt tgtttcataa aattcctttc tgctttctac
    24241 tgtgatgggc tgatgatttt tcaacaacgc aagtcccttg tattgctgta aatcatcgtc
    24301 acactcttca caccagcgct catctccgtc attccaaaag gcgctgagaa agttactttt
    24361 tgcattgata tattcataat tttgatggat ttcgttccat tgtttttcgt acgcttgtcg
    24421 tgcttcttcg aaagactcga atgtttcttc ttcttcaata tcttcttccc agtcttcaaa
    24481 aaaccaccaa ggctcattgt ccccgaacat ggtaattact tgatacatac tcgtgctcct
    24541 tctttcagct tttctagact catcttagtc acttttcaag aaagttgcaa gaattttctc
    24601 ttataaaagg gtcatttaat gaacatctta aaattgttac aaatgaatct gattgtttaa
    24661 ggcaaagtag cgataaagtt attgatcatc caaaaatagc tgtcttctgg atcgattgtt
    24721 ggttcttttg taaagtatcc taaaaaacgt aaggaaagat aaccgtggat catactacga
    24781 agttccctgc ttcgatgaac tttttcttct ttcgttaatt gaaaagcctc aaatatctgc
    24841 aaaatgatct gattcgtttc atggattcca tctaataaaa cagcttcatt ggtatgcggt
    24901 acactgatca gtaactcata cactgcttga tttgaaaaag caaaggatcg ataagtttct
    24961 gcatagatct gcagtgcttc ctgaccactt tttcccacaa gagcccgtcg cagctggtca
    25021 ttaagttcct gcagaagttt cgctgttagc gctgttttga catcacgaat atttttgaaa
    25081 tggttataca gcgagggagc cttgatatcc aagcgtttgg ctaaatgctg aaaggttatt
    25141 tgctgaacat ccatctcttc tgctagttct cgaaagcagt cgatgatttt ctcttgagac
    25201 agatttcttt ttttcatttc catgtttcct ctcataaaat aaatccttca ctctttcagt
    25261 ttaccacgaa aaagaaagag aaaaaagaga ctttcattga taaactacat attgtagttt
    25321 ataataaaga gctgtagatg aaaattttca gaaagaagga gtctaattgg ctgcaagaat
    25381 aaaggaaaaa ttatttagga aaagagaaac ttgggaacaa aacttgtttg tcttatggtt
    25441 tggaacattt atggctggta tcggatttag tttagtcatg ccttttatgt cactttacat
    25501 agatacgtta ggtaattata gtacgtcaca attgaacttt tggagcggat tgactttttc
    25561 atctactttc ttggtgacta cgcttatctc tccttggtgg ggaaaattag ccgaccaaaa
    25621 aggaagaaaa ttgatgctgt tgcgtgcttc attaggaatg gcaatcgtca tttctttgat
    25681 gggttgcgtg actagtgtgt atcaattagt cgcattgcgt ctgcttcaag ggattttttc
    25741 tggttatatc agtaatgcca ctgcccttgt cgcaactggg acgccaaaag aaaaaagtgg
    25801 tcaagttctt ggaaccttag caactggttc tgttacagga acattacttg gaccgcttct
    25861 tggcgggatc tctgcttcag cgtttggcta tcgccctacc tttttcatta cagggatcat
    25921 cttatttttc gtcttcttgt tgagtctgtt tttcgtccat gaaaaatttg tcccagtgaa
    25981 aaaagaaaac atggtttctg ccaaacagat tttcaaagac ttgaaatatc cacacgtcgt
    26041 catcggtatg ttcgtcacaa cgatgatcat ccaagcatcc aacaattcca ttagtccaat
    26101 catcagtctg tacattcgcc aattgctgca tggacatggg aatgttacgt tgatcagcgg
    26161 aatcattgct tcgatacctg ggattgccac tttgatagcc gctccaagat ttggtcgctt
    26221 aggtgacaag attgggagtg aaagaatact tgcgattggt ttgggttttg cgattctggt
    26281 ttatatccca atggcattcg tcacgaatgt ttggcaatta gctgccttac gttttttgat
    26341 tggtatctct gatgcttgtc tgctccctgc tgtccaagca ttgatcacaa aatattcgcc
    26401 tcatcaagct gctggacgga tcttcagtta taaccaatct ttccaagcaa ctggtaacgt
    26461 agtagggcct atgatcggct ccagtgtttc cagtgcattt ggttatcgcg gcgtctttct
    26521 ttcgacttct cttcttgttt tggtcaactt cttgcttgta cgacacaata cacaagagat
    26581 ccatcagcaa gaaactgcag aagaaaaagc ttcaggagtc tccatagctt cagggcactc
    26641 tccttctcat agacaataag cgtaaatgaa aaacactgct tgaacagttg tcacagactg
    26701 tccttgcagt gtttttgttt aggcctgttt tttcaagaac tcagataaga ggaataatcc
    26761 cttttccaag gtttcttttt tacaacagta acctagtcgg gcatgcttcg gtaaatcaaa
    26821 ggcacttcct ggtactaata gtactcctgt ttcttctaat aaattgatac aaaatgtctg
    26881 gtcatcttct tcgatggcta atttaatgaa agaagtagag acgtaattgg gagcgacaag
    26941 ttcaactttc ggttcattgg ctacccattg ttttaaaatc acaaggttct ctgtaatgat
    27001 ctttttgttt cgcgccaata ttttttcttt attcttcaat gcatgtacag caagatcatc
    27061 tgacaggact ccgccgcaaa tcatcgtgta gtctcgatac tttcgaaaaa cttctgccaa
    27121 ctcaggtcca gtagctgtcc agccaatacg aatacctgga atggagtagg ttttggatag
    27181 ggaattggtt gctatacctt tttcatagac atctacgatc gacaagaatt cacctttatc
    27241 cgttaaaggc gcatatactt catctatcaa tacatatgca tctactgtac gagcaatttc
    27301 tgcgattttt tctaaagttt tccgatctag caatgtgcct gtaggattgt ttgcactatt
    27361 caaacagatg atttttgttt caggtttgac taaggcttct agctgttcta aatcaaactg
    27421 ccaatcttct tcttccttca aatgaacaaa gtcaacagcg gcacctaaag atttggggat
    27481 gtcatataat tgctgataag taggaagcat cgaaacaaca tggtctcctg cttccactaa
    27541 cgcgtataga gctaaaagat tagcaccagt cgctccattc gtttgtaaga tgttttccgg
    27601 atcgacggtt tgataaagag aagcgacttc ttgtttgaaa acatctgatc cttcgatcca
    27661 gccatagtcc aatggttcgt ttttgcgttt ttcgaaaaat ttacttacgc tagtcccatc
    27721 taagccaacg agttcgtcta atgtcaatgc ttcgatcgag ctttgtgcaa tatcatatac
    27781 cgctttcttt tcccatttat ttagccattc ttctacaccg aaatttgcga ttttcatgtt
    27841 tctttccccc ttatatcttg atccagccta cagcaagcaa cccgattgaa agcagtgcgg
    27901 ccacacaaat cagcccaatc attacttttt cttttcccgt aatttgatgt ttggtttcac
    27961 gacaagcgat ccagtagaag caaaaaccag gaagataggc aatactacat aaaaggacat
    28021 aagaaaatcc tgctaaaatg atgcccatca attcaaaaac tacagcaatc ccaccgatca
    28081 ctacttgttt tttgattcct tcttttaaag aaaactggac ttgatagatc ccgacaagta
    28141 gataacaaat caaaattgcc gctgtacata aagaataggc aaattgatag gcataatcag
    28201 taactaagaa agtcaataag aatagattag tcaagattgc agtaacaact aacgaataag
    28261 ttggggcatt ttttttattc gtttttcccc aacctttcgg caacagaccg tctcgagcca
    28321 tcaacatcgt tgtttctgct gggagcatcg tccaagacaa ccaagaacca atgatcgaaa
    28381 taatcaagcc gatattgatc agcgctgctc cccaatttcc cacgattcct tttaaaatat
    28441 ttgccatagc aggttgtgaa atagttgcta actcttcttg agataagacg ccgtatggca
    28501 agatcgaagc aaggatatag ataaacaata aacaaagcag accaatgatc gatgcttgct
    28561 gggcttctga acgtttcttc gcgcggttgg ctaaaacact tgcgccttcg atccctacaa
    28621 agacccacat cataaccatc aaacaacctt taatctgcaa ccagatcgtt ccttgctgcc
    28681 ctgttccatt cactagatta tcagatacgt taccccaaaa atcagcagtg aatatattca
    28741 ctttaaatgc gataaataca aatattaaaa ataggaataa tggcactaat ttacagatcg
    28801 tcacgattgt attgatgacg ctcgctcctt caactccatt gtttactaat aaagtcagac
    28861 cccaaataaa aatacttgca aataaaatag aaggaacatt ttgtccacct ttgaatatcg
    28921 ggaaaaattc tcccatggcg ctcatcagca tcgttgcaaa agcaacattt cccagccacg
    28981 cagacaacca gtaaccccaa ccactgatga agccacctaa tttaccaaat gaagcttccg
    29041 cgtaaccgaa aataccacca tctagatctg gacgcttttc tcctaaatga ttcagcgata
    29101 ataccaaagc taaaatacca atcccaacga ttatccatga aaggatcgct ggccctggag
    29161 ctgcagaact agccagatca cttgtgatcc caaacacacc gcttccgatt gacgaactga
    29221 caaccagagc aaccagtccc catttgctaa tacccgtcga tttcttttcc atttccatca
    29281 ccctcactta taaaattgaa caaatcactt gcaaaagatt cccttctatt ttgcaactgc
    29341 tcttgcttaa caaaaagcaa ctttattcat attattggat attatgaact ttttacacaa
    29401 gtatttcaag tataaaatga ataaaaatta attttattgc aaaaaaacag ctatgctatc
    29461 caaaagaaaa ggtgtttctt ttgttagcca tagctgtttt gattcattta atatcgctta
    29521 aacgtattgt aaaacttttg tttcttgata tgcgtggtcg atcaaaccac cacccagaca
    29581 ttccattcca tcataaaata caactgcttg tccaggagtg attgcacgta caggttcgtc
    29641 gaatacgact tctgcacgat tatcatccaa taagcgaact gtcacaggaa cgtcttgctg
    29701 acgataacgg aatttcgctg tacacttgaa ttcttttggc attggttcat tcgtcgtaaa
    29761 gtggatttca cttgcatcca agcttgtggc atacaatgca ggatgatgga acccttgccc
    29821 cacatataat gtgtttgtcg ctagatcttt tcctacaaca aaccagggtt cttgcgaatc
    29881 tcctccgcca ccgatcccta gtccttgacg ttgaccaatc gtataataca tcaagccagc
    29941 atgttgtcct ttgacttcac catcaagagt gaccatattt cctttttttg ctggcagata
    30001 gttgctcaaa aattgtttga agttcttttc accaataaag cagattcccg ttgaatcttt
    30061 tttcttagca gtcgcaaggc ctgcgcgttc agcaattgcc cgtacttctg atttttccat
    30121 gccgcctaga gggaacatcg tttttgaaag ctgttcttgt gataattggc taaggaagta
    30181 agtttgatct ttattattgt ctactccacg aagcatgtgg accacgccgt tttcatcgcg
    30241 agtgacttgc gcataatgtc cagtagctac ataatcggcg ccaagatcca ttgcataatc
    30301 caagaatgct ttgaatttga tttctttgtt gcacatcacg tctgggttag gtgtacgtcc
    30361 tgcgcggtat tcggctagga aatattcaaa tacacgatcc caatattctt tttcaaaatt
    30421 cacagagtaa taaggaatcc cgatttgagc agctactttc gctacatcct tataatcttc
    30481 cgtggccgtg catacaccgt tttcgtccgt gtcatcccaa tttttcatga atattccgat
    30541 cacgtcgtat ccttgttcct ttaacaaaag tgctgttaca gatgagtcga caccgccgct
    30601 catccctacg acaacgcgtg ttttgctgtt gtctgtcatg atatcaccat catttcaatt
    30661 agattctgaa acatctacga gttgaaggtc gcaacttttc agtattttac attatacgtc
    30721 atatttctga aaatttcatc ccttaattat caagtcgtaa aaatactgtt ctactggacc
    30781 tattcagtac acaaacatga tagtcaacca aaaaatcact catcttttga gcattcgata
    30841 taaaaaattg gcatactcat aaaaagggcc agcctttcgg caataaggaa taattttata
    30901 aattgtgaaa aactattttt caaaattgct tcttatcgct taaagctgca cgtctcattt
    30961 acaacctttt ctttttagat gttatgagtt gctcagataa gtgattttgt ttactctaag
    31021 aaaaaaggga ggcaaaagat acatgaatta ctttatcagt gatatgcact ttttccatga
    31081 acgcttatta ggaaaaaacg actttgctcc gcggctcttt gcaaatgtgg atgaaatgaa
    31141 ccaacagttg atcactagct ggaatgcagt aataaaagaa accgaccatg tttatcatct
    31201 aggcgacctt gctatgcatc cgcaatatga aaaagcaaat gcagaaattt tggaactggt
    31261 cactcaactg caaggaacaa tccacttgat caaagggaac catgacagtc gcgctttttt
    31321 ccgttattta gaaaaaaatg atcctaggct tactgacgga agtcccaaat tttattttta
    31381 tgatgtaggt gccatcgtta aattcgacca tcaacaatat tacttgactc attatccgat
    31441 gttgctcggg cctaacgaca ctatccgcaa tcttcatgga catatccatc attacagcgt
    31501 acctatcgag aacgatgtca atgtaggcgt agacgcaccg gaaagagaac tcttaaagga
    31561 aaaactacca tttggcactc cgttatctga gcaacaaatc aaagaaatct atgaagcaaa
    31621 gaggaagtac gataggtcgt gaaaaaactg ccctatatca agtattaaac aaataaagat
    31681 aattactcat atttttcatt tgagtaggct tattgccaca ggaacattag gatcagaaat
    31741 ggagttgtaa caagacttct gtcacaactc cattccatac tattcgtctt tttgctcatg
    31801 gtgttctttt accagttttt tctgtaattc tttatcataa tttcgggcag ctgacgttaa
    31861 aaataaaacg attccgcata ataaaatccc gattccggaa aacaagaaca ttttttctac
    31921 ccctaaacga tcagctaatg gtcctgcaaa taataatcca attggacctg ccaggttcat
    31981 caaagagttg aagttcccta agacacgacc taaaacattc gattcataac tctgctggat
    32041 cattgccatc agcagtgtat tgaaatatgg cgttgcacaa cctgctcctg cattcaagat
    32101 aagaaagtac aagaaccctt gactatcgtt tggaaccaat ccgcttgcac cgatcgtcag
    32161 gcccataatg atgtaggcta taataatagg tttcattcgg tctttccatg ttcctataaa
    32221 actgatcagt gcaccgccta agagcattcc gactgcgtag actacttcca ctgctcccgc
    32281 ctgtccaacg gaaccaccaa agtaatctag cgtcatcaat ggatacagac tgattgctgg
    32341 catgaacaac agcatcacaa atgcaccatt gatcgttatg taccataacc ctttattatc
    32401 catcaattgc tgcagcccaa attttgcatc tttaaaaata gtaagcggaa cttccaatat
    32461 ttcaggagaa acttttggga tcttcacaaa aatcaataag ccgacaccaa aaactgcccc
    32521 caatacatct aataaaataa ggtaattgac aggaacgact gaaaacaaag ccgcacctag
    32581 agctggcgca atgatgaaat tcgctgattg gaccattcct aactgtccat tcgtccttgt
    32641 tatgtgagaa gatggaacga ttgtcggcat aatcgactgg atcgttggca tttggaatgt
    32701 ttgtgcgacc gaacgcataa acaaagacac aaaaactagc caaatcggga aggattctga
    32761 aatcgttccg actactgcta aaataagcgc gaaaatcgct acaataatat ccgtgacaat
    32821 caaaagagct tttttatccc agcgatccac tagcggtcct acaaatgggc ttagtaaaac
    32881 catgggaatc attcctagta aagtagcaaa actcaaaatt gtcgccgaac cggtttctct
    32941 tgtcaaatac cagatgatcg catattggac gaccatacta gtgattcctg acaaaaactg
    33001 tcccgataaa aagaacaaat aatttctctt ccaattcgtt aaaacgaccg actgttcatt
    33061 ttccataaac atccctcttt tctttttcat tttgtatagc gtttgcacaa caatcattat
    33121 acgggattct tttttcaaaa aatacctttt tccctaaata acaatcgttt caatttaaat
    33181 ttctttactt agaaacaata aatcagcaaa atattaaaaa taacaacatg tgttaaattt
    33241 aaaaataaaa aagacaacta atttgcgtcg tccttacaaa gttagtcatc taacaatagg
    33301 ccgtttcaaa actagttgtc tttttatatc cacagatcat tcgacttttt cgaataaccc
    33361 acggctaatc atcccatcca tcagaaaata aaatttatct tggctcattt tctgttttgg
    33421 atctttgaaa atattgactg ctttcaatcc atttgctgta gtgatcgaca ttttcaatgt
    33481 ttgaatatct tttgatacag tgatttttaa tttgaatcct tctttgcttt gcggcgtggc
    33541 atctaatggt cggatcaatt gataattgcc tccgtttgtt tctgtaaatc cattatcgcg
    33601 caatgtatat ctttttgcat caggatgcaa acgatagcta attggtgcgc ccagtaccgt
    33661 tgctgttgtt tcaaatgcca tgattttcac ctcgataaaa ttagtttctc tttattataa
    33721 aagtttatcc tgatttttac taggtttttc agttaagttc cctaaaaaat gaaggcgttc
    33781 tctcagacat ctgttcatat aagaatgact tcactagtta ttttttgaca gcacgaacta
    33841 attgatcaag gaaatactgg atgtcgtctt cggtatttcc caaaccaaag ctgatacgga
    33901 tggattcttt tagtatcggt gtatcttctc catacattgc ttctaatacg tgtgaaggct
    33961 cgatatttcc tgctgtacaa gctgaaccag tagaaatagc gaccccatta agatcaagct
    34021 tcatcagtag caaatcattt gcttcgccaa ttaagcgaag attcaacaca tgagggagtt
    34081 tattcgttaa atcaccattt acttgataag ggatttcgtt tgcttctaat gtatcaagaa
    34141 tcaattgctg gaatccttta tatttgttgt tacgtgcttc acgttcttca ggtgacagca
    34201 gttcaactgc ttttgccata ccccagatcc ctgctaaatt ttctgtacct gcacgccgct
    34261 tttcttcctg ctccccgcct aaaagcaatg cagggatatt tactccgtct cgtttatata
    34321 agaaaccgac gccttttggc ccattgattt tatgagcaga gatacttaat aaatcgattc
    34381 ctaattcttc tggatggatc gtttggtttc cgtacgcttg taccgcatct gtatggaaat
    34441 aagctggatg atccgctaaa agttcaccga tttctttgat tggcatcaaa tttccgattt
    34501 cattgttccc gtacatcaca gagaccaaga tcgtatcttc tcgtaacgct tttttgacct
    34561 cttcgatcga cagattccct ttttcatcta caggcagata tgtaacgtca aacccctttg
    34621 tctctaaata tttcatggta ttaagaacag caggatgttc gatagctgta gtgattagat
    34681 gtctgccttc tttttgacgc gagaacgctg tttctaagat agctgtatta tccccttctg
    34741 ttcccccact gttaaagatg atctcgtgag gttttgcttg cagactgtct gcaatgattt
    34801 gtcttgctgt ttccaatttt tcatgcgcgt ggcgaccaaa tccatgtatg cttgaaggat
    34861 ttccaaacgt gtcttgcatg attgccgtca tcgcttcaat tacttgtgga tgcatggggg
    34921 tagttgccgc atgatccaga taaatagttt tcacttcatt catcccttcc aaattattgc
    34981 taggcacatt ctagcataaa atagcgaaca aaccaaagaa gagctcattt ttgtctagag
    35041 gacgtttcat gggcatagaa aaaaggagct gtgacaaaag tcttgtcgca gctccttgaa
    35101 gctgctcact tctgtcacaa cttctttccc tctttttttt gtttattcga attctttttc
    35161 ttccagacgg aataacggac tcatcggtgt attttcatgg atgcgtttga ccgcttcacc
    35221 cattaattct gaacatgtaa cgattgttaa gttttctgga tgacgatttt cttctgtgaa
    35281 aacagaatca gtgatacaaa tatctttgat tggtgcattg tctaaaatac ttttcgcatg
    35341 atcggacaat aatccatgtg acgcacaggc atatacttct tttgcgccgt tttcttttaa
    35401 tacatttgct gctcgtgcaa gcgttgctcc tgtgttcaag atatcatcta ccatgataca
    35461 tgtctttcct tgaacatcac cgatcacata accaccctca gttgaagcat catctgcatg
    35521 atctacgatg gctaatgtgc tgttcaaata ttctgaaaga ctacgtgcac gctgaacacc
    35581 gctgtttttt ggcgaaacaa ctacgatgtc atctcccgtc agacctaatt gacggtaata
    35641 atgagcaaac aacggcatcg taaataaatt atctacagga atatcaaaga atccttgtac
    35701 ttgaaccgtg tgcagatcta aagtcagtac tcgagttgcc cctgcttctt cgatcaagtt
    35761 agcgatcaat ttcgcagtga tcggttcatg aggtttcgcc gtgcggtctt gcctagcata
    35821 cccatagtaa ggcaatacga cattgatcgt tttcgcactt gctcgcttca ttgcatcgat
    35881 catgatcagt agttccatat agtaatcatt gacaggtgca ttcgttgatt gaacgatata
    35941 cacatgatcc cctcgaatac tttcttcgat attgatggaa atctcgccat cactaaattg
    36001 cttcacgacg cttttaccta attctgttcc gaacactttc gcgatttttt cagctaatgg
    36061 acggttgcca ttcaaactaa aaatcttcaa cgtgtcatcc tgatacttat tactcatgta
    36121 gtcctcccca aaacttctct attcttcgat agtttaacat atttttccaa gattttctgt
    36181 taatttcagc aaattcttaa ggaagtgaaa ctgttccgtt actccaactg gcaggaatga
    36241 ctttatgata atcgccccag ttgtcgtgta ctttgtaata acgttctcct gtttcagttt
    36301 caaaataagc gtacgctgtc acccaatgat tgccatatgt actgccaagt actttcaaaa
    36361 taccaatcat cacaggtttg ccttcacgta tacgttttgt agctcgctgc catgaaccta
    36421 gaagagttgc tcgtgcacgc tcatgattgc cattcttctt taaaaaacta gaaatccctg
    36481 tactaacctg aaaaggaatc gtaggaagtc ctagtggttg gatctggcta cgcaatgcct
    36541 tcgtcaaaac caacgaatca gccgtatttt tcttgcgaat ctcatttgga agcatccacc
    36601 ccttacgata gtcttgataa taggcaagga gaactgctgc cgcgtaagta ccacaaagat
    36661 agcctgaggg ggtagcccat ttcttatacc tcaaaaaacg ttcttctggc aatcccaccc
    36721 agcaatttgc gagttccttt cctgaccttt tttcttcgat caaaacggga atatcttctt
    36781 ttctgttgat ccatctagat aactcgattg gctcttcatt gatcagcttc cattttttac
    36841 aagaaagacc ctcttgataa gtatattttg ctggagaata ttctaccgga tgtcctgatt
    36901 gatcgataat cacataactt tgatcttcaa aaaccagagc taaaaaaagc aatttacttt
    36961 ttcttgactg cagctgctga gtgctggcta attttttaat ttttttatct actttgaaat
    37021 ataaaggttt atccactact tgattcagtt gggatcgcct cctttttttc attataagtg
    37081 aaggattgaa aaaaacaaat cagtttgatt gttcgaattt tcaatttttt atgttctatt
    37141 tgttaattcc ttcattttgt aagataatgg gcacacgaaa caaaaaagga gcgatcgatg
    37201 aatgaacaaa gaacgattga aacaagattt ctatgaagca gtcaatgaag aatggcaaaa
    37261 aacagcaaaa atccctgcag ataaaccagc tacaggcggt ttccaagatt tagttgacgg
    37321 gatcgaccaa cttttgatgg gagaaacaga cgatctgctt gcccatccag aaaaagtgtc
    37381 ttcagaaaaa atgaaacatt tccttgcata ttatcaactg gcaaacgatt atgaccgaag
    37441 aaatgagttg catgctcaac cgcttcaacc tataatcgaa aaagttgaat cattgcagtc
    37501 tttcgacgaa ttgaataagc aatttccaga atggctgttg gatacattac cattgccatt
    37561 taatctggat gtagatgcag atatgaagaa tgcgcaaacg aacgccttct ttgcttatcc
    37621 gccttcttta ttccttccag ataagacgta ttatgcatca gaccatccca acggtgcaca
    37681 actaataggc gttttctttg atatggctgt tcagttatta gagcttgccg gcaaagaaaa
    37741 aagtcaggca gaagcaatca cggaacaagc agtgcaattt gataaattga ttgctcctca
    37801 tgtaaaaagt gcagaagaaa acgcagatta cagcaaaatg tataatccgc aatcttttga
    37861 tacatttatt aaatacacag ataaactgga cttgaaaaaa cttgtcacgg gtttgattgg
    37921 gacaactcca gataaagtga tcgtaactga tccagtgtac ttcgatcatt tgaatgacat
    37981 cctgacagaa gctcattttc cgttattcaa aagctggatg atcattaaaa cagtacgttc
    38041 tcttagtggt tatctatcag aagaattccg ccaagtcagc ggaatctatt ctcgcgtatt
    38101 gtctggaaca gacgaagcaa tgcctcagaa aaaagcagcg tattaccttg cctctggaca
    38161 attcgatcaa gtagttggcg attactacgg aaaaaaatat tttggcgaag ctgctaaaaa
    38221 agacgtagaa caaatggtga aaaaaatgat cgccgtttat aaaaaacgtc tagaagaaaa
    38281 tgactggctt ggggatgcaa caaaagaaaa agccgtcata aaattaaata acttaggtat
    38341 ccaagtaggc taccccgata agatcccagc attattcgac cagttcaaaa cagtacctgc
    38401 agatcagggt ggtactttgc tttcaaatac tcttgttttc agcaaactca cattaaaaga
    38461 tcgtttcagc aaatggaaca aaccagtgga tcgttcagaa tgggaaatga gtgctgacac
    38521 ggtcaatgct tattatcatc catttcggaa tgtgatcgtc tttccggcag cgatccttca
    38581 agcaccattt tacagtctag aacaatcaag ctctgctaat tatggtggaa tcggagctgt
    38641 tatcgctcat gagatttccc atgcatttga taataacggc gctttatttg acgaatatgg
    38701 caacttgaac aactggtgga cagaagaaga tcttacacaa tttcaaaaca aagcacaagc
    38761 aatgatcgaa gaattcgatg gtctgccttt tgctgacgga aaagtaaacg gaaaattaac
    38821 cgtttcggaa aatattgctg atgcaggcgg tctaagctgt gcattggaag cagcaaaaac
    38881 ggaatcagat ctttctatcg aggaattctt tgtcaattgg gcaacgattt ggcgtacaaa
    38941 agcaaaaaaa gaataccaac aacttttact gcaaatcgat gtccatgccc ctgctaaact
    39001 ccgagcaaac gtgcaaccaa aaaaccttga cgaattctat gaaacatttg gtatcacgga
    39061 acaagacgct atgtatctag cgccagaaaa aagagtgcga atctggtaag aggttgtgcc
    39121 agaagtggtc agcttcaaga aataagaagg aatttgggaa aatcgcttct caaatttttg
    39181 tgacatttcg gcttattttt cgaagaagtt acttctggaa taccatgtat tagaggttgt
    39241 gaaaaagctg cttagtttca agtagtaaga aaaattttgt gaaaatggct ttccacattt
    39301 ttgcataaat ttgacttact accgagaaac tggcttttga acaccgttta tcgagaggtt
    39361 gtgaaatcag cgtcctgacc tgagtattag agaaaaaaac ggaaaaatag ttcctcatat
    39421 tttgccgttt gttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaga
    39481 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaagc agcaaggaga
    39541 acctcatcta taaaaagata gaaggaagtg agacatctat tggtctcatt tccttctatt
    39601 tttactttcc tcagtcaatt gttttacatc ataaaaggag aaattccact tatttttttc
    39661 gctgtttcat gacataaaca actacaccga ttaacaaaat tcctccagct aatgctagca
    39721 acgggttatt aaattctccc gtttttggga gtccttgagt gccatttttt tcactttctt
    39781 ttgctgtcct atccggatga gaaggttttc catttggttt tccatttggt gattcatttc
    39841 ctggattttc tctttctggt ttgtcatttc ccgggggcac atcggcagtt tctcgcacag
    39901 tgatcgcttt ttgctgggta acagattctg tatgagcaga ccatttttcc ccatcaaata
    39961 tttccgaacg ataagtgact tctagcgtat attctccttt tgaaggtgct gaaaaaatag
    40021 cggtatgatt agaaaattga gcacttgact gtgtttcaac gatttggatc ttttctggga
    40081 aataacgcat atcttcaaag acaggcgttc cttgatttgg tgtgaaagtt gacacaaaaa
    40141 ctgtaaaagg cttcagttca atgatatttc cttctgcatt ctccgccaca ccatttgctt
    40201 cttgtataat aatcggatta ttttgttcat ttggttttgt ctgatttggt tcttgtacga
    40261 ttgcatactc tggatattcc gaagacggtg aggtttctcc gtcaaaaata gcacctacag
    40321 ataatggaag accatccact ctttcctttt ctgtttgacg attccccggt ttaatctgca
    40381 tcagtccatg aacatggata cttccatttt catagcgcgt aacaggctgc tgaccttctt
    40441 tcgaacatgt atttagagac tcgatccaat cttttgatat ggtatgtcca agagtatttt
    40501 ctgattgttt ctctcgttca ttccaatagt agttcaacga gtggtagatt tgatcttcgt
    40561 tttgattcaa tgggcggatc tgctctctca tctcaagatt ctctgttcgg aaagataaga
    40621 taccagaagc atggtagtct gtgtttcctg ctgaagaggt ataaagagcc acattatatg
    40681 aaccgttatt aaaacttgta ctgctattga cgataatatc tgttccgcta ttggaatcga
    40741 ttcctttcgc aagattttcg aaagacaaac tattgatcaa ttcatgaggg cccgttaaag
    40801 aagaaccgcc cattttgaat ccattaccgt taccttctcc ctcaattcct ggtacccagc
    40861 cgtttcgata agcaactgag tttttgatga ttacttttcc gatcgaacct gtttcatttt
    40921 tagcaaaaag gtcccaaccg tcatctgcat tatgatacgc gatacaaccg tcaaatacat
    40981 ttccttctcc tattgtcagt ttggccgcaa atccatcggc atcttcaaat cctggatcgg
    41041 cattttcaaa agatgtacag ttcttgacta agttatgcgc gggccatgct tcgaaaggat
    41101 catttgagct accgctgatt tggattcctg tatttccatt ccgataagca tgaatctctt
    41161 cgatcaaatt atgatttcca gaaatctgta atcctttttg catagctgca ctatttgtaa
    41221 tgtcaaaccc tcgtaaaccc cagtagtgac tgaacagtgt catcccattt ccagttcctt
    41281 taaaatcaag tacaggacgc ttgttttctg gatttttctc tgcaatcaac tgaatcgggt
    41341 tttctcttgt cccgttaacg ccttttggaa tcgtcaatcc tctttcgaag gaataagttc
    41401 caggcgccat gacgattgtc tgcccagcat atgcgtatct caatgcttgt gtcagagata
    41461 atggattttg tctgcttccg tttcctgcat ctgacccttc tggtgttaca taaactgtcg
    41521 aatatttagg tttacggtag tccactgtat gaagaatctc ttttgtttca taactagtca
    41581 tctctacgta ttcttctggc ggatagtttt tatctggcgt aaaactgaaa gtaaattcgt
    41641 tcgttccttc catcagtttt gtctgataat caaattcccg attcgcagtg atagccaagt
    41701 tttttgcgtt cttaagcacc tctcctgttg ctttattttt aattgtcaat aatccgtcag
    41761 catttgctct aaaggacata gtatgatctt ggtttcctga atgattacta gaggtcacag
    41821 tgtaaatcgg atcaatcaag cgagtaggtc tttcttgccc aggaggatct gtcgcaggat
    41881 ctgagtaagc aacttcgatt ccttctacct tgatcgtcat attccttgct gcagcaaatc
    41941 ctgcataaat aaccgattca tctgaagcgt ataatttttc ccagtcatac atgatgtcag
    42001 aagccatttc ttctcctgtt tcaggatcgt aataatatgc ctctaaacca gtattcgttt
    42061 ttttcatctc tacgtccagt ttagtaatcg agttcgtggc cggaaacaga ttcccatgac
    42121 cgtttccgaa tatattataa gaacctgttt ctttttccaa gaaccctgct gaagtctcta
    42181 aaggtgttgt ttccactgag acactcccag gagctggcgc agcttgcgga tcttcagatg
    42241 atattcctgt gattgcccgt gtccccaatc caagtcgcat cgtatatttg ctgccgctcg
    42301 tgttgaccac ttcttgtcta tccgagtccc agacatattc gatccgactg cctagtatgg
    42361 caaatgaatt tgaataaaat gcctgcccaa acaaatgatt ttttggtact gcgtctctta
    42421 ccattaaagc aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg
    42481 cccgcatcct aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg
    42541 atccgcttga ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta
    42601 atggttcaat ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact
    42661 cttcatttgc ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag
    42721 gatcatttcc ttcttccgta tccatatctt cactagttct tggtatttcc tccattgttg
    42781 acatcccttc aatgttcacg tgtgcatttt cttcgttcac agactgttgt tcgttagcag
    42841 caacttcaac gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg
    42901 cactgtattt tatacgtttt tttaacaagt gtattcctcc cgtaacaaat tagaaagcgt
    42961 ttacttaaag tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt
    43021 gtattttata aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg
    43081 gaaaa
//
LOCUS       DAIGQM010000017        42515 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.017, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000017 DAIGQM010000000
VERSION     DAIGQM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.017"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..594)
                     /locus_tag="NOA48_000912"
     CDS             complement(<1..594)
                     /locus_tag="NOA48_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789197.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDE"
     gene            787..1818
                     /gene="queA"
                     /locus_tag="NOA48_000913"
     CDS             787..1818
                     /gene="queA"
                     /locus_tag="NOA48_000913"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCI0789198.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            2437..5076
                     /locus_tag="NOA48_000914"
     CDS             2437..5076
                     /locus_tag="NOA48_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0789199.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(5244..5942)
                     /locus_tag="NOA48_000915"
     CDS             complement(5244..5942)
                     /locus_tag="NOA48_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0789200.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            6160..7305
                     /gene="tgt"
                     /locus_tag="NOA48_000916"
     CDS             6160..7305
                     /gene="tgt"
                     /locus_tag="NOA48_000916"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCI0789201.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            7402..7782
                     /gene="yajC"
                     /locus_tag="NOA48_000917"
     CDS             7402..7782
                     /gene="yajC"
                     /locus_tag="NOA48_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCI0789202.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            8087..10684
                     /gene="adhE"
                     /locus_tag="NOA48_000918"
                     /gene_synonym="adhC"
     CDS             8087..10684
                     /gene="adhE"
                     /locus_tag="NOA48_000918"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCI0789203.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            10913..12019
                     /locus_tag="NOA48_000919"
     CDS             10913..12019
                     /locus_tag="NOA48_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0789204.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            12036..13060
                     /locus_tag="NOA48_000920"
                     /pseudo
     CDS             12036..13060
                     /locus_tag="NOA48_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            13066..13545
                     /locus_tag="NOA48_000921"
     CDS             13066..13545
                     /locus_tag="NOA48_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCI0789205.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            13561..14340
                     /locus_tag="NOA48_000922"
     CDS             13561..14340
                     /locus_tag="NOA48_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HCI0789206.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYKWVIRF"
     gene            14304..14627
                     /gene="kduI"
                     /locus_tag="NOA48_000923"
                     /pseudo
     CDS             14304..14627
                     /gene="kduI"
                     /locus_tag="NOA48_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            14647..15450
                     /locus_tag="NOA48_000924"
     CDS             14647..15450
                     /locus_tag="NOA48_000924"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCI0789207.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(15699..16763)
                     /locus_tag="NOA48_000925"
     CDS             complement(15699..16763)
                     /locus_tag="NOA48_000925"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCI0789208.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(16760..17845)
                     /locus_tag="NOA48_000926"
     CDS             complement(16760..17845)
                     /locus_tag="NOA48_000926"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCI0789209.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(17858..18835)
                     /gene="mvaD"
                     /locus_tag="NOA48_000927"
     CDS             complement(17858..18835)
                     /gene="mvaD"
                     /locus_tag="NOA48_000927"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCI0789210.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(18828..19772)
                     /gene="mvk"
                     /locus_tag="NOA48_000928"
     CDS             complement(18828..19772)
                     /gene="mvk"
                     /locus_tag="NOA48_000928"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCI0789211.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            20087..20746
                     /locus_tag="NOA48_000929"
     CDS             20087..20746
                     /locus_tag="NOA48_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0789212.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            20831..21736
                     /locus_tag="NOA48_000930"
     CDS             20831..21736
                     /locus_tag="NOA48_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0789213.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(21738..22370)
                     /locus_tag="NOA48_000931"
     CDS             complement(21738..22370)
                     /locus_tag="NOA48_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0789214.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    22521..22646
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            22690..23214
                     /gene="infC"
                     /locus_tag="NOA48_000932"
     CDS             22690..23214
                     /gene="infC"
                     /locus_tag="NOA48_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCI0789215.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            23286..23486
                     /gene="rpmI"
                     /locus_tag="NOA48_000933"
     CDS             23286..23486
                     /gene="rpmI"
                     /locus_tag="NOA48_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCI0789216.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            23539..23898
                     /gene="rplT"
                     /locus_tag="NOA48_000934"
     CDS             23539..23898
                     /gene="rplT"
                     /locus_tag="NOA48_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCI0789217.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            24250..25488
                     /locus_tag="NOA48_000935"
     CDS             24250..25488
                     /locus_tag="NOA48_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCI0789218.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAES
                     YTYNDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLL
                     PVLGVVLLDLPIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGF
                     LMTLAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFHGPMNLVGSGSA
                     ILAVVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIP
                     TGWIIGAILCLITFLLYGNA"
     gene            25536..27665
                     /locus_tag="NOA48_000936"
     CDS             25536..27665
                     /locus_tag="NOA48_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCI0789219.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            27640..28329
                     /locus_tag="NOA48_000937"
     CDS             27640..28329
                     /locus_tag="NOA48_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789220.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFVTYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(28737..29423)
                     /locus_tag="NOA48_000938"
     CDS             complement(28737..29423)
                     /locus_tag="NOA48_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0789221.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(29559..29753)
                     /locus_tag="NOA48_000939"
     CDS             complement(29559..29753)
                     /locus_tag="NOA48_000939"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789222.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(29803..30243)
                     /locus_tag="NOA48_000940"
     CDS             complement(29803..30243)
                     /locus_tag="NOA48_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCI0789223.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(30247..31092)
                     /locus_tag="NOA48_000941"
     CDS             complement(30247..31092)
                     /locus_tag="NOA48_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCI0789224.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            31241..32659
                     /gene="pepV"
                     /locus_tag="NOA48_000942"
     CDS             31241..32659
                     /gene="pepV"
                     /locus_tag="NOA48_000942"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCI0789225.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(32735..33937)
                     /locus_tag="NOA48_000943"
     CDS             complement(32735..33937)
                     /locus_tag="NOA48_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789226.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(33924..35711)
                     /locus_tag="NOA48_000944"
     CDS             complement(33924..35711)
                     /locus_tag="NOA48_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789227.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(35724..36677)
                     /locus_tag="NOA48_000945"
     CDS             complement(35724..36677)
                     /locus_tag="NOA48_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0789228.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            complement(36862..37212)
                     /locus_tag="NOA48_000946"
     CDS             complement(36862..37212)
                     /locus_tag="NOA48_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0789229.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            37412..38491
                     /gene="pepA"
                     /locus_tag="NOA48_000947"
     CDS             37412..38491
                     /gene="pepA"
                     /locus_tag="NOA48_000947"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCI0789230.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            38634..38954
                     /locus_tag="NOA48_000948"
     CDS             38634..38954
                     /locus_tag="NOA48_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0789231.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTASWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            38976..39440
                     /locus_tag="NOA48_000949"
     CDS             38976..39440
                     /locus_tag="NOA48_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0789232.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            39647..40252
                     /locus_tag="NOA48_000950"
     CDS             39647..40252
                     /locus_tag="NOA48_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCI0789233.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(40291..41580)
                     /locus_tag="NOA48_000951"
     CDS             complement(40291..41580)
                     /locus_tag="NOA48_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCI0789234.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42009..42488
                     /gene="rlmH"
                     /locus_tag="NOA48_000952"
     CDS             42009..42488
                     /gene="rlmH"
                     /locus_tag="NOA48_000952"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCI0789235.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT        13468 a         7879 c         8879 g        12289 t
ORIGIN      
        1 ttcatccatg tcatgggtta caaatacgat cgtttttccc aaacgctctt gtaaatcttt
       61 gacaaggtct tgcaaggaat cacgagtgat tggatcaagc gcaccgaatg gctcgtccat
      121 caagatgata tcttgattcg ctgcaagggc acgaacgact ccaatacgct gctgctgacc
      181 accagataat tcatgtgggt agcgatctaa catctcacgg ggcaattcca caagatcaat
      241 cattttttca gctgttttat tccgttcttc ttgactgact ttcaacaatt tttggacaag
      301 agtgatattt tcacggatcg tcatgtgagg catcaatcca atactttgga taacatagcc
      361 gatctgacgt cgcaattcca ctggatcaat ttcttggatg gattttccat caatcaaaat
      421 tttcccttgt gttggatcag tcattcggtt gatcatccgc atcgtcgtcg tttttccgct
      481 tccgctcgta ccgataaaac aaatgaactc acccttttca aatgaaagat tgacgtcctc
      541 tacagcgact tttccacctt tataaatttt tgacacattt tgaaattcaa tcatggtgcc
      601 acctcttttt ctattttcaa tgaagaacta tctattacta gtatgcctaa aacaatgaaa
      661 aaatacaaat agggtagttt ttttatttag gaaaacaaaa aatagaagtg aaaaagtgct
      721 gattttgcca acagaacgaa aaacatgata gaatgatgaa gcacatgata gaaagtgagt
      781 gacgatatgt taacaacaga agattttgat tttgacttgc cggaagaatt aatcgcacaa
      841 acaccattaa aagaccgcga tcattctcgt ttacttgttt tggatcggaa aactggagag
      901 atggaagata aacatttcca tgaaatcatt gaagagttac agcctggtga tgcgctagtt
      961 atgaataata cacgagttct gcctgctcgt ttatatggag aaaaaccaga tactggtgcg
     1021 catttagaag tccttcttct aacgaataca caaggagata cgtgggagac attgatcaaa
     1081 cctgcgaaac gtgccaaagt tgggacaaga atctcttttg gtgatggcag attgcaagca
     1141 gtagtgaaag aagaattgga acacggcgga cggatcattg actttgagta tgaaggaatt
     1201 tttctagaga ttcttgaatc attgggagaa atgccattgc ctccatatat caaagaacgt
     1261 ctggaagacc cagatcgcta tcaaactgtc tatgcgaaag aaaatggttc tgctgcagcg
     1321 ccaacagctg gattgcattt tacgaaagaa ttacttgatg agatcgaagc aaagggtgtt
     1381 gaattagtct atctgacact acatgtaggg ttaggtacat tccgacctgt cagcgtagat
     1441 aaaattgaag aacaccatat gcatagtgaa ttctaccgtt tgacggaaga agcggctgag
     1501 cgattgaacc aagtacgtaa aaatggcggg aaaatcgtgg ctgtcggaac aacttcaatt
     1561 cgaacattag aaacgattgg aacgaaattt aatggagaaa tcaaagcaga cagcggatgg
     1621 actgatattt tcattacgcc tggctatgaa ttcaaagtgg tagaagcttt ctcaactaat
     1681 ttccatttgc caaaatcgac tttagtcatg ttagttagtg cctttgcagg aagagaattg
     1741 actttatctg cttaccagca tgcgattgaa gagcgctatc gtttctttag ttttggagat
     1801 gcgatgttcg tgaaataagg ttatgaaaag ccgctagttt tgaataacaa aaaagcttta
     1861 caaagatttt atgacaaaga aaaagccgag ctctcgataa gctcggcttt cttgtacctc
     1921 ggaaggattc aaataaacag aaatgattgt aactttccat catacatgca aagcacggtg
     1981 ttgaatttct tcatgttaaa caaaaatttt gttttcgtta catcttcaac atttgaaaca
     2041 tctcttgttc ctattcaatt ttcagacgtt tacgttattc aattgttacg tatcgcatta
     2101 cttcttgttt cggatacttc gtgatccaaa catccatacg cattcactat ttataggttt
     2161 gtactctaca cgcatgtctg ggtgaaacct gtacttctaa caactttgtt tgcttacact
     2221 gttctatcga gaaattcttc tgtctatttg atggtatcct ccttccttac atctatataa
     2281 tagcatcctt tggtagcgtt tgcaaatata agcactttaa attttacgct ttcttaacaa
     2341 ataatcgata agccctttat ttgaagtaaa taaaaaaagg atgttatagt aaaataagta
     2401 cctttttttg tacgaagatt ttaaaggagg aataggatgg aagaatacaa gcagacaata
     2461 gaagaagtaa agaaggtaac agaagcagat ccagatactg ggttgtcttc acaagaagtg
     2521 gatgaacggc gaaaaaagca gggattgaat aaattcgatg aggcgccgaa agaatcgatg
     2581 atcaaaaaat tctttcgaag cttgtccgat tttacaacga tcatccttct tgtagcagcg
     2641 gtgatttcct tttataccgc atttgctaca gaacatgggg atttatttga aggactgctg
     2701 atcatcgcta tcgttgtgat caactcggta ttggcgattg tccaagaagg aaacgcagaa
     2761 aaagcactgg aatccttgca agatatgaat aaacaaacgg caactgtcat acgagacggc
     2821 aaagtgacca ctgttgagtc agagcaactg gtagtgggtg atattcttgt tttagagtcc
     2881 ggtgatgcta tttctgccga tgcccgtttg atcgaagcat cacaattacg tgtagaagaa
     2941 tcggcgttga ctggagaaag tgaagcagtt gaaaaagatg cagcatttat tgctgaagaa
     3001 gatgagtcat taggtgacca acttaatatg gtatttaaag gatgtacggt tgctgcaggt
     3061 cgtgggaaag cgatcgtcac tgccattggc atggctacag aaatgggtaa gatcgcggat
     3121 cttttgaacg aaaatactat gcaaaaaaca cctttacagg tccgattgaa tcagctaggc
     3181 aaacgaatca gtatgatcgc tttagcggct gcggctttag tatttgtgat tggtgaactg
     3241 caaggagaac cactccttga gatgttcatg acttcgattt ccttggctgt tgcagctgta
     3301 ccggaaacct tgactgttat tgttacgttg acacttgcat acggtgtgca gaagatggcg
     3361 aggaaacatg cgatcatccg acagttgcca gcagttgaaa cgctaggaac cgctaatgtt
     3421 atctgctcag acaaaacagg aacgctgaca caaaatgaaa tgcgcgtccg ccgggtatgg
     3481 agcaaagaag atgaagtaac gaatatcgaa gattcaatga cgaacagcgc gatggaaata
     3541 ttgaaaatgg ctgcactatg tacagatgtg acggtcgagc aagaagatga cgaccttgtt
     3601 atcaaaggta atccaacaga agtagccatc gtaagggctg ttgaagagaa ttatcataca
     3661 aaggcagaat tagaagaaaa atatccacga gtaaacgagc ttccttttga ttctgaacga
     3721 aaaatgatga caacagttca ccaaatgggc gaaaaataca tctcaatcac caaaggagca
     3781 ttcgatgttc ttgctccgcg ctttagttca ggcgatgtag aacaagcggc gatcgttaat
     3841 gatcgctttg gtaaacgggc actgagagtg attgctgttg gttatgctac ttatgacgaa
     3901 gaaccgcaag atatttcttc tgaagcactg gaaaaagact tacgtttgat tggtctgatc
     3961 ggaatgatcg atccaccacg tccagaaagt aaaggagcaa tcaagcgagc gaaaaaggct
     4021 ggcatcaaaa cagtcatgat cactggagat catgtggtga ctgccagtgc catagcgaaa
     4081 gaattaggta tcttgaatga tccgtcagaa gcactttcag gatcagaact gcatcaatta
     4141 tcagacgaag aattagatgc gcgtgtcaaa gctctctctg tctatgctcg ggtaacgcca
     4201 gaagacaaga tccggatcgt caaatcttgg caacgtacgg gtgcagtcgt agcgatgact
     4261 ggggatggtg tgaatgatgc accagcgttg aaagcaagta acgttgggtg tgccatgggg
     4321 atcacaggaa cagatgtggc gcaaagtgcc gcagatatga ttttgacgga tgacaacttt
     4381 gcgacgatcg tagacgctgt cagtcaagga cgttcggttt atcagaatat tcgtaaagct
     4441 atcaactttt tgctaagctg taatatttcg gagatcttta ttgttttgat tgcgatgctg
     4501 ttaggatggg gagcaccatt tacagctgtg caactactgt ttgtcaatgt agttgctgat
     4561 ggacttccag gatttgcttt aggaagagag ccagcggaac acggcatcat ggatcagcca
     4621 cccattccga aaaatgaagg gatctttgct cgaggtttat tgcaaaaaat tgccataaat
     4681 gcaggggtct tcaccatcgt aaccttgttt ggttattatt taggtagtta tgtcgatact
     4741 atcagcccat gggtagacgc aagtcagcat gtcggtcaaa ctgttgcatt cttgatctta
     4801 gcttattcat cgattctgca tgtgttcaat gtacgcagca gccaatcgat cttcaaagtc
     4861 aatttagcga ccaataaagc tttggtagaa atggcgttac tggcattagc tattacaacg
     4921 gctgttgctt tgctgccatt tacgcaagaa ctattcggcc tagtacacat cagtttgaat
     4981 cactggttct tggtagggat tttatctatc gtaccaatcg cggtgaatga actgatcaag
     5041 ttccatcgat taccggaagc agaagaagag gaatgattaa ctgtttctaa gttgattttc
     5101 tttttactgg aactatacaa aaaggaggtg tgacatgaat gttgtcacac ctcctttttg
     5161 ctaatgggct gaatgtttct tttactgcct ctcgataaac ggtgttctcc tgccaccccc
     5221 tcggtcacaa gtcacactct cttttaaata tcttttggca attgttcata aaatgctgct
     5281 tttgttgcag aaatgtatgg gctgagccat agataaccaa taccagcagt tgctaatgct
     5341 aagatatgcc agccgataaa tgaaagatct aaccagaaaa gttgtccttt ataaccatcc
     5401 atcaattttc gacttgcagt gatcgtatcc agtactttag gtgtttgtcc tgtttcttgg
     5461 acgatatcgt agtaaataaa atagctttga gaataagaat agcttttaat gattccagga
     5521 ataactaata gcaaacccca taatgttgta aagatcgaga tcagcacagc taagctgatc
     5581 actccgccga taaacaaacc tttgaatcca cgaaatgcat ctttgaatgg ttcgatctga
     5641 tctttttgtc cacgtaaaat atcaagataa gtccaagaaa taccgctcat gaacaaagcg
     5701 ctaatgatgc tggaaataat tccgccaccg cctcctgaac taccgcctcc tgaagttgtc
     5761 gcttctgaga cgctcgctga tccatcatat atggtggtgg caaacaagat aataggaatc
     5821 ataataagaa gaatagtagc aataccaatc aatgtaggga ttagatttag taaaacagct
     5881 tgtccccaac gtccttttag actctctttt gcttggcgtt ttaattctgc agaagattgc
     5941 atgatttttc cctccttttc tttaataaca ccaatatacc atgtatcaaa aaatatttct
     6001 gtcataatgt ttttcttttt tttgttattc ataaaaaaag gataaaaaaa agaatattaa
     6061 ataaagtaga aggaagccga gggaacttgc aaaaagcact tgaaacgatt atgatggtgg
     6121 gagttgtcaa gatattttat atagaaagta gggaaatgaa tgacgcaacc tgccattcgc
     6181 tatcgtttaa tcaagaaaga aaaacatact ggcgcgcgtt taggggaatt gatcacgcca
     6241 cacggaactt tccccacacc aatgttcatg ccagtaggaa cattagctac agtaaaaaca
     6301 atgtccccag aagagttgaa agaaatgggt gctggcgtta ttttaagtaa tacatatcat
     6361 ttatggctac gccctggtga agacttagta gaagaagctg gcggactgca taaatttatg
     6421 aactgggatc aaccgatttt aacagattca ggcggctttc aagttttttc attaagtgat
     6481 atgcggaata tcgaagaaga aggcgtgcat ttcaaaaatc acttgaacgg ttcgcgtatg
     6541 tttttatcac cagaaaaagc aatcaacatc caaaataaat tgggctctga tatcatgatg
     6601 agttttgacg aatgtccacc attcgatgaa agttacgact acgtgaaaaa atcagtagaa
     6661 cgtacgtctc gatgggcaga acgaggattg aaagctcatg ctaatccaga ccgtcaagga
     6721 ttatttggaa tcatccaagg agcagggttt gaagatcttc gtcgtcaaag cgcgaaagat
     6781 ctagtcggga tggatttccc tggttactca atcggcgggt tatctgtcgg ggaacctaaa
     6841 tcagaaatga atcgtgtatt agaattcact acaccgttga tccccgaaaa caaaccacgt
     6901 tacttgatgg gtgtcggtgc tgctgattca ttgatcgatg gtgttatccg tggagtagac
     6961 atgtttgact gtgtcttgcc tactcgaatc gctcgaaatg gcacatgtat gacttctcaa
     7021 ggccgtctag tagtgaaaaa tgcgaaatat gcccatgatt tccgtccaat tgatgagaaa
     7081 tgtgattgtt atacatgtaa aaactataca cgtgcctata tccgccattt gatcaaatgt
     7141 gatgaaacat ttgggattcg tttgacttct taccacaatt tatacttctt gttgaatcta
     7201 atgaaacaag tacgtcaagc aatcatggat gataatttgc ttgaatttag agaagccttt
     7261 tttgaagaat acgggttcaa taaagaaaac gcaaaaagct tctaaaggaa aatcttttaa
     7321 aaattaagta aaaaactagt gttatcagca tttttctgct aaagtgtttt ttgtagatac
     7381 agaattagtg aggtgaaaaa aatgggaaca ttaccaatgc ttgtgatgtt tatcgcgcta
     7441 ttagcaatgt ggttttttat gtcacgttcg caaaagaaac aacagcaaga acgtcaaaac
     7501 ttgttagata gcatgaaacc aggtgattca gtcgtaacga tcggcggatt acatggagtt
     7561 gtttcagaaa tcgacaatga caaacggaca gttgttttag actgcgaagg gatcttcctt
     7621 gagtacgatc gtgcagcaat caaaacggtc aaaccaggga ctgtcgtaac aaatgatgca
     7681 acgactactg ttgaaacaac agaagaacca gctgagacag ttgaagtaaa aactgaaaca
     7741 acagaaacgc tggaagagac agaagagaag gaagaaaaat aagtatcaaa gcttatttaa
     7801 agacgaggta gggcagaaag atgtcctacc tcatttttta ttcaaaaaag aaagagataa
     7861 gagcatggga tatattgctc aatattgaat aatcgggtgt gtcatataaa taataataaa
     7921 taactttata tatttttcta tacaaacacc tgtaaataaa gcaattttat atttaaaaat
     7981 aactgtgaaa aaaatcacaa aaaagtgttt acatagaaaa ataaatattg tatgatatac
     8041 atgtgaatta tttaacaaat aaccatgacc cattaggagg ataatgatgg ctaaagtaat
     8101 agaaaaagaa aaaacgaaga caattgacgt acaagcaatg attgatgatt tggcagaaaa
     8161 agcaaatgca gcattgaaag aaatggaaag ctttgatcaa gaaaaagtag accatatcgt
     8221 gcatgaaatg gcaatggcag ctttggatca acatatgcca ttagcgaaga tggctgtaga
     8281 ggaaacaggc cgcggtgttt acgaagataa agcaatcaaa aatatgtatg cgtccgaata
     8341 tatttggcat aatatcaaac atgataaaac agttggtgtg atcaatgaag atgtccaaaa
     8401 agggttgatt gaaattgctg aaccagtcgg tgtggtttgc ggagtaactc caacaacgaa
     8461 tccgacttcc acaacgattt tcaaatcaat gatcgcgttg aaaacaagaa atccaatcgt
     8521 ttttgctttc catccaagtg cccaaaaatc ttctgcagaa gcagcacgag tggtacgtga
     8581 tgctgctatc gctgccggag ctcctgaaaa ttgtatccaa tggatcgaac atccttcgat
     8641 cgaagcgact tctatgctaa tgaaccatcc aggtatcgcg atcgtcttag cgacaggtgg
     8701 agctggaatg gtcaagtctg cttactctac aggaaaacca gctttaggtg taggtccagg
     8761 taacgtacca gcttatattg aaaaaacagc aaaaattaaa cgtgcagtga acgatttgat
     8821 cgtttcgaaa acatttgata atggaatgat ttgtgcttct gaacaagctg tgatcgtgga
     8881 taaagaaatc tatgcagcag taaaagcaga attccaagca caccaagttt atatcgtaaa
     8941 accagatgaa ttgcaaaaat tagaagatgc agtgatgaac gaaggaaaat atgcggtcaa
     9001 tccatcaatc gttggacatt ctgcgatgga aatcgcaaaa ttggcaggaa tcagtgtacc
     9061 aaaaggaacg aaaatgctga ttgctgaatt ggaaggcgta ggcccagatt atccgctatc
     9121 aagagaaaaa ctttctccag ttcttgccat gatcaaagct aacaacacgg accatgcgtt
     9181 tgatttgtgt gaaggtatgt tgaatcttgg aggattagga catacagcag ttatccattc
     9241 agaaaacgaa gagttgcatg tcaaattcgg tcttcgaatg aaagcttgtc gtattttagt
     9301 gaatacacca tctgcagaag gcggcatcgg tgatatctat aacgaaatga ttccgtcatt
     9361 gactttggga tgcggttctt atggtaagaa ctctgtttct cgtaacgtct ctgctgtaaa
     9421 cttaatcaat gtcaaaactg tagcgaaacg gagaaataac atgcaatggt tcaaattacc
     9481 gccaaaaatc ttctttgaaa agaactctct attgtactta gagaaaatgg aaaacgttga
     9541 acgtgtcatg atcgtttgtg accctggtat ggtccaattc ggttactgcg atacagttcg
     9601 tgaagtattg gcacgacgta aaaatgatgt gaagatcgaa gtcttctcag atgttgaacc
     9661 gaacccatcg acaaataccg tatacgcagg aacgaaactg atggcagact tcaagccaga
     9721 tacagtaatc gctcttggag gcggttctgc aatggacgca gctaagggaa tgtggatgtt
     9781 ctatgaacac ccagacacat ctttctttgg tgcaaaacaa aaattcttgg atatccgtaa
     9841 acggacatat aagatcgaca aaccagaaaa aacacaattc gtatgtatcc cgacaacatc
     9901 agggactggt tctgaagtaa cgccatttgc ggtcatcact gacagtgaaa cacatgtgaa
     9961 atatccgtta gcagattatg cattgacgcc agatgtcgca atcgtcgatc ctcaattcgt
    10021 catgtcagtt ccagcatctg tcacagcaga taccgggatg gatgtgttaa cacatgcaat
    10081 cgaatcctat gtttcagtca tggcttcaga ttatacacgt ggattgagcc tacaagcaat
    10141 caagttagtc tttgactatt tagaaaaatc agtaaaaaca cctgatatgg aatcacgtga
    10201 aaaaatgcac aacgcttcta caatggctgg tatggcgttt gctaacgcat tcctaggtat
    10261 ttgtcactca gtcgcacata aaatcggcgg ggaatacggg atccctcatg gacggacaaa
    10321 tgcgattctt ttaccgcata ttatccgcta taatgcaaaa gatccacaaa aacatgcgat
    10381 gttccctaaa tatgactatt tccgtgcaga tacagattac gcagatatcg caaaattctt
    10441 aggtctgaaa ggcgaaacaa cagaggaatt agtcgaagct ttagcaacgg ctgtttatga
    10501 attaggaaaa tctgtcggca tcaacatgag tctaaaagct caaggagtca cacaagaaac
    10561 actagataca accgtagacc gtatggctga attagcttac gaagaccaat gtacgacagc
    10621 taatccgaaa gaaccattga tctctgaatt gaaacagatc atcattgatg cttacaacgg
    10681 ataagcaaaa gaaagcgtag aaaaaagata agaaaataga tgaaaaagaa cttggaaaac
    10741 gttgtttctc caagttcttt ttttaatttc caagtaactg aaagttactt ttgttattta
    10801 acatttaggt caattttaga cagtttttgt tcaaaaagcg atatttatag tggacggtat
    10861 tactgctata ttaaggatat aaaatgaaag cgtttaaaaa ggtggcgtaa agatgattat
    10921 taaagaagag atttttgtac ctaaagaatt agtgaaagaa aaaattgacc tgctcgttga
    10981 aaacctgaca acgatcaaag acgataatgg tgaatttttg ttggactttg atggactgaa
    11041 agtagatgac aaaagctgga cagtgtggaa ttggccacaa ggtgtcggtc tatatggtat
    11101 ttataaaaat taccagatga caaaaaatcc tcgcgcttat caagtggtca atgaatggtt
    11161 tgaggatcgt atggaagaag gcgctccgcc caaaaacgtc aatacaatgg caccgctatt
    11221 gactatggct tacttgtatg aagacacgaa agattcacgc tatttgcctt atttagaaca
    11281 atgggcagaa tgggtcatga atgacatgcc tcggacaaat gaagacgggt tacagcatgc
    11341 cacatatgga ccggaaaata agaatcagtt gtgggacgat acattgatga tgacagtgct
    11401 tcctttggca aaaatcggga aactgttgaa tcgcccagaa tatttagaag aagctcgtta
    11461 ccagtttatg atccatatca aatacttgat ggataaacga acaggattgt ggtatcacgg
    11521 ctggacgttt gaaggaaatc ataactatgc cgaagcattt tgggctcgtg gaaactgctg
    11581 gttgacgatt gctattccag agatcattga aatcttagaa ttatcgaaag aagatgcatt
    11641 gcgcaaatta ttgatcgaaa cacttgaagc acaagtgcgt gcattaaaaa cttatcagtc
    11701 tgaaagcggt ttatggcata cgttgttgga tgatccttct tcttacgtag aatcttctgc
    11761 aactgcagga tttgcttacg gtattttgaa agcggtccat aaacgttatt taccacaaga
    11821 atataaagaa gtcgcttatc gtgctatcca aggattgctt gaacaaatcg atgaaaaagg
    11881 agaagttcaa aacgtttcaa tcgggacagg aatgggggac agtttagatt tttatcggaa
    11941 tatcggaatc acagcaatgc cttatggaca gtcgttaacg gtgctttgtt tgacagaatt
    12001 gctcgtctct tattgttaaa agaaaggaaa cccatatgaa aaaaacatca ctgctgtttg
    12061 cagcaagttc gcttagccta ggtctgctag gtctaagcgg ctgcggaaat aattctagtg
    12121 tggcaactgt cgcagatgca gacgtaaatg agatagttac cttgcgcttt gcttatgcaa
    12181 gcaacagcca gtaattgatg caatgaatga atttgggcgt ttagtaaaag aaaaaacaga
    12241 tggttccgta cagatccagt atttcccaga tggacaactg ggtggagacc gtgaactgat
    12301 cgaattgaca cagtcaggag cagtagattt cacaaaagta agtgcctcag cgttggaaag
    12361 tttctctaaa gattattcga ttttttccgt tccttatcta ttcaatgatg aagaacattt
    12421 ctttaaggtg atggataatg aagaaataat ggagccaatc taccaatcga ccaaaaattt
    12481 aggatttacc ggattgacct attatgattc tggtcagcgc agcttttata tggtagacgg
    12541 tccgatccat acgccggaag atttgaaggg aaagaagatc cgtgtgatgc aaagcgaaac
    12601 cgctatcaaa atggtagagc ttttaggcgg ttcgcccgta cctatgggaa gtgatgaagt
    12661 gtacacgtct cttcaatcca atttgatcaa cggatcagaa aacaatgaat ttgtcttgta
    12721 tacagctgga catggcgggg tagctaaata ctattcctat gatgagcata cacgtgtgcc
    12781 agatatcatc atcatgaatg atgccatcaa agaacagcta actgatgaac aggaaaaagc
    12841 cattgaagaa gcagcgaaag aatcaacggt ttttgaaatt gaagcttttg caaaagcaat
    12901 tgaagaagaa aaagctttag cacaagaaga acatggagtc caattcaatg atgtagataa
    12961 tacaccgttt cgagaggcag ttgacccact tcatgatata ttcaaaaacg atcctaccta
    13021 caaagacctt tatcaaaaga tccaagagca aggagcgtag ctgtaatgaa aatgatttta
    13081 aacaaggtat tagagatcct gggagctgtt ttgcttgttg ggatggtcgc tgttgtttta
    13141 tggcaagtat tttccagaac ggttttagga aatccaaata cggtcacgga agagcttgtt
    13201 cgattcggtc ttgtctggtt tgccatgttg tcttccgcgt atgttgtggg acaaaaagca
    13261 catttagccg taacggtttt aagtgaaaaa ttaactggca aaaaaagtaa aattttagaa
    13321 gttgttgttc aaagtttatt tctggtattt gctgcgatga tcatggtgta tggcggatgg
    13381 aatgctgtca cattgacaat ggggcagatc tcgccttctt taagtattcc tatgggatat
    13441 gtttatctgt cagtacctgt atcgggggta ctcatcatta tctatagcct gatcaatcta
    13501 atcgatacat taagcaacaa gccagcaatt caagaaaaaa tataaaaatg gaggaataaa
    13561 atggcaatag aagccggatt agtgttattt tttgtatttg ttgtgttgct tgtattaggg
    13621 atgccgattg ctataagtat tgcattctca tcgatgatga ctttattgtt agttataccg
    13681 tttgatgttt ctgcttttag ttcagctcaa aaaatggtgg gaagtatcaa tagtttttcg
    13741 ctgatcgcta ttccgttttt cgttctctcg ggcattatca tgaataatgg agggatagct
    13801 aagaaactag tggattttgc gatgttgttc gtcgggcgcg tgccgggggc tttggctcat
    13861 acgaatgtgt tagggaatgc tttatttggt tccatctcta gctcggccat tgccgcttct
    13921 accgcgattg gtggagtgtt gatccctcag caagtggaag aaggatatga ccggaagttt
    13981 gcgacagcgg tcaatatcgc gtcagctccg acaggtatgg tcattcctcc aagtactgct
    14041 tttatcatgt attcacttgt tgctggtggt gcttcgatct ctgctttgtt tatgggaggt
    14101 tatctcgtag gcgctttgtg ggcgctagga atcatgctag tagcattcat cgttgctaaa
    14161 aagaataaat accctgttgt cgaaaaagga cagatggctc atgctggaaa aataataaaa
    14221 gaggcgattc ctagccttct attgattgtc atcattatcg gtggtatctt gacggggata
    14281 tttacagcag tagaagcttc agcgatagct gtcatttaca aatgggttat acgattttag
    14341 aaccaggaag tgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    14401 atgtctattt tgattatgcc aatgaagata cacgtgtgtt ccatatgatg ggcaaaccag
    14461 atgaaacaaa acatttagtc gtagacaatg aacaagccat tatttcgcca agctggtcga
    14521 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    14581 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    14641 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    14701 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    14761 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    14821 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    14881 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    14941 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    15001 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    15061 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    15121 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    15181 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    15241 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    15301 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    15361 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    15421 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacaccgtt tagtggagag
    15481 gttgtgaaat cagcggcttg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    15541 gaaaaaagag gctgggacag aagcgtttaa ctccaagaaa taagaaggaa ttcacgaaaa
    15601 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttgcttccgc
    15661 cgtttatacg tgtttagagc gtgggataaa agtgttcttt acttttgtcc cacgctcttt
    15721 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    15781 ggtccggaaa agatcagtga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    15841 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    15901 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccactgcatt tgcgccgaga
    15961 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    16021 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    16081 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    16141 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    16201 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtc
    16261 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    16321 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttcttgg
    16381 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    16441 tgtcgcataa tcgtataagt atcggctaaa gaagggtctt tcaaggcagc gctgactgaa
    16501 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    16561 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    16621 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    16681 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    16741 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    16801 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaaggatg ccagatttct
    16861 ggtcaacaat tacgattccg caatcgccac cacctgcacc agaagatttt gcggctcctt
    16921 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    16981 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    17041 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctgtttttta
    17101 agaaaagctg ataagccacc attttgtctt ctctcgaacg gtgaacttga tcgaccaaat
    17161 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    17221 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    17281 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    17341 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    17401 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    17461 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    17521 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    17581 catacttttc agtcaaacga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    17641 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    17701 attggatact tccgactttt cgtgcggatt ctacagtgac tgttacgaat tgatcgactg
    17761 cagcgataac tgctggatgt cctgtttcaa caactgcata ttctccggca atatagagtt
    17821 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    17881 gaccagcatg ggcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    17941 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    18001 agtagcatgg aatgcctttt tttctcaatt gccgcaccgc atccatcgct tttaagctgt
    18061 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    18121 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    18181 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    18241 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    18301 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    18361 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    18421 cagacccgcg tcgagcaaat cttgaaagag agagatcgtc taatccaagc ttaagagcag
    18481 tattgcaagc tcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    18541 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    18601 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgtaag gtgccatcta
    18661 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    18721 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    18781 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    18841 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    18901 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    18961 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    19021 aaatcattgc tgattgtcag cttttccaga agtgactgtg attcatccat tgtctgtgcc
    19081 aacgtttctg gtgaattctc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    19141 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    19201 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    19261 ttcaaagaaa agtagtcaaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    19321 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    19381 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    19441 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    19501 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    19561 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    19621 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    19681 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    19741 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    19801 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    19861 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    19921 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttgtt
    19981 cttctttgac tagaaaaaat acaattgaca ctactagata ttgggggtat atttaaaaag
    20041 gttggagtta aacacaatat ttagtgatga agtgagctgg aggtaaatga gcgtgatcgt
    20101 tttagcaggt acaattggtg ccggaaaatc aagtttaaca gaaatgatgg ctgaacactt
    20161 tgatagtcag gcattttatg aatcgattga tgataatgaa gtcttgccct tattttatgc
    20221 aaaccctgaa cagtatgctt ttttgctgca aatttatttt ttgaataaac gttttgcaag
    20281 catcaaacaa gcaatgaaag atgacaataa tgtattggac cgttcgattt atgaagattc
    20341 actgcttttc catctaaatg cagatctagg aagagcaaca gaaacagaag ttcgtgtgta
    20401 tgatgaactg ctggaaaaca tgatggaaga acttccctat gctgcccata aaaaacatcc
    20461 ggatttatta gttcatattc gtgtatcttt tgatacgatg ttagagcgta tcgaaaaacg
    20521 tggtcgttcg tatgaacaat tgtcctttga cccaagtcta tacgattatt acaaagaatt
    20581 gaacagacgt tatgatcaat ggtatgaaga atacaaagaa agtccaaaaa tccaaatcga
    20641 tggagaccgc tataattttg tggaagatcc tcaagcaaaa gaagaagtct tgaaaatgat
    20701 cgaagaaaaa ttagcagaga ttcgccaaac caaagtatcc atttgattta cagttgctca
    20761 aataaagggt aaacctttat ttgagcgact tttttcttta tactggaaac aaatgtcagg
    20821 aggatagagt atgcgggaaa aacactattt taatcaagac cgtaattttt ggatcaatgt
    20881 acagcaaaac gatgtgctag ctgttaaaaa cttaaaagaa gaatatggca ttagtgacga
    20941 gatgctgact tattctctag ataaaaatga acgggcgcgc gtagagtacg attcttttga
    21001 tgaagcgtta ctgcttgtat caaatgttcc gcaccagcaa aaagtcgata atcattatga
    21061 aactagtcct atcgctttta ttttaaaaga agacggtttg tttacattta ccacgccgaa
    21121 taccgagtac gtgattcgac taattcgatc gcttttggaa cggatgccag acatgagtgt
    21181 atacagttta ttgtttcgta cattgttttt gatttctgat tccttttttc ctttaatcga
    21241 ggaagtgaat agtgaacgtc agcggcttaa tctgaaatta agagaaaaaa caacgaacaa
    21301 gaatctgctg caactttcag atttagagat cggtttggtt tacttagtta caggaacaaa
    21361 acaaaatgta gtacttttag aacaaatcaa ggcactggct atttatcgca agttgtcaga
    21421 aaaggaaaaa gaagagttgg acgatgcact gatcgaagca cgacaagcag ttgaaatgac
    21481 gaacttagct tcgcagattt tagaccagct ctctggcact tataataatt tgctgaataa
    21541 caacttgaat gacacgatga aatttttgac ggtctggtcg ctgatcttga ccgttccaac
    21601 tattgtgaca ggattcttcg gaatgaatct ccagttaccc tttacccatt ccgttttcgg
    21661 atggggaatc gccttgatca tcagtttggt cttatctatt tggatgctta ttgcactgtg
    21721 gcggcggatt cgttgatcta gtctttgatc tgcaaaccaa gggcttgggc gatcacaagt
    21781 gcttgctctt gattgacgat tagtcccgcc aaagaatctt gagataaagc gattgttgtg
    21841 aagaaattag tcgtaaagtc taatcccttc agagaagttc gaaaccagtt cgaaccggtt
    21901 aactgattgt cagacaaaaa aaggtttttc caagtgacct cataaaattc gctgtcttct
    21961 aattgacaat gatcgaagga gacagctttc aagtttgtac tactaaagga agccatcgaa
    22021 gcaatacaat cagtgaaagt acagtctcga agataacttt cggcaaaatt cgtacctgtt
    22081 aatttacatt gatgaaacac gacttggtgg aaactgccac caatccactc cagattggaa
    22141 aaatcacatt tttcaaaaat gacattactg cattcaaaat gacgtaaacc tgttttttgc
    22201 atcgtaagtt tttggatatg actctctctt aataccatat ttttggcatc gagatagctt
    22261 tggttacctc cgttgatcag aagaccagag aagatctcct catcttctaa ataaaactct
    22321 ccctttgtaa gaagaggaag agaaggtgga ataggttcga tttttttcat gtgggttcac
    22381 ctcgtttttc tttagtatag caaagaagcg ggaatcactg ctagaaagcc tgctaatcta
    22441 atcattttca gaaaaggaag acaaactgta tgaaaaacat tgacaaaaag attagttttt
    22501 gctatactat aatggttgag aaataaaagc agaagcaccc gcttctcgcc ttagttgata
    22561 atgtcactgg gctagatagt tttcactggt tctattaggt gaagtacgcg cgggttctgt
    22621 aagagaactc gtttttttat tgccgtttat tcggtaagct tttctttctc tcataatatt
    22681 tggaggtgaa tgaccatagc aaaggatatg atggttaacg acggcattcg tgcacgagag
    22741 ttacgattga tcggttcaga tggtgagcaa ttaggagtta agacaaaagc agaagcattg
    22801 aatattgcag aacaagcaaa cttggatctt gtgttagttg cccctggtgc gaaaccacca
    22861 gttgcgcgaa tcatggacta cggtaaatac cgtttcgaac aacaaaagaa agaccgcgaa
    22921 gcgcgtaaaa aacaaaaagt gatcaatgta aaagaagttc gcttaagtcc tacgatcgac
    22981 ttgaatgact tcaatacaaa acttcgtaat gcacgtaagt tcttggaaaa gggcgataaa
    23041 gtgaaagctt ctatccgttt caaaggccgt gccattaccc ataaagaaat tggtcaaaaa
    23101 gtcttgaatc gcttagctga agaaactgcg gatattgcaa cagtggaaca aaaagcgaaa
    23161 atggacggac gcagcatgtt cttgacgctg gcaccgaaaa acgacagtaa gtaatttgaa
    23221 tgactaactg gctgttggac agccgatagt cggataacga aagattttga ggaggaaata
    23281 tagtcatgcc aaaacaaaaa acacaccgcg gatcagcaaa acgtttcaaa cgtactggta
    23341 aaggcggatt gaaacgcttc cgcgcgttta caagtcaccg tttccacggc aaaacaaaaa
    23401 aacaacgccg tcaattgcgt aaagcaagca tggtttctag tggcgacttc aaacgtattc
    23461 gccaacaact agcaaaaatg aaataagaag tacaaataac agaatctgaa gatttatttt
    23521 tattaggagg aattatacat ggcacgtgtt aaaggtggaa cagtaactcg taaacgtcgt
    23581 aaaagagtgc taaaattagc aaaaggttac tacggttcaa aacacacttt atttaaaaca
    23641 gcaaaagaac aagtaatgaa ttcatacaac tacgcatatc gcgatcgtcg tcaaaagaaa
    23701 cgcgacttcc gtaaattgtg gattgctcgt atcaacgcag cagctcgtat gaatggcttg
    23761 agctactcaa aattaatgca cggtttgaaa gttgctgaaa tcgacatcaa ccgtaaaatg
    23821 ttagctgact tggctgttaa cgatgcagca gcatttactg cattggctga ccaagcaaaa
    23881 gaagctttgg ctaaataagc taaacaatta taaagaggaa agaagataac gaaaagttat
    23941 gttctttcct ctttttttat ttacaatcct ccatcaaatg aaacaggaca ataacgtata
    24001 agtctaaaat aacataatta aggtttttta attgaaaact gaacatttat ggtcatcctt
    24061 taatgaaagc gctaactaca taagttagaa tgagtttgac tgatatatta gtttgcttat
    24121 cagaaaaaca aaatggacgg aggaataaca tgagtgatat tattattggt attttgttag
    24181 ttatctcatt ctttttcatg gtctggtact gtgtaaaagg ctacaacttg atggtcggct
    24241 tttgtcatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    24301 aactcggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    24361 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    24421 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    24481 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    24541 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccgat cttgatgtca
    24601 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    24661 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    24721 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    24781 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    24841 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    24901 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    24961 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    25021 cagtttgcga aattatttac agatggcgca gtcgatgttg caccaatggt tggtttcttg
    25081 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    25141 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    25201 ccactaggat ttttccacgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    25261 gtcgtgttag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatt
    25321 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    25381 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    25441 ggtgcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    25501 cgataaaaac gattagataa atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    25561 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    25621 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    25681 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    25741 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    25801 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    25861 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    25921 tcaaaaactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    25981 cagaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    26041 tttatgaagc agcatctgtg aaagcgatcc ctacaacgat ggcttctgac atcacaaaat
    26101 tatatggatt gacaagaaga actcggacag cagcaatcaa cgcatctatt ttaccaaaaa
    26161 tgctagatac ggcaacctcg acagaagact ccgtacgaga agcaggggtc aatgtttctt
    26221 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    26281 ttttaaccat gctttccggt cctgctgcat cagtcatggg ctctttgatg tacttgagag
    26341 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    26401 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    26461 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    26521 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    26581 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    26641 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    26701 cagccaatgt tcttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    26761 cacgaaaagc catacaggca ttagcagact attgtcatac gacggttgaa gacatcgcag
    26821 agcagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    26881 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    26941 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    27001 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    27061 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    27121 aatcaggcgc tacaccagaa tcgatcgaag tacacgtaga aatcgatcca cagacttcaa
    27181 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    27241 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    27301 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    27361 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    27421 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    27481 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    27541 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    27601 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    27661 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    27721 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    27781 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    27841 tttgccgatg taggagaaat ctgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    27901 gagcaaataa acgaacgaat cacttttgta acttatgcag aagatgaagg gatccgattg
    27961 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    28021 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    28081 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    28141 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    28201 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    28261 caagggatct tagaagaaat aaaagaaata gaaaaaagat gtacggagta tgatttagat
    28321 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacggt
    28381 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    28441 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaaag
    28501 gtgttcaaaa gcttgcatct gcggtaataa gaacagccaa gttaaaaaca taagaagcta
    28561 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    28621 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    28681 ctattttgcc gtttatttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    28741 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    28801 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    28861 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    28921 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    28981 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    29041 aaatcaaaaa aagctttttt attttgagcg atcactgcct gatcggtttg ttctagtatt
    29101 ttttctagtt tagcttgatc ttgcttggtc attttcgcac tgcattcttg caggatcggt
    29161 ttttccaact tttcccgcgt ataacgggct aatgaagcag atcggatatc gatttttgaa
    29221 acataagtgc cggactgtgg aatggttttt acaagctctt gattgcgcag ttggatcagt
    29281 gcttctcgaa tcggtgtacg cccgatagct agttgttctt ctaacacttt atcggagatt
    29341 ttacttccag gtgctaactc ggaataaatg atttgtttac gtatagattc ataagcttgc
    29401 tgttgcaaat tattgataac catttaacct tcctttctat gcagatataa tctattataa
    29461 cataaatcgc ttacaaatcg tgtgggcata aaaacacagt ctgcaaaaaa agccctgata
    29521 ggcatgccta ttagagcctc gaaaagaaaa atattgaatc aatctggtcg tacctcttgg
    29581 atcggtttga cacgaccgcc gattctttta gcaaaagctt cggattcttt tttgtctttg
    29641 aaaatgagca gattgtctaa gtttttttcc cgagtgcgac agccagtttt atcgatgtaa
    29701 ccgtgcatta ctttaacgac atacatgggg atcacctgct tttttctttt cattatacga
    29761 actactcgac acaatacaag aaaaatgctt agacggtctt tattaagaat ttacatcatc
    29821 caaagaagcg tacgcttgga ataactgttc taactccgga ttgactttgc tcagcttcac
    29881 taatcgttgc gaatcagaaa gtaaaaaaca gtgtttacta ctgccagtag tttttaattt
    29941 tttgtcttca gttcccacaa tttcgtagct aaaatccaac cgtgttcccg tatacttttg
    30001 gatagttggg tggatgctca ctttttctcc gtaatggatc atttctttat agctgcaatt
    30061 tacttccaga acggggatga tgatcccaga ttcttcgatt tttttatagg gaaaccctag
    30121 atgtaccaat aaggctaccc gagcctcttc aaaccagcgg atataattgc tgtgatgaat
    30181 aatccccatt tgatctgttt cataataaaa aggttctcgc acataacctg taaatttctc
    30241 catgactcat gcctcgtttt ccattgattt tttacaaaaa taattcatcc acttcggaag
    30301 tgcttcgctg atttgtgtcg gcaaaacaat atattgttct tttgccagct ggtctccaat
    30361 gaaactatga agataaacag ctgctgcaat cgtttggtca ttttgaggaa actgggctaa
    30421 aaatcctgtg atcatcccag ctaaagtgtc acccatgccg cctgttgcca tagcagcaga
    30481 acctaaagga ttggtgtaga agtgctggtg accataaatt tttgtctcat gacttttcaa
    30541 aacgagcaca gcaccgattt cctgttgctt ctttttgttt tctttatccc gttgttcttg
    30601 tatcggtaga gaactcaacc gttgccactc catttgatga ggtgtaagta cagtttgttc
    30661 gggatagggt agcaaaagat gattagcaac aagtaaactt aaagcagagc catcaatcac
    30721 cagccattgt tcttttgatt gtttttctag tacttgtttg aaacgttcca aactcttaga
    30781 agaagtaccc aatccgggac caatcaagag tacatctgct tgctttatta cggaaagaaa
    30841 ctggtcagta tccgtccaat ctacaatcat tgcttctggc agatgactgt gaagagcact
    30901 ccgatttttt tcatcagtta ctacagtcgt gagacccgct ccactgtgta cggcagctaa
    30961 agcactcata atgattgctc cgccatattg ttcattgccg ccaatcaaaa cgatacgtcc
    31021 aaatgttcct ttatgtgaaa tttttggacg aggtgtgatg actcttttca ctagttgttc
    31081 gtttatcagc atcgaaaaac ctccttttac tcattatagc gtatattttt tttagagaaa
    31141 aacagataag aaaaggaatt gtcagatttt ttgaactatt tttttctgta atttgtggta
    31201 tcatgaacac gaagacttaa ataagtggag gattaacttt atgacaattg attggcaaaa
    31261 agaagtagaa gcacgtaaag aagacttgct tgaagacttg aaaaatcttt tacgtgtcaa
    31321 cagcgagcgc gatgattcaa aagtaacacc agatgcacca tttggacctg gacctcgcga
    31381 cgcattgaaa catatgttag cttatggcga acgtgatgga tttaaagtaa aaaatgtcga
    31441 taactatgca gggcatattg atcttggcga aggagacgaa acgctaggga tatttggaca
    31501 catggatgtc gttcctgcag gagatggctg ggacacagat ccttatgaac cagtaatcaa
    31561 ggatggaaag atctttgcac gcggatcaag cgatgacaaa ggtccaagta tggcagctta
    31621 ctatgcgatg aagatcatta aagaacttga cttgaaacta tcaaaaaaag ttcgcttcgt
    31681 agtcggcagc gatgaagaaa gcggctgggg cgatatggct tattatttcg aacatgaaga
    31741 agaaccagat tttggtttct caccagatgc tgaattccca atcatcaatg gtgaaaaagg
    31801 aaatgtttct ttagctttac gcttcaaagg cgacaatgca ggagattatg tcttgaaatc
    31861 ttttgtttcc ggacttcgcg aaaatatggt gccaggaaca gcaactgcag cacttcaagt
    31921 accaagtgca gatgcagcta tcgcgatgga agaagcattt taccaattca tcgaagcaaa
    31981 tccagtaagc ggaacgattg aagcggacaa tacgtatgta aaaatcgaat tagttggtaa
    32041 aggcgcacat ggtgcaagcc cacaatctgg tatcaatgca ggttctttct tggcattgtt
    32101 cttagataac tatgaattcc taggatctgc taaacaattt atccatgtag cagctgctta
    32161 tgtccatgaa gatttttatg gagaaaaact aggagtcgct tatgaagatg aaaaaatggg
    32221 caaattgaca atgaatgctg gactatttgc ttttgaagaa aatggtacag aggaagcgaa
    32281 cttcatcaat atgaatttcc gttttccaaa aggtgtaaca gtagacggat tgcaaagtga
    32341 catcgaacaa acagtggggc aagaaggcgc aacagttact cgaggtgctc gcgtaatgga
    32401 accacattac gtaccaatgg atgatccatt ggtggctaca ttattgcaag tctatgaaga
    32461 ccacactgga gaaaaaggct acgaacaaat catcggtggc ggaacttacg gacgtttgtt
    32521 gaaacgtggc gttgcttatg gagcgatgtt cccaggatat actgatacaa tgcatcaagc
    32581 aaacgaattt atgagtcttg atgacttgtt cagagcaaca gcaatctatg cagatgccat
    32641 ctatcgtttg gcgaaataaa aatactaaaa aactccggct atctctgaca gctggagttt
    32701 ttatgtttaa aaatgaatta gtacatcggt attcttaaaa gtaatttagt tcgtcttttg
    32761 atttctcagg agggatcaaa aaggcgaaag cactaagtat agcaaaactt gtgatgattt
    32821 gcgtacgata cgtaaaccaa taatgaatct gtgagtgatt agctaaaata ttgtaccaaa
    32881 tatacggcgt tacagcagct aaaacaaaca aaactagaag ttggaacgga cgccagctat
    32941 ttcgtttacg ataagcaaaa tagagaaaaa caagacaagt aatcaatagc aataatattg
    33001 ctacttttgg atacatcaat ctaatattgc ttttcagcat ctctaatcga tgcaacgggt
    33061 atttgtcgtt tccttccgtt cgaaagagga tttggttgat tgcatctttt acaatgtttt
    33121 tgttcaatat gatcgatgat aggatccatt tagccaccca tgtcaaacca tagcctaatc
    33181 cccaaaagat accggtaaaa acaaaactgc ctacttgttt gctcaatgaa ctgcgtttat
    33241 ccattaaata cttatttgtt acataataaa taatgatcac aggtatcccc caagagatga
    33301 ccggtgttgt caacaagtca aaaaagttag ctaaagaacc aatgacaaag aaatacaaga
    33361 ataattgttg gttggtgttg gagagttgtg gttttgttaa aaatagtaat acagacaata
    33421 aagtcaaaat ccaaatattt gaaaattgca tactgaagaa aaaggttgca gcatttccta
    33481 tagcaagcga aatcaacaag gctgtcgtta aatagatgtc gctacacttg gttaaaaagt
    33541 agctcgtcaa tccaatcagc agaaaaagaa tggctgcgta aatcattcga atactcccca
    33601 aactcatccc tagcagtaaa ggtcgtaaaa aaagctgata accatgccaa taacggggat
    33661 aatccgccat agacatcgcg ttctccaagg agttcaattc aggatctgct tttgtttttc
    33721 gtatcatcaa atgatcagta aaattatcta accgagtgcc tagcatattt ccttgattga
    33781 tagaaggata cattccttct ttttcaacca tctgtagaga tttttctgca ttcgattcaa
    33841 tagagtgctg cggaatgaaa aaagtaattg tcagtagtac gcaatagcta gcgatcaaga
    33901 gaacaaaagc aaaaaatatc tttttaaata gtttcatgag tatctcctat atctgttttc
    33961 attttttctc ttttatctag taaaaaagga gagaggatat aaacaggtag acctaatgct
    34021 aaaacaaaca cataccgtaa actaaaagcc acaggagtag caatcataat agtagcaaaa
    34081 acaagcatac cgggaagaaa aaggagtaaa taccgatatt ttttcttaaa gattgctaaa
    34141 agtgcactgc cgatagctaa ccacagtaat gtgccggaac caaagaaatc acgagcatcg
    34201 atgatttttt tcattcctga caatccagta agatgttcaa tcaaatctac ttgcttcatc
    34261 ccataattat tcgtgtttac acgagtatct aaaaagccgt aactattttt tgtaccaggt
    34321 acccagaacc cgaacgtttc taaaatataa gcatctgtat agatttttat attacttggt
    34381 aaatttcttg cccatagtga tagaaattct tttttatgtg tattcaaaaa ctcattgtta
    34441 aaatttttat gccacttgat tgagtctgca agactaggag aatacgcttc ataatctttt
    34501 atcgggagta gctgattcat gaatgcttta tctttcttag acaagtcacc atccataaca
    34561 atagttctag aaatttgctg caaaggaaca cctaattgtt cagcagtttc tgtaggaata
    34621 gcataacgag ccatcaacgg gtggatgagt agtccagcaa tcactgtata acccagcacc
    34681 acttgaaaga atgcttgata ccttttttgt ttcaaaataa tcaagccgca aatcaaacct
    34741 gtgccggtta ctacataaat cccattattt cttagatagg tggtcagtaa agcaaggatg
    34801 attacgtaaa tctgattgag aatcgttggc ttttctcgtt gaaaaataaa gtcaaaaacc
    34861 gctaaggaaa ataaaaagca agcgatagag aacaaagtat ctttttgcat gttcaaggcg
    34921 tagattggaa aaaccggtgc aaatgcaaaa tagcataaac taatgagtac cggaaaaaaa
    34981 tggatgtttc tttttaacag ccagcaaaga gaataactta tcgctgaagc tgttatcaat
    35041 gtttgaaaaa tcgaaaataa aaatacaccg tgattgatcg tatcagttgg taaatcatga
    35101 acaaatagct tgaccagtaa ggtgaataag actggatgat gattgcttat aggaacatca
    35161 cccatagatt gggcgaccga acttaacgaa tcaggcaaaa ccactccagg atacaatgcc
    35221 aacagataag gaagccaaca cagaactaaa aagacagtaa agaataaaaa atattttctt
    35281 gaagagaaag cctgtgtgtt ttgagcagta aaaaatgttt ccagttttgg cattgataaa
    35341 taaatcgatt gtaaaaataa aaaagaatac acaaaaatgg agaaataaac aagaaagtaa
    35401 aaaatacttc catcagcaat cgttgtcttt gtatagtttg ctgagacata ctgaaattgt
    35461 atctgtctgc caatagaaag tgtaagagca aaagctgcag aaaaaaacaa tcgggcaata
    35521 gctgcaactt tgttttttat tgaaaacaac tctattccat attgcttaaa agcaagtagc
    35581 aaaaccatgg ctaaaccaat gattactgtt ggattcaaag ttcctagacc ataagaagta
    35641 aaaaaagcaa aacctgacgc aaataaagtt gcaaaaaaag taggaaatag attctccttt
    35701 ttcttatgca taaaaaaggc ctcctacttc atttctttat tttgatattc gtggtagaca
    35761 tggtataaat tcaattcata ttctttcttg gcatttgtga cgaccgtatc caaaatcaac
    35821 cctgttacta atgaaagaag ggctaaagtc atcaatccag tacttaaaat cgcagaaggg
    35881 atgcgtgtaa taaagcttgt cagcatatat tcacgaatca caggaatccc catgaccaat
    35941 ccaaataaaa agaagaagat ggtccagatc ccaaagaaaa gcaaaggttt ataatctttg
    36001 cacattttga tgatcatcat gatcactttg aatccgtcag agaatgtatt caattttgat
    36061 tcgctacctt caggacgatc gcgataatcg attggaatct caacgaactt gaatttttta
    36121 tctaaagcat gaatcgtcaa ttctgtttcg atttgaaaac cagaactcat aatagggaag
    36181 cttttgacaa aaattcgatt gaatcctcga tagccggtca tgacatcgcg aatttttgtt
    36241 ttatataagt aagtaattgt atttttaacc agattattcc caaaatcatg gaaaggacgc
    36301 ttattttcat caaaataggt tccatttgat agacgatcgc caatgaccat atctgcttcg
    36361 ccagaacgta atttctcaag caaaccatgt gcagcttctg caggataagt atcatcacca
    36421 tctaccatca aataataatc ggcatcaata tcaaaaaaca tttgacggat tacatttcct
    36481 tttccttgac gtggttcttt ctttacgatt gctccacctt gaacggccaa ttcgtatgtt
    36541 cgatcggtcg aattattatc atagacataa atatctgctt ctggtaattc ccttttaaaa
    36601 tcttcaataa cagttgaaat tgtcgcctct tcgttataac aaggaatgag cacggcaatt
    36661 ttttcacgtg attccatttg tcactctcct tatataataa aactaatctt atttcaagaa
    36721 taccgtataa taactataaa tactagctat tccaagagga aatagcccta tttttataaa
    36781 aattacccac tataaaagaa gtataggata cctctctttt gaatagtggg tgcgtattcg
    36841 ttctctcact tttttgacgt attaatctgt tgcacctttt tttcttgaaa tttctaatac
    36901 ggttcctgta tgagcatctg ctaaaaattc ataataaaca gtttcgccat cttctattcg
    36961 agaaagacct ccccgataag cactcgaccg aacggcgaat ttcctaatag gttccttttc
    37021 aaaagagatc caagaacctt cgattgcacc ttcttttaga aaagatgact tgatattttc
    37081 aagtacttgg tctgctgaca atactttttt gcgatgatac caaatcgttg aagctacccc
    37141 gctcaataat cctagaccga ttccaactgc taacccgcct ttaaaatagc ttagttcgct
    37201 ttcttcatac atgtggacat acctccttct tctcacttgt tactccttgt gcttatttta
    37261 ccacactctc atattttctt tgaaataaat aaccgctacc agaaaaaata agctataata
    37321 aatacgatcg gtctgcagaa aaaatcatat tttatccgca gatcaatata agtctgagag
    37381 gagtttagtc tgaaatttag acgaatagca tatggaagaa aaaacatttc aacgaatcaa
    37441 agagttaaca gaattacaag gaacaagcgg ttttgaacaa gatgttcgcg cttatatgga
    37501 aagtcatatg gaaccgctgg tagatgagtt acagttagat ggtttgggcg gcatttttgg
    37561 tctgcgccat catgaagaag cggatgcacc ccgtgtaatg gtcgcagcac atatggatga
    37621 agtcggattc atgctgacac aaatccaaga aaacgggctt tttaaagtcg tacctctagg
    37681 cggctggaat ccttacgttg tttctgcaca gcgttttaca cttaaaacct ctactggtaa
    37741 gaattatcca tgtatttctt cttccgttcc cccgcattta ttgcgaggaa caagcggaca
    37801 aaaatcagta gaagtaaccg atattttgtt cgatgctggg tttgaatcaa gagaagaggc
    37861 aatgagttac ggtgtccttc caggagacac aatcgttcct tacgctgaaa cgatcaaaac
    37921 agccaacgga aagaatatca tcagcaaatc atgggacaac cgctatggct gtacaatggt
    37981 attagaagct ttagaagcgt tgcaaaatga aacattaggt catacattga ttgcaggcgc
    38041 gaatgtccag gaagaagtag gcttgcgtgg ttctaaagct tctgtcaata aattcaagcc
    38101 agatctgttc tttgcagtag actgctctgc agcagatgat acagtgacga aaaatggcac
    38161 attcggacat ttaggagaag gtacattgat gcgtatccaa gatccaggtt tgatcatgct
    38221 tcctcgtttg cgcgagtact tgctggatat cgctgaaaca aacaatatcc cttatcaata
    38281 ctttgtttca aaaggcggta cagatgcagg tgctgctcat acacaaaacg aaggaatccc
    38341 aagtacagtg attggcgtag tgggacgtta tatccatacg catcaaacga tgttcagtat
    38401 tcgcgatttt gaagctgcac gagaaatgtt gattcaaaca ctgaaaggtt tggataaatc
    38461 aacagtgaat acgatcgtat acggaaaata atgcgatagt gaaactataa aatctggcaa
    38521 aagattgctt ttgccagatt ttttttataa aaagaggatc aatgtttgtt agttcgaaag
    38581 aaaggtgtat aatttaattg aaaaatacat aaacagaaag tagaggacaa agaatgatta
    38641 tcccaaatag tttagaagaa ttagcaggct acgtagaaac tggaaagagt gtatttttct
    38701 ttactgccag ctggtgcgga gactgccgtt ttatcaaacc gcaaatgcct gaaattgaaa
    38761 atgacttttc tgattggcaa tttattgaag tagaccgtga caagtacata gatgtagccg
    38821 ctgaatggaa catttttggt atcccaagtt ttgtcgtgat ccaagacgga aaagaattag
    38881 gtcgtctagt gaataaagat cgtaaaacaa aacaggaaat cgaatcgttc ctagaaagtg
    38941 taacaaaagg ctgacatctg ttaggagggg tcaagatgaa tcaagaatat aagaacattt
    39001 tagtaggtat cgacggtagt gaacaagcac ttgctgcttt caaaaaagcg gtagaagtgg
    39061 ctcgccgtaa taatgggaaa gtatatgtag caaacgtaat cgatcagcaa ttttataact
    39121 ttatgggcta tgcacctatt gatcaaaatc tagtcgatca gcaaactgaa acagccaagc
    39181 aaatgatcga agaatgtaaa gaatatggga aatctgttga ttacacaaat atagaaggaa
    39241 ttattgcata tggttctgtt cgtgaatcca tggcagtcaa attgccaaaa aaatatgcaa
    39301 tcgatctaat catggttggg cagtcaggtc taaatgcagt cgaacgcttt atgacaggaa
    39361 gtgtagccag ctacgtgata cgtcattcac cttgtgatgt cttgatcgtt tctgacgaag
    39421 aagaacagcc aagtaattaa gcaagtggaa cttgtacgac ctttttaatc aattaactaa
    39481 aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg aataaatggt
    39541 gttccagaag aggcttcttc ggaaataaag catgaaaaaa atctcatgca gtgaatgcaa
    39601 ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga tttttgctta
    39661 taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata aaggaacaga
    39721 aaacaccgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag gacaagttgt
    39781 tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg gccaagtaag
    39841 cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag gattcgaaga
    39901 acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa catgcgtccc
    39961 acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg gtacagtatt
    40021 gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg ttgcaaaacc
    40081 aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag gggtagatag
    40141 ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag caaaaaaagg
    40201 aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat aaagaggttg
    40261 tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat tttgttttaa
    40321 tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc cttcatagta
    40381 agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa gttctacacc
    40441 agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca atccagcttt
    40501 ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta cagatgaagg
    40561 aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga ccattgtgat
    40621 acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga tattcactac
    40681 atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag tagattcaga
    40741 agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat taactaaagg
    40801 accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga tattgactgt
    40861 ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga ttcctgaagt
    40921 gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag gctcaccaac
    40981 cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg aattgatctt
    41041 caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta ccttcgtacc
    41101 gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat tcgtgactac
    41161 ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat aagcttccaa
    41221 attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc caaaaccgct
    41281 tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa ctttatctac
    41341 cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg tttcaccggc
    41401 agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca tcgctgcata
    41461 aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca gacctaactt
    41521 acgccagagg ctattatttt tatttttttt catctttggt gtcacatttt ttctatccat
    41581 gtgttcctcc tccaattaca ttcatttatc tactgttagt atactcttat ttgttgactt
    41641 tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaacc attgttttca
    41701 gatgaaaata tttgatttgc ttttttccaa agaaactgtg taaaactacg cggataggat
    41761 tggaaaaata agggataaaa catatccaca gcctgtgtat aaagtggata aattcttata
    41821 aaacgtatgt ttgcctaatg aatgtgatga aataaggtaa aataacactg ttttctgtgg
    41881 ataaacctgt ggatgttgtg cataactgtt ggggaaatct ttttaacaaa aatagccaaa
    41941 ataaacatat agacgaaaaa attgattata ataaacaaag tgagcatgaa gaccaaagga
    42001 gagaaaacat gaatatcaaa attatttcag taggaaaatt aaaagaaaaa tacttgatcc
    42061 aaggtatcaa tgagtatgtc aaacggctga atgcctatgc aaaaatcgaa ttgatcgaag
    42121 ttcctgacga aaaagccccg gagaatttaa gtgaagcgca aatgagacaa gtaaaagaaa
    42181 aagaaggaga acggatctta gcgaaaatca aagaacaaga atatgtctat gccttagcaa
    42241 ttgaagggaa aaatcccaca agcgaatctt ttgctaaaca aatcgaccaa ttaggtatcc
    42301 aaggaaaaag ccaccttgtt tttgttatcg gcggctcttt aggactcagc gaagccgtca
    42361 tgaaaagaag caatgctcag atctcttttg gcaaaatgac gtatccacat caattgatgc
    42421 gtctgatcct cgtcgagcaa atctaccgtg cctttcggat caatgcgggg gctccatacc
    42481 acaaataatg atatttttta agagaaaaat tatcc
//
LOCUS       DAIGQM010000018        40774 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.018, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000018 DAIGQM010000000
VERSION     DAIGQM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.018"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            1..1284
                     /locus_tag="NOA48_000953"
                     /pseudo
     CDS             1..1284
                     /locus_tag="NOA48_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(1985..2185)
                     /locus_tag="NOA48_000954"
     CDS             complement(1985..2185)
                     /locus_tag="NOA48_000954"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789236.1"
                     /translation="MAEMHDHLLHSICERTGLSEEEVNQKLMEISEAMNKGVDFSMNQ
                     LDDFLAQHMKDALASDAADSVE"
     gene            complement(2535..2882)
                     /locus_tag="NOA48_000955"
     CDS             complement(2535..2882)
                     /locus_tag="NOA48_000955"
                     /inference="COORDINATES: protein motif:HMM:NF019886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0789237.1"
                     /translation="MDHLHDHDAENRLESNYARYLGGIEQTIEDSYTQDCMMSYTPDI
                     VEKIAPTDFKKMERKRLQEEIQKLTFNQRKVIEHYYFLNKNQQQIARDLRMSHAEITK
                     TLKRAFAVMKEVY"
     gene            complement(3277..3654)
                     /locus_tag="NOA48_000956"
     CDS             complement(3277..3654)
                     /locus_tag="NOA48_000956"
                     /inference="COORDINATES: protein motif:HMM:NF025104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789238.1"
                     /translation="MFFLAFLYLYIANVKYFSKWPLLLFWIISCVLLLVKNAVFQFLL
                     KKIGSKSHTRVLVVENGNLAKEYGLAMLSDPDADANIIGYVKDRKKEDILLEEPGFAN
                     YGDGLAKLKYFGRISDVQDVIVK"
     gene            complement(3678..4001)
                     /locus_tag="NOA48_000957"
     CDS             complement(3678..4001)
                     /locus_tag="NOA48_000957"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789239.1"
                     /translation="MIDRRDDSDRCWSIRYYYKGRINEIIKERFWNTVFDCIGDAASI
                     FVAYLLAMFICYHVLEAAPGINMLSVPYLMMAALYSILIADFLRIFRATNKTYFRKYQ
                     NGFLK"
     gene            complement(4063..4539)
                     /locus_tag="NOA48_000958"
     CDS             complement(4063..4539)
                     /locus_tag="NOA48_000958"
                     /inference="COORDINATES: protein motif:HMM:TIGR01670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789240.1"
                     /translation="MSQIKFLVMDVDGTLTDGKIYMGECGEIMKAFNIKDGCAIHDIV
                     RAHNIEPIIITGRRSKILENRCKELGINILYQGIDNKIEKLLEITSDLSTVAYIGDDI
                     NDLSCMHPVKSAGGIVACPHDAVKKVLEISDFIAEHDGGNGAVREFVEWLVDTQNN"
     gene            complement(4556..4921)
                     /locus_tag="NOA48_000959"
     CDS             complement(4556..4921)
                     /locus_tag="NOA48_000959"
                     /inference="COORDINATES: protein motif:HMM:TIGR00022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCI0789241.1"
                     /translation="MELEEGRYDLSNGIYLNVESYDIYRFEERMYESHLKYLDIQCIL
                     LGCEYIVVESISNLQIEVDYSADKDIVFYSNSIVGNCVLLEGGKLLLLTPEDAHMPCI
                     RVNESAKVKKAVFKISINY"
     gene            complement(5004..5969)
                     /locus_tag="NOA48_000960"
     CDS             complement(5004..5969)
                     /locus_tag="NOA48_000960"
                     /inference="COORDINATES: protein motif:HMM:TIGR00393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HCI0789242.1"
                     /translation="MDKIIEAKRVFDIEIEALKRTRDCLGKTFVRILDAIVNCEGKVI
                     ITGMGKPGHIAAKLAATFASLGTPAFRLHPAEAMHGDLGMVSEKDIVIAISYSGESDE
                     IVKILPNIKMIGATLIGITGNSKSTLATASDIVQILPEFEEACYLGLAPTSSATSVLC
                     YGDALAVVASGIYGFKDSDFGKFHPAGSLGKKLILKVSDLMSHGNEIPMVNSGTLLMD
                     AISVMSNKGLGIVSVIDQDGTLKGIITDGDLRRIIERKVDIYSVEIDDVMIANPKVFT
                     KDKLAVDALRFLKANSINILPIIDDEGMLVGTITWQQIVKAGIVA"
     gene            complement(6078..6854)
                     /gene="kdsA"
                     /locus_tag="NOA48_000961"
     CDS             complement(6078..6854)
                     /gene="kdsA"
                     /locus_tag="NOA48_000961"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010388312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HCI0789243.1"
                     /translation="MNRLMLIAGPCVIESEENVMLIAKTIKEITEKLDIDYYFKASFD
                     KANRTSITSYRGPGIEEGLKILKKVKETYGLKICTDIHEPWQAEKAAEVCDILQIPAF
                     LCRQTDLLVAAAKTGKIINVKKAQFLAPWDMKNVINKLVEAGNSNIMLCERGTSFGYN
                     TLVVDMTSIVEMKKFGYPVVMDATHSVQKPGGKGDVTGGNRNNVEPLAKAAVATGADA
                     LFFEVHPDPDNALSDGPNMVLLDEFEGLLERVLKVYNAVR"
     gene            complement(6856..7593)
                     /gene="kdsB"
                     /locus_tag="NOA48_000962"
     CDS             complement(6856..7593)
                     /gene="kdsB"
                     /locus_tag="NOA48_000962"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: protein motif:HMM:NF003952.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HCI0789244.1"
                     /translation="MKTIAIIPSRYGSSRFPGKPLAMISSKPMIQWVYENVSKAAMLD
                     AVYVATDDKRIFDCVESFGGMALMTSDKHTCGTDRLAECAEILQLRDEDLVLNIQGDE
                     PLIKAEMIADLYSCFDNDEVYMGTLKKHIEVQEELDNPNVVKVINDVNDYAIYFSRFC
                     VPYERDGKNSLHFKHIGVYGYKTWFLKKYSTMPKTPLEVSESLEQLRVLESGFKIRVK
                     ETKYQTVGVDTPEQIQQVEDELRKEGL"
     gene            complement(7590..9017)
                     /locus_tag="NOA48_000963"
     CDS             complement(7590..9017)
                     /locus_tag="NOA48_000963"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024832.1,HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HCI0789245.1"
                     /translation="MNRLIKNYAYNLCYQILVMILPIITTPYVSRVLKAEGVGEFNYS
                     YAIVSVAVIIAQLGTNMYGQREIAYVQNDKIRRSGVFWSIFVIRIISSFIVFPVYILI
                     SATLHSYTVLLISMSVYLVANLFDVSWFFQGMEDFKKTAIRSMVVKLIGLVLIFLLVK
                     NENDVVLYSVILAGTELLGNALLCCHIPKYVRRISIHDISITPHIRPILGLFLPTAAV
                     YIYTYVNKIILGIFSTDVQVGLYSQPEKIVKLLMTVITSLGAVMLPHIAVAVKENNID
                     RIRKEVLNAVSFVFCIGAPMVVGAIIIANTFIPWFLGDGYAKSVSLFQLLSPLILIIG
                     FASVVGQAVLIPMKRQRVYTFSIMTGAVINLVVNLALIPHLEAIGAAIGTIFAELTVT
                     AIQFYEVRNCIELKMASIITNVKNYLIGALIMGGVGGYVSSKLPNSVISTFITVILCI
                     LLYSILLICMKDKLLMDYLKRRKNR"
     gene            complement(9019..10332)
                     /locus_tag="NOA48_000964"
     CDS             complement(9019..10332)
                     /locus_tag="NOA48_000964"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HCI0789246.1"
                     /translation="MIYQLLIVEFILILIMYILSNRCFISPAFIAIALFFLATCCVVY
                     NIEFWNVQYSKKTLWFITTGFLAMCIPEMYILFLDYLSKKRVDNYHQNQYKIEYVQIY
                     PSRQLNLIFALLSVVFFGVLLVEILRKGDYSTLGLYAIGAAKSDETQNSVIARFGISL
                     ITGLNLAYLYVFINNVIRCKERVLSNIKYLFPTLMYILCMFISGNRVFLVKLFAIVFL
                     IYIVMKSDVSPRGRVPVMQVVRKTLFVAVAILAVFYALRGITKVNSTAATREFSDYIT
                     YYIGSPVYMLDKYLQRYSPELNWGAKSLTSLVEMFGIEPEFKNAYIHVGGDSNFAGNE
                     FSWFQRPYSDFGWLGMLVFTFIVFWIFSWNIHIRINKEKNRRRRKYYILITAYFFYIP
                     VMSFYYCQMCFAFSITNIFSVVVACLLVREFTKRQDEIIFKIKEE"
     gene            complement(10333..11478)
                     /locus_tag="NOA48_000965"
     CDS             complement(10333..11478)
                     /locus_tag="NOA48_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HCI0789247.1"
                     /translation="MKKARVLAFYLPQFHPVRENDIMWGKGFTEWTNVAKAKPLFKNH
                     YQPQIPADLGFYDLRISEVRKQQAEMAKKYGVEGFCYWHYWFGNGKRILELPFNEVLQ
                     SGEPDFPFCLGWANHSWSNKTWQKSKHFTKDVVFLEQTYPGDEDYILHFKSILPALKD
                     DRYIKVDGKPLFLVFAPDSIPDSAHFISLWNKLAKENGFEGIYFVARVTSVDNKFDLS
                     SMTDVAVHNRFQRFLDMGYDAINSDMQRYAELKISGYWKRGIKSIMRKTVGNFSANLY
                     PYDKIMENFYCEEEKRECVHPQLIPRLDRTPRSGKDARVYVDSTPEKFGNAIDRALSY
                     VQDKEPEHRILFLQAWNEWGEGNYMEPDLVFGCEYLEILRKKILGEE"
     gene            complement(11475..12281)
                     /locus_tag="NOA48_000966"
     CDS             complement(11475..12281)
                     /locus_tag="NOA48_000966"
                     /inference="COORDINATES: protein motif:HMM:NF014075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HCI0789248.1"
                     /translation="MVNIKIRKVIHRIPPILKLMRFVVDVQNKYFYDKFCKNTDNIQR
                     IEKLRNKFLGETCFIVGNGPSLTMEDLELIKDKDCFAANLIFKIFDKTQWRPKYYFIQ
                     DRYADTGNELDDIDLEYMFIGDYYWRVRGMHNPNAICIHSEQSVGGKNIKFSEDISKS
                     IVSHETVTYSMIQAAVYMGYKKIYLLGMDHSYALTYNADGTVSEDKTIRSHFFEDKNA
                     NEVIASIVGMNQAYIRAREFCESNNIKIYNATRGGKLNWFDRITLEEAVK"
     gene            complement(12340..12528)
                     /locus_tag="NOA48_000967"
     CDS             complement(12340..12528)
                     /locus_tag="NOA48_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016396235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HCI0789249.1"
                     /translation="MVVKGTSDDFYHANDEGGLAWNDPEIGIEWPQVLGEYKGNASAE
                     GYIFEDDTPLNISEKGQR"
     gene            complement(12876..13010)
                     /locus_tag="NOA48_000968"
     CDS             complement(12876..13010)
                     /locus_tag="NOA48_000968"
                     /inference="COORDINATES: protein motif:HMM:NF013621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HCI0789250.1"
                     /translation="MKEKVIEYTTGVYDMFHIGHLNVMRNAKAQCDFLIVGVSTDEPV
                     "
     gene            complement(13351..14484)
                     /locus_tag="NOA48_000969"
     CDS             complement(13351..14484)
                     /locus_tag="NOA48_000969"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0789251.1"
                     /translation="MRQKIRVLHIAQAAGGVDCYIRMLLKYLDKEKFENILICSQDFC
                     ETDYANLVLSFKQIKLTREIDLNDLKAIVIIRKLIKKYNPDIVYAHSSKAGAITRVAK
                     IGLKNYCVYNPHGWAFNMRCSVKKKMLYTAIEKIAALFCDKIICISDAEKQSALKKRI
                     CCEDKLQVIFNGVDIEAYRNKAHGEVKRESLNIPQDAFVVGMVGRISPQKAPEIFIKM
                     ARLVKNKIPEAHFIIVGNGEQKALIEKYAAEHGFLESLHITGWVNNSISYIELFDVAC
                     LLSRWEGFGLALPEYMMVGKPIIATNIDAIPNLISNGKNGLLVPVDDETAACEAVFKI
                     FSDKAMAARLTSEATSVVLEKYNSKRVASEHAVLFEMLVKKRG"
     gene            complement(14396..14948)
                     /locus_tag="NOA48_000970"
                     /pseudo
     CDS             complement(14396..14948)
                     /locus_tag="NOA48_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
     gene            complement(15417..16106)
                     /locus_tag="NOA48_000971"
     CDS             complement(15417..16106)
                     /locus_tag="NOA48_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0789252.1"
                     /translation="MESEDLLSRISKVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYAAYRIRKEEPGSPIFFSHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTQIGKIIRAKSIDELPQLWNVLKGDMSLVGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSGRNDVSFHAMVDLDLEYITNQSLLNDFKLIIKT
                     IWIVIKPNGAY"
     gene            complement(16160..16924)
                     /locus_tag="NOA48_000972"
     CDS             complement(16160..16924)
                     /locus_tag="NOA48_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCI0789253.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIVMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIQRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(16952..17650)
                     /locus_tag="NOA48_000973"
     CDS             complement(16952..17650)
                     /locus_tag="NOA48_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCI0789254.1"
                     /translation="MARTQKQKATPTHAVSLITLTNPSSPIAEQYRTIRTNIQFASTT
                     GQQIKTIVVTSSGPGEGKSTTASNIAVVFAKSGQRVLLVDADLRKPVIYKTFQLNNAS
                     GLSTALSSSGSVADVIQRAPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPIVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDDGYYYGN"
     gene            complement(17663..18442)
                     /locus_tag="NOA48_000974"
     CDS             complement(17663..18442)
                     /locus_tag="NOA48_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCI0789255.1"
                     /translation="MEETISLEEIFETLRKHLITIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVQERLKTEDNVKMTP
                     EQIKDAISINQSENSQMFSIQAISTSAMTAQQIANTTSQVFQENAKDVMNVDKISIVS
                     GAVANTTPISPNNKLNLVIGLMLGMMVGVVLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSEKELKAGIRKKGLAPTRPKVTNDKTASSRRSRSRV"
     gene            complement(18458..19402)
                     /locus_tag="NOA48_000975"
     CDS             complement(18458..19402)
                     /locus_tag="NOA48_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0789256.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLNKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGVQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSILNALESNMKTDMSFDEMKKIALDYREAFDTIKQD
                     QMQGEGFMQDDISYQKVNDNELDRVKKELKEQMNLENK"
     gene            complement(19439..20215)
                     /locus_tag="NOA48_000976"
     CDS             complement(19439..20215)
                     /locus_tag="NOA48_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789257.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKIRAAYATKAQTVAQQMGYSNIS"
     gene            complement(20600..22675)
                     /locus_tag="NOA48_000977"
     CDS             complement(20600..22675)
                     /locus_tag="NOA48_000977"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCI0789258.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22677..23594)
                     /gene="glyQ"
                     /locus_tag="NOA48_000978"
     CDS             complement(22677..23594)
                     /gene="glyQ"
                     /locus_tag="NOA48_000978"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCI0789259.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(23980..24792)
                     /gene="recO"
                     /locus_tag="NOA48_000979"
     CDS             complement(23980..24792)
                     /gene="recO"
                     /locus_tag="NOA48_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCI0789260.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(24935..25834)
                     /gene="era"
                     /locus_tag="NOA48_000980"
     CDS             complement(24935..25834)
                     /gene="era"
                     /locus_tag="NOA48_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCI0789261.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25849..26244)
                     /locus_tag="NOA48_000981"
     CDS             complement(25849..26244)
                     /locus_tag="NOA48_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCI0789262.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(26228..26704)
                     /gene="ybeY"
                     /locus_tag="NOA48_000982"
     CDS             complement(26228..26704)
                     /gene="ybeY"
                     /locus_tag="NOA48_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCI0789263.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26721..28913)
                     /locus_tag="NOA48_000983"
     CDS             complement(26721..28913)
                     /locus_tag="NOA48_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCI0789264.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28937..29908)
                     /locus_tag="NOA48_000984"
     CDS             complement(28937..29908)
                     /locus_tag="NOA48_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCI0789265.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30614..31993
                     /gene="brnQ"
                     /locus_tag="NOA48_000985"
     CDS             30614..31993
                     /gene="brnQ"
                     /locus_tag="NOA48_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0789266.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(32149..32595)
                     /locus_tag="NOA48_000986"
     CDS             complement(32149..32595)
                     /locus_tag="NOA48_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCI0789267.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(32622..32798)
                     /locus_tag="NOA48_000987"
     CDS             complement(32622..32798)
                     /locus_tag="NOA48_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCI0789268.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(32960..33388)
                     /locus_tag="NOA48_000988"
     CDS             complement(32960..33388)
                     /locus_tag="NOA48_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0789269.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            33480..34340
                     /locus_tag="NOA48_000989"
     CDS             33480..34340
                     /locus_tag="NOA48_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCI0789270.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(34434..34784)
                     /locus_tag="NOA48_000990"
     CDS             complement(34434..34784)
                     /locus_tag="NOA48_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0789271.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(34800..36527)
                     /locus_tag="NOA48_000991"
     CDS             complement(34800..36527)
                     /locus_tag="NOA48_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI0789272.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(36741..37667)
                     /gene="trxB"
                     /locus_tag="NOA48_000992"
     CDS             complement(36741..37667)
                     /gene="trxB"
                     /locus_tag="NOA48_000992"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCI0789273.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(37812..39248)
                     /locus_tag="NOA48_000993"
     CDS             complement(37812..39248)
                     /locus_tag="NOA48_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0789274.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     ENEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(39245..40648)
                     /locus_tag="NOA48_000994"
     CDS             complement(39245..40648)
                     /locus_tag="NOA48_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0789275.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
BASE COUNT        11716 a         8853 c         6740 g        13465 t
ORIGIN      
        1 gaagaagaca aaatttcgct agatgcactt gttcctaaaa atcatttagt ccgtaaaatt
       61 gacaagttat tgtcatttga ttttatttat ctcattgttg aatcaactta ttcgaccatc
      121 ggtcgaccta gcgttgatcc tgtcgtctta gtaaaattag tattcattca atatttattt
      181 gggattcgtt cgatgcgtca gaccattaaa taagtttaaa caaacctagc ttatcgttgg
      241 tttcttgggc ttagtttaat tgataaagtt cctcattttt caacttttgg taaaaactat
      301 gcacggcgtt tcagagaaac cgatttgttt gaacagatat ttatcattat tctggaacaa
      361 gcagttgttg ctagatttat tcatgaagaa attttgtata tggattcaac tcatattaaa
      421 gagaatgcga aaaaacgtat ttttacaaaa gatatggcac ataaagaagc cattttatac
      481 caaaaacgat tggaagaaga aatcaatgag gcaagaattg ccgaaggcaa acgccatttt
      541 ggttcaatca ttcgtcagga ggtggtcgaa aggaaattta gcgtcgcaga tccagaaatt
      601 ggttattatg taaaaacaga acgagaaaaa cagtttgctt attcttctca tactgtttgt
      661 gatgaaaatg gttttgtatt agatgtcatg attacgccta gaaatctaca ttacagccga
      721 atgctcgtgc cacaaatcga acgtgttaaa tcacgttatg gtgtagctgc tgatgctgcg
      781 tacaaaacac cttggaacgc caagtattta atcgaccgaa aactacgacc cacttttcct
      841 tatactcgac ccaaaggaaa caaagaacgt tttaaaaaga aagattttga ttatgatccc
      901 tattataact ggtacctatg cccgaatgat caaacacttc agtttcgcac aactactcga
      961 gatggctata aaaaatatgt atctaaatct tttatttgtg aaagttgtcc attattgaaa
     1021 aattatacag aaagccagaa acaccaaaaa gaaatacatc gacatatttg tgaagattac
     1081 ttagatgaag cagaacattt acgccatacg gtgtacaatc gcgaaaaata taaaaaaaga
     1141 aacgattgaa cgcatttttg cagacgcaaa ggaaaagcat ggagtgcgct acaccaagta
     1201 tcgaggcttg gaaaaaatca ggtgcatacg atgcttgttt ttgtcgcaat gaatctgaaa
     1261 aaattagcca cttggcagtg ggagcatatg tctttatatc ttttattata caaaaataga
     1321 caaaagtatc agtctacact cttagtcaag aggaaactga tgcttttatc tacagtctga
     1381 gagagtggga caatagtcct ttctccaaaa gaaaacaagt ccgactttga tagttaattt
     1441 taaaatcgga cttgtttttt cttctttacg tcttttcctc tccatgtatt tccctaattt
     1501 tcttaaattt aacgccatga gtgccaagcc aatgttaatc ttggctcctt gtttccctcg
     1561 taagtggaaa tccgtttccg atagatcgaa ccttcttttt cctctaaaaa ctttttttac
     1621 attctgcttt gaaataacgc catgtattat tcactaaaat ttgtcggttt cgctcacttt
     1681 ttgctttcgt acattgacta cgaacagggc agcaccacca taagccgcct gccagttacc
     1741 tctcactctt accgggtctt tcagaacacc cggatgctct aacacatcac tcggctaggc
     1801 tccgttattg aagaagaaag ccccatatct ttccatggca tcctcggcca gcttaagaag
     1861 ctcctccatc tgttcggaga ccttcctcac atatatgggc aaaggccatg aagacctcca
     1921 ccagactgtt catgaccttc ttcagtgctg cgatcatctg ctctctcttc tccatggctt
     1981 acacctactc gacagaatca gcggcatcag aggcaagagc atccttcatg tgctgtgcca
     2041 ggaagtcatc cagctggttc atagaaaaat cgacaccctt gttcatggcc tcgctgattt
     2101 ccatcagctt ctggttcacc tcttcctcag acaggccggt gcgctcacag atggaatgga
     2161 gcagatgatc gtgcatctct gccatcttct ggtccatgtc gaatttttcg tggcagcaat
     2221 ctctgcgcca tgccttcgga aatacggctt ccccccctca tcagactgtg tgtttggttc
     2281 cagctctttc ttccgggatt cttcgctctc ggaaatcggt ctgtacagtg aacacacata
     2341 aatattcttc ctatgactgg tatcactcat ggcttgtctc ctttatttgt tttgtcgagt
     2401 cctacctcaa aggaggtctg gccagcatat aggtgttcat ctgactgtcc ctttcaaaat
     2461 tagtgtcctc atctatgatt tcgggcgttt tataactcct ccggacaaaa tttttgaaaa
     2521 aatttgtcga gggcttaata cacctctttc ataactgcaa acgcacgctt caaggtcttg
     2581 gtgatttctg catgcgacat gcgcagatcc ctcgcaatct gctgctggtt cttgttcagg
     2641 aagtaataat gctcgatgac ctttctctga ttaaaggtta gcttctggat ctcttcttgc
     2701 agacgcttac gctccatctt cttaaaatca gtcggagcaa tcttctccac aatgtcagga
     2761 gtataggaca tcatgcagtc ctgtgtgtag ctgtcctcga tggtctgctc tatgcctccg
     2821 aggtatcttg catagttgga ttccagacgg ttctctgcat catggtcatg tagatggtcc
     2881 actgatagtc catatactcc tcaaccagga tgaagctatt cttatcggcg aaccgataca
     2941 acattccatt catgcggtca gctgtgaaga tggagtacat atcattgcga atatagagga
     3001 taaagtcgtt gcgatacacg gtcaacagag aatcgtccat ctagaactga gccacactca
     3061 cttggcacca tattatcact cagctaacgg aagccgggct gctttacgcc tttggtgctg
     3121 tccttgattt ccttccatat actgcttgcc gagattgatg attcttctga catcgatcaa
     3181 agtaacaggt aatttagaat cttccacaaa cctgattatc tcctctacta ctttcggctc
     3241 aatatcttct aatgcgatca cgattttata tacctgctac ttcacaataa catcctgaac
     3301 atcagatatt cgtccaaaat actttaattt cgccaatcca tccccataat tagcaaatcc
     3361 tggttcttca agtagaatat cctctttctt tcgatctttc acatatccaa taatatttgc
     3421 atctgcgtct ggatctgata acatggccaa accatattct ttagccaggt ttccattttc
     3481 cacaaccaaa actcgagtat gggacttgct gcctatcttt ttcagtaaaa actgaaatac
     3541 agcattcttg acgagcaaca aaacgcacga tatgatccaa aataaaagca atggccattt
     3601 ggaaaagtat ttcacattag cgatatataa gtataagaaa gcaaggaaga acaaacttcc
     3661 aataccggtt aacgatacta ttttaaaaat ccgttttgat actttctgaa ataggtctta
     3721 ttcgttgcac gaaaaatcct caaaaaatct gcaatcaaaa tactatatag cgcagccatc
     3781 atcaaatacg gaactgacaa catattgatc ccgggagcag cttctaaaac gtggtaacaa
     3841 ataaacatgg ccaatagata ggctacaaaa atagatgctg catctccaat acagtcaaaa
     3901 actgtgttcc aaaatcgttc cttgataatt tcattgattc tccccttata ataatatcga
     3961 atgctccaac atcggtcaga atcatctctt ctgtctatca ttcgccacgt agaagttgtt
     4021 ggaaaagagt gacaaccgtt caagacgaac ggctatattg tattaattat tctgtgtatc
     4081 aactaaccac tcaacaaatt cacgcactgc accattacca ccatcatgtt cagcgataaa
     4141 atctgaaatt tctagaacct ttttaactgc atcgtgcgga caggccacaa taccacctgc
     4201 acttttaaca ggatgcatac aagataaatc gtttatatcg tctccaatat atgcaacagt
     4261 acttagatca ctagtaatct caagcagttt ctctatttta ttgtctattc cctgataaag
     4321 aatgttgata ccaagttcct tacatctatt ttctaatatt ttggaacgac gaccagtgat
     4381 aataataggc tcaatattat gggctcttac aatatcgtga atagcgcaac catctttaat
     4441 attgaacgcc ttcataattt ccccacactc acccatatat atctttccgt ctgttagagt
     4501 accatcaaca tccataacca gaaatttaat ttggctcata cactttcccc ccctttcaat
     4561 aattgataga aatcttaaat acagctttct ttactttagc tgattcattc actcttatgc
     4621 aaggcatatg agcatcctca ggagttagta gcagcagctt ccctccttct aagagtacac
     4681 aattgccaac tattgaatta ctgtaaaaca caatatcctt gtcagctgaa taatctactt
     4741 caatctgtaa attagatata gattctacta caatatactc gcatcctaag agaatacatt
     4801 gaatgtctaa atatttcaag tgagattcgt acattctttc ttcaaatcta tatatatcat
     4861 aggactcaac attcagataa attccattgg aaagatcata tcgaccttct tctaattcca
     4921 acaaggaatt ttttataaga aaatatagac ttctggaaat tcaatttcca tttttttaga
     4981 cttaactttt tcatttatct cctttatgca acaataccag cttttacaat ttgctgccat
     5041 gtaatggtac caacaagcat accttcatca tcgattatag gaagaatgtt aatactatta
     5101 gcctttaaaa atctcaatgc atcgacagct aatttatctt tagtaaatac tttgggatta
     5161 gcaatcatca catcatcaat ttctacagaa tagatatcta cttttctctc aataattcgt
     5221 cttaaatctc catcagtaat aatgcctttg agagttccat cctgatcaat gactgaaact
     5281 atacccaacc ctttattcga cataacagaa atagcatcca ttaacaatgt tcccgaattg
     5341 accattggaa tctcattgcc gtgggacatt agatcagaca ctttaagtat taattttttg
     5401 cccaatgaac ctgcgggatg aaactttcca aaatcagaat ctttaaatcc ataaataccg
     5461 ctagcaacaa cagctaatgc atcgccgtaa cacaacacac ttgtagcact agaagttgga
     5521 gccaatccca aatagcaagc ttcctcaaac tccggtaata tctggacaat atcagatgcg
     5581 gtagcaagcg tagattttga attgcctgtt attccaatta aagtagcccc aatcatttta
     5641 atattaggaa gaattttaac aatttcatcg gattcgccgc tatagctgat agcaattaca
     5701 atatcctttt ctgaaaccat acctaaatct ccatgcatcg cttcagcagg atgaagtctg
     5761 aatgctggtg ttcctaagct tgcaaatgtc gctgccagct tagcagcgat atgacctggc
     5821 tttcccatac cagtgataat gacttttcct tcgcaattaa caattgcatc aagaatacga
     5881 acgaaagtct tcccaagaca atctctcgtt ctttttaagg cctcaatttc aatatcaaaa
     5941 actcttttgg cctctattat cttatccatt ttatttacct cttcagtttt taatagcagc
     6001 tggaggtctt tcacatgttg taacacagta caaaatgtga aagacttacc atacatttct
     6061 atgcaatgca agaaaaatta tctaacggca ttgtatactt ttagtacacg ctctaataac
     6121 ccctcaaatt catccaagag aaccatattc ggaccatcag acaaggcatt gtcaggatca
     6181 ggatgtactt caaagaacaa agcatctgcg cctgttgcaa cagccgcctt cgcaagaggc
     6241 tcaacgttat ttctattacc tcctgtaaca tctccttttc caccaggctt ctgaacacta
     6301 tgcgtagcat ccataacaac agggtaacca aacttcttca tctcaacaat agatgtcatg
     6361 tcaacaacca atgtattata tccaaaagaa gtgccacgtt cgcaaagcat aatgttacta
     6421 ttacctgcct ccacaagttt attaataaca tttttcatat cccacggtgc gagaaactgt
     6481 gcttttttta cgttaattat tttgcctgtt tttgctgctg ccactagtaa atcagtctgt
     6541 ctacacagga atgcaggaat ctgaagtata tcgcatacct ctgcagcctt ttctgcttgc
     6601 caaggttcat ggatatctgt acaaattttc aatccataag tttccttaac tttcttaagg
     6661 attttcaaac cctcttcaat accaggacct ctgtaagagg taatactagt tctgttagct
     6721 ttgtcgaaag aagccttaaa ataataatca atatcgagct tctccgtaat ctccttaata
     6781 gtcttagcta ttaacattac attttcttcg gactcaataa cgcatggtcc tgcaattaac
     6841 ataagtctat tcatcttata gaccttcctt tcttaattca tcttctacct gctgtatctg
     6901 ctccggcgta tccaccccca cggtttgata tttagtttcc tttactcgaa tcttaaatcc
     6961 actctccaaa actcgaagtt gttcgagaga ttcagatact tcaagaggcg ttttgggcat
     7021 tgtactgtat ttcttcaaaa accatgtttt atacccataa acaccaatat gtttaaaatg
     7081 cagagaattt tttccatctc tttcgtatgg aacacaaaaa cgtgaaaaat atatcgcata
     7141 atcattgacg tcattgatta ctttaacaac atttggattg tcaagttcct cctgaacttc
     7201 aatatgtttt ttcaaggttc ccatataaac ttcatcgtta tcaaagcaag aatacaaatc
     7261 tgctatcatc tctgccttga taaggggctc gtctccttgg atattaagaa ctaagtcttc
     7321 atcccggagt tgaaggatct ctgcgcactc agcaagacga tctgtgccgc aagtatgttt
     7381 atcagaagtc atcaaagcca ttccaccaaa gctttcaaca cagtcaaaaa ttctcttatc
     7441 gtctgttgca acatatactg catctagcat agctgcctta gaaacatttt cataaaccca
     7501 ctgaatcatg ggtttactag aaatcatagc aagcggcttc cctggaaacc tacttgatcc
     7561 atatcgagat ggaataatag ctattgtctt catcggttct ttctcctttt aagataatcc
     7621 attaacaact tatctttcat acatattagt aaaatactat atagtaaaat acacaaaatt
     7681 actgtaatga acgttgatat tactgaattt gggagcttac tactgacata tcctccgacg
     7741 cctcccataa tcagtgcacc tatcaaatag ttttttacat tcgtaataat tgatgccatt
     7801 tttaattcta tacagtttct tacttcataa aactgaattg cagtaactgt aagttcagca
     7861 aatattgtac ctattgcagc gcctatagct tccaaatgtg gtattaaagc caaattgaca
     7921 acgagattaa tcacagcgcc cgtcataata gagaaggtat acaccctttg tcttttcatg
     7981 ggaatcaaaa cagcttgacc aaccacacta gcaaatccaa ttatcaaaat caatggtgat
     8041 agtaactgaa ataaggaaac tgacttagcg tatccgtctc caagaaacca cggtataaaa
     8101 gtatttgcga ttataatcgc accaactacc attggggcgc ctatgcaaaa cacaaatgat
     8161 actgcattca atacttcttt tctaattcta tcaatattgt tttctttaac cgctactgcg
     8221 atatgtggca acataactgc accaagagat gtaatgactg tcatcaacag cttcactatt
     8281 ttttcaggct gcgagtatag cccaacttgg acatccgtag aaaatattcc taatataatc
     8341 ttattaacat acgtatagat atatactgcc gctgttggaa gaaataatcc taatattggt
     8401 cgaatatggg gtgttatcga tatatcatga atacttattc ttctaacata ttttggaata
     8461 tgacaacata ataatgcatt ccccaacagc tcagttccag ccaatataac tgagtacaat
     8521 actacatcat tttcattttt caccaataag aatatcaaaa caagaccaat taacttaacc
     8581 accatacttc tgattgcagt ttttttgaaa tcttccatcc cttggaaaaa ccaactgaca
     8641 tcaaaaagat ttgcaactaa ataaacagac atacttatta gtaaaacagt gtatgaatga
     8701 agagtagccg aaataagaat atatacagga aaaacgataa acgaagaaat aatacggata
     8761 acaaagatgc tccaaaacac tccacttctt ctgatcttat cattctgaac ataagcaatc
     8821 tcacgttgtc catacatgtt cgtacctaat tgagcaatta ttaccgctac cgatacaatg
     8881 gcgtacgaat aattaaactc cccaactccc tccgctttca atactctaga tacgtatgga
     8941 gtcgtaataa taggcagtat cataaccaaa atttggtaac aaagattata ggcataattt
     9001 ttgatcaacc tattcatatt actcctcctt tatcttaaat ataatttcat cctgcctttt
     9061 cgtaaattct cgtactaaaa ggcaagcaac cacaacagaa aatatatttg ttatagaaaa
     9121 cgcgaaacac atctggcaat agtagaaact catcactggt atgtaaaaga agtatgccgt
     9181 aattagtata tagtatttcc ttcttcttct gtttttttcc ttattaatgc gaatatgaat
     9241 attccaagaa aaaatccaaa aaacaataaa agtaaacacc agcataccta accaaccaaa
     9301 atcagagtaa ggtcgttgaa accacgaaaa ttcattcccc gcaaagttac tatctccacc
     9361 aacatggata tatgcgtttt taaattctgg ttctatacca aacatctcta ccaatgaggt
     9421 aagacttttt gccccccaat tcaattctgg agaatatctc tggagatatt tatccagcat
     9481 atatactggg cttccgatat aataagtaat atagtctgaa aactctcttg ttgccgcagt
     9541 cgagttaact tttgtaatac ctcttaatgc ataaaataca gccaaaatcg ctactgcaac
     9601 gaataaagtt tttcgcacaa cttgcataac aggaactcgt ccacgaggcg atacatctga
     9661 cttcattact atgtatatca aaaatactat agcaaaaagc ttaactaaaa acacacggtt
     9721 accggatata aacatacata aaatatacat taatgttgga aacaagtatt ttatatttga
     9781 taaaacacgt tctttgcatc taattacatt attgataaat acatacaaat atgcaaggtt
     9841 taatcctgta attaaactga tgccaaatct tgcaataact gagttctgcg tttcatctga
     9901 cttagctgct ccaattgcat ataatcctaa agtgctataa tcgccttttc ttaatatttc
     9961 taccaaaaga acaccaaaga acacaacaga taatagtgca aaaattaaat ttaattgtct
    10021 gctagggtaa atttgtacat attcaatctt atattgattt tgatggtaat tatccactct
    10081 tttttttgat aaatagtcta agaataatat atacatttct ggtatacaca tagctaagaa
    10141 ccccgtcgta ataaaccaga gcgtcttctt gctatattgc acattccaaa attcgatatt
    10201 ataaaccaca cagcatgtcg ccaaaaaaaa caatgcaatc gcgataaatg ctggtgatat
    10261 aaaacatcga ttagacaaaa tatacattat taaaattagt ataaattcaa caatcaataa
    10321 ttgataaatc atttattctt ctcctaatat tttctttcgg agaatctcca aatattcgca
    10381 tccgaaaacc aaatctggct ccatataatt tccttctccc cactcattcc aagcctgaag
    10441 aaatagtatc cgatgctctg gttccttgtc ttgaacatac gaaagtgctc ggtctattgc
    10501 atttccaaat ttttctggag tactatcaac atacactctt gcatctttac cagatcgtgg
    10561 ggttcgatct aatcttggaa tcaactgagg atgtacgcac tctctctttt cttcttcaca
    10621 ataaaaattc tccattatct tatcatatgg atagagattt gctgaaaaat taccaactgt
    10681 ctttcgcatt atgctcttaa tacctctttt ccagtatcct gaaattttta attcggcata
    10741 tctctgcata tcagaattta ttgcgtcata tcccatatca aggaaacgct gaaatctatt
    10801 atgcactgct acatctgtca tagatgacaa atcgaactta ttatcaacag atgttactct
    10861 agccacaaaa tagatacctt caaatccatt ctccttagca agtttattcc atagtgaaat
    10921 aaaatgagca gaatctggaa tagaatctgg agcaaaaacc aagaataaag gtttaccatc
    10981 aacttttata tatctatcat ccttcaatgc cggaagaata gatttaaagt gaagtatata
    11041 gtcttcatca ccaggatatg tttgttccaa aaacacaaca tcctttgtga aatgctttga
    11101 cttttgccaa gttttatttg accatgaatg attagcccaa ccgagacaaa aaggaaagtc
    11161 aggttctccg ctctgtaaca cctcattaaa tggaagttct agaattctct taccattgcc
    11221 aaaccaataa tgccaatagc aaaaaccctc aaccccatat ttcttagcca tctcagcctg
    11281 ttgttttctt acttccgaga ttcttaaatc atagaaacct aaatctgcag gaatctgggg
    11341 ttgataatga ttcttgaata gaggtttagc tttagcaaca ttagtccatt cagtaaagcc
    11401 ttttccccac attatatcgt tttcacgaac aggatgaaat tgtggcaaat aaaatgccag
    11461 tacccttgct tttttcattt aactgcctcc tctaaagtaa tacgatcaaa ccaattcagt
    11521 tttccgccac gagttgcgtt atatattttt atgttattac tttcgcaaaa ctctcttgct
    11581 cttatatatg cctgattcat tccaacaata cttgctatta cttcatttgc atttttgtct
    11641 tcaaaaaaat gacttctaat ggtcttatct tcagacactg ttccatcagc attataagtc
    11701 agtgcataac tatgatccat accaagaaga tatatttttt tatatcccat ataaacagca
    11761 gcttgaatca tcgaataagt aactgtttca tgcgatacaa tggatttact gatatcctca
    11821 ctaaacttaa tatttttgcc accaacagat tgctctgagt gaatacatat agcatttgga
    11881 ttatgcattc ctctaactct ccaataataa tccccaatga acatgtattc taagtcaata
    11941 tcatctaatt cgttaccagt atctgcatat ctatcctgga taaaataata tttaggtctc
    12001 cactgggttt tatcaaaaat cttaaaaata agattagcag caaaacaatc cttatccttt
    12061 attaattcca aatcctccat tgtgagactt ggaccattac ctacaataaa acaggtctca
    12121 cctaaaaatt tatttctcag tttctcaatt ctttgaatat tatctgtatt cttgcagaac
    12181 ttatcgtaga agtatttgtt ttgaacatca accacaaatc tcattagctt tagaataggc
    12241 ggaattctat gaatcacctt tctaattttt atatttacca tatttactcc ttccgaatta
    12301 caatatcaac caaaaattcg ttatctaatt aaatgtttac tatctctggc ctttctcact
    12361 aatattcaat ggagtgtcat cttcgaagat atacccttca gctgatgcat tacctttata
    12421 ttcaccaagt acctgtggcc attcaatacc aatctcagga tcattccaag ccaagccgcc
    12481 ctcgtcattt gcgtgataga aatcatcact agtacctttc acaacgatat tcctttcttt
    12541 attaaacttt tatcaactac gataattcaa cttttgatcg agtcctcatc aatgatactc
    12601 ttaattacat gagtcaactg agtgctggaa ataccatctg tatggggaag ataaacaaat
    12661 tcaacaccgg ttcccataaa ctgttcttca tatttttcct actgaggatt gcctttctaa
    12721 tcagaaccca cgaacatttt gttaaattta tatttctccc atgccgcata cttatcctta
    12781 tcattttgag ggacaaccat atcgacatac tttattgaat ttacaatttc ggctcgttct
    12841 acatacggaa taacaggtgt cttattttta tcttactaaa ccggttcatc tgtactaaca
    12901 ccgacaatca aaaaatcaca ttgtgctttt gcatttcgca taacattcaa atgcccaata
    12961 tgaaacatgt catatacacc cgtggtgtat tctataactt tttctttcat aaatatctcc
    13021 tttaactgtg tatttcagag taaaatagga atctttctca tcaatctgca tcacactcta
    13081 catgtccaaa taacatagac cgaaaagtca agaaagataa ttttccagtc tgtgatgaac
    13141 cttctctctt ctacatactt cacatagagt tccattcatt cttcgaaaga taaatcattt
    13201 cgacgcgtaa caatcattac catcgaacaa aaacgttgaa ccacatacaa caggcacatt
    13261 cctgcggtaa tttctttaat gttttttctc ctgagtcttc acttaccccg atatagttaa
    13321 tgcgactcaa aaaatttctt gctttcatcg ttaacctctc tttttaacta acatttcaaa
    13381 caataccgca tgttctgaag ctaccctttt ggaattatac ttttcaagca ctaccgatgt
    13441 agcttcggaa gttagccttg cagccattgc tttatccgaa aaaatcttaa aaactgcttc
    13501 gcaagcagcc gtctcatcat caacgggcac caacaatcca ttttttccat tgctaatcaa
    13561 attgggaatt gcatcaatat tggtggcaat gataggtttt cccaccatca tgtactcagg
    13621 cagagccaaa ccaaatcctt cccaacggct taataaacat gcaacatcaa atagttcaat
    13681 atagcttatc gaattattta cccagcctgt aatatgcaga ctttccaaaa aaccatgttc
    13741 tgctgcatat ttctcgataa gtgctttttg ctctccatta ccaacaataa tgaaatgggc
    13801 ctctggtatt ttatttttta ccaatctagc cattttaatg aatatttctg gagccttctg
    13861 cggactaatt cttccaacca tacctacaac aaacgcatct tgtggtatat tcaaactttc
    13921 tctttttacc tctccatgag ctttatttct atatgcctca atgtctacgc cattaaaaat
    13981 gacctgcaac ttatcttcgc aacaaattct ctttttcagt gctgattgtt tctcggcatc
    14041 tgatatacag ataattttat cgcaaaacag agcagctatt ttttctatag cagtgtatag
    14101 cattttcttc ttaactgagc acctcatgtt gaatgcccat ccatgtggat tgtatacgca
    14161 atagttcttc aaaccaattt tagcaacacg tgtaatggct cctgctttac tcgaatgtgc
    14221 atacacaata tccggattat atttctttat cagctttcta ataattacga ttgcttttag
    14281 gtcattgaga tcaatttctc tagtcaattt aatttgctta aatgagagca caagatttgc
    14341 ataatccgtc tcgcaaaaat cttgcgagca aatcaatatg ttttcaaact tttccttatc
    14401 caaatacttt aaaagcatgc gaatataaca atctacgcca cctgcagctt gggcaatgtg
    14461 taaaactctt attttttgac gcatttctgt cctccatttt acttatcata acaaacagta
    14521 tatctcgaat taccagaaaa ataatcttcc aatcagcaaa gaaaactctc ttatactact
    14581 tcacattgat ctccatccat tctttaaagg aaagttcatt tcaattcaga gcaatctgcc
    14641 aataatagct aagatcaggc tgtacataca attgctgtct ttcatagcct ccatactgct
    14701 tcatctttct cagcaatcca gatttgggac ccacgatatt catatcttcc ttgaaaatat
    14761 tccaaatctg aggagattca tcatccacga acacgaaacg aaacttatag aacttgaaca
    14821 atttaccatt tcttccaact ctatcttgtg cgaaaacagg agtccgccgg atcatcaaac
    14881 acaataacta acgctgtaat cagtatcaca ggacacaaat agcaagtgtt aaaatggaaa
    14941 atatgaatac ttctccaata tacccggact agataactcc cttttgttca taatccctca
    15001 tactcatcag attcaccaaa ctttaccgtt tatttttttc aatagttcac caaatgactc
    15061 catctaacaa ggtcaaatat aaaaaattaa cgcattttca ttatctttta ggcatttatt
    15121 aatggagata tttagtgttt ttataacata ataaatgctc aatgagagcc tatgttgggt
    15181 acatcaatat taaagtattc agcactaata tgtttaagat cgatattata tatttcataa
    15241 ttttgaaaat tttctttcat ataggaaaca tgatactgaa ttgctttagt cacctttctt
    15301 tttttagatt ttctacaagt gattcaaaac ttccataatt acagttatta cttttgaaac
    15361 gataatatga acatgtgtaa tcttttttat caacaatcta tcaattctat cccttactaa
    15421 tatgccccat ttggttttat aacgatccaa attgtcttga taattagttt aaaatcattc
    15481 aatagacttt gattagttat atattctaaa tctaaatcaa ccattgcatg aaaactaaca
    15541 tcatttctac cactaacttg ccacaaacct gaacatccag gttttacata caagcgttga
    15601 agatcatatc tcgtgtactc agctacttcc ctttccaaag gtggacgtgg gccaactaga
    15661 ctcatatctc cttttaaaac attccatagc tgtggcaatt catcaatgct tttagcgcgg
    15721 ataattttac ctatttgggt gacacgggga tcttctttca tcttgaacat tgcgccttct
    15781 atttcatttt gatcaagtaa ctcttccaat ttttcttcag catctaaaca catcgaacgg
    15841 aatttataca ttttgaatgt ttttccattt ttaccaacac gtgtatggct aaaaaatatc
    15901 ggactccctg gctcttcttt tctgattcga taagctgcat agaacatcaa aggagaagct
    15961 aaaatcaaac caatgatgct tcctacaata tcaatcattc ttttaaaaaa taaatagata
    16021 tatcgttttt caactttttc tttatccaac caaacttgat taggatgtac tttactaata
    16081 cgagataata aatcttcact ttccatactt tcagtccctt tcgctctcta ttcatttcct
    16141 ttttatctac gaataaaaac taaaataaac caaacttctt cttttttacc tcttcatata
    16201 ttggataact gatctcatcc ccgttgatca gatcctttgc gacttgcttc atctgtacta
    16261 ctttttcctt accaaagtcc ttggcaatct gctcatagca ctcttttaag taaaaggtgc
    16321 gcttagagac cccatgggca tcagaagcag ccatctgcac gagattatgt ttgaccatcg
    16381 ttttggctgt tttctggata tctttgccaa ataccccaac ataacttggc gcagtgagtt
    16441 gcgccaaaca tcccatatct aggaacggaa gcaaatgatt cgggtcttcg cgaaaatgcg
    16501 cgttacgttc tggatggacg atcactggtg tctttcctag ttctaacaac tcaaaaaaaa
    16561 gctgctctgc atataacggc acttccagtg tcggaaattc gatcagaaga tatgtatcat
    16621 ctaaatctgt aaataaaatt tcatctcgct ggatgtcttc aatgagcgtt ccggtaatac
    16681 gtacttcttg tccttccaat aacgtcaaag gcaattgtct tttctctaat tctgcttgta
    16741 acgaagcgac tagagaaatg acttgtgatt tttcattgct gtattttcca ttattgtggt
    16801 gtggcgtgca taaaatatgc gtgatgcctt gctgaatcgc tttttcagcc attacgatac
    16861 ttgcctctag gttttccgcc ccatcatcga ttcctggtag gatatggcaa tgtagatcga
    16921 tcatttctct tgcctcctct cttcttattt cttaatttcc gtagtaataa ccatcgtctt
    16981 tgctgtgttc tgctccgttg tatacaacac ctaggactcg tgcttgtacc atctccaaca
    17041 gctcttttgc tttagtcaag gattctttac gtgacgtatt ttcacgtacc accaataagg
    17101 tgccatccgt ttttgaagac atgatctgtg catctgttac ggctactatt ggtggcatat
    17161 caaaaattac cacgtcaaat aactgtcttg cttctgctag gatctgatcc attcttggcg
    17221 aacttaacaa ttctgatgga ttgggtggct taggtccact aggcaaaatc gacaagttct
    17281 cgactggcgc tcgttggatc acatctgcta cacttcctga tgaactaagt gctgtactta
    17341 atccactggc attgttcagc tgaaatgtct tatagatgac gggtttacgt aaatctgcat
    17401 cgactagtag aactcgttga ccagatttag caaaaacgac tgcaatgttt gatgcagtgg
    17461 tagattttcc ttctccagga cctgatgatg tcacgacaat cgttttgatt tgctgaccag
    17521 ttgtggaggc aaattggata ttcgtccgga tcgtacgata ttgttcggcg attggtgaag
    17581 atgggtttgt taacgtgatc aaactgactg catgagttgg tgttgctttt tgtttctgtg
    17641 ttcgtgccat ttttcttccc tcctaaactc ttgagcgact tctgcgtgat gaggctgttt
    17701 tatcgtttgt aacttttggt cgtgtaggag ccagtccttt tttacggata ccagctttca
    17761 attctttctc tgacatttct ggaactgttc ctaagattgg gaaccctaat gtatccgtca
    17821 catatttttc atctttcact gttcgatcga gtaattcaaa taagaatgcc agaactacac
    17881 ctaccatcat tcctaacatt aagccaatca ctagattcaa tttattattt ggcgaaatag
    17941 gtgtcgtatt ggcaactgca cctgaaacga tcgagatttt atcaacattc atcacgtctt
    18001 ttgcattctc ttggaaaact tgtgaagttg tgttagcgat ctgttgagca gtcattgcac
    18061 tcgtgcttat tgcttgaatc gagaacattt gtgaattttc tgattgattg attgagatgg
    18121 catccttgat ttgttcagga gtcattttca cgttgtcttc tgttttcaaa cgttcttgga
    18181 cttcatttag cactagatca ctgacgatca tatctttata cgtattgatc atttgcaagt
    18241 tcgtattgac atcattgaca tttgcagtat ctgattgcgg cagtgtcaca atcaactgtg
    18301 cttgcgaact gtattttggc gtcaaaatga aaaacgttac aattcctgag atagccaagc
    18361 cagcaaacat cgagatgatg attgttatca agtgtttgcg taatgtttca aaaatttctt
    18421 ccaagctgat tgtctcttcc attttttctc cactttccta tttattctct aaattcattt
    18481 gttcttttaa ttcttttttc acacgatcaa gttcattgtc attaactttt tgatatgaga
    18541 tgtcatcttg catgaagcct tctccttgca tctgatcttg cttgatcgta tcaaatgctt
    18601 cccgataatc taaagcaatc tttttcattt catcaaagct catgtctgtt ttcatattcg
    18661 actctagagc attcaaaatg gattgatagt tgctgacacc atttagactc aatacttttt
    18721 ttgctacgcc ttctacgatc tttctttggc gcccttgtct accgtaatca ccatttgggt
    18781 cttcataacg catacgagaa taagataatg cctgaacccc gttcaatgta attttaccga
    18841 ttggaaagtc atagccatct tgtgagaaag tgaggtcatt attgacttcg ataccaccaa
    18901 ctgcatcaac gagttccttt agccctttca tattgataga gacatagtga tcgattggga
    18961 tgtctacata tttttgtacg gtatccatcg ccatggcagc tccgccgaat gcgtaagcgt
    19021 ggttgatctt gtcttttgtg tcacgaccta cgatgtcgac atacgtatct cgaggaatgc
    19081 tgacgatcgt tgtctgtttg tcttcaggac tgactgtggc aaccatcatc gtatctgatc
    19141 ttccttgatc gacccgacct aaatctccag tatcaatccc catcaataga acagagaaag
    19201 attcttgttt gttcagatca actggtttcg ttcgttctcc ttgggttcgt tccactgact
    19261 cgtaagtttt ctcaatagaa tgtgagagat ccagatataa ttttgctcct actcctacaa
    19321 ttgctaatac taatacgata agaactgcta aaataatcag aaatattttt ttccctcttg
    19381 attttcttct tcgtcttgcc atagtttcct ccgtttgcta gctttgcttt aattgttact
    19441 aacttatatt gctatagccc atttgctgag caacagtttg tgcttttgtt gcgtatgctg
    19501 cgcgtatttt ttcattccgg atctgctcta tttgactgag caccgtcaaa tattgatcgt
    19561 aagtagcggt ggcagtcact tgaccatcct tcaacatcgt atcgaataac tgatctagtt
    19621 gcgtgacttg cgcgatctga gtatcagcga atcctagata ttgcataaca accgttttcc
    19681 aaggactatc tttaaaaaag ctcatatttt cacgtacacg agcgacatct gcacttgtca
    19741 ccttttcttt gatgacgaca tcgtctacag cttgctgcca gtttgataca tttttagtaa
    19801 ataaatcgtt gacagctgtc tggatcttca gttttgattc tgcatcctct aactgcgtta
    19861 agactgcttt cttttcttct tggatcgcag cagcttcttt aggtaattct gattccttga
    19921 tgtcataatc atctgccgaa agtttgatag aagatagttt atgtgacaaa tttgaaactg
    19981 tttcttctgt tatttcagga tttaggaaaa ttttttcttt tgtactgtac agcttatcta
    20041 cttcttttga taaagaggtc acggtgtctt tttgattggt gatggcagat tctgcgtaat
    20101 tgatccgttg atgatgttgc cgctgattat tgaaatggta tccaaacaag caaatcacaa
    20161 tagcgcctgt gcctaccgcc acagtagcca ataacttgac gaacggcttt tccatagatt
    20221 cactcctaaa tattgatgat agataaataa agatgtgatt cattcccatc agaatgagcg
    20281 ctttttattt taaaagcata attaaactaa tatattcata gaaatattta taaacaggtt
    20341 ttccctatat aatcatacca caaaaagttt tcttgactag ggaaattcct aatttaaaag
    20401 taaataaaac agtaacaaga tcatgattaa tcgttttcat ttttatttcc tctcttttca
    20461 tgagcatttt gaaaattcga acaaagaata aaataacaaa aattattaaa atagaattaa
    20521 taacagctat ttatatttat aacaaaaaaa cagagacaca gcacgtttcg tgcatgctct
    20581 ctgtttttca aacaaaagac tattttgtga tgatttgatc caagcttgct aatgacaaag
    20641 ccatggcagc tatttgacta agttgtgtta gtcggttctt acgtactgct ggttcatcag
    20701 ccatgaccat cgtttgatca aaataatttt cgatcagtgg acgaagagcg acaagctggt
    20761 cgtagttttc gtggatcgtt tggtcagcaa aacttgcttt cattgcttct actgctttgt
    20821 gtaattcttt ctctgcgtcg ttttcgaaca gctcaggatc tacttctgat tgtttttcaa
    20881 gctgcgcttt tttcgctaag ttcacgacac gtgtcaaagc ttccattgaa ggtttgaagt
    20941 cttcatctgc aagatgttgt ttgaacaatt gtgctgctgc aaatactttt gtcagatctt
    21001 tttgttccgc attcaaaaca gcatcgatga catcatgacg aatattcttc gttgtcaata
    21061 attggcgcag acggcctttg ataaagtcga tcacttgttg ttgcccttct gataaaccaa
    21121 tgccgaaacg atccgtatct ttactgataa catcgctaat cgtttcttgc agaacagaca
    21181 aaggaaaggc ccattttttc gattcgatga tccgaacgac accgtatgct tggcgacgta
    21241 aggcataagg atcgtttgaa ccgcttggga tcatcccaac agcaaagaaa gaaaagatgc
    21301 tatctaattt atctgcaatc gctaaaacag aacctactgt agactgaggt agctctcctt
    21361 cactggatat aggcatgtaa tgctcacgaa tcgctgtcgc tacagcaggt ttctcgcctt
    21421 tcagcagagc atatttttcg cccatgatcc cttgcagttc aggaaattcc cctaccatgt
    21481 tggttactag atcaaattta tagatttcag cagctcgttg cagatccatc aattcttcct
    21541 cagatagtcc tacttgttcg ccaatgatac gggcaatgac ttgtacccgt tgcattttct
    21601 catagatact accgattttt tcatggaaag taacagtttt tagtttttca acgtattggt
    21661 cgattgaagc tttcttgtct tcattataaa agaattccgc atcttctaaa cgagccgtca
    21721 atactttttg attgcctcga accacatttt ccaattttac ccgatcacca ttacgagcag
    21781 aaataaaatg aggaagcagc ataccttgat cattccgtac ctcgaaataa cgttgatgtt
    21841 ctttcataga agtgactagt acttcttcag gaacagaaag atatttttct tcgaagtcgc
    21901 cagaaaagac agttggatat tcgactaaat tgttgacttc ttctagtaaa tcttcgtcta
    21961 gatcaataac ccaatgattt ttttcggcta attcattggc ttgtgtaacg atcatttctt
    22021 gtcttttttg cggagacgca atgacgaatt gttcattcaa tttttcttca tattcttttg
    22081 catgcgcaaa tgtcacatct tcgcctaaga aacgatgacc tcgagaggct ctgcctgttt
    22141 tgacatccaa gatttcgaat gggattactt cgtcatctaa caatgccacg atccagtgaa
    22201 tagggcggat atattcaaaa tcgtattctg cccaatgcat cgttacaggg aaagtcaggc
    22261 ttttaatgac atctgctaaa cctgtcaata cttctttgga ttccttacca tgagtgtatt
    22321 tcgttacata gacatattcc acacctttta attctctaaa agtgatagcg tctgtcgtca
    22381 gaccttgtcc gcggacaaat ccttccgctg ctttcgtcca gtttccatct gcgtccaaag
    22441 caattttttt ggctggtcct ttgacttctt cttcactgtc cgcttgtcgt tctggaatgt
    22501 ttgttacttt gattgctaaa cggcgcggtg tggaaaatgt ttcgatcgta tcataagtca
    22561 attggttttc atctaaaaat tttgctgttt tttcttctaa ttgtttcatg cttggtgtga
    22621 caacatgagc aggcatttct tccagcccga tttcaagtaa taagtctttt gccatcttat
    22681 tcagcctcct tcacgttttc tggatttgct gtgtttttat tcaacaaagg gaatcctaat
    22741 ttttcgcgtt ctgccacaaa gattttggct acagcacgag ccatgttgcg gatgcgagaa
    22801 agataaccgg cacgctctgt tacggatact gcaccgcggg cgtctaataa gttgaatgta
    22861 tggctacatt tcaagatata atcatacgcc ggatgaacaa gattttcatc gatacagcgt
    22921 ttagcttctt tttcaaaacg atcaaagttg cttagtagca agtcttggtc gcttacttca
    22981 aaagaatatt tagaatgttc atattctggt tgtttgaaga tctcgccata tttcacgcca
    23041 tcagcccatt ctaaatcata gacactttca acttcttgga tataagaagc aagacgttct
    23101 aatccataag tgatctcaga agttactggt ttacaaggca gtccaccaac ttgttggaag
    23161 tacgtgaatt gtgtgatttc cattccgtca agccatactt cccaacccac accggcacag
    23221 cccatggatg ggttctccca gttgtcttca acaaaacgga tgtcgtgttc tagtggatcg
    23281 attcctaaaa ggcgcaagct ttctaaataa agctcttgga tattctcagg tgaaggtttc
    23341 atcacgactt ggaattgatg atgctgatac aaacggtttg ggttttcgcc ataacgtcca
    23401 tcagctggtc ggcgagatgg ctctacgtaa gcagcattcc atggttctgg tccgattgcc
    23461 cgtaaaaagg tatatgggct catcgtacct gctccttttt ctgtgtcata cgcttgcatc
    23521 agcatgcagc cgtttgatga ccaaaatttt tgtaatgtta aaatcatatc ttggacggtc
    23581 aattttttac tcatctgttt tgcccctttc aattttaaag cgttgctgtc aaataagaat
    23641 acaggaaaga aaacgacaaa aaatccctat gtctgattac agacataggg acgaataatt
    23701 cgcggttcca ccctacttcc gaataaagat tcggcagctt catttatcgt actcgcaagt
    23761 gcctcttcaa aaatcgtttg ggtccggctc ccactctccc gaactcgcta aaccacgtgt
    23821 tttttactga tcttggtcaa tgtacgtatt cattttgcag ttttcttgtt tctataatag
    23881 atcctctcag tgaacgatct atttgatcta cggttaataa tagacggaac tccctgtgtt
    23941 tgtcaaatgg ttttgatttt ttgttgtatg tttcatttac tattcttctt ttttaggtag
    24001 atctttttca gacatgtctt tctctgacgt ctttaatacg tgtgcccaag acttcatttg
    24061 atcaatgaac tttttgcttt tcaaatggat accgacatat tcatcataca gctggtcgat
    24121 gagttcacgg attgcttgtt tggtttcttc tttcagatgg attccactga ttttatcata
    24181 agaaatagct gaaaacatcc gaacgaaata aacagctcga ggatctgcat gataacggtg
    24241 atcatccatc gaccagtgtc tttcgcatat cacaccacca tatttggaag aatagtcaaa
    24301 ttttcctttt gtttccccac atacgacgca gtgtgtccag attggtgcaa ttccgaagcg
    24361 ttgcagtatt tggacttcaa aaatattcgt gatgatttct gcatcatctc cttggtccat
    24421 ccgttgcagt gcttgttgcg taaactggaa caaatgcggg tcgtactgat gatcttcgat
    24481 tgccgcatct actagattca ataaatatgt gccatagccg ctcaaaaaga tgtcttcttg
    24541 gatgtgtcga aacgcgtgga catctttgac actgcttaaa aatgacaaac cttcacttcg
    24601 aaaattcccg atataaactg cttcagtaaa agggagcaaa gccggagcta agggctgatt
    24661 ttgccgatgg atccctttga tataaaacat cattttgcca gaagattccg taaagatttt
    24721 gactaattta tctttttctt tgtaattacg gctagataaa atcaagcctt ttgattctgc
    24781 aagctggctc atattctccc tcctaaaaaa taaatctgga aaagcagatt ctgccgatcc
    24841 agatcattta tgttgcgatc ttccgcagct tttctcaaca cgcggatttt tatccagttt
    24901 atttctatac ctaacttaca agaagctcag aatatcaata ttcgtctttt cggtagccga
    24961 agtcttgcag atagactttt ttgtctcgcc agtctttttg aactttgacc caaagttcta
    25021 gaaagacttt gtctcctaaa agattttcga tatcttttct cgctttcgtt cctacttgct
    25081 tcagcatttt tccgcctttg ccgataatga tccctttttg gctatctctt tcgacaataa
    25141 tcgtagcctg gatatggatt ttatcattct cgtttcgctt catcgaatca acaacgactg
    25201 cgacagaatg aggcacttcg tctcgtgtta aaaacaagac tttctcacgg atcaattcag
    25261 aaacgatgaa gtattcagga tgatcagtca cttgatcatc tggaaaatat tgtgggccct
    25321 ctggcatttc actgactaat acatccatca aacgttcgac gttgtttcct tctgtagcag
    25381 aaattggaat cacttgtgca aacggcatct gcgttgaata atcttcgatg attcccaaca
    25441 actcgtctgg atggatttta tcgattttat tgataatcag ataaacagga gaatgcacgt
    25501 tttttagacg ttcaataata aaatcgtctc cccgaccgcg tttttgatca gcgctgatca
    25561 taaataagac cgcgtccact tctttcaacg cactgtaagc tgcttctacc ataaaatctc
    25621 ctaaacgatg ctttggttta tggattcctg gtgtgtcaat aaaaatcaac tgagcttctg
    25681 gtgtagtata tactccttgg attttatttc tagttgtctg cgccttatca ctcatgatgg
    25741 caattttttg acccacgatt cgattcaata atgtggattt tcctacattc gggcggccga
    25801 cgattgcgac aaaccctgat ttatgttctg gcatatacgt tctccttttt aattaaacaa
    25861 caaatgatat attttaggga caaataaaat caacccaacg atgacggaaa aacaagcggt
    25921 cactaaaact gctccagctg ccatatcttt gatttttttc ccaatcggat gaaaatgaaa
    25981 atccgtaaac atgtccacga cattttcaaa aacagtattg atgatctcta ctatccatac
    26041 gagaaaaaca gctaaaagca gccataacca ttctatccga tcaagctgga aaatcacgcc
    26101 cataaacaaa gcgaggattc cgaacgcaac atgtttcctc atgttgcgtt cttcctcaaa
    26161 aacggttttg actccttgga cggcaaattc cacggacatc aggaaatgtt tgtttttctc
    26221 tacgttttta tcttttaagt ccataggcat ctaagatctc tttctgtaaa ccaaacattt
    26281 ctttctcatc ctctggtgtc atatggtcat acccgttgat atgcaagaat ccatgaaccg
    26341 ctaaaaagcc aagttcccga tcatacgaat ggccgtaagc ttctgcttgc tctgcagcac
    26401 gttcagtaga gatcatgatg tctcccagta cacgaggcaa tggattctct ccatcttcaa
    26461 aaatcactgg gatttcgtct tcgccctctt cttccaaggc aaaactgatg acgtctgtcg
    26521 gtgcatcttt tccacggtaa tcacgattga ttacttggat cgctgcattg tccatgaaag
    26581 taacagacat ttctgtttct tctggcaact ctaaatatga tgctgcaaat tgcagcaagt
    26641 cgtcgatttc tttcattttc tcttctgaga cttggtttgt ttcatccatg aaagtaatat
    26701 ccattataca tcgcttcttt ctattcttct tgttcttctt ttatcttctc aacttccgat
    26761 ttcattttag gatatttgat ccgagaatgg aaggtactgc ttaaaccgct gatcaatgat
    26821 ttttctactt tacggatttc ttttaacgtc aatccactgt cgtccaattg tccatcggaa
    26881 atacgctctt caataagatt atggacaaaa ctttcgattt tttcgctcgt tggatggtcc
    26941 attgctcgta ctgccgcttc acaactgtca gctatattga cgattcctgc ttcacggctt
    27001 tgaggttttg gtccaggata acggaattgc tcttccgtga cttccgggtt gcgttccttt
    27061 gccttaacgt agaaataacg catcagcgtg gttccatgat gctgtctgca aatatcgatc
    27121 accatttgcg gcatattata atcttccaat attttggcac catctgtcac atgtccaaag
    27181 ataatatgtt tactgtcttc tggcaataag aaattgtgcg gattttccgc tcctgaaggc
    27241 aagttctcaa cgaaaaagct ggcgtgtttg atcttgccga tatcatgata atagcaagct
    27301 actcgagtta gtaaagaacg tccaccgatt tctgctacag cattagcact tagattggct
    27361 accatcatgc tatggtgata cgtgcctggt gcttcttcca gcaactgttt caataaagga
    27421 tgattaggat tgctgagttc atttaatacg atcacactat catcattgac catcaattca
    27481 atataggggt gcagacctat cgtcagcaag aatgagaaca gtgcacctgt gaatccgcat
    27541 actagcgtta accaagtcgt tgcatcccca aagctcattc cttggtagat aatcaaaatg
    27601 acatccatca tcacaggaaa aataatgacc cacatagcag cggataaccc ttgttctgag
    27661 atccgtttgc gtctgacgat cgttgccatg agaccagaaa atacatagga catcaaaata
    27721 actgtcagaa agttcgtgcc aatcgaatca taaaaaatga aaagtgcgga tactgcttga
    27781 aaaataccag ccatgatccc tgctcttcga ttcaagaaaa agcttaaaac aagtggagca
    27841 aaagccgcgg ggtaaaacag cggaatataa gcagcttgtt ctgtttggaa gagttggaaa
    27901 aatttcatta gtacgacgct tactgacatt gccgtcacgt agaaaagtac gtattttgtt
    27961 ctttctcctg cattttggaa ttgaagtgaa ttataaatca gtacaccgat ttgaagcaaa
    28021 acagctaaaa ccatggcaat gagtgggaaa atagaagtcg tttgattcgt caatcctagt
    28081 aattccaatt ttttcatcgc tgaagcatca atttgatttc cttcgcgaac aataatttct
    28141 ccttggaaga tcatcactgg ttgtacagct tctcgtgcag attgttttaa ttcttctgtc
    28201 tttttctcat tcaatacatc attaactaca atgccttgat ccactaagta gcgaatcatt
    28261 tgttgctgct ctgttgtgac attcaaatat tgaatctgat cttctgcttc ttgtttaaaa
    28321 gcttccaatt cgctttcacg aacttgttta ctcatctgtt cgtcaatgag cttcaaactt
    28381 tcatccctaa ccgtgtgaat ttccgtttca gtcatttcaa atatcgtcga ataaaaattg
    28441 ttcggcagtt tttggtaaaa cgcaacgttt tctgcattca cgttttcaaa atttttcttc
    28501 agtgtagcaa tccgctcttc tgtagtaggt ttcgggatat tttcatcttc cttcgcctta
    28561 tctaccttgt cattataaga tttgttgatg gtatcattcg tcttatcgat caattcgaat
    28621 aattgcttga tccgattgtt ctggtcatct gccagatctt tttgataagt atattctgga
    28681 gtcactgctt ctgctgccag ttttcttctt tgttcggttt cttccgtgtt ctcaatcgtt
    28741 ttattcgcac ggatactctc ttctgctact tggccttctc tgaaatcatt ggccttttgt
    28801 ttgacactac taaatgtaac gccgcagaca atgataaaaa acaagaacag aaggaaaggc
    28861 aatgctgcct ttccgagttt ttcttgtagt ttctgcagtg ttttattcaa catgtgctta
    28921 tcctcctaag caaagcttat tcttgatgaa gatccgcctt ttcataagct ttgatgattt
    28981 cggcaactac agggtgccga acaacgtcac ttgcttcaaa attaacaaaa tcgatttttt
    29041 tgatttgctt taatgttcgt tctgcatgaa caagaccact tgtcgtccca cgaggcaagt
    29101 ctatctgact tgtatcccca ttgacaatca tttttgattg ataaccgaga cgggtcaaga
    29161 acattttcat ctgagcgact gtcgtgtttt gtgcttcgtc caagataacg aatgcatcat
    29221 ccaatgtccg cccccgcatg taagctaaag gtgcgatttc gatcacgcct cgttccatca
    29281 atcggttcgt atgatccaat ccaaaaattt ggtataaagc atcataaaca ggccgcagat
    29341 aaggatccac tttttctttc agatccccgg gtagaaagcc taggttttcc cctgcctcca
    29401 cagcgggccg cgtcaaaatg attttttgca cttcgccttt ttttagggca gcaattgcta
    29461 atactacggc aagaaacgtt ttccctgttc cggctggccc tacaccaaat acgatgtcat
    29521 gtttggctac cgattcaacg tatttctttt gaccgctgtt ttttacccgt ataggttttc
    29581 cattacggtc tttgacgatc tcttcctcat acatctcaac aaaataatct aatgtacctt
    29641 tttgccccat cttcaatgcc gtcacaacat ctggcgtact tacgtggatt cctcgtttga
    29701 tcaattcctg taatgtccga atgactgagg cagccaagga aatctgggat tgctcaccaa
    29761 tgatctgaat gatttctcca cgtgtatgga tggttgtttc cgttgtttcc tcgatcagtt
    29821 ttatatgctt gtcgtgtgca cctaaaagca tgctgacatc atcagcagct gtcaatctaa
    29881 tctctaaaga actagactct tccgtcaaaa atagacatcc cctttttttc gattcattct
    29941 ttcctatttt accatactca gaagaaacta tatagcaaat aagaaaaggt tgtaaaagag
    30001 tcgtttaacc atacgtacca agaaacgtta aaaaatagcc gtttccattc gctaaaggtc
    30061 tcgttttgat aaaaagaagc tgagaatgta agttatatga aagtggagaa caaaatattc
    30121 cgtttcattc agcaggtatt ctctaggtat ttttcttgtt tcaaaaaaag aaaacaaaat
    30181 agttaaaata ttcttgcatt tcaaaaaaaa caggtgtatt attacgtcaa caaataaaca
    30241 tacagcaaag cgtcgaggaa aacagtaggc tattcaacga tttattccca gtgagtcatg
    30301 taagtgagaa atgacaataa atcgaataga cgaacatcat ttccgagtca atgtcgaaaa
    30361 cgtagatcat tgtggctgcc tccattatca ggctagcgga taactttatc aaaaagcgtc
    30421 cgtgaatgaa gaagcttttt taagcgaaaa aaggtggtac cgttctagaa tctagagccc
    30481 ttttcccaag tggaaaaggg ctttttttat attttaaggt ggtggttttc atggaatctg
    30541 atattagtgg cattactaat tgctgcaacg tttatatcgt caatcaaaat gataattatt
    30601 ggaggaaaaa tttatggaag aaacaaaaac ttattcatgg aaacaactat tgatggtcag
    30661 ttcacttatc ttcgggatgt tcttcgggtc aggtaatcta atctttcctg tccacttagg
    30721 tcaaatggct ggcgcaaact gggtcagtgc tggcgtagga tttgccatct cgggcgctct
    30781 tttcccatta ctagctatct tagctgtagt agtgacaaaa agtgatggtc tgtatgactt
    30841 agctaaacct gtcggaaaat ggtatgctgc cttgttctta atccttgttc atttgacgat
    30901 cggaccattt ttcggtacac cacggacagc tgctactgct tttgaaatgg ctgctaaacc
    30961 atttttgcct gaaaaatata attcattagg tatgttttta ttctctgctc ttttcttttt
    31021 acttgcttat ttccttactg tccatcccac acggttggtc aaatacgtcg gaaagtatct
    31081 aaactccttg tttcttgcat tgttagcaat catttttgtc gtttctttat tccacccaat
    31141 gggaaatcta aatcaatctg ctgcagatac ttaccaaaca aacgctttaa caaatggtgt
    31201 cctagaaggt tataacacgg ttgatgcagt agccttgctt gccttaagtg tcacttttgt
    31261 ccatgcagtc cgtgaccttg gtttcaaaga taaaaaagtc acagaattaa cagcaaaagc
    31321 tggtagcctg agcgttgcgc tagaagtcat gatctatttt ggtcttgttc ttctcggtgc
    31381 gatgagtttg aataagatgt ctttatcaga aaatggcgga actgcacttt ctcagatcac
    31441 taatttttat ttaggtaact tcggcgctag cttcttagga gtgatggtca cattaggtgt
    31501 cttcactacc gctatgggac tcgttgtttc ttttgcgcaa gatttccata aactgttccc
    31561 taaagtcagt tatatgacat ggctgcggtt aacgactttc gtctcttttg tcgttgcaaa
    31621 tgctggttta gacaatatca tccaatggtc tttaccagta ttgatgcttt tgtatccatt
    31681 gtcgcttgcg ttgatcttgc tttccttaac agcaaaattt ttccaaaaga caccatttgt
    31741 ctatcaagta acgatgttgt ttgctgctgt tcctgccgta ttggatatgc tggcaaattc
    31801 gcctgcttta gtgagtcaac aaagagttgt agcaagcatg ctcgaatttt atcatcatca
    31861 cgttcctttt gctgcattag gacttggctg gatggtccca acgttacttg gttacgctgg
    31921 cagcctactg ttttattacg cctatcgcct atcagggtat aaacaagaag caaatgaact
    31981 accagaagaa taaccaaatc aaacacaatt taacataaga aatattaaac aggaaaaaac
    32041 cagctagatg aaagaatcct attctttcgt ctagctattt ttttgttctc ttttttacgc
    32101 gcacaaaaaa actgcggaca atgattgtcc gcagtttaaa tgataaaatt aagattgtaa
    32161 tagttctttc acaatggcat ttacttggtt tccatctgct tttcctttga ctttaggcat
    32221 gatcgcaccc atgactttgc caaattcttt cattgatgaa gcaccagttt gtgtgattgc
    32281 ttcttgaaca agttgtcgaa tttcttcgtc ggaaagttgt tccggcatgt atttttcgac
    32341 tatcacaatt tcacttttta ctttttcagc taaatcgtca cgtcctgctt cttcaaactc
    32401 atgcaaagaa tcacgtcgct gtttcatttc gcgagacaac accgttaatt cttcttcttc
    32461 tgtcaagtcg tgaccttctt taatctgctc gttttgtata gatgacttga tcattcggat
    32521 gacttgtaaa gattccttat ctttcgcttt catcgctgtt ttcatgtcat cgtttaatct
    32581 acttagtagt gacacactac caactccaat tcatcacaga actagaattt tttgcgtttt
    32641 ctagctgctt cagatttttt cttgcgtctt acacttggtt tttcgtagaa ttcacgttta
    32701 cgagattctt gtaaagtacc cgcttttgac acggaacgtt tgaagcgacg aagagcatcg
    32761 tcaagtgatt cgtttttgcg aacgactgtt tttgacatgt taattccctc cctccgagct
    32821 taaaaagtaa ccgtaattgt tattgaaata tatctcaaaa aacaagactg tcctgtaaat
    32881 attatatcta atgctgtttt gaccgtcaag gaaatcttgc ttttttttaa aattatcaaa
    32941 tgttatttta tttaaatcct tattgacaat tttcacatct tccgaaaatc tcgaatctat
    33001 gcccttcgat cgtacatcca ccgagctgtt cttcgaaata attcattgga cacatatgga
    33061 tttctttcgt tgttccgcac accgtacaga taaagtgatg gtgatggccg atttcccctt
    33121 gacagcaatg aaaacgaaac ttcatctctc catttaaatc ggtttcttcc agtaaatcga
    33181 tttctgcaaa atcatggaga tttcgataaa tcgtatcgta acttactcct ttgaattcct
    33241 gattcatata gtcaaaaact tctttagcgg atacgtagcg attgcgcttc actaaataag
    33301 ttaacaatgc ttctcttttt ttagtatatt taaaaccgtt atttttcaat gtttctagtg
    33361 attgttcaat caatgtctgt tttttcatga cttattcctc caaatcaaaa tgattacgaa
    33421 gtacacattc tagagtatgg tataataaac ataaaaaaaa tgcaagtgag gttttatcca
    33481 tgtcttccga ttctacagaa atcgttactt tttttgtcat ctctgactct gctggagaaa
    33541 ctgcgacaaa attagcgcaa gccactatgg cccaatatcc taccgttgag ttcaatttat
    33601 tccgcagaac atttgtgaca gatgagaaaa cattgatgca ggcactgcaa gatgcactaa
    33661 aagaaaaagc ccttgtcctg cacacattga tcaatcaaga attgatcgag atgacgcgtt
    33721 ctttttgtga agaacatcaa ttatttagtt ttgatgtgat gactccgccg atatcagaaa
    33781 tcgagcgctt aactggtatc aagcccattc ggcaacctgg cgcccttcat ttattgaatg
    33841 agaactattt caaacggatc aaagcaatgg aatttgctgt aaaatacgat gacgggaaag
    33901 atcctcgtgg gtttctagaa gcagatgtcg ttttgctagg cgtatccaga acttccaaaa
    33961 cgcctttgag cttgttttta gctaacaaaa atttaaaggt tgccaatcta cctttgatcc
    34021 cacaagcaca tattcccaaa cagctttggg agatcgatcc taaaaaaatc gtgggactga
    34081 cgaataaccc agatatttta aacaatatcc gtaaagaacg gatgcgctct tacggattaa
    34141 atcctgatac tgcttattcc gatatcgaaa aaatacgagc tgaactcgat tttgcgaatg
    34201 atctttatga aaaattgggc tgcgtagtaa tcaatgtcgc ttctttatct atcgaagaaa
    34261 cagcttcact tattttgaat gctttagacc tagaagatca tagttattat ggaactgaaa
    34321 ccaccgaaga aacagactaa cagtttttct tgtctttttc ttaaaaaaac tggactgtgt
    34381 cagcgaagaa gattcgttga tacagtccag tttgtctcta tttgcaccta tcgttattga
    34441 tgttccacat gtttgagcgt ctggttcaaa atatccagta cgtgagaatc atcaagacta
    34501 tacaaaatcg cttttccctc acgatgggac ttgacgacat ggttttctct taataaacgc
    34561 agttgatgcg atacagcaga ttgttccatt tctactgctt gggtgattgc tgtcacattt
    34621 tgttccccgt ctttcagata cagcagaatt ttgagacgag tggggtcact caacattttg
    34681 aatagttggc tgactttctc tacttttgtt ttttgcgtgt ctggcaatcc attcacctcc
    34741 aacttgaaaa aagactgact tctaaagttt accacttttt ccatcagtct caagtttttt
    34801 tattcttctg tcattttttt gataatcgct tcataagcgg ctactttttc agctgcgtct
    34861 tctgaagagt ttccttttac accgatataa aatttgattt tcggctcagt tcctgaagga
    34921 cggatagcga tccagccatt ttcttccagc gtatacttca atacgtcaga tggcggtgtc
    34981 gttagttttt ctacgtttcc ttcacggtct gttctcgtca actctttgaa gtcttctgtt
    35041 tggatgactt ttgctccggc aaattctgtc ggtgcttctt cacggaattt ttccatcaaa
    35101 gcagagattt ttgcagaacc ttcttgtccg ctcattgtca cagaaatcgt tttttctgcg
    35161 tagtagccat atgtttcaaa aatcgtttgc aagccgtcat acaacgtttt gccttgtttt
    35221 ttatagtaag ctgctacttc tgctaataag agcaatgctt gaatcgcgtc tttgtcgcga
    35281 acgaaaggtt taactaaata accgtaactt tcttcgaatc cgaacataaa agtatgggaa
    35341 tgatcttctt caaattgttg aattttttca gcgatgaatt tgaatcctgt caatacattg
    35401 aacatggtag ccccatagtg ttccgcaatt gctgtaggca attcgctaga aacgattgat
    35461 ttcaataccg ctgcattttc aggtaaagtg cctcgcgatt ggtgtgcttc caaaatatat
    35521 tgagcaaaca gggctccgat ttggttccct gtcaatactt cataggagcc atttggcaaa
    35581 cgaacggctg cgcctaaacg gtctgcatca ggatctgttg caatcagtaa gtcagcgcct
    35641 tctttctcgc caagtcgcat cgcatactcg aaagcagagt gttcttctgg attcggtgat
    35701 ttgactgtag tgaaatccgg gtctgcgaca gcttgttctg gaactagtac gaattgttcg
    35761 aatccagctt gtttcaacgc acgttcgccc aacatttttc ctgttccgtg aagtggtgtg
    35821 tacacaagtt tcaaatcttt acccattgtt tccaccaatt catgatcaat cgttactgct
    35881 ttgatttctt ctagataagc ggcatccact tcttctccga tgatcgtgat caatccgcta
    35941 tgttcagctt cgtcgtcaga taatacttca acttttaacg gattgctgac ttcacggaca
    36001 tatttcgtca atgcatctgc gtctgcagga ggcatttgtc ccccatcttc tccgtagact
    36061 ttatatccgt tgtaagctgc tggattgtgg gatgcagtta ccatgattcc cgcaaacgtc
    36121 ttcaaatgac ggactgcaaa agaaagctct ggtgttggac gtaaactttc gaatacataa
    36181 gaagggatat tgtgatgtgc taatgttttg gctgcttcca tggcaaattc tggtgattga
    36241 tggcgtgagt cataagcgat agcgacacct cggcgttttg tttcttcacc ttgtgtatcc
    36301 atgaaacgtg caagtccttc tgttgcttgt cttaccgtat agatgttcat tcgattgatc
    36361 ccaggtccta agattccccg catgcctgca gtaccgaatt ccaacggtgc ataaaaagca
    36421 tcttcaagtt tttcaggatc ttcacccaga tcaattaatt gtttttttaa gttttcttct
    36481 aaattttctt catgtaccca ttgttcatac acttgttccc aagacatgaa aataacacct
    36541 ctttctgaaa tatggttctt aataagtata gcattcactt attagatatg aaagtacgag
    36601 gtctaaaaaa cgcttaaatc aagaaaggat tcttttatca agcacggttg caagtattcg
    36661 cataaatcgg attcagtaga tttcacgcga aaaaaaagag taaaagaaca attgaaaccg
    36721 ttcttccact ctttttaaac ttatgcagtt gtttcttcta aagattccaa gtatttatac
    36781 acttgttgtc cagcgatccc accatcacca acagcagtag tgatttgtcg caaatctttt
    36841 tcacgaacat ctccgatggc aaaaacgcct ggtatattcg tcttcatttc gttgtctgtt
    36901 ggaatccagc cagcttcgtt cgtcaaccct gcttctctaa atggtgcagt taatggatcc
    36961 agtccaacat agatgaatac tccgtctgct gccaaatcaa actcattgcc ggttttgaca
    37021 ttacgtgctt tcacacctgt cactaccatt tcattcccaa cgatttcgtc aacgactgta
    37081 tcccacataa aggaaatttt ttcattcgca aatgcacggt cttggatgat cttttgtgca
    37141 cgtaattcat ctctacggtg gacgatgact acttcagaag caaattgtgt caaatagatg
    37201 gcttcttcta ctgctgagtc tcctcctccg atcactacta gacgtttgtt acggaaaaac
    37261 gcaccatcac aaactgcaca gtaagaaacg ccacgtccag caaattcttc ctcgccaggt
    37321 acgcctaatt tacggtggat acagcctgtt gcgataatga ctgtttttcc ttcgtaagtt
    37381 ttatcttcac aaataacttc tttgtggctg ccgtgatcct tgatatcttg cacgattcca
    37441 taagcatttt ctgtcccaaa tcttgaaaca ccttcataca tcttataagc tagatcagga
    37501 cccatgattg aatcgaaacc aggatagttt tcgatttctg ccgtattgtt catttggccg
    37561 ccaggggcgc cttgttcgat catcaatacg gataagtttg aacgtgaagc atataaagca
    37621 gcagtcatcc cagcaggacc tgcgccaata acgattacat catacatatg tagattctcc
    37681 tttacttaat caagtaagca tactttacag ccaatgcgaa aaaaagtcta ttgttctgct
    37741 tgcgtttctc gaatagcttt attatactcg aaaaatccgc tgaaaaacaa tagactttta
    37801 caaatcattg atcaatcatt cgaaagattt tctccatttg aatcaattac ttttttatac
    37861 cagttgaatg atttcttctt cgaacgggct aatgtgccat ttccttcgtt gtcacgatcg
    37921 acataaatga atccgtacct tttcttcatc tcacctgtac cagctgatac taaatcaata
    37981 catccccaag tcgtatagcc taatagatcg actccatcta attctactgt atctttcatt
    38041 gcctggatat gtgctgccag atagtcgatt cgatagtcat cttccacata accattctca
    38101 tcgggcgtat cgactgcacc taagccgttt tctacaataa atagtggttt ttgataacga
    38161 tcataaatat cattcatcgt tattctcaag cctaatggat caatttgcca accccattca
    38221 cttgcttcca gatatggatt tttgacagaa gcaaagatat ttcctgcagt ctgttccaag
    38281 agttcgttgt cagtagtcga aactcgagaa gaataataag aaaaggagat aaaatcaaca
    38341 gtatgttctt tcagcaatgc ggcatcccca ggttccattt tgatctgaat gccatttcgt
    38401 tccatttctt tcaatgcata agcgggatat tctcctcgtg actggacatc aatgaagaaa
    38461 taattttctc gatctgattt tctagaagcc caaacatctt caggattgca agtgtatgga
    38521 taatatgctc ctgctgccag catacagcct actttgttct ccggatctac ttcatgagca
    38581 atcttcgttg cgatggcact tgcaaccaac tcatgatgtg ccgcttgata tttgatttgt
    38641 tcttcatttt ctccttcttc aaaatacagc cctgcgccca tgaatggtgc atgaaggatc
    38701 atattgatct cattgaatgt caaccaatat ttgacaagtc ctttatagcg attgaagatg
    38761 actcggcaca gattttcata aaaaccaacg agttctctag aacgccacgc accatattct
    38821 ttgatcaaat gcatcggaca atcaaaatgt gtaatcgtca caagcggctc gatcccgtac
    38881 ttttgacatt ctttaaagac atcctcataa aatttcaaac cagattcatt tggctcattt
    38941 tcatcgccca ttggaaaaat acgactccaa gcaatggaca tccgataagt cttgaacccc
    39001 atttctgcaa acaaagcaat atcttcctta taatgatgat acatatcgat cgcaattttt
    39061 gctggataaa aatgatcttt atcaaattca aacattttct tttttccagt aatgacagga
    39121 aaacggtctt ctccgattgg cacaacatct acgttcgcta acccacgtcc gccttcatca
    39181 taaccaccct cgcattgatt ggctgctgta gcaccgcccc ataaaaaatc ttttctgaat
    39241 cccatcatac ttcctccatt acatgtgtat tgcttgacaa ttctcttgcc agttcatctt
    39301 ggacttcgat tccttctgct tttaaccggc tgattgtttc cttgaattgc ggtaaatact
    39361 gctgatgtgc aataaacaac tcatccatga tccgttttgc tgtctttcct gatcgtataa
    39421 gcggattgat cgtaaacgct tgtaaagctg ttccataatc accagtcacg gctgcttcga
    39481 tcgtcagcaa ttccatattc ttcattactt gcaaccagcc tctttcagca gcaggaaggg
    39541 aaccaaacgc tacatttcgt gcgccttgtg cgccaacata ggcagtgact tctactacac
    39601 aatctgccgg cagatcagga acagctccat cattctttgt agacaccacg atctgtgttt
    39661 ctttatttcc atagatcgaa gcaatcgttt cacaggcagc atctgaataa taagcaccac
    39721 ctcgtttttg caattgttca ggtttatgat ccaattctgg atctttgtat aattcaaaca
    39781 gctctgcttc tgtttctttc acttgttgcg ctcttgtacc aatcgtttga tattcttcta
    39841 aagcatgttc caacatttct tcttcacggt agtaatagcg gtggtagcca caagggatca
    39901 tgttcatttg ttttaattgt tctttgaaaa acgggatgtc aaagatattt ttcggcaatc
    39961 cattgtcttc atcgtataaa cgatcaatca aatctgctgt gcggtcattt cctttattat
    40021 ctgctacttt gtgccaatgg aagtgattta gaccggcaaa cttgtagatc agctcttctt
    40081 ttttcttgcc aagcattgct ggttctgtca tcgtcgccat tactggcaca ttgcataatc
    40141 cgatcacttt atcccatttg ccatatctga taactgcttc tgtcaccatc ccgcttgggt
    40201 tcgcgaaatt gatcagccaa gcatttggac ataaacgctt catgtcttca acgattgcca
    40261 aaaccactgg aacggtacga aaagctttga atatcccgcc agcaccattt gtttcttgcc
    40321 caatcatccc ataataacta gggatccgct cgtctttgat tcgtgcatct aattgaccga
    40381 cacgaaactg agtcgtaaca aaatccgcat ctttcaatgc ttcttcccga tccaaagttg
    40441 catagatctt gacttcatac ggagaagcat cccacatacg ctgagacatc tgactgacga
    40501 tctcaagctt ttcttttcct tcttctacat ctacgagcca gatttctcgt atcggtaatt
    40561 cctcatatct tttgataaat ccttccatca actcgggggt gtaactgctg cctccaccaa
    40621 tcgtagcgat tttgattcct tttgccatgt tctcactcct ttgcttttta cacttttatt
    40681 atcttttttg taaacaaaac aaacaataga aattcgtttc tttccagtaa catttacaaa
    40741 agttagtgtt ttctactgga tttttgtaaa tatc
//
LOCUS       DAIGQM010000019        39448 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.019, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000019 DAIGQM010000000
VERSION     DAIGQM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.019"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(207..401)
                     /locus_tag="NOA48_000995"
     CDS             complement(207..401)
                     /locus_tag="NOA48_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789276.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(501..587)
                     /locus_tag="NOA48_000996"
                     /pseudo
     CDS             complement(501..587)
                     /locus_tag="NOA48_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1753..2793
                     /locus_tag="NOA48_000997"
     CDS             1753..2793
                     /locus_tag="NOA48_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0789277.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3617..3949
                     /locus_tag="NOA48_000998"
     CDS             3617..3949
                     /locus_tag="NOA48_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCI0789278.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4540..4869
                     /locus_tag="NOA48_000999"
     CDS             4540..4869
                     /locus_tag="NOA48_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789279.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            4856..5197
                     /locus_tag="NOA48_001000"
     CDS             4856..5197
                     /locus_tag="NOA48_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCI0789280.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5311..5550
                     /locus_tag="NOA48_001001"
     CDS             5311..5550
                     /locus_tag="NOA48_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789281.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            5617..5856
                     /locus_tag="NOA48_001002"
     CDS             5617..5856
                     /locus_tag="NOA48_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789282.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            5942..6613
                     /locus_tag="NOA48_001003"
     CDS             5942..6613
                     /locus_tag="NOA48_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0789283.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            6666..8642
                     /locus_tag="NOA48_001004"
     CDS             6666..8642
                     /locus_tag="NOA48_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0789284.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAVKNAEGKYYGGLVDTDKDGVKEAVWVDNVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGGLSAVVYFKKKA"
     gene            8655..9410
                     /locus_tag="NOA48_001005"
     CDS             8655..9410
                     /locus_tag="NOA48_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0789285.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            9407..10231
                     /locus_tag="NOA48_001006"
     CDS             9407..10231
                     /locus_tag="NOA48_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789286.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQPVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            10533..12632
                     /locus_tag="NOA48_001007"
     CDS             10533..12632
                     /locus_tag="NOA48_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0789287.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVLDGKNYDGALWYVEANGTWKKADTGGKLTVSSNTVTYTASDSFLANA
                     ANYGRDYILQLHMKAKNDAKGIAPNVATVTFNNDPNKGTQRTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(12670..14727)
                     /locus_tag="NOA48_001008"
     CDS             complement(12670..14727)
                     /locus_tag="NOA48_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HCI0789288.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNHEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKASQAQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(14841..15053)
                     /locus_tag="NOA48_001009"
     CDS             complement(14841..15053)
                     /locus_tag="NOA48_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789289.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            15240..15707
                     /locus_tag="NOA48_001010"
     CDS             15240..15707
                     /locus_tag="NOA48_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789290.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            15704..15946
                     /locus_tag="NOA48_001011"
     CDS             15704..15946
                     /locus_tag="NOA48_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HCI0789291.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            15964..16266
                     /locus_tag="NOA48_001012"
     CDS             15964..16266
                     /locus_tag="NOA48_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789292.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            16337..18391
                     /locus_tag="NOA48_001013"
     CDS             16337..18391
                     /locus_tag="NOA48_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789293.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            18391..20223
                     /locus_tag="NOA48_001014"
     CDS             18391..20223
                     /locus_tag="NOA48_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI0789294.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNSVTCLA"
     gene            20936..22834
                     /gene="ltrA"
                     /locus_tag="NOA48_001015"
     CDS             20936..22834
                     /gene="ltrA"
                     /locus_tag="NOA48_001015"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0789295.1"
                     /translation="MTNTKGISLKNKQLRHAEYYDMTETFDELHAMSVAKSNFKNLMK
                     FIIDDNNIFLAYRNIKKNKGSATAGYDGVTIKDIEKLACGDFLTIIKRRFKDYRPRKV
                     KRVEIPKPNGKLRPLGIPSIWDRIVQQCILQILEPICEAKFNKHSYGFRPNCSTENAI
                     ADCLARINQSKMNYVVDIDIKGFFDEVNHTKLMRQIWTMGIRDKQLLVIIRKMLKAPI
                     VMRNGNVVFPTKGTPQGGILSTLLANICLNEFDWWIANQWEERTVKELKHHYRKNGAW
                     DKGNIYSKLRSHTSLKEMYLVRYADDFKIFCRTGEEAQRAFYATQKWLRERLKLPISM
                     EKSKVTNLNKAESEFLGFSIRLHKKGKKKVAFTYVCRKAEENIKNKLKQQIKKIQYAG
                     AKKNRHRAIGDYNMMVIGIHNYYRIASHCSVNFTEIYRSVRTVIEARLKARGMTKNGI
                     YGQDHEGYRPYLKSKQMRYIEGFPILPIGYIKKRTPLNKRRNLNKYTKEGRKLIHQEQ
                     QAIESWKIKYLVKGFSNNKKYTVEFSDNKISKFISQKGKCAITGNELLMEEIECHHIN
                     PYHLSKDDSYKNLVIISREIHRLIHATSEETILKLLRLLKLNHYQIRKLNTYRKKAAN
                     FPISIKMN"
     gene            22951..23751
                     /locus_tag="NOA48_001016"
                     /pseudo
     CDS             22951..23751
                     /locus_tag="NOA48_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            23748..26279
                     /locus_tag="NOA48_001017"
     CDS             23748..26279
                     /locus_tag="NOA48_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789296.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            26331..26663
                     /locus_tag="NOA48_001018"
     CDS             26331..26663
                     /locus_tag="NOA48_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789297.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            26664..27257
                     /locus_tag="NOA48_001019"
     CDS             26664..27257
                     /locus_tag="NOA48_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789298.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            27420..29114
                     /locus_tag="NOA48_001020"
     CDS             27420..29114
                     /locus_tag="NOA48_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCI0789299.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            29802..31679
                     /gene="ltrA"
                     /locus_tag="NOA48_001021"
     CDS             29802..31679
                     /gene="ltrA"
                     /locus_tag="NOA48_001021"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0789300.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            31810..32187
                     /locus_tag="NOA48_001022"
                     /pseudo
     CDS             31810..32187
                     /locus_tag="NOA48_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            32246..32509
                     /locus_tag="NOA48_001023"
     CDS             32246..32509
                     /locus_tag="NOA48_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HCI0789301.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            32509..32844
                     /locus_tag="NOA48_001024"
     CDS             32509..32844
                     /locus_tag="NOA48_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0789302.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            32918..34120
                     /locus_tag="NOA48_001025"
     CDS             32918..34120
                     /locus_tag="NOA48_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0789303.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPL
                     PFLNSSKK"
     gene            34136..34780
                     /locus_tag="NOA48_001026"
     CDS             34136..34780
                     /locus_tag="NOA48_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789304.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            34791..35597
                     /locus_tag="NOA48_001027"
     CDS             34791..35597
                     /locus_tag="NOA48_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789305.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            35619..35849
                     /locus_tag="NOA48_001028"
     CDS             35619..35849
                     /locus_tag="NOA48_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789306.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYLAAKKYFTADNK"
     gene            36407..36685
                     /locus_tag="NOA48_001029"
     CDS             36407..36685
                     /locus_tag="NOA48_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789307.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHALLDYKKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIEQ"
     gene            36724..37146
                     /locus_tag="NOA48_001030"
     CDS             36724..37146
                     /locus_tag="NOA48_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789308.1"
                     /translation="MAKATRKHIYLYDMHIEVLDEIISTHDDISNYSEAVRHLCMMYD
                     PKTEEKISPSQIKLNAIGKEVSILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            37166..38758
                     /locus_tag="NOA48_001031"
     CDS             37166..38758
                     /locus_tag="NOA48_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789309.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTLEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEYGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTEREKIEYQRLNQAMEKYQAEPHKKTSGTLPGVFSISSDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEVGLKAAGRK
                     MMETLFEKEKLNDTGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QTQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            38788..39123
                     /locus_tag="NOA48_001032"
     CDS             38788..39123
                     /locus_tag="NOA48_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789310.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            39264..>39448
                     /locus_tag="NOA48_001033"
     CDS             39264..>39448
                     /locus_tag="NOA48_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789311.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        14508 a         5978 c         7876 g        11086 t
ORIGIN      
        1 tattgaaagt aactctatgt agcaaaaaat atctagaatt tcatttcctc aaaactgatc
       61 gatattgtat ctaaaaatat atactaccta aaataggtag tatatattaa aatatgtgct
      121 tttgttagaa aaatcaatac ataaattatc atatctgtat atgtcattta ggtatttcag
      181 ttatgttata atagttttgc tgtctgctac cccggcctaa tctggcaagg ggaggaggag
      241 atataatgaa ataccttttt gattttgttt ttgcaatcaa gccacttgca gatgtagtgt
      301 gcagttacct ctgcaaatgg cttgattgca aaattgccaa aaaagacagt aagcctaccc
      361 gttaattcta taatatagaa acgtaaaaaa aaccccatca gcctgcacgc tgatggggtt
      421 tggtgatata atgaaatacc tctttgttac tcataattat accataatta gtcacgaatg
      481 caaccaatag aaaaaactac ttagaacggt agatcatcgc taataacaat gcattgtcca
      541 ccaaatggat tttgtgaagc attaaataca ttgttattaa ttgtcgctgc ttttaactag
      601 gcctctcccc ttctattata aaagaagata tatatcattt cttaattacc tactacctta
      661 aaccaaaatt taagtactac ctaatttaag tagtacttaa acaatctaaa aaatagttat
      721 cccaattgtt atgcttttat aatacgatta tttgtaacaa aatgaatatt atataattaa
      781 acactaccat atttaggtag tgtttaatta ttagcaaaac aaaaaatatt tattctattc
      841 tcttaacttc aactaagtta tgctgcacac ctttatataa atcatatgca actcattagc
      901 tagacaaact acaagcatgt agttttatct gttaattatg tactacctaa ataaagtagt
      961 ttataattag caagtatata tatttaaaaa tttaagatta atttttttat gacttgtaca
     1021 aatttatctg atattctctt attaagaact acctaatttg ggtagttctt attttttaca
     1081 ttttaagtag tatttaattg caatttggta gtattttttt attatcttat tcttagaacg
     1141 gtagtactta atataaatat aggtagtatc taatttaagt attaatggta gtatctaaat
     1201 taacaggtag tatgtaacta ctttaaagta atttttttca gattaacaca gtagtatctt
     1261 attaaataag ttaattttaa tggtagtaca taattattat atatatctga cattggtagt
     1321 acttattgta ttttttagta gtatataatc tattgttttc tagcctaaag ccttgtctta
     1381 taagaataat ataatatata ctactgaaat aaggtagtat atattactag taatggtagt
     1441 atgttttata tgcataaggt agttcttaat ttattttttg ttttgacact ggtagtactt
     1501 aattatcttt aattttaaaa ctaaatttta ttcatacgtt tttctggtag tatttaatta
     1561 taaataatat ttatttaaag tagttcttaa tgactttaaa ggtagtacat aattcatttt
     1621 atttctgatt ttaggtagta tttaattaaa aaacagtttt aatgcgtttg cattttttat
     1681 ttatctttgc tattttcgaa aagagtaggt aattttacat aaataaaaca acgtgaaagt
     1741 agaggatcta caatgactga ttttaaattt tttaaggcgg atagagttta caacgaatta
     1801 ttttatcaat ttccaaaagt ctttattgtt tctgacgaat acaaaaaaat gaaagattca
     1861 actaagattg cctatatgct tttaaaagca agattagaga tcgcaatcag caaacggcaa
     1921 atcgatgaag aaggtaatgt ttattttact tatacgacaa atgaactatg tagagtatta
     1981 aactgccaaa aacaaaaagc gatagcaatc aaaaaagagt tggaatcctt tggtttatta
     2041 ttacaaaagc agatgggatt taacaaacag ttagggaaaa ataatcctaa tagactatat
     2101 ctagcagaat taaaagtctc agaaaatgat atctacttac tcgaaaaatt tgatagagag
     2161 aatagggaaa acgttgataa atcagagggt atgaaaatca tacccaccct cgacgaaaaa
     2221 tcagacgctg aatcccttgg ggctcaagag ggtatgaaaa tcataccgtg ccaaaacgtt
     2281 gataaatcag agggtatgaa aatcatacca gaacttaata ataatatatt agacactaat
     2341 agacacaata tagacactga aaaagaccgc ctacaagatc aattgttgtt agacaatttt
     2401 gagacaatta tgacaaacga cagcattgct acgtttgtcc ctgaacgagt attaaatttg
     2461 ataaaaacat tttcttcaag ttacagtgaa gctcaaaaaa ccgtccagac tattcataat
     2521 gcaaagaaaa aagctgaaat agaaagtgat atttcgatag tttttgaaga actcgatagt
     2581 tattatgtca atgcagaaca agaattatac acgacactgt taaaagccta tcaaaaatta
     2641 aaaaccgaaa aagtcgaaaa tatccagaac ctgatttttg tctatgtaaa aaattggttt
     2701 atcgaaaaac caatagctgc taaagtatca agtgaaaaac gtttgaatta tgcaagctcc
     2761 ccaagcacta ttacgaaaga ctggttagag tgaaacttta ctgacaaagt gattgttgct
     2821 tcatggagta acattaaaat taaaaatttt ttattattct aattatatta cgaatattac
     2881 aaaataatag ctattttaat agaatttata agttaaaata ttatgataaa aatcacaaac
     2941 gtagcctttt acgtcataag tgttaaaaga aataattaat ttcaaatata gaaaagggaa
     3001 cgtatgtttg catactcctt ttttttgagt tataataata cgcgaagaga gataatttca
     3061 ttatttaaac aagctaaaaa tcttgatatt acttcttttc aggcaatacg aatattattc
     3121 gcttacattt tttgtataaa tttaattgtc tgctatgctt gtgatgaatt gattttcgtt
     3181 ttgcactttt ggatgataaa tttggacaat tgaaaataca aaaaaaagaa aggcggtatg
     3241 aactcggaag gctggtaacc ttcgtcagcg ttcatacacg gcattaagat ttggccctta
     3301 atgcgttaac ctttcagtgt tacggtatta cccgcaatgg atttagtata acagatattc
     3361 aaaagtgata ccactttttt tggctgtgtt aaggttaaaa atacgtgata ttacgatgaa
     3421 tctatgccta agcataatgt tataaaaatg tccgtgtggc tctttgccgt atgacgaacg
     3481 ctgaaattag agggaacgca tgtttggatg cgttccctct tttttgtttg tcatgaacga
     3541 aaatcaattc tctatttttg aaaaataaca agaaaaactt gttaaaaata tttaaagaaa
     3601 ttgggtggtt tattttatgt catatacagg aattttgagt ctcaaagata tttgtcacta
     3661 cggtaaacgg tgtaccgcta cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa
     3721 aaccgttgtg cagtgtaaga aatatataat ccagaaagac aaagtctcag aggaaatgat
     3781 ttattacatt gggaaacaaa agcaaataat tttaaaagat cctatcccct taaaagagct
     3841 atatccaaca atcaaacatg tttatgacca aaacggtgta ctgattggtc gaagaaaaaa
     3901 tggagtcttg cgttgtaccg caaaagggat ggggcgtttg atcggctgaa ttgatcattc
     3961 tcataacttg tattttatcg tttttcgctt gcttgaaaat attgtcgaga cttctaaagg
     4021 aacttagagt cactagaaaa ataaggagta gacttgatct atcaacaatt cccttcgggg
     4081 agtgacgggg taggttttta cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcc
     4141 cttgtttgga tagtggtgaa atgaatttgt gtaaataata tgcacagagt aaacaagagg
     4201 gaatttagaa gttagacaag ttagaatagc gcctagatta atcatgagca gctactaagg
     4261 gatctaggct ttgacgcaaa ctcatggaat aaggagtagg tcttctcgta atggggagga
     4321 cgcacaagaa attgtgtcgt gtgctgcagt acatgtagat acttgcgaag acgttgatct
     4381 ttggatcaat cgagcattta ccgttttcta ctagggtttc tcgtttcgga cgccataaac
     4441 gagtcgattt attttatata tttttgagtg aacgaaaaac gataaaaata ttcgttatga
     4501 agtaaaacta atttagtaga tagcaaaggt ggtagaggaa tgattcaaaa atttgcgaaa
     4561 atgagtaaaa ctgcatggat tgaaaagctt gaaaatgact tgagtgtcat gcgattagct
     4621 ccaaagaaat tcaaacgaga gattgcagaa aaagaagcaa ttttgtcggt attgaatgcg
     4681 gtagacgata aatgtccagt aaaaattagt ttttcagata tagcaacaat tatcgaaggt
     4741 atttattatg gtgaagttga tgaagagata tcttctacaa aagatttatt agattttttg
     4801 gataaaaaca aagatacctt tatagtacta actgattatg aggaggttac aacaaatgaa
     4861 aaattatgat ccgaatagcc gatggggaac acatacgatt aaggtttctt tccaacgttg
     4921 ggattacaaa ggatttgtga cgtttagaag aggcggaaat tgtaaaggat tagatgtttt
     4981 agcattagac gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg
     5041 cttgctacct gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa
     5101 tggagacgaa ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagcgt
     5161 tgaaatcatt gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca
     5221 gataaaggct tagaaggagt cacgacgatt aataaaaagg tagtattacc ttaggcattg
     5281 agtaaggaat ttatttagga ggaaaattag atggcgcgac cagttttaga ggcgatggat
     5341 atggatactt tgacaaaagg aaggtatgta cagctgttag ctcgtggtta ttcacctaaa
     5401 gatgtattca aatccctgtc taaaggaaca gatatggaaa aagaaagatt acgaaaagaa
     5461 ttcgattatt ggagaaccca taatggaatc aaggatttga aaccagcacg gccagtaatt
     5521 aaacgaaaga aaaagataac ccaagactga agtgtagagc gtatgtgatc ataggctttt
     5581 ttatttttgc aaaaaacaag gaaggtagga aaactcatga attatgaaga aatcgaaaac
     5641 agaaaaaaag tgtcgaaaga aatggaagaa aagttgctaa aaacgatgaa acaaaaacac
     5701 cttaaaagat tatctgtcat gcaatatatc aatgatatgc agataacagg aaaagagaaa
     5761 gcttgtttgt taggttcaat gaaaaacttt gaacagttga gacgaactta tgtgaaaaaa
     5821 agttctaatt gtcaactatt gttagaagtc tcatgacatt cattaataga attcattttt
     5881 aaaacttttt ctatggaaat gagaaaaaga ttttttgttt tgtctgaaag gaggtagctg
     5941 gatgagaaaa tggttatttg gttttttagg agtcgcttta atcgtctttt gcagtgtgtt
     6001 tggctatgtt agctaccaaa aacatgaagg agaggtgttt aagcaaaata tagaaaaaaa
     6061 gatgcccgta gatcaaatca atgcacatgc aaagagttat aaggaggatg caacgaacgt
     6121 caataatgat atgtctttgg ggcaaatgtt gtccatacaa aaagaagcaa tcgaaatggg
     6181 cgtcaataaa caagtatttg cacaaattca gattcctgca cttggtttag cattgccaat
     6241 ttttaaaggt gcaaatcaat acactttgag tcttggagcg gctacttatt tttatgaaga
     6301 tgctgaaatg ggcaaaggaa actatgtcct agcaggtcat aacatggaaa tgccaggtgt
     6361 tttattttct gatatccaaa agttgtcatt aggggaggtg atggacttag ttagtaacga
     6421 tggcgtctat cgttacaagg taacgcgtaa atttatcgta cctgggtact ttaaattaat
     6481 cgatggcgtt cctgaagaga actctttctt gtctttgcca aagaaaggag agaaaccctt
     6541 attaacgttg tttacttgtg tttatacgtc acaaggaaaa gaaagatacg tggtacaggg
     6601 agagctacaa taacaaggtt ttaatcaacg cgagtcgttg aaatatgaaa tgaggagagt
     6661 aaaaaatggc aataaatcgg tatgtaaaaa aagctggaat gcttgttgga atgttaggaa
     6721 tcattgcagg ctgctttcag gggtatcaag tacatgcaga agatgtcacg caaaaaacac
     6781 caccagagaa ggtcaatatc acggttcata aattaatgta cgatcaagga acgcaattga
     6841 atgttgatat tgacgggatc aaaaacgatg gttatacgca cgatcaatat cctacaggtg
     6901 taacgaaata caacaaggca gattatggtg atgttgagtt tacgttagga aatattacgg
     6961 atcaagtatt accgagagaa gattctgatc taaccaacgc gaaagtggac gagattgtac
     7021 aagatgtaga agacaaggga tctaacagtg agtacgtcaa gaatgcaacc aacaaaatta
     7081 cttcagctgt agatgaaaat ggtgagatca cttttactga tcaaccagcc tatgtcaatt
     7141 ccaaagggaa tgtatatgtg gtttatgaaa gtaaatccgc tgctggatta gtcacacaaa
     7201 aagcaaaacc aatggttgtg attgcgccaa tgacagataa aacaggatca ggatttttaa
     7261 aaaatattca tttgtatcct aagaacattg tttctaagtt gagttttgaa ttaacgaaat
     7321 ttggtgacga tggcgcagac caaagcaaac aaaccctttt aaaaggggca aaatttgagt
     7381 tatacaaggg cgaacctgga aaaggaacaa aattgggtga tcttgtatcg gatgatcaag
     7441 gaaagctgac tgcgactgat ttgacgttag gaaaatacta ttttgtggaa gttccttcgg
     7501 aagttgtagt gggatcagat caagaaccaa cagcagatca atatttatta ggcgcagacg
     7561 ctcgcaacga tgcgcacaat aaattaacct ttgaaattac gaatgatggc gtgacaagtg
     7621 acttaaaagc ttcatacgta aactataaag caccagtgat cgataaaaca gtaacaaatg
     7681 gaacaggaca agaacattct ttccaaattg gtgacgcagt aaattatcaa ggaacgattc
     7741 atattccaac agacattgca ggtggcgcag acggtatcac agtaaacggt gtgaaaagcg
     7801 aaacttctcc ttacagtgta tttaaatggg gagatacagc aggacaagga ctttcttatg
     7861 tcgctgctaa agcaaatatc aaagtaacaa ataaagatgg atctgtggta ttaaaagaaa
     7921 atacagatta taaaatccaa aattcagaaa atggctttgt gatcgatttt atcgtgaata
     7981 atggccaagt aagtgatact gtagcaagtt tacacggaca agatcttcaa atgacttata
     8041 acatgtatgt aaatgacagc gcagctgttg ccaatccatt aacaaatagc gtggatttcg
     8101 tttataacaa caatccattt aatcaggaag aacaccacga aaaaacgaaa gctgacgttg
     8161 tgacttatgg tgcaaaattc ttaaaagtcg atagcggact atttggaaca ggaatcaaag
     8221 caacaccgct tgaaggcgca gaatttgctg ttaaaaacgc agaaggaaaa tattatggtg
     8281 gattagttga tacggataaa gacggtgtca aagaagcagt atgggtagac aatgtagcaa
     8341 atgcagcgat tctaaaatca gataaagaag ggcactttga aatcactggt ttaactgaag
     8401 gtgaatattc attggaagaa acaaaagcgc ctgaaaacta tcaaaaatta acagaagata
     8461 ttgcatttaa agtaaacaaa aactcattta aagaggaaaa tcgaatcact gttaaaaata
     8521 atcaaaaagc agctattcca ttaacaggta gtaatggttt ccaaacgtat gtattgatct
     8581 cttgcttgtt gctaggagca gggggacttt ctgcagttgt ttactttaag aagaaagcct
     8641 agaaggatca gctaatgatt attcgtaagc ccccaaaaag aagagtcatg cacaaactga
     8701 tgatattttt ttggttgctg tcggcagtag cagtctattt aattccagtt gtggaaacaa
     8761 atgtagcgaa atttcaacaa cagcaaagaa ttttagccat tgaaaatctt gaaaaaacag
     8821 attcttcttt ggatgttgcg aaaatagagt taggcgatcc tgttggtgtt cttacaattc
     8881 caagtatttc tttaaaacta ccaatttatg acggaacttc cgacaaaatt ttagagaatg
     8941 gtgtagggat tacggaagga actggcgata ttacaggagg aaacggtaaa aatcctttaa
     9001 tcgcggggca cagtggactt tataaagata atcttttcga tgatttgcct tcagtaaaaa
     9061 aagggcaaaa attctttatt aaggtaaatg aagaacaaca tgcctatcaa atttatcgaa
     9121 ttgaagaagt taaagcagaa gaattacaaa aaaattattt agattatctt atgcctgaaa
     9181 aagaccaaga taggatcacg ttaatgacat gcacaccaaa aggtgtcaac tcacaccgct
     9241 ttttagtgta tggtgaacga gtttccttca gtaaagaaga tttaaaacta cagaaaaaag
     9301 caaaaaatag gaaatcaatt tcattggatt ggcgattagc actgctattc gctttttttt
     9361 gcgttcctat tatttttatt tataaaaaaa taaggaggag atcggaatga ataagagaaa
     9421 atggctgttt gtttgtgtag cagctctctt ttctactgta gcttattcgc aactgtcttt
     9481 cgctgacagc agtgatagta gtaccactca aacaatagat aattcaatta ctgcaccaag
     9541 cgaaacggac agttcggaga atactacaga agaaacggca gattcaaata taagctttac
     9601 tgaatcaacg aatccaacgt cagaaagttc ttcagagact tcagaaaagc cgcaagacgt
     9661 agaagatacg caagtgatca agcaagccat tcatattcaa aaaattattt cttcgaatca
     9721 aatcaacaat caaggcagtc aagtagccca gcaagaaggt atcaatggcg caaagtttat
     9781 tgtctacgat atcacgaata tcttagaaga aatgtcacaa gatgataatg agaaaaatca
     9841 acctgtagaa ataattgagt caaaattgaa agatcgagca aaaaaacttt catacgacca
     9901 gttgaaaaaa gtggctgaag gagaaaccaa aacgattgat gatcaggaag gcgtgattga
     9961 attttccatt gaagtacctg caaacaaaaa acaagcatac tatatcgtta atgaatcaag
    10021 ccctgaaaac atttcaaaca gtgaagatat tgttttattg acacctgttt caaatgaaaa
    10081 aggtgaattt ttgacggatg tttggttata ccctaaatca gagaaatcag agccgaaaga
    10141 agaaattaaa aaagttgtgt caactggtgt aaagaagaac ttttttgaaa attgttggga
    10201 attttttgct caattatttt ttgataatta ggatgaaatg atgaaaataa taagaatatt
    10261 agtttttaat ctatcctttt tagccgcaac attattgtgt tgcggtttaa ttttttctca
    10321 attatcaatt tatccaagat atcaacgatt gttcattcat tttctaaaca ttcaatgtgc
    10381 ttccatgcca ttagaggtga ttaaaaagct cttgatcagt ccaattttta tggttagttt
    10441 ggttcttctt acaggattgg taacgtgggt attaggaaaa aaagaatgaa aagcttacga
    10501 tcgtttaaaa aaaatattag atggagggca ttatggaaaa taaaattcat tgcactacgg
    10561 gaagagtaat tactttagtg ttgtttttgt tccttcttct ttttgcgagg ggaactgcag
    10621 tccaggcctt agaaaaagtt gatccgagtc aaatcaaaga aaataataat ctggtgcttt
    10681 atcatgatag tgattcattg agaaatatcg aagtaactgg gatcaatgga tttaagatac
    10741 tagatgagta ttcaactaaa aaacaaaaag tacttgcttg gccaaaagtc aaagatttga
    10801 aaagtacgtc aaaaatcgtt gcccattatc aaaaagtagg tacttatcta ggaaaagaaa
    10861 ttgattgtga cgtgactttt tctaattttg tagcgcacgc tggggttaac caagacggat
    10921 tagctaaaac aattaatggc aaaaagtatt ataattattt gctctttgat aaaaatattt
    10981 atcgaggatt tttcatgcag tcaatcaatg tcatgaatgc aaaactagaa tttaagtatg
    11041 caggaacaaa aacaaaagta gctttgagtg aaccacagcc agaaattcaa tcaaaaatga
    11101 gatcgatgag agcagctggt attgatttaa acgatacatt tctatccatt tatagtttaa
    11161 atggacagta tcagcaacgt gtgtcttggt ataatgacaa taatgaatct gtcggtgaac
    11221 gtaatattga tatgagagaa tttgttgggt atgaaaaaat gggtagctta ccttattttg
    11281 tcacaacaga tacagcatgt gcagaataca aagctcctgc gttatcaaca aacaatttaa
    11341 cttcaaaagt agtgggagga cgtgcagaaa aggcttatag ctcgaatgat catttcaccg
    11401 atgttgtagg agctgatact tatcacagaa gtggtgtaac gtatacgctt caaggcgctt
    11461 ccccaacatt catgattggc gcaaatacga atagtatgat gtttagcttt gatactgcat
    11521 tgctatggac accacaacca tcgaagccta caaaagaagt gtttaacaaa gctaatactg
    11581 aagaggcagc acacaatatt gacaaaaaag tgattccaca aggatcagat gtttactatc
    11641 atattcacca aaaatttgat gcattaacag tcaacacaat gaacaaatac aaatcattta
    11701 aaatcactga tacctttgac agcaaaaatt ttgatatggt attggatggg aaaaactatg
    11761 atggcgcatt gtggtatgtt gaagcgaatg gtacttggaa aaaagctgat acaggaggaa
    11821 aattaactgt atcaagcaat acagtcactt atactgcttc tgacagcttt ctagctaacg
    11881 ctgcaaatta cggtagagat tatattttgc agctccatat gaaagcaaaa aatgatgcaa
    11941 aaggaatcgc acccaatgtg gctactgtaa cgtttaacaa tgatccgaat aaagggacac
    12001 aaagaacaaa tacagtagaa aattatttct ctcttaaacc aaataaaaaa gtggaacaag
    12061 atgggaaaga tgttgatggt cgaaatgatg gtaaaaaagg aacgcctaca gctcctttaa
    12121 atgcaggatc tgaagtacaa tatctagtca cacaaaaatg gcatacaaaa ggtgtagaca
    12181 ttgcgctcga tcattacaag caatttagta ttcaagatcc agtggaagct cgtttgacgt
    12241 ataaagaagg ttctgcgcga gtgatagata tgagtacagg aaaagatatt acttcagaag
    12301 gtacactaac ctatgatagc aattcaagaa cgctgaagtg ggaagcttcc gctgatttct
    12361 taagtaaaaa tcttttagat ggacgagaaa ttcaactgat atttacagct aaaactcctt
    12421 tgaatgaaga attggatatc gacaaccaag caaaagtttc agtagaaagt attgagaaag
    12481 caactaatgt agtaacgatt ggggtaaaac ctaacttacc tcagatcatt gtgccaaaaa
    12541 ctggatcgaa tcatttagtg ctaactgtta ttggaagtat attatttctt actttagcat
    12601 cattgggcta tgtagtttta aaactcaaat aaatataaaa acaaggctga gaatcagcct
    12661 tgttttcttt tatttgaaga ttggattcgc actaataaat acattatcta cgccaattct
    12721 accagcagag tcaactacaa aattatgacc taatccgaga atactttggt tattataaag
    12781 taaatttgca ttatgggcag ggctattttt ccatcctacc atggcatcga tagcaccatc
    12841 gtctgataaa aggtcatcaa tatacagccc agtttgactt atgttttctc ccttagcacc
    12901 gtagcagcct aagctttcca ataaatcttg gaaagtacca ccaccagggc gatagtgact
    12961 gaagctgact tgtaattctt tagctcgaat atctgcagcc tgttgaacaa tatcattgaa
    13021 ttgcattggg gcaacaccat tttgttggcg ataatcattt aaccaagcaa gttctttttg
    13081 acgcataaag ttacgtaatt cgtctaatga aatcttttta tatttgaatg tgattgtttt
    13141 attttgatcg acgttattaa tggatcgttg gccgttttta tccacggtaa cggtaggatc
    13201 gtcatttctg cacaagaaat aattttgatc agtcatgttt ttccaaggag tagcaaagct
    13261 atccccttcg tatactgttt ttgattcact agagagaaca gcgttggtat cagcatttac
    13321 atgattaaca gtcacattaa atttacgagt gtagttgaaa atataatttt gactttcagt
    13381 cacattgttt aaggttactg aatttgttgg ttctacccga tcgtctaaaa catatccttg
    13441 aatagaagga gcagttaaag tgacactgtc accgtgagtg acattgacta tctgttcttt
    13501 caaaatatta actcgtcctt cgtttttgta gttgttattg cacaacaaat tgatttgatg
    13561 cacttgatta taattgaatg tgattgttgt attacctgtg attgttttgc tttgagtatc
    13621 attaccaatc actttgtagc taaaattatc tttagcgcct tcgctatatt taaatgcttt
    13681 tgccttagca gtgtaagtag aaccagaagt tacttttgct tgatctgtag caatcacttg
    13741 acctgtttga ttgtcaatat ggttaatagt aaccgtatat tcttttggtg tttcaggttt
    13801 gtgttgcaac cctttaaatg cagcatcaag actattttta gcattattta cttgggcttg
    13861 agaagcctta gaatcgtcta gtactttttt agcattggat aaagcagtct gaaaattatt
    13921 ccaagattct tctgtaaaat ctcctttagc agttgatttt actcggttgt ataaagcttg
    13981 taattcagct ttattcacag taggaactgg ttttttcttt aatcctttgt aagcagaatc
    14041 taatttattt ttggcactat ccacttgttt ttgagtcgct tttgagtcat ttaacacttt
    14101 cttagcattg tttaaagcgg tttggaatgc gttccaggta ttgtcggtat agtcaccttt
    14161 tttagttccc ttaacgctcg tataaagagc ttctaaagct gatttattca ctttgggttt
    14221 agaggtgtca gcgccatacc aaccgatacc ttcgtatttc cagccatagt ctttggttaa
    14281 ccattgtact tctttccaac ttgcagtgta gtgatgtgag ccagatttta caccaggaag
    14341 gaaaaggcgg tagatcggtt tattattttt ttcggcagaa cgccaggctg gcccttcata
    14401 agtccagccg taatttttag tcaaccattt cacttcatcc caactagctg tgtaatggtg
    14461 atcacgaaga cctttattgt acaaacgata gacaagatgg ccaccgctag tcggtgcttc
    14521 ccaggcgggg ccttcataat ttccccattt tatctttact agatggtcac gttctttttt
    14581 gctagaggtg taaaaatgtt catgattatt tggattgtaa aggcgataca tgacgttagt
    14641 tgaagcagcg tcaacagatc cagcaagact aagtgaggca gcaaatgttc caatagctaa
    14701 aacagttttt ggattaaata atttcatttt ttcaactcct aaatttaatt aaaaatgttt
    14761 acatgattat tatatatcgg ctaaccgata tagtcaataa aaaataagaa aagccttata
    14821 taattttggc ttttcttatt ttatttgtta gttgaagtat taatatcaac gatttcttca
    14881 gccaatttat ttaatttcat agcatttatg aatctcatgt tgtctatact agagcgtttg
    14941 ttggcaaggt cacttactgt agttaagggt acgccagatt ctatggatat agaacgaact
    15001 gatttaccac tatcaaacag caaccattcg attttctttt tatcagcgta catttcaatg
    15061 ctccttcttg ttttttcttt attatagctc ttttttgtaa taaatcacaa tatcaagaga
    15121 aaaattttct atagaaaggt ggatttttat gagtattcgt tctccgtgta tccaaatgag
    15181 gtttgttgct actttcgtta tttgatatac taaaaataaa caacgaaaga aggaataaaa
    15241 tgaagaaaaa gcaactatgg tttgtctcta tgtttgcaat attttttatt attttaagtg
    15301 gatgttcaag taataagaaa tcggaagcta aagaagataa tagtttattg caaccaggaa
    15361 ctgtttggaa agaagaagta ggtggtctta ttcataattt aaaaattata gatgatacta
    15421 cctgggaata ttctgaaagt gtatggcatc cagatcctgt acaaataaca gttaagaggc
    15481 aaaaagacta tgaaggttta gaaagataca aaatagtaga ttctgcaggt attagggaat
    15541 ttataaacaa acctgattca ttatttattg ttgttcccta tgagaaggat ggcgtaaaaa
    15601 aaataatttt tcttggatct agcaaggatg agaagcgaac gaaagagaaa ttaattcatg
    15661 atggatcaga gttaaataaa tacaaattac aaaagactag tgagtgattg ctagtctttt
    15721 tatttatcct gaaggaggaa tcacagtggc aaaagttaaa acaccattcg aaaaagccgc
    15781 gtctaaaatc ttagaacgcc gtggtgtttc tgaaatacag tggaaaaaag aagttcttga
    15841 aaaagcacaa tttgacctat tacgaggaaa agataaggac ttagaagaat atatctatca
    15901 acgtgaacgt gaaaaacttg tattcgatga aattattaaa cattaaaagg agcgaataat
    15961 cttatgtttg aatcaattac aatgaatttt ttaactcaac cgaaagtagt agctgcagtt
    16021 gatattttta gagcattaca aactgccgca actagtttga aaaataatct gatgattttt
    16081 gctgctgttg cggcagtggc ttccattgct cttggaggta ttttcttctt ctttgggcga
    16141 agaggagctg aaaacgggaa gacacacgta ggttatgtat tgttgggggt aggagttatt
    16201 ttagctgccg cttctattgt agtttcaatg ttctcaatgt ttggacaaac cccacaagga
    16261 ctataaaaaa acaagtagaa ggagtaaaaa gtacgtggct actttttact ccttttttta
    16321 tggaaggaga atattcatgt tttttacgat ttcaggcaat gcaaaattgg ataaagagtt
    16381 aataagaaaa gcaacgaaga aagtgggaaa gcgtacttcc tttttaccga aaacaattaa
    16441 atattctgtc attgaaacgg aagaacagct acatgtgtta ggacaagtgt tagaacaaga
    16501 gaatcaatct tctgttaaat tgactctcac gttacatgat aaagaaggaa aaatagaaaa
    16561 ggctggcaca gaatacgttt ttggctcact ggattatcaa atttcagaag gtttttatcc
    16621 tacattgatt gatttaatcc gcctagatat atttaaagat acggatgaaa ccatgagtgt
    16681 ggaagagtct tatcgaaacg aaaaaatttt acaagtttta gaagaagagt tagaaagcga
    16741 ccaaagaaaa gtgaatcaag tgagtgaagt cgaagcaaac gaagaagtac catgggaacg
    16801 cccaatcttt ccaaaggatg aatcaaaaga aaaagagaaa ggaattattg acgaacaagc
    16861 tgacattttg actcataaat caatatttga ggaagagaac gaggtaatgg gtcaattgga
    16921 ggtagatccc tttgaagaaa caatggagga tgaagagacg gccgaagtag aagttgatcc
    16981 agttgaagct aatgaagacc caacatggac tgaaggggat tctcaggaat atattgaacc
    17041 acttatcagt gaagaagtag agaaaaatga aacagagata caaaaggcaa cggtatttga
    17101 ttatattttg gatcaatatc cgccagagca tgaatggatg aaagaaaaaa ataaattatt
    17161 tttaaatgaa ctttattcga aatatcaatt acctcaaacc tatcaagcat ttttagagag
    17221 taaagaagaa ttaatctcac agggtaaagg cacactttta gaacagttag agtctgtcca
    17281 atcaacaaat tggcatgagc ttgcacaaga agatttatta gctacttttg aagaacgtca
    17341 acaagaaaca gatcaagaaa ttaatgagta tgcgacggaa cagtcgtcga attgggagaa
    17401 agcaaaagag gaactaaata aagaagaaca gcgagtgatt gaagaagaag tacaaaaaat
    17461 taaagagcgg tacgaaaaga aacgtgacaa tgcgtattcc ttgtgtgtag aaaagatcaa
    17521 caattttact cagacgaatc aagaagcatt atcgaaagaa aaagaaaact tattaaaaga
    17581 acgtataaaa gaacgaaaag aagaatttta ccgagggttg cgtactgata agctaaggat
    17641 tagcaaagaa ttaaatgaac aactgaataa actctatcaa actacgactg aagttctgat
    17701 ggaaaaacac gagcagatcc aacaagaatt acaagcacaa attccaaaat ggaaaaaaga
    17761 gtatgaaatt caccaacaag aattgaaaga acaagaagaa aaacaacgga aaaaagaaaa
    17821 agagcgcgaa caattagaac taaaaaaacg tgaacaggat cttgcggaac aaaaaatggc
    17881 gatagaaaaa caacggctag agcaagaaaa ggaaaaagaa gcagctgctc gtaaggaacg
    17941 tcaagaacaa atggatacat tgcgacaagc acagttaaat tatctgacac atcctcaacc
    18001 agtagctgct gttcaaacgc cagtgaacaa ccaagcaaat ttaactcctt caccccagcg
    18061 ttcctttaac ggatggatgg tgggatgtat tgcaagttta agcttgcttc taggtggagg
    18121 aacagtattt gcttttaatc atatcaatca atcttcacag gctgattctg tagccacaac
    18181 ggcgtcaatc aaggaagaag cccaggaaca agcaagaaaa gagtatgaac aacaattaga
    18241 agaattattg aatcgtacca atcagtcaac aacagagtca agcatggaaa atagcaaaga
    18301 gagtgattct agtaaggcta aagaaggatc aagcgattca actgtacaat caaacacttc
    18361 cgaaagttca gaatcaaatg aggtgaaata atgcgtgtta gagaaacaac gaagcgaaaa
    18421 gacaaacgat tcaatttaga aaagaatagg tatctttctc atttctatcg ctatactccc
    18481 tcaggagaag agctaccaga aaaacatgac aaacgcattt cgaaaaagat tttttatagt
    18541 ggacttgtat acctcccttt agagtattta gtaacaagag taccagaagt tttcaaccga
    18601 ttggaaattg ttaagggaag cttacaagga ataaatctgt ttcaattaca ggaaatgcca
    18661 caggtctttc attttgattc agctggtttt tggaatccat ttactcctac aactagtttg
    18721 ggtacacgtt tagcaatttc gacagtttgt gtggttccag ctgtacttat gggattgaaa
    18781 atggacatgt ggtttcgtcc tctagcagat ggacaaaaag gggataatcg attaatgacc
    18841 ttaaaagaaa tccaacagat ttatccgcaa atacctgaaa caaaaactac ttttccaggt
    18901 tatggaggta ttccaatcac acattacaaa aaatattggt acattcaaac agatactgtt
    18961 aatacgtgta ttgttggtac ctctcgatca gggaaaggtc agattgaagt gttagccacc
    19021 attgacaatt tatctcgtgc agaaaaacaa agttcaatgg tcgttaatga tccaaaaaca
    19081 gaattatatg ttggtagtaa agatgaacta gaagctagag ggtatgatgt atatgccttt
    19141 aatatcaccg atccactgca atcaatgagt gataatccat tggcactcat cgtgaaatac
    19201 tggaaacgag gagacataga tactgcaaca cagttaacca atactttcac aaatacgatt
    19261 tattatgatg ccaacgcttc agataacaaa tactttaacg aaaacgcgca gaaagctgtc
    19321 aatgcgctta tttttgcgtt gttagaacaa gctgatcaaa caggagatta ctccaaattg
    19381 acaccgaata atctcgttga gcttctttct gagattggcg gttttaatta ttatccagat
    19441 ccagacaatg aattcaaaca gttgaatgcc ttagatgaat ttatgaatca gttgccacct
    19501 ggaaacattg caaaaaaaca atatggggca acgaaaattg gatctgataa agcgaaggga
    19561 aatattttat caacggcaat cacgggattg aatccattta ctctaacgaa aattgcaaag
    19621 atgacttctc aatcaacgat tgattataaa tcggttgggt ttccaaaata cttagatttg
    19681 aaattacatg aaagtctttt aaatcaacga gtcgtagtag aattttatca taagggaaag
    19741 aaatttcatg aagaacgtgt caaagtaggc tataaaggat tttgtgaaat caattttgat
    19801 tgtcatttag ttgcaggtga tcaagtttgt ttaaaatacg atcatcaagg aaaagaatat
    19861 gtggcttggt atgaattttc tcaaagagta ttgaaagacg aagagggtaa tatcgtttat
    19921 cggaaaaaac gaggagaaac ccatttgcca gaattagaaa aagaagccgt tctaacatta
    19981 gatgaggaga aaagtaactt attagtagag tctattcgga tgcactatac cgataaacca
    20041 atggctattt ttatgcttac acctgattat gatccatcta accatatcat tgttagtatt
    20101 tttcttagtc agttatataa agaattatct acgcaatgtg ttaagactaa aggagataaa
    20161 tgtcaccgca ggattcattt tattttagat gaatttggga atagtgtgac ctgtttagcc
    20221 taaggataaa agaggctagt tccaacgaac attggaataa ctttactatc gagaaatcaa
    20281 atgacggggt aacgccctga agggtttcca ctgatactgc gacatgcgtt agtaggatgt
    20341 gcatccaaac gcgtatgaag ctcgctgaag tcggcagaag ggtaccgtaa ggaaagacac
    20401 gatacgtatc taccacgcaa gtgctctaga ggtagggtat gtacctgata tgtcgggtgt
    20461 cctaaaaagt tcaataaggt gagaatgatt tgattatctg acaaacttgc gaatggaatg
    20521 tctgaaacga ataactcata gaaatgtgag ggggaagggg gatacgtcct ctttccattg
    20581 actcgaggtt gagtaaaaat gtgtttctat gaaaaacctt gcatggttaa aggctatgga
    20641 gtagtcaaca ggcaaaagca agcacctaag ttgaaatcta tggatagata gtaaggaaca
    20701 ggggaagcat ctagcacgga gggagcatac cgaagatgtg tttctaagga aaaaccgaaa
    20761 tcggttataa cttaggtgaa tagatgtgaa agtagagcca cgaccagtga aaatttcgta
    20821 atgaaattgg aggaacaggc tcaagtcgtt atttataata taagaaacct atttaaaatc
    20881 atggattctc gtaagactaa aaaggtcacg aaccagaatg gagcgtgata aaaccatgac
    20941 taacacaaaa ggaattagct taaagaacaa acaactcaga cacgccgaat actacgacat
    21001 gactgagact ttcgatgaat tgcacgcaat gagtgttgca aaatcaaatt ttaaaaatct
    21061 catgaaattc attattgatg acaataatat ctttctagcg tatagaaata tcaaaaagaa
    21121 taaaggaagt gcaacggccg gatacgatgg tgtcactata aaagacattg aaaaattggc
    21181 atgtggtgac tttttaacta ttattaaaag gcgatttaag gattacagac caagaaaagt
    21241 taaaagagta gagatcccga aaccaaacgg aaaacttcga cctttaggaa ttccttcaat
    21301 atgggacagg atagtccagc aatgtattct acaaatttta gaaccaatat gcgaagcaaa
    21361 atttaataag catagctatg gattcagacc aaattgttct acagaaaacg ccatagcaga
    21421 ttgtcttgct agaatcaatc aaagtaagat gaattatgtt gtagatattg atataaaagg
    21481 attctttgac gaagtaaacc ataccaaact tatgcgtcaa atatggacaa tggggattcg
    21541 agataaacaa ctccttgtaa ttattcgtaa gatgttaaag gctccgattg ttatgcgaaa
    21601 tggcaatgtt gtttttccaa ccaagggtac tccacaagga gggattttaa gtacactgct
    21661 tgcgaatata tgcctgaatg aatttgattg gtggatagct aatcaatggg aggaacgaac
    21721 tgtcaaagag ctgaaacacc actatcgaaa aaacggagca tgggataaag gaaatatcta
    21781 ttcgaaatta agaagccaca caagtttaaa agagatgtat ctggtacgct atgcagatga
    21841 ttttaaaatt ttctgccgaa caggagaaga agcccaaagg gctttttatg ccacacaaaa
    21901 atggctcaga gaaagattaa agctcccaat ttcaatggag aaatctaaag ttacgaacct
    21961 aaataaagct gaaagtgaat tcttgggttt ttcaataaga ctccacaaaa agggaaaaaa
    22021 gaaagtggct ttcacgtacg tttgtcgcaa agcagaagaa aacattaaaa ataaactaaa
    22081 acaacagatt aaaaaaattc aatacgctgg agcaaaaaaa aataggcacc gagcaatagg
    22141 tgactacaac atgatggtca tcggtatcca caattactat cggatagctt cacattgtag
    22201 tgtcaatttc actgagattt atagaagtgt taggacagta atagaagcaa gactgaaagc
    22261 tagaggaatg acgaaaaatg gaatctatgg acaagatcat gaaggatacc gtccgtatct
    22321 aaagtctaag caaatgagat atattgaagg ttttccgata cttccaattg gctatattaa
    22381 aaaaagaact ccactcaaca agcggagaaa tctaaataaa tataccaagg aagggagaaa
    22441 gctcattcat caagagcaac aagctataga aagctggaaa atcaagtatc ttgtaaaagg
    22501 ttttagtaac aataagaaat acacggtgga attttctgat aacaaaatat ctaagtttat
    22561 ttcccaaaaa gggaaatgcg ctatcacagg aaacgaactt ttgatggaag aaattgaatg
    22621 ccatcacatt aacccatatc atttgtccaa agacgatagt tacaagaacc ttgtcattat
    22681 ctctagagaa atccatagat taatccatgc aactagtgaa gaaactattc tgaaactgct
    22741 tcggttactg aaactaaatc actatcaaat tagaaaacta aacacgtatc gaaaaaaagc
    22801 agctaatttt ccaatatcaa tcaaaatgaa ttagatagga aacaaattat attgtaatta
    22861 acgatggaac gccgtgtgcg gtgaaagtcg cacgcacggt gtggaccggg ggaaaagacg
    22921 gagataatat caaactctta cctatcggaa ttgccaccaa tggataatat ggaaggaatc
    22981 atgacggtca cagctggtag aaacatgttg tgggatctgt ttattcaatc ttatcagcaa
    23041 ctttatgcga agtatggaga acaaaacgca gcgattatca aagaaaattg tcagacacat
    23101 atttatatta tgtcgacaga tgataatacc atcgaagaat tttctaaaaa agtggggaat
    23161 aagacggttg aacaagagaa cagtaccatc aattcattag gtatgaatac tcatatcaat
    23221 cgcaatgttg attcagatcg tatcttaact cctgaaagaa tttctacttt tttagaaggt
    23281 gaaacgattg tactcgctcc tttaaaacga caagatttga aaggtcataa aatacggccg
    23341 tatcctattt ttaatcatgg ggaaacgaat cttccttatg cttatcaata tattgaagat
    23401 ttcaatccat cgtgggatat caatgatata gacatacatt gtacacatgc ggacttggat
    23461 cttaaggctt tacaaattga ttatgattat ttcctaccag atgaatatgc tagaaatctc
    23521 tatcatggac tgcatgatca attagaagaa aaaaacgaag aaaatatgtt ttataaaatc
    23581 gttcaatctc ttgagaatga gacggctaaa aaattgttaa ttcaatttta cgaagaacaa
    23641 gcagcagatc gacttcaaga atatgttgaa aagttgatca aaaataaaga aatttctgaa
    23701 atgattggga aacggttgtt attggaatct gaaaaggtgg tgaaagaatg atcattggag
    23761 gaattttttc tggcatagcc gactggtggt caggcttatt cggagaaggg gatgcaaacc
    23821 ccaaaaccgt aacgaaagtc ttacaagatt atggtaatta tctgcagtat caagatgtat
    23881 ttagttggat ttggaacact tttctgtggg gattgattaa aggattatat aatctcaata
    23941 ctttactaga aaaaaccatt tatcaaagct ttgatttaaa agacttattg aacgccgctg
    24001 gggtaaatgc actatttcaa agtttgatta gtaaggtatt ggctcttttt tgtgtcgtca
    24061 cattaattta tttaggcttg aaatttttta tgagtaaaca cccaccaaaa gtcaaaaata
    24121 tcttggttaa tttatttatg gccatgatct tgatttttgg tgggagttct ttaatcgatg
    24181 aagggttaaa tatcagtaaa agcttttacg gagacgtcac tgcagcaaat aaagcagata
    24241 aaacgggttc acctgctttt caaattattc aaaataatgt gatcgatgtc agtacattac
    24301 tagcaactga cccgaataaa gtagaatccc tgccaacaga caaaagaaat gctttaacag
    24361 cgaaaaattt taaaacagcg aatatcaatg ggattattac tcctaaacaa gctaaagaaa
    24421 tggcggataa agataagagt ggtttatcag atttacaaaa ggatcggtta agagcgttac
    24481 aataccgatt ggaactagat gataatggga aagaaattcc tgttcaaatt agtgacgaag
    24541 gcttagcaaa atatgtctat acttcagggt atcgtcgata cagtagtaaa ccaggtatta
    24601 tcttagctgg tgaatcttct ttggcggtgg cctatttatt tatcctattt acgatcgtta
    24661 cttgcattat tgagctggta tttaaaaaat tctatttagt gattgccgcg tcaacggact
    24721 ttgagacagg ccaacggatg aaaagtgcga tagaagatat ttctcaatcc ttcttgttat
    24781 tggcgtttac gattttagaa ttacgaatct atacattaat gctttcaggt atcggtgatt
    24841 tgcatgcggc aggaaagatc aatggattct tgtatgttgt tgctttaatt gtgctaacta
    24901 ttgcgctatt caaaggctct caatcggtta cgaagatttt cggtgttgat acgagtctga
    24961 aaaacggcag taattctctt cttagcatgt ttgccttagg aaatattgcg aaaaatgtgg
    25021 gtagcggagc taaaaacctt gcaagtgctg gtaagagtgg tttaagccat ttaaatgata
    25081 ttcgtaaaaa tggatttggc catcgaaaag atgttacccc tgataacggg gaagaacaat
    25141 cagacgataa agctacaact gtacctaata gtaagaaaac agtttccgaa atgttcggga
    25201 aagcgaaaaa tggtgtttct aaagccgcag aaggtcttgg ttacgtcaat gaacgtgggt
    25261 taaaaggaac agctgaagat cttacagaaa aagccaaaga caccttagaa gagaaattag
    25321 acggcacgag agctaaagaa ttggctgaag ctgtgaagaa tccatccgaa gcactagaaa
    25381 aacaaaaaga aaaagcttca gaagtcaaag aaggactaaa agatgcgtat ggtgaaggac
    25441 aagttaatgc agcagtaaaa gctaatacaa caaccgaaaa agaaaatcaa gaaggtatag
    25501 tgattccttc agtcaaagat caccaagaag cgttgcactc taatgaaaat tcgattgaag
    25561 agaaaaattc catagaagaa agaaattcag aagaaggaaa aaatggacag ttaccaaaaa
    25621 ctgatccaga acaatatcgc tataaaccta acagtgacct tgaaaatgag aagcgaattt
    25681 cagatttatc aaaagtaaat caagaagaca aagcagaaaa tgagggacag ttaccaaaaa
    25741 ctgatccaga acaatatcgg tatagatctg ttaactccga aaatgaaaaa cgcatttcag
    25801 atttaccaaa acgaaatcaa gaagtacaaa cggatgagga ttccatcgtt ctgccaaatg
    25861 ataatggaat cgaagttgga actgaaaaat caacgaaaat tggtttacct aaggcacaaa
    25921 atttaccaat gaaagatagt cgtttgaatc aattcaagga taatgatcaa agttttgttc
    25981 atcaatcacc tgcaggtact gttcaaatga aaccaagtcg tttgcctgaa aatggaaatc
    26041 tgacaactgt ttcttacaat ttatctgaaa gtggtgagac agggaatgcg tccgttcaaa
    26101 atgttgtgac aagagaagct gcaccaaaac ctattcaaaa cgttcataca ggttacaagc
    26161 cagcaaatgt ggcatttact gcaccaacaa aaataaatgt gacaagagaa acaaaaaaca
    26221 ggaacaatgc attgaaagaa caactattga gggatatcaa acaggatatc aaaccataaa
    26281 aggcctacaa gttaggcctt ttttctatgt atgaaaagga gaaatcattt atggataaat
    26341 atagtaacat gaaaaaccct ccaagattta gtggagaatg gaagtttttc gcttttttct
    26401 ttttagatct attaacgctt ggtggctgct ttttttgggc gaaaatggtc aataatcttg
    26461 tccacttacc actctttttt gcactcttga attatggctt atggattgcg atagcgttag
    26521 tgattgtttg gcgaccctat aataacccag gtcaacgaca aatttttgcg attatcgagt
    26581 ctattttttt tgcggacaag aaccattatc atgcgttaga tcctaaccga aattatcatg
    26641 gtacgtataa ggaggatgaa taaatgcgag tcaaaggaca aaattcagtt gaaaggaaat
    26701 ccattttgca gtttggaaaa ccagaagagc gctctatctt ggacttattt ccgtataaat
    26761 cctgtacaga agagggagtc ttaattacta gagaagatca ttttcaacgt tattatcgtg
    26821 tagtttctac agacgtggaa ggattaaatg aacaagagaa actagaacga atgaatcagt
    26881 tgaccaccgt catgcgtacg tatgtgccaa caattaagtt agttagtttg accacagaga
    26941 cggatctaac ggaacaaatc gtgcaaaagc ggcaattatt agataaaaat cgtatggaac
    27001 agtccttagg aagaaatcta caacgattaa aaaaatatga aaagaaatta gtcgaagaaa
    27061 tccaggaatt gaaacgagca gaacaagaac gtcctgactt aagcttcttt ttcgtcattg
    27121 aaggaaagac aatcaaggat ttacaaacca gaaaccgtca gttaatgcga tctagtggca
    27181 ttttagggtt aaaaccactc tacaaaaaag aattgatcaa gattctgtat cgaatgaaca
    27241 atatgaatga tgagtaggaa tggagaagag agaatgaaat atccgttgat atggttagaa
    27301 aaagatgttc cgaaggaaga gaccactaga aaatttcctc acactttaag cctgggtaag
    27361 ttgggaaaag ggcaatcttt taaccaagta aagaatcaaa caagaagagg tgactgtaca
    27421 tgttagaagc aattaaaaca gctttttcac cacaaaatga tcaaaaagta cttgatccat
    27481 taaagcaact aggaaatcgg gaaatcgaaa ttttaaaatc caaagggtat gatttagatt
    27541 ttttaaaaca agtgatgcca caaggtgggt taaattttga tgaagaatat gtgacgtatg
    27601 gtaatggtta ttcacgatgt gtgacagttt atcactacac aaaaaatcct acgctttttt
    27661 ggttggccaa tctcatgaac aatcctcata cagtggccac actcgatgtt agcacagatg
    27721 aaaagcaaaa agtgattgat caaatcaatc gtgccttaga tgaattaaat gatcgatcag
    27781 ataatgaacg aaaagcgact gaccgaaata aaagcgcgga agaatacctg gaactagcgg
    27841 aatatgctag aaaattgact tctaatgggg aaatttctaa gcaagtcaaa gtgagagtac
    27901 atgtttacgg aaacacgatt caagaagtag atgaacgagc gcaggaactg atcgaaaatc
    27961 tcaaagggat ggattatcgt gcggtgactt atctgcataa aaccaaacga gattggcaat
    28021 cgatgtttac catgttcgat gaacaagctg aatggttcgg aaatatcaaa gggcaatcac
    28081 taccatcgtt aaacattggc ggaggtttcc cgttccacca ccaaacgcta aaagatccag
    28141 gagggacaca atatggggaa accatgacag gcggcccatt tgtctggaat gcgacgtata
    28201 aaaatagtgt acggttgtct actaatacct tgcttctagg aatgatggga gctggtaaat
    28261 cgaccgttct taaaatgatc gcggaagccc atttagctgc aggagacttt atttggggct
    28321 ttgaaaaggg aaaagacttt attcctttct taaaggaata taacggtatt atggtgcgtt
    28381 tagacggatc tgacggaatg atcaatcctt tagagatatt tgccacacgg acgtatgatg
    28441 aagcatccag tttatatgac gatggatcag tcaaagattt gaagatcaat gaagcagcgt
    28501 cctatcaaac acacttagac aaagtggtct atcaggtaca gttagtgagt cctcagctaa
    28561 aaggaacgat gaaagcagaa tttaagacct acttaaatcg tttttatgaa gagtatggaa
    28621 cagtaccacg cggctttact tcctcaaatt cgcgttcaaa tactgatacg caagtcacag
    28681 ggaaagatcc agaagcttat ccgacgttca aagaattttt agacttttta ggacaactgg
    28741 aattaccagg tgcttcccaa gagaaaaaga atcgaaaaga agaaatggaa tccatcgtag
    28801 aatccttatg tgagacgtat ggcatgattt ttgatggtca cagtacgatt cgacaccttg
    28861 accaacaaca gttggtcttt tttgacattg actctattac aggcttagat cgaggggtac
    28921 aacaatgtca aatgtacatg gctatgacgt tgatttggaa tcaggcattg attcaaggaa
    28981 gaagacaacg acgtttactt aaagaaaaac aaatggaaga acaagacttc aaacgcttct
    29041 tggcgatgat tgatgagtgc cataatggtg cgacctgttc tgcagtgaaa agctgtgggt
    29101 tgcaagtagt ctaaaaacta ttgtaataac tcttataacg agaagtcaaa tgagtgggta
    29161 acgccacaaa gggcttccac tgatactccg acatgcaaca agtagtttat gcagaccaac
    29221 gttgtgtgaa gctcggtgaa gtcggctgaa ggataccgta aggtaaaaga aatagtgaat
    29281 accacgaaag ttctttagag gtaaagggtg tatccgataa gtcgggtgtc caaaaaaact
    29341 taatatggtg agtatgtaca aacgtactga cgaactagcg aatgtactgt ccgaaaggca
    29401 tagctcctag aaatgggaga gacagtgagc aaaaaatcac tcattgtgct aacttgtggt
    29461 tgagtaaaag tcgttgttat gaaagaccat gctgcgttac aggcgtagga gaagttaggg
    29521 ggcaaaagct agcatctaag ttaaggcatg tggatagata taagggaaca ggggaagcca
    29581 tcaacatgga gagtgcatac tcgatgaagt ggtagtaaga aatatgtgaa tgacaaataa
    29641 cttactttag tgatggtgaa agtagagtca cgactgatga aggttctgta atggaactgg
    29701 aggaacaggc tcgattcgtc tgtaaaagtc atgaaacccg ttcaaccatg ggattctcgt
    29761 atgactaaaa aggtcacgag ccaattggag cgtgataaac catgacaaaa gaaacaagtc
    29821 caaaagatag gaagttgcgg catgcagaat attatggcat gacggaaatc ttcgataaga
    29881 tatactccaa aagtttgaag ggagataatt tcaagaatct aatgcagatt atcatttctg
    29941 ataacaacat tgtcctagca tatcgtaata tcaagagaaa tcacggtagt gtgacaagag
    30001 gagaagatgg agtaacgatt aaagatattg aaaatctcaa ccgtaatgaa ttcgtagaaa
    30061 ttgttaggaa gcgattcgca cattataacc ctcggaaagt aaggcgtgta gaaattccta
    30121 aatataatgg taaattaaga ccgttgggta ttccatcaat atgggataga atcgcgcagc
    30181 aatgcatctt acaagtatta gaaccaatat gtgaagcaaa attcaataat cacagctatg
    30241 gtttccgccc aaatagatca gcagaacacg caatagcaga ttgtatggcc cgaatgaatc
    30301 aaagtcacat ggaatatgtg gtagatgtag atatcaaagg tttcttcgac gaagtcaatc
    30361 atactaaact catgagacaa atctggtcta tgggtatacg agacaaacag cttctcttaa
    30421 tcattaggaa aatgttaaga gcacccgtag tacttccaaa tgggaagttg atatacccaa
    30481 caaaaggaac accacaaggc ggaatactta gcccattact tgcgaacatc aatctcaacg
    30541 aatttgactg gtggatagca aatcagtggg aggaaaaaga tgccaaagag ctaaaacatc
    30601 attttaggaa aaatggagct tgggataaag gtaatatcta tcacaagctc agaaagagta
    30661 caactctaaa agaaatatac ctagtgagat acgcagatga ttttaaaatt ttctgtagaa
    30721 attataatga agcgaaaaaa gttttctatg caactaaaat gtggttacag gagcgtctaa
    30781 agttaccaat atctgaagaa aagtcaaaaa tcacaaatct ttcaaaagaa gaaagtgaat
    30841 ttttaggctt tacgatgaaa ttagtgacca aaggtaacaa aaaggttgtt aatacgcata
    30901 taggtacaaa agcacaaagc atgattaaag tgaaactaaa aaaacaaatc aaacgaattc
    30961 aaaaaagtcc taatagcaaa gataccttta tctatattgg agtctataac agtatggtta
    31021 ttgggattca taattacttc aaaattgcga ctcattgtag tgtagcaatg cgaaaaattg
    31081 caagagaact cagaccaagt tttgaaatac gactacgaga acaaggaatc tcaaaagaag
    31141 gacaatacgg aaagtacgaa ggatacaagc cttacctacg gtcaggacaa atacgatata
    31201 taagagggtt tccaatatta ccagtagggt atattcaaca cagacatccg atgtgtaaaa
    31261 aaagaaatat taataaatac accgaagaag gtagggaagc cattcataag aagcaacaaa
    31321 ccgtagaaga atggaagata tcgtggttgt gtagcaatcc agtgcttagt aagagagcaa
    31381 cgattgaatt tgcggacaat cgaatttcaa aattcatcgc tcaaaaggga agatgtgcag
    31441 taacaggtga ggagcttatc ttatctgaaa tgcattgtca tcatattatc ccttatcatg
    31501 aaagcaaaag tgatagctat gaaaacctag tgattgttac tgaggaggtt catcgggtaa
    31561 tacacgctac acaaagtgaa acgattgagg aacttctaaa atatctaaaa ttaaatccaa
    31621 aacaaaaaga aaaactcaat gagttgagat taaaagttgg taacgaagaa atatcttaat
    31681 aaatatttgt aggacgggaa aacagaatgt cttttataga cgagggaacg ccgtatgcgg
    31741 tgaaagtcgc acgtacggtg tggactgggg gaaaagacgg agataatatc aaactcttac
    31801 ctatcagtat cgattaatcc agattttatt gaaacggtaa attatgtcac aaactttcaa
    31861 cgagaaatgc gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg
    31921 gtgccagaaa atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct
    31981 tctacgaaga tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtt
    32041 ggtaaatcaa tgacgaactc agaactagaa tccattcctc aacaaaatca aggagacgct
    32101 gtgatcaatt ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa
    32161 ttgaaattgt ttgatggtgg aaagtaactt cttgtatttt ggtgtataca agtatatact
    32221 aatgtgtgag agaaggaggg attccatgtt agtaaaagaa atcgaaatga aaaaatgggg
    32281 aaattcacaa ggtattcgtt ttggaaaaga agaattgtca gttctaggag aaactaatac
    32341 tgaaaattta aaattcgaaa tggtggtaac agaaggaaaa attgttttaa ctcctaaaaa
    32401 taaaaagcca gaaactttag atgaattgtt cgccaattat gaaggagaac ccttaggaaa
    32461 agaagacaaa tatgaatggg gaaatatgca aggtagggag atcatttaat gaaaaagaac
    32521 tatcatgatt tatcgcaagg agatcttgtt tatattgatt taaatcctac caaaggacat
    32581 gaacaacggg gaaaacgacc atgtattatt ttatctaaac ctaataaata tttgaactat
    32641 atgattggtg tcgcaccgat aacaacaaaa gcgaagcctt ttcctgtaca tgttgatttg
    32701 aatggtacgc aaaaaataaa aggacaaatt cttttggaac accatcgaat gattgacatt
    32761 gagagtagag gttttcagtt tgtggaagct gtgccaaagg aaattttaga agaatgtatt
    32821 gaaaaaatta aattatttta ttaaaagcag cgaagaataa ttattatttc ttcgcttttt
    32881 tgttgtttaa aattaaaaag ttaggagtac tgactatatg gaaaatgata caaatatagt
    32941 tatggaacat ttgaagcgtc gtgcaaagcg acgcttattt ttgtggttgt ttggtacttc
    33001 tgcaggtttg attactattt tgatcactgt gttcgtaacc ctttttctaa tacttgcggc
    33061 gggttcgatt gataattcgg attccgattc aagtagtggt ggcgaagctt ttacaggaga
    33121 gtattcggaa ggcttaccga tttataaaga aatcaaagga agaggccctt tttctgatga
    33181 gattgcgcaa tatgccgtag gtgcagcagt gaaatataaa ttattaccaa gtgtgattct
    33241 ttcgcaatac ggttatgaat cagcgtttgg tacgtcggcg tccgcaagaa atgatctcaa
    33301 ctattttggg attacttggt ttgatggttg tctgtttcct aaaggaactg cacgaggaat
    33361 tggtggcatt gaagggggct ggtacatgaa gtttcccaac tcaaaagctg cattctccta
    33421 ttacggcttt atggtagcca cacaatcaaa ttttaatgca tgtgtaggaa ataaaagccc
    33481 tggcgcaagc ttattgatct taggacgagg tggttatgcc gctgcaggaa ttactgaaga
    33541 tagtccgtat tatacaggtt gtatgtcaat tatcacttct aataaattaa ccgaatatga
    33601 tgaattcgcc atcaaacatt ggggtgaagg tggcaataac aatggcacaa ttactggtga
    33661 atggacgaat ccattccctg gcagcagttt agataaaagt tccttcagcg gtggtcaatt
    33721 atttggaacg aatccaggcg gtgaattccg tccgaacggc ttccatgatg gattagattt
    33781 tggttcagtt gatcatccag gaagtgagat tcatgcggtt catggcggaa aagtcgtgta
    33841 cgttggcaat cctggtattt caggtttggg cgcgtgtgtg atcgtgatta attacgatgg
    33901 cttgaatatg gtgtatcaag aatttgcaaa tagtacagga aattctcgag tgaaagtagg
    33961 cgatcaagtg aaagttggtc aagtaattgg gatacgagat acagcacact tgcatttagg
    34021 atttactcga atggattggc gtcaagcaca aggacatgca ttcattgatg atggtacatg
    34081 gatcgatccg ttaccatttt tgaatagcag taaaaaatag atcaggagaa aaaatatgga
    34141 aaataaaacg ttaaaaatcg tcttaacagc tgcaattagc gttagtttaa tcggcaatat
    34201 tgcgttgttt tggcagctga aagaggaaca agcagcaaat acctataaaa ttgaagaagt
    34261 ggctaaaaac gcgtctgaga agctcaaaaa aaattcctct gaggcacagg cgaagatcga
    34321 caagttaaat caaaccatca atgagaaaaa ccaagaaatc gatcagctga agcaacaaga
    34381 tggcacaaaa gcaaaagagg aagtaactga agcacaaaga aagacggcag aagagttcgg
    34441 tcaattggcc attgataaat cattaagcag aaatgaatta acggaaaaac taaaagatgt
    34501 cgcaacccaa gaagtgatcg acaaattaag tcctacagac gatgatcacc aacatgatga
    34561 ttacggaagt tactccttta cattaggtga cgtgcaaact tacgctcaaa caagcagtgt
    34621 aaaagaggaa caaaattttg tcgtatttgt tgattataca atcggcaatc cgcaattcaa
    34681 agatgtcaaa ccacaaaaaa taaaaggtgg attaactgtc actgaaaaac aagtagatgg
    34741 tcaatggaaa gtcatagact ttagttattt cactcgttag gaggaagaaa atgagtaaga
    34801 aaaaaggaga aagacaacgt ttcaaaaaac gaaaaagtta tcttcaatgg ctgggaatct
    34861 ttatgattct cggctttttg attcttgcta gtccgattta cacgcatcag aaggtagaca
    34921 taccagatga agtaagcacg aacgcctttt taaacacgaa ggaactaacg atggtttcaa
    34981 aagaaaaagg agcgaaccag caattagttt ttgaatttgc aatcgacgat gaagatcaaa
    35041 gcttattaaa agaactggct aatcttaatt atcgcgtaga agtaaagaca gctaaagggg
    35101 attatcaagc aatacgagcc aaagtgatca aggtgtctga tgattatttt gcagtgaagc
    35161 taacgcatgt accagaagaa tatatcgcca tgcgtttaac cattattcct gaaaaaattg
    35221 atccaaaagt ggatatgcaa gaaccacaag atctgattta ttacgtgcac gaagataagg
    35281 ttaaagatca agtgaaagat gaagattatg aacaacacgc gatcaattac aaagtgaaag
    35341 gatacaagaa agaacaaaaa gcagctcaaa aacaaatgga atctttccaa gcaaccattg
    35401 atttgaatga agaattagtg aagaagctaa aagatcaatt gccttatcaa gtcgcagatg
    35461 atcaggaaaa tactgaaaac aagattaata gctaccagca agaaattgaa acatcgaaaa
    35521 cgcaaatgaa agatcaagaa gagatcattc aaaaacttca agaaaaaatt gatcgtatga
    35581 caaaagaaaa gatttagaag gacaggtgga gtgaaaaaat gaagcgaaca aacttggctg
    35641 acaaagatac tttcgctgag cagaaagtat tgattaaagc ctatctcaaa gttgtaaaag
    35701 ctaaagaaat atgtcgagaa gtgaatttat ctaatacaac aatatctgag ttgaagaatg
    35761 gtcgaaagaa tttagatact ttaaaattca gatcatttga agctttgtat ttagctgcta
    35821 aaaaatattt tacagctgat aacaaataaa aaacaggagt attttatgtg aaaaaagtat
    35881 ataaaaaatg cttatgaatc agctatatca ccttaaccat ttgttaatga gatgggagaa
    35941 aacattaacc acgattctaa cgcaaacatc aagcacataa aacatttaac actcctcctt
    36001 tctggctgaa gatttcaacc aaacaggaag acagcgtatc aattatagca tacacttttt
    36061 cttaaattca tttttcatat gacaaaatat ttccttctaa tcgacaaagt tagaaggatt
    36121 ttttattgtc taaatacaca aataacctta atttataaag agcataagga aacgtgtacc
    36181 cactttcaaa ataaagtggg tagataggct gtgcctatca cgtttctgaa aaaaataaat
    36241 gaccccaaaa ttttcaaatt atgtgtaggt ttatgggtag caaaaatatg aatgtgggta
    36301 gcacaaaagt tcatttgtgg gtagtaaaat ttaaatatgt gtagcaatgt gtgtagctac
    36361 acacattgct acacacgtta taacatatag tcaaaaggag atatttatgg aagtaaaaat
    36421 aagagatatt gatgaaaaaa cgattcaaag aattgaccga agatgtattg aattaagtga
    36481 acgtactggg actaaatgga gccgaaatcg atacctaaaa gttttgatcg aaaatgattt
    36541 tgatcacgct cttctggatt ataaaaaaga tcaatttgat cggttgttag aaaaatttgt
    36601 ggatattcaa acttataata cgaaaatttt agaagaatat attgcaacaa ataatcaatt
    36661 aatcgccttg ttaattgaac agtaaaaata atattgtgaa tttataaaag gaggaaatca
    36721 actttggcga aagcaacaag aaaacatatt tatctttatg atatgcatat cgaagtactt
    36781 gatgagataa tttctactca tgacgatata tccaattata gtgaagcagt tagacatttg
    36841 tgtatgatgt atgatcccaa aactgaagaa aagataagtc ccagtcaaat caaactaaat
    36901 gcaattggaa aagaagtttc tattttaact gaaatggttt cggagtttgc agatcttcat
    36961 ttaaaagata caggaatatt aattggtaca aattcaactg tttatcaaga agcgaaagag
    37021 cgtgtggaag gcaagataaa agcaaatcaa acgaagaaat attctcctaa gataaagaaa
    37081 acaataagcg aatcagtgac tacaaaaagt gaagtatttg atccaacaag gtttttaaaa
    37141 cgataaaaat tagaaggaga acgtgatgag taaatcacct gcagtcattc tcacttgtca
    37201 atttaccttg cccaataaaa aatctttttc aacatacatt gattatatga caagagaaaa
    37261 agcgctggaa gaaatggaac ggcgcacgct cgaagaagaa caggaactgc aacgaatcaa
    37321 gaatgcttta gaggattttt atattcctga aggagaaact ttttcggaga gtaagacgga
    37381 taaagaattc agtgaaacgt cgaatgaagc gcaatcgttg atggaatatg gaatcaattt
    37441 tgacaagtta gaggaacaag attttaccaa atatctttct tatatgacgc gtcactatgc
    37501 gttagaacaa aaaaaggaac taacggaaag ggaaaaaata gaatatcaac gtttgaatca
    37561 agcaatggaa aaatatcaag cagaaccaca caaaaaaact tcaggaactc ttcctggagt
    37621 tttttctata tcttcagacg aagtaaaagg aagtgatctg aaggagatta agcagatctt
    37681 ccaaagaggg caacaaaaag gctcaatcat ttatcaagat gttgtttctc atgataattc
    37741 gtatcttgaa aaaataggat tgtacgatcc caaaacagat actttagatg aagttggact
    37801 aaaagctgct ggaaggaaaa tgatggagac gttgtttgag aaagaaaaac tgaatgatac
    37861 gggatattgg atggctacca ttcaccgtaa cactaagcat attcatattc attttgcagt
    37921 tgttgaaaaa gaaaatacgc gtaaaccata cactgaggtc gaaaatggtg tgagttatat
    37981 cgtaccgaaa ggaaagagaa gacaagcaac attagacgca atgaagacca attatgtgca
    38041 tgaattagaa cgtttttctt atgaaaagga tcgaatgata ggcatggaga aacgaaattt
    38101 attaacgcgg aaaagtgatt tgcgtaacag cttaacaaaa gtggtaaaag agccagtacg
    38161 ttatgatcga cacgcaatga acttattaaa tgaagtatat aaaaccttac ctgacaaacg
    38221 ttcggaatgg aattatgggg atgaaaatcg aactaaactt tcaccataca caagagagaa
    38281 actcgacgag ttaacccaat atgtgttaac aaaagaacct gaataccaag aatatataca
    38341 gatttcaaaa gcattgaaag aagaagcaaa aagtctttat ggggaaagca agagagaatc
    38401 aaaggatgca gagaaaaatg ctctctttga tttaaaaaag cgcacaggaa atgccatcct
    38461 aacagagctg aagagacagg atagtcaaat aaaaccatta atagaaagtg ttgatcagac
    38521 gcaatctatt tacaatgaac gatcctttcg aacgcttaaa caattgccaa cgaatgaata
    38581 caaatatagt tacgaagaat tcatgaagcg caggaaacaa ttccaacaaa gagttgtcac
    38641 gcagcggagt ttgcgtcaat taaatcgaac gattaatgcc catgaagaaa aataccacgc
    38701 aagtaaagca tacgaagagc aacaacgaag aatccaaatg gaacaagaaa gacagtaaag
    38761 acagtaaaga cagtaggagg aatagcaatg aaacaatatt tagatcaatg gaaagttata
    38821 gaaggatcat taagagaaga acgaatcgaa caacttcccg attgtttaga aaaagagcat
    38881 ttgtttcaga taagagaaat gttgataaac gaacagtttg atccaaatca atttttagtc
    38941 gttgagtacc cagctactgg tgtgtactgt tgtaatcatg tgaagggtga aaaatatttt
    39001 atcattcaag aatatgaggg caagttagcg ccttattata ctacttggga aatgaatgaa
    39061 gaggggatca ataacttccc gtgtaaaagc attgaagagt ctatttcact cacagaatgt
    39121 tagttgttaa gtgaataaaa gaagtaaaag agtcctgaac gtgattgtcc aggactcttt
    39181 tttttcactg aattgttttc cgccaattca ttgagtggtg cgatttccgt ctacattata
    39241 tcaaaagaaa ggaggaagaa gaaatggctt attcaacgat tggagttgtt gttgaaaaaa
    39301 gcagagacaa tcttgttttt gtgacagaaa ttcaaacagg cagagctttt gtagtcacag
    39361 acaaagcggc aaaagcatat caaagtggcg atattttaac gttaaatctg actacgaaga
    39421 cgttcgtcga tgcggcagaa gattatcc
//
LOCUS       DAIGQM010000020        38022 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.020, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000020 DAIGQM010000000
VERSION     DAIGQM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.020"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(428..1372)
                     /locus_tag="NOA48_001034"
     CDS             complement(428..1372)
                     /locus_tag="NOA48_001034"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0789312.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1668..2612)
                     /locus_tag="NOA48_001035"
     CDS             complement(1668..2612)
                     /locus_tag="NOA48_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789313.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2833..4047
                     /locus_tag="NOA48_001036"
     CDS             2833..4047
                     /locus_tag="NOA48_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0789314.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4069..6084
                     /locus_tag="NOA48_001037"
     CDS             4069..6084
                     /locus_tag="NOA48_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HCI0789315.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6167..7540)
                     /locus_tag="NOA48_001038"
     CDS             complement(6167..7540)
                     /locus_tag="NOA48_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0789316.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7566..7850)
                     /locus_tag="NOA48_001039"
     CDS             complement(7566..7850)
                     /locus_tag="NOA48_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0789317.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7852..9867)
                     /locus_tag="NOA48_001040"
     CDS             complement(7852..9867)
                     /locus_tag="NOA48_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0789318.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10046..10351)
                     /locus_tag="NOA48_001041"
     CDS             complement(10046..10351)
                     /locus_tag="NOA48_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCI0789319.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10440..11471)
                     /locus_tag="NOA48_001042"
     CDS             complement(10440..11471)
                     /locus_tag="NOA48_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0789320.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11678..12553
                     /locus_tag="NOA48_001043"
     CDS             11678..12553
                     /locus_tag="NOA48_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0789321.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12705..13547)
                     /locus_tag="NOA48_001044"
     CDS             complement(12705..13547)
                     /locus_tag="NOA48_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0789322.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13639..15516)
                     /locus_tag="NOA48_001045"
     CDS             complement(13639..15516)
                     /locus_tag="NOA48_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0789323.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15513..16934)
                     /locus_tag="NOA48_001046"
     CDS             complement(15513..16934)
                     /locus_tag="NOA48_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0789324.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16937..20326)
                     /locus_tag="NOA48_001047"
     CDS             complement(16937..20326)
                     /locus_tag="NOA48_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0789325.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20583..21974
                     /locus_tag="NOA48_001048"
     CDS             20583..21974
                     /locus_tag="NOA48_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789326.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22047..22694)
                     /locus_tag="NOA48_001049"
     CDS             complement(22047..22694)
                     /locus_tag="NOA48_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0789327.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22702..23388)
                     /locus_tag="NOA48_001050"
     CDS             complement(22702..23388)
                     /locus_tag="NOA48_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789328.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23394..24467)
                     /locus_tag="NOA48_001051"
     CDS             complement(23394..24467)
                     /locus_tag="NOA48_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789329.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24689..25363
                     /locus_tag="NOA48_001052"
     CDS             24689..25363
                     /locus_tag="NOA48_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0789330.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25368..26708
                     /locus_tag="NOA48_001053"
     CDS             25368..26708
                     /locus_tag="NOA48_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0789331.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26857..27843)
                     /locus_tag="NOA48_001054"
     CDS             complement(26857..27843)
                     /locus_tag="NOA48_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCI0789332.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28567..29598
                     /locus_tag="NOA48_001055"
     CDS             28567..29598
                     /locus_tag="NOA48_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0789333.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29707..31239
                     /locus_tag="NOA48_001056"
     CDS             29707..31239
                     /locus_tag="NOA48_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCI0789334.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            31378..32190
                     /locus_tag="NOA48_001057"
     CDS             31378..32190
                     /locus_tag="NOA48_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCI0789335.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            32180..32665
                     /locus_tag="NOA48_001058"
     CDS             32180..32665
                     /locus_tag="NOA48_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0789336.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32688..33233
                     /locus_tag="NOA48_001059"
     CDS             32688..33233
                     /locus_tag="NOA48_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCI0789337.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33306..34949)
                     /locus_tag="NOA48_001060"
     CDS             complement(33306..34949)
                     /locus_tag="NOA48_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0789338.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(35078..37306)
                     /locus_tag="NOA48_001061"
     CDS             complement(35078..37306)
                     /locus_tag="NOA48_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0789339.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(37339..37818)
                     /locus_tag="NOA48_001062"
     CDS             complement(37339..37818)
                     /locus_tag="NOA48_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789340.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        11095 a         7197 c         6909 g        12821 t
ORIGIN      
        1 tttaaaaaat gataaacctc tctcgaacgg ttttttatca aaaatcgtca tttttccatc
       61 aaaatctgct tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt tttttgtcgt
      121 ttaattgaat gataaaaacc agtttcttta ttcagttaat caaatatgaa cgaattagat
      181 atgaatcatt gtatttgccg ttgcggaagg attttttaat taaccacaga taaacattga
      241 taacgattcg cttattgtaa tcaacagatt aaatttcata tgttcatatg tacggataca
      301 ttttcggacc gattaatttt aaccattctg tttatttgct tacctattag atatcaataa
      361 aaaactgctt aacagctatt tcagctgtta agcagtttta ggatttttag ttcatattca
      421 ttgtttctta taatacagtg ttcaatactt ctcttaaagc acttgttgat ttgctgaaca
      481 ttgctttttc ttcttcgttg attgataatt caacaacttc acgaacacca ttttcgtcaa
      541 cgattgatgg cacacctgta aagatatctt tttcgtcgta ttcaccagtt aaataagcag
      601 atacaggcaa tacagcttgt tcgttattca agatagcttt tacgatacgt gcagtactca
      661 taccaatacc atagtaagtt gcttttttac gatcaatgat ctcataagca gcattacgga
      721 ctttatcagc aatcacatct aattcatctt gggcaatacg atggtctttt tctacaattt
      781 caaacactgg tttaccaccg acagttgtat gtgaccatgc agcaacttct gaatcaccat
      841 gttcacctaa gatatagccg tggacgctgc gtgggtcaac ttttaatttc aatgcgattt
      901 ctttacggaa acgagttgta tccaatgttg ttccagtacc gataacacgt gatgttggca
      961 gaccagattc gttccaagcg atatatgtca aaatatctac tgggtttgaa gcaacaacga
     1021 taataccgtc gaatcctgat cccatgattt cttttacgat ttggcgcatg attgacgcat
     1081 ttgttttaac taaatctaaa cgagattgac caggtttttg gttgatacca gctgtgataa
     1141 caacgatatc agcatcttta cattcttcat agccacctga ccatacagcc acattttcat
     1201 cgccccaagc cataccatct aaaaggtcca atgcttcccc ttctgctttt tcttgattca
     1261 catcgatcaa tactaattca ttagagattc cttggttgat cattgcataa gcgatacttg
     1321 ttccaacaaa acctgtaccg acgattacta ctttacgact tgtttttttc atgaataaac
     1381 agctcctttt cataactatt tgttactttc atgaaaagta tagtcttgtt tattcatttt
     1441 atcaacatgt taattataat agttgttatt ataatttttg atggaaacga attcctgaat
     1501 acgcataaca gataaatgac aaatgtttac acctatatcc cctgataata caaccaaaag
     1561 tttagaactg aaaataaatc caaaaaaatt cgctgcaacg atataataag acagcaatcg
     1621 cacctaaaac aattttcctt catatgcttt agtgaaagat tttcttctta atgtttattt
     1681 ctccattcat tgggagtaca tgttgaatac ttcttgaata atttgaataa agaagtcgtt
     1741 tgtttatatc cgatacgatt agcgatttct tccaacgaaa aactcgtttc ttgaatcagt
     1801 tccaacgcaa agtcgaattt tttctttaga accagttctt gaaaggaagc atcaaaatac
     1861 attttcaatt tattactaag atagaccgga ttgtagccaa aatgagctgc tgtttctttt
     1921 aacgtacaag aagtaaaatg cttatcgata taatctaata ctctaagcat ctcattttct
     1981 gcgcatccat ctgctgatga aaagctttgt tgttctaata aatgagtcaa ttcgatcagt
     2041 aatagtgatg tatagagatt taacgaacgg atcttatgac tgtatgtatc aaaataaatc
     2101 aacagcatat tttcaatcaa atgcgtcaaa cgacttgttt ttccgccgcg aaaatgaatg
     2161 aattgtgtat gttccccttt ttcttttgat gcatttatca aaaaagaaga aagtagatta
     2221 tttgtgcttg ccaaatgatt caatatctct gtagataagg tttcttcttt taataagatg
     2281 ttgattaaaa tatcctcttg ccctgtgtat tcgattcttt gagtagcttc tttatcaatg
     2341 atcaccacgt cactttcttc catctctatc ctttctccat taataatttg taaacatgta
     2401 ccgctataca tataattgat ttcaacaaaa tcatgtgtat gctcgggaac ttccgcatat
     2461 cgacggtgtt tactgatatg aatatttccc tgttgaaata gatcccctcg gtggattttt
     2521 ggcggtgtct gaagatggta agctaagttt aaatcattga tattcattcc ttgttcacgc
     2581 tgcagagttt cgattgattc ttcgttacgc aaaaaaaatg tctaattcag ctagttccaa
     2641 ttgactccct cctttttgta agcggtttct ttcgcttatt agttcacgct gtactgctat
     2701 tatatgcaaa gctatttttg gtttcataaa gactttctat ggttgggaca tgaacttcct
     2761 gtgattccgc tattgagaga ataaccactt catactatat ttttgataag cgcttacaaa
     2821 aatgaaagga acatgcttat gaataaaaag atgatgaaat tttctctgct gtcagtctct
     2881 cttattttga cttctgctgg tgcagtcacg tctgcaattc ccagtatgtc agctacttat
     2941 gccacgcgtt ctttatctgc tgttgaatta ttaacgactg ctccctcttt tatggtcact
     3001 atttttgttt tgattagtag ttttattgct aggaaaatcg gacaaaaaca aactgtgatc
     3061 atcggattag tgattgcatc gatttatggt atcctccccc tcttctcaca aagttacagt
     3121 attgtcttag cttcaagagc tggactaggt attggctttg gattgatcaa ttctttggca
     3181 gtcagcatga ttgctgcctt ttatcacgga gatgaacgag cctctatgat tggttttcaa
     3241 agtgcatttc aaggatttgg tgcagcttta atgacatttg ttgcaggaca gctagtacag
     3301 ttcggttggc aatatacctt tttagtctac gccatcagct tacctattct tgtcttgttt
     3361 gttttgtttg ttcctacacc tgaaacaact gaacttcaat cacatggcac agccccaaca
     3421 agacaagtaa tcaaaacgaa tcctaaaatg attagttatg gtatttttct cttgctggtc
     3481 atcgtggtat ataatgctgt atcgattaaa ttagccacag tcctgacgac ttattctcta
     3541 ggaaacgaaa ctaatgcagc gaatatctta acaatcatgc aattggcaag tatggctgcc
     3601 ggagtttgtt ttggctggct tcagacaaaa gcacatcgct atatgcttac actttcttta
     3661 ctactgatgg gaatcggctt tgtattgatt gccactgtga taaacctgta tgtgattggg
     3721 tttggtgcga tcctaacagg aatttctttt tcgttattca ttccttactt attcaaccaa
     3781 gtaagtatcc aagcgcccaa gtacgcggag agtttcaata cttcaatctt attggttggc
     3841 gctaatttag gtactttcat tgcaccatat ggtttgctct ttctctcttt tgcttctctt
     3901 gggagtaaaa cacttgctgt tttcgtcaat ggcagtatct tgctgttgat tagcgcgctt
     3961 attagccttc tagtagtaca caggacgaat agaaagacag tgataagagt agatgaagaa
     4021 ataaaagaac aattgacaac aaaataaatt tgatggaggt cgtgtaaaat gacaaatgaa
     4081 aaacataaag atagatggct ttggtatcct ggagactttg agatccgcca tggactgcta
     4141 caaaatttcc aacgggaaga acgaggtttt gactggccag cgtactggta catggatgat
     4201 tgccatcgga acgtcaagtt taagagatat tactttcttg atcaaccttc catgtttaaa
     4261 gtgacgatcc aaggagttgg gtatgtagaa attaatggac aaaaacatcc atgtggaaaa
     4321 tggctgactt gtccagctgg taaagcaaaa attcgtatct ttgtaggaca tacatcaggg
     4381 ctaccagcga tgtttatcga gggagacgaa gtaaaatcag atattggctg gacagcaagt
     4441 aattttattg aagaatatcc agctggctgg agtccgcttt atgtcgatat cgcaaaagat
     4501 ccaaatcaaa tctattatca aaaagaatgc gtccatccag tcactgaaac ggagattggc
     4561 ggaggaatct tattcgattt tgggcgagca gtgaatggct gtgtagaact aatatctctg
     4621 gatgaccata tcgaatctat cactctatgt tatggagagt ccgatgtaga agctatggat
     4681 atcgattatt gctactataa gcaaatagga atgacaagaa aaatgaaagc tcgtaaacgc
     4741 gcttttcgct atttgtttat accagaggtt tctactggaa tggttcaact tcaagttttt
     4801 catgaatttt tatctctttc gaaacaagct gctttttcaa gcgattcttc tttactgaat
     4861 cagatctggt cagtatcaga agaaaccttc aagttatgta gtgatttgtt ttttatcgac
     4921 ggtatcaaac gagatcgctg gatttggtct ggagatgcgt atcaatcatt catgatcaat
     4981 caatatcttt tttttgacga ggaaatcaat aaacgaacga tattagcatt aagaggacaa
     5041 aatgaaatca agcagcatat gaatactatc gttgactatt cgatcttgtg gttgattggt
     5101 atcgaaaacc actatatgat gacgaaagac tatgaatttt tacgcatcgt ctaccctaag
     5161 atgcaatcat taatgagata cttgatggag caaacgaatg aattagggtt tatttatggg
     5221 agagcaaaag attggatatt tattgattgg tctgaaatgg ataaagaagg aacgcttgct
     5281 gcagaacaag tcttattact gaaagcctat cattccatga tcacttgcgg agatatctta
     5341 gctgaaacat atggagagaa cgaaaattat catactcatc tctatcaaga aaaatatcaa
     5401 ctattgaaac aaaacctatt tgactacttt tgggatgaag aacttggcgc ttttatcgat
     5461 tgctatgaat ctgggagaag aaatgtgacg cgtcatgcga atattttcgc tgttttattc
     5521 gattttgcta acaaagacca acagcaatcg atcttaaaga atgtcttatt gaatgacact
     5581 atcacacaga ttactactcc atatttcaaa ttctatgaac aagatgcttt atgcaaactc
     5641 ggacagacga atatcgtcta ccaaacgatt cttgattatt ggggagggat gttatctcat
     5701 gatgcggtaa ctttctggga agaatacgac cctactcaaa caggaaatga aaagtacagt
     5761 atgtatggag atccttatgg aaaaagctta tgccatgcat ggggagcaag cccaatctat
     5821 cttttaggac gctattttat cggtttgtat ccaacaaagc caggttatga agaatttatg
     5881 atacaaccta atctagattc atttgaaaca ctgaattgta cgctacctat caaagatgga
     5941 aagatttcgc ttgaaaaaac aaaagataag atcgtgatta cttctgatag aacaggcgga
     6001 acagtgaaaa tgaatggtaa aagttatcct cttctagcaa aacagccact tgtcttaaca
     6061 agctattcaa aaataaatgc ataaaacaaa aaactgcttg cgacatatca gaagacttta
     6121 aatcttcttc tgatattgtc caagcaattt ttattttgaa gtttgcttaa ttctgttctt
     6181 tagaaacaat gtttgttctt tttccggcaa aaagaaagct agataatacg acaagtaaaa
     6241 agaaagcgat gattccaact gtcaaggcta tttgaccgta ttctcctagt ttcccaagta
     6301 caagtcctgg tactagataa tcagtatcgg caaatgtaga agaagcgatt ttaagatctc
     6361 ctaatactgg aaggataaat aatggcagcc aactaatcaa taagctattg aaagcagaac
     6421 ctaataccgc ccctcttcta ccgccagtcg agttgccgaa gacaccagaa gcagctccgc
     6481 agaagaaatg tcctactacc ccaggaatga taactgtagt ttgcaagcct atcatagcaa
     6541 acatggatag tgttcctaca aagaagctaa caaaaaagcc aattaataca gcattaggtg
     6601 catatggaaa aacgatagga acatctaatg ctggtttaga atcgggtacg agttttttag
     6661 caatcccttg gaatgctgga acgatttctg ccaacaccat tcgaacccct tgaaggacga
     6721 taacaaaccc agctgtgaat gttccagctt ggatcagtgc aaagattaca gcgttgtctc
     6781 cattgcttag ttctctttca acaaatccag gaccagctaa caaagcaagt gcgacatata
     6841 cgatcgacat caagagcatg atcgatacag tagaatctcg caaaaagctg aaacttttag
     6901 gaatctttat gtcctctgta gaacggtctt tgtttccaaa aaactttccg atccatccac
     6961 tagaagcata accgatattt ccggtatgcc ctaacgcaac ttgattgttt ccagtgatgt
     7021 tcttcataaa cggttgacaa agagcaggcg taatagttaa tagtgttcct tcgaagaccc
     7081 cgcctaataa gatcatccac aaatttgcag taaaccccgc gcttactaaa atgactgctg
     7141 ttagacaaga aacataaagc attgcttgac ctgtaagaaa aatgaattta tatcttgtga
     7201 atctagcaag taaaatattc acgatcatcc ctactagcat gatcaaagca gtaggtgtac
     7261 cgtattgttg caaagcaatc gccactactg cttcattgct aggaactact ccttgagtat
     7321 gcagagctgt ttggaacatc gaagcaaaag gggttagtga attactgatt aaaccagcac
     7381 cgccgatcag tactaggaat ccgacaaatg ttttgatagt tccttggatc acttctgaaa
     7441 atttcttctt ctgaagaacg agaccaagca gtgcaatcaa agaaacgagg atggagggct
     7501 gactgacgat tgacacaaac aaattcaaca atttatccat tgatagttcc tcccttgaat
     7561 catttttatt cttttgacaa gatcttcgtt actttttctt ttacttcttc gctgtcaatg
     7621 atcgattgca aaggtacgag cttttcatca ggtatagaag ttagcgtatc tttcaaagaa
     7681 tgctcaatga agaaataatc agccatatcg ctagatacac ttccaacatc cgtatgactt
     7741 acttcaaact cgtccacatc tgctccaaga tctgcaagtg cttgtttgat gttcatctct
     7801 accataaaac ttgttcctaa tccactttga catactgcaa aaattttcat atcattcgtc
     7861 tccttttctt atgatcgcta atatttcttc ttttgttgat gcgtgtaata aatcttgaag
     7921 attttgttta ttagaaagta gctttgttaa atttgccaaa gcccgaagat gtgcctcatt
     7981 atcgatagca gctaaacaga tgaacaaact aatgggatgg gctggattat caagcagatc
     8041 cacaggttgt tgaagtttca gcaaagacat ccctacttcg tttacgccat cttctggacg
     8101 agcatgaggt aatgcgatgt gatcgccaat atggataaac gcaccatact gctccacgcg
     8161 ctcgatcata gctttgatat aactttcttc tattttattt tctgataata gcggctgtgc
     8221 ggcaaatgtg attgcttctt gccagttttt tggttgatcc gataattgga tcatttcttc
     8281 tgttaataat tcagatagca taggacgttg atcctccttc ttttctaaaa gtttgttcat
     8341 tttacgattt aatacttgat agagcttttc ttcgtctacg ccttctttta attcgatata
     8401 aggcagtagc gccgacaaca attcttgggc agaaggcatt gaaaatcctg gtatcagcca
     8461 atctctttgt acttgattga tcagctgatt tttttccaag tcagtcatga ttggatgcag
     8521 aacatagaga gactttttct tatcagtaag tgtgagaggt acagtagaaa aaataatatc
     8581 gtaagaagtt tcgtcaacct cgtgtaagcg gtcagctgaa ttagtctctg taaaaaagat
     8641 catcgggaat aattgctgaa gttcactttt taagatcaat gaagagctaa tgccacttgg
     8701 acagacgatc acggctctta tttttctatt tctttcttct gcgtccgctt ttctgatctc
     8761 tccgccaaat agtatagtga aaaaaccaat ctcttcttca gggatgctct tccctattcg
     8821 tctttctaac ggaagtaatg cttttcttgt catttcgtag atggaagcat attgatgctt
     8881 aatttgatcg atcatcacat taggtaaata aaaagaatag gaaatacgaa aataggcagg
     8941 gaccaagtga taaaagacat tcatcaataa ttcacgaaac gaagcaaatt ctacggccat
     9001 caggaattcc atgcgatgga tgacttctga agaacattcc agcaaaaaat caagtgcagg
     9061 ctcctggaca tctccttcaa cgatcgatgc taagcaaaga gagaaaaata taatctccga
     9121 attttgatgt tcggaatagc caaggccagt caatacttgt cgactaatgt cagtgactgc
     9181 aagagaagcc aacagttcag catcttttac cagttccatg gatgtttttc caattcgaat
     9241 ggttgtcaaa ctcaaataat aagctaattc atccattcga tttggtgcga atcgaagatc
     9301 tgatagtgaa atcgttttat ctagcaaatc tctaactttg gcgtaataat caatggaaag
     9361 ggttgcggtt aaatacgtga gcccaaatct tccagcaagt gactgcatca aacgagcagt
     9421 gcgatttttt gcttctcttc ttaatattgc ttctgaccct agcagcctaa aaccagtttt
     9481 cctagtatac gacagctgac aatcttccac ttctaattca tttcttatct ttttgatatc
     9541 tgacaggact gtccctttag aaacctgaag aaaatcttga aaatgaaaaa cagaaacaga
     9601 cgttgcagtc gaataaacca tcaaataaag aagatctctt cgctcttgtt cggtatacac
     9661 agcttcaaat cgagtaatat ccaaaaattt ttctgcccag tcgattgctc ggaatttctt
     9721 tatacggata cgggtatcat ccacatattc ggcaaaagga gttaattgtt tgatcgcctc
     9781 gcttgtattt acttcgatga tctctgctgc tttttctaga ctgatttctc ttggtgtttt
     9841 caggagataa ctaattttgt agttcacagc gctgttcacc tcctacttat attctagtat
     9901 ggtagcgctt ttaaatcgag gggtgtttgg tacaacttac agttggattt tttttacgac
     9961 tgtaccgaac gatttctatc gaatggatac agaaaaaaag caggtgacca aatgtctcct
    10021 gcttttatga attgatttcg tccgatcaat gatgatcatg tttatttttt gaggtcagtt
    10081 cttcaaattt ttctttgaca tcttcaaccg ctttttcgat atctttttca aagtgattgg
    10141 gctcattagg ctttgtttcc tcttctacag aatttgaacc agataaagct gtttctttat
    10201 tttctgtttc accagagttt gtgccagcta atgattcttc tttgtcttct gtttcaccag
    10261 aattagttcc tgctaaagcc acttcttctt ctgttttagg ggccattgaa cctcttaatc
    10321 gtttgtgttt ttcaccgtca taatttgtca tgttggttcc tcctagtagt tctatacttt
    10381 ttcatcgtac aataagacag tttatgcgtc aaaaaacaaa cccgattctt acaaatatgt
    10441 catatttttc cttctgattc ttgaatgctt ttgattcctt cttccaaaat tttcatttgt
    10501 aagattgttt cttcatcttt gatgactttt tctgcgccat taactaatgt ctcgtaaatc
    10561 ccttcgtaga cacggctgta atcaccaacc tcggaaatta ctttttcttc atgataactc
    10621 ccttgttcat ctatataggt caatacacca taatgttcgg gcaaatcgat accaaagtct
    10681 tcatgatcag gcatgtaaaa cattttcaga tgttcttctt gtcgatcttt tgtttgtttc
    10741 acgaacatcc ctttttttcc gtaaacgacg aaacttggac gttctttgat gcggaaataa
    10801 ctggatttta tcgaaatttt catatttcca tagaaaaaat ccagatcgaa gtaatcattc
    10861 attcgtcctt tccctaaaag ttgacgtaca tcatagctga tatcatctgg ttcgccgaaa
    10921 taagaaagaa cttgatctac tgtatgacaa gcatgtccat ataaatagct gttcgcagta
    10981 gaaaattcat gcgtattttc tggtacttcc ggtctgaaat aatcataatg catttctact
    11041 tctaaaatat cccctaattt tccgctttcg attacttttt ggactgtcaa gaagtcagaa
    11101 tcgaaccgtc tgttttggta acattggata aatagacctt tttcttttgc taatgcaaat
    11161 aactcttctg cttcctttga cgtttctgca aaaggtttct ctactagtac attcttacca
    11221 tgttcgagtg ccatttttcc atattcataa tgaaattgac taggtgtagt gatgacaact
    11281 aattggatct caggatcatc ccaaagatca gacagctgat cagtatattc gatgtcttcg
    11341 aatgttttcc acactggttc agatggggaa aaaatttttt tgatattgat tttgttcgta
    11401 agttttcttg aaaaaggcaa atgatagcga tttgtactct ttccattgcc aagataagcg
    11461 attgtaagca tgagtggtgc ctccttttat tgatgttttc agtatatcct agaaaagcgc
    11521 agaaagtatt tataatagct attctggtaa aaaagttcag aaaaacactt gttatcattc
    11581 ggtttggtga aattaatgtt caaagtaagg ataaaaatca aaaagatagt agcggaacca
    11641 agtgtttatc agtaagatag aatttggagg tcagatcatg cttattgaag aaaaactaac
    11701 aaaacaagag ttgtttacca cgacagagaa acggattgtc gattacatcc gtaggaatat
    11761 cgaagctgca gtctacatga cgattgaaga attagcaaaa gctacgtata cttcccattc
    11821 agctatcatt cgtttatgca aaaaaatggg attcagcgga tttaaagaat tccgtttcga
    11881 gctggggcgg gaagttcatc aattgattgc tcagttcaat caaacgattg atcctaattt
    11941 tcctttttca agtgaagata gcactcagca aattgcaaag aaaatggcgg atttatcgat
    12001 ccagtcaata aaaaaagcac aattgcagat tgaacatgaa gatttagatc aaatcggtaa
    12061 agtattgaac aaggcacagc gaatctttct ttttgcaaaa ggtgattctc aaatcacggc
    12121 aaggaaattc cagaataaaa tggtcaagtt gaataagttt ttgatcatgg ctgaagaata
    12181 cagtgattct tcttggaatg cagccaattt gactagcgag gattgcgcca tttttattag
    12241 ctacagcggt cgcatccatc attatgaacg aataatgacc tatttgaagc atgtagaggc
    12301 ccctaccttg ctgattaccg gaaatcagca ttcagaaatg gccaaacagg ctgatatgtg
    12361 tcttgttata tcgcaggagg aatatgattt tgctaaagta gcgactttct cctctcaaat
    12421 tgccttcgat tacgtattaa atacgttatt ctcagtgata tattctcaaa attttgaaga
    12481 gaatatccgc aacttgaaaa acaaacaaga attgatgcaa aaaggccttc ttaaagaata
    12541 tcggaaaact taagaaaaga tcctcattta gtaataagaa agatagtgtt tgataggctc
    12601 tctttgatat catcataaaa acaggctgaa gttttctttt tcaaacctca gcctgtttgt
    12661 ttacggaacg attcgaatag atatattata gaaatgagga atagctaact tctgtttctt
    12721 attttgaacg attgacgaaa aagatatata agaaggagga aaatcagtat acatgcagct
    12781 aacaatccat acaggaaaaa tcgtttgttc tcggatactt tctgtacttc tttttgaact
    12841 tcttttgcat gataaggaac ccggtgccct ctgacaagta agcgatgact gttgaccata
    12901 taaggtgtac aagttaggag tgtcacgaaa tcctgccctt tttcgattct cagatctttt
    12961 gtatcagtcg gttctaccgt cttgatctga tcgacttgat aagcgagtgt ccgtccattg
    13021 atttcgatat agaaagaatc acctaaagtc agtttcggta agtctgtgaa caactttgct
    13081 tgaggcagtc ctcgatggct ggaaataacg gcatgtgtat tttctccccc cgtaggataa
    13141 gacgttcctt ccaataatga ggcacctttt tctagcagca cagtattcgt ttcatcaaaa
    13201 attggcaaat ggacattgat ctcagggatc gtcaaaatac cgatcgtatg tttctcaaaa
    13261 taggttctat cctttttcgc aggttctttt ttcttagtaa agggatctgc acctggattt
    13321 ccaccttctt ttgctaattg ctggtttttc tttgtcatgt tttcttggat tttagccatg
    13381 acttcttcat tttctttgac cgcttgttgc tgataatgag agatgatctg ctgatccaga
    13441 taattattca gcgcgtcgct aacaaatgga taagctagta tccctattcc tgagagaagc
    13501 aagaaaagca tcagcagatc tagaagtttc cttttctttg gtttcatttg tgttctcctt
    13561 gtgatgactg tttgataata aaagaaaaag gagcatttgc gtaatccgct gctccttttt
    13621 ccaattcttg caaaaagact aaatctgact gtgcttgcgt ctagcaaagt acagtccagc
    13681 aatcagtaga aggactactc ctgcaccgat atacacatag attcccttac cgcctgttga
    13741 aggaagtgta cctttgtgtt tatttggtat tttttcagga gaaatcaact gtcctgctgt
    13801 tacataagat tgttcatcga tagtaaatgc tacacggttt gttaatggaa catatttttc
    13861 tggcgctttc gtttcttcca gatagtacgt gccatatttt agacctgtca catcgattaa
    13921 accgttactt gtggttgtaa aaaccgttgc tgattctttc gccgataccc agctgacggc
    13981 ttttgtggat gggtcgatcg ataaatattt cgctgtgtca ctatcttgat cacgaacgac
    14041 gaattctgct ccagcaagtg tttggtctga tgtaacgtca ccatctactt taacaaatcg
    14101 tttgccccca gtaacgacat cgactgacgg tggtgtttga tcatttgtat gcccgttatc
    14161 gacatttgct tggttagaaa atcctttggt tggatctgct ttttcgttca aatgcatata
    14221 gtaaacgaat ttcaatgtac cgccaggagt taatgaagga atataattcg gatcaactga
    14281 aaccgtgaat ccgtctgttt gctcagtgac agaataattt actgggtcga tttctttatt
    14341 tccatcatat aaggcataag catacgttcc tgaagaatca ttatcaaatg ttaaagcagc
    14401 gtcatgagta tcgataagtt tgaatgttgt gtacttgttt tgcgttcctt ctttatcagc
    14461 gatacctaat gggatattga cagaaatctc atattgaatt ttttcaccga ttgcgacatc
    14521 ttttccattc aattgaggtg ttgttttatc aactttagac gtatcatttt tgatggtctt
    14581 ttctactggt gtttggctat ttgccaggat ctcaaaaggc gtgattgttt gcttttcaat
    14641 catttccgca ttatcaggag cttttacttc ttctaaatta tattttccaa cttctaaatg
    14701 attaacgatc aactggcctt tttcaataga tgcctcggca aagtcattgt tgccgatgtc
    14761 ataagaatga ccagtaatga aatgtttggc tttggtttga tcagttgtcc aagtgtacaa
    14821 tccatctgtg acactttgga tgtatttttt gacgcttggt gttccttctt ctttagaaat
    14881 aataaattct gctccattta gtgcttcgtt ttcggcagta ccgatttttg taactttcaa
    14941 cgttccatca ttacagactg tatttttagg gtagagatgg atagtatcta gttcttctgt
    15001 cccgtattta taagagccat ctgcttgttt gatcatctca tatacaggga aagctaaaac
    15061 catgtttgcg gcagctgaca ctccgtcttt tggttcttct ttgatcgtgt agactgcatc
    15121 tttcccattt tgttttttag gtaaagataa agtgacattt ccatcagcat ctgtcgttcc
    15181 tgaagcaact ggtgtaccag gagtcaaaga ctggactgct tgttttgctg catccacgga
    15241 cgctccttta tctcgttgcg cataaaattc ttgagtgacg ttataaactg aaaatgaaat
    15301 atcggctaat ccttggtatt gatcgaattc gctcatttct ttcccgctgt tttggattaa
    15361 aggatcgggt aaatcagtca ttttcttttt atgaaggatg acttgagctg ctgtctcctc
    15421 tgcaaacact ttttttgcgc cgaagctgtt tgtgagtaat ggtaaaataa ggaaaaggac
    15481 tcctaacata acgtttattt ttttatgatt tttcattttt tcactcctgt tctttttttg
    15541 ataaacaacc agattgcaaa gcttgcgaat accataccaa caacgcctaa aagtgtattt
    15601 ttcgtttcgt ttgtttttgg aagaaatgga cggctatttt cttttttatt gactactttc
    15661 aatatactgt ccgcctcttt atcctcagaa agaaaagttg aaatggtaaa cggaatttct
    15721 gtttcactta aaatataacc agaaggtgct tcgatctctt ttaatcgata acttcctgtt
    15781 ttcaacccgg aaattgaaaa agcgccattt ttatcggaaa tcaggtgaag cgcatctgat
    15841 tcgttctttg tccacttgta tccgttggct gtttgctgga ggtaatttcc tgctttgttt
    15901 ttaataagga atactgcgcc agctaatcgt ttatctggtt tatttgtctc gattttgaca
    15961 aattgcttac tccctgtata tacagagact ttctttgtac tgacaccaaa accaaaatcc
    16021 agtgttccgt tgttgttgat ttccttgttc gcctgtgctg tactgcttag ctgcatctga
    16081 taagaaatgg tcagtttttt tccagcatat ttttccaacg aagggatcga aaataaaaca
    16141 tcaaatccgt gaggtttctt gtgtatgaca aagccttctg tcagcttttc tccattcgat
    16201 gaaatcgtta aactattagg taaaaacgtt aatgcttcat ccgcactatc tgacaattcg
    16261 aacttttgat agtcaaggat atttacagga attgtcgtat gcaaggaata agtgattttt
    16321 tcaccaatcg taaaatcatt tctaggctct tctaatacct tctcaaaagg tggatcaggg
    16381 tagtcgtttt cttcattttt aggatacaaa tggatagttg aaagtttttg attgttttgt
    16441 ccatgtacag gaagaacaac taccatattc tctgcctttt ctttgacgac ttctggtact
    16501 ttggattcaa tgaaaagata cgctttatct cttttttctt gatctttagc ggccagagaa
    16561 aaagaagcga taccatcttc gttgttaaga gttgtagttg ttgcttctgc ggtaaacata
    16621 ccggaagacg caccgttttt tgcgatctct gcttgtgctt cttctaccgt tttgcccttt
    16681 tcccgtagat ggtaaaaaga atctgtgaca tcataaactt ggaatgtgac accatttaat
    16741 cctcgatacg tttgtaataa agctttttct tgtccgtcat ttggatgatt tttcggcagt
    16801 tgcccgtttg ggaaaagcaa tttgtgtaaa gtaatctgaa ccatttctgt ttctgtttct
    16861 gttgctacct gagtaaaagc tggtttaaat agtaacaaga agagacacat actaagccaa
    16921 ccaagttttt tcatatttag ctgccccctc tttctttttt caaaaaaaga taccaaatag
    16981 aaaacgcaca accaatcatc cctactagat agattcctaa acggccaatt cctcccgttt
    17041 caggtaatgg tacttttgcc tgattcgtga tgtctaaaga aatctggttg tttttggctc
    17101 ctggtgacag aacagattca tgatcttgtc catccacttg aattgaccca tcttcgtgta
    17161 taactatagt aactggctct tttagacctt ggtatccttc tggtgtaaaa gtttcggtca
    17221 gcgtataagt tccaggtttt aaattttcga atagaaaggt atctgtttct tgtccatctt
    17281 ttggcgattc taagtccatt tctggtccct gcagtctgaa ttttgctcct tttaatgtct
    17341 gtccgttgtc ttcttttttg tgtaccgtta gatcaaacgc ttttagtcga ttttgatgag
    17401 tgagcgtcca tacattattt gtcatctcgg tattttttcc cgtgtaaatg atttttccat
    17461 atttatcgat ttggaattca taatttcccg gcgaagtatc atatccggca ggaccagctg
    17521 tttcaacgac tcgatattta ccaggtgtga gtgaatcaaa actggcaaga cctttttcat
    17581 tcgttgtttg gctgtcaatt ggctgataag taccatttgc ttcttttttc tgtagggaaa
    17641 atgctgctcc tttaagattt atctctttgt ccgtcccttg catcgcatac ttacgtactg
    17701 ctacaggaac ttcaacaaaa ggattttcaa tagtcaactg gatcgtatca tcggaagtag
    17761 tgactgtttt tccatcaatg gttaccgtac catcagaagc gatcttgatt tcccaagtag
    17821 tctttttgct taatccatgc ccttctggag cttttgtttc tgtcagcgta taggtcattt
    17881 ctttttgcaa tttgacattt tctggaagag aataggttcc gtcgccatga tctgttagta
    17941 aagtatcaat agaatctcct gttaatttga aaacagcgcc aataagatcc ttttcacctg
    18001 tagaggaatt tttcgttatt ttcaagttta acggtgtgaa ttgtttagta tttttccatg
    18061 tcattgcatc tatttgttga gaatcgtatc ctggtacagg taattctttg attgtttggt
    18121 aactgaatgc ttgaccttga ttattgtatt gaggtagtga taatatctct tgataacttt
    18181 ctccgctatt tgcagataat ttgtcaatgt ctgcacgttc ccacgtattt gttgtatctt
    18241 tagctggttt aatgattcga atatatccgt ttttccaagc tgcagcattt gtcgtatgtt
    18301 cccgttgaat ctcaaaagta acttgatctg gacgatcagc tagattgttg tcaaattctt
    18361 cccataactt tttgatgtga agactgactc cgggagcttt agcagatggt ataccgaatt
    18421 cagctaattc attggtatca atgtttggct ggaaagttgt cctgccgttc atttgatacc
    18481 agaaatttgg atggaagtcc tcattttctg tttggattct cacttggtaa tggatttgga
    18541 tttcttggtc ttttcctaaa tagatctgat tgctcttgat ggtatttcct tctatggaaa
    18601 tagatggagt gaccgttgta ggacttgtcc ccacactctt gactgaaagt gtaccaggct
    18661 gataaatgaa tggttctgcg attggatcat ttatttgtcc attgcttaca gttgctgaga
    18721 tctgtacagc ttttttggct aggtattcag agatatctgt tgcatgatca gctgattcat
    18781 agtaaagatc gcctttttca tctgatgaaa ccatttgtcg catacgagac tctacttctg
    18841 cttttgagag accagctgcc ggatcgcttt gaagttggat gccaagacca tgtatttcga
    18901 ttcctcgttc tttgagtgcc atcgcttctc cgatggttgc gataaacgta ctgtcgattc
    18961 ttctggatag attgttttgg tcaggtgcat catagattct tgagattaga gaagtatttc
    19021 ccggccgatc ttgcgtatta gaaaactgag ttccgtaata attgctgctt gattgtgcgt
    19081 gtacccgctg tactttatag gaaaatgttg gtacaccatc cgtcagcaaa acgatcactt
    19141 ttttatgtcc atttggaacg gatagcatgc ttcctgcatc tcttagtgct ttttgtgtaa
    19201 aagtaccacc atttgtccgt gaaggtgtaa tggattttac ttgatttttc actgaatcaa
    19261 atgaacccat ctgtactgca ccgttactgt agctatatcc ttcgcttgag tagccgacat
    19321 atcccatatt gattttgtct gtgataccgc tatctgctaa agtatcgaca aaacgatcga
    19381 caccaatctt tacttcaccg atccgattat tgtcgttcat acttcctgac cagtctacga
    19441 ccaatacgag atcaagaggc gtgatatctt tttgtacatt tccacgagca ttcaaataaa
    19501 catcaaacaa tccgggtgta cttgtttcct ttgcatactt tcgtatcgca tagtctgctt
    19561 gattaccggt tcctccatat tcgatatacg aatgggtccg atcattagga tctccattcc
    19621 aagaatttat accatcccat tgatttgttc cgtttttatt gccttgatga tcaagaacat
    19681 ttgtatttcc tgtaggttgc caactggctt taggataagt gccctgatca tctgttgtat
    19741 attctgtagg aatcgtttga ttagatggca cactcacagc tggcaaggat aatgtaggca
    19801 atgtaaatgg gctgacagaa ttttcgtttt cttttgatga ttcttcttct atttcgtctg
    19861 gctttggtac tgacacatct gtatctttct tattttctgt ctcatcaata atgtcatatt
    19921 ctttattatc gacgatcagc ttgtttgcct ggctgtggta aagtgctgga tcgattggaa
    19981 aactcagatc gatagtttgt ttagtgtttg atgagatttc caacgtaatt ttcccgctat
    20041 ttacctgata agcatagcca tctccttctt ttctttccac atcacttaag taattttcga
    20101 ctagaccaat ttctttttct atcttttcag cactggtgtt attcgcattt agcttgatgt
    20161 tcagtgcttt ttttccagac tgatccgaaa tgacttcagc tgaaattgtt tctaaaactg
    20221 ttggatcatc tgtagtgtct gctattgcag ataatggcac aaagtttgat aaactcaata
    20281 ttatcagcat gaaaataact ttcagtttct tccctgtggt cgtcattttt cccctccttt
    20341 ttcttttttt ctgttttgac gtgaatagtg aaaattatta aaataaacag gcgttacata
    20401 attttattta ttttaatatg ataattatta tacgaagggc gctaaaggga atcacaccaa
    20461 ttttcatacc aattggtttc atttatgaag ttgattcctt cgattaatga gcgtttcatt
    20521 gaaagaaaag ggttgaggga gaaaaacata tgatcaggtt gttggaatga aactatagaa
    20581 agatggaaaa aatcattcga attctgtcca tttctgacaa gtggatgact aaaaaagaac
    20641 ttgccaaacg aattggtagt tcagaatcta catttgtaag gtatatcgaa gagatcaaaa
    20701 tccgctgggg aacggatgta acgattcaat cttcacaaaa attggggtat cgtcttgaac
    20761 atttgaatgt accagcttat ttaaatgttc tgatggaaat gtcgcaaagt tctacaaaca
    20821 gtcgtttatt aaatgagatt attgtcaatc cgggtaaaac gattgagtat tattgtgaaa
    20881 aaatttccat cagccggtct tcttttacac gtaagttgaa acaatgcaat caaattttag
    20941 aaagctattt attaaaagtg atcgttgacc aaggttttca gttaactagc cttaaaagtg
    21001 agctccagtt gcgtatcttt gttacctttt tctttttaag ttactacgga agacgcacgt
    21061 tgccatttcc aatcgaaaaa aagaagatca aagaaattat ggtcaagaat aattgtcaga
    21121 tgaatttgtt tcaggaagaa agcccatatg agcaatcttt ctttattatg tattttgttg
    21181 tgcatctcat gagagaatcc caaggaactc catttgaatg gaaagctgga gactcttatg
    21241 tacagttgat aaatatcgat aaaaaagact tcttaatctt gaaaaatctc ttaggaaaat
    21301 tgaagtacag cagctatata aaagtagtga actattttgt caatacgatt ttttcagaat
    21361 tttcggagaa agaaaaaaat gaaatcagtg agcagatacg aaaaaatatg tcctactgtt
    21421 cgttttcatc cgctgattgc aaagaaaaaa acgaagaata tgttgttcaa ttattaacgc
    21481 aaatttattt tttctcccgt attttcccat acgatacgac tcatttgacg atccgtgcaa
    21541 cttactttgc acagcagatg caacaccgcc agatacgtct atatgctgga tttcgtgcag
    21601 aacttcaatt ttattccact ctactgaatc agaatctgat ttattattta tctagctata
    21661 tcttttggat gcttatcggt aatcctgaaa ttcaccatta tacttctgat aaaaaaatac
    21721 tgattatcag cgacttaagt cttcgacata gtcaatatat tgaagaatat atcagtgata
    21781 ttcttgctgt gcataaaatt cactctgaga caactgctat tactgaagat cagctgtcga
    21841 aatacaatct tctcgagtat gatctgatcg ttacgaatca acccattttg aatgcccatg
    21901 ttcctcatat attgattgat gatagtgtgt cattcgcaaa tgaagaagaa ctcatccgct
    21961 tattcgagtt atgaataatc aaaaaacagc tatgtataaa ccaccctgat aaaaatttca
    22021 ggacaaatac acatagctgt ttctttttat tgtattcctt cagcaatcca acgagattta
    22081 tagcgaaagt cttttaacaa ctcttctttt gtccaattat ttgcaatgag atccgtcaaa
    22141 gtgttcatta cgagggtcat ggaaaagtat aggaaactaa ctgcttcttc cgacgattga
    22201 atggagaaat gattgattct taataattcc agccattttt cgttcattgg agaatcagcc
    22261 gatagttctc tacgtttggt tgtctgctga tcatttcgct gggttaacaa gtataacctt
    22321 tgccaataga tactttcgtg atctaagtcg cagcaccact ctaaatattt ttcgatcccc
    22381 aaaaagaaat gttgtttgtt ttcgctaatg aattttaaga tatcttgatg gactatgtga
    22441 gaactgcttt tgatcgtata caaataagca tcttccaaat cttgaaaata tttataaaaa
    22501 gcaccgcgcg acatccccat cttgtcaacg atttctgaga ctttgacttg gctgatgtgc
    22561 tgtgagcaaa atatctccag taataggtca tcgattctct gtttctttgc gttcgataaa
    22621 ttgaaaaaag tttcttttgg catccacatc tctcctttat ctctgattat acgtggatag
    22681 cccttcattg tcatgaagga ttcattcctt ctttttctct tcttctgtca agtacccatc
    22741 ttccattcga taaacgcgat cactccattg aatcatacgg acatcatgag taaccataat
    22801 agtcgctttt tgtttctcat gagcttcttt aactagtaat ttgacgactt catatgcatg
    22861 atctgtatcc aaactagctg ttggttcgtc tgctaagatc aagcttggct cattatataa
    22921 agcgcgagca attgccactc tctgtctttc tccaccagaa aggtctttag gataactatt
    22981 tttaagtgac tggatatcta aagattgcag caaggaatcg atttttgttg aatcttcttt
    23041 ttttgaagta acttggtcaa ctagttcaaa ttgttccttt accgttaaaa aaggaatcaa
    23101 attagagctt tggagaataa atcctatttc tttaaagcgt aaatctgctc gttttttttc
    23161 tggaagctca gttagtgagt gaccgttgat cactatttct ccggaagtcg gtgtttgcaa
    23221 tcctcctgaa atggtaagga aagtactttt acctgaacca gaaggaccaa tgatgctgac
    23281 gaattctcct tcctttacat aaaaatcaat tgctttcaaa gctgagacct ttgtatgacc
    23341 agaaccaaat gttttggtaa cttttttcat cgttaatatt tttttcattt ttattaacct
    23401 cctattgctg taattgggtc tactttggtt atcgtacgta tcgaaaacaa tccgcctagc
    23461 attgcgacaa tgatcaaaat cccactatat agcaaccatt gtgaccaaaa aacagcaaaa
    23521 ggcatcgcgc ttggtaaaat cagactagtc aaataagcaa acaaaagagc aagcagaacg
    23581 cctaccaccc caacaataaa ggactgtgct actaaagatt tagcgatgaa gaaatttttg
    23641 atcccttgtg ctttcattac tccaaaaata gcagtcttct gaagtgtcat cacgtacatg
    23701 aaaataccga ccacggcagc aaccactaag aacaaaaagt atatcatcgc atttaaggtc
    23761 atattttggg cagaatagcc aggaatactt tcaatgaatg tcccaatagt taataactgt
    23821 agacccttcg atgctttttc tttcgaaatt ttagctgaat cctttattac gatcccattg
    23881 atcggctgtt cttcttcaga agcaaacggc tgttgtccat acttcaaagc agtccacgta
    23941 tctagggacg catagatgac gggagaaact gtgtaataag tttcaggaaa gataccgaca
    24001 atcgtcaaag gatcgtcgta actgccaatt ttgatcgtat ctccaatttt atagcctgaa
    24061 tcagccagat tttgagagat gatgatttca ttctttgttt taaattcatg ccctttcgtg
    24121 agttttggta ataaaaatgc ttctttcgtt gtgccgaaaa ctgtaacatt ttctttgttt
    24181 tttcctttga ttgctccgct gtacaatccg attggtgctt tctctcctcc ttcaatgtat
    24241 ttcagatctc ctcttgttaa ttgtgaagct gcaaatactt gatttgcatc ctccgacaaa
    24301 acaatctctt gtgcgtccca atcatcgatt gcttttttaa actcttctga aagtccattc
    24361 gctagtcctg acaacatgaa tacgacatac gcaatcaaga acataatacc gacgatcaag
    24421 ccatatcgta atttagaata gcgaatttct ttgatagcta gaaacatttg tttttcctcc
    24481 ctatgataga ttgatagtga caaaatgtca cttgttgaat agtgtaactc taaagtgaca
    24541 atttgtcact tgtgttgttt ttttcttatc aataaattgt ctaagacatc tttcgataaa
    24601 accttaacat gagtcataaa aaatttattt aagccttatt tatgctttcc atgataaact
    24661 aaagtgacca aatcaatgag gtgggaaaat gattaaacta ttagtagtag aagacgataa
    24721 agtattatcc aataatataa aagaaatact cgctgcaatc ggcgagataa cacaagttta
    24781 tgatggtagt gaaggactgt tcgagttgga aagtggagtt tatgatcttg caatcttgga
    24841 tttgatgatg ccggaaatga atggatatga agtgttagca aaaatacgga aagaaaaaat
    24901 acagactcca gtattgattt tgactgcaaa agatagtttg gaagataaga ttgaaggatt
    24961 tgaacgaggt gcagatgatt atctaacaaa acctttctat cgagaagaac tgatcatgcg
    25021 cgtgaaagca ttattgaaac gctcgctagg tctctttgat gaaaatgttc tgaagtataa
    25081 ggatatcagt tgtgatttaa aaagcaatga agtcttgtat aaagaacaag ttttgcccat
    25141 acaaggaaaa gagtttgaat tgctcgttta ttttttacaa aataagggaa tcattttgac
    25201 aaaagagcag atatttgacc ggatctgggg atttgattct gatacgacga ttacagttat
    25261 tgaagtttat atgagcaact tacgaaaaca tctgcgaagt actggattgg ataaagaaat
    25321 caaaacctta cgtaatgtcg gttatatact gcaaagggtg tgatgcaatg aatggagata
    25381 ttacacgaaa gcaacgtagt cgcttttttg cgacaaatgt agcagcattt gcttttatct
    25441 tttttctttt gggattcatt actttacaga tattaaacca atctgcatac agagaaacag
    25501 atctgtcatt agagaaaata aattttgatt ctcgaacagt acaattagag atacaaagat
    25561 atcagcaagg cgatcccttt ttaaacccga ctcaaacgga acaaaacaga acaaacatgg
    25621 aacagccatt aatggaacca tcaaatgacc gttttaacac tcaagtgatc ttgtggtcta
    25681 aaaatggtga gatattgaat aaagcagcta ttggtgggcg tttcaaccaa atcaaagaat
    25741 taaaaatgga tacgaaaaat ctgaatacca tccaaaatat tgaattaaat gaagacagtg
    25801 gctcatctgc cctctctttc cgttcgatta cgaaaaaagc ggagacgaat caagatggcg
    25861 ttgcctacat ccaaatttta gaaaatacaa atcaaatcaa gaattcatta gcgacttttc
    25921 gcacgattat gattttgtgt atgattgttt tttggattct ctctattggt atcagttatt
    25981 acttgtctag tctaagcatg cgccctatta ttctttcttg gagaagacaa aaagaatttg
    26041 ttgagaatgc ttctcatgaa ttgcgcacac cgttaacgat tattcaaaat agtttggaac
    26101 atctttttac caagcctaat catactatta ttgaagaatc cgaaagcatc gctcaagcat
    26161 tgtcagagac gaggcgcctc actggattga cttcggattt gctgacaatc gctcggaatg
    26221 attctgatca gcagctgctt tcaaagcaaa tgatcaatac acaagaatat atcgaacaac
    26281 ttgttaaacc atttcaagag atggccatca tagatggaaa agagtttatt ctccataacg
    26341 atgcaacatt agaagtacca attgatgaaa aaaaaatcca tcaagttttg gttattttgc
    26401 tggataatgc attaaaatat acgaatccag aagataagat cattttggat tcatctgtta
    26461 accataaaga atggctgatt cacgtaaaga atactggccc ttctatcagt gaagaagatc
    26521 aagcaaggat ttttgatcga ttttatcggg aagatcaatc tcgggcgaaa gagactggcg
    26581 gatacgggct tggcttggca attgcaaaac aggtaatcga acagcatcat ggacagattt
    26641 ctgtatccaa ttatcttcca caaggagtcg attttaaagt ccaattgccg ttgaagccta
    26701 aaaaataatg cttatcccta aaaaagggct gtgacaaaaa tcttgtcaca gccctttttt
    26761 gttgcgaata aacggtgttc cagaagtagc ttcttcggaa ataagccgaa atttctttaa
    26821 gctgaccact tctgtcacaa cctctttagc ttacgcttac gattttttat tgcggtcttc
    26881 aatgtgtaca tcaccgcttg tgtcaatatc caattcttct cggctaacat cttctgtcac
    26941 tttttcaaca tcttcatgtt cttctttatg aatcccaact tcttcacgaa taactgtatg
    27001 tttgcttaca tctacttgct cttctttgat tgggatagta atcgtgtcat cttccaattt
    27061 ttcgtctgtt ccctgtgaag attgatctgt tactggtttg cgttcgatga cgatttcttc
    27121 acgtttgacc ggtacttcta ccgtttcagt atcgttgacc acatgtttgt ggatgtcgac
    27181 ttctccagtt gtcacatcat gtgtatttac atctaatttt tcttctttta gttgaattgt
    27241 atcatcatct agatttggtt tgcgatcgat gtcttcagtc ttgcttgtac ccattgtatc
    27301 agtctcgcca ggtacgtcca tcggatcagt tcctggtgtc atattcaatg gatccgttgt
    27361 attttgaaag cctgtcgtgc cacctacgtc cattggatct gttccagtgc cagtttctaa
    27421 tccagtcccc attgtgcttg ctgggctaac agtatcttgt gtatccattg tatcttctgt
    27481 tgtttctggc tgacgatagc cttttactgt gatgacaaat tttccatcag aaatatctcc
    27541 tctatattga tataaaggat cattttctgg tgtagccgtc tcagaatcat aggtatcaaa
    27601 agaaaaagta tcttttattt tttcccataa agaacggtct tcttcaccat ccatccgatt
    27661 ttcatctgtt tcaacatcta taccagacaa tccgtcaaat cctagtctag atgctgcttc
    27721 atcagtagta taaataacga tatcatctcg ttcataccct tcgttacgca accgttcaat
    27781 tactgataat gcttcttccc tcgtactata gcttccgatg accgttaaat ttttctcttc
    27841 catgtaaatt cctcctagca aatagattta tgattggtat attgttactt ataaatttat
    27901 tctataggag acgattgttt tctacaaata tttagattgg aatttgatta aaacaattta
    27961 attgaaattt gaaaacattt atgttaatga aagtcatatt ctaataaaat gtcatttgtt
    28021 tctatatgaa tttttatgaa aaatttcata taatttccac tcgttgtgat ggtttaattt
    28081 atccaatcca tcaataagca aacaacttat ataaaaaagg attaattctc aatataattg
    28141 ctcctaccat agaataaatc ttcatgtaaa gtaatgaagt accaactatt tctaatactt
    28201 ctttaagaat tatcccaaca atatcgttag acaaaccatt attgaataaa tggagagcca
    28261 atcgattctg aaaaaatgtt ttctaatttt tcggaaataa aagaaagagc ctcctgccat
    28321 tagaacgaac caaatccatt tcattgctca tgaagtaacc acatagctaa aaagaggata
    28381 aatcaattaa aagatcaaaa gaatgactgc actaataaaa taactaaaaa tgtatcttct
    28441 tacttcatat cttttagcta gtacttagtt aaaaatttgc ttcctaagat caagacaaac
    28501 tgtctatctt catttgatga aatgcggtaa aatatagaaa atgaacacta ttggagggaa
    28561 tttgtaatgg acagcaaaac tagaaaacaa ctgcaagaaa agttaaagca acgtacacac
    28621 ttgctccctt ccgtctttca acagttttta gaagaaaatc gttcttccct ttcattaggc
    28681 agtcgctatg aatacgcaaa agattttcat ctgtttactg attatttgag aaaagtattt
    28741 tctgaagaag tggatgatca gctgattatc catttagaaa aacaagatta tcagaatttc
    28801 ttagctaaaa tctatcgaca tactcgttcg ttccaaacta cagcgaacca agaaacggag
    28861 caattgtttg aaaatagcta ttacgggatt tcaaggaagc aatattcatt aaatcatttt
    28921 ttacgatttt tgtatcaaaa aggactgatt gaagaagaga tttctctttt gggtacaagt
    28981 ttaccggaaa caaccaaagc agctccgcga tatatcgatg cagaactttt caaagatttt
    29041 gagcatttgt ttatcccgat tgaaggcttt caaacaagca gagaagctag ctttgaagaa
    29101 aagaatagac cgaggaacct tgcaattact gccattcttc tgtattgcgg attaaagatc
    29161 catgaagtag tagaacttaa acgtaaagat gtatctttga ccaagcagat tcttaatctg
    29221 aatagaaaag aaaacagact gaataaagta ccaataccaa aagaagcgat gccatttctg
    29281 gagaactatt ttaagttaac agcacaaaat acggacgaaa attcttttgt ttttcgttcc
    29341 tcacatgatc agcaaatttc tcctcggact attcgccaaa ttttgagcaa aattacagta
    29401 tataaaaacg tatcgccaga actatgcaga aaaacatatc gttattatgc agaactatat
    29461 ttagatgatg ctgacgcggt aaattattta tgtggtaatc gatacctctc atcccattct
    29521 tttcaagata tctgggaaaa gatggttgat ttttcttatc acgaattagc ggcattcgtt
    29581 cgggtttctt ccatataaaa caaatgtatg atcttttttt cacaataaac tatgttatta
    29641 tataaaggat tatgttacga ttatcttgaa tttgtatatt acttaacaaa agataatgga
    29701 gtgtgaatga tggagaccat aacgtattcc cctttgaact tatttacgaa ttttcaagaa
    29761 gctgcagcta acttttccga gaccccgatt atctttgatg agccactttc agctttccca
    29821 gaattaggac ttgaaacaac ttacaaaaaa tgctgcgaaa gtgtgttgaa acgggcttat
    29881 caattggctc atcttggagt gaaatccgga gacaaagtta ttatttataa gagttccgct
    29941 tttgacacat accttctagc tgtttctgtg tcttaccttg gtgcagtgcc tgtcatgact
    30001 tcttatcatc taccaacaac aacaatggaa gtatttatcg atcgtttaga agaccctttc
    30061 attttatttg atgatgagac aaaaaagcga gtgagagaaa tttcaaatgg aacaaaatca
    30121 aaacagattc ctattcttta tttaatggaa caacctgctt tgtctgtttc tcaatcattt
    30181 ttagacaaaa atgaaatttc ttatatgacc catacttctg gtacaactgg tatccctaaa
    30241 cttatttgtc attctgctca ttctatggga tggcggacga aatggcaaaa aacagttttc
    30301 acaaaaattt cggaaaagaa attaatcgct tttcacatct ctccagtgca ttccagattc
    30361 aatattggta tctcttcttt gatgtccatg ggatttccta tgatgccttt agcaaacgca
    30421 caaagttcaa aagttgttca tatgttggaa gctcaccggc caattgcact agagacccat
    30481 ccgaataact ttgttcagtg gcgttttact gctaaggagc atccagaagc tttttcgggt
    30541 atccgatact atcactccac ttttgatgct ataaacaacc agacaatgaa gacatttttg
    30601 cgaacgtcga tggcacagga tgcggtattt cttcaagtat atggccaaag tgaatgcgga
    30661 ccaatgattc ttaaggctca tacactagag agtttgaaaa caagtgatgc aagagatatg
    30721 ggcgttggac tggaagacat gacaagcgct cggattacag attcagttgg gaatgtccta
    30781 cctgaaaaca cagatggtca tatacaatta ctgtctaaag gacgggcttt gacttattac
    30841 aaggaagatg cacggttcca ggaaaatgtt tatggcgatt ggtgggatag cggagattac
    30901 ggttttatgg ataagcatgg ccacctattt ttgaaagatc ggcaagtgga tttgatcgaa
    30961 acgatcaata gtacattagc tattgaagac tttttattag attcgttaga ttttttggca
    31021 gaagtagtga ttgtaaggga taaaaatcat tctccacaac cgattattgc tttagctcct
    31081 gataaagaaa tggattggaa tcgatggtgg gagcaagtcc atgaacttcc tcgcttgaac
    31141 gtccctatca tccgtgattt tgatgcaatc ccgcgaacag ctacaatgaa agtgcaacgg
    31201 cttcaaatcg agaaagaatt aaaatcacaa aagtcctaac tatttaagga aagaaagatc
    31261 cattttggtc tttcttttct ttttgttttt ttaaattgga tgagataaaa atatgccaat
    31321 tggctgtttt tcttttttga aaatttcgtt atactcttat tcatggagga aaatgttatg
    31381 aaaagaatct tgacaattgg cggttctgat ccatttgctg gtggaggaat ccaaacagat
    31441 ttaaaaactt ttgagaattt tggtctattc ggactaagcg ccttgacttc tataggggca
    31501 ctagatatta atgagcgatt tatgctggaa tctatatctt tggaattgct taaacgacag
    31561 ttagtttcga ttgataaaat gacttcatta gatggtatca aaattgggtt attgaattca
    31621 agtgaagcaa tcatggttgt tcgagacttc ataaaaacaa aacaaaatat cccaatcatt
    31681 ttagaccctg ttttggcatt caaagaaact gaagctgtga tcaatcaatt gtatatttcg
    31741 cagctcatcg aagaactttt tccacttgtt acgatgatta cgcctaattt ggcagaagct
    31801 gctttacttt ctggtcaagc tcttccctct tcgttaacag aaatgatcca tctcgctaaa
    31861 gaactcactg cttcaggaac aaaaaacatt gtgatcaaag gcggcacaag gatggctgga
    31921 gatgaagctg tggatcttct ctattcaatt gatcattatg aggtattttc tcataaaaaa
    31981 atcgacacta caacagtaaa cggggccggt tgtgcctttt cttctgcaat aacagcgaat
    32041 cttgtgttag gggcagattt taccaaagca gtagcagaaa gtaaaaaatt tgttgcccat
    32101 tgtatttcta atggcgtgct gatgaacgat cataccggaa gtgtctggtc tggcggtatt
    32161 caaaaaggag gaatgagaaa tgaaaactaa gcaattaacg atctatgcta tgctgattgc
    32221 gttgacagtt gccctttcat taacaatttt gatccctgta ccggctacga atggatttgt
    32281 gacattatgc gaggccggga tctataccgc tgcttttctt tatggtccaa cgggtggatt
    32341 agttgttggt gcttccagtg gtctattgat cgatttgatt tcaggatatc cgcagtgggc
    32401 agttttttca ttagtgatcc acgggttaca aggatatgtt gctggttctt tcagcaaatc
    32461 ttctactcgt atgtggggat tagggctttt attaggaagc ttagttatga tcatcggcta
    32521 tggtatcgcc ggttggattt tatatgattg gccggctgga gtggcttcta taccaggaaa
    32581 catcttccaa aatctgattg gaatgggact tgcctttcct ataactgcaa gtcttcaacg
    32641 tattcaagca cggaagcaat attaattgaa aaagaaggtt ttagaaaatg aagttgtcag
    32701 aaaaagaatt aaaagaccaa ttgactgaaa tagttaatga catattggct gaggcacact
    32761 tgaaaaaagg tgatcttttt gttttaggat gcagcacaag cgaagtcgtt ggaggacata
    32821 ttggaaaaaa ttccagtgcg gaagttggtc aatggatcat ccgtacgtta aaagagttgt
    32881 tggatcctaa agaaattgcg ctagctgtcc aaggttgtga acatttgaac cgagcattag
    32941 tagtagaacg aacagtggca gaagcaaaaa atttcgaaat tgtctctgtt gttcctgcac
    33001 tacatgctgg aggtgcttgt tctgttgctg cttttgacca gttcaatgat cctgtcgaag
    33061 tggaacacgt agttggacaa gccggtatcg atatcggtga cacatcaatc ggtatgcata
    33121 tcaagcatgt ccaagtacct gtcagacctc gtttgaaaac ccttggacaa gctcacgtga
    33181 cagcccttcg ctctcgtcct aaatatatcg gtggtcctag agcgaattat tgaaatgagt
    33241 aattgacaga gcaatctgaa aaacttcctc gcaaagtcca actaatgaac tttaacgagg
    33301 aagttttact tgtttgtttt atataaccga gcttcataag gtgctagtat gcctttagct
    33361 tcaaattctc cgctagagga atttgacaag agtaatgtcc aggactgatc tgcttctttt
    33421 ggaagttcat agtcagcaag tgattctgtt aagtttacca taataagata ttgttcatct
    33481 tctaaatatc tttcatagac ataaagttgt ggatgttcat gaagatattc tttataagaa
    33541 ccgtatatca gacctttatt ggtttgtcta atgcggatca tgttcttata gaattgcagg
    33601 accgactctg gttcatattc ttgttgttct acattgatcg ttttggtatt tggattagtg
    33661 atcagccaag gttcatgtgt agaaaaacca gcatattgtt ccgaagtcca ttgcatgggt
    33721 gtcctgctgt tgtctctcgt tgtttcacga atgatatcca atgcttcttc tcttgtctta
    33781 ccttccgcaa gcagcctttt ataaagtctt ttcgaatcta ctgcatcaac ttgatcgatc
    33841 gattcaaagg gcatattcgt cattccgatt tcctgtcctt gataaataaa tggcgtacct
    33901 tgcaaaaaga aatacatcat agcgattgct tttgcagaca tagcccaaaa atcgggacga
    33961 gtatctccaa acactgaaac ggcacgagga acatcatggt tttccatata taaagcgttc
    34021 catccgatac catccaatga agtttgccaa gcgcttaatg catgtttcaa tttaaggaca
    34081 tctaattgcc cttctttttc ttgctgccag atatggatat gatcaaattc gaatatcata
    34141 tcgaaataac cgtctttccc tacccattgt ggtccttctt ctgcagtgac accacttgct
    34201 tctccgacag tcatgatatc gtactcttca aaaacatgtt tcaaatcggt caaatgttct
    34261 tcgattcctg agacattttg aaagggtgag aaagggttct ctgtggcttt tactgaatat
    34321 tcatcttttt ttacatgaga aatcgcatct aaacgaaatc catctatccc tttatccaac
    34381 caccatcgga tcatattgaa tagttcttct ttcaatttct cgctttccca atttaagtct
    34441 ggttgttctt ttgcaaaaac atgcagataa tactgtccag tttcatgaga atactcccaa
    34501 gcagaaccgc cgaaaatcga tgtccaatta ttcggttctt tgccatctac cccgtcgacc
    34561 caaatgtaat aatcgcgata cgggctttct ttagattttt tcgattcttc aaaccattga
    34621 tgctgatccg aactatggtt gatgacaaga tccataatca ctttgatccc taattcatgt
    34681 gcttctttta gcaataaatc aaaatcttcc atcgttccga atctctcttc tatatcttga
    34741 tagtcactta cgtcataacc attatcgaca aatggagatt gatagatcgg attgatccag
    34801 ataaagccga taccaagatc tttcaaataa ttaagttttt cacggatccc attgatgtct
    34861 ccttgaccat cgccattgct atctttgaaa ctagcaggat agatttgata gcctactgct
    34921 tctttccacc atttttgttc ttgtatcata tcgtttcact cctttaacgg tccctcttga
    34981 ttataaccga ttctatttta gaagtatcct tgttaccggt aactagaaac gaaaagctca
    35041 acgaatctgc taagtgcgtt cgctgagctt tattttatca tagatagcgg gcaatcagtt
    35101 gaatcatttg cttgggaaat tcattcaagt cagtaatatc tacaaaacga ctttcaccgt
    35161 agatcgactt gatttcttct ttgtcttggc caatagctgc ggagacaaat aggattcctt
    35221 gacgttcata ttctttcaaa acagactgga tatcttcttt tgcttttttg cctgtataat
    35281 ccggcaacgc ttttggctga ccgtcactaa tattaagcaa cagtttggtt gttgcggatt
    35341 gtctgtttaa tttttctgct gctaaacgaa gtgcagcacc atcacgattg ttttgccttg
    35401 gtttcatagt gactaatttt tcatttaacc attgaaatcc gtcttcaaat tctttataag
    35461 aaaacaaaga agtcttttct cttgacgaac ggtctgctgt atctccgtaa atcaacaatg
    35521 ggatatcgac tttcttagaa aattcggcaa tggcaatcgc tgcttttttt gccgcttcga
    35581 tccgatcatc ccgtatcatt gacccagatt catcgatccg tacagctacc gctaaagaag
    35641 gttgctcatg tggcgggttc tttttgtcaa aatttctcaa atcaccatat gctactttgc
    35701 ttgcattgaa ccgctgacct tcgtattttc ctttttggta cgtctctgtt tgttcattat
    35761 ccagtaactc taaaatttgc cggctaagtg attctactat tggcattact tgcatgtgta
    35821 gctcacgtgc ttccggcgtt tttccttgga aagctggtcg gtgaacgatg agaccttctt
    35881 tttcatgaat cgtttccttc atgatttgtc gcgcttcttt attcagttgc ttcttgattt
    35941 ccttatcatg tgcttccatg tcagaagcag acatttcttg agaatcatct cctgtttgtt
    36001 gttctttttg attttttcct tcgatatcgc tactgcgttc tttttgcatt tgaggaggaa
    36061 tctcgttttt ttctattgtt tcttcttgtt tctcttctcc ctcatttggt tcttcagcag
    36121 acaacgattt cttttcatct aagcgcagaa tttcttcagc attttcagtg atgtttcgtt
    36181 catttgcttc ttcggcgcta atggttcttt cttttgtatg ctcagattga ggatgacccc
    36241 atttttcttt tctcaatatg tcctgaagtt ccagtagcaa tccactgtca gacaaagctt
    36301 gttcaagaat tgccaattca tctgaatcag tggataattt atacaaaact tttggataaa
    36361 tcgactggag taaatcttgt ccttgcttat aggtatttgc ccaataaaaa taagaacgca
    36421 ttcctgctac acctttgatg gcgttagctt ttgcagtttc atccaacaaa cggataatct
    36481 ctgccatctt taagagaagt tcttgttttt ggatcatagt tttcgccatc gcacgttctg
    36541 ccatgacttc taaggcagga agatccattt tttccgcatg ttgcatccga tctcttaaag
    36601 attcatttaa tgggcgattt ccttggtaat ttcgatttgt agtgatcaca atgacgcaat
    36661 ctggatggcg acgaatgatt cctgtcggta aattcaacat cccatttggt tcgagcgctg
    36721 agttaagtgc cacaagaaca gaggcatctc ggatgacagt cggctcttga atctctaata
    36781 aatagccttt ttcaatcgct cgaacgattt cagaagggta atagctgtaa tggattgcat
    36841 ctggataatc agcttcgatc ctttgaacta gctctgctaa tttttcttta gcagaaaaag
    36901 gatcaatgcc gtaatggttc tggatcagtg tcagtacagc ttcaagtgta tctgtttggt
    36961 aaatagcttc tagtaattct tggtcttgtt ccttattaga atctactaca ggtaataagg
    37021 ctccgaaaac atctgatttg tccatatctg caaaacaggt cacttttgta tagggaagtt
    37081 gcagatcagc agatagtgct ttggctaatt gtgtcttccc cgacccggca tctccttcca
    37141 aaagtacgtt actgattttc atttcaggat cttgccaatt ccctttgatt tcggaggcga
    37201 tccgccattc ttctgcactt gtccgatggc ttttcggttt cttccagatc atttgctttt
    37261 ctagccgtga aaaggttcgg ttttctgtta gtgagaaatt ctccatgctt ctcttcccct
    37321 tttgatcatc tctgtctatt aatatcctag ctcatctaaa agacgtttta aaatacggaa
    37381 tcgttcccca atcagttctc cgtctttttg tagtgtatcg taatacaaaa tgatgtcttc
    37441 atcgatcttt ggatttttgg tatctacttc taccgtcatt cggttccctt gtaatccaat
    37501 gatgtctacg actggatttt ctggatcata aaatttttca taacgataag catcttggaa
    37561 gtataaactt ccttgcgcag ctaagatcgc taaatctaaa atacgtgtga ttggtaattc
    37621 ttccgactgt cgtgaccatt tttctccagt atgtcgccat accttgcctg agatatcgac
    37681 ttttccacga tcattccact gagcaaggcc cagtgaaagc ccttttgcat ccatatttaa
    37741 tgcatttctt ccatcaactt tatcatagtc ttctacaacg attactggtt tatgttttaa
    37801 atttgttggt atttccatta ttttaactcc tcatcctttt atttttagta aataagtaaa
    37861 ttagtagttt actcatttac taaactatat gcgacattat agaggattga agtgaggatt
    37921 gcaaagaaaa agagcttcat tgatagaaat aaaaacacca tctcgttctt ttacacgctc
    37981 attagtaaca tgtagaaagt ccaagatgat gttggaatat tt
//
LOCUS       DAIGQM010000021        36703 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.021, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000021 DAIGQM010000000
VERSION     DAIGQM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.021"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            647..964
                     /locus_tag="NOA48_001063"
     CDS             647..964
                     /locus_tag="NOA48_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0789341.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="NOA48_001064"
     CDS             complement(1055..1420)
                     /locus_tag="NOA48_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789342.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="NOA48_001065"
     CDS             1628..2110
                     /locus_tag="NOA48_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789343.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="NOA48_001066"
     CDS             2307..3197
                     /locus_tag="NOA48_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCI0789344.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="NOA48_001067"
     CDS             complement(3484..4758)
                     /locus_tag="NOA48_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0789345.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="NOA48_001068"
     CDS             5031..7502
                     /locus_tag="NOA48_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0789346.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="NOA48_001069"
     CDS             complement(7605..9341)
                     /locus_tag="NOA48_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCI0789347.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="NOA48_001070"
     CDS             complement(9338..10042)
                     /locus_tag="NOA48_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0789348.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="NOA48_001071"
     CDS             10173..10676
                     /locus_tag="NOA48_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCI0789349.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="NOA48_001072"
     CDS             10636..10974
                     /locus_tag="NOA48_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCI0789350.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="NOA48_001073"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="NOA48_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCI0789351.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="NOA48_001074"
     CDS             12525..13103
                     /locus_tag="NOA48_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCI0789352.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13055..13627
                     /locus_tag="NOA48_001075"
     CDS             13055..13627
                     /locus_tag="NOA48_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0789353.1"
                     /translation="MFPQRRGRTYRQKGRIKHAKIIFYGAISLDGYLATKTDDLQWLF
                     DTPTGKQTTYEAFYETIDTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPD
                     AEVVNEDPVAFLKNLQMTEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIP
                     LFQKGTYEARFEMLDTTRFGEFIELHYVRK"
     gene            complement(13706..14260)
                     /locus_tag="NOA48_001076"
     CDS             complement(13706..14260)
                     /locus_tag="NOA48_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0789354.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14513..14788
                     /gene="rpsP"
                     /locus_tag="NOA48_001077"
     CDS             14513..14788
                     /gene="rpsP"
                     /locus_tag="NOA48_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCI0789355.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14800..15051
                     /locus_tag="NOA48_001078"
     CDS             14800..15051
                     /locus_tag="NOA48_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCI0789356.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15176..15967
                     /locus_tag="NOA48_001079"
     CDS             15176..15967
                     /locus_tag="NOA48_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789357.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16137..16658
                     /gene="rimM"
                     /locus_tag="NOA48_001080"
     CDS             16137..16658
                     /gene="rimM"
                     /locus_tag="NOA48_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCI0789358.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16648..17409
                     /gene="trmD"
                     /locus_tag="NOA48_001081"
     CDS             16648..17409
                     /gene="trmD"
                     /locus_tag="NOA48_001081"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCI0789359.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17545..17892
                     /gene="rplS"
                     /locus_tag="NOA48_001082"
     CDS             17545..17892
                     /gene="rplS"
                     /locus_tag="NOA48_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCI0789360.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18150..18443
                     /locus_tag="NOA48_001083"
     CDS             18150..18443
                     /locus_tag="NOA48_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCI0789361.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19286..21613
                     /locus_tag="NOA48_001084"
     CDS             19286..21613
                     /locus_tag="NOA48_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0789362.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21739..22068
                     /locus_tag="NOA48_001085"
     CDS             21739..22068
                     /locus_tag="NOA48_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI0789363.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTIDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            22108..23112
                     /locus_tag="NOA48_001086"
     CDS             22108..23112
                     /locus_tag="NOA48_001086"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0789364.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            23109..24538
                     /locus_tag="NOA48_001087"
                     /pseudo
     CDS             23109..24538
                     /locus_tag="NOA48_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24744..25916
                     /locus_tag="NOA48_001088"
     CDS             24744..25916
                     /locus_tag="NOA48_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0789365.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(26078..26533)
                     /locus_tag="NOA48_001089"
     CDS             complement(26078..26533)
                     /locus_tag="NOA48_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789366.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            27123..27545
                     /locus_tag="NOA48_001090"
     CDS             27123..27545
                     /locus_tag="NOA48_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789367.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(27711..28904)
                     /locus_tag="NOA48_001091"
     CDS             complement(27711..28904)
                     /locus_tag="NOA48_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0789368.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            29128..29505
                     /locus_tag="NOA48_001092"
     CDS             29128..29505
                     /locus_tag="NOA48_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0789369.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            29493..29831
                     /locus_tag="NOA48_001093"
     CDS             29493..29831
                     /locus_tag="NOA48_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0789370.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29965..30408
                     /locus_tag="NOA48_001094"
     CDS             29965..30408
                     /locus_tag="NOA48_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI0789371.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            30670..31485
                     /locus_tag="NOA48_001095"
     CDS             30670..31485
                     /locus_tag="NOA48_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0789372.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            31495..32157
                     /locus_tag="NOA48_001096"
     CDS             31495..32157
                     /locus_tag="NOA48_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0789373.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            32362..34026
                     /gene="alsS"
                     /locus_tag="NOA48_001097"
     CDS             32362..34026
                     /gene="alsS"
                     /locus_tag="NOA48_001097"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCI0789374.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            34039..34749
                     /gene="budA"
                     /locus_tag="NOA48_001098"
     CDS             34039..34749
                     /gene="budA"
                     /locus_tag="NOA48_001098"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCI0789375.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34879..35376
                     /locus_tag="NOA48_001099"
     CDS             34879..35376
                     /locus_tag="NOA48_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCI0789376.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            35561..35821
                     /locus_tag="NOA48_001100"
     CDS             35561..35821
                     /locus_tag="NOA48_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789377.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(36183..36422)
                     /locus_tag="NOA48_001101"
     CDS             complement(36183..36422)
                     /locus_tag="NOA48_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789378.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT        12339 a         6418 c         7303 g        10643 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactat gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatattaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaatcata ttttatggtg ctataagttt
    13141 agatggctat ttggcaacga aaacggatga tcttcaatgg ctttttgaca ctccaacagg
    13201 taagcaaacc acttatgaag ctttttatga aacaatcgat acgaccatca tgggcagaaa
    13261 aacttatcag gaagcaaaaa aatatttgga gaccgaagca atttatccag agaaaaagaa
    13321 tttcgttttt tccacccacg cacaattaca attgccagat gctgaggtcg taaacgaaga
    13381 tcctgttgct tttctaaaaa atctacaaat gacagaagga aaagatatct gggttgtggg
    13441 tggcggtcga ttgatcaaac cgctattgga acatcaaatg attgatgaat ggtatatcca
    13501 gattacccct gtattattag gggacgggat tcctttattc caaaaaggaa catatgaagc
    13561 gcgttttgaa atgctagaca cgacacgatt cggtgaattt atcgaattgc attatgtacg
    13621 aaagtagaag taaataaaat aaaaaaggca actatatgca gaaatgtcct gtacatagtt
    13681 gcctttttta ttaccgttat gctttttact ctgttaattt gttagaaaaa tctagatacg
    13741 catctaaaat cgtttggaag aaacttaatg ttccttcaac gatattacca ttttcatcaa
    13801 ttagattcgc aacgtttccg atatatgctt ccggttgctg caaggttggc acattcaaaa
    13861 agacaagtga ttggcgtaga tggtggtttg cgccaaagcc gccgatccca cctggtgatg
    13921 cagtaacgac taaacctggt ttatgatccc aaacactgtg tccataaggt cttgagccta
    13981 catctaaagc atttttcaat actgctggca cagaacggtt gtattcagga gtaacgaaaa
    14041 cgacaccgtc tagtcccctc acttcctcac gaaaacgagt ccattcagca ggagcctgtt
    14101 ctggagtttc gagatcctca ttgtaaaatg gcagatcatc gatttttaca aatacacttt
    14161 cgtacccttc aggaagcaat ttcgcaaaag cttctgctac ttttttgttg taagaatctt
    14221 ttcttaaact accaataaaa aatccaattt tttttgtcat acgatttttc ctccttcaaa
    14281 ctatctataa taatcttaca aaagataagt aactggagca aataaaaaca cttactgaca
    14341 aaagctacat agaagataga ttacttattt ttaacaaaaa agaagtctaa aatcttctat
    14401 tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa aaagctttac agggtaaaaa
    14461 aaaactgtta cactacatct tgtgaataaa acaatggagg tggaaataaa taatggcagt
    14521 taaaatccgt ttaaaacgta tgggttctaa aaagagtccg ttttaccgta tcgtcgtagc
    14581 tgattcacgt tctcctcgtg atggacgttt catcgaaact gtaggtactt acaatccttt
    14641 gaaagaccct gcagaagtag ttttaaaaga agacttagtt cttgactggt tatcaaaagg
    14701 tgcacaacct tctgacactg tacgtaacat cctttcaaaa gaaggcgtta tgcaaaaaca
    14761 ccacgaagct aaattctcaa agaaataagg tgaccggata tgaaagattt aagcgactta
    14821 gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc aagtcaagtt agacgtcgta
    14881 gagtcgaaag acttttacga gtacaatcta acagtggctc ctgaagatat tggccgtatc
    14941 attggaaaac aagggcgtgt tgctaaagca atccgcacaa tcgtttacgg tgttcggatc
    15001 aatgcaccga aaaaagtgcg tttgaatatc atcgatgata aggaaaagta aataaacgtg
    15061 ctgtactcga attttcgagt gcagcttttt tgtttttttt attaattgaa gaaatgatta
    15121 tttggcaaaa caagcaagaa agcgtatcct tataggagga gggagtgaac agccaatgag
    15181 aaagaaaatg ttatttattc catttgctct attgttaagc gcttgtagtt cggttactca
    15241 agaatcagac aatacacatc tatcaagcag tatatctgaa actgttacca gtccagaaaa
    15301 aagtagtacc aaaacggctt ccaccactga acaaacaatg gctacctcaa ataatgagaa
    15361 aaagactgct ttagaccagt tgaaagaaca acagccaaat gttcccatgc ctctagatgt
    15421 accagtctct tcaggctatc tcaatatcgc agcgacacat acaaagcaag gttattctat
    15481 tttatattac agaacagatc gtcccctcgg gttgaatgct gacgaattga atcaagaaac
    15541 gcctattgca acctatctat atcaatatgg gtttgcttct agtcaagaaa caatccaagt
    15601 tttgcagcca tttgagatcg acacaaatgg tcagcaagtg gacttaggtt ctcgaatcac
    15661 agggtatcag caaggtgcag caggttcaag ttttcttgaa tggcaagaag gaaactggcg
    15721 tattcgaatc cgtgggaata atatagaagg ccaagatccc ttactattag ctaaagaaat
    15781 cgtagcttat ttggaagaaa acagtctacc agcacctgaa caatttggta aaattactgt
    15841 tgatatgggt gatacgacga atcgagccgt agaagtaagc tggcaagaac cgaaaaatgc
    15901 ctatacgatc actcatcaag atcctatgtc tgcgttgaag atggcagttt ctatgaagag
    15961 gttgtgaaat cagcgcgctg atctgagccc atcatttaac tccaagtcac aggaagtaat
    16021 caaaaatagc acgccgcatt tttgcataat tttggcttaa taccttaaaa gaaaactaga
    16081 attgcctctt cacacatgct aaaataaaac agacaaaaaa gaaatgggga tataagttga
    16141 ctgaatactt gaatgtagga aaaatcgtaa acacacaagg tatcaaaggc gaagtccgtg
    16201 ttatctcaac aacggatttc ccagaagaac gttacaaaaa aggaacggtg ctaacactat
    16261 tccaagacgg aaaagcacct gtggaattaa cagtcaaaag tcatcgcaaa cataaaaatt
    16321 ttgacttatt gagttttgaa ggacatcctt ctatcaatga tgtggaaaaa tatcgggatg
    16381 gcatattaaa agtgtcaaaa gacaactctg tagatctagc tgaaaatgaa ttctattacc
    16441 atgagatcat cggtctgcat gtattagaag atggaactga gttaggtaaa gtaaaagaaa
    16501 tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg tccgaaaaaa gctgatatat
    16561 tgcttccata tatcgcttct gtcgtcaaag aagtcgattt agaagctgga gtggtccgtg
    16621 tagaaattcc agaaggactg attgacgatg aagattgatg tattgacttt atttccaaga
    16681 atgtttgaag gtcctatggg ggaatccatc atcggtaagg ctgtagataa aggattatta
    16741 gatatcaata tctctaactt ccgcgattat tcagataaca aacatcagac agtagatgat
    16801 tatccatacg gcggtggagc aggtatgctg ctcaaagtcc agcccatcta tgataacatc
    16861 caagccattg aaaaagctgc accggatgtc aaaaaaagag taattcttct tgacccagct
    16921 ggtaaacgat tcgatcagaa aatggcagaa gaattttcac aagaagaaca cttagtattc
    16981 atttgtggtc attatgaggg atatgatgaa cgtatccgca cattagtgac agatgaagtt
    17041 tccttaggag attatgtcct tactggggga gaattaggtg cgatggtcat gatcgatgca
    17101 acagttcggc ttttgccaga tgtgttaggg aatcagactt cagctcaaac ggattcttat
    17161 tcaaccggtt tattggaaca tccccaatat actcgcccgg cagaatataa agggatgaaa
    17221 gtaccagaag tattgacaaa tggaaatcat aaattgattg aagaatggca attaaaagaa
    17281 tcactaagaa ggacctatca acgtcggcct gatcttttgg aaacacttga atggacacct
    17341 caaatgacga aatttttaga agaaatcaag aaagaagaac aagaaaaaac agcagatgaa
    17401 gccaagtgac tttttctaaa atcttcttta cagtaggttg ataatatgtt agtattttat
    17461 ggtgagtgca aaagcactta actattacga tattccgctg tgagaaaagc tcataagaat
    17521 atttggaata aggagaagaa aaccatgaat ccattaatcg aagaattaac aaaagaacaa
    17581 ttacgttctg acatcccagc gttccgccct ggtgacactg tgcgtgttca cgcaaaagtt
    17641 gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg ttgttatcaa acgccgcggt
    17701 gctggaatca gcgaaactta tacagtacgt aaagtttcta acggagtggg cgttgaacgt
    17761 acattcccat tgcatacacc acgtgttgca aaaatcgaag tagttcgcta cggtaaagta
    17821 cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa aagctgctcg tatcaaagaa
    17881 atccgtcgtt aatcattgtt atcagactga gaaagaaccc ttggtattca agggttcttt
    17941 tttcttagca tgtaatttga acaccctgat ccagtttttt ctttaattat tggtagggga
    18001 gaataatgga ttagaataaa tctacctata agtagtagta aaaaaaagag cactatgata
    18061 atatctttct taagagtaac cgctttaata aaaaatccag aatattctaa cataaatgga
    18121 gtattcttag aatcaaaagg agaaagaaga tggtttatac ttatacggag caagaaaaga
    18181 tgaaagtttt agacacattc atgaatgatg gaaaagtaaa acaagtacca agttcaacaa
    18241 aaaagaaata catcctattg aaagaagtct tgaaacgctt tgaccatgga gtgacttata
    18301 cagaaacaga ggttaattcg atactgctga acgtattttc tagtggcgat tatgtcgaac
    18361 aaagacgtta tctaatcaca tttggctttt tcaaaagaag ttcagacggt cgggcatatc
    18421 agatgatggg aattgaaaat tagaagtttt aatttatact cattgaaaaa agttcaagta
    18481 tgcgatattg gttctacacc gcatacttga actttttttg tcatctgtat ctataataca
    18541 aagccaagaa cgttattcaa aatatggata gctatgataa aagctaatga gcgattcgca
    18601 gttaaataag caatcgtcag taaaatcgtt ccaggagcgt acatgaaaaa atcaattgga
    18661 tgcgttacat gaataaagat aattctcttt tatttgtacg aataaatacc aaaacgtacc
    18721 tcctaaaatt agattttgga cagatgccct ttaaaaagat aacaagattt cgttcttgaa
    18781 acaatatata tgcttttatt ccaatgaggt tgtgaaaaca gtattttgtc ctgagcgtta
    18841 gaaaattgaa aatggggaat agcaactcgt actttaccat tttttaagtg aatacaagat
    18901 cagctaattg aacaccgttt attcgtgatg agggacacaa cactgcagtc gacacatttc
    18961 tcttttatgt tcaaagataa caaatattta aaacaaagaa aaatagtaga taatcccgtc
    19021 ctaactcttt tattcttccc tcatagcttc caaatttaag caatacttca attaatcaag
    19081 ttttatcttt ttttttcaat aatcgtaaaa aaagagtatt ttttatttaa aaataaaatc
    19141 tttgtattaa aggacaagac taaaataacc ttagaataaa aagagaaaaa aagccccaaa
    19201 ctttctatac atcaataaaa taataaaaat taaatttaga ataacgtgta aaggattatt
    19261 tgatgatttt ttattgagag gagggatgaa aatgattaag aaaactcaaa ataaaatcca
    19321 acgtatatgt caaaaacatt ttgtttctag actcaaagct gtatctaaaa gaaaatactt
    19381 acatcccatt atgatttcga tcatcttgat ttttactttc ttagggagct tatcaagtat
    19441 ttatgtaaac gtttatacag aaacgtcaaa ttttgctaac caaacgacag aggagacaaa
    19501 tagtccaccc tattctgaaa tacagtccat agaaagcacc aatcagtcta gcaacaacga
    19561 gacaacctca accacatcct cgactcaact gattgatccg acagaaaaag aaatcacagc
    19621 agcaaaagca gcaggggaga aagcttattc agaaacaggt agaagccaga catttagtac
    19681 tgttgcggcc actgcgaatt tcaacggaca taccatacca gatggatata cagtgatata
    19741 tgccaaagat ggagtcattg ttgcggttaa cggatcgatg agtgcggata aaactgcgtt
    19801 acaaggcgta accaaagcaa tcgcttttat tgataaccgt ccagatatcc ataatctgtt
    19861 tattggctcc acagtaaatg gtactactat cacattccca aaaagtatct atatgggggt
    19921 ggctaccgct ggaaatacga tcgattcagt tacacccaat gcggataaaa gttattcttt
    19981 tacaccctca acatggggag ggcttcctgc cggaggaggt atgagtactt tttcaatcgg
    20041 tatacagtta gcaaatgata ttccattcac ggggtactcg atcaaaaatg ggcagatcgt
    20101 tgatggtaag ggaaatgttt caaattttcc aacctatcaa gcagcaacgg ttcaggtcaa
    20161 tgcgaatcgg acaggaactt tttcttatac agtcaatggt ggagcagcaa aaatcggaac
    20221 gtacgggact acattatctg gaatccatgt gggtgacaaa gtggttatca ctccaacagc
    20281 agtaacgggc tattcttttg cacaaacaaa cggttctttc acagccctag aaagtaacgt
    20341 cgatacggtg acctatacag gcaaacaaac accaatcact attaagtatc aagactattt
    20401 tggacagatg attgctcctt ctaaaataat gaatcttact tacggaagtg ctgcacaaga
    20461 cctgacgact aatacgccta ctatcaacgg atataccttt acagctgttt cagcgacaga
    20521 aacaaagaac caatcagcaa tgagtgtttt agctagttta gatacaaatg gaaatgtaat
    20581 cgtaaaggac gcaaatggaa aacagatttc tgaagtcatc ctatattata agacaaatgc
    20641 aacagtatca atcaatgcaa atggcagtaa gtactatgat ggtctttctg ttgtaccgat
    20701 cgttaaatat gcctttaatg ataaaacaga atcaacatcc cttttaaaca atgatctcag
    20761 tattgatcaa atcacatgga atccaactga tttcaaagcg atgaatgaaa agggagttga
    20821 agtaactgcg cctactgaaa ttggaaccta tacgtcttgg caattgacaa aaagcggact
    20881 agctaaacta gctgccagaa caaactattt atttactatc gtgcagacat ctgatgtcta
    20941 tacgattaag caaatcagcg gtgcggtaga gctcagtggc agtaagacat atgatggaaa
    21001 agcaggtgtc ccgtcaatcc atgtcaagct agcagagggt gtcactagtt cgcttactcc
    21061 agtacaagtg gcacttagca gtatggatta cacagcagat gcacaatcag caaaaaatat
    21121 ggttaatgct ggcagctata caattaaact aacgaatagc ggaatagaca aagtcaaagc
    21181 agcaaatccc aagttgtcat ttactgatat agccaacaca tcaggaactt ataccatcta
    21241 taaagctaac gcagtgatta ctgtcgatga cgctgccttt aattatgatg cccaaagtca
    21301 ctcgatttcg gttggaaatc tccacgttac cggtgttgtc ttaggcgaat cattggatta
    21361 taccctaaca gttaacagcc ggacagatat tggatcacaa atagtaacga ttagtttagg
    21421 cgaaggaagt gtaaacaata attatacgat tatcgcaaca gataccgcta agttgacgat
    21481 caatccgact ctcttgcttc cttcgacagg tgggataggt ctactgccct ttgtcttttt
    21541 aggactgatc tttatttttt ctggcttctt ttattttatc catcgtaaga aaaaagcagg
    21601 tgaacagcga tgaaaaaaac aaaaaatgta cgtgtggata tatttgctgt tctctttttt
    21661 atcctactgg tcttttttat aggttctccg actgtgtcag ctagagaatc acctattaca
    21721 tttactttgc ataatcgaat gttcgaaagc gataagatgc caagtatcag tcaaaacgac
    21781 ggaataaata tcccggataa ctttcaagga gtaaaagggt tgaacggcgt tactttcgct
    21841 atatatgatg tctcggatga attttacaag ctgcggtcag aaggaagtag tgtggaagac
    21901 gcacaaagaa aactagcaca aaaaagtgat agtgaaaaaa tactggcaga aaatgtgaca
    21961 aaaacaatag acgaggaaga gggcattgct tcttttagtg catcggacaa agatgagcaa
    22021 ggtcgtgacg ctgtttaccg atttgcggaa ataaagactt cagattaagt aaaagaaaaa
    22081 tcagcaccat ttgtcgttgt gcttcctgtg acagattcat ctaatcataa attgacgacc
    22141 atccacttgt atccaaagag cgaacaaaaa atacctgctg cactcacatt aacaaaaaca
    22201 gtagagaata agcagacaga ttttgcagat ggggataaag ttccttatct catcaccgta
    22261 acaattcctg agaacatcaa cgagatagga acctatacga tcaaagatac agctgatcct
    22321 cagttatggc tagaaccaga aacgatcgat tttttgattg gtggagacaa gattcataca
    22381 tttcacacac aaaaaacaaa acatggtttt gtcttatcag attctggaaa agatcttagt
    22441 tcgtttgctg ggaaaaaatt aacgatccgt taccaaatga cattgaaaga aaacagtgaa
    22501 aaaacgacat ttgataacga tgtacgtttg acgactgaca atcaaacagt agaaacacat
    22561 cttgccatcc aaacaggagg caaacaattt gtcaaagtgg atcggcaaac gaaacaaaaa
    22621 ctagcagatg ctcaatttct agtcaaaaaa aatgaccaat acttagcgca agaaaacggg
    22681 ataaatcatt gggtagccaa agatgattca agagcaacga tttttacttc cagtaaagat
    22741 ggaacatttt ctgtccatgg attgtctttt ggaagttacg aactagtgga gattaaaccg
    22801 cctaaaggat atatattgag tcaatcaacc attctctttg aagttgaaaa aggcagttat
    22861 gatccgcttc atcctatacc attggaaatc atcaacgaac caaaagcaaa tccgacgaat
    22921 aatggaaaaa cgccagttca gatgcagaca aatggtccat caaatgaaaa aaatggagga
    22981 agctttccaa aaacaagcga agagatgctt ggaggtttct caattttagg gttgttgcta
    23041 gtcctttcaa cagggacagc ttggttttat aaaaaacaac aaaaaggaaa caataggagg
    23101 gaaataaaat gaaaaacatc aaaacaaaaa tatggacgtt tttaggaact gctatcatgc
    23161 tgcttccttt cgttctcggc ctaggaactg cagaggtttc taggccgtat cacctacacc
    23221 agaaaatgtt acggttaatt tgcataaatt gaaattcact tcagcaccag aaaatcaaat
    23281 aaacaacgga acggaattga catttccgaa tagcgaaccg ttgaacggcg ttgaattcaa
    23341 cgtatatgac atcactgcta cgtactatcc aagtaaagac acagcagttc cagcagacgc
    23401 tacacccttc gcaagtgtaa cgacttctgg tgaaggatta gctaacctga ctcttccagg
    23461 taaatctgat gggaaagatg ctgtatacgt ctttgtagaa acaccaaagc ccggtgtcga
    23521 aacgtcgcca aatatcgtgt taagcttacc cttttataac ccgaattcat cagaccctga
    23581 caaaccttta gacacgattc acctatatgc taaaaatgtc atcaaagaaa gcaatatcaa
    23641 aatccagaaa gctgggaact tttcaggggt agataagtta gcaggggcgc aattccagat
    23701 caaaaattca gagaatcaat tcgtgaccgg ttttgatgaa aacactggtg tcgctctcta
    23761 tgatcctgct gagtcagcgt tgacattcac aactgatact gaaggatcca tcagtgtcaa
    23821 tggattaata gacggcaatt atactttagt tgaaacaaaa gcaccagatg gttatcaatt
    23881 aaccaatcca caaaaagaaa ctacttttat agtaaaaaac ggaaaattgc aacaaacaac
    23941 cggtatcatc catggcgcag atgaagccaa tcttgggaat ccaaacggtg tagtcaatcg
    24001 ggaaaataca actacggata acacgattac tgtagaaaat gtccaaaact acggtgattt
    24061 ccacttcatc aaacaagatg tgaacacgca agaaaaatta gccgatgcag aattttctat
    24121 tctaagagca aaagatccaa ctgttaaatt aatgaaaaaa atagcaaatc ttgcctcagg
    24181 agaataccca tatgcttggt cagatgaagt cacaggttct gactgggaag aagtgaaatt
    24241 gatttctgat tcagaaggga aattttcaat cgaagggctg aaacaagggg catactgcct
    24301 tcaagaaaca aaagcaccag aaggctacgc attacctaag aatgaagctg cgtacactga
    24361 atttacagta gatgatgatc caacaacttc tgatgaaaca acgatcgata accaacctaa
    24421 aggaatcttg ccttcaactg gtggtatggg gatcatcgta ttcatcttgg taggtactgc
    24481 tttagttgga ggagcagtga tctacttcaa aaaacgccat caagaaacag aagcttaaac
    24541 tattggaaac aaaaatcata cgataaataa acgatagtga ttcaaatggg gagaaaggtt
    24601 gtgacaagtg gtcggtctct tggtattcgc tcaacaaacg gcaaaatagg aggaactatt
    24661 ttgccgtttg ttgagcgaat actcaggtca aggcgctgat ttcacaacct cttcatatac
    24721 atattagaaa ataggtggac atgatgaata aaagcagaat aagaatactg gacatcttca
    24781 tggcaatcat tttagtcgtt gggatcggga tcttttctta tccttttgta gaagattcac
    24841 tgaatgattt tcttgcccag caaatgatca tccattatca aaagcaagca tcgaataaga
    24901 attcagagga aataaaaaaa cagcaggaaa aaatgacaaa gaaaaaccaa cagttggcag
    24961 agcaaaacgt atcaccaggg ataggcagtt tcaaccaagc agttgatgca aaagcattaa
    25021 aagatttacc tagtaatgcc ttttttatgg aacatatgct tggagtcatc gaaatcccaa
    25081 aaatcaatgt cagcttacct atattcgatc agacaacgga aatatttttg caaaaaggaa
    25141 cgtcattatt ggaagaaagt tcttatccga ctggcgggaa aaacacccat gccgttcttt
    25201 ctgggcatcg tggactccca gaagcaaaat tatttacaga tttgcctaag ttgaaaaaag
    25261 gagaccagtt tttcatccag atcaatggaa agacattggc gtatcaagta gaaaaaatcc
    25321 aagtggtctt acctgatgaa gtagattctt tgggtatcca aaaaggcaga gatctcgtga
    25381 ctttgcttac ctgtactcct tatatggtca atacacatcg actgcttgtg acggggcatc
    25441 gtattcctta tcaagcaaaa gaggcaaaaa aagcgatcca aggaattgat caatggaaaa
    25501 aatggaaatt ttttatttgg tttatcggta tactacttgg atcaatcggc ttagtttggc
    25561 tactcatcgc ttatttagat tctttggcca tcgctaagcg aaactatcct ttatcttttt
    25621 atgtaaagaa cacaaacgga cgaccaatcg aaggaatggt cttttctgta aaaacgctca
    25681 acggcaaaca ctatattact agagaaaaag ttccatttgt gaaagcttct gatgaatacg
    25741 gactagtgag attttctgat ttaaaaggca ggaactatcg cttgcaacat gaggagctcc
    25801 tgcttaaaat ccatgtaaaa cataaacatt cgaaacagtt ttcaatgaaa ttgaaaaaag
    25861 gaagatataa actgcgaaaa gaaaaagagg tgtactattt gattgagaaa gaatgaatga
    25921 agatgtccaa aaaagcagag ggaacagact aaatgaaaaa agagagaagc tgacgaaatg
    25981 gacgtgtaaa ctgctatttt tggtttacta tctggaacgc cagcttctat ttttttatgt
    26041 ttcagaagaa ttttattatt atagtataac ttttgaatta gtttccataa catttggagc
    26101 aaggggttaa accacgagct tgagcttcgc ttaaagtggc aggggtatac gtaccatttc
    26161 cacatttatg tgtatggtat tttgaaccgg tcggtgtgac atagacagtt tgttcattat
    26221 tttgctcagg agctgcggct tgtgcctgct gagaggcctg ttcagctgct gcttgctgtc
    26281 gcgcctgttc tgcttgttgc tgtgcgattg cttcttgttg cgcttgttct gcttgttgtc
    26341 gtgcaatttc ttcttgcttt ttccgttctt cttctgcttc ttttgctttg attgtggaat
    26401 caattgcagc aagacggctt gtcaactctt gtttgttttc aggtagcgct tggatagctg
    26461 ctgaagcagt tgcatagttt tcttttgtag gatttgcttc agcttgtgac aaagcagatt
    26521 ccgcttctgt cacttttttt tctagtgcag ctttttccgc tttttgtttc tcttcttctt
    26581 ttttcttttc aatttgttct tgttctttcg atgaatctgc cgtactttcg gagatcgtgg
    26641 tactgctgct ggaagcctga gctgaacttg tgctttgagt agtagacgta gtagcaccac
    26701 acccactcaa caaacttcct gcgaccaaaa acaatgcaac taattttttc actaaatttc
    26761 ctccttaagt aaaaaacaac cgttttcaat aaatgtcctt ttcaattgtt tacttacttg
    26821 ttataataat tgtgttatga atagtgattg aggaaactta atctaatccc gttttgatac
    26881 acgggatttt ttgctatagt tctgttatta agtatgcaat aataaaatat gtacgttatt
    26941 ttattattag attattgaca tttatataat aaacgattaa atgattcata tcaatagaat
    27001 acttaggaaa aaaagagaaa taataacagg tttatgcact attgacggtg tgacaatatg
    27061 atatttgtat ccgttttttt tcttgtatgt agtatagtaa agtagataca ggaggagaaa
    27121 atatgcagac ttttttaaca aaagtttctc aaaagaaaat taaaatgatt catttactgc
    27181 ttgaaacaga acgttggtgt tcaatagaag aactacaaaa cgaattgaag gtatcaagta
    27241 agtctatctt gaattatcta acagatttag aagaattgtt ccaaaaatat cctgataagg
    27301 tcattttgaa gaatgagaat aatcggcgct tttctatgga aaagcaggag aacttcccaa
    27361 tctacattat ttatcttcat ttctacagaa aatcatataa ttatcatttg attgaattca
    27421 tgtatcaaca tcctgagaaa aatttggaag attatgcaga cgctcaatat acgagtgtat
    27481 ccacagtttt tcgttatgct aagttattag taaagtactt tgaaatgacg gacgtcaaag
    27541 aatagtagcc gccagataga aggaaattag cagttgaaaa agctgccctg catcaagtaa
    27601 tacgaccagc caaacggaaa cagtgtctca tgtttttgat ttggctggtc ttattaccgc
    27661 agatgcaagc ttttgccaca cctctttctt gtcatttaca gactcaacta tcaatgctgc
    27721 aagctttccc ttaatgctgt aacaccagta agagttgtca agaccagcag actgactagg
    27781 taaataccgc tcaaaaacaa gattacggca gttaaactat aatgatccat caagaaaccg
    27841 atgacgatag aagaaaaacc accaacagct cgtccaaggt tcataatgaa attattcgcc
    27901 gtcgcgcgga tttctgttgg atacaaacta ctaatcactg cgccatatcc accatacatg
    27961 ccattgataa agtagccgac tatcacagcg gctgctacca aactccactg gctatgggct
    28021 aacacaagta gatagacaga taaggatgaa caaattaaaa acaaagaaaa ggctagttta
    28081 ggccccaatt tatccatgat tatgccaaaa gtcatcatcc ccaaagacat gcctaaaata
    28141 gtactgacca tccacaatga agacccagaa accgaaagcc ctaatcgatt ttgcataatt
    28201 gaaggcagcc aattcattaa cccaaaatag ccggcaattt ggacagttac catgatacta
    28261 aggccacatg tttgccaagc aagatgtttt gattcaaaca gtctgctaag tttggttttc
    28321 ttttcggcag attgtacaga tttgaattcc tttggttcag tcaagccgcg acgaatgaac
    28381 aagaccatca acaccggcag tacacctacg acatacaaca tcttccaacc aaacgttgga
    28441 atgatcacag cagctaaaat cgcagccaaa gccgcaccga cctgcgcacc aataccagca
    28501 accgaagaag ctcgtccaat ttgttttttt gaaaaacttt cggaaatcaa ggacatacac
    28561 gccccgtatt ctcctcccgc tcctacacct gcgataaagc gaaagagata aaccaagtag
    28621 atgtttgaag caaaatacat caataaagaa gcaatcgaaa acagaaggac cgtttgagaa
    28681 aatactttca cacgtccata tttatcagct atgatgccaa aaaaaatacc tccaatgagc
    28741 atccccaaat tagtgatcgt tgaaatgaaa cccgcttgcg taccactaat atgaaaagaa
    28801 gtaatcattg aagataatga aaaagctaaa aacataatat ccatattctc taaagcaatt
    28861 cccgccgatg tcgataataa taactttcgc tgatacgttg tcatttttat accccttttc
    28921 ctaaaatttc cctaaattgt taaaagtata tccaaaaaag aataaaaaaa caagactttt
    28981 ttatttgaaa taatacacaa acaaccgata tagataatcc agcttagttt taatagaaat
    29041 gagtattgac ttggagtaca cttaaagttg tagaataaat aaaatacata agtaaagtgg
    29101 caagaaatta agagaaagag tgatcagatg aatatcaaac aagtcagtga agaaaagggc
    29161 atttcggccg atacattgcg ctattatgaa cgaatcgggt tgattccacc agttaatcgg
    29221 acaaaaggcg gaatccgtga ttatacagaa gaagacctaa aatgggtcga ctttacgatc
    29281 tgtatgcgaa atgccggatt atcgatcgag tctttgattg aatatattcg cctatctagc
    29341 gaaggagaag caactgtatt tgagcggcgt aagcttttga ttgaagaaag tgaacttttg
    29401 acgaaaaaaa ttgctgaaat gcaagaatgt ttggaacgtt tacaaggaaa aatcaagaaa
    29461 tatgatcgtg tgttatctag aaataaaatg gaatgtatca agtaaaaaaa tcaaggagca
    29521 tcgctatgga gttacgctta ctaaaatatt tttggacaat tgcagaagaa ggaacaatct
    29581 ctcaagccgc agaagttcta catcttacac aaccaacctt aagccgacaa ctgaaggagt
    29641 tagaagagga actaggaaca gaactgtttg tacgcgaaaa ccgcaaaatg atcttgacag
    29701 aagcaggtta ttttctaaaa aagccgagca gaagaaattt tagatttaac gaatcaaacc
    29761 actcaagaat tcgagaacag aaaaaaacaa ttattcagcg gccgatttac gatcggctgt
    29821 gtggaagctg ataattcgaa tacattggca ctattactag aaaagttgat ccgtgattat
    29881 cccagcgttc aatttcatat ccacagcgga acaagtgatg atatcacgga gtgactagaa
    29941 aaaagcctgt tagatttagc gattttgcta gatccagtag atacagagaa atacgaaacg
    30001 attttgttac caagaaagga aaaatgggga ttgctcattt tagaaaattc tgttttagca
    30061 aaaaaagacg tgataacaaa agaagacttt gcgaatgtac ctcttttgat ctcaaagcgt
    30121 ccagaaatac agcgaatgtt tgctgactgg ttaggcataa aaaaggagca gttgctgatc
    30181 acaggaacgt acaatttgat tttcaatgta tttgcgctaa ttgagaatca ggtaggtgct
    30241 gctttagtca tagaaggtgc tgtaagtcat ctttcaaagc gagtgacatt cgttccgctt
    30301 gacccaatga ttgaaacgaa ctgcatgcta gtctggaaaa agaatcggat tttatcacct
    30361 gtagtcaatg aattgattca ccgtttcaaa gaagcttttg aacagtaata agtatctcta
    30421 atcgaagaaa tttcaataca aaagcgagac gtatgacagt cttgcttttg tattttttca
    30481 tttttaaatc aaaaaaaata aagagattta cataacttgt taaataagcg cttacaaaca
    30541 taagaagaac ggaaatgaat cagctataat aaccgttgtt ctggattgta atcattacaa
    30601 acaaatgaag attataactt tggaggtgtt cgaaatgaaa gaaaaaaagc aaaaattcgt
    30661 tcaaaaaaca tgccctttat tcaatggttg ggtatgattc tgctgattgt attagcttta
    30721 ttgacgatca ttcctttttt atggatggtt tctgcttcat tcaaagcaaa taatgaagtg
    30781 ttcacgattc cgattcaatg gatccctaaa acttggcatt tagagaatta tctggttatt
    30841 tggtctcgta ttcctttagt gacatttttt aagaatacag cttttttaag cgttgtgatc
    30901 acgttgattc agttgtttac ttctagtttt gctgcttacg ggttttctaa actaaatttt
    30961 aaagggcgcg atattttatt tttagcatat atcggcacga ttgctgtccc ttggcagtct
    31021 tatatgatcc cgcagttcat tatgatgaga aaagtgggtt taacatatac gttgtggtcg
    31081 ttggtgctat tacaagcgtt caatgctttt ggtgtgttct tgttgaagca atactacagt
    31141 agtatcccag attctttatg tgagagtgcg cggatcgatg gcttatcaga gtggggaatc
    31201 tatcgcaaga tcattttacc tcttacaaaa ccggcgattg ccagtttgac gatcatcaca
    31261 ttcgttaata catggaacga ttatatgggg ccattcattt atttgtcttc tacggaaaat
    31321 aaaacaatcc agttagggtt gaaaatgttt attgggctat ttgatgcaga gtacgcatta
    31381 atcatggctg cctcagttgt ttctgttctt cctgttgctt ttatattttt agcgatgcaa
    31441 aaatattttg tagaagggat cgcttcatca ggaatgaagg aataggaggt gattatgaaa
    31501 gagcagcgtt ttgacaaaaa tgtttatatg gaattctttt attggttgta tcaatcattg
    31561 gcaagtagcc tttgtttttg gtgtgtcaat atcttgtata tagcagctgc gttccttttg
    31621 tcgatagatg gaaggaatgt cttttccttt attttttctt tactttttat tggtccaggt
    31681 tgcatcgtga tgataggtat gacagaagaa ttagcaaaag aaaaaagttt ttcaccagta
    31741 cgtttgttca taaagacgtt tcgccaattt tggctaaagg gattttttta ttggctattt
    31801 gcttggatag ttagtgtgat aatgattttt gattgtttct tttttatacg tttttcttat
    31861 ggaaaatggt tgattccgtt gtttgtttta cttgcttgtt tatcagtttc ctttagcatc
    31921 aactactggt attttcaggt gagaaatcca gcgtcgaaac caaatcaagt tctacggata
    31981 gcgttctact atacgttgaa aaaatggtat gtgagtttac tagatttttt actattgaca
    32041 agtttgtttc tcttcttttt cgtaaagccc caatggtgta ttctactagg tccttctatc
    32101 gtatttggtt tgatttactt caacaatcgt aaattgatga gaactatgga tctgtagact
    32161 ttataaattg aaactttcaa ttaagaatga cagtttttat gtaaaaactg tcattctttt
    32221 tcattttttg aaacatatgg ctaaacaaat gaaataaaac gtgctatact tttgaatgaa
    32281 acaggtttag aaactgtatc aattatttgt gattatttct aactaataat taaaaataaa
    32341 gcataaaaag gacgatgttc aatggacgaa aaaatgaaac aaggttcgaa atctgtagta
    32401 gaaagtttga ttaatcatca tgttgattat gtattcggta taccaggtgc aaaaatcgat
    32461 ggtgtattta atgaattaga ggatcaaggt cctgaattaa tcgtgactcg tcacgaacaa
    32521 aatgctgcat ttatggcaca agcaatcgga cgtattacag gagagccagg agtagttatc
    32581 gcaacaagtg gtcctggtgc tagtaactta gctacaggtt tggtaacagc gacagcagaa
    32641 ggtgacccag ttttagcaat tgccggacaa gtaaaacgaa gcgatctatt gaagttgacc
    32701 catcaaagca tggataatgc agcactgttc cagccaatca caaaatacag tgcagaaatc
    32761 caagatccag aaacaatttc agaagtgatt gccaatgctt atcgtatggc taagagttca
    32821 aaaaaaggcg cgagctttat cagtatcccg caagatgtag tggatgcacc tgtccaaggg
    32881 aatgtcatca agccattgag cgatcctaaa ttaggttctg cttctgcaga tgatatccgt
    32941 tacctagctg aacgcattag agaagcaaaa ctaccggtac tattagtagg tatgcgagga
    33001 tcaagtgaaa aagaaacgtt agccatcagg caattagttg gaaagacagc attgcctgtt
    33061 gtagagacat tccaagcagc tggagtgatc tcacgtgaat tagaagcgca tttctttggt
    33121 cgtgtgggtt tatttagaaa ccaaccagga gatatgcttt tgaaacgaag tgatctagtt
    33181 attgctattg gctatgatcc aatcgaatat gaagcaagaa actggaatgc ggaaaaagat
    33241 gcgcggatca ttgtgatcga tgaagcgcca gctgaaatcg atccttttat gcagcctgaa
    33301 agagaattga tcggtgatat ctcagccact cttgatttat tgacaggttc attagagcct
    33361 caacaagtgt cagaagatgc aaaagaatat ttagcatctc ttcaagcaga attaacggag
    33421 cgggacattg ttcaatcaaa aggagaagca ggtatcttgc atcctttaga agttattaac
    33481 acgcttcagt caaaagtaac agatgatatg actgttaccg tagatgtagg tagtcattat
    33541 atttggatgg cacgccactt tagaagttat gaacctcgtc atttgttatt cagtaatggt
    33601 atgcaaacgc ttggtgttgc attgccatgg gcgatttctg ctgcattggt gcgtccaaat
    33661 acacaaatcg tatcagtttc cggcgatggg ggatttttat tctctgccca ggatttagaa
    33721 acggcggtac gtaaaaaatt gaatatcgtt catttgattt ggaatgatgg acactacaat
    33781 atggtagagt tccaagaaaa aatgaaatat cagcgggcgt caggtgtaga ctttggtcca
    33841 gttgattttg tgaaatatgc agaagctttt ggcgctaaag gaatccgagc tacaagtgta
    33901 gaggaattag aaaaagcttt agaagaagga tttgcgacag aaggacccgt aattattgat
    33961 attccgattg attaccgtga taatgagaaa ttgggagaaa caatcttacc agatcaattc
    34021 tattaaggaa gtgtcgacat gactgaaaaa atcttatacc agcacgggac attaggagct
    34081 ttgatggctg gcttgatgga tggaacagaa acgattgctc atatattaga aaaaggaact
    34141 ctgggattgg gaacattgca tgggcttgat ggtgaagtca tctttttaga tggcgtagct
    34201 tatcaaggaa gatcagatgg ctcagttgcc caattagatg gaagtgaact taccccctat
    34261 gcagcaatta cagattttac gccagatact agtttttctg tctcaaaaac tgcagatgga
    34321 gaacaattga aaaaagacat attagtaaga gaagccgggg aaaacctatt tttggcagtg
    34381 aagataactg gattattcaa aaatatgcac atccgtatca tgccgaagca agaaaaacct
    34441 tacagaagac tagcaaaaat ttcagagtct caaccagaat tccaacaaag caatgtccaa
    34501 ggaacattag tcgggttctt tacgcctgaa ttattccaag gagttgctgc agcgggattt
    34561 cacttgcatt ttatcgatga tacacataca tttggcggac atgtaatgga ttttgaagtg
    34621 gctgaaggaa aagttgagat tagccgcatc tcgtcccttg tacagcattt tccagttgat
    34681 gatccgactt ttgttcacga aacgattgat tatgctgatt tagcagcaga aatccaacaa
    34741 gcagaataga aaaagacagc gagatgcgtt caaggtgatt aacctgacgt atctcgtttt
    34801 tttgaggagg aaacctagcg tttacaaaaa aactgagcta taatcttctc catagatcaa
    34861 aaaggagcgg tttttatcat gtggacagaa aaacagaaaa aagatgcata cgaaatttta
    34921 ttattacagc aacaaggatt attagaagca gaagataact ggttagcaaa tttagcaaat
    34981 tcatctgcat tgttgaatga gactttgcct gagactgtct ttgcaggata ttatttattc
    35041 gatggtaatg aattgatttt aggaccgttc caagggcgag tttcttgcac acgtatcaag
    35101 atgggaaaag gagtttgtgg agaatcagct gaaaaacaag aaacattgat cgttgatgat
    35161 gtcaaaaccc atgcaaatta catttcctgc gattcagccg cacaatcaga aatcgtagtg
    35221 ccaatggtaa aagaaggtaa tttaatcggt gttttagata tcgattgcgg agtaacgaaa
    35281 gggtatgatg aaatcgatca agcatttcta gaaaaatatg tagatctttt attagcaaat
    35341 tttaatataa atgctttttc atttattaat aactaaaatc gtctattgaa acaaaaaaga
    35401 agagaaatca agaataaaaa gagccggaaa gacagtgggc atttctgttt ttcggttttt
    35461 ttattttttt ataaaatcac aagtgttatt gattttcata atcatatttt aatggtatta
    35521 tcattttaaa taatggaaaa acattaagga tggatgaaat atgaataacg aaactatcat
    35581 tttaggaaaa aaatatattt gccaacctat tggcttgaaa caaaaagtgg ttggagaagt
    35641 aatcagtaaa ttagaaaatt gtgttgtgat ctgcgtagac gaatatcatg acgtcgatcg
    35701 caatgaaata ttagaaaaat gcggaaaagt agtggcaaaa tatactcacg tttatgagtt
    35761 ggaaacaaca gaatatctat ataactatag caacaaatat gaacatactt tagtttcata
    35821 aagatttaaa taaagtgcct tcaaaagcga gaagaccaag cttttgaagg cactttattt
    35881 agttggcagt gattgttcat gatttttgat ttattcaaaa ggttcgccta gagaatctgt
    35941 ctctgtaacg aggcctggtg gagaaactcg ataaaaacct atactgccag aactgtccta
    36001 ttttcggata gacaaactag tagttttaaa aagatcatcc gatccaatca tttcaaaaaa
    36061 tgcaaaactg atatcaggat catttagctc aggcttgtta tcgtaaagca tttgtaaagg
    36121 ttgcatttag ttaggagtaa acgcgaaact atcatcatta tttgctgaag aagatgaaga
    36181 agctaattca gagtttgttt gaaataaagg agacgtgctg acagtttctt taccctgttt
    36241 tttgcagagg tagaaacttt tatatcggaa gtttctaccg gagaattttt ctcatttgta
    36301 gaaattgttg aatcgatact attcgaaatt tgcgtatctg aaggtatgtt ctttgatgca
    36361 gaagtcccac aagcagtaag taacaataaa tttgataaac tgataaacag aattcttttc
    36421 attatgtaca cactccttat agtatcgttt agcatacacc tatgctcagt attaggcaaa
    36481 atcaatgcaa aactatcaag tcttttatag tatctattag tcttagtaat acatatatgg
    36541 agagggtgat atcccagttc aaaccagata cattggttac catctgtatt aacgattatg
    36601 cctctaaacg ctttttttat gaaaaaattt ataagtgaaa acgtaggtat gatattatct
    36661 agaggtaatt tttttgggta tttaaatagt tgctaggagg ata
//
LOCUS       DAIGQM010000022        36567 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.022, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000022 DAIGQM010000000
VERSION     DAIGQM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.022"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOA48_001102"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOA48_001102"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCI0789379.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOA48_001103"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOA48_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCI0789380.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOA48_001104"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOA48_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCI0789381.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOA48_001105"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOA48_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCI0789382.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOA48_001106"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOA48_001106"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCI0789383.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOA48_001107"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOA48_001107"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCI0789384.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="NOA48_001108"
     CDS             complement(8052..8522)
                     /locus_tag="NOA48_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCI0789385.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="NOA48_001109"
     CDS             complement(8568..8993)
                     /locus_tag="NOA48_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCI0789386.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="NOA48_001110"
     CDS             complement(9060..9329)
                     /locus_tag="NOA48_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCI0789387.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="NOA48_001111"
     CDS             complement(9340..10935)
                     /locus_tag="NOA48_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0789388.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOA48_001112"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOA48_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCI0789389.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="NOA48_001113"
     CDS             complement(14488..15048)
                     /locus_tag="NOA48_001113"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCI0789390.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="NOA48_001114"
     CDS             15401..16375
                     /locus_tag="NOA48_001114"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0789391.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="NOA48_001115"
     CDS             16545..17945
                     /locus_tag="NOA48_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCI0789392.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="NOA48_001116"
     CDS             complement(18023..18745)
                     /locus_tag="NOA48_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0789393.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="NOA48_001117"
     CDS             complement(18824..19330)
                     /locus_tag="NOA48_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0789394.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="NOA48_001118"
     CDS             19453..21252
                     /locus_tag="NOA48_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCI0789395.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="NOA48_001119"
     CDS             complement(21320..22894)
                     /locus_tag="NOA48_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0789396.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOA48_001120"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOA48_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCI0789397.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOA48_001121"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOA48_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCI0789398.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="NOA48_001122"
     CDS             complement(24671..25309)
                     /locus_tag="NOA48_001122"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCI0789399.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="NOA48_001123"
     CDS             complement(25310..25960)
                     /locus_tag="NOA48_001123"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCI0789400.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOA48_001124"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOA48_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCI0789401.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOA48_001125"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOA48_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCI0789402.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSREESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="NOA48_001126"
     CDS             complement(29103..29843)
                     /locus_tag="NOA48_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCI0789403.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOA48_001127"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOA48_001127"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCI0789404.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="NOA48_001128"
     CDS             complement(31214..32152)
                     /locus_tag="NOA48_001128"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCI0789405.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOA48_001129"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOA48_001129"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0789406.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOA48_001130"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOA48_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCI0789407.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="NOA48_001131"
     CDS             complement(35312..35617)
                     /locus_tag="NOA48_001131"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0789408.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOA48_001132"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOA48_001132"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCI0789409.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7990 c         6705 g        11987 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc ctactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgctt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttctcttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaata
//
LOCUS       DAIGQM010000023        36538 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.023, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000023 DAIGQM010000000
VERSION     DAIGQM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.023"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..180)
                     /locus_tag="NOA48_001133"
     CDS             complement(<1..180)
                     /locus_tag="NOA48_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0789410.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYY"
     gene            384..1034
                     /locus_tag="NOA48_001134"
     CDS             384..1034
                     /locus_tag="NOA48_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0789411.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            1050..2777
                     /locus_tag="NOA48_001135"
     CDS             1050..2777
                     /locus_tag="NOA48_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789412.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            2774..4666
                     /locus_tag="NOA48_001136"
     CDS             2774..4666
                     /locus_tag="NOA48_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789413.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            5370..6239
                     /locus_tag="NOA48_001137"
     CDS             5370..6239
                     /locus_tag="NOA48_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCI0789414.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            6448..7473
                     /locus_tag="NOA48_001138"
     CDS             6448..7473
                     /locus_tag="NOA48_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0789415.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            7512..8462
                     /gene="manA"
                     /locus_tag="NOA48_001139"
     CDS             7512..8462
                     /gene="manA"
                     /locus_tag="NOA48_001139"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCI0789416.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            8556..10259
                     /locus_tag="NOA48_001140"
     CDS             8556..10259
                     /locus_tag="NOA48_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0789417.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            10261..12294
                     /locus_tag="NOA48_001141"
     CDS             10261..12294
                     /locus_tag="NOA48_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0789418.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            12305..12745
                     /locus_tag="NOA48_001142"
     CDS             12305..12745
                     /locus_tag="NOA48_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0789419.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(12945..14072)
                     /locus_tag="NOA48_001143"
     CDS             complement(12945..14072)
                     /locus_tag="NOA48_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789420.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(14075..14752)
                     /locus_tag="NOA48_001144"
     CDS             complement(14075..14752)
                     /locus_tag="NOA48_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789421.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            15016..16782
                     /locus_tag="NOA48_001145"
     CDS             15016..16782
                     /locus_tag="NOA48_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCI0789422.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            16797..17234
                     /locus_tag="NOA48_001146"
     CDS             16797..17234
                     /locus_tag="NOA48_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0789423.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            17247..18398
                     /locus_tag="NOA48_001147"
     CDS             17247..18398
                     /locus_tag="NOA48_001147"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCI0789424.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(18460..19158)
                     /locus_tag="NOA48_001148"
     CDS             complement(18460..19158)
                     /locus_tag="NOA48_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCI0789425.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(19151..20503)
                     /locus_tag="NOA48_001149"
     CDS             complement(19151..20503)
                     /locus_tag="NOA48_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCI0789426.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(20726..22126)
                     /locus_tag="NOA48_001150"
     CDS             complement(20726..22126)
                     /locus_tag="NOA48_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCI0789427.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            22317..23024
                     /locus_tag="NOA48_001151"
     CDS             22317..23024
                     /locus_tag="NOA48_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCI0789428.1"
                     /translation="MKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCCAPCSTHTLEF
                     MSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIVDEYRPNEFTK
                     MVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISPKKNAALINQI
                     GMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAKQQGCDLKEIN
                     REAKAYLKTSTVVFEEN"
     gene            23149..23628
                     /locus_tag="NOA48_001152"
     CDS             23149..23628
                     /locus_tag="NOA48_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCI0789429.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            23625..24392
                     /locus_tag="NOA48_001153"
     CDS             23625..24392
                     /locus_tag="NOA48_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789430.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            24622..25191
                     /gene="lepB"
                     /locus_tag="NOA48_001154"
     CDS             24622..25191
                     /gene="lepB"
                     /locus_tag="NOA48_001154"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0789431.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(25295..25897)
                     /locus_tag="NOA48_001155"
     CDS             complement(25295..25897)
                     /locus_tag="NOA48_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0789432.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26003..26472
                     /locus_tag="NOA48_001156"
                     /pseudo
     CDS             26003..26472
                     /locus_tag="NOA48_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            26578..27162
                     /locus_tag="NOA48_001157"
     CDS             26578..27162
                     /locus_tag="NOA48_001157"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCI0789433.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            27165..28238
                     /gene="prfA"
                     /locus_tag="NOA48_001158"
     CDS             27165..28238
                     /gene="prfA"
                     /locus_tag="NOA48_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCI0789434.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            28231..29070
                     /gene="prmC"
                     /locus_tag="NOA48_001159"
     CDS             28231..29070
                     /gene="prmC"
                     /locus_tag="NOA48_001159"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCI0789435.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            29063..29242
                     /locus_tag="NOA48_001160"
     CDS             29063..29242
                     /locus_tag="NOA48_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789436.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            29264..30289
                     /locus_tag="NOA48_001161"
     CDS             29264..30289
                     /locus_tag="NOA48_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCI0789437.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            30464..31708
                     /locus_tag="NOA48_001162"
     CDS             30464..31708
                     /locus_tag="NOA48_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCI0789438.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            31861..32808
                     /locus_tag="NOA48_001163"
     CDS             31861..32808
                     /locus_tag="NOA48_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0789439.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            32942..33571
                     /gene="upp"
                     /locus_tag="NOA48_001164"
     CDS             32942..33571
                     /gene="upp"
                     /locus_tag="NOA48_001164"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCI0789440.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(33710..33952)
                     /locus_tag="NOA48_001165"
     CDS             complement(33710..33952)
                     /locus_tag="NOA48_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789441.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            34073..34145
                     /locus_tag="NOA48_001166"
     tRNA            34073..34145
                     /locus_tag="NOA48_001166"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34106..34108,aa:Thr,seq:cgt)
     gene            complement(34264..34902)
                     /locus_tag="NOA48_001167"
     CDS             complement(34264..34902)
                     /locus_tag="NOA48_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0789442.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(35025..35657)
                     /locus_tag="NOA48_001168"
     CDS             complement(35025..35657)
                     /locus_tag="NOA48_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0789443.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            36008..36307
                     /locus_tag="NOA48_001169"
     CDS             36008..36307
                     /locus_tag="NOA48_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0789444.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12368 a         6405 c         7388 g        10377 t
ORIGIN      
        1 ataataaagt ttctttggat ctagattttt taattgtctt ggcaagatag cagcggggat
       61 agaaagcgag tggcttaagt ggttttttgt gtaatctaag gtatttcttg tatctaaaac
      121 gatgctgtca gcatcgagag gcaatttatt gaagtcttgg acactaattg attgggccat
      181 ttatctcatc ctttgtttag tatgtggcta ttttaatggg caactctcat taattcaaat
      241 ggaaggattc ctcttatcac ttttttaatg tatcggatga taatgaaaaa aactatgcaa
      301 atgtcttgca aaacaggtag gaggtgttat aatgacatag cgtcatatga caatgtgtca
      361 tcttgaaaga aaggagaatc catatgccga cacagacatt tttccatttg cctaaagaaa
      421 aacaaaaaag actaatcgag gctgcgagaa tcgagttttc tagagtaccc ttaaaagaag
      481 cttcgattgc taatatcgtc aaattagcgg atatccctag aggcagtttc tatcagtatt
      541 ttgaagataa agaggatctt tatttttatt actttgagac aatgagacgt gacagctcta
      601 aagatatgtt acaactaatg aaagaatccg atggtgatct attcaaagga ttcgaatcct
      661 atttttctaa aatgatttat gagattttgg aaggcgagaa tgcttctttt tatcgtaact
      721 tgtttatgaa catggattac cgtgcctcaa gaaaagtcgc tcctcatacg agtcgccaaa
      781 aaacgcctca cgatccacat aaagaacaca aacaagatgc aaaagagttg cttgaattga
      841 tcgatcggac gaagctgaaa gtaaaaaatg atcatgaatt ggaattactg atccaattag
      901 tgatgaatac tgtatttaca acaattgcgc attcgtatcg cttattttca acatctgaag
      961 attactcagt agagcaagca atcagtgaat tcaatttgaa actttcttgg ctgaaaaacg
     1021 gagtatataa atagaaagaa gggaactaga tgctaaaaat cgtaaaacgg atctccttga
     1081 cttcagcaat tgcagctgca gttttcatgg tgatccaagt actggcagat ttatatttgc
     1141 cgacacttac ctccaatatt attgataaag gggtagcgca aggagatgtc gattatattt
     1201 ggcatacagg ttttgtgatg atcggctttt ctttgatcag tatcttagct gctatcgcaa
     1261 atacattttt tgctactcgt gaatcacaga aactgggtaa gcaattgcgt acggatgtct
     1321 ataaaaaatc agagagtctg acaaaagatg cgtttgataa atatggaacg gcctctttga
     1381 tcacaagaac gaccaatgat gtgactcaaa tccaaatggt tacacaaatg tttttacgta
     1441 tgatgatcaa tgcaccaatc acgttgattg gcgcgagcat acttgcttat caaaaagatc
     1501 atcagttgac aaaaatcttc ttagttgtca tcccagtaat gattattttg atcggcggaa
     1561 tcatgtactt tgctgttcca ttattcaaaa gtatgcaaaa gaaaactgac cgtttaaacc
     1621 tggtatttcg agaaggattg acaggggtca gagtgattcg agcattcgat aagacacgct
     1681 ttgaagaaaa tcgttttgat ttagcgaata aagattatac aaatacggca atcaaagtta
     1741 atacgatcgt cgcattgatg atgccaatga tgacattgat catgagcggt acaaacgtag
     1801 caatcacttg gtttggtgga cactacatag cagatatgac tttggaagtc ggtaatctga
     1861 ttgcatttat gacttatgcg atgcagatct tgatcagctt tatgatgctt tccgctattt
     1921 ttatcatggt gcctcgtgca caagcttcag ctgaccgtat taatgaagtg ttggatgaaa
     1981 aaatcggtat ccatgaccct gaaaatccta aaacagtttc ttttgctgga aaaaacgcaa
     2041 cattggcctt caatcatgtc aattatcgat atcatggagc agaaaaactt gcattggaag
     2101 atattgattt ccaagccaag tcgggcgaga tcgtcgcaat catagggggg actggttcag
     2161 gtaaaacgac cttagtcaat ttgatccctc gattatatga catcgaatct ggttcgatcc
     2221 aaataaatgg aacggacatt agtgacatga ctcaatataa tttgcgagaa ttaatgggct
     2281 ttgttcctca aaaagcagtt ctgttctctg gaacgatccg agacaatatg cagtatggta
     2341 agccggatgc aacagatgaa atgatttgga aagcattaga aatcgcacaa gctaaagatt
     2401 ttgtttcaga gatggaagat ggcttagata gccatgtgga acaaggagga ggaaacttct
     2461 ctggtggaca aagacagcgt ctggcaattg cacgggcatt agtcaaaaca gcagatatct
     2521 atgtgtttga tgattccttc tcagcgttgg atttcaaaac ggatgccaat cttcgccaag
     2581 cattgaaaac gaatatgaaa gaaagtatca ccgttttagt tgctcaacga gtaagtacag
     2641 taatggatgc agatatgatc cttgtgctag atgaaggaaa actggttggc aaaggaacac
     2701 atgaagaact attagcaaca aacgaaactt atcaagaaat cgttcattca caactaagag
     2761 aggaggactt agcatgagta aaacaaacac acgtccctct catggaccag caggcggtcc
     2821 aggacatggt ggacctggca gaaatctcgg tgtaaaaggt gaaaagccta aaaatttctg
     2881 gggaacggta cgccgattgt ttggctatat gtctaaacgt atggttgcga tcatcgctgt
     2941 atttgtacta gcaatagcag ccgtgatctt ccaaatccaa acaccaaagg tcttggggaa
     3001 agcaaccaca gaaatattca aaggtgtaat ggctggcgct caacagatgc aacaaggcca
     3061 acaagtaaca aaatttccga tagactttga taaaatcgcg cagatcattg cgacagtaat
     3121 cgtgatgtat ttgatttctg ctgtattcaa ctttttacag caatttatta tgacacgtgt
     3181 ttcccaacga acagtttatg aattacgtca tgatttggaa gccaaaatga atcgtgtacc
     3241 gatttcctat tatgatacac atacaaatgg ggatatcatg tctcgagcaa tcaatgatat
     3301 ggataacatc gcaagcacgc tgcagcaaaa tttgactcaa tttgtaacta gtgcagtcac
     3361 attgattggg gtcatcgtga tgatgctttc aatcagctgg caattgacgt tagtcgcgtt
     3421 attgatgatc cctttaagct tgatcatcgt gatgatcgta gcgccgaaat cacaagtgtt
     3481 tttcgcagat cagcaaaaaa gtttaggttt attgaataac caagtagaag aaacatatgg
     3541 tggtcatacc attgttaaaa cattcaatca tactgaaaaa gaccaggaag tatttgaaaa
     3601 agaaaatcag aatctgtatg ccgctggttg gaaagctcaa tttatttcgg caatcatcat
     3661 gccgttgatg aatttcgtta aaaatctagg ctatgtgttc gtcgctgtac taggcggagt
     3721 aaaagttgca aatgggaaca tgacattagg ggatgttcaa gcgttcttgc aatatacaac
     3781 acagttctct caaccaatca ctcaacttgc aagtttgatg aacactatcc aatcaacagt
     3841 tgcttcagcc gaacgggtat ttgaagtgtt ggatgaagaa gagatgtcca atgaaaaatc
     3901 tggccttcca gaagaaaaag atacaccata caaagttcgt tttgaaaatg ttcaattcgg
     3961 ctacacacca gataacttgc taatgactga ttttaacttg gatgtcaaac ctggtgagat
     4021 ggtcgctatt gtaggtccga ctggtgcagg gaagacgaca ctgatcaacc ttcttgaacg
     4081 gttctacgat gtttctggag gtagtattcg ttacgatggt gtagataccc gtgatctttc
     4141 acgtgatgaa ttgcgcgcac agttttcaat ggtactgcaa gatacttggc tgtttacagg
     4201 aagtatctat gacaatatca aatatgggaa cgacgatgca acagacgaac aaatcattga
     4261 ggctgctaaa gctgctcacg tagacgattt tgttcgtaaa ttgccagaag gatataacac
     4321 tgtattaaac gaggatgcaa gcaatatttc gcaagggcag cgtcagctaa tcacaattgc
     4381 gcgggcattc ttagcaaatc cagatgtcct gatccttgat gaagcaacat ctagtgtaga
     4441 tacacgaaca gaaatactga ttcaaaaagc gatgaaccgc ctattggaaa accggacaag
     4501 tttcgttgtt gctcaccgct tgtctacaat acgcgatgca gacaacatta ttgtgatgaa
     4561 tcatggttcg atcgtagaaa caggaaacca cgatacattg atggaaaaag acggattcta
     4621 tgcagatctt tataacagtc agttttctga agaagaagct tcatagaata gtacaaattt
     4681 attatttttt ttaggggctg tgacaaaagt cgtgtcacag tccctttttc cgaataaacg
     4741 gtgttcaatc agctgtcctt cggtattagc tcaaaaaacg gcaaaatatg agaagctatt
     4801 tttccgtttt gtatctctaa tactcaggtc aaaccgctga ttttacaacc tcttccttaa
     4861 acggtgttct cctgccaact cctcggtcac aagtcacaat agtcaacaaa cctgagaagc
     4921 tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcaca acctcttggt
     4981 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa
     5041 gccattttca caaaattttt cttactactc gaaactaagc gactttttca caacctcttc
     5101 cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatagg
     5161 aggagctatt tttgtttggc tgttcttatt acttgatgca gaacagcttt ttcacaacct
     5221 ctttttataa gagtttttac tcattaattt acaaaaaaca agcaaaatgc gaattttctc
     5281 acattttttt taacaaaatc aaagttattg cttgaaagaa gaagaatcca tcgttaaaat
     5341 aaagcttgac gtagagggga gcaagaaata tgaaagattt tcaattgggg gctgccacct
     5401 atttaaaaag tgtagccatt cgggtgaaag accgagataa aatgattgat ttttacaaga
     5461 acgttgttgg ctttgatttg aaaagagaag aaaacgaatt agccatttta ggaacagaag
     5521 aagctggaag tgaaatgttg ctgctggaag aaagtcctag agcgaatgat cacatggggg
     5581 tgatcaaaaa gctgaaccgt ttttcattga ttatccctag cacagaagaa atggcagata
     5641 tcctttgtcg tatccgtaaa atgaattatc caatcaaaga agctttagaa gatcatggac
     5701 gtatggggat tttgctcgta gacccagaag agaatgaatt ggaaatttac catgaagaga
     5761 ataagaacga ccaaagagaa attccagaaa caatggatca agaagcatta ttaagaaaat
     5821 ctgaagaaaa attcagtaaa ctatcaacag gttcttattt tgaaaaaatc catttaaatg
     5881 ttactaactt aacaaaagaa cgccaatttc ttaatcatgt acttggtttg aaggtacata
     5941 atgaagaaga gggcatccat gtattgaatg aaggagattt ccatgttggt ttgacagaag
     6001 ctagcggagg cgcaattgat ttgcctacag atgaagtgat tggacttgat tttctgaaat
     6061 tcatgatcga tactgaaagc atggaaggac tgattgctca cttgcagcaa ctatcagttg
     6121 atttcttctt agacaaaaag cacacagtac tcacaatcta tgatgctata ggaatcgaat
     6181 ggtggttcgt cagtgagcca aaagaaaaga ataaaactga cattcgatgc gacgcttaac
     6241 tttttctttc ttaacgattg tcgcatgtct cgtcatttta tgaacggtca tactatcgct
     6301 tattctagag atagaaagag aaaatagtat accgggggaa actgcgcggt ttttcgcgca
     6361 gtttttttgt gtaaaaaagg ttgattcctc atagattaag ctttaagctt ggactgtaag
     6421 aatctgatag aaaagcagga gaaaaagatg tatccacaca cgaaacagct tattttgaaa
     6481 aagatggaag aaggatttta tccaggtgta gcagtcgcct tcataaaaga aaatcaagta
     6541 gaaacattta cagccggctt tgcccaagtc gttcctgaaa agcagctgat gacagaagat
     6601 ctgttgtttg atgcagcctc actgacgaaa gtcgttgcaa ccacttcatt agttttacgt
     6661 ctattagaag atggaaagat agaactcgat caaccgcttc ataaatatct tcctgaattt
     6721 gaaaatcaga caatcacttt gcgtcattta ctgacacata cttctgatat caaaacatgg
     6781 ataccaaaca gagataagct atctcaggaa gaattgatcg ccgcttattt gaagctagaa
     6841 ccaggtgagc aactaggaaa agaagtaaaa tatacagatg ccggtacgat tcttcttggg
     6901 ttgatgctag aggaaattta ccaagaaact gcagtggaaa tctttcaaga acaagtattg
     6961 gaaccattag gaatgatgaa cagcttattt cttccttttc cttccaaaaa aatcgttccc
     7021 acagaacaac tgccttcggg tgaggttttg cgtggacaaa ctcatgatcc gaaagcaaga
     7081 gttttggctg aacatgcagg taacgcgggt ctctttattg atttgaaaga cagcattact
     7141 tttgtccaaa tgtatttgaa caagggaaaa atccgtaatg gtcgtttttt agaagaagag
     7201 acgattgatt ctttactgca agatcaaaca ccgaaaaaaa atggctatcg ttctttagga
     7261 tgggacttaa aaaaggatgt agaagacggt catgcgattc tttttcatac tggttataca
     7321 ggtacgtttt tcttgattga tataaaaaca caagaagcgt tgatattttt gtcaaatcgc
     7381 gtacatcctg tcgatcatcg tgcggagtat ctcatatgtc gagatgaaat tgttgaaaac
     7441 tttttgaaag agaaagcggt attaccgaaa taatgctata atagctatga aaaatgagag
     7501 gagtttgaat tatgcaggaa cctatgtttt taaaaccagt ttttcaagaa aaaatttggg
     7561 gaggaagtcg tttacgttca gtctttggtt ttgatatccc taacgataaa atcggagaag
     7621 attgggcgat cagtgcgcat cctcatggtg tcagtgtagt agaaaatggc gaattcaaag
     7681 ggaaaagatt agatgaacta tggtcagaac acaaggaatt gtttggccat ccttcagaac
     7741 cagtgtttcc attattgatc aagatcttag acgcagaaga tgatctatct gtacaagtac
     7801 atccagatga tgcctatggg atgaaacatg aaggtgaatt aggaaaaact gaatgctggt
     7861 atatcatcga tgctgaacct ggtgcagaaa tcatctatgg tcatcatgca aagacaagag
     7921 aagaactagc tgagatgatc aaagatgggc gctgggatga ccttttgaag aaagtaccag
     7981 ttaaaaaagg tgatttcttt tatgtaccaa gcggaacgat ccatgctatt ggtaaaggaa
     8041 tcatgatttt agaaacacag caaagttctg acacgactta ccgcgtgtat gactacgaca
     8101 gaaaagatgc gcaaggacaa acaagagagc tgcatatcca acaatcgatc gatgtaacaa
     8161 ctgtccctgc gaaaacacca gaattacaaa tcaaagaagt ccgaaaaggg aattcatcga
     8221 tcgtcactta tttagaaact gagtttttca atgtatatga gtgggatatt aaaggaatca
     8281 catctttcaa aaaacaagcc ccttatacat tgatgacggt aatcgaagga gcaggagacc
     8341 ttgtcgttga cggaaaaaca tatccattag aaaaaggaac aagctgtatt attccaaatg
     8401 gcgtttctga gtgggcggtc caaggtgaac tagcaatcat tgcgtctgaa ccaggcaaat
     8461 agttcccaga tagctgaaag cagcagacgg tttttcgttt gctgcttttt ctacataaaa
     8521 tccgtccatc aataaataga agtctggtga aaaagatgga atacaaatgg aaagcaaaca
     8581 acagcagtcg cgtgtctatg aaacaactga gaaaagctgg acatcactta aatgaaatga
     8641 tcatgccaaa tctaagtctg tttatcgctt ggggaatctt gtcattagca acaaaaggtg
     8701 tgtctggcga tttgcatacc acattagaag aggtatgcca ttggatgatc cagctgcttt
     8761 tacccatctt gatcagttat tcaggcggga aatcggtagg gggacaaaaa ggggcagtcg
     8821 ccggtgcaat tgcttcttta gggttgatcg ctcgttccaa tgctccacaa atcgtaggag
     8881 cgatgattat cgggccgctt gccggcatcg tatatgaaca atttgtttct agattccatg
     8941 tgaaattcaa ggctggatat gaaatgcttg tcagcaacct actagtagga ctgactggta
     9001 gcgttatttg tataattgga atcgttttta ttgaaccagt tttaaatagt gttcacttgt
     9061 tgctcgcctc cgttgtgtct tggctagtca caatgaatct gttaccactt gtcagtctga
     9121 tcttagaacc tctaaaagta ctatttttca ataatgcaat caatcatggt gtattgacac
     9181 ctttaggaat cgaattctca caaacagtcg ggtactcttc cttatttttg atggaggcaa
     9241 atcctggacc tggtttaggg atcttacttt ctatcctttg ttttgcagaa aaacaggaaa
     9301 aagtaaatgc gagtggagca ttgatgatcc atgcgattgg cgggattcac gaaatctatt
     9361 ttccatttgt cttgctgcga ccgtatctat ttttagctgt aatggctggt ggggcaagcg
     9421 gcacgttgat atttcaatgg ttagatacgg gattagctgc acctgtatcg cctgggtcac
     9481 tactcgtgat ttttgccaat gcgccttatc cacaactagc tggggtaagt atagggatag
     9541 caatcagtac atttgtgacc ttcatttgtg cagcgatact attgaaatta ccaaataaag
     9601 aaaaagagaa caaaacggtc aaagaaaggg gagaaatctt ggaaccatct atcattcatt
     9661 ccgtcatttt tgcttgcgac tcaggtatgg gatcaagtgc tatgggagcc gccctgctga
     9721 aaaagaaatt agcagcagaa aaaatcgatc tttctgtcgg atacagctct atctatgaat
     9781 tgaataacca agtaaatcag ctggttatcg tgcaacatga actagcgggt cttgcaagag
     9841 aaaaagtacc tcaaagtcaa atctatgtac tggatcactt tttggaaaca gatatcttgc
     9901 tgtcacgaat aaaagaagcg atccaatttc caaagcggga agaaaaaaaa gagatagcag
     9961 atatcacaga acaaaaaacg tcgcctgcta atattgtatt tttgtataaa aacaacagac
    10021 gcggctcaca aactatgggc atgacgattt taagtcaatt agcaaaaaaa gcgaaaaaac
    10081 agtttgttat ctcaaaagaa tcaatagaaa aaatcaaaat ccaagaagaa acgatttata
    10141 tcgcacaaag agaactagct gtaactgaac agctagaaga aaagatccct cggctagttc
    10201 tagttgaaca ttgggtagct acgaatgaat acgaaaaact cgtgaaggga gaaatataag
    10261 atgtatttat cgcccagaga aaaacaatta ttagcagaat ttctcagtag cccgtcacct
    10321 gtatctatcc aaaaaatgat gaatttattg aaggtcagta aacggactat ttaccgcgaa
    10381 ttagataatc ttgaagtctc attgaaatcg gtaaatgctt ctttgaaaaa agcagctaga
    10441 ggctcatttg tcattgaggc atcagaagaa gtattagagc aattaaaaga aaatacagat
    10501 gggaaaagta atgacttatc cactgctaaa cgacaacacg cgattttagc cgagttgtta
    10561 ctgacgacag agccgttgag tcttgctcat ttcatggaat catatcgcat cagtaatacc
    10621 actttttatg cagatatcaa acagttggaa gaaagtattc gccaactgcc tttggaaatc
    10681 attcggaacc agggatacga gatcgaagga ccggaaaaat accgccggct tctgacagcg
    10741 aatgtattag aattagaaat caatgaatat gaactttttc atagtatttc tttcgatgca
    10801 tcactgaatt atttttttcg attcgttgat ccgcaacatc tatctcttgc acgcaaagta
    10861 atcggggaag aattgatcca aaaaaagacc aatctaagtg atagaaagct tgaacatttg
    10921 gttttgatgc tgacattgac gatggagcgt gtgacgaaaa atcatttact gacaaatgag
    10981 acatataata gtctggcaaa caaagaatta ctacagacag ctaaacgatt gttttcacgg
    11041 atcgcttctg agacaaaaca actttatcca gtaaatgaga tcgtcttttt tgcaggatta
    11101 ttaaatgact tcacgaactc atttgatcag aatttctttg aagagacgtt cgatacacag
    11161 cttgcttatt tagtaaaaca actgattcaa gaagtaagtg aagagacgaa tgtccatttt
    11221 tatgaagatg aaactttgta caaaatgctg ttgactcatt tatctggtgt gttttcaaga
    11281 gccgttttac aagaagagac actgaccaat ccgattttag aaaaaatcat ggttcaatac
    11341 gaggaagttg cgaatgcaat ccgtaaagca gtagagcgga tttttcaaga aaaaaaatta
    11401 tccgaagaag agatcgctta tatggtcctt cattttgcga attcattgga acgaagtccg
    11461 aaagaaagca atatcagtat tgcaggattt tcgccaagtg gattagcttc tactagcatg
    11521 ttggaactac gattgaaaag gtattttccc ttcatccaac aaattcattt ctatcggatt
    11581 gctgatttaa aaaaaatcga tttacaagaa gaatatgatg ttgttatttc tacatctatt
    11641 ttaccaggat acggtggaaa atatatttta gtctccccgc tactgctaga agatgaagtc
    11701 aagcagctaa aagaagcttt ttcgcatatt gagaagaaaa aaaggcaaaa aattacgtat
    11761 aacagcaata acgagtggat gatagaagat acttatgagg aaacaatgca tttcatggat
    11821 caaatcaatc aattactcgg tcgttttttt atccaagaac tggataatcc tgagacgatt
    11881 tccgaaacga ttcgcagctt atttccttat tttcctgaag gactagtaac ggatgaagag
    11941 gtggttcatc gccggctgct taagcgatat gaacaagcac ctatcggtat tcctcataca
    12001 aatatggggt tattccatac atccagctca ttgatttcta aaccgatctt ttgtattttc
    12061 aatttgaaac atccgttgac cattgaaggg atggatagac agccagtcga tttgtcccgt
    12121 atgttagtta tgctggcgcc ttcgccaatc caagaaaaag acgggattct tttaggaaag
    12181 atcagtggag caatcatcat gaatgacttg aacaccgaga tcttccgctc aggaaataaa
    12241 gaaatcgttt atcagttgtt agcgaaaatc ctgattgaag aaataaagaa atgaaggtga
    12301 aaagatgata cagctaccag cagaaaaaat attgctcgat caatcctatc aaaattggaa
    12361 agaagcgttg accgagatcg gccagtggat gacccaacaa gggggaatca aaccggcata
    12421 tatccaatca atgatcgaaa gacaagaaaa agcgagtgtc tatatcggga atttcgtagc
    12481 cttgccacat gggactgaca aagatgaaga agtagtagaa gaaggaatct atttagtcca
    12541 agtgcctgat ggtgtggact ttggaacaaa agaggaacca aaaatcgcga cactcttatt
    12601 tgtagtggct ttaaaaaaag aacatcagtt agcggtgctc caagatttag cctttttctg
    12661 ttcagacatc gaccaagtaa tggcgctcag tgatgcggaa accattgaag aagtccaaat
    12721 gatttttgaa catggacata tataaccaat gttcacagta aaaaaagctg ccttgcatca
    12781 agtaataact tcaaccaaga taaaaataag aggagctatt tttgttggga ggttcttatt
    12841 actgcggatg caagcttttg aaaactattt attctagaaa accgtttatt tgaaataggg
    12901 gacggtgaca aggtttttgt caccgcccct attatttttg tgttttaata gctctttttt
    12961 atatagatag tgcccatacc tatgaataat aaaacgatac tccatatacc aagtgtcaag
    13021 ataccattca tgaaagtaac ctgttctgaa gctagtggcg agaaaatatc tcctcctatg
    13081 atcacatttt gaaaatcaac ataagaagtt ggcaagtaat gactgattga ttctatccat
    13141 ccaatcgaag aaaacaagcg atactctgct aagaaaagac aaagaagtgt acctaaaaga
    13201 ttgactagag aatgttcaaa taaagcagat agaagaaaac tgattgtact taaaaagagc
    13261 acccacaaca acaggaacag aaagctctgg aaaagatact catacatcgg caggattcgt
    13321 atctcctgac caatgatcgt tcctacagga taacggaagt ctcccaaacc atttttgatt
    13381 attactagta tagagacgat caaaaatggc atcacgagac ttagcatagc tgcaccataa
    13441 taaatggtaa aacggatgct atgtttcttt accatactat ccggtaatag attgactaga
    13501 gagattacct gctttctttt ttcataagag atgatggaag aaagaaacaa ggcggttata
    13561 cataaaatca aaaaactaga aatcattcct gaaaaaatat tttcgtagta atttgctaaa
    13621 gagagatgcg ctggcaagtc aaaaatagaa tatctttgga tctgatgttc tttcatataa
    13681 cggagcaact cgacacgttt ttgttgttca atgattggaa ttccttgtct ttgaccagaa
    13741 atcagtcgat ccagtatatc tttttcataa tgataagttg cttcgaccat ttgctggaca
    13801 ttccctgtgt tttttgcatg taagattgct tcgatcagtt tgttgctttt ctctaaactt
    13861 tccacaaatt ctttctcatt ctcatcttct ttcaacgttt caatcaaacg ttgcatctct
    13921 tcatagttat gattcagttc atcgaattct gtataagcaa gtttatgatc aaaaaaaagt
    13981 gggaatgcaa agagcacgac caacaataga ggaaataaaa agtttacttt gttttttagt
    14041 aagagattgc gttcaaatgt aagtaaagac atagttacac ctcatataat ttacgataaa
    14101 tagctaaaat ctcttccata tttgaggatt ctgtgacgat ttctccattt tttagaaaac
    14161 atgctttaga acaaatcgat tggatattcg cgatagcgtg ggaagaaaga agaatcgtct
    14221 tcccctcttt ctgccattgt ctgatgaggc tattcaagat atcaatactt cctgggtcta
    14281 atccgttcaa cggttcatcg aataacatga cagatgaatc actgatcaag taagcagcaa
    14341 gcaagacatg ttgtttcatt cctagagaca tttttccaat cggcaaagta aggtactcag
    14401 tcatcttcaa tcgttggaaa acagtttggc attctacttt gctctgccaa tagtatttga
    14461 tcaaagtcaa ataatcaaca gccgatagat agtcggataa ctgattcgtt gattctagaa
    14521 aaaagaaaga ccggcgataa tctgtataag cagtaggaga gatgttgtga agggacaatt
    14581 gatcataagt tgttggcagc agttgggcaa tgccattcag caaagttgtt ttgccaaatc
    14641 cgttcggggc aatcaaagca gctacttctc ctgattctac taaaagattc aattgtcgaa
    14701 tcacacgttt tttaccacgt ttcatgttca tgtttttgat cagtaatgtc atagataggc
    14761 ctccaatata aaatttaata acataataga atggaaaaca tctaaattaa atgctaacaa
    14821 aagttattgt ttgcatatta taaaaaaatt aaaataacag ttttatttaa aattgaagtt
    14881 ttctgatacc gaaatctttt tattttgctg acatactcaa acctttggca caaagtttcg
    14941 tgccaaagta cgactatttc tctttttagt aagcggatac aattagagta tcaaaaggag
    15001 agagggagag acaaaatgga acggacgatt cccaaaaaca acatttcgct aaaagcgagg
    15061 gtacaaaaat taggcagtac tttatcaagc atggtcatgc caaatattgg agcactgatt
    15121 gcctggggtg tattaacggc tctatttatc ccagatggtt atttaccaaa tgaggctttc
    15181 gctaccatgg taagcccaat gctaacttat ctgattcctt tattgatcgg ttatactggc
    15241 ggaaaagtaa ttgctggtga ccgcggatca gttgttgggg caattgcaac gatgggtgtg
    15301 attgtcggaa cagatattcc aatgatgcta ggcgcgatga tcatgggacc tcttggtgga
    15361 tatgccatca agaaatttga tcagctattc caaaaacgga tcaaatccgg ttttgaaatg
    15421 ctagtcaata atttttcagc aggtcttatc ggttttggat tagcgttatt aggtttttct
    15481 gcgattggtc cagttgtcga tgcattgact caagcaatgg caaaaggtgt agagatcatt
    15541 ttatctgccc atttgattcc attgacaagt atttttattg aaccagcaaa aatcttattt
    15601 ttgaataatg caatcaatca tgggattttg acaccattgg gaactgaaca agtagcagag
    15661 gctggaaaat ctattctatt cttgcttgaa gcaaatcctg gtccaggact tggcgtatta
    15721 cttgctttta ctttgtttgg caaaggagca gcaaaatctt cagcaccagg agccatgatc
    15781 attcactttt taggcgggat ccatgaaatc tattttcctt acgttatgat gaaaccgtta
    15841 ttattcttat cagttatagg cggaggaatg tcaggaagtt tcattttcca attgatggat
    15901 gctggactaa gagcgccagc ttctccaggg tcgatcattg cgattctagc gatgacaccg
    15961 ttcaattctt accttcctgt tattttgggc gtgattgttg ccgcagctgt ttcgtttggt
    16021 atttctgcag taattttgaa agcggatgcg aaagatacaa atgaagactt cgaaaaatct
    16081 gttcaagaga caaaggcagc taagcaagct tccaaaggtg cccaaggtat tcctcaagga
    16141 gctacattct ctggcgtaca aaaaatcatt tttgcttgtg atgcaggaat gggatcaagt
    16201 gcgatgggcg cttcgatctt gagaaaaaaa gtacaggaag cagacttgcc tcaaacggtg
    16261 accaatcaag caatcagcca actgacagat gactcgaata cattgatcgt tactcaggtc
    16321 gaactacaag aaagagcaaa acaaaaagca ccgagcgcgc gttttgtctc agtagaaaac
    16381 tttttgaatt cacctcgata tgatgaaatc attcaagaat taagcagcaa gcagaaaaca
    16441 tcagtttctg aaattgagaa tgagccagca gaagagtttc tttcagcaaa catcaaacaa
    16501 atcaaagaga ttctacttgt ccacgatgat cgttccggat cagcaacaat ggggatgacc
    16561 gtgctcaaag atatattaga caagaaccat ttaactatcc cgttaagaaa agtcaatatc
    16621 caagatttaa aagatgaacc tgattcactg atcgtagcca aagaaagttt agcggaaaaa
    16681 gtacagatgg ctgcacctca atccattcat ttatcagtca acagcatggt caatccgcaa
    16741 aaatacgaat cgattgcaca atatttgaaa cagacagctt aagggaggaa aacagcatgc
    16801 aaagtttgcc attcgacatg atcgagctca atcgatcttt taaaaccaaa gaagaagcga
    16861 tccgctattg cggtcagatg cttgtagaag cagggtgcgt tgatgaggaa tatatcgatg
    16921 ccatggtaga tagagacaaa atgttatctg tttatatggg gaattttatc gcgattcctc
    16981 atggaacaga tgaagcaaaa aaatatgtga aaaaatccgg catctgtgtc gttcaagtac
    17041 cagatggtgt agattttggt accgaagaag aagaaaagat tgcgactgtt ttgttcggta
    17101 ttgcaggagt cggagatgag catttgcaac ttgtacagca aatcgcactt tattgcagtg
    17161 atatggacaa tgttgtccag ctagcagacg cgctcagcaa agaagaagta acggaaaatc
    17221 tagcaattgc ttaaggagag agaaaaatga gagcagtaca ttttggtgca ggaaatatcg
    17281 gtcgaggatt tattggagag gttttggcag ctaatggatt tgagattact ttcgtagatg
    17341 tgaatcacac gatcattgat gctttaaatg aaagaaaaga atacgaaatc gaattagcag
    17401 atgaatcaaa agaaaaaatc actgtaaaaa atgtcaaagg aatcaacaat caaacaaatc
    17461 cagaaaaagt aatccaagaa atcgctgaag cagatttagt tactaccgcc attggcccga
    17521 atatcttacc ttttattgct gagttgattg caaaaggtat ccaagaaaga gaaaaggaag
    17581 gaagcacaac atctttagat atcattgcct gtgaaaatat gattggcggt tcagcatttc
    17641 tagaaaaaga agtgtataaa tatcttccgg aaacatcatt tactgacaaa tatatcggct
    17701 ttccaaatgc agcagtcgat cgaatcgtcc cattacaaca ccatgaagat cctttattcg
    17761 tccaagtgga acctttcaaa gaatgggtca ttgacgatag ccaaagaaaa aataaaaaaa
    17821 tccaattaaa aggggtttta tatgtagatg atctagaacc atatatcgaa cgcaaactat
    17881 ttagtgtcaa tactggtcat gcgactgtcg cttatacagg tgccttgtta ggttaccaga
    17941 ccattgatga agcaatgcaa gatgcgttag ttgtggcaca attaaaatca gttttgcagg
    18001 aaacaggaag tttgctgatt gccaaatggg ggtttgatgc agagcagcat catgcgtata
    18061 ttgaaaaaat cattcatcgc ttccaaaaca aaaatatctc tgatgcgatc acacgtgtcg
    18121 ctcggacacc attacgtaag ttaggttatc aagaaagatt tacacgtcca gtgagagaac
    18181 tacaagaaca taacttgact tgcccacatt tgacggcaac aatggggatt atttttaatt
    18241 actatgatcc tgaagatgaa caaagccgtc aattgcatga aatgaagatc catgaaaact
    18301 tggaacaatt gattcaagaa gtcacaggaa tcaatgatcc gaaaacaatc gggaatatca
    18361 agcaaaacgt gaaccgttat gccaagcaag tcgcttaaaa taggatacga aaaaggggaa
    18421 tgtgacgaaa tttttgtcac attccccttt ttcgaataac taggctgttt gtccttcaag
    18481 atagggcaga tccaattctt taccgtaacg ttgttctaaa gctaggcgga tcaaacgagc
    18541 tgccaggttc tcatttcttg caaggatagg tccatggaaa taagaaccga agacatttcg
    18601 gtaaatgaca ccttcagatt ggtcttcacc attatttcct tgaccttgta ccactttccc
    18661 caaaggtcgt tcaccttcac ctaagaaagt ccgaccattg tggttttcaa atccataata
    18721 agtttcattg aattcttcgt tatggataac gatatcaccg ataaaccggt tattttcctg
    18781 acttaacgtg tagtgatcca gtgcactgat tccttggatc ttttctccat tagctcccat
    18841 gtagtagtga cctagcaatt ggtagccacc acaaatggct aacatgacgc catcattttc
    18901 gatatagttg atcaaagaat ctttcttttt ctggatgtct tttgaaatga ttaattgctc
    18961 aaagtcttga ccaccgccaa agaaaaccaa gtcatattta tcagcatcaa aaggttcatg
    19021 tatactaacg atctccgtat ggcaagaaac ccccattttt tctgctatat atttcaacat
    19081 caaaaggttt ccgttatcac catatgtgtt catcaaattt ccataaaggt gggcgatatt
    19141 gagttcataa ttagccacgg ttcattcctc ctttgataaa tccttgagca gctagttctt
    19201 tacgaagctg caatacagca gtgtaagtag ctaaaatata gacatgctca gttggcaatt
    19261 ctttgatttt ttcgattact tctggtaatt cttttgtttc tgtcaattta ttttctggaa
    19321 tcccggcaac ttttagacgt aaagtcatat ctgtatgacg gtctcctcca gaaataacag
    19381 ctgggatatc catatcggca aagttttcaa aattaccatc ccaaatccag ctgacatcga
    19441 ttccgtctgc gtaattggca tttaataaag ccactaaaga aaatggataa ggagctagac
    19501 caatcatatc gattacttga ttgataccta caggattttt gacaagtact aatgtacatt
    19561 ttttcccatt gatattgatg acttcttgtc ggccgaatac tttctcgtca tatcctaaac
    19621 cttgtttgat tttatcagga tcgacattga agtactctgc cactgcagta gctgctaaag
    19681 cattgtagac attatacata ccgccaactt cgattccgta ttcatgacca tcgatcacga
    19741 aatctgctga cacattgtcc atccgtacca tatcagttaa tcgataatcc aattcaggac
    19801 gtttgaagtc acaatttgga cagtaatatt tccctaagtt tgcataagtg atcattttat
    19861 aatgcaagat gtgatgacaa tttggacata agacaccgtc tgtattgtaa tgagccattt
    19921 gttcacgatc ttcttcatgg tcaaagccat aatattttct aggattgact gtttcgatag
    19981 aattgaagat tggtgaatca ccgttactga taatcgttgc atttggtgac tttgcggcac
    20041 cgtctacaat cattttatag gtcgtataga tttctccata ccgatccatt tgatcacgga
    20101 aaatatttgt aaataagaac agttctggtt tcatatattc tgtgactttg ctcaaacttg
    20161 cttcatctat ttctaggaca gcaaactttt tctgtccttt ttttggtttt gcctgcaaga
    20221 aagtcgatac aattccctgt accatattcg caccagtagg gttggttaga acttcatcga
    20281 attgctggcg caaaatattg actgttaaag cggtagtcaa tgttttaccg tttgttccgg
    20341 tgacaacgac gacttggtag tcttttgcca aactatctag tatatgtgga tcgactttca
    20401 gcgctagttt acctggtaaa cttgatccgc ctttaaaaaa agtttttaat gcccattgcg
    20461 acgtttttcc aactgcaatc gcaaaatgac tgcgtattcc cattatgtaa cctccaaaaa
    20521 cgatttgctg acgaataaat tcaactaatc ataccatatg ttgaaaaaaa ggttaaattg
    20581 cttttcttat tcttaagaaa aggttacggc tgaaagtgca tgaaatcgga caaaatcgca
    20641 tgatttaaca aaaaaacagc ttgaaacaaa atgattgttt caagctgctg tgattttatt
    20701 attccctctt acctatattc ccattttaac cgataataat tttctcgctt ggatattcat
    20761 agcctagatc tcgtgtttct tttggcacga ataacatcaa tgtatatagc attccgatcc
    20821 gcccaataaa catcagtgta gcaatcgtga ttttgcccac aacagacaag tctccggtaa
    20881 tccctaaaga taaaccagtt gttccaaacg cagaagttac ttcgatgatg atcgagatca
    20941 gcgtttgttc ttctgtagca gataaaaaaa cgatacaaaa gaaacacata ccaagagaaa
    21001 gcataaagac aacgactgat tttcgcacat catcttgatc gattctccgt ccaaaaatat
    21061 tgatgttatc ttcacttttg aggaaggaat atagatacaa accgatgatt gctacagtag
    21121 ttgttcgaat cccgccgcct acagaactag gactgcatcc gataaacatc agtaaagaaa
    21181 aaatgatcag tgttgtgatt tgaaaatcac ccaaatcgtg aatctgcaga ccagcattac
    21241 gagtcgtaat cgaataaaac atcgaattga tccatttgac actcatattg gaatcttgga
    21301 ataaatggtc cttttccaat agataaatca agacagttcc cgaaacaaac aagataacaa
    21361 aagctaacac agctaatttg gtaaacaagg aaaaacgaaa cggaagcttc gcattggaac
    21421 gtttgtataa tagccattcc cggcactcca tcaatacagg aaaaccaatt cctccgacaa
    21481 aaatcaaaaa catgatcagg atcaagaaaa aatagtcatg tgcaaagggc ttgatggaat
    21541 ccccagtgac gtcaaaccca gagttcgtga cagccgatat cgcctgataa aaaccgtaaa
    21601 aaacggcatc acgccaacga tcaaaatagc ctctgtaata aaaataaata gaaaagaatg
    21661 tcccaaaaag taattgaaac cagattaaaa tagcaaaagt gatccgaatc agtcggacga
    21721 taccagacaa acgcggttga ttcatatccg tcatgatcag ctgtcgctgt ttcagtgtga
    21781 tccgtcgttt agaaaaaatg acaaaagcag tagaaatcat catgatcccc aaaccaccaa
    21841 cttgaaataa tatttccagc agtataatac cgttatcatt gaacacagaa ttgatatcaa
    21901 aagtcgatag tccagtcaca ctcactgtac tgattgccat gaacagcatg tccacaaaag
    21961 aaacatggct atctggttcg cgaaaaatcg gcatataaaa tagaacgagt gataagaccg
    22021 tcatcaatat ataataaaaa acgatgattt ggatcgatga gaaatgattg gcagcaaact
    22081 tctgtcctcg ccgctgcagc cttcgaaaga ataaatcaac atgcacagta ctatcctcct
    22141 gacaatagtc gtttctacca gtatacaagg ggaattagga atactcaaag aaattatcaa
    22201 acagataaca atacagcttt cgattaaaat agaaatggct tataataagg aaaatcctag
    22261 aaaaaagaag gaggaggaat aacaaattat ttaatgctca acaaatcgta gaaaaaatga
    22321 aaaatcaaaa aataaattat gatacagttc tgaaaaaaat gatcatgcaa tgggagaaag
    22381 aagaagtaaa gcctaagata ttaatacata catgctgtgc tccttgcagt acacacacat
    22441 tggaattcat gtctcaatat gcagagatca cgttattttt ttcaaattcg aatattcatc
    22501 ctaaaagtga gtatttgcga agattacatg aacaaaaacg atttgtagac caatttaatg
    22561 agaaaactga ccatcatgtt gcgctaatcg ttgatgaata ccgtccaaat gaattcacca
    22621 aaatggtttt aacaaaccat cttgaaaacg aaaaagaagg tggtgctcgc tgcagtgcat
    22681 gcttcaatat gcgattagat cttgttgcgc aaaaagcgca agaactagga tacgattact
    22741 ttggaagtgc cctgaccatc tcgccaaaga aaaatgcagc tttgatcaat cagatcggaa
    22801 tggatatcca aaagatttac gggacacaat acttgccaag tgatttcaag aaaaacaaag
    22861 gctatgaacg ctctttgcaa atgtgcaaag agtatgatat ttatcgccaa tgttattgtg
    22921 gttgcgtgtt cgctgccaag cagcaaggat gcgatctgaa agaaatcaat cgggaagcaa
    22981 aagcttactt aaaaacatca accgtagttt ttgaggaaaa ttaaagaaat ctttcggaaa
    23041 aacgtaagaa aaaaataaag aatttatggt agaaataagg tagactgtat aatttgtccg
    23101 tagtaaagta aggaaacaag aataaatttc aatgaaggaa gagataagat gcgaaaagta
    23161 gcacctattt tgaagccaat cgctgtatta acaatctcga cgattgtcgc gactactaca
    23221 ggtattgtga atagttccag ctaccgtgca ccaagttcaa gttctagtac tgtagaagaa
    23281 acaacaccaa ctacttcagt ctcgacatct gaaccaacaa caacggaaag tttgaatgaa
    23341 accactacga caagtacatg ggacgataca acaactagtt cgtcgtatga tgagacatat
    23401 acaactgaca gctcaagcga aacaagtaat acggtaccag atggcactcc atcggattca
    23461 accaatccaa gtacaagtcc ggatacaagt gctagctccg aaacgatacc aagcagtacg
    23521 actgtagatg ataacacgca aaatgatgat gcagcacgta cagcacagca aaaccaagat
    23581 tcaggaaata cccaaacgta taaccagcaa gcaggtgatt ctcaatgaca tttttactag
    23641 accttatcaa cggggtgcat aaattccttg gctatttaga catcagtcct aaatatctta
    23701 accgtggata tacgatttta agtgtgattc ccacgcttta tttattgaga attgtttatg
    23761 gactttggca aaaccaaaac tatcttcaat ttttcttata tggacttgca tttctagtgc
    23821 ttgtttattt tactgtttta aatgtatttt attacttttt agataaaaac acgaaagccg
    23881 atgtcactca gctttttgtg aagtatttac ctgatgaagc gttcaacatc cagacagaag
    23941 aatcgataga taatggaaat tcgatcgata aagtgaatac acaagaggtc atggtttctt
    24001 atgacgaaga ttatcaattg aaattagccg agaatatgcg gtatttgatt ggaaatggtg
    24061 agatcaaaac aaatgaactc ggtcgcatgg atggatttct ggtcgataga aatacattgt
    24121 atccttatta ctatgtcaag aaaacaggag agaaagagta tgttctaaat attggacgaa
    24181 gctactcgga catggaaaaa gtagggacca ttcgacttga ctcaacagaa gacacattgg
    24241 aacctgtcgg attgttcatc gtcggcggtg attttgtcaa agacgggtta cgctatcatg
    24301 agccttatcg tctgaaattg attgcaaaaa aggcacagtc gcaggaagaa ccagtggttt
    24361 atagtcgtag ccaaagaaga agacattcat aatgtgatga aacgccgtgt atcagtggtt
    24421 gcgataaaaa cgtttattcg gaataagggg gatgtgacac gtcttttgtc acgttccttt
    24481 tttatataac gagaaagata agacgaacac atcacttatt ctttcctttc atttataaac
    24541 attgtagaat aaagaaagta caacgaagta ttgtgaaaaa acgtaataaa taacgaggaa
    24601 aatacaagta ggaggtaagc tgtgaaagaa tttttgaaaa attgggggat tttgatcctt
    24661 gtattagcgg ctattttatt agctagagtg tacgtgttta caccagttac tgtaaacggg
    24721 cattcgatgg accctacatt aagtgatgga caacgattga tttcatctaa gatctcaaac
    24781 tatgaacgaa tggatattat tactacaaag gaaccggggg atgaagaacg gatgattgtt
    24841 aaacggatca tcggtatgcc tggagataca gtcaagatgg aaaatgacca gttgaccatt
    24901 aatggcaaaa agtatgatga accttatctg gatgagttca aaaaagaatt ttcagaagat
    24961 aagttacaag gagaatatgc ttatagctca ggattccaag cacaagcaga aagttcatcc
    25021 acctttacga gtgactttga atatactgtg ccaaaaggaa agtatcttgt tctaggcgat
    25081 aaccgcttga tttcaaaaga cagccgaatg tttgggttag tcgacaaaga tatgatccaa
    25141 ggaaaagttg ttttccgtta ttggcctctt tcagaaatta aaatcatgtg atgaaaaaat
    25201 aaaaagaagc tgtgacatgt tttttgtcac agcttctttt tccgaaaatt ccttcttatt
    25261 tcttggagtt gctcactttt tttgcaatct cattttaagc tttttggctg atggataaga
    25321 aaagcgaagc gtttttgttc ataaatagct tttccccacg atggaaggta tgactagtag
    25381 cagagacaaa gcccgttttt tccaatcgat tattcaattc ttcttggcta aagccattat
    25441 ggactttcgg atgactaatt tgttcattct tgtcaaagtc tacgatgatc aattgaccgc
    25501 caggagctaa aatttcataa agttttgtaa gaatattctc cgtatcagga atgtgtaaaa
    25561 gtacaagtga tagaaggatg agattagctt ggacagcagg aaattcgaca gaagcatcag
    25621 cgtggatcgt tcggacattt ttcagatctg ctgcttggat cttttcttct gccattttca
    25681 gcatagtttc tgaagcatcg gcaatgatca gttctttgaa tctttccgca agcggtaaac
    25741 taacaagccc agttccgcct ccgtaatcca gcaggacttt ttggtggctg tcgcgcggta
    25801 gataagtagt tagttcttcg cgaataatct tggctaatgc ttgacggtca ggggaatcat
    25861 aatggttagc gatggaatca aaaatatttt ttgtcatcaa atagctcctt acgtaaaact
    25921 ttgaaatttt aacttattat agcacgtgaa aagaaagaaa gcatgctata ctcaattcaa
    25981 aaagggagaa tctagaaaga atatgccgat atcgtttgta aaagatagag aggaaaaagg
    26041 aaagtgtgtc cgagaaatat tactagactt gcctgagtgg tttgggcttc ctgaatcaac
    26101 ggaaaaatat atcgaggaat caagtaaact acctttatgg tgtgaaaaaa gaaaagaaga
    26161 atatttaggc tttatcactc tttcacagac aagtgaagat actgccgaaa tctattctat
    26221 tgtatgggaa taaaaaaaga ctatcatcac caaggattag gaacaaaact ttttaaagaa
    26281 gcagaaggtt acgcagcaaa acattacaaa tatttgcaag tgaagactgt agacgagggg
    26341 cactactcta tatatgatca aactatttgt ttctacgaat cattaggatt ttcaaggttg
    26401 gaagtttttc caaatttatg ggatgaatgg aacccatgtt tagttcttgt caaaaaattg
    26461 gaacaaaagt gagcaataga tttaatacta atctgtgctt gatgaaaatt ctcactgtaa
    26521 aaaatgctga aaatcaagta taataccata ggaacaaact ggaaggtgaa aaagagcatg
    26581 gcacaactat tttttaagta tggcgcaatg aatagcggca agacgatcga gatcctaaaa
    26641 gtcgcacata attatgaaga acaaaataag ccagttgtct taatgacaag cggtattgat
    26701 acaagagatg gtttaggcgt tgtttcaagc cgaatcggac tgaaacgtaa tgcgatgccg
    26761 atatttgaag aaacagacgt atttgacgta attcagaaaa tggaaagcaa accctattgt
    26821 gtgctgatcg atgaagcgca attcttaaaa aagaaacatg tcattgcttt tacgagaatt
    26881 gtggacgaat tggatattcc ggttatggca tttggtttga aaaatgattt tcgaaacgag
    26941 ttatttgaag gatcaaaata tttattgctt tatgcagaca aaatcgaaga aatgaaaaca
    27001 atctgttggt tctgccacaa aaaagcaatc atgaatttac attatattga tggaaaccct
    27061 gtttatgaag gcgatcaagt gcaaattggc ggaaatgaag cttattaccc cgtttgtcga
    27121 aaacattact ttcacccatc aatgattaca gaaggagaat aagcatgtac gatcaattac
    27181 aagcaattga agaccgttat gaagagcttg gagaactttt aagtgaccca gaagtgattt
    27241 ctgatacaaa gcgttttatg cagctttcaa aagaagaagc aaacacgcgc gaaacagtcg
    27301 aagtttatcg tcgttataaa gaagtagtac aaggaatcac cgatacagaa gaactgcttg
    27361 gtgaaaaact ggatgatgaa atggctgaac tagcaaaaga agaattatct gaattaaaaa
    27421 aagaaaaaga agtcttagaa gaaaaaatca agatcttgct tttaccaaaa gatccaaatg
    27481 acgataaaaa tatcatcatg gaaatccgtg gagcagcagg cggagacgaa gcagcattat
    27541 tcgctggcga tcttttcaat atgtaccaaa agtatgctga agcacaaggc tggaaaacag
    27601 aagtgatgga agctaacgtt accggaatcg gtggatataa agaagtgatc atgatgatca
    27661 ccggagacaa cgtatattcg aaattaaaat atgaaagtgg tgcgcaccgc gtccagcgtg
    27721 ttccttcaac tgaatcgcaa gggcgtatcc atacttccac cgcaacagtt gtcgtgatgc
    27781 cagaagctga agaagtagag atcgatattg aagacaaaga tatccgtaca gatatctatc
    27841 atgcttcagg tgctggcgga cagcacgtca ataaaacagc atctgctgta cgtttgactc
    27901 acttaccaac agggatcgtt gttgctatgc aagatgaacg ttctcaaatc aagaaccgtg
    27961 aaaaagcaat gaaaatcttg cgtgctcgtg tgtacgataa gatccagcaa gaagcacaaa
    28021 gcgagtatga tgccaatcga aaatcagcag tcggaactgg ggatcgttca gaacggatcc
    28081 ggacgtataa tttcccgcaa aatcgtgtga ctgatcatcg tatcggatta actatccaaa
    28141 aattagatca gattttagca gggaaattag atgagatcgt tgatgcattg atcatgtatg
    28201 atcaaacatc aaaactggaa gctatgcaaa atgggtaaaa tgacctatcg agaagtcctg
    28261 tcacgggctt cttctttttt agaggatcat gggaaagaag catatagtat ccaattttta
    28321 tttttggaac gaaaacaatg gaaaaaactt gattggctcc ttcatatgaa cgaagagatt
    28381 tcagaagaag aacagcggtt gatcgaaacc gatctgcgac ttctgcttgc agatcatcca
    28441 cctcagtatt tgctaggata tgcagatttt tatgatcatc ggttaaaggt aactgaagca
    28501 acactgatcc ctcgaccaga aacagaggag ttagtcgaat ggtgtttaga cgagacgcct
    28561 ggtgtaccgt tagaagtgat agatattggg acagggactg gagcaattgc tattagtttg
    28621 aaagcagcaa gaaaaaattg gcatatatct gctgtggatc tttcagaaga agcattagaa
    28681 gtagcgaaag aaaatgctca gaaagaagga acgaaaatca gtttttatca tggagataca
    28741 ttaggaccag taatggatca gcaatttgat gtgattattt ctaatccgcc gtacatcagt
    28801 cggaatgaat gggaactgat ggatgaaagt gtccggtcat tcgaacctaa aatggccctt
    28861 tttgctgaga acgatggatt agctatttat gaaaaaatag cagttgaagc accaagcgta
    28921 ctaaaatcaa atggaaagat ttttttagaa atcggatttc gccaaggtga agcagtaaaa
    28981 aaaatatttc agcaagcatt tccagataaa aaagtggcga taaaaaagga tctttttggc
    29041 aatgaacgaa tgatccaagt ttatggttga agttgtggat gaaaaatttt ttatttgttt
    29101 ttttattata aaaaaacact tatttgacaa ggatgtaaac gactttttgg tttatcaaca
    29161 agtttatcca ctattgacaa atagattatc cacaaacagt ggaaaacttg aggataaact
    29221 cagacaaaat aagaatgtat gaaaaagggg ttgtggataa actgtggaaa cgaaacgata
    29281 tgatgaaaca gaattgcaag aggcagccga agcactgaaa gaaggagaac ttgttgcttt
    29341 tcctaccgaa acagtatacg gattgggcgc caacgctctt ttaccaaacg ctgtcaagaa
    29401 agtgttttct gtaaaaggga gaccgcaaga taatccatta atcgtccatg tcgcctcttt
    29461 tgaacaagta aaagagtatg tggacaactt tcatccggca gcagagaaga ttgtgaagaa
    29521 cttctggcct ggaccattaa ctttgatatt taagatcaaa aaagacactt tgccctcagt
    29581 tgtgacggga ggattatcca cagctgcatt tcgtataccg gataacaaaa aaacactaga
    29641 agtaatcgaa ctttccggtg ttccgcttgt cggtccaagt gcaaatacgt cgggaaaacc
    29701 aagtccaacg actgcagatc atgtatatca tgatctacaa ggaaaaatta ccgggattat
    29761 tgatgatgga gctacgcgaa ttggtgtaga atccactgtt cttgatttaa gtgatccaac
    29821 agccatgcct atgattttac gaccaggtgc agtaacgaaa gaacaaatcg aagcagtcat
    29881 cgaatctcct gttgctattg atcagcatct tgtaaaagaa aatgaaacac caaaagcccc
    29941 tgggatgaaa tacaaacact actcacccga tacacgtgtt ctgatggtca gagatggcga
    30001 ttggtcaact gcagttcaat gggcaaaaaa taagaagatc cgtgcaggtg tcatagcaag
    30061 ccccgaaatt gcggatcaag tgcggacaga tactgcagct gtttatatgt ataacgacaa
    30121 ctcagtagaa gcggcggcta aaggattgtt tgcaggtcta agaggattag atgaaccaac
    30181 acttggatta gatttgattt ttgtacaagt gtatccagaa actggattgg ggaatgctta
    30241 catgaatcgc ttgaaaaaag cagcaggaca aaattatttt gaaaaatgat caattggtta
    30301 ttgtcgcatt cttttagtat gatacaatgc tatcaagtaa atcttctatc agtgaacgaa
    30361 aaactaagcg taactaatcg taatagaaga gatacgaata tttggcaatt tgtttttgat
    30421 gggaaaaata aaattgtagg aaaataaaaa ggagctgttg tttgtggtag attacaaaac
    30481 gtttgaccct gatctttggg ctgcgatcgc caaagaagaa gaaagacaag aacataattt
    30541 ggagctgatt gcctctgaaa actttgtctc cgaagcagtg atggctgcac aaggaagtat
    30601 cttgacaaat aaatacgcag aaggttatcc agggcatcgc tattatggtg ggtgtgaatt
    30661 tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa gaattattcg gagcgaaatt
    30721 tgcgaacgtc cagcctcact ccggctctca agccaacacg gctgcttatc tcgctttggt
    30781 agaaccaggg gacacgatct taggaatgga tctttccgca ggcggacatc taacacatgg
    30841 atcaccagtc aacttcagtg gcaaaaccta tcactttgtt gcttacggtg ttgatccgac
    30901 aacagaagtt attgattata atgtggtacg tattttagct agaaaacatc aaccaaaatt
    30961 gatcgtagca ggtgccagtg cttacggacg aacgatcgac tttgcgaaat tcagagaaat
    31021 cgcagatgaa gtaggcgcaa aactgatggt agatatggca catatcgcag gattagtagc
    31081 agcaggactt catcctaatc cagttcctta tgcagatatc acaacgacta ccactcataa
    31141 aacattgcgt ggccctcgag gcggcatgat tttgacaaac gatgaagcat tagcaaaaaa
    31201 aataaatagt gcggtatttc ctggtattca aggcggccct ctagagcatg tgattgcggg
    31261 taaagcagta gcattcaaag aagcattaga tcctgcattt aaagaatata gtgaacaaat
    31321 catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa gcaattggaa ccagagtcat
    31381 ttcaggggcg acagataatc atctgatgtt gatcgatgtt cgcgagttag gtataaatgg
    31441 aaaagaagca gagagcattt tggacagtgt gaatatcact gtaaataaaa actcgattcc
    31501 ttttgaaaca ctaagtccat tcaaaacaag cggtattcga atcggcacgc cagcaatcac
    31561 tactcgcggg ttcaaagaag aagatgctgt aaaagtggct gaactagttg tcaaagcatt
    31621 acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa acaggtgtac gcgaattaac
    31681 tgaaaaattt ccgttgcata aaaaataaaa atttaaattc cattagtaaa cagaaaagtt
    31741 caatgttggg cttttctgtt tattttttgg gaaaacggat tctttgacaa tatcggtgat
    31801 gctctctagt atatgaggtg taattttagt cttcacacta aatctcaggg aggaaaagtc
    31861 atgactgatc gtatctcgtt agaaaaggaa gcagtagcat tcagtgatgc aaatgcgcct
    31921 catccgcgta tctatgaact agcaccggaa gaaggaagag ttttactaga agaagtacaa
    31981 gaatcacctg tgaacaaata ttccgtcgat attgaagact tgatggtgga tactggcgaa
    32041 tggggaaaac tcaatattcg tctcgtacga ccagaaggga atatggataa attaccagtt
    32101 attttttata ttcatggagc aggctgggtt tttggcagtg ctcaaaccca tgataaattg
    32161 atcagagaac ttgcggttcg tacgaattcc gtcgttgtct ttccagaata tagtcgatca
    32221 ccagaagcaa aatatccaac agcaattgaa caaaattatg ctgtgttgca acagctgaat
    32281 aaattagcca agtcaaaaaa tctggatctc gagaatctaa tcgttgcagg agattcagta
    32341 ggtggtaaca tggctacagt catgacgatc ttaacaaaag aacgaaaggg cctcccaata
    32401 tccaagcaat tgctgtatta tccagtcaca aacgctgatt ttgatacaga ttcctatcat
    32461 gaattcggag aaaactattt tttgacaaga gaaggaatga tgtggttttg ggaccaatat
    32521 acgacgaatg aagaagagcg tgctgaaatc acagcttcgc ctttgagagc aaatataaat
    32581 gaactaaatg atcttccttc agcaatgatt ttaacgggag aagcggatgt attaagagat
    32641 gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg ttcctgttac acaagtacgc
    32701 ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta tggatcagac aaaggcaacg
    32761 cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa aagaataagc tttgcttgtc
    32821 cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa aaatggcgag tttgactagt
    32881 caatcacttg attttgtttt acaattaaaa agaaacgaca gaacaaagga gagcttaaaa
    32941 aatgggcaaa tttcaagtga tcgatcatcc attgattcaa cacaaactaa ctattattcg
    33001 ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc gatgaaatcg ctatgttgat
    33061 ggcatatgaa gtatcacggg atatgccatt ggaagacatc gtgatcgaaa caccgatcac
    33121 tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg attattccaa tcttgcgcgc
    33181 aggtattgga atggttgacg gtatcttgga attgattcca gctgctaaag tgggacatat
    33241 cggtctttat cgagatgaag aaacattgga accacatgaa tatttcgtca aacttccaga
    33301 agacattgat gcacgtcagt tgtttgtagt agatccaatg ttggcaacag gcggatcagc
    33361 aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg aacattaaat ttgtttgttt
    33421 ggtagcagca cctgagggag taaaagcttt gcaagaagcg catcctgata ttgacatcta
    33481 tacagcttct ctagatgaaa aattgaatga acatggttat atcgttcctg gactagggga
    33541 tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg aaaaagggtg tgacacaact
    33601 tttgtcacat ccttttttgg tcatttttaa cgtttgatgc agaacagctt tttcacagct
    33661 ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga tggtcaaatt caaatctttt
    33721 ttagttcttt gtagttaacg attactacac ccttactttg cgtcatcaag ttcgcatttt
    33781 ctgcagtttc atcaatctca acaacagcgg aatttttcaa ttgctttgaa atcgttccag
    33841 tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt gatcttgaat ttttcaccaa
    33901 tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt tgccattttc ataaaacctg
    33961 cctttcacat caattatacc acgttttatg aaaaatatca tgaaattaaa ctaattttcc
    34021 atcggactct ttacaatcag ccaaatagag tatataattt cttttggata aggccagctt
    34081 agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc gtaggttcga tccctatagc
    34141 tggcattaaa agagaagaca gatatatcaa ggatttttaa tccattgata catctgtctt
    34201 tttgtttaaa ggaaataaag tatgctttct tagcaataga gcatgtatta tttctataaa
    34261 aatttaggag aataaaacga ctagcaatat agctgtgaaa tcaaatatca catgaactgc
    34321 ccaacttgta atgatcgagt tgcttttaat ggcagcttgg ttgaataaca atcttgccac
    34381 cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata tttccattat cataagtact
    34441 gtaatggata aatccaaaga tgattgctga caagaaacta gcgacaggaa tgctgaactt
    34501 actagaaaaa atagcgagaa aatacactga gaacaattct tctccaagta tcatgatagg
    34561 caaaataata aataataacg ggctgaaagc ctcatttatt ggattgcctg ttaaacccca
    34621 tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg attactacat tgataaaaaa
    34681 atatttggct atatttttga caggagcgac aggtttcgag aacatttttt tcgtatcttt
    34741 tttaccaaaa acaagtgtaa atgctataaa tccagtgata gttaaagaaa aaatgctaat
    34801 aatggatggc gcaaatagca accctaacaa accgagtaca acgacaatag tgcccaatat
    34861 ccctttttta agttctattt tttttcctaa aatgttattc atgataataa ctcctactat
    34921 tcagtttttg aagatagagt cagtatacat gaagagttaa aataggcaat gtttttttat
    34981 ggatatttgt attgctaaaa atttatctta tatattcatt ttgattatac tacttttatt
    35041 tgtaaaaatt ttctagcaaa accaagtgct tgcaactgat taagcgtaca attttttaga
    35101 tgttccgagc gtacttcaat catttcaaag gagttgctac ttaaatcgat attttttaaa
    35161 tcagtatcaa aaaagctagc attttctaaa tcattagtag aaaacattat tttagtgagg
    35221 gaacagtcta caaaatctgc gcttgataag acagagtgct caaaggtact ttcttttatg
    35281 tttgaaccag ataaatttac atagtccatt ttacaattct cgaataacgt gttcccaata
    35341 taactttcca tcaatttagt acctgttaat ttacaattga caaatttcac gcgatgcaac
    35401 atgctttttg tcaatataca gcctgaaaaa tcacagtttt cgaatataca gtcggtaatc
    35461 tccattcttt gaaaatcatt ggaagcaaaa aatgcatact tgaaaataga tttgtaaata
    35521 attggatggc agattatttg gttttcgatg acctcttttt gtgaaaggat attatacagt
    35581 tcaaaatctt cgttttcata gatatgaaaa aaggatcctt tattcaagct tgcttcatta
    35641 actttaggaa aaatcatatt taattacctc cattttcata aagtcatatt aacaaaagct
    35701 aaaccaactt acattagcag aaaatgagat aggttttcgc ctttttcgat aacgatagtg
    35761 tcgctatctc ttgaaacgtt cttagaattg ccctgagaga cacaaattag gcgtaattct
    35821 aataaaaatc ttagaataaa aatttttact gatttaattt agaatgtttt taaaataaaa
    35881 atcgttgcca taacagtgta ttgaaaggtt ttaacaatcc agtaatgatt taaaaaaatc
    35941 tagatgtagc gtatactttg tttatagaat gtagtgggaa gaaatatatt tttgggagga
    36001 aatcgtgatg tctaaaagtg aagaaataga aaacatggta ctaaaattat atgatctcgt
    36061 tttaaatcca gagatcaaag aaaaggaacg tatacttttg atagacgcaa agacaggctt
    36121 agaaaaaggt cagtattatc ctaaagtcat aaataatttg gaacgtagtt tacgtccgtt
    36181 agcaatcagg ggagaattgt ctaaaccagt atcaccgttt tatatggaga tatcaacaat
    36241 aggaaaattt gaaaaagaat taggtcgagg aatggcttcg gcaccgatta cttttgggca
    36301 tttataaaaa cgagttattc atctcaatga attaaaaagt atagtcaatc tcataatgca
    36361 ggctaggttc atttatttga acagagtctg tattttttta ttctaaataa agaaacagat
    36421 gtttctttat attgtatttt atcctttaat taacacaaaa acagctagta taaactaata
    36481 atgttaatta aaagtgtatt ttatgaaact atcgttattt attaatgttg catttttg
//
LOCUS       DAIGQM010000024        33918 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.024, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000024 DAIGQM010000000
VERSION     DAIGQM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.024"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..383)
                     /locus_tag="NOA48_001170"
     CDS             complement(<1..383)
                     /locus_tag="NOA48_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HCI0789445.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVI"
     gene            complement(497..1081)
                     /locus_tag="NOA48_001171"
     CDS             complement(497..1081)
                     /locus_tag="NOA48_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCI0789446.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(1208..1639)
                     /locus_tag="NOA48_001172"
     CDS             complement(1208..1639)
                     /locus_tag="NOA48_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0789447.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(1657..1977)
                     /locus_tag="NOA48_001173"
     CDS             complement(1657..1977)
                     /locus_tag="NOA48_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0789448.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENK"
     gene            2277..2417
                     /locus_tag="NOA48_001174"
     CDS             2277..2417
                     /locus_tag="NOA48_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789449.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            2715..2972
                     /locus_tag="NOA48_001175"
     CDS             2715..2972
                     /locus_tag="NOA48_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HCI0789450.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(2943..3251)
                     /locus_tag="NOA48_001176"
     CDS             complement(2943..3251)
                     /locus_tag="NOA48_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789451.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            3329..4075
                     /locus_tag="NOA48_001177"
     CDS             3329..4075
                     /locus_tag="NOA48_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCI0789452.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            4090..4293
                     /locus_tag="NOA48_001178"
     CDS             4090..4293
                     /locus_tag="NOA48_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789453.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            4309..4647
                     /locus_tag="NOA48_001179"
     CDS             4309..4647
                     /locus_tag="NOA48_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCI0789454.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            4634..4804
                     /locus_tag="NOA48_001180"
     CDS             4634..4804
                     /locus_tag="NOA48_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789455.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(4902..5567)
                     /locus_tag="NOA48_001181"
     CDS             complement(4902..5567)
                     /locus_tag="NOA48_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789456.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            5622..6320
                     /locus_tag="NOA48_001182"
     CDS             5622..6320
                     /locus_tag="NOA48_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HCI0789457.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDTVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            6498..6838
                     /locus_tag="NOA48_001183"
                     /pseudo
     CDS             6498..6838
                     /locus_tag="NOA48_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6831..7502
                     /locus_tag="NOA48_001184"
     CDS             6831..7502
                     /locus_tag="NOA48_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI0789458.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            7508..8194
                     /locus_tag="NOA48_001185"
     CDS             7508..8194
                     /locus_tag="NOA48_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789459.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            8197..9027
                     /locus_tag="NOA48_001186"
     CDS             8197..9027
                     /locus_tag="NOA48_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI0789460.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLGSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSNEHLRLAKKLQSNLTEDFPKEMTKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            9044..9895
                     /locus_tag="NOA48_001187"
     CDS             9044..9895
                     /locus_tag="NOA48_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0789461.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            9892..10251
                     /locus_tag="NOA48_001188"
     CDS             9892..10251
                     /locus_tag="NOA48_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI0789462.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVIDVKGMQTKDFKIKAKLFCHKYQV
                     PLILAKKYRNTFKEERF"
     gene            10266..10427
                     /locus_tag="NOA48_001189"
     CDS             10266..10427
                     /locus_tag="NOA48_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0789463.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIVNL
                     RREIRRLEE"
     gene            10430..10729
                     /locus_tag="NOA48_001190"
     CDS             10430..10729
                     /locus_tag="NOA48_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789464.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKIGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            10729..11046
                     /locus_tag="NOA48_001191"
     CDS             10729..11046
                     /locus_tag="NOA48_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI0789465.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLYQDRFKFVEKYREILDEYME
                     EAE"
     gene            11043..11246
                     /locus_tag="NOA48_001192"
     CDS             11043..11246
                     /locus_tag="NOA48_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HCI0789466.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            11243..11536
                     /locus_tag="NOA48_001193"
     CDS             11243..11536
                     /locus_tag="NOA48_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789467.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            11566..12006
                     /locus_tag="NOA48_001194"
     CDS             11566..12006
                     /locus_tag="NOA48_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0789468.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            12081..12548
                     /locus_tag="NOA48_001195"
     CDS             12081..12548
                     /locus_tag="NOA48_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI0789469.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(12948..13301)
                     /locus_tag="NOA48_001196"
     CDS             complement(12948..13301)
                     /locus_tag="NOA48_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789470.1"
                     /translation="MAKIDDYRSDMIEYIELFAKNSNNNIIIQTGGATICGTPIDFDA
                     EVKVNPLIDAMMDSFAEFRSKKIDDIEKDDEQSLVVKSIFLKDVTIIGERTTNIPFLV
                     VFADQISAISLGNLE"
     gene            14019..14090
                     /locus_tag="NOA48_001197"
     tRNA            14019..14090
                     /locus_tag="NOA48_001197"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14052..14054,aa:Lys,seq:ttt)
     gene            14423..14767
                     /locus_tag="NOA48_001198"
     CDS             14423..14767
                     /locus_tag="NOA48_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI0789471.1"
                     /translation="MTEEFYRWLLQLIREDCLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            14772..15053
                     /locus_tag="NOA48_001199"
     CDS             14772..15053
                     /locus_tag="NOA48_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789472.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            15156..15470
                     /locus_tag="NOA48_001200"
     CDS             15156..15470
                     /locus_tag="NOA48_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCI0789473.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            15448..17142
                     /locus_tag="NOA48_001201"
     CDS             15448..17142
                     /locus_tag="NOA48_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI0789474.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            17162..18340
                     /locus_tag="NOA48_001202"
     CDS             17162..18340
                     /locus_tag="NOA48_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0789475.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKDFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            18303..18989
                     /locus_tag="NOA48_001203"
     CDS             18303..18989
                     /locus_tag="NOA48_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCI0789476.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            18989..20149
                     /locus_tag="NOA48_001204"
     CDS             18989..20149
                     /locus_tag="NOA48_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0789477.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            20159..21034
                     /locus_tag="NOA48_001205"
     CDS             20159..21034
                     /locus_tag="NOA48_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789478.1"
                     /translation="MKYILCQLAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            21031..21342
                     /locus_tag="NOA48_001206"
     CDS             21031..21342
                     /locus_tag="NOA48_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789479.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            21332..21685
                     /locus_tag="NOA48_001207"
     CDS             21332..21685
                     /locus_tag="NOA48_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI0789480.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            21675..22076
                     /locus_tag="NOA48_001208"
     CDS             21675..22076
                     /locus_tag="NOA48_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789481.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            22069..22473
                     /locus_tag="NOA48_001209"
     CDS             22069..22473
                     /locus_tag="NOA48_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789482.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            22485..23093
                     /locus_tag="NOA48_001210"
     CDS             22485..23093
                     /locus_tag="NOA48_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0789483.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELEAKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            23113..23475
                     /locus_tag="NOA48_001211"
     CDS             23113..23475
                     /locus_tag="NOA48_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789484.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            23478..23660
                     /locus_tag="NOA48_001212"
     CDS             23478..23660
                     /locus_tag="NOA48_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789485.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            23677..27096
                     /locus_tag="NOA48_001213"
     CDS             23677..27096
                     /locus_tag="NOA48_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI0789486.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFIDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            27147..27884
                     /locus_tag="NOA48_001214"
     CDS             27147..27884
                     /locus_tag="NOA48_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0789487.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFTLNDYVFSFEGLVVGTDIVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            27894..30185
                     /locus_tag="NOA48_001215"
     CDS             27894..30185
                     /locus_tag="NOA48_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0789488.1"
                     /translation="MIDNLLTIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREVA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNVGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            30209..32386
                     /locus_tag="NOA48_001216"
     CDS             30209..32386
                     /locus_tag="NOA48_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789489.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGNPNLMANINADSFS
                     QGSGALSVVDDGDEVVITLDPNHKLEVLKPKSQPALLTGKTYTVSVEIMLEGDFTGDP
                     SKIGLRYIKMPNWVSELYTRNTLTATKGVWQKLTGTVKITAASDNAESWLIMLQNKDA
                     NNSLSGKLRLRHAKLEEGSTATPYQPNLLAEPYNMCREYPNENIADPKVKFPIKSGDH
                     QIYQGYMEEDLMIGQTYTITLKGTKPASQTFVAYNHWTVRLGELKPVDGLTDVWSLTF
                     TPTNVAAMPKLFRVYQYPQSTVGACQIDWLKIEKGNTRTPNISEYKYRGTGMRDSNNP
                     KDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDA
                     QTKANANATAIDERINDTATTAFYGAQGEVSNKTKVAEYGVGTGYTTTAVGETHFERQ
                     SNGYVKCLKAGKYSISAQIRVQLGGKYASWLYTDLYKDGTSVDNLVSYGVDALQNRFA
                     ASGNIVTDLEVNDVLNMRTEIGVADGILQFTSCRTLVLTRLSD"
     gene            32464..32706
                     /locus_tag="NOA48_001217"
     CDS             32464..32706
                     /locus_tag="NOA48_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HCI0789490.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGVTIIGYFLTKL"
     gene            32722..32919
                     /locus_tag="NOA48_001218"
     CDS             32722..32919
                     /locus_tag="NOA48_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0789491.1"
                     /translation="MILPDKYYQVIKWAVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            32930..>33918
                     /locus_tag="NOA48_001219"
     CDS             32930..>33918
                     /locus_tag="NOA48_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI0789492.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHNKATFEKNYKAYVELARDSAKKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYGTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHD"
BASE COUNT        12050 a         5202 c         6921 g         9745 t
ORIGIN      
        1 ttaataacgg tggattttac atggtctttc gcatacttat ttaaaaagcg ttgatatcca
       61 actctatcta aatcagaaat caataccgct ggcatatatt tctttatgtt cattaacgta
      121 tcttcgtatt ttctataagt gataggagat actgttcctt ctttataaag ttgcatccaa
      181 tcctcaaagt aatctgataa taatagattt ttgcgatccc ctttaaggcc tttgttcaag
      241 ttatattcta attcgttggc ggcatctttt gcttcgcctt ttgtcttaaa tcctgatttt
      301 cttatcttcg tgtattttcc gtcatctttt ttgtatgaaa tttcgtattg ccaactattt
      361 ccacgtttga ctaatcttgc cataattgaa tctactctct ttctctgata caataggcac
      421 tataaagaag cctactgtat aggtttgttt ttcttagaac acgcttgctt tggacggtgg
      481 gcgtgttttt tatttattat acagttgctt taaaaatagc tgctttttca aatgatacta
      541 aaggagagaa gtggatttct atttctccct tttggtttaa cgtgaaatga gcagttacat
      601 ccatttgttt tcctggagca acagatccca ttgtattttc gttggcatat gtctctgatt
      661 ttttgtcatc tggtccatat acttccacat ctgtacctac agggatatct gaatcgccat
      721 cattttttac ggtataagta atttttacta cttgtgcagg ttggttttct tcaaattgat
      781 ttctttcatc agttagttct acactattta gtgtatattc agcatcacca acttttacag
      841 tgtcaccaat cttatagaag gtatcgcttt tttcttcttt agaagatgaa gcagaggttg
      901 aagatttagt tactttttcg ccaccattat cacttgcttt attactatct gatccaccat
      961 ttaaagcaga accaataatt ataattaaaa ttactgctaa tacccaaaac catacttttt
     1021 tgtaaaaagg tttactaact ttatacattt ttccgtcttg acccataact ttttttgcca
     1081 tttaaatatt cctcacttct tgttataata tatttgcgat ctcagaaatg aggtatgagt
     1141 ccgtgtgcca gcacgggctt ttttaatgtt ttgctgaaat cggttttttt aataattctt
     1201 gatgtattca tacatattgc cttgcgtaag aatatttttt cttaaaatag cattggcaga
     1261 cagcataaca agtgtatctg agcttattct gaatagaata atactccata aatttttcga
     1321 gattaaactg agattcatca gtcagttcgt tctcaatata gatatttaat aaaattagaa
     1381 tagctatttt atctgcttct gtttcaaatt ttgagtgaaa agttgtagaa gtatcgtaca
     1441 aaactgaaaa ttcaaaatga gaggcgctga aatgtgcaag ttcatgagat aaatgaaagg
     1501 cttctgcagt ttcaccgtat agattttcat tcaaaaaaat gattctgggt tttggatagt
     1561 agaaaccagg ctctttcatt tccatataaa ctactttcaa attgtattcg ctcaacattt
     1621 ctttcaattt caaatacata taaaccatca ctccaactat ttgttttctt ctaaagcttt
     1681 agcaattgca atcgctttac gcattgtctc cttagatatt tcttttccgt caaaagaaaa
     1741 tacagtatcg ttttctgata aatccacatg tttaggggtt tctctttctt ctctacctag
     1801 aaggtagtct acagagactc caaagtaatc agctaaccga gctaactcaa tagaattagg
     1861 agtttgtctt ttccaacttc ctaaatatcc attcgaatac ccgaaattca tttcgagctg
     1921 tctaatggat aatccttttt cttttgctaa ctcctttatt atttcgtaag tattcattga
     1981 taaatcaacc tttctgaatg cttacaaaaa aagtttagat aaataatgta aaaatagttg
     2041 acttatatac attattaatc tatactatgt tttgtaaaca agtttaacaa ctaaaaagac
     2101 aacaaaaaat actattgatt aataaatgcc aaccgccaag aaagcttttt aaatcaaagt
     2161 ttatatgtct tatttaacta tgcatttagt atagattatt aatctaataa agtcaacgca
     2221 gttttttaaa aagttgttaa atttgtttac gaatataaaa gaaaggagag aagaatatgg
     2281 aaaaaacagt ctcggcaaaa atcgaagatt tgaaattaga catactgaaa caagcaaaag
     2341 tggcgatgga acacgcggta gataaagaag actctgccat ggttgcagcc atagcagaga
     2401 ttttagctca cgtttagtca tcgtttttac ggtcttctgg aagctgacca tagataacag
     2461 cataatgaat atctaaataa gcttgaacaa tttcttttgg cgaaattgat tcgcctttag
     2521 tagatacttg tgattcgtga tttagccatg caacaactaa atccgcagcg atttcaaacg
     2581 gcgttacact ttgtgtcagt tgccataaag aatttcacaa tatgtatggt cgtggtaata
     2641 ataccaaaga gcaatttgag gaatttatgg aaattaaaaa atacaaaaaa tcatttatta
     2701 aaggaggcta aacaatgaac aaggaaatga gccaaacaat caaggtacaa aaaatgatag
     2761 atgatctaac acatggaatt gatagccaag ccgataaaat catcaaggaa ttgcaaggac
     2821 aaaaagttaa ggatgcaaaa atgcttctca agactatcaa ctttgaaatg aatccaacaa
     2881 aaagaaagct cgccgatgtg ttggaagaaa agttggcttc cgctatcaac gagcaagaat
     2941 tactatttga aaccgatact tttaacagct gatgttttat agatgacagt ttcatccgaa
     3001 tctatatcat cgccgagaga aaagaatgtt gcttttgaca aaaagccgat aagacctaca
     3061 agcggtcttg atgttgcaag agtagatacc ccaatatcac cttgcaaggt attcacgtaa
     3121 atttgagaag aatagaacat tccatctttt tcttcgatat ttgacgcatc atcgtatcca
     3181 acgaccaaag tatcggcaaa tattttgatt ttttctccat caagcatagt aattacaaat
     3241 tctggtttca taaattttca cctccttaac aattatttca gcctgtcaca ctgataagga
     3301 aattatacca aagaaaggaa tgagaaatat gaatacacca caaattttta atttcgagca
     3361 aaacgaagtt cgaactattt tagtaaatga tgaaccatat tttgtaggaa aagatgtagc
     3421 agacgttcta ggatattcga atccgcaaaa agctattcga gatcatgtgg acttggagga
     3481 taagacgcag aacgattcgt tcaccgtcaa tggaacagca gttgttttga ttaacgagtc
     3541 aggcctttac agtttaatct taaaatcaaa acttccctct gccaaaaaat ttaaacgttg
     3601 ggtaacgagt gaagtccttc caacaattag aaaaacaggt agctattcaa acgtacctca
     3661 aagttttgca caagcattgc gtttagcagc ggatttagaa gaaaagaacc aattactcga
     3721 acaacaaatt gccgagtacg aaccaaagat tagctactta gatacgattc tttcatcgac
     3781 agatacggta gctacttctc aaattgcagc tgattacgga atgtcggcaa ttgctctaaa
     3841 caaattgcta aacgagttag gtgttcagca taaagttagc ggacaatgga tactttaccg
     3901 aaaacatatg aaccaaggat acacaaaatc gcacacaagt gagataccga aagccgatgg
     3961 cggcactaaa gttgtaatga ataccaaatg gacacagaaa gggcgagtgt ttatttacaa
     4021 cttattaatc gcagagggct attaccctca aatggattta gaggaaattg gttagaaagg
     4081 agttttagta tgactgacat tgcagaaatc actcaacgag atagagaaaa aatcaaagaa
     4141 tatgtcgaaa gttcgaagtt cttaacttac accatgcttg ctgaaagatt tggaattagc
     4201 aaaagctact tatctttaat tttaaacggt aaaaagactt ctgcagaagc aaatagaatc
     4261 atagattcga ttattactat gtacgaattg taaagggagg aacagctaat gcaatatcta
     4321 gaagcgaaaa tcccagttcc agaaggctat gtaattatct cccaagtgga ttatgaggag
     4381 ttaaaaaaag ctgatgatac tggtagatgg atgacgttgc cagaagtgct agaacggatt
     4441 aacagaaaat atgattggtt tacttctaga gttttaaaga acccaagata tagaaatatt
     4501 atcgatatcg aaaaaaataa aaatggattt gtctattatc cagttgaagg aagagacaca
     4561 tatctatttt taagaagtaa aacacttgaa tttttagaaa caaatttttc ggaaatctta
     4621 aggaggcaag cggatgggaa aatttaatag agcgctagta ttcagcgcac cgctaatcat
     4681 ctacgcttta ggactttggg gaagcagaca agcgttgata ggaacgattg tttacatggt
     4741 ttggattttt atggggctgg atgaagctga gtacaaaaca aaaaagccag tcgggaggga
     4801 ctgactaatg aaaaaaagtt taatgactat aaacgaaaaa caattgaaag aaaattttaa
     4861 tgatctcatc aaagaatttg taaaagaaac tggagaattt cctaatcaaa ttcatctagt
     4921 tgcggagggg catagccagt atcaagctgt gaaatttgag atgaagaaac aaatctattg
     4981 aatttagcag tacctctact tgtaagaaca tttattgtaa tgtttttttc gactaaagat
     5041 tcatcgtatc taaaaaccaa cgtagtaatt tttgactcat acggtggaat ggtaataggt
     5101 aatgacaacg gaggaaattt tgatagatca gcaccttttt ttaaagattt accagaatac
     5161 gcacgtatac catgtggaag ttcgtcatac attgatttta ccgttacaga ataattatca
     5221 ccaatcattg taaaagcatt taaatgatca ggaattccag aaatcgaaaa ctcaataatt
     5281 gtaacaggta aagaactgtt atttgttaac aatacagaat ctataatcct gaatttattt
     5341 tgatggtaaa catctggttt ggaatcactt tctctatcta tcaaccattc ttcgcattca
     5401 gcgaagaaat ccaattttaa attaaatttt ttgttttttc tatctgtata ggagatataa
     5461 aaagcaaatg ttgaaaatac tagagacgta ataggcaaaa taaaatcttt aatggtttta
     5521 acaatgttat tccagtcaaa ttgtttaata aagtcaataa gactcaattt ataccaccac
     5581 cattttttat ctacattata tcaaagagga gagaagaaat aatgcaagaa ttagtaattt
     5641 tgaaaaataa agaagctgtg actacgagtt tgcaagttgc agaaagtttt gagaaaaagc
     5701 atcaacatgt tttaagagat attgatgcac tgaaaaaaga tgtgtccaat tttggacaga
     5761 tgttttctga aggtaatgaa ccagattcat acggcagaaa tcgacgagtt ttcttcatta
     5821 gtagagatgg ttttttcttg ttggctatgg gttttacagg aaagaaagct atttacttca
     5881 aacaaaaata cattgaagca ttcaacgaaa tggaagatgt tattcgcaag aatactgttc
     5941 ctcaaacaat tgaagatatg atgatctacc aactagaaga aatgaaagat gttaaaaaag
     6001 atgtttccat gcttaaagat actatgcgaa ttagtgggca acaagagttt gaaattaaac
     6061 aaaaaggaaa tataaaagtt atggaagttc tagggggtaa agaaagccga gcttatgaag
     6121 aaatcagcaa aaaagtattc tcaaaatttt ggtctgaatt taaacgtacc ttttcaatcc
     6181 caagatatgg cgagttacct cgtaagagat tcgatgatac tgtttcattt attgaaatgt
     6241 ggttaccaga aactgcgatc cgcatggaaa tcgatcaact gaacagacaa caaagacttt
     6301 tcggtgatga aaatgaatag agctgaagcg ctaagaatcg ggacggtaat tgctaatcgc
     6361 tggtggagac acaataaacc aatcatccta agccaacaac atattgacaa gcaaaaagca
     6421 tggcaacaaa taaaaaagtg actccgccgg caagcaaaga gtcacaaaga aaacacatca
     6481 taaggagatt ttagcatatg gaaaaagaac tttccactct agatcaatat ttgactgatc
     6541 ctagttgggg caaatcgaat atcaaggaaa caaataatcg aaaaatcaga cgaaatcttt
     6601 tgacggatga agaactagca tgtgatcaag acgatttggg aaattttgtg agtatttggg
     6661 atcatgtcta tcttatccat ttatcgagga agtccaaaaa cctgaatata tctatgtcat
     6721 cgaagatggc ttgattgatg cgctagaaga gtatgacaga gataacttga ttgatatctc
     6781 ttattacgga tcaggtaaga aatacattgc tgaaatggag gcagaatttg atgagtgaaa
     6841 acaaagggac aacgactttt gaaaaacttt ttagtcgcaa gttaaataaa atactcaaga
     6901 aaaaaggaaa ttttgattat ttatcttggg ctcacgcatg ggagattatg aaaaagaatg
     6961 atccacaggc aacggtaact attaatgagt ataaacacta cagagttgtt tctggaactc
     7021 atcaagactt tcttgttgag gaatataaac cttttcttat ggatgaaact gggacttatg
     7081 tatctgtctc agtaacggtt aaaggacaca cggaaaccga attatttcct gttttagatt
     7141 atcgaaacca accagttgtt aaaccaaatg caatgcaaat caataactca ttgaagcgat
     7201 gctttgtgaa agcattggct ctacacggac tgggattata tgtatttcaa ggggaagata
     7261 ttccaacacc acctagaatc gatacgaaga aattaaacat gctagagacg attctagaag
     7321 ctttcaatga gcagatgggt aaagatatga ccaaaacctt aatcgaatat gttaatgagc
     7381 agacagataa attagggctc ttagctgata acgttgaaac tattgaacag ttaagctatg
     7441 agcaatgtgc cttgatggag cgagcaatag cagctaagag aaaagaatta gataagaagt
     7501 gatatgagtg tttaaaccat taatcgattc atattcagcg gttctgaaaa agttcaaagg
     7561 aaaagacata ggtgcaacga tcaatgaaga agtgaacatt gatcgactaa agacgatgta
     7621 tgacggctac gatggcgatc gagtcattga aattcgtttt attgatccta gacgtttcac
     7681 tgtacagcaa cgaaacttca tctatgcgct cataggcgat attttcatcg atacaggcat
     7741 gccaacggac ttctggaagg aattcttcta cttccgtttc gaaggtgtca cagggcgcaa
     7801 aataagcctc aaagacgaat cgaatacaac cgtgagtgat gctaacgtct tagcaaatat
     7861 catcctagat tttatctttg aacatcatat tcctttcaaa gaaggctatg agattttacc
     7921 agcgaatcaa gagtattact tctacaaatg cattacaaaa agagtctgct gcatctgtgg
     7981 caaaacagga gctgatattg atcactttga caaagcttta ggaagacgaa agcgcaaaga
     8041 agttgatcat tcagagtaca catttgcagc actctgcaga atccatcaca cagagaaaca
     8101 caaaataggt gtgaccaatt tcaaaaataa gtatcaaatc aaaggaatca agttaagtca
     8161 tgaaacgatt aaaaagttaa ggataggagg ataaatttgg ctgagataag ttggatcaaa
     8221 cttaaaacta ctatgtttga cgatgaaaaa atacgattaa ttcaagctgt tcctgagtcg
     8281 gatgccatca tcgttatatg gattcgatta ctagttttag caggaaagac taacgacgat
     8341 ggtctaatat acatccagag gaacatgcct tataccgaag aaatgcttgc tacattgttt
     8401 ggcaaaaacg taaatacggt tcgcttagca ctaaccacat tggcaaattt caacatgatt
     8461 gatctaggca gtgatggact aattgccatc agtaattggg aaaaacatca aaatatcgag
     8521 gggatggata aagtaaggct aaaaaatgct gaaagaaacc gtaaatacag agaaaggaag
     8581 agacaggaac gtctcaaatt ggaaaatgac gttagcgtga cgtcacgtga cggtacagat
     8641 aaagatatag aagaagataa agatatagat aaagaagaaa agaaaggtaa gtattctaac
     8701 gaacacttac gccttgctaa aaagttgcaa agtaatttaa ctgaagattt tccaaaagaa
     8761 atgactaaag tagatatcga aaaatgggca gacacaatca ggttgatgga agaaagagat
     8821 aaagcatcta tagaagcgat tgagtatgtg atcaattggc tacctacaaa tgaattttgg
     8881 tttggaaata ttagaagtgc taagaaattg agagaaaaat ttgagaagct caaattcgaa
     8941 atcaaagcag ataagaagaa tcataaaaag caaagtcaaa aactacagta cagcaatcct
     9001 agtgaatatg acgacttgcc aatttaaaaa ggagatgcat cacatggaaa gcctagcaaa
     9061 tgctatggag aagctaataa gaagagtatt agtgcaaagc ggaaaatgtc cagaatgtag
     9121 cgaacctttg tatagttggc gagctaaaaa taaggatggt tcagaacgtt gtaaaccaac
     9181 atgcatgagt tgtggttata aagcgttacg tgtgaaagag gatatacaga ccgaacggat
     9241 atataacgac agcttaaaag cacgagcatt gagttttttt caaaatggtt cggtattaac
     9301 agataaaact ttgtttaaat gcaaaatgga gaattatcac gtagtggacc aagaaacgaa
     9361 aattgcttta gaaagagcta aaagctttgt aaatgatgtc ctactgaacc atcctgcaca
     9421 tttcattcta tcagggaaat caggaagcgg aaaaagccac ttgtcaatgg cgacagcttg
     9481 ggaaatactt gagcgctcaa attatgacaa gaaaatactt tttataagct atcaagagtt
     9541 attagagcaa ataaagttct cttataacaa tgctgaactg agaaaagaaa ttgaaggatc
     9601 gcttatagcc gatattaaaa caactgattt ggtggttttt gacgatattg gagctgaatt
     9661 aggtagtggg gtatcaaata gtaggcagtt tacaaacaac acgttaaaca cgctcttaga
     9721 agccagacag aacaaggcaa cgatcatcac aacaaactta tctggtcctg aactaagaga
     9781 agcctacggc gaaagaattg tttctaggat atttaagaat tcagaaggtt atgcgctgaa
     9841 attccaacaa acagcagaca agcgcataaa accagtgaaa ggtagtatcg catgaataaa
     9901 taccgtaata aaaaaactgt tcatcgaggt atcaagttcg attctatcgc agaagcagag
     9961 tactacgatc tagccttatg gcaagctgaa gcgaacggct ggaaagtaaa acttcaggaa
    10021 cgatttgagc tgatgccgaa atttgaacta gacggaaaga agtatcgcaa gatcgagtat
    10081 attcccgact ttacatttta taaaaacggc aagcttgtca aagtcataga tgttaaaggg
    10141 atgcagacaa aagactttaa gatcaaggca aaattgtttt gtcataaata tcaagtgcca
    10201 ttgattttag ctaaaaaata tcggaatacg ttcaaggaag aacggtttta acgaggtggt
    10261 ccatcatgac aacagaagaa gtgattcaaa tgcgtattcg aagccttcaa cgggagattg
    10321 acgatctgga acgaacaaag gcagtgatgg tcaatgaaac ggcgagaaag gcaatcgatt
    10381 tacacatagt gaatttaaga agggaaattc gtagattgga ggaatgagcg tggataagaa
    10441 agcagcaatg aaacgaatca ttgaactgac acattctgag aattggcaag aagacaaaga
    10501 aatagttgca gaagtccaaa aaatcggtaa atcaatgtgg actgaaaagc ctaaacggaa
    10561 aacgccgaga aaaattgcaa tctggcatgg tgatcgaatt ctagtaacag gtactgctga
    10621 acagttatct gaaattactg gtctgagcaa aaacatcatc tgggatagag ctaggagctt
    10681 atggattgat tcaaaaggac gacaatttag gtatgtggag gagaaataat ggatctcatt
    10741 acacaataca gtgatatcat cctcaagaaa atcatgatga agattcagaa agataaaaaa
    10801 tcaaaagaac gagcggaatt agtcaagttg gaaatggctg aaacaggagc aggagtgcga
    10861 agtagcaggc attggaaagc agcagcaaac attgaattct attacaacga aattcaaaaa
    10921 gggttcgatc agatgcgtga gctggatcgg caaacaaatt ggagcaagaa actataccaa
    10981 gatcgtttca agtttgtaga aaagtataga gagatactag acgaatacat ggaggaagcg
    11041 gaatgaacac cagacaccgc agagtagcaa aactaagaaa acaggaactg aatgtactaa
    11101 agacaaagtt tgaaaaagaa tatggaattt cagcagaaga aacatataaa gtggcaagtc
    11161 agtttgttgc tgatgcgagt gagactattc gtaagtttgg gatttcgata ttaaatgatg
    11221 atcgtaaatg ggaggcagaa agatgaaact aaaagacgga ttttacactg atgcttatgg
    11281 aattggtggt ttgatgatgg atctaccaac taagaatcct ataaagcaag aggaatcaga
    11341 aattaaagtc ggtgacatgg ttcgctgcga agcagaaggg ttcatctatc catttcgtgg
    11401 atatgtagag catctctata atcactcagc gatcattcgc attgaaaaca cgatggaatg
    11461 tgacaagcgg ttagcgaaaa gcaaagagaa tttagcagtg gtgagattgg tggatatgga
    11521 agttataaaa tcttaatttt gcttttttac aactatccta caacaatgag cgttattcca
    11581 caactggaag gagaagaggc aattgtgaac attttagaga atatagatat taagcaaaca
    11641 aggaaaaatg ctagacgatt actaaaaaga tacagaaatt tagaacgttt ggtcggacca
    11701 gtgaaaatag acttttccgt gatgactgtt accaaaaatt tgaaattcac aattgacagt
    11761 caaaacgaag aaatcattga agcgataagt actcgagatt cggttatcga agcattaaca
    11821 cggctaagta gaatccattt ccaggtactt tattatagtt attgttttcc taataagatg
    11881 tcaatgtatc aaataggaga aaaattagga tattccgata gaactatcga gagaatgaag
    11941 gcagtagctt tggttgaatt tgctgaggcg tataaatcag gagaactcat ttcacgtaca
    12001 aaataaaaaa agtcggattc ctccgactat gaataatatt tccgacataa gtattatatc
    12061 ataattgggg gaatcagagg atggtacttt tcgatgtaaa gaaatatgag acaccaagcg
    12121 cgaaagatgt tgatatggaa cgcacaaaac ataatgtcgc tgtgtttctt tcagcatatc
    12181 tatcagctag atgtagagta gggcaacctc gagaaccaaa agtgacagca tcttattcct
    12241 tggttccacc ttctacagct gatcatatat ttgaagcaga aagaatgctg atcgataaag
    12301 aagaagcaca ggaagaattt gagtatctgc ataaattgtt tgttcgaggc tattcagcga
    12361 tacagcatcc gcataagcct gatgtgactg aaaggcgcaa gaagatattc tatgatcgtt
    12421 atatcaatgg tctgcccatt tatgtaactg ctcaaaggaa taatactagc gaagaatcgg
    12481 ttaaagtaga atcaaacaga attatcatcc aatttgcttc atcgttagaa ctggttgctt
    12541 tcaagtagcc agtttttaca ctttttatac ccttttatta ccaatttggt ttccatttta
    12601 tacctttttt ataccaatca cttacctatt caacgttgta ttatgatagt gtcgaaagat
    12661 tagtgatagg tcttagacaa aataaaatgt aagggaggaa atctccctca tcgttttaaa
    12721 ttaagcctcg atagacagca gcggaaatat taagaataag gatgtgaact caactccttc
    12781 tgaattcttc gtatgctgct gtctattaaa ttatgtgttg gagggtaaga atatgaaatt
    12841 atcgattgaa ggtacttcag gagaaataaa agaaatcctc tcagctattt gtaatagccg
    12901 agagattagc aatttaatca atatagataa tttaaatgaa tctattgtta ctccaagttc
    12961 ccgagagaaa ttgcagaaat ctgatcagca aaaacaacta aaaatgggat attagtagtt
    13021 ctctcgccta tgatggtaac atctttcaga aagatagatt tgactaccaa actttgctca
    13081 tcatcttttt ctatatcatc aatttttttt gagcgaaatt ctgcaaaaga atccatcata
    13141 gcatcaataa gaggatttac ttttacttca gcatcaaagt ctataggagt tccgcaaatt
    13201 gttgctcctc cagtttgaat aataatatta ttgttagaat ttttagcgaa gagttcaata
    13261 tattcaatca tgtctgaacg gtaatcatca atttttgcca tttttttacc accttaaatt
    13321 atttcagcgg accactcgct gataaataaa attatacact tagtatttat tttcacaata
    13381 ttaatttatc gtaataactt ttgagtaaat agaacaaaaa acctgcacta gtttccgcta
    13441 gtacaggcag tgactatatc ggttgataat ctagcatata ttaaaaataa ttgcaagaaa
    13501 agaaatttat agtggtttat accaaattat caaagcaatg ttattttgtt gctgtctatt
    13561 gttttttaat tattcacacg ataactaaag gtgggtgaag agaaatgatt ccattaataa
    13621 tttcaatttt tgcgctctgt cttaatgtct atatgattgg atttaaaaat gggcaaaata
    13681 aaaaatagta gcagccaaga ataattttat agtgtcactg tggcggaaag ggtagacgct
    13741 aagcatgtgt gctaggtcaa tgcttcggca accatgcaag gttcgattcc ttgccagtga
    13801 ctttagtgga tatccaaggt aaaaggaacg gaagtgggaa tcaggcatga ttcggtagga
    13861 taactgcgag ggcatattaa gttgaccact taagtaaaat aattagggag atgcacctag
    13921 aaatagagtc ggtcgctcta tagggtagtc atcaaattag actttgctat ggttagaccc
    13981 taagccagta aagttgtggc ggtgaaccct tgccgctttg acgtgaagta tctgtggtga
    14041 tacgtctgac ttttaatcag aaggtgcagg ttcgactcct gtcacgtcaa ttagcaaccg
    14101 agggtggtat gaactcgtgt ggtgcgagcc ctagggagga acaggataac cgcctgtgtg
    14161 taggttgcta gtacatatta gatcactcgt tgagtggtct ttttattttg caaaaaggag
    14221 gtaacaacaa tgtatagacc acaatactta gaacagaagc atgaagtaat cactgtgcaa
    14281 aacggtaacg gtgagatagt acgaaagtat agaagaccaa taaagagcaa tacatataaa
    14341 cgaaaggaaa gcaatgaagt tattccattg tatggcaaaa gaatagctaa gtattaaata
    14401 agattgcgaa aggagatggg acatgaccga ggaattctat agatggttat tacagttgat
    14461 aagagaagat tgtttggtta agttctatca gtctcctaaa tggcgcaggc ttagagagaa
    14521 agcgatgaaa cgagatcact atgaatgcca agagtgtaga agactaggta agtatcatag
    14581 agtagagaac gttcatcata taaaggaagt caaggataga cctgacttag ctttagattt
    14641 agataatctt atttgtttat gtgttgaaca tcataatgaa gttcatggca gatatcttac
    14701 agcattagat aaacaagaga agaagataga aagctttgct aacttcgatg caagtgaaag
    14761 gtggtaagtg catgatcatc aatgacaatg gcagagagta tgacacagaa aagattgaag
    14821 agtattcatc ttatactcaa ggattaatta aacgtttgat atacgttcgc tatgtaggta
    14881 ttagggatct gttatcagat aactgttgca gtaaatacaa agtgaatcaa gtaagagaag
    14941 cgttgaataa agataataac gttgaaagaa taaaaaatat ttttggatat agcattgaag
    15001 agattaatta ttacattgac ttcgctgaag ctttcattcc gatggtgaga taaccccccc
    15061 ttaaaataaa tcgcaaattt tttgggggtg atgaaacgga gggggctgtc aggaaaagag
    15121 attttttcga actttatcat gaaaggaggg ctaaaatgtt taaaaacgaa ttgtctcaaa
    15181 atcgctacag agaaaaatta cgccgctctt taataagcca attggaaagt cagaaaacaa
    15241 atattgagcc attcttagat aatgttgatc gttatatcag tttatgggaa acggcgatat
    15301 cactggaaga agatatatcc gagaacggca ttagactgga gaatggtaaa aagaatgaat
    15361 cagtagcgtt gcttgtttct gtcaacaaac aaatgggatt gatgttggat aaacttgcca
    15421 ttactcctga attggtaggt gaagcaaatg aatcaattcc tgagttataa gcatattgaa
    15481 aattggttca aagctataga agaaggcact atcaaggtat gcaaagagca attattgcta
    15541 aaaaattatc tagaagaaag agtctttact agagaagata tttacttcga taagcagatg
    15601 gtagaggatt caatcaatat accagcacaa tactttccat tcgaattaat tccgtgggaa
    15661 aaatttctac aatgttttat ttatggtgtt cgatggaaaa aagataaaac actagtgttc
    15721 aatagatatc tttcattaat gggacgtggt aatggtaaaa ctggttttgc ttcttggaac
    15781 aacttctttc tactaaccgc taaacacggt attaaaaatt atgatattga tatctatgcc
    15841 aataatgaaa gccaagcaaa gactagtttt gatgatgtat ttaaagtaat taaagatcat
    15901 cctgatttag ataaaaaagt atttaaagct acgaaggaag ttattcaaaa tatcgctaca
    15961 aacagcaaac ttcgttataa cacggcaaat gctagaacaa aagatgggaa gcgaccaggt
    16021 gcaaaccgct ttgatgaaat tcacgaaaat gaagattatt caatgataaa tgtggctact
    16081 tctggtggtg gtaaaattcg agattataga gaattttatg atacaactaa tggtcatgtt
    16141 cgtggtggtc cgcttgatga cattatagaa gaatcaaaaa tgattctttc tggagaactt
    16201 ggaattgaca aggatggagc agaattttct agtttgtttc catttatttg tcgcttggat
    16261 aacgataatg aagttgatga tcccgacatg tgggaaaaag cttgtccaac tattaattac
    16321 aatgcagatt taaaacggaa aatgtttcaa gaatactctc aaatgcaacg taatgctggt
    16381 ttaagactta cgttcatgac caaacgaatg aacagaccta tggaagatac acgatttgct
    16441 gttgcttcat atgatgatgt tctgcatacg aaagaaaaag aatttcctga aaaaatggat
    16501 gaagtgatag gaacagtcga ttttgctgat agacgagatt ttgccagcgt tgggttgcta
    16561 ggaaaatacg ataaagatgt ttattttaca caacatactt ttatccacga atcagccctt
    16621 cgattacaaa acatcaaacg agaggttata gatatttcta tagatcaagg aaaatcacag
    16681 atcgttcatg gaaaaaatat agaagctgat tatattgtag gttggtttct tgaaatgagt
    16741 aataaatatt atattaaaaa aatcgctatg gatatgtacc gtgcaaaaat attgaagccc
    16801 gctttagaag aagcaggttt tactgtggaa attgttcgaa gcggatctgt tacacatggt
    16861 atgttaaaag atctggttga tgaccttttt attaatcaac gtttattttt tggtgacgat
    16921 gcgattatgc gttggtattg catgaatgta tatgaagagc atatttctaa tggaaatata
    16981 cgctatgaaa aaatagaacc tgaaactaga aaaacggatg gctttttttc attccttcat
    17041 ggtttgaatt ttttagatga tatttatgat tctgctcctg taacagtcac aaatagctca
    17101 gtagaaaata caggaactgg atttactcct ctagtattct aacttgaaag gaggtgagaa
    17161 agtggggatt tttcaaaagg cggtaggata cttcacaaaa aaagcaacgg ttcctttaga
    17221 agaatacttt tgtaaattgc aagttgattt tgtgtatcga aaatttgcga ttgaaacttg
    17281 tattgatttg attgcaaatg cgatgagtaa agcggaattc aagtcatatg aagatggaaa
    17341 aaataaaaag aatgatcttt actataggct gaatgtagct cctaataaga aaaataatgc
    17401 aacagaattt agaaaaaaac tgatcaggag attaatattc tacaatgaag tattgatcgt
    17461 ttctccgtct aataattcta gcgaaatatt tattgcggat agttgggatg tcacagaata
    17521 tgcattgaaa gatgatgtgt tttctcaagt gcaaattaac aacatagtcc ttgatagaga
    17581 atttctagaa agtgatgtta tctatataaa atacgcagat caacaaatta ggcaactagt
    17641 cgatgcgtat tatcaagcgt atgggaaact catttctagt gccatgaatg tttacaagcg
    17701 ctctaacgct cgtagatacg tactgaaagg gaatttattc cgaccgcaag acaatacaac
    17761 acaagatcaa atcaataaaa tgatgacatc acaatttaag gattttatgg aagctgataa
    17821 tgcaggtgcg gtatttcaat tacaaaatga gtacacatta gaagatttca gcggaaactt
    17881 ccaaagcaat tcaagagata taaaaaactt aatagacgac atctttgaga tgacagcagc
    17941 agcgtttcac gttccgaaaa acctactaaa gggagacatg agtgggttat cggatcaagt
    18001 ggacgctttt ttaatgttcg aaatcatacc gattgctgaa cttattcagg atgcgtttaa
    18061 cgctagtctc tatgaagtag aagaatactt gtcagggaat tttgtacgtg tggatacaac
    18121 tatgatcaag attactagct tcaaagattt ggttgacgct attgatgtag gcattagaaa
    18181 tggagtattt acaatcaacg aaggaagaga acgcgttgga aatgatcgct ctgataaggc
    18241 gatggcagat gaaatattta taactaaaaa caatcaacaa gtatcgaaag gaggtgaggc
    18301 gaatgacgac aatgaaaaca tttctagcag taaagaatga aggcgcagta ccgcaaattt
    18361 ttattcaggg atttattggt tctagttggt tctttgaagg gaatactgac aagggaatca
    18421 aaaatatttt ggatagtcta ggtgatcaag aagaaattga agtagtaatt aattcaaacg
    18481 gtggagacgt atttcaaggg attgctattg ggaacttact taagtcaaat aaagcaaaag
    18541 ttaacgttgt gattaacggc ttagccgcta gtgctgcttc aattatcgca atggctggcg
    18601 atactataaa aatctacaac aatgcacaat tgatgattca ccgcgcttcc acatacggag
    18661 aaggaaatgt cgatgacttc cgtacgattg ctgaccaact ggaatcaatt gataaatcgg
    18721 taaaggcttc atataaaaca cgattcaatg gcacagatga agcattgcaa gaacttcttg
    18781 aaaaagaatc gtttatggat gcagaaacag ctttgagtta tggattggtc gatgaaatta
    18841 tcgatgcaga aaatagctca ggtactgaag ctaaaaaaga acaaagcgtt gaagaaattt
    18901 tgaatgacgt taaagaaaaa agagcagaaa aaattgctgc atttacagca gcattaaata
    18961 aaacatttgg acaaggagat gtaaaataat gacagttaaa aatttaaaag gtgtaacagc
    19021 tgcaagcgac caattgatga aagcttttaa agatggtaac gaagaatctt ttagcgcagc
    19081 tatggtaagc ttatctaagg aaattcagga taaaatttta gaagaagcaa cagcaaaaaa
    19141 tcaagatcaa ttagtattaa tgaaccgtgg tcagcgtgta ttaactacac aagaaacaaa
    19201 attctataac gaagtagtga aaaacgaagg ttttgcaggg gtcgaagaat tagtgccagc
    19261 tactgtattt gaacgtgtat ttgaagattt agaacaatct catccactat tgcaaaaaat
    19321 tacttttgtt aacacaactg gtgtaacaga atggattgtg tcacgtggag tcaatccagc
    19381 atggtggggt aaactttgcg aagctgttaa aaaagtttta gataatggct ttgatgtaat
    19441 taacatgaag cagttcaagc tatcaggtta tattcctgta tgtaaggcaa tgcttgattt
    19501 aggtccagta tggttagatc gttatgtccg tactgtttta gtagaatcat tgagaattgc
    19561 attagaacaa gcaattgttg atggtactgg taaagatatg ccagtcggaa tgatgcgtga
    19621 catgagcaaa caaactagcg gagaatatgc tgaaaaaaaa gcagaaccta ttacagcttt
    19681 agatgctgta actatgggcg gtttgatggc gcgactatca aaattcaata tcgaaggtgt
    19741 gaatgatccg atttatcgta atgtgaatcc ttctgatgtg gtcctaattg tgaatccaac
    19801 tgattactgg tctaaagtat tcccagctaa gactgtacta actgctaatg gagaatacgt
    19861 acaagtattg ccagtaccag tttcagattt gcagtcaacg gctgtgccag aaggaaaagc
    19921 agttattggg gtagcctcag attacttcat gggtgtagga tctacactaa aaattgaagc
    19981 ttcagatgaa taccattttg ttgaagacga acgcatttat ctagctaaac aatatgcaaa
    20041 cggtcaacct aaacgtaacg atagtttcat tgtattagat attagcgctt tgggaactac
    20101 tactacaact acaaaaccaa caaccacaac aactacaaca caagcgtagg tgatcagaat
    20161 gaagtatatt ctttgtcagc tggcaatcaa tcggtttaaa tgggagcttg aagtttgttt
    20221 aactaatctg aagaaactag gaatcaaaga tatcgtattg cttttcagca gacacgatga
    20281 tcagattcct attttttttg agaaggaata tggtgttgaa gttcatgtgt acgatgatct
    20341 gcgggacgac aaagagtata ttccttcgat taaaccatat ttatggtgga aatatttaga
    20401 agaagatcat tcgcgtgagg acgaccgata tttctatatc gattcggatg tcattttcaa
    20461 taaaagaatt aatttgcgca aattgccttc taaagatgat gtttggtatt gtagcgactg
    20521 ctgtagttat ctaagtcttg attatattag aagctgtgaa aacggagaaa atattctaaa
    20581 agatatggca aacattgtaa atgttacagt agaatctttg gaaactataa acactaattc
    20641 aggaggcgca cagtgggtta ttaaccgtcc taaagcgaat tattggaaaa aggtttatct
    20701 ggattctaat cggctatatc gctaccttag agggcaaaaa acaaatatac aaatctggac
    20761 agccgagatg tgggcacagc tttggaacat gatgtatttc aatattggtc ctaaagttca
    20821 cgaggaatta gacttttgtt ttgctactga tccaatagaa aaagttaaag aagtaaaaat
    20881 cttacacaat gctggagtaa caacaaacga tgaagattta tttttcaaag ggagatacgt
    20941 gacttctacg ccttttgatg aagatttatc atttgtaaac aagaaaaaat gctcttacgc
    21001 atatgttaaa gcaattaagg cggtggttag atgacgcctg aacaagtgac tgaagaattg
    21061 ctaatagctg tgaaggataa tatttacgtt acctggaacg aagaagatga gtcaattaaa
    21121 aagatgatag ctaaaaatgc tgtttatctt caaagtaaag tgagtacaac actttctttt
    21181 tctcctgaaa gcttagaata cggattgcta atcgaaagat gtagatacga ctggaatcgt
    21241 gctttagatg agtttgaaca aaatttcgct agtgagttat taggtttcat tcaacattat
    21301 gcgctacaag aatatattgc aggtgatgtg aatggcgaat aatcgtagac tcgaagaaac
    21361 attcaacgat ggttggttaa agattttgac gcaaactacc aaaagaaatg aactaggaaa
    21421 aaagattggt gtagaagata cagaaatcac ttctttaaaa tttagaaatc tttccatgag
    21481 agatagtgat ataacagcta tggatgcgat gggatcgaaa ttaactaaga aagtaaagac
    21541 tccatttcat ccaatcgcca agaaatttaa taaagatcaa tattttatcg taatcgatag
    21601 tatgcgttac aacgttatct atgccgatta cgataatttt tatatctatt tttatcttga
    21661 aagtgtgggt gaatatggtg attgataatt ctaaagaaaa agaacgttta aataagcaaa
    21721 tttctgctat caaaacttcc ttagaagagc attttggcct caaactcttt caagactccg
    21781 taggcgagga tgagctacct gatgatttta attacttcat tctcgaaaca ggagaaatag
    21841 aaatgatcac tgagccaaaa tatagcgtgg gtcaaaatct atatctaact ttctattcag
    21901 aaaatagaga agatttaaca ggagactcac tagatattat ttcattgatt caaaatcgtt
    21961 cgattcgttt tcagagaatg gatcccaatc atttaaaact agagaaccaa gatcgctata
    22021 tcgatcaatt ggtatttacg tttagacgat tattgaagag tgattgtcat ggctaaaaat
    22081 agttgggagc taaaaataaa tggacatgat gaacttcttg tgcggatgga acgctattca
    22141 agcgagagcg aacgactgat taacgaagca ttgaaatcaa aaggttcggc tattgcagtg
    22201 gataggatta cagaaaaaat tcctgtttct gaagcagatt taagaagagg gcaccaacac
    22261 gcaaaaaata gtcgtccact taagactcaa tacattaatt tgggtttcat cattagacct
    22321 acaagaaaat ttgagtattt aaaatatcct gatttgggga taggtacttc taaaagaaat
    22381 cagccggacg aatttatgag aagaggatta ggtcttgcac ttgatccaat tacagaactt
    22441 ctgattcgtc aattcgataa attaaataaa tagggggaac aacaatggct aaaacaaaaa
    22501 ctgtagtaac aacgttcgat aacataagta tcaaacgaat tgcttttaat tttaagaacg
    22561 caggaaatgc aatcgcaacg aattgtaacg gacaattaga tggcgaaaca gaaatgcaaa
    22621 cggtggttaa aaaatgtgga gcgacagaag taaaatcaaa atctaaacca atcaatatga
    22681 cggtaacaat tactgcacat gtaccgatgg aagtttatcg acgtttcaat gggttgaaac
    22741 aagatggacg tattaaacca ggcatttact cttacggtcc tgattccgta ggcgaagatt
    22801 tctcacttgc tgcagagatc gtggatgact tcgaagaaaa tagaaagtta gttggtatgt
    22861 tagcatgcac ttcgaataca ggattaacat tctctattga aaatggtgcg gatgaagtag
    22921 ctgcgttaga actagaagca aaagttatgc aagatgaatt tggtaaattt tatcatgaag
    22981 caattgttgc agaacttgaa gaagacttaa cagatcaatg gatgacgaat ctatctgctg
    23041 atgtgattaa aaaaacttca gttgtgacaa ctacggccac tcaatcacag taaaaaaaac
    23101 ggaggtagcg aaatgaacga agattactca aaaattgaac taaacgatgg aacaattttg
    23161 aatttagaac ctaaactgaa tatcaagaaa ttattgatga tcaatagaga ttttaacaca
    23221 gacgagtttg caaaaatgac tgtgggaaaa ggatccatgg atatttctgt tattcaaggt
    23281 gcgaaggctg tgtatattgc ttaccgccaa gcgaacatga ctgattatat ttcattcgat
    23341 gaatttatcg ataaatggga ttttgatatg gctactgcca gctatattta tcaattgatg
    23401 atgttcaaac aagcacgcga tgcttatcaa aaagaatttg aaaaagcaaa taaggaaaaa
    23461 aagcttcaaa agtaaaaatg ccaaagctct tagttgaaac gtgggtcgat gtctattcga
    23521 tgttgaccga cgttttttct atgccttcag atttggtttt aagcgatatc tgtttagatg
    23581 acattttgca aatggcttac aacaagagtg cttatgaagg atggaaaaac tatgcaataa
    23641 accaatccca gaaaaactaa agaaaggagg taaaaaatgg ctaaaaagag aacagaagca
    23701 gaagtaactt tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct
    23761 gaattaacta aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt
    23821 tctgaatcag acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa
    23881 agtcaaaaag ttgaagtaac tagtcaacgt ttagccaatg ccaaaaaata ttatggagaa
    23941 aattccaccg aagttcagaa acttgaaaga gaactgatta atcaacaaac agctcagcaa
    24001 aggttatcta atgatataga taaaacgagt aaggcattgg ctcaagcaaa aggcgaaata
    24061 cagacgtacg agtctacaat gcaacagttg gatagtgaac aaaaaaatgt tcaagctagt
    24121 gcttctctga ttgaatccga atacaaaaaa tggcaagtaa ctgctggtca atcagcttct
    24181 gaatccgaga aattagcgaa agcccaagaa tatgtttctc aacaatctga aaatgcagag
    24241 aaaacgatag atatcctgag acgacagtta gaagctacac agtctgagtt tggcgctaca
    24301 tccacagaag caatgcagat ggaggcgaag cttaatgatg ctgaacgtga atttgaagag
    24361 ttaggacaag ctgctaaaaa tgtagataca actaacttgg acgatatcgg aagcaaaata
    24421 gatatgaata atttaatgga agcttctgac gttttaagcg acattggcga taagcttaca
    24481 gaattaggga aacaagcagt ggactctgct aacagtgtag gtagttccca gagtaaaata
    24541 caagctaatt ttggtttgac taaacaagag gctgaagaat taacgaatgt agccagagac
    24601 atttattata aaggttttgg agaatcgtta gatcagtcca cagatgcatt gattttggta
    24661 aagcgtaatt taggcgattt aaataatcaa gatttacaaa atattacgga acaagctatg
    24721 gtcctagaaa acaccatggg cgctgatatg gatgaaacgt tacgtggtgt aaatggctta
    24781 atggtcaact tcggattgag cgctcaagat gcaatggatt taatggtttc gggtactcaa
    24841 aacggtttag ataaaacgca cgaattaggc gacaatatgg cagaatatag ccaattatgg
    24901 agtcaaatgg gatattcagc tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg
    24961 ggtgcttata accttgataa agtcaatgac ttagttaagg aaatgggaat atcgttaaca
    25021 gatggtcgat ttgagcaaaa catggatatg tttagtgaaa gtactagaaa agcttttgaa
    25081 gagtggaaaa atggcggagg aacacaaaaa gacgttatta attccatgat tcaagatttt
    25141 agcaatatgg atggtcaata cgaccaatta aataaagctt ctacaatttg gtctgcactt
    25201 ggcgaagata acgcgatgaa agttgtccaa tctttgactg atgttaacca tacatttgat
    25261 gatgttagtg gatctgcaca aaaaatgaat gaagactcta ctactccgtt acaagaatta
    25321 aacggaaaaa tagctgaatt aaaggattca ttagctccta taggcaacac aatcatagat
    25381 gcactcgaac cagtaattga ttttctagga aagatggctg atgcgtttaa taatcttcca
    25441 caaccagtac aggattatgc cgtagcgatt ggcggattga ctgctgcatt tactttatta
    25501 atgccaataa tagttggctt catggctcta ggtggtccta ctacattaat aataggagca
    25561 gttattactg ctattgctgg agttatagca attataaaaa actggggtgc aattactgac
    25621 tggtttagtg gtttatggaa aaaatttact gattggttgg gtgatacttg ggaaagtata
    25681 aaagacggag cctcatcagt ttgggatggg gttaaagaaa cctggtctgg atttgtagat
    25741 tgggttcaag atatttggca aggcgtttct gattggtttg gagagttatg gagcggatta
    25801 gttgaaggag cttccaacat ctggcaagga gtccaagaga cttggcaaac attcattgat
    25861 tgggtttcaa atatttggaa cggagtcaaa gaagtatggt cgattatttg ggcagacatt
    25921 gtaggaattg ttcaaatacc atggacatta ataacgtcat tgattcaagc tggtattaat
    25981 attatcgtgg gtatttttga tgtagctgga cagttattag gcgcagcttg gcaagctgtt
    26041 tggacaccta tttctgattt ccttaaaaat acttgggata ctatgacaca atggataagc
    26101 atcgcttgga atggaattgt aactacattc catactatat ttgatccagt agtggcatgg
    26161 tggaatggta tatggacatc tattagtact acggcttcaa atatttggaa ctcaattagt
    26221 gcaacagctt ctagtatttg gaatagtatc aagaatacaa tcactagctt ggtacaagca
    26281 gctgctacag taattcaaaa tatttggtca actgtatcta gttggttagg tggaatttgg
    26341 aattcaatca gctctacagc atcaaatatc tggagtagcg tgactagcag tataagcaat
    26401 gctataaacg cagctaaaag tgccattcaa agtgtttgga atagtatatc ttcgtggatc
    26461 agcggaattt ggaacggtat caaaaacact gctttgaatc tttggaatgg aattacaagc
    26521 actattagct ctaaagtaaa cgatggaaaa aatgcaattt caagcggttg gtccaatcta
    26581 acaggtattg tttccgacat attcaataat gttaaaagca cgatagctaa tatatgggaa
    26641 ggtatcaaaa agactgttag cgctccgatt gattggatta gagataaaat cagtagtgtc
    26701 tttgataatt tgaatatttc gataccacat attccgttac cacattttaa attgagcgga
    26761 gaattcaatc cattgaaggg gaaaatccca acattgggtg ttgattggta tgcgaaaggt
    26821 agtgtgttta attctccaaa tattatcggt gtcggtgaag caggacctga agcagtttta
    26881 cctttgaaaa gatctgtgct gcaagaaatt ggggatcgta tcttgagtag cacctcagtt
    26941 tcatctaggg cacaaacgat tcaacctgtg aacaattacg aattcaattt cacaattgat
    27001 ggtaacgcag atgaggttac tatgaagcaa acaactcaac aaatcattga tagcattaca
    27061 aaagttcaaa atgataatgc ttcggcatgg cgttaaacag gagagtattt ctcctgtttt
    27121 tttagtttta aaaaggatgt gaaaaaatga ctgattgtat acattctata atcgatggat
    27181 ttcctgatta tttgcataaa ttggctttag cggaaagacc aaccatacct tctccaaaaa
    27241 gacagagagt tgaaacttct gttttaggac ggctaggtgg cttagtacaa gattactcgt
    27301 ttgaagacat gtcgtttaca ttgcactata actatttaga agatgtggaa gaccatcaag
    27361 cattcaagca atcgttttat atcatgcgtc attggttaaa ctatgcaaag aaattagaat
    27421 tctctgatga tcccaacgtc tattatgtta tccagactat cgatattggg gatgcagaaa
    27481 acgatattgt tgaatgggga gagttcgatg taaatatcac tgcgaaacca ttcgcaagag
    27541 ttcaagaaga tgtacctata accgtagata aaccacagtc atttaacttg ctgaataata
    27601 gtttagaaga aagttttcca aagattatca tcactccttc agctacttca tgccaattca
    27661 ccttaaatga ttatgtgttt agttttgaag gcttagtagt gggaactgac atagtcattg
    27721 atagtgattt gatgctttgc tacgaagagc aatcggacgg agatatttta gatcggtcca
    27781 acaaaatgaa gaccatgcaa tatccaacgt tgcaagtgga tattaatcat tttaattgta
    27841 ctggtttgag caaaatacaa atttatcgta atgggttaag gtaggtgaaa tagatgatcg
    27901 ataatttact aactatttac gataaaaatg acgcgaataa tttagctgaa catttatatg
    27961 atacgcaagg tttaggcgct ttgtcagact ggttaacagc tactgttagc aataaactaa
    28021 acggagccga gatatttcag ggtacttatt caataaacgg aactaatgca gatttgattg
    28081 tagaaggacg tattattcag tgttatgtag atgaaaatcg agcaaaacag cgtctacgga
    28141 tttattatgc aaaaacttct gtaataggca atacgataga agtaaaagct gaacctattt
    28201 tcaatgatat aagaaaatcg gtgttgaata aatatgacag cggaacagaa aaaatcactg
    28261 ctactcaggc atggcaaaac gcaaaagttt tagcgaaacc agctatccct tcgcagtttt
    28321 ctttctcgtc attagtagat acgcttgcta atgtgaagat agaaaaggcg aattttttag
    28381 aattctttgg tggaaaagag ggatctattc tagatcgatt tcatggtgag tttctaaaag
    28441 ataataacac attacgtcat gaaaaaagtc taggtacgga tcataaaatc aaagcgattt
    28501 atactaaaaa cttaactggt cttgacttag agatagatgc tcaaagcgtt ttagttggag
    28561 tttatccatt cattagcagt tcttcagaag gagaagacga gatcactcta ccagaagaag
    28621 ttattttcac ggattacgtg gatgattatc ctgctggata tgtttctttt gttgatttta
    28681 aagacaaagc gactgatgta gccacattaa gggaagttgc taaagactgg ttgaaaacaa
    28741 acatagataa acaaaaacca caagtgagtg gttcgattga attagtacca ttgaggcatc
    28801 aaagaggcta tgaaaaattt gttgatctag aaaaagtttc gatgggtgac ggagtagatg
    28861 tgtatcatcc acagttaaaa gtgaatatgt cagcgagaat cgtggaatat acgtttaatg
    28921 ttttaactaa ttcatacgat aaattagttg taggaaacgt caaaacaaac ttcttagaaa
    28981 atacagagaa taatgtcagc aatttgatta atgatgccat tgatcaattg aaaaatgttg
    29041 gcgaaatcag tgatttaatc aatgatattg tagatcatca aactgatatg attactggtc
    29101 aaaatggtgg ttatgtttta ttagatccta aagaagcgcc tagtcgtatt ttgattatgg
    29161 acacaccaga taagaatacc gcaaggaatg ttttacaaat caacaatgct ggtattggtt
    29221 tttctaaaac tggcattaat ggaacatatg aaacggcatg gacgttagat ggcggattca
    29281 atgcctcgtt tattacggct ggtgaaatag taggaattac tattagaggt actacattaa
    29341 ttagtgatgg tgctgattat agaacaagta ttgctaatgg caaaatgact tggtactcaa
    29401 aaaaagttaa caaagatatt atggagctag aagcacgtga ttatgtaagt gctgatgccg
    29461 gtattgtatc atacaccatg aaaactggtg gtggtttcat gattagaaat ccacagggta
    29521 acttggtttt tagtacgtgg gataatggta ataacagacc gtttctatct tttggtgcgc
    29581 ccaatttcag gtatagcaat gctagttatg taacttctgg cgacggtagt tctttaagca
    29641 ttaatggtag tgcgggtaac tcatgggaat ttaaggtagc tggtaggact atgaaattta
    29701 ctagtgatgg tatgctaacg ttaccaggtt gtttttttgg ttcatgggaa gatgggaaac
    29761 ttgctaggtt tgaacaatca acggtacaag tatataaaga ttttactgtt agaggtacta
    29821 aaaactcaac tgtaccaaca gaacattatg gacaacgact attgaacgct tatgaaactc
    29881 cagaatatta tttcgctgat tatggggaag ccgttacagg tgacgatggt aaagttcgtg
    29941 ttgatattga ccccatgttt gctgagacag taaatctaag tcggtatatg acacatgtga
    30001 cacctacaga actagttttg tgtgctgtta ctcatgaaga tattgaccat ttcatcattg
    30061 aaactagtaa gccaaacgta ttagttagat ggaatttagt ggcacaccgt ctagggtatg
    30121 aagatattag attaaaagag gatacagcat atgatagcac agtgcttgac caaaaacgtt
    30181 tttaaaacga agacaaggag gtatataaat ggctagcagt ttatataatt tggctttaga
    30241 tttcagcaaa gaattaaact acaccaaagc tattatggct cgtcagggtg ataaagggat
    30301 tacggtgacg gttaaaccat atttaaatgg cttgcagatg gatacgagtg gcggaacatt
    30361 tactttaaaa ggaacaacac catctaaccg ttacgtagat aatgttgcaa ctagcgtaac
    30421 tagtgaagaa gtcacgtttt ctcttgatgg cacatttatg agtgaagcag gatattataa
    30481 acactgctac gtagaatata gaaaagacaa tcaaattcta acaacgcaag atatcatttt
    30541 tttctcacta ggagtgtctg acatttcgca aggtcaagcc gatgaatatg tttcgcaatt
    30601 agaagagttg attcgaaagt ataatgaaac ttttgatgct tttatggctg aaactaaagg
    30661 tagagtggat agcttaaatc aacagattac tgatttaact ggtcaagcta aaacgctaca
    30721 agacaagtta gatgctctga aagaagaaat ttctaagtta ggtaacttac aagtgatgta
    30781 cagtaacagc attgatttcg ggggctatga ttattcgggg aatccgaatt tgatggctaa
    30841 tataaacgct gatagcttct cgcaaggtag tggtgcctta tctgttgtag atgatggtga
    30901 cgaggtagtg attacgcttg atccaaacca taaattagag gtattaaaac cgaaaagtca
    30961 accagcccta ttaacaggca aaacatatac cgtgagtgta gaaattatgt tagaaggtga
    31021 tttcactgga gaccctagca agataggcct aagatatatt aaaatgccta actgggtatc
    31081 agagctatat acgcgtaata cattaactgc tactaagggt gtatggcaaa aactaactgg
    31141 caccgttaaa attactgctg cgagtgataa cgctgaaagc tggcttataa tgctacaaaa
    31201 taaagacgct aataacagcc tatccggcaa actacgtttg agacacgcta aacttgaaga
    31261 aggctctaca gctacaccat atcagcctaa cttattggca gaaccttata atatgtgtcg
    31321 cgaatatcct aacgaaaata ttgccgatcc taaagttaag ttcccaatca aatctggcga
    31381 ccaccaaata tatcaaggtt acatggaaga agatcttatg ataggtcaaa cgtatactat
    31441 cacacttaaa ggaacaaaac ccgcaagtca aacctttgta gcgtataatc attggactgt
    31501 tcgtttagga gaactaaagc cagttgatgg gttgacagac gtatggtctc taacattcac
    31561 accaacgaat gttgcggcga tgcctaaact ttttcgtgtt tatcaatatc cacaatcaac
    31621 agtaggcgca tgccaaattg actggctcaa gattgaaaaa ggcaacacac gaaccccgaa
    31681 tattagtgag tataaatatc gtggtactgg tatgcgtgat tcaaataacc caaaagacta
    31741 tgtttgggat ctagcaccag aatatgtcga agataatttg gccacagata ttaaaatttc
    31801 tgaaattact ggtaaagcaa acaattatac cgatgggaaa gtatcggaga ttaattcgca
    31861 gttgactgct tcaattaatg aagtagacac cacagctaag gatgctcaaa caaaagcgaa
    31921 tgctaatgcg actgctatag atgaacgcat taatgataca gctactaccg cattttatgg
    31981 cgcacaaggt gaagtctcta acaaaacgaa agtagcggag tatggagtag gaacagggta
    32041 tactactaca gctgtaggag aaacacattt cgaacgtcaa tctaacggat acgttaaatg
    32101 cttaaaagct ggtaagtatt caattagtgc gcaaatacgt gtgcaattgg gcgggaaata
    32161 tgcttcatgg ttatatactg atttatataa agatggaact tctgttgata atttagtatc
    32221 ttatggggtc gacgccttgc aaaatagatt tgcagctagc ggaaacattg taactgattt
    32281 agaagtaaac gatgtactaa atatgcgtac tgaaatcggc gttgcagatg gaattttaca
    32341 atttacatct tgccgtactt tagtcttgac tagactatct gattaataca atatttataa
    32401 ttttgctatc aacacgctca aaggagggtg ttttttattt tgcaatgaaa ggaggctagt
    32461 tggttgaaag acgaagcaat acaagacgtg gtagaacgct tagtgcgtat tgaaacgaaa
    32521 ctggataatt acgaattatt acgcgaaaaa gcggaaagtg caaaagatag agcggatcag
    32581 gcatattcta ttgcgcttaa taatgcggaa gatatcaaag aaatgaaagc caataataaa
    32641 tggtcgtggg gttacatgat cggtttaggc gttacgatca ttggctattt cttgactaaa
    32701 ttgtaaagga ggtgagaaga aatgatttta cccgataagt attatcaagt cattaaatgg
    32761 gcagttttaa cagtattacc agctgcttct gtgttagtag ccacgttagg gaaagcgtat
    32821 ggatggaatg gaacagatat gacagtactc actatcaatg cagtagcaac atttttaggt
    32881 gttatcactg gtgtgtcggc ttataatttg aaaaaatagg aggaaacaaa tgaaaaagaa
    32941 aattactatt actgcgatga gcctattaac ggctcttttt ttattgccaa ttaatgggtt
    33001 tgcctatact atcaacaatg aatttaattt gggcgcaaat gaaggtagct cacaagtagc
    33061 aaataatcag tacattttac tgcatgaaac ggctaatgaa acagcaacag gacgcaatga
    33121 agcgcagtat atgcaacgtt catggactag tgcttacact gcttacattg tgggtgatgg
    33181 cggaattgtt taccaagttg gacaacctgg ttatgtacag tacggtgctg gttcgtatgc
    33241 taatgccaac agtcctgtgc agattgagtt acaacacaca cataataaag caacttttga
    33301 aaagaactat aaagcatacg ttgaattggc gagagattcc gctaagaaat acggtattcc
    33361 gcttacattg gacacgcctt ataaccaacc aggaatcaaa tcacatttat gggtaacaca
    33421 aaacatctgg ggcgatcata cagatcctta tggttatctt tctgaaatgg gcgtaagtaa
    33481 agaaaaatta gcatatgatt tagctcatgg atttaccgat gaaaatccaa caacttctga
    33541 aaacaagcct gtcattgatc caacacgagc tggtgcagct aatcctacac tgacagatgg
    33601 aacaaactac gctcatattg atcagtttgg ggaaattgaa aatgcaaact tgcatgtagc
    33661 tggatggcat attgctaact ataaatacga gtatattttc attatggatt acaatactgg
    33721 gaaagaatta gctagagtaa aagctgatgg aatttataga ccggatgtaa atcaagcgta
    33781 tgggacatct ggaaatgttg gctatcatgt atcttttaac atgcgtaact tccctaataa
    33841 gaaagtctat gtcatgatgc gtgcaacgaa tgatccagaa ggaaacacta aaggcggtgc
    33901 gcaagatttc catgacaa
//
LOCUS       DAIGQM010000025        33863 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.025, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000025 DAIGQM010000000
VERSION     DAIGQM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.025"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            156..2054
                     /locus_tag="NOA48_001220"
     CDS             156..2054
                     /locus_tag="NOA48_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCI0789493.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(2353..3072)
                     /locus_tag="NOA48_001221"
     CDS             complement(2353..3072)
                     /locus_tag="NOA48_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCI0789494.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            3409..3741
                     /locus_tag="NOA48_001222"
     CDS             3409..3741
                     /locus_tag="NOA48_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789495.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            3728..5731
                     /locus_tag="NOA48_001223"
     CDS             3728..5731
                     /locus_tag="NOA48_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCI0789496.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            5750..6220
                     /locus_tag="NOA48_001224"
     CDS             5750..6220
                     /locus_tag="NOA48_001224"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCI0789497.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            6241..6825
                     /locus_tag="NOA48_001225"
     CDS             6241..6825
                     /locus_tag="NOA48_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCI0789498.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            6840..7826
                     /locus_tag="NOA48_001226"
     CDS             6840..7826
                     /locus_tag="NOA48_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCI0789499.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            7816..8127
                     /locus_tag="NOA48_001227"
     CDS             7816..8127
                     /locus_tag="NOA48_001227"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCI0789500.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            8149..9930
                     /locus_tag="NOA48_001228"
     CDS             8149..9930
                     /locus_tag="NOA48_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCI0789501.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            9923..11299
                     /locus_tag="NOA48_001229"
     CDS             9923..11299
                     /locus_tag="NOA48_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCI0789502.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            11306..11941
                     /locus_tag="NOA48_001230"
     CDS             11306..11941
                     /locus_tag="NOA48_001230"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCI0789503.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            11971..13326
                     /locus_tag="NOA48_001231"
     CDS             11971..13326
                     /locus_tag="NOA48_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCI0789504.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(13518..14912)
                     /locus_tag="NOA48_001232"
     CDS             complement(13518..14912)
                     /locus_tag="NOA48_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0789505.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            15004..15975
                     /locus_tag="NOA48_001233"
     CDS             15004..15975
                     /locus_tag="NOA48_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI0789506.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            15972..16754
                     /locus_tag="NOA48_001234"
     CDS             15972..16754
                     /locus_tag="NOA48_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCI0789507.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(16923..17294)
                     /locus_tag="NOA48_001235"
     CDS             complement(16923..17294)
                     /locus_tag="NOA48_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0789508.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            17428..17871
                     /locus_tag="NOA48_001236"
     CDS             17428..17871
                     /locus_tag="NOA48_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCI0789509.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOA48_001237"
     CDS             complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOA48_001237"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCI0789510.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(18742..20109)
                     /locus_tag="NOA48_001238"
     CDS             complement(18742..20109)
                     /locus_tag="NOA48_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0789511.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(20093..20923)
                     /locus_tag="NOA48_001239"
     CDS             complement(20093..20923)
                     /locus_tag="NOA48_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCI0789512.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            21086..21523
                     /locus_tag="NOA48_001240"
     CDS             21086..21523
                     /locus_tag="NOA48_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCI0789513.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            21599..22219
                     /locus_tag="NOA48_001241"
     CDS             21599..22219
                     /locus_tag="NOA48_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCI0789514.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            22408..22914
                     /locus_tag="NOA48_001242"
     CDS             22408..22914
                     /locus_tag="NOA48_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCI0789515.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            22931..23830
                     /locus_tag="NOA48_001243"
     CDS             22931..23830
                     /locus_tag="NOA48_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCI0789516.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            23917..24801
                     /locus_tag="NOA48_001244"
     CDS             23917..24801
                     /locus_tag="NOA48_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0789517.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(24993..25064)
                     /locus_tag="NOA48_001245"
     tRNA            complement(24993..25064)
                     /locus_tag="NOA48_001245"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25029..25031),aa:Arg,seq:ccg)
     gene            25124..26458
                     /gene="rpoN"
                     /locus_tag="NOA48_001246"
     CDS             25124..26458
                     /gene="rpoN"
                     /locus_tag="NOA48_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCI0789518.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            26607..27698
                     /locus_tag="NOA48_001247"
     CDS             26607..27698
                     /locus_tag="NOA48_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCI0789519.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            27739..28740
                     /gene="gap"
                     /locus_tag="NOA48_001248"
     CDS             27739..28740
                     /gene="gap"
                     /locus_tag="NOA48_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0789520.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            28850..30040
                     /locus_tag="NOA48_001249"
     CDS             28850..30040
                     /locus_tag="NOA48_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCI0789521.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            30144..30899
                     /locus_tag="NOA48_001250"
     CDS             30144..30899
                     /locus_tag="NOA48_001250"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI0789522.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            31015..32313
                     /gene="eno"
                     /locus_tag="NOA48_001251"
     CDS             31015..32313
                     /gene="eno"
                     /locus_tag="NOA48_001251"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCI0789523.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            32712..33851
                     /locus_tag="NOA48_001252"
     CDS             32712..33851
                     /locus_tag="NOA48_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCI0789524.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        11186 a         5996 c         7209 g         9472 t
ORIGIN      
        1 aaaaatatag aaggaagctg gacatttatt gttcccagct tcttttttgt atagacctat
       61 ttctattttt ttattatatt ggatatatat attcattgaa aatagagcat aacaacttta
      121 taatgttgag tataccaatt tttggaggcg ttttaatgga ccgctattta gatttacttt
      181 cagagaagtt ccctacaacg gaagatgtca tcacggaaat catcaatctc gaagcaattt
      241 tgcagcttcc aaaaggaaca gagttatttt tgagcgatat acatggcgaa tttcctgctt
      301 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gaccttttct
      361 ctgaacaaat gacggaaacg gagatcagcc aattcactat ttttacggct tatccagaat
      421 atgtgttgac gactgattgg tacaaaaaac aagataaatc ccagctgatc catcgtttga
      481 tcgatctttt acggtttacg acagtcaaat acactcgatc aaaagttcga aaaggattgc
      541 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgatcgt atcaacggga
      601 aaaaagacta tgtaaaaaaa atcattgaac aacttgtctt gatgaaggaa gaagaaaaat
      661 ttttaacaaa acttgcgcag acgatccaaa aatctgtcat cgatcatttg catatcgtgg
      721 gtgatatttt tgatcgagga actcaagcag ccaaagtaat ggatcgaatc atggattttt
      781 cctctgtaga tatccagtgg gggaatcatg atattttgtg gattggtgcg tattgcggct
      841 ctgaggcatg tttattgacg cttttacgga ttgccgcacg ctacaactat ttatttgaat
      901 tagagaaaga atatggatta aatttacgtc cattattttc ttttgcccat caaacctatc
      961 agaagaatcc agtatttacc cctaaaaaca ggaaagatct atctgaaaga gagcaagaag
     1021 aattagaaaa gatccatcaa gcactttcta tcctccaatt caaatcagaa catcagttgt
     1081 tgaatcgacg acctgaattt aaaatggacg atcgtaaatt gttggaaaaa atcaactatg
     1141 aggaatcaac gatcgtttta gaaggtcagc tctatgagtt gaaagggact tgttttcaaa
     1201 cgatccagcc agatgatcct aaaaaattct tggaagagga acaaaaagtg atcgatagtt
     1261 tgatgtattc attccagcac tcgttaagaa tgcaaaaaca catgacgttt ttgatcgaaa
     1321 aagggggaat gtatctcacg aacaatcagc atgtactgtt ccatggctgt atacctgtag
     1381 atgaaaaggg gcagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
     1441 tgggattttt tgaaaaacag ataactgaaa gcgcaaaaga tttgactgca aatgaagatt
     1501 tggcgaccga tttgatttgg tatgcgtgga gcgggccatt ttcgccttta ttcggcaaga
     1561 gtaaaatggc aacttttgag cgctattttc tcacagagcc tcatacgcac gtcgaaaaaa
     1621 gcaatcccta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttggcagaat
     1681 tcgatgcaaa agaagaaggt tcagcaatca tcaatggaca cacgccagta aaagtaaaaa
     1741 aaggagagtc accgatcaaa gcaaacggaa aagcatttgt tattgacgga ggtctatcca
     1801 aagcttatca aaaaacaacc gggattgctg gctactcatt actatgcaat tcttacggtt
     1861 tccaaatcgt gacacattat ccgttcttgc ctattgaaca acaatttgca aaaaaatctg
     1921 atcaaacgaa tgtaaaaaaa gtgatcgagc agcagctccc acgcaaactt aatcggaata
     1981 cgacaaaagg aatggaatta cagcaacaga ttactcaact ccaaaggctg ttggattatc
     2041 gaaaggacga ttgagaaaaa tgctagccaa cattgctcaa tagactaaaa agcgactgca
     2101 acaaaaggcg tgtcgcagtc tccttcggaa ttagctcaaa aaacggtaaa atattagaag
     2161 ctatttttct gtttatttct ctaatactca ggtcagggcg ctgatttcac gacctcttcc
     2221 ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatatccaa caaacatgag
     2281 aagctgtttt ttgaaattgc tccttgtgac tcagagttga acggcaggct cacgacctaa
     2341 tcagaaaaac gattaaaatt cattcacaaa gaaatcgaat aaacgctgtt cagatgaatc
     2401 tacacgatga gaaagttccg gatgccattg gacaccaagg attttgtgca tattatcttt
     2461 actttggact gcttcaatga gtccatcgtt ggaaaaggcg atggctttta acaaaggaga
     2521 aagatctttg actgcctgat gatgatagga attcacaaag tatgaatcag ggagaaggtc
     2581 acttaataaa ctgtccgaaa cgattttgac ttcgtgagtt gcaaactgcg gggcagtggg
     2641 ctgttgttcg tgttttacgg accattttgg atataatgaa agatcttgat aaagtgttcc
     2701 ctccaacacg acattcaata gttgaagtcc tcggcagact gcaaaaatcg gttttctttg
     2761 tttcaatgct tccaagatca atgcctgttc gaattggtct cgttgaatat ttgtttccgt
     2821 cagttttgga tgagggtctt ccatgtaaag ttgcggacta acatcctgac cgcctgcaag
     2881 aatgagtttg tcgattttct caattagttg aggcgctgaa tctggagaca tgactggcag
     2941 aataagaggt aatccttgag catctaaaac tgcatccaca aatccctgcg gtgtatagct
     3001 tacttgattt ccttggaaag tatctgtcgc tcgaatcagt tgattcccgg caatgccgat
     3061 gattggtttc atttttattc cccctaaagt agactaattg taacaaggat ttaaaaaaat
     3121 ttaaactatg taagacttgc ccctatactt atctgttctt gctgtgttac tatctgtaaa
     3181 gagaattttc gtgtgaaatt catgacgata gttgaaaata ttgcttaatt tgttataata
     3241 aaaagtaagc agaaataaaa aggttgggcg taagcttcaa ggatctagtt cttcaagggg
     3301 tgagaaggac attttattga aggggcctgc ctatactaag ttatctttag aggtacatac
     3361 tttcaatgaa aaaagaaagc atgtacctct tttttaaatc gaaaggaagt gaagcaagtg
     3421 ttagaagctt tggaacaaat ccgaaaagca gaagaagaaa atgagaagcg tgctcgaacc
     3481 ctacggcagc agttgaagac ctatgcagaa gaaaaagagc aagaattgga gataatccaa
     3541 acgaacagtc ggcaacagct gaaacagttg gtagaagaaa aagaacaatt cgaaaagcaa
     3601 gaattagaaa aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca agcaactttg
     3661 aaagaccaat atcaaaagca tcagagtcaa gcaatcggtg caatcattga aagggtgaaa
     3721 gaaacttatg gccgtcacta agatggaaaa agtgaccctc atttcagata aaagaaatca
     3781 ggagaggatt ttacaagcag tacaaggaat ccaaaatgtt gaaatccggg atctgtatca
     3841 aaatagaaca aacaaccagt gggtagaaaa atattttcca gataccacga ttattgataa
     3901 agaagcaaaa ttaagcgctt taggcaatcg gctgaaagac atccaagaag ctatccaatt
     3961 catacaacac cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc
     4021 cttacaagac ttggaagcaa attattccga agaaaatttc atgaataaat tagaagaagt
     4081 ccttgattta aaagaaaagt gggaacagct aactgaaaaa cgtgatcgtt tagaagaaga
     4141 ggaagaatgg cttcttcatt ggcaacagct ggatattgct ccaagtatgt atgcaagtaa
     4201 gacgaccatt tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga
     4261 actaagtaag cttgatgacg tttatatgga agaaatagat tatacgccaa aacaagttta
     4321 tctttcgtat gttgctttaa aaaaatcagt tgctgctata gaagaaattg ctgggaaata
     4381 cgggttcaat aaagaaacgt atccttatga acaaaatcct aaagaaaaat tgcaagaaac
     4441 caaacagcaa ttatccattg ttcacgagca gcaaaaaaag ataacgacag cgttaggtca
     4501 gtgcagcggc tatatccaag aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga
     4561 acgggaaaaa gtaaaagaac ggtttatcca tgccacttat ctgatcgttt tgcaaggttg
     4621 ggtagatgca gaagaaaaac agaatttgat gcatgtgtta aacgaaactg tatcagaaga
     4681 agatatatac gttagtttcg aaacaccaaa ctcagaagag attcagcagg aagtccctac
     4741 taaattgaaa aaccatccgc ttatcgaacc ttttgaattg ctgactgaaa tgtacagtct
     4801 gccaaaatat gaagaagtag atccaacgcc ttggatgaca ccattttatc ttgtcttctt
     4861 cgggatgatg gtcgcagatg ttggttacgg attgctgatg ctcattggga caatactagc
     4921 tcaaaaacta tttgttttac cccgcgggat gaaacgtttc gtaaaattct ttgagattct
     4981 ctcggtacca tcgatcatct ggggattgat ctacagttca tttttcggac aggcattacc
     5041 aaaagaacta tttggtatcc gcttgccttt cccaatccta tctacgacgg atgacgtcaa
     5101 tacgattttg attttatccg tgattttcgg tctgatacag atcttggttg gattattcgt
     5161 ggcagcaaag gaaaatatca ggaggaaaga ttacttgagt gctgtcagtg atggttttgc
     5221 ctggcaaggg atcctgattg ggatcgttat tgcattgatt ggtgtcatgt tgataaaaaa
     5281 tacagcattt gtttatcttg gcgcggggct atcgatcatt gctgctttat gtatcttaat
     5341 cgtgccgatt atccaatcgc cgtctaaagt caagggtgct gccaaaggag cgtataatct
     5401 ttacggattg actggttata tcggtgattt agtcagttat acacgtttga tggcactagg
     5461 tatttcaggc ggaagtattg gcgcggcatt caatatgcta gttgctttca tgccgccagc
     5521 cgctcgattc agtgtaggga tccttttgat catcgcttta cacgcactga atatgttttt
     5581 gacactgtta agtgcctatg tccatggtgc acgattgcag tatgtcgaat tttttggaaa
     5641 attttataca ggaggcggac gtgcctttga cccgctgaaa acggcggaaa aatacgtcaa
     5701 catcaatcat aagaaaaaaa acaataaata attggaggat ttttatacaa tgatggatta
     5761 cttaattagt caaaatggtg gaatggtatt tgcagtatta gcgatggcaa cagcgacgat
     5821 tttttcaggg attggttcag ctaaaggtgt tggaatgaca ggtgaggcag cagcagcgtt
     5881 aacaacaagt caacccgaaa aattcggaca ggctttgatt ctgcaattgc ttccaggtac
     5941 gcaagggttg tatggattcg ttatcgcctt tttgattttt atcaacttag gaaatgatat
     6001 gtcagttgta caaggattga actttctagg cgcttctctg ccgattgctt ttacaggttt
     6061 gttttcaggt atcgcccaag ggaaagttgc agcagcaggt atccaaattt tagcgaaaaa
     6121 acctgaacat gctacaaaag gaatcatttt tgctgcgatg gttgaaacat atgcgatttt
     6181 aggtttcgtt atttccttcc tattagtatt gaatgcctaa gcataaagga ggaaaagcag
     6241 atgaacgcca ttgaaaaaat catctctcag atgaatgaag cagcagagca agaaagagcg
     6301 gcgttagagc aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa
     6361 atcgaaacag aacatcaaaa acaaaaagaa aaacaaatcg aattacttga aaaaaaatac
     6421 cgtcagctta ggaatcgcca acaagtagaa gtacgacaag aaaatttgaa tgcgaagcag
     6481 gaatttttac gacgattgtt tgcagatgca atagctgaaa tggagaattg ggatgaatct
     6541 gaacaaatcc agtttatcaa aaattcattg tattcattac ctttgacagg caaagtaaca
     6601 ttcattgctg gagaaaaatc agcagcttat ctttctcaga cattgctgga tgaatggaac
     6661 aatgaacttc cctttatgat ggttttaagt gatgaaactg ttgctgatca agcgggtttt
     6721 ctgataaacg atcaaggagt tcagtataat tttcttttca gcagccttgt acaagatatc
     6781 caaggaacga tgagttttga gattgccaat caattattcg aataaggagg gatcagtgta
     6841 tggaatacca cgaactaaat cccttgattc gcggaagaga gcttgaactt ttgtccaatg
     6901 agacatttga acggatgatt caaacaaatt ctgtcgaagc acttggtgaa atattgaaat
     6961 ccacgattta cagtccatat atttatgacg gatatgaata tgacttcgaa cagaatcttt
     7021 taaaggagca gagccgtcta tttcgctggt taaaggaatc agcaccggag cctgaaatcg
     7081 tttggatcta tacgatgcgc tatactttcc ataatctgaa ggttttgaca aaagccgaga
     7141 tgacaaatca aaatctggac catttgtata tcgacgatgg attttattca ttagaaacct
     7201 tgaaggatgc cattcatacg caagtttcaa atgaactccc tgaaagcatt atggacagta
     7261 tacgagaagt acgtgattat tttgaagagt ctaccattct tcagggaatt gacgtgattt
     7321 atgatcgaca gtttttgaca gagcagcgac ggcttgccga taagctagga tatcaagaat
     7381 tgctgacaga agtcattgct tttattgact tgaccaatat cacaacgatg gctcgaggaa
     7441 tattgcagaa aagaacatat gggttcatga cgacggtact ttccagctcg ggaagtatcg
     7501 aaaaagaagt atttttgaac tttgtagata aagatatgga agattacacg aattttctat
     7561 tagagacaga ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat cttgatctcg
     7621 taaagcttga acagttgaaa gatgattatc taagttcatt gtatcaagaa gcacaaaccc
     7681 aggctttcgg accactgcca ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa
     7741 accttcgttt actggttatc ggcaaaagaa gccatttcga accagaaaca atcagaaagc
     7801 gggtgagaca agtctatgac gcataagatc ggtgtagttg gcgacaaaga ttctgttttg
     7861 ccattcaaat tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag
     7921 gcaattgaag aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca
     7981 gcattgagcc cagaaacgat cgaacgttac aaggaacaaa tgatacctgc tatcgtattg
     8041 attcccaatc atcaaggatc attagggata gggctggaag aaattcaaaa aaacgtagaa
     8101 aaagcagtag gtcaaaatat cttatagtat gaaaaggaga tagaaatttt gcaaattgga
     8161 aaaatcataa aagtctccgg acctcttgta atggctgaga acatgtctga tgccagtatc
     8221 caagacatgt gtctagtggg agatctagga gttatcggag aaattatcga gatgcgtggc
     8281 gatgtggcgt ctattcaagt atatgaagag acttctggaa ttggtccagg cgaaccggtt
     8341 cgctctactg gtgaagcttt atctgttgaa ttaggaccag ggatcatttc acaaatgttt
     8401 gacggaatcc aacggccatt agataccttt atggaaatca cacaaagtaa tttcttaggg
     8461 cgcggagttc aattgcccgc attggaccat gagaaaaaat ggtggttcga accaacagta
     8521 gaagccggag aaacggtgag tgctggagat gttatcggga tcgtagaaga aacaaaagtt
     8581 ataaaacata aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa
     8641 ggttcattca ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat
     8701 ttgacgatgc ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga aaaattaaac
     8761 ccggatgcac ccatgatcac tggacagcga gtgattgata cattcttccc agtgacaaaa
     8821 ggaggagcag cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa
     8881 attgcaaaat gggccgatgt ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat
     8941 gagatgacgg atgttttaaa tgaattccct gaattgattg accctaatac aggagaatcg
     9001 ttgatggaac gtacggtatt gattgctaat acatcaaaca tgccagtagc agctcgagaa
     9061 gcttctatct atacgggaat cacaattgcg gaatatttcc gtgacatggg ttatgacgtt
     9121 gctatcatgg cagactccac ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt
     9181 ttggaagaaa tgcctggtga tgaaggttat ccagcttatc ttggttcacg gcttgcggaa
     9241 tactatgaac gatctggaag agtcattgca ttaggatcag aaggtcgcga aggaagtata
     9301 accgcaatca gtgctgtatc cccgtctgga ggggatattt cggaaccagt cacacaaaat
     9361 acattgcggg tcgtaaaagt attctggggt cttgattcca gtttagccca aaaaagacat
     9421 tttccttcga tcgattggat acaaagctat tctctttatt caacagaagt agggaagtat
     9481 atggatcata tccttcaagc tgactgggca tccatggtca ccgagggcat gcgtattttg
     9541 caggaagaac agcagctgaa tgaaatcgtg cgtttggtag ggattgattc cctttcagat
     9601 aatgaccgtc tgacattaga agtggcaaaa tccattcgtg aagattattt gcagcaaaat
     9661 gcttttgatg atgtcgatac attcacttca agagagaaac aattcaaaat gttgaagatg
     9721 atcttgacct ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta tttaagtgag
     9781 atcatggacg gtaccgtatc gattcgtgaa aggatcggac gaagcaaata tatcccggaa
     9841 acagaattag aaaaactaga tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc
     9901 gtttcagaag gaggcatgag caatgattaa agaatatcgt acgatcggtg aagtcgtcgg
     9961 tccattgatg gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg
    10021 tatgcaaaat ggcgagattc gtcgtggaca agtattggaa gtccaagaag ataaagcaat
    10081 ggtccaaata ttcgaaggaa caagtggtat caatttacgt gactcttctg tacgattttt
    10141 aggccatcct ttagaactag gtgtatcgga agacatgatc ggtcgagtat tcgatggttt
    10201 gggacgaccg aaagataacg gaccagagat cctgcctgaa aagcatttgg atattaacgg
    10261 agaagtaatc aatccagtag ctcgggatta tccagatgag tttatccaaa caggtatctc
    10321 tgcaatcgat catttgaata cattagttcg tgggcaaaaa ttaccagtat tttctggctc
    10381 tggtcttcct cataaagaat tagctgctca gatcgcgcga caagcaacgg tactcgattc
    10441 atcagatgat ttcgccgtag tctttgctgc tattggaatc acttttgaag aagctgaatt
    10501 tttcatggaa gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt
    10561 agcaaacgac cctgcaatcg aacgtatcgc tactcctcgt atggctttga ctgctgcaga
    10621 atatcttgct tatgaaaagg gaatgcatgt tttggttatc atgacagaca tgaccaacta
    10681 tgcagaggca ttgcgagaga tttctgcagc acggcgagaa gttccaggaa gaagaggata
    10741 tcctgggtat ctttacacga acttagctac tttattcgaa cgagcaggaa gaatccgcgg
    10801 actaaaagga tcggttactc aaattccgat tctaacaatg ccagaagacg ataaaactca
    10861 tccaatccct gacttgactg gttatattac agaaggacag atcatcttga ctagagagct
    10921 ttacaagagt gggattcagc caccaattga tgtactcccg tctctttcgc ggttaaaaga
    10981 taagggaact ggacccggaa agacaagaga agaccatgca gctacgatga atcagctttt
    11041 tgcagcctat gcacaaggaa aacaggcaaa agaattagcc gtagttttag gtgaatctgc
    11101 tttatctgat gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt
    11161 caatcaagga ttctacacga accgttcgat tactgaaaca cttgatctag ggtgggaact
    11221 gctatcgatg ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc tggacaaata
    11281 tctgccagaa gggaagtgag ttctgatggc acgattgaat gtgaatccga cccgcatgga
    11341 attgactcga ttgaaaaaac agttgacaac tgccacaaga gggcataaat tattaaaaga
    11401 taagcaagat gaactgatgc gtcaattcat cctgttgatt cgaaagaaca accagctgcg
    11461 tcaagaaatg gaagagtcta tgacagaagc aatgtctgat tttgtattgg caaatgcttc
    11521 gatcacggaa cctttcatcg aagaattatt tgttttgccg gcggaaaacg ttgatttgtc
    11581 tatcgtagac aaaaatatca tgagtgtaaa agtacctgtg atgaattttg aatatgatga
    11641 acagctgaca gacacacctt tggaatacgg gtatttgaat tccagtgccg aactggatcg
    11701 gtcaatcgat cggtttacta ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa
    11761 aacttgtcaa ctgatggcga gtgaaatcga aaagacacgt cggcgagtca atgcattaga
    11821 atatatgacg atccctcaat tagaagaaac gatctattat attcgtatga agctggaaga
    11881 aaacgagcgc gcagaagtaa caaggttgat caaagtaaaa aatatgggta ccactgacta
    11941 agtggtatct ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca aataaagaaa
    12001 cgtttgccgg ctgttcagct tctcgcatta ggattttttc tcctgatttt agttggcggc
    12061 ggcctactta ccctaccatt ttttagtaat agtgggcatg ggacaaattt tatcgatgcg
    12121 cttttcactg caacttctgc tgtctgtgta acgggattga caacattgaa tacagcagag
    12181 cattggaaca gtgctggtca atttttgatc atgcttttga ttgagatcgg cggtcttggt
    12241 tttatgatgg ttccgattct atgctttgca ttgataaaga agaaagtcag tctcagcaca
    12301 cgtattatat taaaagaagc gctgaatcta gaagaagtat caggtgtgat gaagctcatg
    12361 ctttacatcc taaaattggc ctttgttatc caattgattg gtacggttgc tttatctttt
    12421 gtatttgtgc ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc
    12481 tctagttttt gtaatgcagg gtttgatttg ttaggagaca gtttagccaa tcaccagcaa
    12541 aatgtttatt tgatcatggt ggtatctgct ttgatcattt ctggtgggtt aggcttcatc
    12601 gtatggcgtg atttactgga atatcatcag aaaaagaaga tgacgattca ttcaaaaatc
    12661 gcattaaccg ttacaggtac ccttttatta ggcggattcg ttgtgttctt tttcacagag
    12721 cgcaatgggg caacgctagt ggaagggaat atgtttcaac gattggcaaa cacctttttt
    12781 atgagtgtga cacctagaac ggctggatat tattcagttg attacctcca tatgagccat
    12841 gcaggtctga ttttaacgat gtttttgatg tacatcggcg gaacatctgg gtcgacggcc
    12901 ggcggattga aaacaactac gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa
    12961 ggacgtacga gagcggaagc atttggccgt accatccgac aaggcgcagt gttgcgggca
    13021 cttactttat tttttgttac gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg
    13081 actgaaacga tacctaaaac ttctggcatc gaatatattg cttttgaggt cttctctgcg
    13141 tttggtacag taggtcttac gatgggattg acgccagact tgactgcaat agggaaattg
    13201 atcattatag cgcttatgta cattggacga gttggtgtat tgactgtggt cttctctctg
    13261 atgacaaaag cacaaagaac acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt
    13321 ggataatttc atcttctgac agaaacctag tgatttagta aaataagaaa ataaaataat
    13381 ttttcttgct tcttggatac tttaagtgca aaatgttcgt ttattttttg aggcactacc
    13441 cgttgttgaa cctcgggtag tgcctctttt ttattgaaag gaatcaataa gatttgattc
    13501 ctttatttat caataggtta taattcatat ttttttattt tttcttttac gatacttagt
    13561 ccagaagcta aaatttcaag gttattagag gatagggaaa ttcgaacgaa tgcatctggt
    13621 tgcgcacgtg tagtaaagcg tctggaatga taaagtcgga taccgttagc aagaaagtca
    13681 ttctcaatta tcttagggtc aatctcagga tcaactggaa gaattcgata gtaagggaca
    13741 cgattcgttg gtttttctac tttgaaaaga gaatcaaaaa gctgattggc tctttttgta
    13801 agacttaatt tagtttctaa gatcctattt gcttcatttg aatggaggat ttgagtgatg
    13861 acttccacat ctaatccaga agttttcaca tttatattaa aaattgcttg ttctatcttg
    13921 ctttggacat gtactggaac tacaagataa gcaactcgca atccagaaca aataaatttt
    13981 gtcattccag ctaagtagat tgtttggtta ggtaataaat tttggaaagg aggaatgatc
    14041 gtatgttgat agtaagttgt taaaaatgaa tggatatcat cttcaataac ccatagacct
    14101 tctttttcaa tcacttcggc taattgctct cgtcttttgt gagagatttg aaaccctata
    14161 ggattattac aagaaggcat aagaaagaca ccatgaatct tcttttttct acattcctga
    14221 atcaatatat caggtcgcat tccttgctcg tcaaaatcaa ttggaacgat ctctaaatga
    14281 tataactgag ccaattcaat gaaattagcg tatgtatatc ggtctgttgc tattctatca
    14341 cctggagaga aaagtgcaga aagtgtgata gccaatccat tttgaacacc ggaaacaata
    14401 gatagagatt ctaaggacgg aatgactcct tgagttttta accaatttgc tgcagtagtc
    14461 aattgaaaat ttgtgccttt gggatcttgg taattaagca aaccaacaag atttgggtta
    14521 ttactagttg attgaataaa cgggacaacg aatttattac attcttcaaa agaactaacc
    14581 agaccaaaat caatgatatg ttcggttact tcattggtag agatggtgat ggactcaaag
    14641 acattgggag aaataaatgt gccacttcca atattcgtat acagcaaacc tttctcaatt
    14701 ccatatttat aagccttgcc aacggtagta aaatttaaat ctaaataatc agctagctct
    14761 ctttgggagg gtaactgagt gtttttctgt aatttattct ttaaaatatc ttgttctaat
    14821 tgttgaatca acgatcgata ataaggacgc ttcaattttt gtttgtctgg tcgccaagtt
    14881 aacgggtaat tgtcataaga attaataggc attttctcca ctccttaaaa ttgtatacca
    14941 tacaatttta ccattgattg tattgatttt agaagttaat cttttgtgag gagggaattg
    15001 tctatgaaaa ttattaattt tgaggaagta gtagcttctt ttagttttga agaagcgatt
    15061 caagtaatga aaaaatgttt ttttgattat gaaagtggta aaatcagcca aaatcctcga
    15121 ttggtggaaa ttttacctga cggaaaaggc aaaaatatgt ttgcgatgat gcctgcttat
    15181 ttgggggaga acagatattt tggcacaaaa gtcattaccg cttttccgga taatcatcag
    15241 tatcatttac cttctcattt aggagagatt ttcttgtttg atgctcaaaa cggactaccc
    15301 aaagcattga taaacgcaaa tgcagtcacc tggattcgaa cagctgctgt atctgcgctg
    15361 gcaacagatt acttagcaaa tccgcatgca gaaacacttg ctttaattgg agctggtcaa
    15421 caagcattgt cgcatttgac tgcgatttct accattcgtc ccatcactac agtgtttgtt
    15481 tacgatattt tagaagaaag acgaaatact tttatcgcta aagctaaaaa acagtatcct
    15541 aaaataacgt ttataaatgc aatatcagta gaagatgcag tacgtccagc ggaaatcatt
    15601 tgtacgttga cctctagtaa agaggcattt cttcaaaaag agtgggtaag ggaagacgca
    15661 catatcaatg ctgtgggcac atttactcct gatacaagag agataagtac atcgttgatg
    15721 gaaacttctc aaatctatgt agatgattac tcagctgcct taacagaaag cggggacctg
    15781 cttatagcca tggcagaagg agatttagag gaatcttgta ttgttggtac attaggcgaa
    15841 ttagtttctg agaaaaaaac attttataaa ggagaatcga ggccgacgat tttcgacgca
    15901 gttggtctag ctattgaaga tctttgttgt gcagaatata tttataacaa attagagaaa
    15961 ggggctttaa aatgaactta gattattacg tagttgatgc atttgcagat gaggtgttca
    16021 aaggaaatcc agcagcggtt tatgtgctag aagaatggct gccagaaggt acgatgcaaa
    16081 aaattgccat tgaaaacaat ttatctgaaa cagcatttac agtgaagaaa aaccaagaat
    16141 ttgagcttag atggtttacg ccagatcgag aaatcgatct ttgtggtcac gcgacattag
    16201 caacagcatt tgttttattt aactattaca aaatacctga tgaaacgatt aaattttcta
    16261 ctcaaagcgg taatctattt gtgacaagaa ttaaagatta ttattacatg gattttccta
    16321 gtattatgcc gaaaaaagtg ccgatattgt ctgaatatga agaagcgatt ggggctaaga
    16381 ttaaagaagc ctacttagca cgtgatttat ttttcgtatt agaagatgaa aaaacggtgg
    16441 ctaaattgca gccagatttt acagctatca aaaattttga attaggaata ggagtcatcg
    16501 tgacagcaga aagtgtgcaa aaagactttg tttctagaac cttctttcca aaattaacaa
    16561 tcaatgaaga tccagtatgt ggatcagcac attctaatct tattccttat tgggcagaaa
    16621 gaatgaataa aacaaaattg tcagcttatc aaatgtcatc aaggggcggg gatctagaat
    16681 gtgaattaaa agaagatcgt gtgataatag gaggaaaagc agttttgttt tctaaaggta
    16741 cctcgtttat ttgatttctt tcaaatgaat taaaaataaa ttggtggaga gtggcaacct
    16801 tatagctaca atggttgtta aaaaaagacg caaacttttt caatttaatg aaaagtttgc
    16861 gtctcatttt aattattggt gtttgttttt tattcaatca agagtaaaat gccccatact
    16921 aactatcctc ggatgacttc gattttataa ccatcagggt caatgacaaa gtagtaagaa
    16981 ggcgcagtgc caggtaatcc ttttaagtca gtaatctcaa gaccggcagc tttatgttgc
    17041 tcgtgtaatt tttctagatc atcagctgct atagcgatat gaccatagcc gtctcctaga
    17101 tcatacgcac catgatcata gttgtaagtc aactctaatt catagtcatc cccaggaagt
    17161 gtcaaataaa caagtgtaaa tttgttttct ggaaaatcac ggcggcggct ttcttcaaaa
    17221 ccaaatgcct tttgataaaa ttcgattgat gcttcaagat ctttcactcg aacacatgtg
    17281 tgagccattt tcatagattc atctctcctt ttccttttac tcaatcataa caaaaagaag
    17341 taaggaaata gttgatttgt gcttgttcat gagaaatttc tcatgtaaaa tggatagaaa
    17401 ataaaactgt taaggtggaa actattcatg gataaaccaa tttttggtga aaaaaagcaa
    17461 tttgctgatt atcaaacccg ttatgcagca tatattgtca tagaaagaga tcagcagatt
    17521 gcagtaatcg aggctccaaa tggtgctttt tttcttcctg gcggggaaat tgaaggagaa
    17581 gagacgaaag aagaagcgat tgtccgtgag ctgatagaag aaatgggaat tgtggcagaa
    17641 atttcttctt atctgggaga agctgatgag tatttttact cgaattatcg tgcaacttat
    17701 tattataatc caggatattt ctttgttgct gattcttgga agcgtatagg agaaccaact
    17761 gaaaagacca ataaaatttg gtgggtgagc cctcaagaag cgcttgtgaa attgaaacgt
    17821 ggtagccacc gatgggcagt cgagagatgg atcgaaaaaa ataaaaactg aaagaaagcg
    17881 agtagatcag ctttctctca gtttttttat ttattacagt acatattttt tgattgcttc
    17941 agctacaccg tgctcgtcgt ttgatgaagt gatgacattt gctgcttctt tgacaagaga
    18001 aacggcattt cccattgcta ctcctagacc agcatattca atcatggata agtcgttctc
    18061 gttatctccg atagccatga tttcatcttg atcaatacca aggtgctgtg cgagattcgc
    18121 aactgccgca cctttacttg cttctttatt tagtacttcg aagtaatagg gcgcactttt
    18181 gaccgttgtg tatttatcac ggaaagtttg cggtaaacgc gcaattgctg catctaaaat
    18241 ttctggttcg tcgatcatca tcattttgac gatgttcatg tctggtgtca tttcttcagg
    18301 tgttcgatat tttagcggca tcttgactaa acttgcttcg tggatcgtat aagcgctgat
    18361 atctcgatta ggcgtgtaga tcgctttgtc atcgatcgaa tggagatgac tgccgacacg
    18421 gcgtgccatc acttcgatct ctaggaaatc ttcatgtgtc agtccgtgac gggcgatgat
    18481 tttacctgat ttcgtttgtt gtacgagtgc cccgttataa gtaataacgt aatcattatc
    18541 ttgaaaaagg ttcaactcgt ttaactgttc ctggacacct ggtaagggac ggccagtgca
    18601 taaaacgatc gaaacacctt ttgcaacagc agcggcaatc gcttctttta cttcttttgt
    18661 tacttctctt ttctcattta ataaagtacc atcgatgtcg atagcgacta gtttgataga
    18721 cataatttcc tccaatatat tttaatttat ttcaatcaat gcgccattac ggatatggct
    18781 ggcaaattct tgataagttt cgtcaaataa atcataatga tcacgcaagg acggatcaac
    18841 catttctttt ggaaagaaaa atcgctcatc tccttgttct tgtcccgcta atgcagcaac
    18901 aagctgacta acctgtgata attctatcaa agttccgtca tttcgcaaaa tctcgatttg
    18961 tgtgcgatgt ctgccttgtt ctgggcgata aaaatcataa ggtagatcgt agctagaatt
    19021 cacagcagtg taataaacag gattatatcc gaccttttct actaacaaag tgagttcttg
    19081 gactaatttt gaatcccggt tgccagaaaa agtagcagat ttcagtggtt tacgattcaa
    19141 aaaacgttta gctaaatcat ttaaaatagg atcagcagat tcagaccatt gagtaaagta
    19201 agtgcccaag accccatcat caagtttgag gtattcttct aaagtaaagc ttccgtcaag
    19261 aaatggcaga agtaattgag aatggagttc aaaactgctg gcatcttctt gatacaactc
    19321 gtgtgcgcga tgaagcagat gctccaaaat tacttccata ccacgggaaa caggatggaa
    19381 gtacacttgc acatacattt gatatcggct aacgatataa tcttccactg catgcatgcc
    19441 actcatggaa aaagcgatcc cgccttcata aggacgaatc acacgtaata ttcgggtaag
    19501 atcaaatgtt ccatattctg ttccagtgaa ataagcatcc cgaagcaaat agtccattcg
    19561 atctgcatcg atctgactag aaatcatttg gacaacttgt gggttggggt aagttttttg
    19621 gatcacacta gctacctttt caggaaaacc ttcttctact cggttaagaa tctgatacac
    19681 ttctgtttct ggagaagtga tgatctctac agtgatggct tcatgattcg tatggaagat
    19741 atgttcaaat gtatgagagt aaggaccatg accgacatca tgcaacagtg ccgcacataa
    19801 agtcaccagc cgttcctgat catcccagcc tccgttgcct attttttctt ttgaaaaatt
    19861 tcgagaaaag atatcgcaga ttcgtcttga aatctcataa acgcctaatg aatgagtaaa
    19921 acggctatgt tctgctccgt gaaaagtgaa agaagaagtg cctaattgtt taatgcgtcg
    19981 tagacgttgg acttctttcg aattgatcaa atctaagatt acttgatgct ggacatggat
    20041 atagttatgg actggatcac gaaaaacttt ttccataggc agcatttgat atttataagg
    20101 ggttgtcata atgtagctcc tttatgttat tacgttgttc cattctctgg atttggttgt
    20161 tccattgctc cagctggatt tcttttttta gccagtcggt agaatcctgt aaatcacttg
    20221 cagaatacag cttttcaaaa gcttttgcaa atgcttcttt gacttctttt acaaaaaggg
    20281 gttggtcaag cagttcttca agtgttgcca ttgtagcagg atccactgca ggatagccat
    20341 ttgtaccaaa gtcttctttt aaagcagatt gataaaatcg cttcatgact tgcccgcgtt
    20401 tttcctgatt accgttgaca cttaagtaca tcataacaga aatcccattt ttgatccgac
    20461 gctgagcgat accggcaaat tttttgccat ggatgcttaa atcataagtt ccaggacaat
    20521 aagaatgggt gatttcgaat gcttgtatcg gtgcctttgg aaaagcgtat ttagtcaata
    20581 ggagcatttg ctcgtaagcg tcatctatgg ttattttttt tgtgtcactt tgggggaaaa
    20641 tcaaagaaat attcaaaatt ccttcatctg atacgatccc taatccacct gaatttctga
    20701 tcactggagc gtaacctgca tctttcagtg tttggatccc gtcacttaga aaaggagttc
    20761 gaacatcctt catacctaag atgactgtgc agtcatattg ccagaaatgt aaaaagattt
    20821 gctggtgttc tttagaatat tccgttaata tatctgttaa tgcaaaaggg gaaaagtcgt
    20881 ttttttgata aatgtgctga tctagtcgaa tcgcagggtt cattcaaccg gctcctttgt
    20941 ataaattcat attttctaca atattatact ctaaaatcaa agagttgttt tggaaaaaag
    21001 gttttctgta aaaatggaca agttggttga caaaacaaaa gaaactagga acaatgtagc
    21061 tatgagaagt aaaggagaat gaataatgga attatcacaa ggaacaccga tttcaatcaa
    21121 attgcgtaca aaagtaaaac agcaagggga agtgcaagat ttttattttg atttgaaagg
    21181 gcaaatggtg acaattggcg atacgctgta catacgttat aaagagattc aggaggagac
    21241 gggcgatgag attcctgtaa cgatcaaatt agttccagat ggtcatgtac agctgatccg
    21301 tgcaggagaa atgcggatgc gtttgaaatt tggctataaa gaacggttag aaacatccta
    21361 tcgaacacca tacggtatga tccagattgc tacttttacg aaagaactgc atgttagttt
    21421 gaaagaccgt cccacaggag ggaaggttcg aatcgattat gatctgttca tgggaccgga
    21481 aaaaatcggc gaatattatt tgaccttgga ttttacagcg taaatataaa agaaaagttt
    21541 gattttttgt gtctgatttt gtatgataag gagtagactg tgaaaggacg tgtcctgatt
    21601 ggaaattagt gtatttgaag gtgcaaacaa aagcgaatta tcaatgatcg aagtagcaca
    21661 cgcgatctta gaacaacgtg gcgatgtcat ggatttttct gatttagcta accagatcca
    21721 aaactatctt gggaaatcag acagtgaaat tcgtgattca ctcgcacaat tttatactga
    21781 cttgaatatt gacggcagct ttatctcatt aggggataat cgttggggct tgcgttcatg
    21841 gtatgctatc gattcgatcg atgaagaagt aaaccatgga atggacgaag aggatgaaga
    21901 tactccacgt cgccgtaaac gcaagaaagt caacgccttt atcaatgatg atgaagacgc
    21961 gatcgattac aatgacgatg acccagaaga tacagatctg acagaagaag atgacgatga
    22021 tctgtttgat gacgatgatg atgaagatga agaaatcgct gcttataatt ctgacttgca
    22081 agaaatcgga gcagatgacc cgacagatga tgaagaagac ttgccaggaa atatcgaaga
    22141 agatttaagt atcatagacg aagacgatga tgatgaagat tatgaagagg aagaattttc
    22201 tgactctgaa aaagaataaa cattattttc ttacgagagg ttgtgacaga gacgatcagc
    22261 ctatcagaat aaggaggtgt gacacgattt ttgtcacacc ttcttttttg tatataaaaa
    22321 tcccaagtaa atacataaaa aataaaaaaa ttgaaacttt tagcgcacct tgtacgtcat
    22381 attaagtgag gcagaaagga gtggagaatg atttttactg gatataagaa aaaacggcag
    22441 atcgaaaaat accgtcacct gctgaatgga ctcatcgaaa ctgattatca aaaaatgttc
    22501 cgtatcacga tgaattacgt acatgataaa gaagaggcct tagatgtgat gcaagatagt
    22561 tttcataaag ccctgaacta ttttgaaaaa gaaaaagaga tcgagcattt tagtgcatgg
    22621 ttttatcgga tattgatccg cacggcatta gatagttggc gcagacaaaa aaggacgcct
    22681 gtggacttat ttgaaattca agatatcccc caacagttac ctttagaaac ttccgttgca
    22741 gagctccata tgattttaga taaaatagac agtccggaaa aagagattct gatcctctac
    22801 ttttttgaag gatttcgttt gaaagaaatt gcgactatct tggatatgaa tgaaaacaca
    22861 gttaaaacga aaatgtaccg ctcattgaat gctttacgtc aaatcctaga atgaaggaga
    22921 gaagagtgcc atgtattccc aaaaagaaaa tttaaaaaaa ctaaagaaaa cttataaaga
    22981 acaagcaatt cccaaagggc ttaaagagga gatccgccag cgttttatta tcgaagagca
    23041 atcatttata aaagcaaagc ggagaaagag acgtctccaa gggttcggag tatctttggc
    23101 tatcgtaatg attacaacaa gtagccttct ttttaatagt caagttcgaa gctttgcaga
    23161 agatttaccc atcttaggat cagtcattga attgatctta ggcgaacgct ttactgatcg
    23221 atctgaaaaa atcgatattc aggtaccgaa gatcaataca caaaatgaga aagaaaataa
    23281 aacaattcat ggattaaatc aaaaatactt tcgcgaagga caagcagatt ttgaaaaagc
    23341 tgaaaaagaa tatggaaatt ttgaaacgga tcattaccaa gttttgggag attatcagaa
    23401 aatcgtagac gataaccggt ttctcgtgat tgaaaggcag atcacccaaa cagcagcaga
    23461 tagccatgtt gaaaaaagat acgacacaat cgacaagaaa aacagtgtcc agctctcact
    23521 tccactttta ttcaaagatg acacctatct atctgttttg acaaaagaag tcaaacggca
    23581 gatggccgaa caagtcaagg aagatccatc taagtactat tggactgagc aagatattca
    23641 agaagggacg atagaaaaac caacacttgt tacgcctaca cgaagttttt atttgaacaa
    23701 agagcatcaa ttagttttga ctttttctca atacgaaatt gctcctggtt atatgggtac
    23761 accagaattt gtcattccta agtccgtgac aaaaacgatt ttggcatcgg aagattattt
    23821 ggatcattag acgagaagta gttgcgacta gcagtttcaa ttttcaagta agtacaagta
    23881 aataataaga agagaaaaag agaaagaaga gatatagtga aaagaaatta tttagttatc
    23941 agtattattg ctttatccgt gcttttgttt ttcgaaatta cttcggtggc ctccttgatc
    24001 accgaagtaa aaggacaaac acactcttcg gagcattcgt cacaatcttt caaacaatca
    24061 gaacaatcaa ccattaaaag ccaatcaact gaaacagcta acgtcaaaga agccattcaa
    24121 gaatcagcgg aaaaggtaca aagtcagtca tcacaatcaa cacaagacag tacaaaaacg
    24181 agccgagatc cggctgtcaa aagcgtcgca atcagctttg atgatggacc aggagcgacc
    24241 acaacaccgc agcttctgcg aatcttaaaa gaaaaaaacg tgcatgccac ttttttcgtc
    24301 ttaggagaaa atacggcgca gcatcctgaa atcgtgaagc agacagctga agcagggcac
    24361 gagattggca attacacata cgatcatcag aatctggcca ctctttctgc ccagtcgatg
    24421 acggaggaag tgacgaaagc agacactgag atcaaaaaag tcactggcaa aacccccact
    24481 tttgttcgtc cgccctatgg ttctgtcacg aatgtaggag caacgatcat ccagcgaccg
    24541 atcatcgaat ggtctgttga ttcagaagat tggaagacaa gaaatcctga tttgattttg
    24601 cagaagatcc aagcaacagt atacgatggg gcaattattt tattccatga tatctatcct
    24661 gaaacgattc gtgccgttcc tcaagtgatc gattatctga aagagcaagg gtatcgcatc
    24721 acgacagttg gggatttatt agggcatcca acggctgtcg agaactatta tggcagaaac
    24781 gatcatcggc cagttcagta agtgagacaa gtatctttaa taaataacac attttaataa
    24841 gtagttgaac acataactac cttacttgca aaggcttaac aatatctata caggtacaac
    24901 aaaaaactgt ccaccaattt tctttggcgg acagttttca cttaaaaata aagaagcaac
    24961 tattcgtaaa ttatgctaaa atagcagtag aacgcgtcct gagggaatcg aacccccgtc
    25021 tcaagaaccg gaatcttacg tgatatccac tacactaagg acgcaagcac tgggataatt
    25081 gtaactaaac agataaaaaa ttacaagggg attggacaaa aaaatgaaat ttgagcaaaa
    25141 tttttcacaa aaacagcagc agacacagaa actagccatg acgcaacagt tgcaacagtc
    25201 catccaagtt ttacaatata acagtgagga gctgttggca ttcgttgaga atcaagcaat
    25261 ggaaaatcca ttggtggaag ttgttgagcc ggaatggcag ccagattaca taaaagcttc
    25321 ttcatcttct tatgaaggag aagagacaaa ttacctaaat cagattcctg atacaaaagg
    25381 gtctttattt gattcattga tcgaacaagt ccatttgaat taccgagata cttttttgag
    25441 gaaaatcgtt ctttatcttg tagaatacat cgatttgaac ggatttttga cgattagttt
    25501 agaagaagcc ggaaaagaga ttggagctac gcctatccaa atgctcgatg cgttgactct
    25561 gattcagcaa ttagaaccag ctggagtagg tgcacgtagt ttgcaagaat gtctcatgct
    25621 tcaaacagaa cgagatgatt atgcgccgga attagcttat atcgtgttgg aagaatgttt
    25681 tgaggaactg gtggagcgaa aatggaaaga aatcgcacaa cgtttttctg ttgatctaca
    25741 tgctgttcag cagatattcg actatttaca aacgttgagt ccaagccctg gccggatttt
    25801 cgaccgtagc agcgaattgt acattattcc tgatgtccgg gtattagtgg acgacgataa
    25861 aaatgtacaa gttatctcaa accgaaaaaa tcagccaaat atacgctttc aagagagtta
    25921 cttcaaacaa atgtcacaac aagcagataa agaaactgaa aattatttaa aagaacggaa
    25981 acaggaattc gaatggttga agaaaacgat cctacaacgt ggggatacaa ttttgcgggt
    26041 tgctcaagtc attgtttccc ggcaaaaagc tttctttatc gacaaggaac gtccaatcaa
    26101 gcctcttacg ttaaaggaag ttgcaactga gatagatgtg catgaatcca cggtcagtcg
    26161 tgcagtcaac gggaaatatt tggaaacaga tttcggtgta tttgaattaa aaaaattttt
    26221 cactacacga attcctacga atagtacaga acagacagaa gacctttcag cagatacagc
    26281 gaagaaaaag ctgcaggaat tagtcgatca agaagacaaa aacaagccgt tgtcggacca
    26341 gaaattggtt gaattgctga aaaaagatga gatagcgatc tcaagacgaa cagtagcaaa
    26401 atatcgtgat ttattaggaa tcccgagttc atcaaaaaga aaacgttatg ataactaatc
    26461 agtcaaaaga ctagaaaaag tatttcactt tttctagtct ttttagttga aaaacgagag
    26521 cgaaactgtt agacttacag tcgtgaggtt gagatttccc tttattgatg tgaaattcga
    26581 atagttaatt tcttttttta tcgtatatgg gtcgttttaa gtctacattg gacgtaaagt
    26641 gtccaactaa ggagatcgct atgctggatg aaataaaaat gattgaatct gttgcaccag
    26701 atattatcga agtgttgcaa gaacgctata aaattttacg aaatatctat tggatgcagc
    26761 cgattgggcg tcgaagttta tcggaaagta tggggatcac agaacgagtc ttacgaacag
    26821 aaacagacct tttgaaaaat ctgaatttga tcgacacctc aaaaagcggt atgacgctga
    26881 caactaaggg cgaagaagtt tatcaaagcc ttgaaaactt catggatcag cttttaggta
    26941 cgcatcaaac cgaacaacag ttggcagaat attttggtaa ccaacgctgt atcgttgttt
    27001 caggaaacag cgaagagcag accaaagtgg ctgatgcatt cggcgaagcg ctgagcgaag
    27061 ccttagaccg actacttcca gaaggcgaga atatcatcgc tgtgatggga ggaactacta
    27121 tggctgtggt agccgaacaa ttgtctaatc tggaaaataa gaaacggcat aacctgtttg
    27181 tccctgcaag aggcgggatt ggtgaagcga taactgtaca ggcaaattct gtcagtgcaa
    27241 gaatggctgc taaagcaaac ggtaaccacc gcgcacttta tgttccggaa caattaagtc
    27301 tggcaactta caattcttta ctcaatgagc catctatcca agaagtctta aacttgatta
    27361 gtgaagcgaa ttgtgttatt catagtattg ggcgtgcatt acacatggca gcacgtcgta
    27421 agatgactga aaaagaatta gtcatgctga aacaagcaaa tgctgttgcg gaatcttttg
    27481 gctacttttt caatgaaaaa ggtgaagtcg tttataaggt ccctagaatc ggcatagaat
    27541 tgcaagattt ggaaaaagtc ccgatcatca tggcaatcgc gggcggaaaa tcaaaagcta
    27601 aagcaattcg agcttatatg aaaaatgcac caaaacaaac gtggctcatc actgatgaag
    27661 ctgctgcaaa tgagatttta aaaggggtaa ccctttaaaa taaatatttt tttgattttc
    27721 ataaggagga aatcttaaat gacagttaaa gtaggtatta atggttttgg acgtattgga
    27781 cgtctagcat tccgtcgtat ccaagatgta gatggaatcg aagtagtagc aatcaacgac
    27841 ttgacagatg ctaaaatgtt ggcacacttg ttaaaatacg acacaactca aggacgtttc
    27901 aacggaacag ttgaagttca tgaaggttca ttcaacgtaa acggaaaaga agttaaagta
    27961 ttagctaacc gcaacccaga agaattacca tggggcgaac taggcgtaga tatcgttcta
    28021 gaatgtactg gtttcttcac ttctaaatca gcagctgaaa aacatttaac agctggtgct
    28081 aaacgcgttg ttatctctgc tcctggcgga aacgatgttc caacaatcgt ttataacaca
    28141 aaccacgaaa cattaactgg taaagaaaca gttatctcag gtgcttcatg tactactaac
    28201 tgtttagctc ctatggctaa aacattgaac gacaaatttg gtgttgttga aggattaatg
    28261 acaactatcc acgcttacac aggtgaccaa atgactctag acggacctca tcctaaaggt
    28321 gacttccgcc gtgcacgcgc tgctgctgca aacatcgttc ctaactcaac aggtgctgct
    28381 aaagctatcg gtttagtaat tcccgaattg aacggtaaat tagacggagc tgctcaacgt
    28441 gttcctgtac caacaggttc attaacagaa ttagtaacag ttcttgaaaa agaagtaact
    28501 gttgacgaaa tcaatgcagc aatgaaagaa gcttcaaacg aatcttacgg atacaacaca
    28561 gacgaaatcg tttcttcaga tatcgttggt atgacttacg gttcattatt tgatgctaca
    28621 caaactaaag taatgacagt tggcgacaaa caattagtta aaactgttgc ttggtacgac
    28681 aacgaaatgt catacactgc acaattagta cgtactttag aatacttcgc taacttataa
    28741 gatagacaaa cgtacaagtg taaattatag acatgtacat ttaaaagcgg ggaagcaatc
    28801 gcgcttcttc cgcttttttt gataataagt ttattcagga ggaaataaaa tggctaagaa
    28861 aacagtgaaa gatatcgatt taaaagacaa aaaagttctt gtccgtgttg acttcaacgt
    28921 tcctttgaaa gacggcgtga tcactgacga cactcgtatc aaagcagcat tgccaacaat
    28981 caactacgtt ctagaacaag gcggaaaagc aatccttttc tctcaccttg gacgtgtaaa
    29041 aacagaagaa gataaagaag gaaaatcttt agctccagtt gcaaaacgtc taggcgaatt
    29101 attaggtaaa gaagtaacat tcgtacctga aactcgcgga gaacaattag aagaagcaat
    29161 ccgcaacatg aatgacggcg acgttgtcgt attcgaaaat acacgatttg aagatattga
    29221 cggtaaaaaa gaaagcaaaa atgatacaga actaggtaaa tactgggctt cattaggcga
    29281 tgtatttgtt aacgatgctt tcggtacagc tcaccgtgca catgcttcta acgtaggtat
    29341 cgcttcaact ggtatcccaa cagttgctgg attcttgatg gaaaaagaaa tcaagttcat
    29401 cggtgaagca gtagaagaac caaaacgacc aatgattgca atccttggtg gcgcaaaagt
    29461 ttctgataaa atcggcgtaa tcgaaaactt gattcctaaa gcagataaaa tcttgatcgg
    29521 tggcggaatg acttacacat tctacgaagc aaaaggaatc aagatcggta actctctagt
    29581 agaagctgat aaagtggaac tagcaaaaga attaatcgaa aaagcaggcg acaaacttgt
    29641 cttgccaatc gacaatgtct gtgcaccaga attttcaaat gatgttgaaa cacaagtaat
    29701 cgaaggagac attcctgatg gtttgatggc tttagacatc ggcccagcat cagtaaaatt
    29761 atttgctgat acattacaag gtgcaaaaac agttgtttgg aacggaccta tgggtgtatt
    29821 tgaaatgagt aactttgcta aaggtacaat cggtgtttgt gaagcaatcg ctaacttaga
    29881 aggcgcaaca acaatcatcg gtggcggaga ctcagccgca gcagcagaac aattaggatt
    29941 tgctgacaaa ttcacacaca tctcaacagg tggcggcgca agcttggaat tgcttgaagg
    30001 taaagaatta ccaggactag cagcaatcaa cgataaataa acgaccaagt ttgctcaatt
    30061 ctgacgagta atcgaacaaa aggtgaaggg agttttcatg actccctagc catttttcaa
    30121 taaattaagg agtgtgttcc tcaatgcgta aacctattat cgcaggtaac tggaaaatga
    30181 acaaaactgc atcagaagca aaagaatttg ctgaagcagt aaaaaacaaa atcccttcaa
    30241 atgacaaagt tgattcagtc atcggatctc ctgcattatt cttacaagaa ttaatgacat
    30301 cagctgaagg tacagaacta aaaatctcag cacaaaactg ctactgggaa aactcaggtg
    30361 cgttcactgg tgaaacttca ccagcagctc ttgctgatct aggtgttcat tatgtgatca
    30421 tcggacattc agaacgtcgt gaatatttcc atgaaacaga cgaagacatc aataaaaaag
    30481 cgaaagctat ctttgcaaat ggtatgacac caatcctatg ctgcggcgaa tctttagaaa
    30541 cctatgaagc aggcaaaact gctgaatgga tcgaaggaca aattacagct ggtttagctg
    30601 atctttcagc tgaacaggtg tcaaacatgg ttattgctta tgaaccaatc tgggcaatcg
    30661 gtactggtaa atcagctgac gcacaaatcg ctgacgaaat ttgtggagtt gtacgtcaaa
    30721 cagttgaaaa actttatgga aaagaagtat cagaagcagt tcgtatccaa tacggcggtt
    30781 ctgtaaaacc agaaaatatt gctgaataca tggcaaaaga aaatgttgac ggtgctttag
    30841 tcggtggcgc aagcttgcaa gcagattcat tcttgtcatt gttagacgct gtaaaataat
    30901 tgttgaaaat ttgcgaaaaa tgcaagaaat gtttgcacta atgagcaaaa ttaactaaaa
    30961 tcgtatatga gggaaatccc ttaggaaaaa acaaactcaa aggagagaca aaacatgtca
    31021 attattactg atgtttacgc tcgcgagatc ttagactcac gtggtaaccc aacaatcgaa
    31081 gtagaagtat acacagaaag cggagctttt ggccgcggaa tggttccttc aggtgcttca
    31141 actggtgaat acgaagcagt tgaattacgt gacggagaca aagctcgtta tggcggtaaa
    31201 ggtgtaacta aagctgtcga caacgtaaac aacatcattg ctgaagcaat cattggctac
    31261 gatgttcgtg accaaatggc tatcgacaaa gctatgatcg ctttagacgg aactcctaac
    31321 aaaggtaaat taggtgcgaa cgctatttta ggtgtttcta tcgctgttgc acgtgcagct
    31381 gctgactacc tagaagtacc tttataccac tacctaggcg gattcaacac aaaagtattg
    31441 ccaacaccaa tgatgaacat catcaacggc ggatcacatg ctgataactc aatcgacttc
    31501 caagaattca tgatcatgcc tgttggcgct ccaacattca aagaagctct acgtatgggt
    31561 gctgaagtat tccacgcatt agcttcaatc ttgaaagctc gcggattagc aacttctgtt
    31621 ggtgacgaag gtggatttgc tccaaacctt ggttcaaacg aagaaggttt tgaagtaatc
    31681 atcgaagcaa tcgaaaaagc tggctatgta cctggtaaag acgttgttct tgctatggat
    31741 gctgcttctt cagaattcta cgacaaagaa aaaggtgttt acgtactagc tgactcaggc
    31801 gaaggcgaaa aaacaactga cgaaatgatc aaattctacg aagaattagt ttctaaatat
    31861 ccaatcatct caatcgaaga tggattagac gaaaacgact gggacggatt caagaaatta
    31921 actgacgtat taggcgacaa agttcaatta gttggtgacg acttgttcgt aacaaacact
    31981 caaaaattat ctgaaggtat cgaaaaagga attgctaact caatccttat caaagtgaac
    32041 caaatcggta cattaacaga aactttcgaa gctatcgaaa tggctaaaga agctggctac
    32101 acagcagttg tatctcaccg ttctggtgaa acagaagatt caacaatctc tgatatcgct
    32161 gttgcaacaa acgctggcca aatcaaaact ggttctctat cacgtactga ccgtattgct
    32221 aaatacaacc aattactacg tatcgaagac caacttggtg aagttgcaga atacaaaggt
    32281 ttgaaatctt tctacaactt aaaaaacaaa taattctttt ctaatgaaga tacatgatcg
    32341 actattgaaa gatagtcgag tatgatcact tagttaagta atcgaactct ctacttgctg
    32401 aaatatcagc aggtagagag tttttttgca actagcttct gtatatgatg tttacaaaga
    32461 atggtacaag aaaagatcat ccttgaaaaa ggaaagctaa caataactag catcatataa
    32521 gagcttttaa ggatagaaca gtagaatagg aatctatggg caagtcctct cgtataaata
    32581 aaataggagg gaagtagcag catatttttc ataaagtggc tctctttctt catttttact
    32641 ttggttgctc ctatttgaaa attcgagcac actcaaatac aataaaaaga aatggcaagg
    32701 gagaggatta gatgaaaaaa gaagaaaaaa tcgcgatttt acaagagatt atccgaatta
    32761 aatcagtgaa tggaaacgaa ggtgaagtag cagcctattt gaataagctt ttggcaaagc
    32821 atgacataac aggagagatt gtttcttaca gagatggtag agataatttg attgctcgtt
    32881 accaaaaggg ccaatcagga aaagtgttag gcctatctgg acatatggat gtcgtggcgg
    32941 ctggtgatga atcgtcttgg acctatgcac cctttgcagc agaaatccat gggaaccgtt
    33001 tgtacggacg tggtgctaca gatatgaaga gtggcttggc agcaatggtg attgccatga
    33061 tcgaactgaa agagtcagga aaaccattta acggaacagt caaattatta gccactgtcg
    33121 gagaagaagt gggtgaacta ggtggggaac agctcacgaa agcaggctat gtagatgact
    33181 tagatgcctt gatcatcgga gagccaacca attacagttt gatgtatacg cacatgggat
    33241 caatcaacta tacagtcacc tcgcacggaa aagaagcgca tagctctatg ccagaccaag
    33301 gttataatgc aatcaatcac ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc
    33361 acctcgctga aacaatcgag aatcctgtcc taggaaaaac aatccataat gttacattga
    33421 tcagtggcgg gaatcaagtc aacagcatcc caagccatgc gcagctccaa gggaacattc
    33481 gatcgattcc agaataccca aatgataaaa tcattgcatt gctgcaatca atcgtcaatg
    33541 aattgaatca agagacagac tatcatttgg aattgatgat cgattacaac aaaatacctg
    33601 tcaaagctga tccagattct cctttgattc attgcattca gcaacaattc agccagccat
    33661 tacctttagt tggagcggca gcaacaacgg atgcagccga atttacgaaa gctaaccatt
    33721 ccttcgactt tgtcgtcttt gggcctggtg tcgttacttt gcctcatcaa gtagatgagt
    33781 atgttgaaat cgataattat ttggatatga tcgaaaaata tcaaggaatt attttatcct
    33841 acttagcgta agattttttt aat
//
LOCUS       DAIGQM010000026        33761 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.026, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000026 DAIGQM010000000
VERSION     DAIGQM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.026"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            195..827
                     /locus_tag="NOA48_001253"
     CDS             195..827
                     /locus_tag="NOA48_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789525.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(961..1086)
                     /locus_tag="NOA48_001254"
     CDS             complement(961..1086)
                     /locus_tag="NOA48_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789526.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1220..2113)
                     /locus_tag="NOA48_001255"
     CDS             complement(1220..2113)
                     /locus_tag="NOA48_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCI0789527.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2295..3221)
                     /locus_tag="NOA48_001256"
     CDS             complement(2295..3221)
                     /locus_tag="NOA48_001256"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCI0789528.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3306..4067)
                     /gene="pflA"
                     /locus_tag="NOA48_001257"
     CDS             complement(3306..4067)
                     /gene="pflA"
                     /locus_tag="NOA48_001257"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCI0789529.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4311..6542)
                     /gene="pflB"
                     /locus_tag="NOA48_001258"
     CDS             complement(4311..6542)
                     /gene="pflB"
                     /locus_tag="NOA48_001258"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCI0789530.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6819..9269)
                     /gene="parC"
                     /locus_tag="NOA48_001259"
     CDS             complement(6819..9269)
                     /gene="parC"
                     /locus_tag="NOA48_001259"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCI0789531.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9281..11326)
                     /gene="parE"
                     /locus_tag="NOA48_001260"
     CDS             complement(9281..11326)
                     /gene="parE"
                     /locus_tag="NOA48_001260"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCI0789532.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11492..11926)
                     /locus_tag="NOA48_001261"
     CDS             complement(11492..11926)
                     /locus_tag="NOA48_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCI0789533.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            12053..12691
                     /gene="plsY"
                     /locus_tag="NOA48_001262"
     CDS             12053..12691
                     /gene="plsY"
                     /locus_tag="NOA48_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCI0789534.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGLNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12823..13698)
                     /locus_tag="NOA48_001263"
     CDS             complement(12823..13698)
                     /locus_tag="NOA48_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI0789535.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13780..14571)
                     /gene="codY"
                     /locus_tag="NOA48_001264"
     CDS             complement(13780..14571)
                     /gene="codY"
                     /locus_tag="NOA48_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCI0789536.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14589..15989)
                     /gene="hslU"
                     /locus_tag="NOA48_001265"
     CDS             complement(14589..15989)
                     /gene="hslU"
                     /locus_tag="NOA48_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCI0789537.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(16003..16551)
                     /gene="hslV"
                     /locus_tag="NOA48_001266"
     CDS             complement(16003..16551)
                     /gene="hslV"
                     /locus_tag="NOA48_001266"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCI0789538.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16588..17493)
                     /gene="xerC"
                     /locus_tag="NOA48_001267"
     CDS             complement(16588..17493)
                     /gene="xerC"
                     /locus_tag="NOA48_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCI0789539.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17691..19067)
                     /gene="trmFO"
                     /locus_tag="NOA48_001268"
     CDS             complement(17691..19067)
                     /gene="trmFO"
                     /locus_tag="NOA48_001268"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCI0789540.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(19036..21114)
                     /gene="topA"
                     /locus_tag="NOA48_001269"
     CDS             complement(19036..21114)
                     /gene="topA"
                     /locus_tag="NOA48_001269"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCI0789541.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21236..22093)
                     /gene="dprA"
                     /locus_tag="NOA48_001270"
     CDS             complement(21236..22093)
                     /gene="dprA"
                     /locus_tag="NOA48_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCI0789542.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(22149..22916)
                     /locus_tag="NOA48_001271"
     CDS             complement(22149..22916)
                     /locus_tag="NOA48_001271"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCI0789543.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22909..23769)
                     /gene="ylqF"
                     /locus_tag="NOA48_001272"
     CDS             complement(22909..23769)
                     /gene="ylqF"
                     /locus_tag="NOA48_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCI0789544.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            24029..24427
                     /locus_tag="NOA48_001273"
     CDS             24029..24427
                     /locus_tag="NOA48_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0789545.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24706..25206
                     /locus_tag="NOA48_001274"
     CDS             24706..25206
                     /locus_tag="NOA48_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0789546.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25289..25840)
                     /gene="lepB"
                     /locus_tag="NOA48_001275"
     CDS             complement(25289..25840)
                     /gene="lepB"
                     /locus_tag="NOA48_001275"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0789547.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25992..26219)
                     /locus_tag="NOA48_001276"
     CDS             complement(25992..26219)
                     /locus_tag="NOA48_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCI0789548.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26216..26734)
                     /gene="msrA"
                     /locus_tag="NOA48_001277"
     CDS             complement(26216..26734)
                     /gene="msrA"
                     /locus_tag="NOA48_001277"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0789549.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26754..27467)
                     /locus_tag="NOA48_001278"
     CDS             complement(26754..27467)
                     /locus_tag="NOA48_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCI0789550.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27470..28366)
                     /locus_tag="NOA48_001279"
     CDS             complement(27470..28366)
                     /locus_tag="NOA48_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0789551.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28524..29366)
                     /locus_tag="NOA48_001280"
     CDS             complement(28524..29366)
                     /locus_tag="NOA48_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0789552.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29498..30151
                     /locus_tag="NOA48_001281"
     CDS             29498..30151
                     /locus_tag="NOA48_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCI0789553.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30214..30741)
                     /locus_tag="NOA48_001282"
     CDS             complement(30214..30741)
                     /locus_tag="NOA48_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0789554.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30761..31708)
                     /locus_tag="NOA48_001283"
     CDS             complement(30761..31708)
                     /locus_tag="NOA48_001283"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCI0789555.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31720..33606)
                     /locus_tag="NOA48_001284"
     CDS             complement(31720..33606)
                     /locus_tag="NOA48_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0789556.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
BASE COUNT         8906 a         7071 c         5815 g        11969 t
ORIGIN      
        1 catgatgaat ggatttattc ttcaagaaaa tacatcaatt ttgataagta gaaattgtaa
       61 aaacattgta tagcatttta cacaggagtc tggacttgac ttttttattt attattttga
      121 ttaaaaaaca tcgacatata ctcatcaatt tgttattata ctttatatac ttatcaattt
      181 aatttggaga tattatggaa attcaacgta gaaccactaa ttttttacat ttaggctctt
      241 tttttgcaac tttgacgatc ttattttttc tatgttattc ataccttaag acctcacatg
      301 cgccttctag tgcattaggc tggttgcttt tggatcattc tgatatcaca gaagccgaag
      361 aaaatccgtt ttttttgatt ttgtcttctc tttgcggctt actgttttct gtttatttcg
      421 gtgcctattt ttttcatcga catcctggta cgttaaacga agcttcaagc gtattgattg
      481 catttaaaac gttttctttt ttagcaattc ttttttattc gtttaatcac aatacgcttt
      541 tcttctttat catgaatggt ttagtcgtga ttttatccat ttttacttat tttatttttt
      601 cactcatttt tagccaattg aaatgtccgc tcttctttcg attagttcct gtcacctgtt
      661 ttatttacag cttgttttcc ttttttgtcc ttgctttaat gccactgacc aacccttcga
      721 cgatccaagt cgcaggaaat ctgttggata tgctcttcat cgtcagtcta ggtgtattta
      781 tgtggcaaag aaaaaacaaa caaaataaaa agcattttga agcctgacta ttacgacttc
      841 ataaatgctt ttttagtttt aaacacttca atctaaaaga ataacccaag attggataaa
      901 ttattaatga ctcgccattc gtttcttagt gattctggat tatcaaatgg acttcctaat
      961 ctaatcagct agttcttccc ataaaatgcc atacttgact gaatcataat attgattatt
     1021 taaaaatcta acttttctta tcactacttc ctttgtcatt ccacatttct caccattttt
     1081 ttgcattcct ttgtttccag accatgtagt gaatctaata ggtggtagat aggcaaaata
     1141 ctcaaataat tcttttaacc ataaaggaag agaaaggctc ctcctgcaag agtcagtata
     1201 atttttgctt actgctctct taggttttac tcactaaaac tgttccatat tctttgatat
     1261 aagaaaatgc atgcggtata aatttcttgc tcagctcaga aaagatttgt cgtttaagaa
     1321 aggccatttc ctccattgtc aatgaaggat ccaatgttgg taattcaatc tcaaaattgt
     1381 ttttttcgac aataggtaat tctaatgtga atgattcttc ttcctttata gtattcgtca
     1441 caagtagaga ctgatggaaa atactaggcc ggcgattttt atatttattc ttacgtatcc
     1501 tgtcaacgat aacttctatt tgatcaaaaa agtacgattc atttacgtct ccaataagtt
     1561 cggctaattc tttgaatgcc ttcgttacag gaagctgatt cttctgtaca aaaaagtaat
     1621 tagccaaagt aagcgggaag tgttctatag aggaaagtgt gataaaacgg tacttctcat
     1681 ttcctgcagt tgtcctcagc aattctgtct ctcggctgtt tcttactcca taaaaatacg
     1741 cttctttccg ttcatcttcg aaacaatacg cccaaataac ttctcccatc gctaattttt
     1801 gttcatcaac agagagtctc ttcaattgtt cagctatggt ttcagcagcc gaagtggctt
     1861 gttgcaagta atctttagga tcaaatattg gaaagttcaa atgatatctt cgttcttccc
     1921 tcttgattaa tcctgcatcg atcaataaat caagaaaatg ggaaaattta ttttgcgaaa
     1981 attctttttt caattctctt agaatcgttt cttgttctcg atgttcatat agataatcgg
     2041 tcaatgaaga aaaaagcgga tcatcggtca gtttttgata aaagttttcc ttattttttg
     2101 aataatagtt catatatgtt ctcttttcta tccgttttat tttacttaaa aggcttttac
     2161 gtaaaaagga ggaagaacaa gagtcataat tgactgttat tctcctccat ttcttcggcc
     2221 tttagtatgt tctatgtttc tttttatatc aatcgcttat ccattcattt tgaatgcttc
     2281 atactaccat ttgattagct aaatacagcc gtcaattgag gtacgacttg ttttttacgt
     2341 gaaacgacac ctttaagcaa agcacggttg ttggtcaaag ttgtttggaa agcttcttct
     2401 actttttctt ttcctttacc agcaacaagt aattctgaat cactgtctaa gatgtttgtg
     2461 acaactaata cgaacagatc gtagccattt gctttcattt catcttccat tgctgcttct
     2521 agctctgctt gtcgatccat cacttcatta aggtccactg tattgacttg agcgatacga
     2581 acgttggaac tgcccattgg gaaacttttt gcatccaaat caagaagaac cgcagctgat
     2641 ttatcactta gatttgttcc tgctttcaac atttcaagtc cataagtgtt tagatcgact
     2701 tcagcgattg ctgcaagttc ttttgcagct gcttcatctt caggcgtaca tgttggtgat
     2761 ttgaacaaca atgtatctga aatgatagct gagagcatga ttcctgcgat ttctttagga
     2821 attgttactt ggttttcttt atatagtttt aaaataatcg tacttgtaca tccaactggt
     2881 tctgcacgat agtacaatgg attagctgtt tcaaagtttg caatacgatg gtggtctact
     2941 acagctaaaa tatttacttc gctgatatct gaaatacttt gttggaattc attatgatcc
     3001 acaagcatga catctgcatt ttctgcttta gctgactcta ctactcgtgg tgcagatagc
     3061 tgaaagtggt ctaatgcgta ttgtgtttct tcattaggtg tacctagagc aactgcttct
     3121 gtttctttac ctaattcatt ttgcaagtgt gaaaacgcaa tggctgcccc gattgcatct
     3181 gtatctggat tttggtgacc aaaaactaaa atttttgaca tgtcattcgc tcctttgtga
     3241 tttctcctat ttaataatag caaaaaaacg gaaagaagca atacttatct tctttccgat
     3301 gcgacctatc gcgttaaata ttttgtatac tcttctgtat gaagcaatcg tttagcattt
     3361 tcgacacgtt cttttgtagg tggttcgatc ccttctaatg gatatttcaa accaagtgtt
     3421 tcccacttgt attttcccat cgtatgataa ggaagaatct ctactctgtc tacatttgac
     3481 aaggtttgaa taaagttgtc tagtcggatc aaatattcat cataatcact tcgctcagga
     3541 actagtacat ggcgaatcca aaccggtttg ttgatttttg acaaatattg agccatttct
     3601 aaaatatttt cattgtccca atgcgttagt tttttatgct cttcattatc gatgtgtttg
     3661 atgtcaaata acagtaaatc tgtatacttc atcaattctt gaaaacgtga aaagaaaggt
     3721 tcttcatacg taaaaggttt tccgcatgta tccaatgtag tatgcatctt ccgctctttt
     3781 gcttttttaa atagttcgat caaaaaatcg atctgcaata gaggttctcc accactaaca
     3841 gtaataccac ctttatctcc ccagtaaggt ctgaagcgtt ctgctttatc taaaagttca
     3901 tctgctgtgt attctttccc tccgccaata ttccaagtat ctggattgtg acaaaattgg
     3961 caacgcatgc ggcatccttg cataaacacg acaaagcgca gtccaggtcc gtctactgaa
     4021 ccgaaagttt cgatagaatg aacatagccg attgtttttt cttccattta agttcacatc
     4081 ttttctttga tttcatttta agtacaagtt agctgtcgaa gcgaagcttt ctgaacaaaa
     4141 tttttcgcaa ttgccgcttc gttatgtgta aaatttacag ggacggaaca tacaagtcct
     4201 gcccctgtaa atcgtttctt tcaaataagc atactgatta ttcgattttg atgcgatggc
     4261 tattcaacgt cctttcgacg ctaagtcgaa aaactttttt cacgaacttt ttacattctg
     4321 tcgtgtgaag ttctcatcaa gacatctaat tgttgttctc ttgtcaagtc acggaattta
     4381 actgcataac cagatacccg gatcgtcaag ttcggatatt tcattggatt ttccattgca
     4441 tcacgcaata aatcattact gaatacattg acattcaaat gataagctcc ttttgagaag
     4501 tatccatcta agacattacg caagttttcg attcttgtat cttgttcttt tccaagacct
     4561 gaaggattga ttgtttgggt atttgaaatt ccatccaatg cacagccgta attcatttta
     4621 gctgttgagt tcaggctagc taataaccca ctttgttccg cattgtaact tggatttgct
     4681 cctggcgcaa gtggttttcc agcttcacgg ccatcaggag tatttcctgt atttttaccg
     4741 taaacaacat ttgaagtaat cgtcaataat gaagttgttg gttttgagtt gcggtaagtt
     4801 ttatgacgtt tgatttgtcc catgaagtat tccaagatcc atgaaactaa ttcatctgca
     4861 cggtcatcat catttccgta tttagggaag tcgccatcca cttcaaaatc aactgctatt
     4921 cctttttcat tacggattgc ttttactttt gcatatttga tcgctgacaa gctgtctgcc
     4981 gcatgagaga tcccagcaat acctgtagca aatgtgcgtt gcaagtcaga atccatcaaa
     5041 gccagctgag ctgcttcata agaatattta tcatgcatat aatgaatgat gttcaacgta
     5101 ttgacatata gttctgctaa ccaatccatc atattcatga agttatgttt cacttcttca
     5161 aagtctagta tttctgatgt gattggacga tattctggtc caacttgggc gccagtcact
     5221 tcatcgactc cgccattgat ggcatataat agtgttttag ccaagttagc acgagcgcca
     5281 aagaattgca tgtcttttcc gacaactgtt cctgatacac agcaagcaat cgcacaatca
     5341 tcagaacccc attgttcacg aagctgatta tcattttcga attgaatcga agaactttcg
     5401 atagcgattc tgctagcata tgttctgaat ccttctggaa ggtgttcaga atacaaaaca
     5461 gtcaagtttg gttctggtga aggtcccata tttgttaatg tatgaagcag acggaaatca
     5521 ttctttgtaa ctaatgaacg accatctaat cccatacctg caatggataa agtagcccag
     5581 atagggaatc ctgagaataa ttggttatat tcaggtgtac gcgcgaattt gaccatacgt
     5641 aatttcatta ctaagtggtc gatcaattct tgtgcttctt tttctgtgat tactccatta
     5701 tccaaatcac gttggatata gatatcaagg aatgctgaga tacgtccgat tgacatcgca
     5761 gcaccatttt gtgatttgat tgctgctaaa tatccgaagt atagccattg gacagcttct
     5821 tttgcatttg cagctggttt agaaatatca tagccatatt tcgcagccat ttctttcatt
     5881 tgcgctaatg cacgatattg ttcagtgatt tcttcacgta aacgaatcac ttcttcactc
     5941 attgtatgat aaccagtcat atcatgatct tttttctttt gttccatcaa atagtcgatt
     6001 ccatacaatg ccacacgacg atagtcaccg atgatacgtc cgcgaccgta agcgtctgga
     6061 agccctgtaa tgattttgtt tttacgagca gcacgcattt cagcagtata agcgtcaaat
     6121 acaccttgat tatgtgtttt gcgccagtca gtgaaaatat gtgtcaattc atcgtttggt
     6181 gtatagccat tgctttttag cgcattgtta gccatattga ttccgccgaa cggcatgaat
     6241 gcttgtttca aaggtttgtc tgtctgtaga ccgacgattt tttccaaatc tttatccaaa
     6301 tagcctgcat cgtgtgaagt aatagttgat acgatttctg tgtccatatc atagacaccg
     6361 ttacgctcga attggatatc atttaacttt tgcaattcat cccataattt ttctgttgct
     6421 tctgttgggc cttccaaaaa gctgtcatca ccgcgatatt cagtgtagtt attttgaata
     6481 aagtctctag tgtctacgcc ttctttccat ttggtacctt taaatccatt ccattgctcc
     6541 attgtatgga cctcctaaat ttctgtttta tgtaacagtt tttacgtgat tagtataaca
     6601 cagcacccta tctttgcaag ggttttcttg ttttttattt aacaattttt atgttttatt
     6661 tacatatatt taaatcaacg ttgacatacc aacatttaag cattgtgaac actttcatct
     6721 ttttttgcaa acgtataagg atttattaaa aatgaatgaa aaagagacgc cacctgtatt
     6781 aatacagatg gcgtctcttc attaaaatac tacaacagtt acgactcgat gaaaatctca
     6841 ggagcatcga taacttcgat gacttctcca ccttttttct catccatcgc aaatgatcca
     6901 ttcgatgttc gatcacctat agggaaatca gttgggtcaa tcgttaactg ctgccctttt
     6961 tgattcatca aggttatttc ttttgatctt ccttccgaca tatagataat acggtgcgga
     7021 ttttttttca gctcacgcat gaccgtcact ccccgcttcg cacgtgaagt ttggctgatt
     7081 tcttgagcaa gcatgcgttt aacagctcct cgctgagtaa cgattacgat cggcgtatca
     7141 ccttctgcta acacaagcag cccgttgata atcctatctc catctttcaa attcatagac
     7201 ttcactccag ctgcctttgc tccaacaacg ggaacatctg ttaaaggata gcgcaaaccc
     7261 attccttgat gcgttactaa gaaaacatct aagcctggct gatcttcttt cagatacaca
     7321 gcaatcagtt catcttcttc cgcctttagc ttcatacagc tgagcggacg gctcttatag
     7381 gtgcgccatg gttcgaactc tgtcattcgt gtttgcttga tcaatccatt cttgctgatg
     7441 aatacaaatg ttttctctgc ttgaattttt tgatatggga aaacagctaa aatcgattcg
     7501 tctacagaca gattggagat tgtttgagaa atgtgctcac cagcatcttt ccatttcaaa
     7561 tcgggtagtt catggacagg gcggtagatc acatttgctt tatttgtgat cagaagaaca
     7621 tggtccaatg tactcaattc acctgagtat agcaagtagt cgccttctcg catcccgatt
     7681 tcttctggtt tggaagcact ataagaacga aggcttgttc gcttcacata gccttctcgc
     7741 gtcacactga caattacgtc ttcttgtgcc actaagactt gcgtatcaat tttgatttct
     7801 tcgatttcgt cttcgattgt cgttagacga gcggaagaat aatttttttt cacttctcgc
     7861 aattcttttt tcataacaga gaaaagctct ttgtcatttg aaaggatttt attcaactct
     7921 gtgatttgcg caatcaagct ttcggattcc ttttgaagct ctgtgatatc cgtgttcgtc
     7981 aaacggtata attgcaatgt gacaattgct tctgcttgtt cttctgtaaa ttgaaagacg
     8041 tcgactaaat tctttttggc gtcttttttg tctttacttt cacgaatcgt tgcgattact
     8101 tcatccagaa tcgataaagc tttcatcaat ccttctacga tatgctgtct tttttgagct
     8161 ttggctaaat cgaattgact acgttttgtt atgacttgct ttcgatgctc gatataactt
     8221 cttaaaatgt ctttcagtcc aacttgatgc ggagtcatat ggtcgatagc gaccatattg
     8281 aaattgtaat tgatctgtag ctcagtgttt ttgaacaaat aattcaaaat tccttgagca
     8341 ttggcgtctt ttttcaattc gacgacaatt tgcagacctg ttctatcact ttcatctcgt
     8401 acttcagcta ttccatcgat tttcttattc aaacggatct catccatttt tttcaccaag
     8461 gtcgctttat ttacttcata tgggatttct gtgatcacga tttgctgttt attacccttc
     8521 attgcctcta tctttgtttt cgaacgaaga ataacttttc ctcgtcctgt ttcataagct
     8581 tttttgattt catcttttcc ttgcaagatc cctcctgttg gaaagtcagg tccaggaata
     8641 tattccatca atttttcaag gctcgcttgt ggatgatcga tcatatagat tgtgccatcg
     8701 atcacttcag ctaagttatg agtcgggatt tctgttgcat atccagcaga tatacctgtc
     8761 gatccattga cgagaaggtt tgggtatcga gctggaagga ctgttggttc tttttctgta
     8821 tcatcaaaat tccacacgag atcgactgtt tctttctcga tatctgctag catctctcca
     8881 cttaacttgg ataatctggc ttcagtataa cgcatcgcag caggtggatc accgtccata
     8941 ctcccgttat tcccgtgcat ttcgatcagt acttcccgca acttccagtc ttggctcatg
     9001 cggaccatcg cttcataaat actgatgtca ccatgaggat gataattccc catgatattt
     9061 ccgacagatt ttgctgattt acggaatcct ttgtcatacg tattgccatc tttgttcatg
     9121 gcaaataata tccggcgttg cactggcttc aatccatcac ggatatcagg cagtgcacgt
     9181 tcttggataa tatatttgga ataacgtccg aagcggtcac ccatcacttc ttctaaagtt
     9241 aattcttgta cttcttgtcg attttccatc aggtgacctc ctattctact tcaaataact
     9301 gattgttttc atttttatct gctcgttctt catctaataa atcattagaa actgaaggag
     9361 agatttcagt atcctctttt ttatctaaga tactgccatc ttcttcgagc gtaaattgca
     9421 cgtgattttc gatccatttt cttcgaggtt ctactttgtc acccatcagt gtggttactc
     9481 gacgttcagc ttgcgcagca tcatcgatac ggacgcggat caacgtacgg gaagtcggat
     9541 ccatcgttgt ttcccacaat tgttccgcat tcatctctcc aagtccttta tatcgctgca
     9601 gcatatatcc tttgccgact tttttaatca ttgctgccaa ttcgtcatct gtccacgcat
     9661 attcaatgac ttgcttcttt ccttgtcctt tggatacttt atataaaggc ggtaacgcga
     9721 tatatacttt cccagcttca atcagcggtt tcatataacg ataaaagaaa gtaagcagta
     9781 atacttgaat atgggcgccg tctgtatccg catcggtcat gatgattact ttgtcgtaat
     9841 tacagtcttc gatagaaaac tcaggaccga ctcctgcacc aatcgtatag atcatcgtat
     9901 tgatttcttc atttttcaag atatcttgca ttttagcttt ttcggtattg atgacttttc
     9961 ctcgtaaagg tagaattgct tggaactttc tgtctcttcc ttgtttagca gatccgccag
    10021 cagaatcccc ttcgactaaa tacaattcat ttttcttagg gtttcgggat tgtgcgggtg
    10081 tcaattttcc tgaaagaaga gattcgcctt ttttacgctt cttcccattt cggctttctt
    10141 ctctggcttt acgtgctgct tctctcgctt ctctggcttt gattgcttta cggaccaaca
    10201 tctggctcat ttcgctattt tcctgcaaat aaaagcccat ttgttcactg atgacgttat
    10261 ctactacggt acgagcaact ggcgtaccaa gtttttcttt tgtttgccct tcaaattgca
    10321 gaagattttc aggtacacgg atagaaagta cagcagctaa cccttctctg aaatcactac
    10381 cttccagatt cttgtcccgt tctttcagca aaccaacttt tctcgcatat tcattataag
    10441 atttcgtcat cgccgctttc ataccagctt catgggttcc cccatctttt gtccgaacgt
    10501 tattgacaaa agataaaaca ttttctgaat aaccgtcatt gtattgataa gcgacctcta
    10561 cttcgatacc ttctttttct cctgaaaaat aaacaactgg tgtcaatgta tctttttctt
    10621 cattcagata atcaacaaat tctttgattc cttcttcgta atgaaaaatt tccttgactg
    10681 gttcttctcc acgaagatca gaaagagaga ttttaacgcc ttttagaaga aaggcagatt
    10741 ctcttaaccg ttcggctaaa atttcatatg aaaatttcgt tgtactgaat attgtatcat
    10801 ctggtaaaaa atggacagtc gtcccgtttg ctttttttgt ttttcctatc tttttcaaag
    10861 taccgtcagg tttaccgccg tttttaaatt tctgctgata ctctacgcca tctctaacga
    10921 tcgttacaat tagccatttc gataaggcat ttaccacact ggctcctaca ccgtgcagtc
    10981 caccagaagt tttgtaccct ccttgaccaa actttccgcc agcatgcagc acagtaaaaa
    11041 tcacttcaac tgttggtatt ccggaagcat gcattcctac aggcatccca cgtccgctat
    11101 ctgcaacagt tatactattg tcttcatgga tggtcacatc aatctcactg ccataacctg
    11161 ataatgcttc gtcaactgca ttatcgacga tttcatagac taaatgatgc aagcctcggc
    11221 tgtcagtgga tccaatgtac atccctggtc tttttctaac tgcctctaat ccttccaata
    11281 cttggatgga cgagtcattg tattcgttgt ttactttttt tgccaaggca aacgctcctt
    11341 caataatact ttgcggcaaa accgcaccac gattatcata ctagaaaagg tcgtgaaaaa
    11401 aaagagggta gacgagaaat caattttaat tatctcctaa ccgctttttc gacattcccc
    11461 tctatcgatc atctcttctt tgtggtcatt tttatttttg gttttctttc aacttaccaa
    11521 gttcaatctt aatacaacga tccattacga tatctgtacg tcctgctttt cttagcatct
    11581 cagctgcttc tttgttttca atccctaatt gtgcccagaa cactttagca tcagttttca
    11641 aaaaatcacc tgctatttca ggtaaaaatt cactccgtct aaatacatct acgatatcga
    11701 ttggatcatc gatttctgtc aaattcgcat agactttctc gcctagaatt tcttcaccag
    11761 ccaataatgg atttactggt atgattttat atccattgtc ttgcaatacc tgtgcaacca
    11821 tgtaacttgt tcgttctggt ttattgctca agcctacgac ggcaatattt tttgcttctt
    11881 ccaaatagtt gaaaatcgtt tcttgtgttg gattttttac agacatttct gccacccctt
    11941 gcttttcttt ttattccatc tattatactt gcatctttca ttttttcaat tgttcctgtt
    12001 acctattcat gctaaaataa aggatagttt tcaacttgaa agagggtaaa aaatgaaatt
    12061 gatcttatta cttattttag catatctttt aggttctatt ccttccggtg tctggattgg
    12121 caaattgttt ttcaaaaaag atatccgaca acacgggagc ggtaatactg gaacgaccaa
    12181 tacatttcgt gtattaggca aaacagccgg gattgttgtc ctgcttatgg atattttaaa
    12241 aggtacattg gctacttgtt tgccgatgat cttccacctt tctgggatta accctctttg
    12301 gtttggggta tgcgccattc ttggccatac atttccgatt tttgctgggt tcaaaggagg
    12361 aaaagctgtt gcgacaagtg caggaatgct tttaggactt aatcctgtat tttttgttta
    12421 ttcttgtatc atctttatcg ttagtttatt ttgtacaagt atggtgagtt tgagcagtat
    12481 gatcagtgca gtattgatca ctttatctac gatcgtcctt ccttatgtag ctcctgtgat
    12541 tttggctaag cccaattggt tactgacgat cattgccttt ttagtttctt cctttatctt
    12601 ttatcggcat aaagacaata tcaagcgtat cagaaaccat actgaaagtc gaatcccgtt
    12661 tggtttgaat agcagcaaga aaaaatcctg atactttttc attccaaaga gataaaacgg
    12721 gagtgtgaca aatcgatgtc acactccctt attacttaca ggatagcttt tttacacacc
    12781 ttggtaaacg gtgttccctg ctaacttctc ggtcacaacc tcttacttca ctgtgatgga
    12841 atattttgtc ttgaagattt catgggcacc tagttgattg atccctactt tttccatcaa
    12901 gtttccacta ctgttcaccg tgtcagcgat tccgcaccac ggttcgatac aaacgaaagg
    12961 cgcttctttt ggataaggag accagatccc tacataaggc atatctttat agcttaaagt
    13021 tacgctatgg gaagattttt cacttcgaat ggcgtacgca tttagacccc ttgtttcaaa
    13081 aaccaaggca tcttgctcaa aaagttcacg attcaaagcc agattcgtat ttgtctgacc
    13141 taacgtcttt tgatccatat cgatgaatgg gcctttcaat ggtaggcgta atcttgattt
    13201 caatggagaa aatgccagat agaaatcttc aaatgacaat ccttcttcaa gaggtacatt
    13261 gaaagcagga tgtccaccga tagaaaagaa catttctttt tcaccggtat ttgccacttg
    13321 ataatgaacc gtgatgccgt ctcctcctaa ttcatagctg atcactaatt caaaatcaaa
    13381 tggatacttt tctaatgtct ccggcgtact ccttaagatg aaactagcca tttcttgtcc
    13441 atgttcaatg acttcaaaat ccatatcccg agcaaatccg tgttgcccca tttgatatgt
    13501 tttcccttga taaacatact gatcatcttt taaacgtcca acaaaaggga ataaaaccgg
    13561 tgcatgtctg ccccaatacg ctggatcacc ttgccagata tactctaaac catgttcttt
    13621 tgatttcaga ctgatcaatt ccgcaccgtg ttcagcgatt tcggcgatca gctggtcatt
    13681 ttgaataata acagtcattg ccattcctcc aacttcgact tactttttaa aatgggaagg
    13741 ctggaacaaa catttctatc tgccccagtc cccttacttc taataactgt gttttgctaa
    13801 ctcgtcttta aaacgggaat tcaatacttt taaataagtt cccttcatgc ctaacgaacg
    13861 agattcaatg attccagctg attccaattt tcgtaaagca ttgacgatca cagaacgagt
    13921 gatgccgata ctatcggcaa tattagaagc agtcagacga ccttcatctc catccaatgc
    13981 ttcaaagata gcttgtacag ccttcaattc gctataagat aatgtgttga ttgccatttg
    14041 gacagccgtt gcactccgta catctgcttc gatgcttcga gacttctgat aaaggatctg
    14101 cataccgaca accgtagctc catattctgc taagactaga tcgtcatctg caaacgattg
    14161 ttccatacga gataagataa tcgtacccaa acgttcgcca gctccaaaga tcggaacgac
    14221 agtcgtcaga ccaaatggat atttctctct tgactctacc ggaaatgcag taatatcact
    14281 agtaattggg atattagctt cagttttcat caactgtgcc actgtatcag tataagattc
    14341 aggaaattgt ttctcaacaa acattgtttt gattcgttca ttgttcacat cgtgacgttc
    14401 attataacct agtaatactc cgtcacttcc tatgatatag gtgttgctgt caagaatacc
    14461 acctagtgtg acagccattt tatcgtaagg caaatctgct tgcatgtcaa aagtattctt
    14521 ttgctgcaaa agtgtgttta tcttgcgggt tttcgttagc aagtctgtca ttgtcgtcct
    14581 ccgatttttt ataaaatata gcgacttaaa tcttcatttg ccgcaattga gccaagtttg
    14641 tcatccacat atgcttctgt gatcgttatt tctcccattt gcatatctgg tgcttcaaat
    14701 aatagatctt ctagtagttt ttccaaaatg gtatgcagtc tgcgtgcgcc gatattatct
    14761 gtgtcacggt tgacatcgaa agcgatttga gcgatccgtt caattgcttc ttttgtaaac
    14821 gtaactgaca cattttctgt accgatcaac gcgacgtatt gttttactaa agcattattt
    14881 ggttcggtca gaatcttcac aaaatcttca gctgtcaaat catctaattc tacccgtatc
    14941 gggaagcgtc cttgaagttc tggaattaga tcacttggtt tagacaaatg gaaagctcct
    15001 gaagcaatga ataggacgtg atctgtttgg atgatcccgt attttgtgtt tacttgtgaa
    15061 ccttcgacaa ttggcaatat gtctctttgg acgccttctc tggatacttc tccagattgc
    15121 tgtgatttag aagtgatctt atcgatttca tcgataaaaa taattccact ttcttccgct
    15181 aatttgattg cctcactatg gatatcagca tccttgacta attttgctga ttcttccttg
    15241 atcaataact ctaaagcttc tttgactgtt accgtccgtt ccactttttt cttcggtgtc
    15301 aaagcaccta gagtttcatt taggtcgatc cccatttgct ccaatccatt gttcatcatt
    15361 ggtgcaggtt tcttttggtc ttcaacttca atggttactt cacgactatc cagtaaaccc
    15421 ttttgtagtt gttccaagac tgtacggcga ttgattcgaa tatcttctgt cacttcttct
    15481 tgcggttcag cggtattttg ctgactagca ttaaaaagat tcatcatttg ttcaaattga
    15541 ttagtggatt gtttctgttc ttttttgata ccaggtacca agatttttac caaacgtttt
    15601 tctgcatttt ttttagcact tgtgtataca cggctgtact gctctttttc tacgatttgg
    15661 atcgcatttt ctactaaatc ccgaaccatt gattctacat ctcttccgac ataaccgact
    15721 tcagtaaatt ttgttgcttc gactttgaca aatggtgcat tgacgatttt tgccaaacgt
    15781 cgtgcgattt ctgttttacc gacccctgta ggtccgatca tcagcatatt ttttggtgta
    15841 atatcttgtt gcattttttc atctaactgc aaacggcgat agcggttacg caaagcaacg
    15901 gcaacagatt tttttgctgc gtgctgtcct acgatatatt catctaattc acttacgatt
    15961 tgtcttggtg tttgttttaa ttcatacata tctactcacc tcttacagtt cttctacgat
    16021 aatattatga ttagtaaaga tacagatatc tgcggcaata tttaacgcat tttctgcaat
    16081 ttctttcgca ctcatgtcgt tttgagcata gtttttcatt gctcgggctg cagccaacgc
    16141 aaaattccct cctgatccga tagctaagat accatcatct ggtgtgataa cttctcctgt
    16201 acctgaaaca agaagcattt ctttatcatt cattacgatc agcatcgctt caagtttttg
    16261 catagattgc tgtgtccgcc attcttgagc taattcgaca gctgcgcgtt gtagattccc
    16321 gttatattcg tttagtttgc cttcaaattt ttcttctaaa gtaaacgcat ctgcaacact
    16381 tccggcgaaa cctacaacaa cttctccatt gtagatacgt cgtactttct ttgcagtgcc
    16441 tttcatgaca acagattcac ccattgttac ttggccatct ccagccatag caaatttccc
    16501 gtctttttcg acggcacaga tagtggttga atgaaatggt gattcgacca tgtttgtttc
    16561 ctcctaaatt tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt
    16621 ttgtaaactt tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc
    16681 tagcaattct tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt
    16741 atggcgcagc atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt
    16801 caagacatat tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat
    16861 atcatgctct tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg
    16921 cagagcatct tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg
    16981 gatcaacatg acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact
    17041 taaacggatg cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg
    17101 actatctcct gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg
    17161 cagtctcaaa tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc
    17221 ttctttgaga agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt
    17281 tctgctatag ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata
    17341 ttccgccttc agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat
    17401 gtcttcttca tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg
    17461 caaaaatttt tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga
    17521 ataatttagc acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc
    17581 taagtttgtt cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa
    17641 cgcaagaaaa agagcgagac tatccgtctc accctcttca tggagtttcc ttactcattt
    17701 gggattgcag ttttttctaa ttctgttttt attgcctcat tagcttttaa agctcgttgt
    17761 gcaattgctt catatcttgc ttttttgtct cgaatgcgct ctggcagttc aggaaacaga
    17821 ccatagttgg cattcatcgg ttggaaatgt tttccttccg catgagtaat gtagtaagcc
    17881 atacttccaa tagctgtttc ttgtggaaac tcgactggtt ccatttcttt tgctaagcgt
    17941 gcggcgttga ttccagcaag tagtccgctc gctgcacttt caacatagcc ttctacacca
    18001 gtcatctgac ctgcaaagaa cagatcttcg cgtttcgttg attggtaagt cggtttcagc
    18061 aattctggcg aattcataaa gctgtttcgg tgcatcacac catagcgaac gaattcagca
    18121 ttttctaacc caggaatcat ccggaaaaca cgtttttgct cgccccattt caagtgagtc
    18181 tgaaagccca cgatgttgta taaagaagct gcagcattgt cttgacgcag ctggataaca
    18241 gcataaggac gtttgccagt tttaggatct tccaatccaa ctggtttcat aggtccgaaa
    18301 agcatcgttt tgaatcctcg ctgtgccatt acttcaattg gcatacatcc ttcaaaatat
    18361 ttttctttct caaaagattt aagttctgcc acttcggcat tgattagtgc ctcatggaaa
    18421 gctttgaatt cctcttctgt catcggacag ttcaagtaag ctgcttctcc tttgtcatag
    18481 cgggacttca aatatacttt atccatatcg atcgtagctt tgtctacgat tggtgcagct
    18541 gcatcataga aataaaaacc atctgaacca ttgaatgctt tgatgctttc tgctaatgga
    18601 tgagaagtca aaggtcctgt tgctactacg gtgattcctt ccggtatttc agtaatttct
    18661 tcgtttatca ctgttactaa tggatgctct ttgacttttc gggtaattgt ttcagaaaaa
    18721 gaatcgcggt caacagctaa ggcaccacca gctggcactg ctgtttcatc tgccgaagtg
    18781 attactaccg aattcaatcg gcgcatttct tctttcaata accctactgc attagccaaa
    18841 ctgtttcctc ttaatgaatt ggaacatact agttcagcaa aattacttgt gtgatgcgcc
    18901 tcagtcgatt tgactggacg catttcatat aaacggacag ggactcctgc ttgtgcgatc
    18961 tgccaagcag cttcacttcc ggcaagccct gctccaacaa catttaccat tttcaatgaa
    19021 agaacctctt ttctattatt tttggatgtc ttcttcgtaa tctccattta cacagactac
    19081 ttgtttaccg cctttgactt tcttctcgac cagatatccg tcacattttg gacaatttct
    19141 gcccactggt ttatcccaag aagtgaattc acattctggg aaacgggaac aaccatagaa
    19201 tagtctgttt ttcttagatt ttcgttcaat gacttgtcct tcatgacata ctgggcaagt
    19261 cacaccgatt tcttttacga ttggtttcgt attccgacaa tcaggaaaat tactgcaagc
    19321 ataaaacttc ccatatttcc ctaattttat caccatcgga tgtccacaga catcacaatc
    19381 gaatcctgct ggttcatctt tgatttgaat tttttcgatt ttttcttccg cattcgtcag
    19441 ttctttttca aacggtttat agaaacgatc aaccactttg acccacgctt ccgtgccttc
    19501 ttcaatttta tccaaatctc cttccatttc tgctgtgaaa tggatatcga cgatttgagg
    19561 gaagaattca cagattaatg aattgacaat ttctcctagt tcagtcggct caaatctttt
    19621 ttgtgtcaat tttacatagt agcgtctttg gatcgtatca agtgttggtg cataagtgga
    19681 aggtcgccct accccgtttt cttctagtgc acgaatcaac gtagcctcac taaaacgtgc
    19741 tggtggttga gtaaaatgtt gttttggttc aatatcaaca gattggacta catcgccttc
    19801 ttcaagttct ggaagaatat tttctttctc ttctttgccg tcatctctac cttccacata
    19861 cacttgcatg aatcctttga atttgatttt tgaaccgttc gcaatgaaga tgacaccatt
    19921 ttgttctaat gtcactttca ttgtatctaa aatagctggt gtcatctgac tagccacaaa
    19981 acgtgaccag atcaatgtat aaagtttcaa ttgatcttta tctaaatatt gtttgagttc
    20041 atctggtgta cgaagcacac tcgttggacg cacagcttca tgggcatctt gtgcgccttg
    20101 agcatttttg atctttcggt gatcatgtct agaaaattct tttccatacg tatcttcaat
    20161 aaatgctgcg gcctctgctt ttgctgtatc ggcaatccgg gtagaatcag tacgcatgta
    20221 tgtaatcaag ccgactgttc cttgtttacc caaagtgatt ccttcatata attgctgtgc
    20281 taccatcatg gtttttcttg ttcgaaagtt taacttacgg gcagcttctt gttgcaggct
    20341 acttgtagtg aaaggattcg cagggtttct tttgcgctct ttcttttcta cttttttaac
    20401 ttcgaagtct gttccatcaa ttctagcagt gacttctttt acactttgtg catctggtaa
    20461 tttctttttc ttaccgtcga ttccccagaa atttgctttg aatttcttgc gagctttttt
    20521 aaaattaccg tcgatgctcc aatattcttc tggaacaaat tctcggatct ctttttcacg
    20581 gtcaataata atttttaaag cgacagattg gacacgtcct gcacttaacc ctttcttgac
    20641 cttacgccag agaataggac tgatcgaata accaacgatt ctgtctaagg tacgacgagc
    20701 ttgctgtgca tctactaaat ctacatcgat cgttcttggt tccttaaaag ctgctttgac
    20761 tgcgtctttt gtgatttcat tgaagaccac ccgatttttt tctttcagat ccaacccaag
    20821 taggtacgct aaatgccaag caatcgcttc tccttctcta tccgggtcac ttgccaagta
    20881 aactttttga gctttttttg ctgcggcttt caggcttttg atgacatcgc cttttccgcg
    20941 tatagaaata taatggggtt cataattgtt ttcaaaatcg atacccattt tacttttcgg
    21001 taaatctctt atatggccaa cactggccat tactttatag tttcgtccaa gatatttctc
    21061 aattgtcttg gcttttgcag gtgattctac aatcactaaa tatttatacg ccattactga
    21121 atggactcct ttccattgtc gtgttcctac tattaaaaga ggattcatac aaatcgtagc
    21181 taatcatatc cattcagaaa acgtttgtca agaaaagcaa atgaaaagta tggtgttatt
    21241 ctttaaattc tgccaagata tcttcacccg aaaccgtgca aactgcaccg tcttggatca
    21301 aatgatgaca tccggtagaa tgttctgtta aaatatttcc tggaacagaa aaaactgttc
    21361 ttccaagatc caatgcttgc tgtgctgtta tcagagagcc gctttttttc ttggcttcaa
    21421 agacacatgt tcctttagac aaagctgcga taatccgatt tctcattgga aaacaatgct
    21481 ttttcgggcc ggattgagga ggatattcac tcaaaagaag atgatcattt gcaatcacct
    21541 cttgcaagtc acgattttca gcaggataga cttgctctat ccctgttcca atgactgcga
    21601 ttgtccgtcc accatgagag attgctgctt ggtgaccgta tgtatctatc cctttcgcgc
    21661 agccactgac gatcacatat ccagcttcta tcactggttt tagtaaataa taaactgttt
    21721 ttttggctaa agcagaagtg tgtcttccac caacaacgct taacatgtta caagaaagta
    21781 aagatagatc accattataa aacagtacaa ttggcggata ggtcaagtga agcagctgag
    21841 ggggatattt gggatcaaag caagtgataa acgactgttt cgattggatt ttgccccagt
    21901 tagcgtgaat ttcctgccaa cttttgcgaa acagctcccg gtgtttggtt attttaccta
    21961 tcttaatgat gtcttcaaat ccgatttctt tataaggata ctgcatcatc cagttagcaa
    22021 gtgcccattt tccttgacta ctgattcctt ttgtataagc aagtttcaat aaattttctt
    22081 ctatttgata catcataaaa ccgcctttcg tctctctttc taataagata cgtaaaagcg
    22141 gctgtttttt attgtaaata tttttttaca ggtgcaaaac ttttacgatg gattggcgta
    22201 attccttgtc gttcaagtcc ttctaagtgt tcctttgttc cataacctgc attatgcgag
    22261 aaaccatatc caggataaag cacgtcatat tctttcatca attggtctcg atatacttta
    22321 gcaatgatac ttgcagcagc aatcgacaca gatcgtgcat cccctttgat tattttttcc
    22381 tgctgaatag gcaaatccaa ggtcatcgca tcgatcaaca aatagcttgg tacaatggac
    22441 aatttttcta ctgcttggat catcgctaat ttacttgctt cataaatatt cacatcatcg
    22501 attgtctgct gatcaacgat cccgatcccg attgccaggg ctttttcttg aacttgttga
    22561 taaagaagtt ctcgcttttt ctctgataat tgtttggagt cattcagccc taatatgatc
    22621 tcatttttcg gcaagataac tgcagctgcc acgacaggtc cagctaatgg tcctcttcct
    22681 acttcatcaa tgccggcaat ccattggtga ccttgtgcgt acccttgctt ttcaaagcaa
    22741 aacatttctt catatttttc cttaattaat gcttcctttt tcaatcgtcg ttcaaaagaa
    22801 gccagtgctt gctgcacgcc tttgcgtgga tcatttctta atgattctag tgtaggatca
    22861 tctattctct gtatgctttt caatcgttct ttgatacttt ggatggattc agtcatcact
    22921 tttttgctcc atttcttcgc aacgatccag tgtgtatcgt ccaagttttc cttgacgaat
    22981 atcatgcacg actaattcgc tgccacgatc atagtcttct ttatacccac gttttgctgt
    23041 aatatccatc agtaattccg gtgccaattt ttcttcttgc tcgattgata aaccataacg
    23101 atcgctgatt cttcctgaat aatatcgggc aaaaaagtct aatccgtaaa tcgctaaatc
    23161 atctaaatgg acaagctggt ctttgatcgc gcctgtcagc gctagttttt tgccgatttc
    23221 ttcatcttca aatttgggcc ataaaatccc tggtgtgtct aacaattcca actcattacc
    23281 taaacgaagc cactgctgac cttttgttac gccaggctta tttcctgtct gtgcaatttt
    23341 cttgcctact agtcgattca tcaacgtaga tttcccaaca tttggaatac ctaagaccat
    23401 tgcccgaata gcgcgaggct tgatcccccg agcagcatct cttgcccgtt tttctttcaa
    23461 tgcttcttta gccgcaggta ctagaccttt aattccttta ctttcttgtg ccgtgatagc
    23521 taatgcaaga tggccttgtt tacgaaaata ttcttgccac agctttgtct gttgtggatc
    23581 tgccagatcc gctttattca ataaaacaag gcgaggtttt tgctgaatga tctgatctag
    23641 cattggatta cgagaagata aaggtaatcg tgcgtctacc aattcaaata cgatgtccac
    23701 atatttcatt ttttcagaaa cttctcgtcg ggcttttgcc atatgtcccg gaaaccattg
    23761 gatggtcatt gttctctcca ttcctttcat accggaatat tccccggctt tacttgtttt
    23821 tttctttttc aatataaatt cactttttta ttataaagaa attccatcta ttagttaagt
    23881 gaaagtgaac cagtcctcat tctatcacat cttcactttt ttgatgatgc aaatttttat
    23941 tttggtttct atatatgaat ctaaattttt gacagcgttt cctaaataag agatgataga
    24001 cgaacaaaac agaaaggaga cgaaacaaat gaatagtatg gtttttgtta attttcctgt
    24061 tgctgatgtc aatcgttccg ttgcttttta tgaaaagctg ggttttaaaa aaaatgaaga
    24121 attttctact gaagaagctg gttcaatggt atgggatgac actttttgga taatgcttct
    24181 ctctcatgat ttttataaaa aatttataaa agataaagaa atagctgata ataaaaaaac
    24241 aagtggtgct ttgatttcgt ttagtgttga aaatgcggat gaagtaaaaa aatttgctca
    24301 aattgcaaaa gaaaatggtg gtactttcca cgaagtagat atgggaatgc ctgaagaaga
    24361 aatgttttca ttagaagtcc aagatctaga cggaaataca ttagaacccg tatggatgaa
    24421 gatgtaagca gataactaat ctgacgtttt ttataacaaa aaaacaaagg cggatgatac
    24481 gataagtatt ctccgcctct atttttttta ttcgtacaat ctctttttta cagtttataa
    24541 aagcagtctt ctcacccttt ttttaattgt tagatgccag tgtatgtaaa tcaccaatgt
    24601 gtcatgacac attggtgatt ttatggtatc cttttattat taactgacaa aggagagaat
    24661 attttgaaca ctttgattgc aaaagacgtt tttagattgc ccgaaatgaa tgcaagattg
    24721 ttgtcgacct ctgctctttt attagccctt gatgtcatct tatacaagat agcgattggt
    24781 cctgcttatt ttcaaatcac attcggattt ttaagtatgg cgcttatggg ttatctatat
    24841 ggaccgatct gggctggttt gcttgaaatg ttgtcgaaca ctttaaattt cacgatattt
    24901 ggttcaggaa cgtttcaagc tgcttttctt atcacggctt tccttggtgg atttattaat
    24961 ggcttatttt tatatcataa aaagataaac ctgccttccg tcatcgctgc ccaattattg
    25021 attatgatcc cagtcagcct ttttatcaat tcttggctga tgtctgtttt gtttggtgca
    25081 gatttcaaag taatttttct aggtagattc atcaggaata tgatccaaat ccctattcaa
    25141 ataatggttg tttattcatt tatcaaaact ttagaggcta gaaaagtgtt taaacgagct
    25201 gtttgatttt acgtactaag gtagtaaact gattttggat taaacaataa agcgtgcagt
    25261 ctcaacagac tgcacgcttt attgtttctc actggatcca ttttatttca tcaagtggat
    25321 aatagacaaa tcttgcttta cctagaatat cagttttatt gatcgtgcca aacgaacgac
    25381 tatcttttga aactcttcga ttatctccaa gtacaaaata attatcttcc ggaagcttgg
    25441 attgtcccgt tagctcttgt agtgtaaagt ccgtcgtata ggatgcattt gcatgatctg
    25501 atttcaggtt tttagttaga taaggttcct taactacttt cccattgatc ttcaattgat
    25561 cattttggta gctgacattt tctcctggaa gaccgattac tcgtttgata taaatcgtgc
    25621 catctgctaa ttgaaaaaca acaatatcaa atcgtctgat ctccgaaaat ttttccatca
    25681 caaccatatc accttgcttc aacacgtttt ccattgaatt gccttccact ggtaccggga
    25741 tgaataaaaa tccccgcaac atgaacgcaa ggaatacaga aacaagtaag tatttgaata
    25801 caagccagaa gcgattaata tagcgttgtt tttttgtcaa tctctatcaa tccatccctc
    25861 tttttttcat tctttcttta ttataagaaa aatatcaaaa aaatgcgact agatagctga
    25921 aataaaaata attctttcaa ttaggctatt ggacaaaaaa cttttttgat cataaagtac
    25981 aaaactatct cttatatgtc atgattattt tctaaatatt tttcccatgc ttcgtcaaag
    26041 atatccatgg acggcaaata gtcgacattc agttccagat aattagaaat ttcttcgtag
    26101 ctagagctgt gcttaggaaa ttggatgtct ttaccggctt ctgtagcgaa aacagataaa
    26161 gcatcatgtg tgccaccgcc tcgcagtgtc attaaataat gaaaaaagct tcgattcacc
    26221 cttcgttcct ccaattttct tcgataaagg cagcccggcg tgcatggttt cttttaaaat
    26281 tttcaggatg ctttttataa tactcttgat ggtcttcttc tgctagataa aatggttggg
    26341 ctggttcgat ttttgtaacg attggctgtt cgaaacgtcc actttcagct aactgtttct
    26401 tacttttttc agcaatgatc cgctgttctt ctgtcaaata aaagatcacc gggcgataat
    26461 tgtcaccgcg atcctcgaat tgtccgaaag cgtcagttgg atcagtttgc tgccagtaaa
    26521 gttctactaa ttgttcatat gaaatcaatg ttggatcata gataatctcc actgcttctg
    26581 tatgtccagt cgtttggctt tttacttgtt cataagtcgg atctggtaca tgccctccag
    26641 tatatcctga catcactgta tggataccag gaagcgtgtc gaaaggctgg atcatacacc
    26701 agaagcagcc tcctgcaaat attgctcgtt ccattatgat tccccctcta atactactca
    26761 tccgatgatt ttttattttc ttttgtcttg ctttcagtac tgctggtgct agttttgttg
    26821 gtatttgagt tgtttgaagc atcagaggta tcttttggca aatatagact aaaccgaatg
    26881 tcatcattta ctaagtcgat tttatctgct ttaatataca tcccgttttg cattcggaat
    26941 tgatccaacc taagcatgat agtcagatca tctgtattga cttcgatcca atctggtaat
    27001 ttatagtttc tcttgatcat attcatcaca tctttgattg gcaaactcaa tgttccgata
    27061 gaaagacttc tagcttttag ttggacattt ccgttttcca tcacatacgg atcaaaatat
    27121 aaatagaaat cgataggaaa acctagtact tcgaaagtac cattgagtag tgcttcattt
    27181 tccaaataaa atttatattc aatatcacta tctttttgat actcactaag gaaaaagctg
    27241 atgatttgat tgactttttc tttatttgaa ttgatcgtta agacaggatc tccttgtctt
    27301 tccgtaagag ctggtatttc tgggagttct ggttcccgat tagcaaaaat acggctgcct
    27361 aaaaatacgg tcgaaccaag tactacccca agaaggataa ggaaggcgaa tttccagtaa
    27421 tttgttttct ttgttttgtt tgaagatacg tcagatcttg ttttcatgtt tattgatcat
    27481 cctccttctc taaccattgg ttttgtgtct cgatcagctg atctctcact gcatttgcca
    27541 tcaattgata acctaaatta tttggatgga aatgatcttc ttcatagagc acattatttt
    27601 tgatgccatt tagattttct gtcgtgctag ttgtttgatc tgttccttct tctgtgacac
    27661 ctacttcctg attcaatcct tgataaagca aatcattgat tgggataaag tagcagttcg
    27721 gcattttttt tgtcaccgtt tctgttcctt tgttccaatt gttaacaatt gtctgcatgt
    27781 cagtgatctc aggaaagttc aaataaaatg gattgtagat gcctaaaatg taaataggtg
    27841 cggttttatt gagggatcga aattcttcca atagttctgt gacattttcc tgatagtttt
    27901 tcagtggctt tttaaaggaa ttgaccgtta acccgaataa attattttgg ataactttca
    27961 tcaaatcatt accgccaaca gtcagtgtga taaaatcagc tgttttgata ttgtttcgaa
    28021 tttcttcttt tgtttttact cgctttaaga tctggtcact tcgttcacca tttacaccat
    28081 agttttctgt ttcaaccgcg gtcaaattat aacggtcttt tagatcattt gcgacaaggg
    28141 gaacgaatcc tccttgcttg gtttgatctc ctactccttc agtcagcgaa tctccgatag
    28201 ctatgtagtg aagtttttct tttttatttg gatcttctct cacagtagtt actggtttca
    28261 ttagtgggcc agctttcggt atagaagcag ctaaacctgc atagatgatg atcgcaatta
    28321 ataatgggaa caaaacgagg atcaaatgtc gtttcgttaa tttcattttt tcacctcttg
    28381 tattcgattg gttctaatgt tatcaaaaat tttatcaaaa aggtagtctt tatgaaaaaa
    28441 gaaaacaatt attttcctaa ttttataaag aaaaagagaa taagctgcaa gcctttcagg
    28501 ctgagggctt atcctctttt cgactaatct acataataca tgattgcaaa cgcgtcttta
    28561 ccagtatgcg tagcgataac cggattcgta tgcagtacag ggatatgcat gtccgggaat
    28621 aattcttgca aaccctcttt gaattcttgc gccaattctt ttgcatccgc atgtgaaata
    28681 ccgatttgtc gcacatttgg caattctttc agttcatttt tcaaattatt aaaccattta
    28741 tcgaacgttt tctttcctcg ccccttagtt acagggatta attcagaatg ggcgaaattc
    28801 atcaccacgc gtatgttcaa aacactagac agcaaaccag ttgttcggct gattcttcca
    28861 ccttttacca agttatctag tgtggatatt ccgatgtata attttgtatt gtcttgtact
    28921 tttttgactt cttcaaggat tttctctact gttttacctt cttttgctaa ttcagctgct
    28981 cgaattacct gaaaagataa tccttggtca gtggtatcac tgtcgataac cgttactttc
    29041 gtttttgtta gattactggc ttgtcttgct gcttctactg ttccactcaa gccttttgtc
    29101 atatggatcg aaatcacttc actgccgtct tctcctagct catcatacat cgagatgaat
    29161 tctccaattg gtggttggct tgttttgggc agattttttg ctttcgccat catttccata
    29221 aatctttcgc cgtctagttg gtcatcatcg ggatatactg ttccgtcgat catgatggat
    29281 agcggcatga cacgaatgcc taaagcatcg cgtacatttt tttccatcgt acatgaagaa
    29341 tctgttacga tttttacatt tgtcattatt ttctctctct ctttctttaa caagatgcct
    29401 tattcatgtt aaactacatg taagacaatt tctattttta gtataacaga caaataatga
    29461 tttttcatta attacaccta gtaaaggagc cgttttcatg gaaaaaacga aatttaatcg
    29521 aacgtatgaa atattaaatg aagtgtttaa tgcagtcacc catggaattg ggactggatt
    29581 gagtatcgcg ggactagtgg ttcttttagt aaaaggtgcc cacttgcatt cctccctcca
    29641 tattgtctct tatgctatct atggatcgat gatgattctt ttatttttaa cgtctacttt
    29701 gtttcattca ttgattttta caaaagcaaa aaaggtgttc caagtattcg atcatagttc
    29761 gatttttctt ttgattgcag gaagttatac tcctttttgt ttgctgagta tccgaggatg
    29821 gctaggttgg actttatttg tattaatctg gttgtttgcg attcttggca ttatatataa
    29881 agcgttgacg ttgcataaac gggagagagt atcaaaagta tctacgatca tctatatttt
    29941 tatggggtgg ctctgtgtcg tggctgctgt tcctctttat cactctcttg gaatgactgg
    30001 tgttattttg atggtagcag gcgggctttc ttacacgata ggcgcattct tttatagctt
    30061 gaattctatc cgctatatgc atgttgtttg gcatttgttt gttatgttag gtgcaggttt
    30121 tatgtacttc tctgttttat tctttactta ataaaaaaaa taaagctatg gatgggacag
    30181 ctctaaataa cagctagtct atccatagct tttttatatc gtcaattcgc ctgtcccgct
    30241 ttttacagga ttctcattac gctgatacgt ttcaaattga tgcggataac gatttttttc
    30301 atccatttct ccttgactag tattgatcag tgaccaatca gaccagtcaa caggtggaaa
    30361 ataagcatct ccatcgaata catgatggat gactgtacgg tataatatcg tacaaaatgg
    30421 cagaaattct tgataaacag ctgaccctcc agcgatgaaa aagataccgt ctgtttcttt
    30481 ttccagagca agcacgtctt ccacactatg catgacatgc acgccttctg ctttatagga
    30541 agaatctctc gtcaaaacaa tcgtctgacg attcggcaac ggacggctac ccatcccttc
    30601 gaatgttttt cgtcccatca ctagtgtatt tgcttctgtc atttgtttga agaatttcag
    30661 atcatttggc aaacgccaag gaagacggtc ttcttttcca atcaatccgt tttcatcctg
    30721 tgcccaaatt gcagctaaca ttttctcatc ctttctgatt ctaaacagcg ataggagctt
    30781 tgatcgccgg atgtgggtca tatccttcta attggatatc ttccatctca aaatcaaata
    30841 ctgactgctt ttcctgattc aaaactaaag tcggaaatgc gcgtatttct cggctcaatt
    30901 gttctttcat ttgttcgata tgattgatat aaagatgagc atctcctaat gtgtgaacaa
    30961 attcgccaac cgctaaacct gtttcatgtg caattaggtg agtcagcaac gcataacttg
    31021 caatgttgaa cggaacgcct agaaacacat ccccactgcg ttgatacaat tggcagctta
    31081 gccgtccctc ttgaacataa aattgaaaca tcgtatgaca aggaggcaaa gccatgctag
    31141 gaacatcttc cggattccat gcagaaacga tcaatcttct agaatcagga gtctttttga
    31201 ttgcttcgat cacttgtttg atttgatcga taaagccacc gtcttttgtt tcccagtgac
    31261 gccattgata gccgtagatg tgtccaagat cgccgtatgt ttcagcaaag gaatcatcgg
    31321 ttaggatctt ctcgcaaaaa agcttgctct gctttttata ttcttcattg aattcaggat
    31381 ctgtcaaaca tctatggcca aaatcagtca tatctggtcc attatagtct ggacttttga
    31441 tgtagcgttc aaatgcccat tcatcccaaa tatggttttt attttgtaat agatagcgga
    31501 tattcgtatc tccttttaaa aaccaaagca attcgctttt gatcaatcca aaaggtactc
    31561 gtttcgttgt taacaaagga aacccttttt gcagatcaaa ccgcatttgg tatccgaata
    31621 agcttaatgt gcctgtgcct gttctgtctt ctttacgatg cccttcttcc aacaattttc
    31681 ttcctaagtc aagatacgct tgttccatcc tttttcctcc taatcttcta cccattcact
    31741 caagtattcc caccgtgcca ttttttcttc aagttgtgct tctgtttcag atacgtcgtt
    31801 ttgcaattct tgtaatcgag tgaaattatc tccttgatga ttcatctctt cttggagcaa
    31861 tgagattttt tcttcaagtt ctgcaatctc atcttcaatc gtttcccatt ctttttgttc
    31921 catgtaagat aatttcttct tttcagcagg ttccttgctc tgtatttttg gtttcgcttt
    31981 ttcagcaggc tgctgggtct ctttttgctt cagtaaataa ctggacatgt ttccgtaata
    32041 aagttcttgt tttccgtttc cttggaatac taataactta tctgctacct tgtccaagaa
    32101 ataacggtca tgggaaacag tgatcacagc acctggaaaa cttctaaaat aatcttccaa
    32161 aatcgtcaat gttgctatgt ccaaatcatt ggtcggttca tccaataata aaacattagg
    32221 ttgctgaatc agcagtttca acaaaaataa ccggcgtttt tctccgcctg aaagtttgcc
    32281 tatcagtgtc ccatgcataa atcttggaaa taaaaatcgt tcaagtaatt ctgctactcc
    32341 gatttgactg ccatctgctg tttttgcttc ttcagcagct tcttgtaagt aagcaatcat
    32401 ccgtttatct ggtgccattt cttcattttc ttgtgtataa tacgcaagat gaaccgtttc
    32461 accgatagac attgtaccgc tatccagggg aattctgcca gctagaatat taagcaatgt
    32521 cgattttccc gcaccatttt taccagtaat acctagtctt tcccgagatt gaatcaataa
    32581 atctaaatgt tctagcagtg tttggtcatt tatacggtaa ctgccatctt tgatttccag
    32641 tacttttttc cctaaacgtt gtgtcgctag gttcagctct aaatcatctt cttggtttac
    32701 ttggtacaag ttctccttta gatcttcgaa acggttgatc cgtgcttgct gcttggtgcc
    32761 acgtgcctgt acgccagccc tcatccaagc taattcctgt ttataaagcc gcttgcgctt
    32821 ttcttcttgt tctacttcta cacgatcacg ttctgctttt tctaagacgt aagcttcata
    32881 atttccttta tactcgtata attttccaaa tgaaagttcg aagattcggt ttgctactct
    32941 atctagaaaa taacgatcgt gggtaaccat caatagtgcg ccacggtatt gtttcaaata
    33001 gttttccaac cactcgatcg cttcataatc taaatggttt gttggttcgt ctagtaatag
    33061 taaatcgggt tcatcaatca acacttgcgc cagactaact cgttttttct gaccacctga
    33121 taaagtactg atttttttat ctaattcact gattcctaat ttttgcaaaa taatctttgc
    33181 gttggtatct gtagtccaag catcttcttt attcatttgt tcttctgctt tagcataacg
    33241 tttttgcaca tcagggtctt ctccgttttc ccctagttcg atcaatgctt cctcatatgc
    33301 tcgaacagtt tggatcaagg ggctgtttcc ttgaaagact gcttggagaa cagttaattc
    33361 atcggaaaat tcagctgctt gagaaagata accaatacgg taatcagttg gataaaacac
    33421 tgtttgccga tcaccgtcgc tgctatcgat accggcaata atatttaaga gacttgtttt
    33481 acccgtcccg ttcgtcccaa tcaacccgat acggtctttt tcgtggacca aaaaagaaat
    33541 ctggtcaaac aaatcttttt caccataagt ttttttgagg tcagttactt ttaattcttt
    33601 caacatgttc cctccttatc ttggatattg tatcataaaa atagtgaact tcaggaaaat
    33661 ttttttggta tttgttcttt ttgtgttctc aaaaaaagaa caggaccgat tcgatcctgt
    33721 tctgatatgt tttgtttttt ataaaacttg aaaattttta c
//
LOCUS       DAIGQM010000027        33288 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.027, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000027 DAIGQM010000000
VERSION     DAIGQM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.027"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            134..409
                     /locus_tag="NOA48_001285"
     CDS             134..409
                     /locus_tag="NOA48_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCI0789557.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            415..1182
                     /locus_tag="NOA48_001286"
     CDS             415..1182
                     /locus_tag="NOA48_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCI0789558.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1350..3179
                     /gene="typA"
                     /locus_tag="NOA48_001287"
     CDS             1350..3179
                     /gene="typA"
                     /locus_tag="NOA48_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCI0789559.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3440..5212
                     /gene="recQ"
                     /locus_tag="NOA48_001288"
     CDS             3440..5212
                     /gene="recQ"
                     /locus_tag="NOA48_001288"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCI0789560.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5326..5628
                     /locus_tag="NOA48_001289"
     CDS             5326..5628
                     /locus_tag="NOA48_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCI0789561.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5631..6794
                     /locus_tag="NOA48_001290"
     CDS             5631..6794
                     /locus_tag="NOA48_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0789562.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6820..10248
                     /locus_tag="NOA48_001291"
     CDS             6820..10248
                     /locus_tag="NOA48_001291"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCI0789563.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10269..11393
                     /locus_tag="NOA48_001292"
     CDS             10269..11393
                     /locus_tag="NOA48_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789564.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11383..11820
                     /locus_tag="NOA48_001293"
     CDS             11383..11820
                     /locus_tag="NOA48_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0789565.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11804..12142
                     /locus_tag="NOA48_001294"
     CDS             11804..12142
                     /locus_tag="NOA48_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCI0789566.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12261..12821
                     /gene="rsmD"
                     /locus_tag="NOA48_001295"
     CDS             12261..12821
                     /gene="rsmD"
                     /locus_tag="NOA48_001295"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCI0789567.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12818..13309
                     /gene="coaD"
                     /locus_tag="NOA48_001296"
     CDS             12818..13309
                     /gene="coaD"
                     /locus_tag="NOA48_001296"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCI0789568.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13299..14342
                     /locus_tag="NOA48_001297"
     CDS             13299..14342
                     /locus_tag="NOA48_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCI0789569.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14501..15229
                     /locus_tag="NOA48_001298"
     CDS             14501..15229
                     /locus_tag="NOA48_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCI0789570.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15345..15590
                     /locus_tag="NOA48_001299"
     CDS             15345..15590
                     /locus_tag="NOA48_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0789571.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15587..15805
                     /locus_tag="NOA48_001300"
     CDS             15587..15805
                     /locus_tag="NOA48_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCI0789572.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15941..16480
                     /locus_tag="NOA48_001301"
     CDS             15941..16480
                     /locus_tag="NOA48_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCI0789573.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16473..18746
                     /locus_tag="NOA48_001302"
     CDS             16473..18746
                     /locus_tag="NOA48_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCI0789574.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18784..19830
                     /gene="holA"
                     /locus_tag="NOA48_001303"
     CDS             18784..19830
                     /gene="holA"
                     /locus_tag="NOA48_001303"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCI0789575.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19919..20173)
                     /locus_tag="NOA48_001304"
     CDS             complement(19919..20173)
                     /locus_tag="NOA48_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCI0789576.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(20573..20842)
                     /locus_tag="NOA48_001305"
     CDS             complement(20573..20842)
                     /locus_tag="NOA48_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789577.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(21312..21767)
                     /locus_tag="NOA48_001306"
     CDS             complement(21312..21767)
                     /locus_tag="NOA48_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCI0789578.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(21905..23833)
                     /locus_tag="NOA48_001307"
     CDS             complement(21905..23833)
                     /locus_tag="NOA48_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0789579.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(24030..24863)
                     /locus_tag="NOA48_001308"
     CDS             complement(24030..24863)
                     /locus_tag="NOA48_001308"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCI0789580.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(25055..25759)
                     /locus_tag="NOA48_001309"
     CDS             complement(25055..25759)
                     /locus_tag="NOA48_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0789581.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(25782..26408)
                     /locus_tag="NOA48_001310"
     CDS             complement(25782..26408)
                     /locus_tag="NOA48_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0789582.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            26734..29109
                     /locus_tag="NOA48_001311"
     CDS             26734..29109
                     /locus_tag="NOA48_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCI0789583.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(29133..29624)
                     /locus_tag="NOA48_001312"
     CDS             complement(29133..29624)
                     /locus_tag="NOA48_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCI0789584.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            29811..30731
                     /locus_tag="NOA48_001313"
     CDS             29811..30731
                     /locus_tag="NOA48_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0789585.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            30885..31229
                     /locus_tag="NOA48_001314"
     CDS             30885..31229
                     /locus_tag="NOA48_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCI0789586.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(31419..31919)
                     /locus_tag="NOA48_001315"
     CDS             complement(31419..31919)
                     /locus_tag="NOA48_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789587.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            32447..32530
                     /locus_tag="NOA48_001316"
     tRNA            32447..32530
                     /locus_tag="NOA48_001316"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32481..32483,aa:Leu,seq:cag)
     gene            complement(32854..>33288)
                     /locus_tag="NOA48_001317"
     CDS             complement(32854..>33288)
                     /locus_tag="NOA48_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0789588.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11010 a         5771 c         6783 g         9724 t
ORIGIN      
        1 aaaaatcagt tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa
       61 atatgacaac ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat
      121 aggagagttg aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga
      181 aatggtcatt gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa
      241 caatgaagct tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga
      301 ggaaaaacga ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt
      361 gcagcaagca aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa
      421 cagatgattg atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct
      481 caacaaacat taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat
      541 cgaaacatcc agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata
      601 ttggcagaag aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc
      661 gatcctattg atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc
      721 gctgtttatg aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa
      781 cttttttggg gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca
      841 gcaaataaat ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat
      901 aaatatggaa tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct
      961 ggtcttgaac tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc
     1021 ccttgggatt atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt
     1081 ctttttggta ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt
     1141 gcatatgcag aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat
     1201 tcacaaaaat gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta
     1261 ctatatttca tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata
     1321 aagaaccaat aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg
     1381 caattattgc ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat
     1441 cagatacatt agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag
     1501 aaaaagaacg tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc
     1561 gcgtaaacat catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca
     1621 tgaaaatggt tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa
     1681 cacgttttgt attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca
     1741 agattgacaa accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca
     1801 tcgaattagg agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa
     1861 atggtacgtc aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt
     1921 ttgatacaat tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat
     1981 tccaagtttc attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat
     2041 ttagaggaac aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta
     2101 agaaattccg tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag
     2161 aagcaaaagc tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa
     2221 cagttactcc tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat
     2281 tgcaaatgac tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa
     2341 ccgctcgtaa gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag
     2401 ttgaaccaac aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt
     2461 ctatcttgat tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag
     2521 ttattgaaaa agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata
     2581 caccagaaga atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc
     2641 aagatatggt ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg
     2701 gtttgattgg ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc
     2761 atacttttga ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg
     2821 cgcttgtttc gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac
     2881 gcggtacagt cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa
     2941 acagccgtga taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac
     3001 ggtctgctac taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag
     3061 aatctttgga attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct
     3121 tgagaaaaca aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat
     3181 ctgtaaaagg atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg
     3241 tccaactctt ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc
     3301 cgaaagacgt ttaaaagact tttaaaaaac ttatttctag agagtttttg tttcataata
     3361 agataatgtt tcacgaaagg agatcaactt gtccttcgaa gaaaatcgaa gtaaaatggc
     3421 aagagaaagg agcgggaaga tgaacgactt attaaaacaa tactttggct atgatgagtt
     3481 tagacctggt caaaaagaaa ttatccagaa agtcattgat caggaaaatg tattaggaat
     3541 catgcctacc ggaagtggga aatcaatctg ttaccagctt ccagctttac tattagatgg
     3601 gcttactgtg gttgtgtccc ctttaatctc tttgatgaag gatcaggtgg acgcggcgaa
     3661 tcaattaggt atacccgcca cttttatcaa tagctcgtta gatggttacg aaacagctag
     3721 acgcttccaa gaaatcgata gacagcagta ccgtttactt tatatcgctc ctgaacgttt
     3781 tatcatgccg gattttatcc aagcaatgaa gcgatggaac gtccgtatga tcgctattga
     3841 cgaggcacat tgtatctctc agtgggggca tgatttccgc ccaagttatt tacagatggc
     3901 gaaccagcta gatcaactgc caaatcgtcc tgtaattgtt gctttgacag ctacagcgac
     3961 tgtgcaagta gctgctgaca taaaaagact tttaaaaatt ccagaaaaca accatattca
     4021 gactggtttt gaacgagaaa atctacgatt tcaagtaatt aaagatcaaa aaaaagaaca
     4081 atatctaatc gaatatttaa agatcaacaa aaatcaatct ggtatcattt atgcagcaac
     4141 gagaaaagaa gtagaccgtc tctatcattt gcttaaaaaa ttcgattttt ccgtgggtag
     4201 atatcatggt ggtctaaatg agaatgagcg aacagaaatg caagaagcct ttttatacga
     4261 tcgcttgcag ctgattgtag cgacaaatgc atttggtatg ggtataaata aaagcaatgt
     4321 ccgttttgtt atccattatc aaattcctgg ctctctagaa gcatactatc aggaagctgg
     4381 tcgggcggga agagatggtc tttccagtga agccatcctg cttttctctc ctcaagatat
     4441 ccaagtccaa aagtttttta tccagcagtc ccaaagagaa gaagggcaaa agcaaaaaga
     4501 atatgaaaaa ttaaaagcga tgacagaata cgtgtatatt gagtcctgtc ttcagcaata
     4561 catcctaaac tattttggcg agacaagcag tccgtgcaac cgttgtggta actgtttaga
     4621 tgacagagaa atagtagaag taacgacaga agcacagatg gttctttctt gcttaaaacg
     4681 tatgggtgag aactatggta aacaaatgct gatgaaagtc ttagcaggat cgaaagaaca
     4741 aaagctgcaa gctttaggtt ttggacattt atctacctat ggactgatga aaaaccaatc
     4801 gcaaaaagaa acgatgcagt taattgaata tttgatatcg aatggctatc ttctgaccat
     4861 caatggtgag tatcctgttt tgaaagtaac agaaagaggg atacaagtat tgaaaggaca
     4921 agaatctgtt tatcgaaagg aacccaagaa agtccagcag ctatcggatg aagaaaccga
     4981 tacactattt gaagtgctgc gggaactgcg aacggatcta gcatcagaag caggcgttcc
     5041 cccgtatgtc gtattttcag attccacatt gaaagaaatg agccgaatac gtccatcaag
     5101 cagattggag atgcttcaga taaaaggagt tggccaaagc aagcttgata aatatggcga
     5161 agccttttta tctcggataa aaaatgcgga ctctaacgtt ctggataagt agaaagaacg
     5221 aatacgtaaa aatgaataaa aacaactggt taaatctgtt ttttttgctc cttatgaaaa
     5281 tcaaatatgt tataattaag gaattagaat gggaggtaag cacagatgga ttctttgtcg
     5341 aaaaaacttg cgatccaagt attaaatgat gaagcagaac ggatcaaacg attaatccga
     5401 aatcaaaaca acagtctctg tatctcacaa tgcaaagcct tcgaagaagt ggtagataca
     5461 cagatgtacg gcttttcccg gcaagtcggt tttgctgtcc gtataggagt aatcggaaag
     5521 aacgagggcc agctgatgtt aagtgagcta gaacgagaat tgaatcagtt atatagtgag
     5581 gtttaccaag aaatttatga taaaaaagaa gttggcaagg aggaatagac ttgcctaaga
     5641 aagtgaaaaa aaggcatcta ttagactata gcatcttgat tccctattta attttatgtg
     5701 tattgggatt gatcatggta tatagttcta cgtcgtatct attattagaa aacggacaaa
     5761 atccgtccgc atcagtcatt aaccagagta ttttttgggt gcttagcttg attgctatcg
     5821 cactacttta taaaatgaaa acagatgttt tgaaaaacca gcgtttgatc atggcagcca
     5881 tcgcagtttt gacgattttg ctgctgattg ttgtgttttt tggtaaggag atcaatgggg
     5941 cgaaaggttg gctgcaaatt gcaggattct cgatccaacc tgccgaatac ctaaaaatca
     6001 tttctatctg gtacctgtct ctgactttat ctaaaagaca aaacagtgta caaaaagatt
     6061 ttcttgggac tgtgaaacgt ccacttgcaa tggttatcgg acttactgca ttagtcgcta
     6121 ttcttcccga ttttggtaat gcggcagtta tctttttgat tattttggtt ctgcttttag
     6181 ccagcggagt caattatgtg tatactttga ttgtaggagt aggaggcttt tgtctaagta
     6241 cttttacgat ctggctgatc aatatcacaa acggaaagat cttacccgga cgtttacagt
     6301 atatctataa tcgatttgct atttaccaaa atcctttctc agacgaatta aataaagggc
     6361 atcaactagt caacggctac tatgccatgt tcaacggagg actatttggc aggggattag
     6421 gtaacagtat ccagaaaaaa ggatttttac aagaagcaca aaccgatttt atttatgcaa
     6481 tcgtagtgga agaactggga gtgattatgg ggattttgat attagcgttg ctattcttta
     6541 tgattgtgcg cattgtcctt gtaggtatcc gttcaaaaga tccgttcaat tcgcttttgt
     6601 gcattgggat cggcgcaatg tttttgatcc aagtatttgt caatcttgga ggaattactg
     6661 gcgttattcc tttgacaggg atcacgttcc catttttaag tcaaggaggc tccagtttgc
     6721 tgatgctttc gatttgtgtc ggctttgtcc tcaacatcag tgcggatgaa aaacgcaaga
     6781 gcttaggttt ataataaaaa aagatgtagg agtggttcga tgaaaaaagt tttagttgct
     6841 aacaggggtg aaatcgctgt acgtgtattt cgtgcttgta cagaattagg aattaaaact
     6901 gttggaatct atgcagaaga agatgaatat tccgtacacc gtttcaaagc ggatgaagca
     6961 tatttagtag gacaaggaaa aaaaccgatt gatgcgtatc tagatattga agggatcatt
     7021 tctatcgcga aagaatgcgg agctgacgct attcatccgg gttacggtct tttgtcggaa
     7081 aacttgaatt ttgcgcaacg gtgcgaagaa gaaggcatca tttttgttgg acccaaactg
     7141 catcatttag atatttttgg agataaaatc aaagcaaaag ctgcagctat cgaagcgggg
     7201 attgcttcga ttccaggcac agatggacca atcgcttcta tagacgatgc cttggagttt
     7261 gcgaaacaat acggttatcc gattatgatc aaggcagctc taggcggcgg cggacgcggc
     7321 atgcgtgtag ctcacgatga aaagagtgca agagagggct acgaacgtgc gaaaagcgaa
     7381 gcaaaagcag cctttggtag tgatgaagtg tatgttgaaa aatacatcgc taatcctaag
     7441 catatcgaag tacagattct cggggatacg catggaaacg tcatccatct ttttgaaaga
     7501 gattgttctg ttcagcgccg tcaccaaaaa gtagtagaag tagcgccttg tgtctctatg
     7561 aatgaacagc aacgtcaaaa aatctgccag gcagctgtcc aattgatgaa atatgtcggg
     7621 tatgtcaacg caggtacagt agaatttctt gttgaaggag atgattttta ctttatcgaa
     7681 gtcaaccctc gcgtccaagt ggaacatacg atcacagaaa tgattacaga tattgatatc
     7741 gtaacaacgc aactgttgat tgctcaaggt ttggatctgc ataaagaaat cggattgcct
     7801 cagcaagaag gaattaaatt aaatggttca gccattcaat gccgaatcac tacagaagac
     7861 ccgttgaata actttttacc agacacaggg aaaatcgata cgtatcgttc acctggtggt
     7921 tttggcgtac gtctggatgt cggaaatgct tacgcgggct atgtagtgac accgtatttt
     7981 gattcattgc tagtaaaagt atgtacgcat ggtgctacct ttgaaacagc cattcagaaa
     8041 atggaacgtt gcttgaaaga atttagaatc cgtggagtga aaacaaacat tccatttatg
     8101 ctcaatgtca tcacacatcc tgaattccaa tcaggaaatg caaaaacaac cttcattgat
     8161 agtacagcaa cattatttga atttcctcga ctacgagacc gcggaaacaa aacgatgaaa
     8221 tatatcggtg aaattactgt gaatggtttt ccaggtatcg aaagtggcga aaaaccattt
     8281 tatgaagaac cacgtatgcc taaagatcta atcacaagaa ctgattacgt aacggctaag
     8341 aatgtattag atgcgaaggg tgccgatgct ttggtcgaat ggatcaaagg acaggaaaat
     8401 ttgttgttga cggatacgac atttagagac gcccatcaaa gtctgctagc aactcgtgtt
     8461 cggacaaagg atttcaagca gattgcacgt ttgactggag aaggtcttcc tgaactcttt
     8521 tcaagtgaga tgtggggggg agcaacattt gatgtggctt accgcttttt gaatgaagat
     8581 ccttggcaac ggttgagaaa aattcgttct ttaatgccta atacgttgct gcaaatgctt
     8641 ttcagaggtt caaatgccgt tgggtattct aattatcctg acaatgtatt ggtggaattt
     8701 gtcaaagaag cagcagcgca aggaatcgat gtatttcgaa tctttgatag tttgaactgg
     8761 actccacaaa tggaaaaaag tatccaagct gtacgggata ctggtaaaat cgcagaggca
     8821 gctatttgct atactggcga tatcaacgat ccaagtcggg caaaatacaa tgttcagtat
     8881 tataaagaca tggcaaagga actagaacaa ctgggtgcgc atatcattgc aatcaaagat
     8941 atggctgggc tgcttaaacc gcaggcagct tatcgtttga ttagtgaatt gaaagaaacg
     9001 acagatctgc caatccatct gcatactcat gataccagcg ggaatggaat catcacttat
     9061 tctgctgctt caaaagcagg agtagacatc gttgacgtgg caatgagtgc aatgagtggg
     9121 aatactagtc agcctagcat gagcagcttg tattatgcac tggtcaatgg tccacggctg
     9181 ccagaaatca cgattgaaaa tgcacagaaa ttaaaccatt attgggaaga tgtgcgcatg
     9241 tattacaaac cgtttgaaaa cggcttgaat gctcctgaaa cagaagtata tatgcatgaa
     9301 atgccaggag gacagtattc gaatctacag caacaggcaa aagctgtcgg attaggtcat
     9361 cgctgggatg aaatcaaaca aatgtatcat actgtcaact tgatgtttgg cgatatcgtt
     9421 aaagtaactc catcatctaa agtagttgga gatatggcac tatttatggt ccaaaatgat
     9481 cttacagaag aagatattta tgaaaaaggc gaaacactaa gtttccctga atctgttgtg
     9541 actttcttcc aaggagaact agggcaaccc gttggcggat ttcctaaaaa attgcaaaag
     9601 attattctta aaggcagacc tgcattgaat gaacgtccag gtcttttggc tgaatcagtc
     9661 gacttcaacg aagtaaaaaa agaattggca gaaaaaattg gctatgaacc aaaacaagac
     9721 gaagtattaa gctatttgat gtatccgcaa gtctttttgg actatcaaaa agcatataat
     9781 caatttggcg atgttacatt actggacaca ccaacatttt tccaaggtat acgtttgggt
     9841 gaaacaatca atgtacaaat cgaacgcgga aaaacgctta tcattcgttt agatgaaatc
     9901 ggagaacccg atatcgaagg gaatcgcgta ctgttcttca atttgaatgg acaaagacgt
     9961 gaaatcacta tcaaagataa ttcgatcatc agtacggtcc aaacccgatt gaaagctgaa
    10021 ccgacaaacc gagaacaaat tggagcaacg atgtctggtt ctgttttgga tgtattagtg
    10081 aaaaaaggcg ataacgttaa aaaaggtgat acgttgatga ttactgaagc gatgaaaatg
    10141 gaaacggcca tcgaagcacg ttttgacgga gaagtcgcac atgtatatgt gtcttcagga
    10201 gacactattt cgtctggtga ccttttgatt gaagtgactg agaaataata agcgaaaggt
    10261 ggggaaacat gaaaagactg ggtttgtttt ggctgattct gctattagtt attgtggcat
    10321 tctacatgga accagtcttg tttccgccaa aacttgaagt gaaggaaaac tctgatcaac
    10381 aaatatcaaa ccaaatgaca acgtggaaat accaggagct taaagcaact ggtttttcta
    10441 cttatatcgg aaaaccgatc gatcagctgg aaaaggattt tggccaagcc tatgatcgat
    10501 taactagcgg atttggtttt gaaacaagat attatgaaaa taaagctagt catctcacat
    10561 ttgaagcgaa catccaagac agcagagtca caactgttaa agtactgcaa acagggcctg
    10621 ctgatatcgc gccgttttat ttagggatga cgatgcaaga tcttacgaaa atcactacta
    10681 tctatactaa tttcactttt gagtaccatg atacagaagt tggaatcgaa ctaatggaag
    10741 aggatatgaa ttatcgtccg ctaattgctt ttgataacga cacttttgct attttatttt
    10801 ttgatcaaac aacaaacggc ctattttcag ttgtgtattt agataaagat agtcttttga
    10861 aactattgcc atatcaagtg tttggtgaag gccttccaca ttatcaagca gataaatcgg
    10921 ctgattggga atcaatcaat cgcgttaaag aacgaaaaag tacgacttta ttaaatatgc
    10981 ttagaagaga agacgaactt cccatataca atcaaacact tgcctttcaa aaccacagtc
    11041 agctgctact acatgatttt ttgacaaggc ctgaggaaat attgtcagag gaacgtatgg
    11101 ctgattggca aaaatcgcta ggcagtgctc aaacgacagt gaaattctca ctgacgaatg
    11161 atgaattgga gaagttaatc agtaaacaaa aattagaaaa tactagtggg ctatttattc
    11221 atccggcgat tgacgctact ttttcgtttt tatattggta cagcgatcct tacaaccatg
    11281 accgtttcat ggacccggga acggattctg taggcattgc tttttctaaa gaaaatatgt
    11341 tagtcttatt gcaagaagaa aacggagaaa gtagtgatag cagtgatcgt taacgaagag
    11401 ctgtttcaac tggaggatca atgcctccaa gtcgctgaaa tgataaaaaa gagtaaaacg
    11461 atggcttctt atcttgaaca taaacagtca atggaagaat ctgcaaaagt ttgccagttg
    11521 aaagaagcgt tcttgtctaa gaaagaagca tttgaaaatg tagcggcata tggtgagtat
    11581 gcacctgatt atcgtgaaaa aaaacgagct gttcgaaaag caaaaagaca gcttgatatg
    11641 gatgagcatg ttgcagcttt ccgatatagt gaaacacagc tgcaaagtct gttggatcaa
    11701 attgtccaag tacttgccga agaagtttct aatgaaatca aagtagatgc aggtagcccg
    11761 ttttttgaaa cgaaaaaaca ctttggatgc ggaggtaatt gtcatgcaat tagacaatag
    11821 tgaatttgaa ataacaaaac gacgcgggct gatcgtatgg gtctacagct taaaacaatt
    11881 aaagaatctg aaaaagttcg gcttgttgca ttatgtctca agaagaatga aatatgtcgt
    11941 gctttactta aatgaagaga cattggaaga aacagaagaa cgaatccgta aattacattt
    12001 tgttcgaaac gtagaacgtt cttaccgacc ggatatcgaa atgaattttg ccgaaaaaat
    12061 aggaaacaaa acagtattaa aagacgaagg tttcgaaatt gaagagctaa atacagaaat
    12121 ccgattagct gaacatcttt aaaaatctct tatgagcagt ttttaaataa aaaataactt
    12181 ggataacgat cgatttttga tcattgtcca agtatttttt tggtatacta gtaccagtac
    12241 catttctaag gagtgagtag atgcggataa tatcaggaaa ttatggcggg cgccgtttaa
    12301 aaagtttagc aggggcgaac accagaccaa ctacagataa agtaaaagaa tccatattca
    12361 atatgattgg accatatttt gatggagaga cagtattgga tctgtttgca ggaagcggtg
    12421 gtttagctat cgaagcagta tctagaggct gcagtcatgc ggtatgcgta gacaaaaatt
    12481 accaagcgct aaaaatcatc aaagaaaaca tcgaaattac gaaagaacca gagaaattta
    12541 ccacaataaa acttgatgcg gacaaagcaa tcgaacggct agcagcggag aaacaacaat
    12601 tcgactactt gtttcttgat ccgccatatg caaaacaaaa aataatcgat caaatccata
    12661 aaatggaaga actgggactt ttttctaaaa ccgcagttat cgtatgcgaa acggataaaa
    12721 cagtcgaatt gccagaaact gtggctggat tccatcaaat aagaaaacag atttatggca
    12781 taacggccgt aactatctat agaaaagagg gaaatcaatg aaacgtgcat tattcccagg
    12841 aagttttgat ccttttacaa aaggtcactt agatacggtg gaacgtgcgg ctaaattatt
    12901 cgatgaggta gtaattggtg tttttatcaa tacttcaaag aaaagtttgt ttcccccaga
    12961 agaaagaatg acattgatca caaaagctgt ttctcatctt cctaatgtaa aagtcatgca
    13021 tcaagaaaat caattgacgg tagaaacagc aaaagagatt ggtgcagatg cgttgatcag
    13081 aggcatacga agtatcaaag actttgaata tgaacgagag attgctcaga tgaatcatca
    13141 tctatatgat gaattggaaa ctgtcttctt attagcaaaa ccagaatata gtcacgtgag
    13201 ttccagtatt ttaaaagaag tactgcactt tggcggagat gtgagcagct acttaccgcc
    13261 agtgatcaac gaagctttag ctggaaagcg tgaatcaaat gaaagctaaa caatggttga
    13321 aaacagtact gattatcata tttggaatgt tgatcattgg atttgtagta gttcccttgc
    13381 cgtattatgt agaatcaccg ggagccacga tcgatctgaa agaactaatt acggtcaatg
    13441 ataaggaaga taaaggttct gggtctttct ctcttacctc tgttggtatc aggcaagcta
    13501 caggtttctt agctttaaaa gctaaaatga ccccttttga agaattgatc agtgaagaag
    13561 aattgactgg tggggcgaca aatgaagaat ataatcaaat gcaacagtat tatatggatt
    13621 cttcccaaaa tgcagcaatc gaacaagcgt taaaacttgc agacaagcct tataaaatgg
    13681 aattcaaagg cgtatatgtc atgagtgtag agaaaacatc gaatttcttt ggcaagcttt
    13741 cagttggaga tacagtaaca aaagtagacg ggaaaagctt tcaaagtaca gaagcattta
    13801 tggattatgt aaaaagccaa aaagttggac aaacaatcga aatcagttat ttgcataatg
    13861 gtgaagaaaa aacagcttct ggtgatctga tcgagttacc aacagataaa aaggcaggaa
    13921 taggtatcac gcttactgac cataccgaga tcgaatcaga tacagatgtt cgtattaatt
    13981 ctggctctat cggtgggcca tcagcgggat tgatgttcac tttagaaatc tatgaacaag
    14041 tcactggtaa aaacttgcga catggtaagc aaattgcagg aactggaacg atcaacagtg
    14101 aaggagaagt tggccgaatc ggaggaatcg ataaaaaagt ggcaagtgcg gataaagctg
    14161 gcgtagagat tttctttgca ccagatgata cgatttcaga cgatgttaag aaagaatatc
    14221 ctgaaataaa aaccaactac gaagaagcaa aagctgccgc taaaaaattg aattcctcaa
    14281 tgaaaatcgt accagtaaaa acagtacaag aagcgcttga ctatctagag aaaatgaaat
    14341 gaaactaaat aattaaagag gggttgtgac acgagttctg tcacaacccc tctttttcgt
    14401 caaaaatctt cacgataaaa ataaaaacaa aagaaaaaat tgacgtaatt agatgttgaa
    14461 gggacgattt tgccagagct cactgtttct tcaattttaa atgaaaggag taatgaatga
    14521 tttttactgg tcattctttg aaaaaagaac aatgatagaa aaaatcagca agaaaatact
    14581 agcttcaccc aaattgatca tttggatgtc tatgatagtt cttatctttt gtatcgcaag
    14641 tggtttttta ttatcaaatt tgctatttta tagagaaaca gaagagactg ctgcaaaaga
    14701 aatactttct tcgtttagtt ccagtggaga agatccatca gctgaaggaa acgatgtaga
    14761 agaggatgct cgtccaaagg tcatgtacac cgatatcaaa ggaagtgtga aggagcctgg
    14821 tatctattcc ttttcttcag aagaacgggt ctatgatgta ctaaagcgtg caggtggatt
    14881 attagaagaa gcggatagcg atcgaatcaa cttttctgcg aagatagaag atcagcaagt
    14941 cctatatatc cctgctgtag gtgaagagct gccagaacat cttgatcagt tggcatcctc
    15001 ggaaggaaaa cagcctacag cagattccga gcctcccaaa ataaatatca atacagccac
    15061 tccatcagaa cttcagcaga ttcctgggat cggatcagtc aaagcgcaag aaatcattcg
    15121 atttagagaa gaaaacggat ccttccagaa agtggaagac ctgcaggaga tttctggtat
    15181 cggtgaaaag acagttgaaa aactaaaaaa cttcgttaca attaaataga atgattcaaa
    15241 atcgactggc acgagcaata aatggacgct aatggatact aagaataatc caattctaag
    15301 agcttggcag gacgaggagg tagtattttt ggataggaaa tagcttgatt gttcgcaaag
    15361 aaacattaaa aaaaccaatg ctgaatgtct atctccaaaa taaaatatct gggattcata
    15421 ttatgaatac ggctgtcagc ggcaataaca gtcaagctct acgagaacgc tttgccaaag
    15481 atgtacttag ctatacagca gataaagtat ttattctcat tgggacgaat gatctagcag
    15541 agcataaaca actttctaaa gaaacgtacc aaaaaatctg cagtggatga tagttcagct
    15601 gaaaaaagac tatagttctg atcatgcttt ctttatcacg ccaccagcag tcgatgagac
    15661 aaaacaaaaa tatcggaata acaagttgat caaagaatat atctctgttc tcacagaagt
    15721 agcaaaacgc catgattgtg aagtatcgat ttttatacgg aatttcttga acaaatggat
    15781 tcgaagaatt tttataatgg gctaatggat gacggacttc atttcggcag tgaagggtag
    15841 gatcttttgt cagacaggat gattcgttat atttaaagaa tattttgttt aagcaatgag
    15901 tactttttaa tcaacttgaa aaaacggagg aatataaaac atgttagaaa aatcttcaaa
    15961 agcatgcgat acgaataaag aaaaagttac tgataagtca cataatgaac gcattccttg
    16021 ggaccagtac tttatggctc aggcagtact gttatcttta cgtagtacgt gtacacgttt
    16081 agaagtagga gcgacactcg ttcgagaaaa aaggatcatt gctggcggct ataatggagc
    16141 agtcagtgga gatgtccact gcatagatga agggtgttac gtcgtggatg gacactgctt
    16201 gcgaacgatc catgcagaga tgaatgcact cctacagtgt gcaaaacttg gtatcccgac
    16261 ggaaggttca gaaatctatg tcacacattt tccatgtttg gcctgtacaa aggctttgtt
    16321 gcaagctggt gtgaaaggga tcaattatct ccatgactat cgaaatgatc cttatgccca
    16381 agcgttgatc gaacaattag gtgtatctgt acaccaagtt gctttagact cacagcattt
    16441 ttcaaaactt caaaatgaat taacaggaaa acatgtctag cgttttagaa aggcatgttc
    16501 gaaatcggtt gatttttccg gcaattacgt cgatgattat ctgtttgttg tattacactg
    16561 acaattgggg ttatcgtttg cttcttgccg gaattttttt atggttttcg ctaaaagaag
    16621 gacgttttat cgcgtacttg tgtattttgt gtagcataac ggtatccatt tcttataggc
    16681 tacaagagta ttcattttta gaggaaaaaa caacatctgc gcaaattact gtatttacag
    16741 atacgattcg tgcaaatggt aattttttga caatggaagg aaggttatca gagaataaac
    16801 aaaagctcca gctttcttat caagtaaaca cagaagcaga attgaaaaca tggcttaact
    16861 tccgaggaaa gggaatagaa ttgactgctg aaggcgagtt catctctcca gcaaaaaagc
    16921 ggaatcttta taattttgac caagaagctt acttcaggaa ccatagaatt tctggacggt
    16981 tccaaattca aaagattgaa cagatcacca tgcaaaatca ctggcgaaac tggcttcaga
    17041 gaaaaagagg atcttttatc tcctttgtcc aatctgaatt tccgcaaaaa acaagtgtat
    17101 atattaattc tttattatgg ggctataaag atgcaggatt cagagaacca gaagaaattt
    17161 ttagggagag tggtttgctg catctgttca gtctatcggg tctacacatc caattttatt
    17221 tagggtggct gtattattta tttcgacgta tcggatggcc actacacgtc agtattattc
    17281 cgttgagtct actaactatc tgttatgttt ctattgcagg aagttctatt tctgttttgc
    17341 gtgctagttt gctgttttta ttgcgattgc tagtcaaatt gctgaataag cattattcca
    17401 ccatggactt atttgcagtt gtcttttggc ttcttttact atttgatcct cgatttcttt
    17461 ttcatgcggg tggacagctt agttttttca tgagtttttt gtttatcctg atttcttttg
    17521 atggagattg gttgaaaaaa acggcctctc acgtcctgtt tactatgatc acgatgccgt
    17581 tgattgtatg gcatttttat gagtggccta ttttaggtag tctttttaca ttactgattg
    17641 caccggtatt caagtttctt tttcttcctg gtgtgttatt tctcacactc ttcaatcgct
    17701 ggctgccgga aactttactt ttgctgatag aagagggatt aatcttattt gagcgaataa
    17761 tcgatttttc ttcagggtcg tctctcatta taggacgttt gccccttgtg ctatctggga
    17821 tgtatatttt cggattactg atttgtatgg ataggttgaa agaacaacct gtgaaacact
    17881 tgttttatgt tggtcttttt tcttttattt ttttgacttt gccattttta cgcttttctt
    17941 caacgatcgc ttttatcgat gtcggtcaag gagacagtat ctttttgcaa agtccttttc
    18001 gaaaagaaac gattttgatc gatactggag gtcagttaca ctttgaaaga gaaaagtggg
    18061 cgcaaggtat gatacgtcct cctgctgaaa gaaatatcgt tccatatcta aaaggtcagg
    18121 ggataagtgt aatcgataaa ctcatcttga cacacgacga tacggatcat gtgggagaat
    18181 tacccacgtt atctcagcat tttactatca aaaaaattta tatcggttgg ggcgctggac
    18241 gaaatgagcc attacaaagg catttatctg aagctcaaaa aaatggtact gagatcattg
    18301 aaatcaaaca tggggacagg atcagcggtt attatgatct ttatgtattg actccttttg
    18361 aaaagggaga gggaagaaat gaagattcga ttggtctatg gatggaatat aacaataggc
    18421 gctttttatt tttaggagat ttgaatcaag caatggaaaa acaattgctt ttgatttatc
    18481 ctaatctgaa agccgatgta gtcaaattag gtcatcacgg tagccgtacg tcaagtaaca
    18541 cagattttct ttcccatatt gaagcaaaac atgggattat atcctgcggc gtaaataatc
    18601 gttatggtca cccgcacagc gaagtattgg agacactaga agaaaatcag ataaaaacat
    18661 ggcgaacgga tcaacaagga atgatcacct atcgctggca tccagttttt catcctcatg
    18721 ggctagtgga aacaatgata gactagtaat tctcatctgc tcatggtagg ataatttttg
    18781 aaagtggtga gtaatttgag tatacaagca gagttacaaa aaatacgtaa agaaaaactt
    18841 gcatcttgtt acttgatttt aggaacagaa aagtttctcc aagatcaagt tcggacagaa
    18901 attgtcaaaa aaatccaatt agagggcgaa gatgacttaa attttttaag ttttgacatg
    18961 gaaaatgcaa gtttagatga ggtagtagct gaagcagaga cgttgccgtt tttcggagat
    19021 caacggttag tattcgtaga gaatccttat tttttaacag gtgaaaaagt aaacaatgga
    19081 atcgaacaaa atactgattt attgacggct tatttgaaag aaccattaga atcgactgta
    19141 ttagtattct ttgcgccata tgaaaagttg gatgaacgga aaaaagtaac gaaacaattg
    19201 aaaaaaacag caattatcat caatgtccaa cagttgaatg aaaaagaagt acgtcaatat
    19261 ctgatgaata ccttagagaa ttcctcaatc aaaatggaac gaagtgcaat tgatttattc
    19321 ttgaggttga ccgacttaga tttatccaaa atgatgagag agttacagaa attggtcctt
    19381 tatggacaaa atcaacagca aatcacggta agagaagtag aagaattagt tcctaaaacg
    19441 ttagaacata atatttttga catgacccaa tatattttaa aagggaagac ggaacaagct
    19501 ttgcgtttat acgaagattt agttatgcaa ggggaagaaa caatcaaaat taatgcgatt
    19561 ttgctttctc aattacgttt atttttacag acaaaatttc ttgtaaagat tggttatcag
    19621 caggcaaata ttgctgaaac attgaaaatc catccatatc gtgtaaaact tgccatgcag
    19681 gaagtaaaaa aattcgatga acatttgctg gtacagttgt ttgatcaatt agttgagatg
    19741 gattatcaaa tcaaaacggg acaaatcgaa aaagaattaa gttttcaact attcgttttg
    19801 cgcacagggc agttgttaag aaatcgataa gaagaaagac gagggcaaag catgcgggaa
    19861 ggtcgtttgt ttttgtcctt tttttgacaa ataaaaaaat cggccgaagc cgattctttt
    19921 atttagcgat ttttttgctt aaacgagatt tgtcgcggtt agctttgttt ttgtggatta
    19981 gaccttttga ttcagccata tcaatagctt taacagcttc tttatataac gcatctacgt
    20041 tgtcagcacc tgaagctaca gcatcttcaa attttttgat tgcagtacgc atagcgcttg
    20101 tttgagatga atttttcaca ttagcgtttt cgcttgtacg aacacgtttg attgcagatt
    20161 caatgtttgg cattagtttc acctccgata acttaagttc ttacgcgtgt taccgcataa
    20221 ttcaacattc attattatac ctaaaggcag cgtgctttgc aatatgaaca tgacaagttt
    20281 ttttccttaa cagtctttta ttaggatttt ttttcagtaa aaacggatag tacaagctga
    20341 aaaaaatcaa aaagacgcta ttgtgggagg caatagcgtc aaaccaaact agatttttat
    20401 ttatctattt aaacaaagtt tgaatgggaa tgtttggtac taagttatta tataacaaag
    20461 agaaccgttt gcaaagtttt ttttgaaaag ggatacgatt ccctgttgtt ctttgttttt
    20521 ctattaagaa actgcagtta ttttataacc agtatccttt gatcagtaaa ggctattctg
    20581 gtgtaccgat tattttaatg tattcatcga tattttttat caacattttt tttatgacca
    20641 actggttccg acggttccat ttgccactta cttccagcac atatttattt aggggcaaac
    20701 gtaagatata ttttgccaaa tagcgatctt taagcaggcc attgatcaca cggtcctcaa
    20761 gctgcaagtt gatcccagtc agcatcattg gctgttcttg taaaacgtac gtatcaatta
    20821 aaagaccttc aaaagtttcc acaagcgtct tcctttcttt tcaaagtaac ctgaaaacag
    20881 gcactaattc ttccattttg atattcgttg aagtggatgc gatcattctt tcttttgtcc
    20941 actgtaatct agtataacaa aaaagagcag aagagccaaa aagaaaaaag agcatcgaat
    21001 tctataggaa gtctcattgg cacggcctaa attattacaa aacattgatt aaaaaaagcc
    21061 cctgcatcgc aggagcatcc cctatatcgt tttaataggt caatcaaaaa gcagtatcaa
    21121 acacattttg tatcaaatca ggaaataata gataagctaa gcccagaatc aaaagtaccg
    21181 ctagaagaaa ccagccgatt gttcctatga aatactttaa tttttcgaac attgtatcac
    21241 ctcgttgtca gtatatcacg gatcagtaaa ttgggggtgt taagaatctc ctaaaataga
    21301 caaaatttgt tctattttcc taaagcaaat acttgtaaga tacagtaagt gataccagaa
    21361 gcaatgaccg gtccggcggc gattcctctt aagaagacaa cacctaaaat cgtgccgaaa
    21421 acaagtgcaa cagtgatttg tggatcagaa gcaatcaatc ctacaccctt ggaagataag
    21481 acagccacta gcccaccgca aaaaacagct acccagccaa taggggattt aaaggcttct
    21541 aatagatcac gtagaccgat ttctcctgtt gcgataggga ttagaatagc cgctgtgatg
    21601 atcgtcaccc caatattgat tcctttgcct tgaagccaag ggaaaaagga acgggaggct
    21661 ggtatgagct tcataatcaa aacaaaagct gccgctatca tcagactttg atttttagct
    21721 aaaattgcta caagtaaaat aattcctaaa aaaagccaac tttccatgaa atatattcct
    21781 cactttcttc gaaacaatca taacatgttt ttagaaagtt acaaaagtag gaattcatcc
    21841 ttcaagacct attcataagc tgtttttttc ataaaataaa caaaatcata aaaaaacact
    21901 ttgcttattt gacagaagac agccgcgctt tgtatagtgg acaagactta catttttttg
    21961 aagaatcaga aagatcaggt aaaggtctta gtaaacgcaa gccattcaga ataaccaata
    22021 ttgtgcttcc ttcgtgtcct acaactccaa gaggtagatt taaaaattgc aggaagttag
    22081 aagcaatcaa caagagaata acaagaatcg aaaaaataat attttgtttg atgatccgcc
    22141 gcatttttaa agatagccga tgactgtaga caaatttatt taagtcgctt ttcattaaga
    22201 cgatgtctgc gatatccata gcggcatctg tcccttgccc catagcgaca cctaaagaag
    22261 cggctgctaa agcaggcgca tcattgactc catcaccaac catcgcattt acttggtaaa
    22321 gttcattctc ttttttgact agttgtgttt tttcttccgg agtacagctt gcatagtaat
    22381 gttcaatccc tacttgttca gcaatggcct ttgctgtgcc agaatggtcg ccggttatca
    22441 tacttgtatg gatgttttgg gatttaaagt aggaaattac ttgttgggta tttgcttttg
    22501 gaatatctag cagacctaaa acagcaatta actgctgatc tttagaaaga taaatcacgg
    22561 ttttgccttg attttccaaa cgttcgatca tttccgcaat ctctttgctg attatcatcg
    22621 tctcaggatc atatgcgtgc ttgccaactt tccattgcgc acctaaatag gtagtttgta
    22681 atccaaaacc agtaatttct tctattggta agtattggat ttcttcaggt attgtgcaat
    22741 cgaaatattg caaaatcgca tgagcaagtg gatgcgtcgt tttttgttcc atagcaacaa
    22801 gaagttgttg tgccaaatcc ttttcatcaa agaaaaagct gtcagttaca actggttttc
    22861 ctttagtgag cgttcctgtt ttatcaaagg caatcgcttt taattcagaa agcttttcta
    22921 aatggatacc gcctttgatt aaaatcccat tttttgcaga atttgaaaga gcagctagag
    22981 aagctggtgt agcagatgcg acaagcgcac aaggagaagc cacaactaat aataccattc
    23041 ctcgataaaa gctttcatcc caactccaac ctaggaaaaa gtgggggaga aggatcatta
    23101 gaggaacagc aagcaaaatc aattttacat aattattttc gattcgttcg ataaatgaag
    23161 ctgtttgagt tggcgtattc tgcgcttctt ctactaattg gataatctta gcaaagacag
    23221 tttcggaact cgtttttgtt actcgaatcg tgatgggatt tccttgattc agcgttcctg
    23281 catacatctc atcgcctaaa tatttttcta caggcacaga ttcaccgctt aatgcagact
    23341 catcgatcgt tgcctgtgtg ctttctaaaa agccatctat cggaacagct gctcctttag
    23401 cgacaaatac caagttatcc acctttagtt gagaaacatc tacttcttgc atttgtccat
    23461 tttcttttaa taattgggct ttttgtggtt gaagattcat caaagcagta atttcttttt
    23521 gacttttatt agttgtgtat tcctctaatg caccgcttaa acaaaagatg aatgtcaaca
    23581 ttgctccttc aaagtaatta ccgatcaaac aggcaccaat agcagctaaa gccatcaata
    23641 aatccacatt cagtgtccga tcattccaca attctttcaa gccttccgat gtttgtttat
    23701 atccaccgat gataatggca ctgatataaa aaagtggggt gatggtaaga gagaatcggt
    23761 cgaagataaa accgaagatc ataaataaaa ggcagccgat tgttgctgca aaagcttttt
    23821 tctgattagt catcgttatt agacctcctt gtcaaaacaa ggatagcata ataaaaatgt
    23881 aattgataat aataacagct aaatgagaac gataatggtt atcatttggt gattaagctt
    23941 gatgttgttt ttattattta taatgattat tattaaagaa aataaaaaac cagaacattt
    24001 ctcaaataag agaagtgttc tggttttttc tacattgcaa taaaccaata accaatcaaa
    24061 atgataccaa ggataatacg ataccagcca aaagcggtaa agtcgttttt cttcaaatag
    24121 cttagtaaga atttgatagc taagacggaa accacaaaag atacgaatgt tcctacaaga
    24181 agaacaacag tttcttccat tttgaatgaa ttcccttcag ctaaatattt gacgatcttc
    24241 aagccgcttg cgccaaacat gacaggaatc cctaagaaaa atgaaaactc tgtagcgaca
    24301 aaacgcgaag caccaatcaa gatagatcct aggatcgttg cgccagaacg ggatgttccg
    24361 ggaacaagtg ccaagacttg gaataaccca acaagaagag ctgcttggta cgtaaagtca
    24421 ttcagagaag tccaacgagg tgttttgttt ttgttgcgtt tttcgacaat aataaaggca
    24481 ataccgtaaa cgatcaaaac aatggcaact ggtaagaact tgtggaaatt tgcttctaac
    24541 caatcatcca aaggcaaacc aatgatgatg gctggtatgc aagcaacgat cactttaaac
    24601 caaagtgtcc acgtatcttt tttttctacc gttgatttac ttggagaaaa tgggtttaac
    24661 ttgtgaaaat aaagaacgac gacagccaag atcgccccta attggataac gacattgaac
    24721 atcgacataa attgtgaact ggcatccagt ttgatgaatt catctgctag gatcaaatga
    24781 ccagtactac tgatgggcag ccattccgtt attccttcaa taataccgag aatcactgct
    24841 ttgataatat ttgcaaaaaa cataaattcc ttccttccca attaagatac atcttatagt
    24901 ataccgttat tttttgagaa acccaatctg ttttttaata ttaagaaaaa cttgagaaat
    24961 aaagcagata agtacacgaa gagaaaaaag aagacaaagc cctcgttcag actttgcctt
    25021 ttatgattct ctggtaaaaa ttaaaatatc cccattatag aaacgagtcg cgactatgtg
    25081 ttttcccgtt atcgatataa gacgtatcat tgatgccgtg gatagaaaat cgaccgtttg
    25141 cataagtgac ctttgttacg ctgccattta aaagcccagc acgaacaggc tgtttaggat
    25201 cgatcagatt aagcaaaaag gcgatcgtca aaccatgaga tacgactaaa acatttccac
    25261 caccattttt ttcgcagtga tgggcgatat cttcaaatcc tgtccataca cggtctcgca
    25321 atgtttcata agtttccgcc cacccagcgg tatctaagtt gtatacagca ttagcaattt
    25381 gttcaaaaga aacttctgtg gtaaacattt catcatatgt tttaaaattc aatacacgag
    25441 ggatcacacc ccacatttcc atgtcatatc caccttcaag agacccgaaa caccattctc
    25501 taatcctttt ttcaataaaa taaggaattt cttttccctt agaatgttct cctagaataa
    25561 tacgggcagt ttcgattgca cgaccactgt cactagaata agcaaatgaa aagtcgacat
    25621 tttttaaccc gcgacctaaa taatgaatgc cttcttgtcc ttgctttgtg aggggtgtat
    25681 cacaccagcc ttgtactcgt tcaattgtat tgaacatcgt ttttccgtgt cgtacgatat
    25741 aaagtgtagt ttctgtcatt ttattctcct cctaagtcgt tttaacgatt gaaaaaagga
    25801 tttgtccttt tttcctgttc aatcgtcgtt gcatcgccat gtcctggata gactgcaaat
    25861 tcatcaggta atacaaacag ctgggtccga atactatgaa gtaattgttc taaattccct
    25921 gtatacagat cggttctacc gatacttcct ctaaacaggg cgtcgccaga aacgacaaaa
    25981 tcatcaaaaa taaagctgac gcttcctata gaatgccctg gggtagggac gacgcgaaaa
    26041 gacatgtttc ctaaagtata agttttcatt tcaaattcat attctgcagg cgagacaata
    26101 acatcagcaa tatcatcatg tctaccgagt ccagaaagat tcaaaatcgg atcacctagc
    26161 catttttgct ctagtgggct gacataaact gggatttgat aatacgcgcg taaaggttcc
    26221 actgcaccga tatgatcgta gtgagtatgg gtaagcaaaa tcgctaccgg ctgttggttt
    26281 gtttttttga tttcttgttt gattcgttcc gcatcttctc cagggtcaat gatcaaaagt
    26341 gcttcttcgt tgtagaccaa ataacagttt tcttcaatca ttcctgtttt taatctttcg
    26401 atatgcatgt gcattcctcc ttgatagcca aaacttcttt catccattag tataacgcat
    26461 tcattgctag gaaacaaaaa caggtactta tttctcttta cttatctgaa ttatcagact
    26521 atatgaaaag tatttggata ttctaaagag aaggaaagta agttttcata gcattttaat
    26581 atgtccttgt tacattagat tcatccaaaa atccaaattc tatatcctat atccctgcct
    26641 aatcagcagg gtgttttttt atgtttggaa agagagctct ttttgctaaa ctaggttttt
    26701 tcaggtaatc ttagagagaa agaggtggtg gaaatgatca aacagtcaaa aatatctgtg
    26761 cggcacttag tagaatttat tttgcgacgt ggaagtatcg acaatcgtaa aaaaagtaac
    26821 catactgcat tagaaggagc gagaatccac cgcaagctcc aaaaagatgc gggagaaaac
    26881 tatgaaaaag aagtcttttt aaaaacaaca gttcaattag atgaatatta cctgatcgtt
    26941 gaaggccgtg cagacggtat tttcaaaaga gacggtattt attatataga tgaaatcaaa
    27001 acctccgaac cacgatttga agatttagaa ccagaacaag tggaactttt ctttcatcaa
    27061 gcaagggtgt atgcctatat ctatagtcaa gaacatgatt tacaagaaat aaatctgcaa
    27121 ttgacttact tccagacggc agaagaagtg atcacgagaa aggttgaaca tcagacaaga
    27181 gagcagttag aaactttttt taaaaagctg actgaagatt ataaagaatg gcttgttttt
    27241 caagaaaact ggcgcactgt acgcaatgcc tctttgatgg ctttgaaatt cccccatgat
    27301 gagtatagga aaggtcagcg tgaactagcg gtagctgctt ataaaacgat ccgtacgaaa
    27361 cagaaattgt ttgtagaagc acctaccgga acaggaaaaa caatctctac gttattcccc
    27421 gctttgaaag ctgtagggga agaagaggga gaaaagatct tttatctaac ggctaaaaca
    27481 ataactagac aagtagctga agatgctatg acagcattaa aagatacagg agctgaagta
    27541 aaaagtgtca ctttgacggc gaaagacaag atctgctttt tagatgagac gacctgtaat
    27601 ccagatcagt gcccatatgc caatggttat tacaatcgga ttaatgaagg tttatgggat
    27661 cttttgaatc atgagaatca gatcactcgt gaagtcatcg aaacttatgc aagaaagcat
    27721 acactttgtc ctttcgaact atcattagat gtcagtatct ggtgtgacgt aatcattggg
    27781 gattacaatt atttatttga tccaactgtt tatttaagac gtttttttga agatgaaaaa
    27841 aacgaggact atctgttttt gattgacgaa gcacataatt tggtgaatcg ttcccgagag
    27901 atgtattcgg cagaactatc ttatgaaaaa acgaaacgaa gtaaggaagc tataccaaag
    27961 gaattcaaaa aacttcatcg ccgtttcaac aaactattaa aagaatttga ttcgatccga
    28021 gaaatagcaa aagaagatca ttgggattat catcatcaaa aagcaccggc tgaatcttta
    28081 gtaaaggcag gttatcaatt aagcgaaaaa attaaagaat ggctggcaga atttcctgag
    28141 cacccatcac aagaacaatt gcttccttat tattttgatt tgcttcattt tttgaaggtc
    28201 agtgaatttt atgatgatca ctacgaaaca acagtcgaaa aaacgtatcg cgatctgata
    28261 gtaaaagagt tttgtattga tccaagcttg tttcttgagc agtcgttgga taaaggaaaa
    28321 agcagtattc ttttttctgc tagtttttca ccactctctt attatcagga aacactgggg
    28381 ggacaaaaaa gtctggctta caaactgccg agtcctttcc cagaaggaaa ccagcaagtt
    28441 ttcatcgcaa attacctaga gacgacttat cgaaaaaggg aacacagtct ggcaaaatta
    28501 gtagagacga ttcatgcttt tgctgatgga aaggtcggga attatttcgt tttctttcct
    28561 tcttatcaat atttagatct tgcggtggaa gcattcagac agcaatatcc cgacagcaat
    28621 gtgctaatcc aagaaacgga catgaatgag gaagaacgcg aacgattttt aacaaaattt
    28681 caaacaaatc ccgctgaaac attgattgga ttttgcgtac ttggcgggat tttttcagaa
    28741 ggaatcgatt tgagagggga ccgattgatc ggcagtatga tcgtaggtgt aggtttgccg
    28801 cagatgaatc atgagcagga actgatcaaa tcatattatg atgagaagga acaccttgga
    28861 tttgcttacg cttatcagct tcctggaatg aacaaagtct tgcaagctgg tggtcgagtg
    28921 attcgtggca tggcggatca aggaatcgtt gtattggcag atcaacgatt ttctagtttt
    28981 tcttatcgac gtttattccc acaacattgg caaacagcaa gagaagtacg aagtgttggg
    29041 gaattggaag aaggaataca gcgtttttgg ttatcaaaag aagcagtaaa tcaaaaaaac
    29101 gaggaatgac agacgtcagc ctcgtttttt gattaacgat agttagtgaa ttgcaactcg
    29161 attggtaagt caagtttacg taataaagca atcacagctt gtagatcatc acggttctta
    29221 cctgtcactc taatctgatc ttcttggatt tgtgctttta ctttcagttt ttcatttttg
    29281 atagctgtag tgattttctt cgcgttttca cgatcgattc cgttgaccaa atcggcagtt
    29341 tgtcgagctt tgccacctag agcgtgttct gattcggaaa aatggatatt tttgattggc
    29401 acatttcttt tgatcagctt accaaataat acatctttga tctgttcgat tttgaaatca
    29461 tcatcgctca atacaactag attgctgttc tctaatttga tttctactgt agaatccttg
    29521 aagtcaaagc gattggacaa ttcttttgtt gtttgctgaa tcgcattttt tacttcttct
    29581 gtattgactt ctgatacaat gtcgaagcta gcatcttttg ccataggaac cctcctgata
    29641 tacatataaa tatttaccat acatctatct tatcatagga ttagggcaga ttcttacctg
    29701 tttgctaaaa ttcttctcat ttgagttcga agtattttat tttaatagat aaactgttat
    29761 tcttacattt ggaataccaa agtaggggag aggtgcttgt gagtaaaatt atgactgcgt
    29821 atcataaaaa tgaaagatta aagaaaatag tggttatttt gataaccgga ttgaccgctg
    29881 cggtcgcttt aaattatttt ttgattccag ccaatgtctt ttctgcaggg atgaatggga
    29941 tcgctcaaat catttcctcg cttttatatg aatggtttca tatcaagata gacacaggaa
    30001 catttatttt tcttttgaat atccctgtgt ttgtattagg gtttctcaaa gtaggaaaac
    30061 gagcaacgat ccttagtttt gtgaatgttg tatgtgtatc ggtgatgacg atgctgcttc
    30121 cagtcggaca gatcactgat aatattttga tgaatgccct agtaggcggt gttttattag
    30181 gtcttggcgt aggattatct ttaaaaatgg gctttacaac tggtgggatg gatatcatct
    30241 ctcttgtact ttcacaaaca actggaaaaa cagtcggaaa ctacatgctg attctaaatg
    30301 gtatcattgt agtcatcgca ggcttcttct ttaactggga aagtgccttg tatacgatta
    30361 tttccattta tgcaatgact caagtaattg atgccatcca cacgagtcat caaaaagtaa
    30421 cagcaatgat cgttaccgtc aagccagaag aggtaacaga agaactagca aaacggatgg
    30481 tacgtggaat gacattactg ccgtctgtcg gtggctattc aaaaaaacaa gggaacatga
    30541 tcatgatggt catcacccgc tacgaaatgt atgatcttga tcagatcgtt catgaaatcg
    30601 acgacgatgc atttatcaat attttaccaa ctcattcagt atttggccgg tttgcaaatg
    30661 aaaacgaaca aaaaatgtat cgaacaactg gcgtattgcc agaaataaaa aatcgttcac
    30721 aaaaaaaatg aggaatcagg tttattttag aataaattta atctattaca tctaataaga
    30781 acatttttat aaatttaaac gagaatctta cttctaaatt ctcatttaca agcagctaaa
    30841 aaaagagtat gataaataaa aatcgtgtta aggagtgtcg tacgatgagc gaagcaaacc
    30901 aagaacggtc tggacaagaa atagaactaa tcaaagaacg tattcttgct gccttggaaa
    30961 tggtgattga tcctgaatta ggaatcgaca tcgtcaattt aggcttgatt tatgatatag
    31021 aattcaatcc tgaaaatgga gaaacagtca ttaagatgac tctaacaact atgggctgtc
    31081 cattagcaga tattttaaca gaatctatcc atgacgcatt aaaagaagtg ccagaagtaa
    31141 cgaaagcaga agtcaaacta gtctggtatc cagcatggac gacagataag atgagccgtt
    31201 atgcacggat tgcgttgggg atacgataga aatcttggct gactagctat gagaagcaaa
    31261 taggaaaaac aaaaaagcct tttatccttt ctagaagaaa agagataaaa ggtttctttg
    31321 tttataaaat tttgtctgct atattataag ttaattaaat aaatgtgttc tattgataaa
    31381 ggacattcaa atccctttcc ttttggaatc cttctttttt acatcagttt gattttcgta
    31441 tagtattctt tctcatcttc acgataaatc gcagccccat ttttttgttg tgctttaaga
    31501 ctgccaagat tttttttatt tacagacaaa agtgcctcat caatgccgat tttttttgcc
    31561 tcttgtagta ctaatgctaa tccttgtgtg gcatatcctt ttttacgata attaggggag
    31621 atgccgtaac caatatggcc agcgccgttt cttaatgttt cgttcagttt atggcgcaaa
    31681 ttaaaaattc ctacatactc atgttcatca ctttctaaaa taaagacggt tgcgggaacg
    31741 taactctcag gaagatcgat tcctaaagac gttttttcgc atttttttac ataatctaaa
    31801 aattcagcaa atgtatagcc ataagcattg ttgataaatc cactctcatt tggtccaaag
    31861 ctagtttgta gctgataagc tttctttaaa tctgcttccc atagtttgat cagtttcatc
    31921 gtattcacct ctttaagtaa ccttattcat ttgttttcta ctatagcact attgttgtaa
    31981 atagccatgc ctatttttat ttattgtgtc atatcgtatt aagaatcatc gaacaataca
    32041 aatatgaatt acaataaaaa aattatttga agttcgttca ttcgttactt atgatctcta
    32101 gaagaaagaa aacgtgaatt acttcagcgt ctagaattcc agaaggatag taatcaacag
    32161 aagaaataat caatatccaa atgaaagaag atagctgaat cgagaaaaag aggaaaaaag
    32221 aaatgaagaa aaaaataaaa tagttactaa tcccagagtc gttcgtttaa cattgaaatc
    32281 gatcatatgg ataaaacaga ttttttcacc aaccctcaat agatgatgga gttgctcgga
    32341 tgaattattt gtgtagatgg cataagggag ggcgtacaga aatgaaaaag aacaaaaata
    32401 tgttcttgac aaaaaacaca tgtaatccta aactaaaaga tgtgatgcgg ctatggcgga
    32461 attggcagac gcgctagctt caggcgctag tgagggtgac ctcgtggaag ttcgagtctt
    32521 cttagccgca taatttgttt ttttataaag agaaggtaca cctggagcga tgagaaagaa
    32581 aataacatat tatctaaaag aatataggaa aaattttaaa caacggaacc agattcaaat
    32641 aaatcaaaaa aaatttgtgt gaaggtggga cagtttaaaa cctaatagat tgattcaaat
    32701 agtagattta tagattctga tacaagaaat actggcaaac gatagttaag gaataaagac
    32761 taaacttaaa ctcaaaaaga ggtcatgcga aagaataaat cgcatgacct cttactatat
    32821 tttgaatgtg tttaaacgtt caaataatga atcttagtac caaccgtttg cttcccagaa
    32881 tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg ctactctttc
    32941 ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt aacggccgat
    33001 gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga tccattcttt
    33061 tgcagagctt gtacttgctg gagtagcagc agtttctgtt acagcaggag caggttgtgt
    33121 ttcagcaaca ggcgctgctt gtgtttccgt ttgaaccgtt tcttgtacaa caggttgttc
    33181 agcttgaaca ggttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    33241 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagta
//
LOCUS       DAIGQM010000028        32506 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.028, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000028 DAIGQM010000000
VERSION     DAIGQM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.028"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            106..771
                     /locus_tag="NOA48_001318"
                     /pseudo
     CDS             106..771
                     /locus_tag="NOA48_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            918..1283
                     /locus_tag="NOA48_001319"
     CDS             918..1283
                     /locus_tag="NOA48_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCI0789589.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(1431..2639)
                     /locus_tag="NOA48_001320"
     CDS             complement(1431..2639)
                     /locus_tag="NOA48_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0789590.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2658..2936)
                     /locus_tag="NOA48_001321"
     CDS             complement(2658..2936)
                     /locus_tag="NOA48_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789591.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            3090..3785
                     /locus_tag="NOA48_001322"
     CDS             3090..3785
                     /locus_tag="NOA48_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0789592.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(4227..5024)
                     /locus_tag="NOA48_001323"
     CDS             complement(4227..5024)
                     /locus_tag="NOA48_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCI0789593.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(5021..6205)
                     /locus_tag="NOA48_001324"
     CDS             complement(5021..6205)
                     /locus_tag="NOA48_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0789594.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(6230..7477)
                     /locus_tag="NOA48_001325"
     CDS             complement(6230..7477)
                     /locus_tag="NOA48_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0789595.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            7692..9437
                     /gene="dnaX"
                     /locus_tag="NOA48_001326"
     CDS             7692..9437
                     /gene="dnaX"
                     /locus_tag="NOA48_001326"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCI0789596.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            9457..9771
                     /locus_tag="NOA48_001327"
     CDS             9457..9771
                     /locus_tag="NOA48_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCI0789597.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            9796..10392
                     /gene="recR"
                     /locus_tag="NOA48_001328"
     CDS             9796..10392
                     /gene="recR"
                     /locus_tag="NOA48_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCI0789598.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            10456..11100
                     /locus_tag="NOA48_001329"
     CDS             10456..11100
                     /locus_tag="NOA48_001329"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCI0789599.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            11115..11444
                     /locus_tag="NOA48_001330"
     CDS             11115..11444
                     /locus_tag="NOA48_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCI0789600.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            11458..12396
                     /gene="holB"
                     /locus_tag="NOA48_001331"
     CDS             11458..12396
                     /gene="holB"
                     /locus_tag="NOA48_001331"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCI0789601.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            12432..13256
                     /locus_tag="NOA48_001332"
     CDS             12432..13256
                     /locus_tag="NOA48_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCI0789602.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            13249..13596
                     /locus_tag="NOA48_001333"
     CDS             13249..13596
                     /locus_tag="NOA48_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCI0789603.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            13665..14537
                     /gene="rsmI"
                     /locus_tag="NOA48_001334"
     CDS             13665..14537
                     /gene="rsmI"
                     /locus_tag="NOA48_001334"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCI0789604.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            14646..15767
                     /gene="dinB"
                     /locus_tag="NOA48_001335"
     CDS             14646..15767
                     /gene="dinB"
                     /locus_tag="NOA48_001335"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCI0789605.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(15821..16423)
                     /gene="nrdG"
                     /locus_tag="NOA48_001336"
     CDS             complement(15821..16423)
                     /gene="nrdG"
                     /locus_tag="NOA48_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCI0789606.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(16738..18927)
                     /gene="nrdD"
                     /locus_tag="NOA48_001337"
     CDS             complement(16738..18927)
                     /gene="nrdD"
                     /locus_tag="NOA48_001337"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCI0789607.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            19226..20020
                     /locus_tag="NOA48_001338"
     CDS             19226..20020
                     /locus_tag="NOA48_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789608.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            20010..22052
                     /locus_tag="NOA48_001339"
     CDS             20010..22052
                     /locus_tag="NOA48_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789609.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            22333..22482
                     /locus_tag="NOA48_001340"
     CDS             22333..22482
                     /locus_tag="NOA48_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCI0789610.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            22493..24007
                     /gene="dltA"
                     /locus_tag="NOA48_001341"
     CDS             22493..24007
                     /gene="dltA"
                     /locus_tag="NOA48_001341"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCI0789611.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            24004..25209
                     /gene="dltB"
                     /locus_tag="NOA48_001342"
     CDS             24004..25209
                     /gene="dltB"
                     /locus_tag="NOA48_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCI0789612.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            25254..25487
                     /gene="dltC"
                     /locus_tag="NOA48_001343"
     CDS             25254..25487
                     /gene="dltC"
                     /locus_tag="NOA48_001343"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCI0789613.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            25490..26758
                     /gene="dltD"
                     /locus_tag="NOA48_001344"
     CDS             25490..26758
                     /gene="dltD"
                     /locus_tag="NOA48_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCI0789614.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            26899..27981
                     /locus_tag="NOA48_001345"
     CDS             26899..27981
                     /locus_tag="NOA48_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCI0789615.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            27981..28784
                     /locus_tag="NOA48_001346"
     CDS             27981..28784
                     /locus_tag="NOA48_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0789616.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            28854..29594
                     /locus_tag="NOA48_001347"
     CDS             28854..29594
                     /locus_tag="NOA48_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0789617.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            29605..30609
                     /locus_tag="NOA48_001348"
     CDS             29605..30609
                     /locus_tag="NOA48_001348"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCI0789618.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(30654..32498)
                     /locus_tag="NOA48_001349"
     CDS             complement(30654..32498)
                     /locus_tag="NOA48_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789619.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        10338 a         5726 c         6640 g         9802 t
ORIGIN      
        1 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
       61 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaacgtgac
      121 cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc catgcttatt
      181 gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga agaagaaaca
      241 gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat ggtcttattc
      301 ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt tgatggtttg
      361 cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac aacggcaaaa
      421 gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg ttcaaaagcc
      481 tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg cgggctagat
      541 ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa agcttttaga
      601 aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca taaattcatg
      661 catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga actgacaaaa
      721 gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata aattattacg
      781 tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct cgcttctctc
      841 agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt tttatccagg
      901 agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca atcatgatct
      961 gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg gattcaacga
     1021 ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg atcttacgta
     1081 aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt atcttgtggc
     1141 tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg attcctgctc
     1201 tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa ggcatcgtac
     1261 cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat aaatgaaagc
     1321 tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac tcaaaaaacc
     1381 gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga tcaaatttca
     1441 tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg gccattaaca
     1501 agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa tcctctaaat
     1561 gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc taggtctaaa
     1621 ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat ttttaaacaa
     1681 acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc tccagagata
     1741 agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt taagaataaa
     1801 tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc agtcaatgga
     1861 cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc agcaactaag
     1921 tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga aagacccatc
     1981 aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt gatattccat
     2041 gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg aaagacaagg
     2101 caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa acgaaaatca
     2161 gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa actagtactt
     2221 aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc agtaacgata
     2281 gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg aactaaatac
     2341 aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata gaagatcgcg
     2401 ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat gaataagcgt
     2461 gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct caagctggcg
     2521 tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata aatcaggtag
     2581 acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt cttttccatg
     2641 tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg aacttctaca
     2701 tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc tcttgtagac
     2761 ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac tgctttgatc
     2821 aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt catatcaaat
     2881 cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta attcatgttt
     2941 tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa aaaggaaaaa
     3001 aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag taaaatacct
     3061 ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt ttggatgggg
     3121 gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat tttccgatta
     3181 tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc catacgtata
     3241 tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga gaatttaacc
     3301 ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat tcacaattca
     3361 tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat cgaatcaatc
     3421 gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat gtaaaagagt
     3481 attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta ttaaacggaa
     3541 agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt gtgcggacag
     3601 aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa ttttgtggca
     3661 tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat ggtattatca
     3721 ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac aatattatct
     3781 tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg
     3841 gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc agctgattga
     3901 acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa ggaacaattt
     3961 caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga gttggtagga
     4021 gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat aagaagagcc
     4081 aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta gatgtaagct
     4141 tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc acagcccttt
     4201 ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc aaaagtcccg
     4261 ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg gcttttgggg
     4321 attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt taatttgata
     4381 ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata acgcgaaaca
     4441 gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat gatgatttct
     4501 actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac acgataatgt
     4561 cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc ttttgcagca
     4621 ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga atcgattctg
     4681 ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc acgctgtccc
     4741 atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct taagtaatta
     4801 tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa gactcgtcct
     4861 ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg atctgttgtg
     4921 aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac cggccagcca
     4981 acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag taacctccga
     5041 tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc aattttttct
     5101 ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg tagtagtaga
     5161 cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt aatacgtaat
     5221 tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt gtatatccat
     5281 ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga atctgtgatt
     5341 tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa tactggcttt
     5401 taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc ttttgttgcg
     5461 tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct gctcttgaaa
     5521 cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg cggataactg
     5581 taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa gggaaataca
     5641 cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca aaccattttt
     5701 tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca aaaggaagta
     5761 ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga ttatggcagt
     5821 agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca cagttgggac
     5881 aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta tctgaaaaac
     5941 cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc tgttcttggg
     6001 ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg ccagccatac
     6061 gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag atattcaggc
     6121 agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg ccgcaattag
     6181 gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat taattaacgg
     6241 ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg ttggaaagat
     6301 ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg ttttctacag
     6361 gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg caaactggac
     6421 atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct gcttgttgtt
     6481 tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt gcattcattc
     6541 ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg gctgcttcca
     6601 taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca cctagcatcg
     6661 ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa atgctggcta
     6721 cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc aatgcagtat
     6781 ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt tgaccatctg
     6841 cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa tactgctcat
     6901 tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta taaaataaaa
     6961 tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat tctgcgttat
     7021 agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc tttatttctt
     7081 ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat ttgaatcggt
     7141 caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga gctgcgtcat
     7201 ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca ccatcgacca
     7261 aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa acatcttctg
     7321 ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct tttgtcatga
     7381 ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct gccagaccgc
     7441 cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc tctgattcag
     7501 ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa acttctcgga
     7561 ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa aagccgagaa
     7621 ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt ttttaaaaaa
     7681 gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag cgtttcgaag
     7741 acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt tcccacaaaa
     7801 cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt gcagcaaaga
     7861 ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc aacgaatgcg
     7921 aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc gatgctgcca
     7981 gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat gcgcctacaa
     8041 aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca ggagctttca
     8101 atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc ttagcaacga
     8161 ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt gattttaaac
     8221 ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa tcgactatca
     8281 gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg atgcgggatg
     8341 cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact ttagatgatg
     8401 ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg agtgcttgcg
     8461 tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca gccggcaaag
     8521 aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg atgtatcagc
     8581 aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt acagaattgg
     8641 cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc gatactcaaa
     8701 atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca gtcaaacttg
     8761 cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat gatcagatag
     8821 taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa ctacgcagta
     8881 atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat aaaaaacaga
     8941 caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa gcgacaagac
     9001 agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta tctgtcactc
     9061 agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga ctagtgattg
     9121 cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg cagctttcgg
     9181 tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt tatattacaa
     9241 gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa gagggaacag
     9301 aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct caagaacaag
     9361 aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc gaagctgtta
     9421 cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat gggcaatatg
     9481 caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc acaagagctg
     9541 ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc ggtttttaca
     9601 ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc tgatgatatc
     9661 gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca aattgatgtg
     9721 gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta gttttaaact
     9781 gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga cagctacatg
     9841 aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac gatcgatatg
     9901 aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg cgatttgcat
     9961 ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg tagaaatcct
    10021 tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat ggcaatggaa
    10081 aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc accgatggaa
    10141 gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca tgatgcagat
    10201 gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac agctatgtat
    10261 ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca tggtctgtct
    10321 gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt cgaaggaaga
    10381 cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag cagcacaaga
    10441 gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga tggtgcagga
    10501 aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa aacagaaatc
    10561 attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc agtgatcctt
    10621 gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc agcagcaaga
    10681 agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat cgttttatgc
    10741 gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat cggcgttacc
    10801 gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt taccctttat
    10861 cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca aaatcaaatc
    10921 gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc ttacttaaag
    10981 ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag ctttgaagaa
    11041 gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt tgaaaactag
    11101 gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac agcaaccgtt
    11161 tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg acaggcggct
    11221 tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt gtagaagaag
    11281 cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct acacctgtta
    11341 cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa gtaggcggtg
    11401 ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag ctgagctatg
    11461 aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct tcaacggagt
    11521 tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg aacaggaaaa
    11581 catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa agacaatctg
    11641 ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc agatgttttg
    11701 gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt gcagacggaa
    11761 ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga agctgaaaaa
    11821 atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc tggagatttt
    11881 ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca atctcgttgt
    11941 caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt gcaagaagag
    12001 cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt aggaaaagca
    12061 gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta tcaatggttc
    12121 gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa attggtaaaa
    12181 tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt ttattatcag
    12241 gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca gataaaccag
    12301 ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag ttttcaggct
    12361 gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga tgatgatcaa
    12421 ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt catatctatt
    12481 attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc gaatctcagc
    12541 aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc aatgaccttc
    12601 ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa aaagacaaaa
    12661 aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg cagttgcgtg
    12721 agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa ttgatttttt
    12781 ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg gccgctgtat
    12841 ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag ataataggcg
    12901 gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat ttcgtgcctg
    12961 tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa atttccggtt
    13021 tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag acagcgaaaa
    13081 aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg aaagtcgtag
    13141 ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa aatcctgtcg
    13201 aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat ggataagaga
    13261 tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt aacagaactt
    13321 gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt ggagatggaa
    13381 aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc tccagctgaa
    13441 aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta tgaagaagga
    13501 ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc ttgtgcgttt
    13561 tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg agactggagc
    13621 ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat aatcaaaaaa
    13681 gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca attggaaatt
    13741 tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt atcgcaagtg
    13801 aggatacgcg taatacacaa aagttattga atcattttga aatccataca ccccaaaaaa
    13861 gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg ttaaaagaag
    13921 gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat cctggacatg
    13981 agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca ggacctacag
    14041 ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta ttttatggct
    14101 tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa gaacagacag
    14161 ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg aatttcttag
    14221 aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc catgaagaat
    14281 accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca gtaaagggtg
    14341 aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa gttgatgaag
    14401 agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa aaaccaaatg
    14461 ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc taccgtcagt
    14521 accatgaatt agactgagat agtataagtt gtctataatg aaagactaat gaggaaatca
    14581 gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat gaataagagg
    14641 tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa atcattcata
    14701 ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag tttcgcggac
    14761 atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta gtgactacag
    14821 caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa aaagcgtatg
    14881 agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc gatatttcca
    14941 aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt agtatcgatg
    15001 aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc aaaatcgccc
    15061 gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg ggagtaagtt
    15121 acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga atcacggtag
    15181 ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa tttcatgggg
    15241 tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga aaagacctat
    15301 atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat tctctttatc
    15361 gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga aaatctgtgg
    15421 gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg actcagttgc
    15481 gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat gggaaaacag
    15541 tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg acattgccag
    15601 aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg gaggaaatct
    15661 tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg gacccgatga
    15721 cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa cagctttgag
    15781 agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag tcttgctttt
    15841 tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca acttgattgg
    15901 attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga aattgtagtt
    15961 ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt tgcgaaagga
    16021 gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct gtccatgacc
    16081 agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc agacaaacat
    16141 ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa tcgttgcgca
    16201 agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat cggaaatttt
    16261 gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg taaagactgt
    16321 tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata tagttttggc
    16381 tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa cttctttcat
    16441 ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata aataagaaca
    16501 aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag ggcgttcaaa
    16561 gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc ttattctgaa
    16621 taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga aaaatatgag
    16681 gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt cacaacctca
    16741 tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca tcggacgagc
    16801 ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt ttggatcatg
    16861 atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac cttcgaaacc
    16921 acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt tgtcatatgc
    16981 aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt attcacagta
    17041 gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca atttttcaaa
    17101 tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt ctttatctgt
    17161 gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt cagttagact
    17221 ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc atgcatctgc
    17281 attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg ggtttgtttc
    17341 ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc ctaacgatac
    17401 agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa gacgtttccc
    17461 gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt tacaacgttc
    17521 tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta actgccagaa
    17581 tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg taacaacacc
    17641 taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc cttgcaagaa
    17701 tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt tatcgtaatt
    17761 cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt tgatgtcgta
    17821 attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca gtttagggaa
    17881 gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa ttgctttttg
    17941 aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga aaggagtttg
    18001 tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag catcgaagat
    18061 atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat cgatccattc
    18121 ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa gcaattcatc
    18181 tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa taatctgtga
    18241 gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat tgccgatttt
    18301 gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca tcggtgtata
    18361 aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat ttgctatatg
    18421 tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca gatctcgctg
    18481 tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt ggtccttgtt
    18541 gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa aatctcgttt
    18601 ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta gtaatatatg
    18661 ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc ttttgatttc
    18721 ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg ataatgagcc
    18781 gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat cgaaatcaac
    18841 atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct gagtaacgac
    18901 agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg ttcttgtcta
    18961 tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt attcaatgtg
    19021 ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa aaaggtgaaa
    19081 acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa ataattgaat
    19141 aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat tattcgtaga
    19201 tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag aattggaaaa
    19261 gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc ccgtcaaagc
    19321 cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta tgggcccaag
    19381 tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc ctacgatggg
    19441 cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc tcagtgactt
    19501 tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata ccctaaatgc
    19561 aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg aaatggaaaa
    19621 gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac ggtatcccga
    19681 tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg ttgttcagcc
    19741 acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg ctacagaatt
    19801 gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt tagtcaccca
    19861 tgatccatat acagcaagct actgcgatag aattttattt attaaagatg gtgtgatttt
    19921 ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa tagacatgca
    19981 ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt aaaagttttt
    20041 ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc gtaatgatct
    20101 attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca agtcaagata
    20161 cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt ttgctttttt
    20221 tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata ggcatctatc
    20281 agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa atcatgataa
    20341 ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc aaactctttt
    20401 caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt atctccattc
    20461 catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta tctgtatatt
    20521 caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa gaacaagcag
    20581 atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc gggttactac
    20641 ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca tggatgatca
    20701 gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt ttcgtttgtg
    20761 tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc atattgagta
    20821 aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg caagttcatt
    20881 tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt tctttaatga
    20941 caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa gtttcctccc
    21001 cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt ctagcagagg
    21061 aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg agtatctata
    21121 gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa acacaatatc
    21181 aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca cctggtcata
    21241 ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat ggatctagta
    21301 ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt gtattaggtg
    21361 acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt tttgaaaaag
    21421 caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat aatgaaaaaa
    21481 tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt tattattctt
    21541 atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt ccggatgacc
    21601 aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct tccagctatt
    21661 cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca ctatttgtcg
    21721 ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta gcagaagcag
    21781 aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa agaaggatca
    21841 gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata ttagggatca
    21901 ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc gattactggt
    21961 tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat gtcattacga
    22021 gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag ataataaata
    22081 gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat ttttgtcaca
    22141 acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa aagcagtgat
    22201 ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa acggtttctg
    22261 taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga ggttatatga
    22321 ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg gggaaaattc
    22381 atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct gtatcactat
    22441 aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga gtatggaaat
    22501 caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc gagttgctta
    22561 tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg cacttgctta
    22621 ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca atttggagtt
    22681 tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt tgccgattga
    22741 agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac catctatggt
    22801 catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa caaaaaaaga
    22861 atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg taaaaggtac
    22921 agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag gcgtacaaat
    22981 cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg ggatcaagcc
    23041 tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat tttctattta
    23101 tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg ttcaagactt
    23161 tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt ctactccatc
    23221 atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc cggaattgga
    23281 catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc tacttgatcg
    23341 attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg tagctatttc
    23401 aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga ttggctacgt
    23461 aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa aaggagaaac
    23521 gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca atcccgaaaa
    23581 gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag gggatgcagg
    23641 tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc aggtcaaatt
    23701 acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag acaaccgaat
    23761 caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc tggttgcttt
    23821 tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat ctatcaaaga
    23881 acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt atgtcgatct
    23941 gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg aggtgaatcc
    24001 tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt tcttttagcc
    24061 attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt accagtttat
    24121 caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta ttggcaacag
    24181 ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg ctattttgtt
    24241 tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt agcgataatt
    24301 ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc gttacttggt
    24361 tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga aataagagat
    24421 ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt ctttccaaca
    24481 atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct ccatccgcct
    24541 gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt tgtcggtttt
    24601 ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt agtgggacgc
    24661 attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta cgtgtacagt
    24721 atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac aagctacatg
    24781 atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa tatcaaagaa
    24841 ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt atatatgcga
    24901 ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat gtcaaatatc
    24961 ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg gtactacatc
    25021 gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat ccgatttaag
    25081 aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc cgtatttttg
    25141 acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga taaacttttt
    25201 tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg aaaatggaag
    25261 aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga aaaaatcgtg
    25321 atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa ttattagtcg
    25381 agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga gaggattgga
    25441 gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta tgaaaaagaa
    25501 actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg tgttttttac
    25561 ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct cttcttccat
    25621 gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg aaaaacaata
    25681 tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc cgtctgttct
    25741 ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg ggacacaatc
    25801 gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca agaaagtcgt
    25861 ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt actttaatac
    25921 gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag taacgcctgc
    25981 tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga atgatacgtt
    26041 gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat ctttgaatca
    26101 gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca atattgggtt
    26161 gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac aataccaaga
    26221 aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga ataatccatt
    26281 cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag agctcaaaca
    26341 gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc agctggtctt
    26401 ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg ttaacgagaa
    26461 atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca aaaagatcaa
    26521 atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc aagcgggtac
    26581 caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg ctgcagatca
    26641 acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc atcttgacga
    26701 tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat taaaataaag
    26761 aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga ataaaagata
    26821 aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca atatgaatat
    26881 agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga tttaacttct
    26941 gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga atatgccaaa
    27001 ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa acatggtgct
    27061 ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt tatggtaaca
    27121 aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg ggggcaagtc
    27181 atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca cggtgtgatt
    27241 ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta tgaaataaag
    27301 gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg gggcatacgt
    27361 cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag taaatattta
    27421 ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt attagagaat
    27481 ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca agaagaagta
    27541 ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc ttttgcttta
    27601 gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga ttcgatttta
    27661 ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa aaaattattg
    27721 aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac agtgatttct
    27781 ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc gtctgtagcc
    27841 attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga agatgattat
    27901 ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga aacagttgaa
    27961 aaaattcgga gttatgaata atgaataata gaatacctat ttctgaatat cggaaaaaag
    28021 cacgagtttc tttggaaaat caatggggaa tcaatacttg gcttgttttc ttatctataa
    28081 tatttacgag cgtcatccag aacttttttg acggtttcag tccttttccg gaagaaagca
    28141 tgcagcagca cttattgagt tttctagtcg ataatttact tttattcgca ttcaactatg
    28201 cattgtttta cattgcgcta gtagttgtac ggggtggcag accaaaaagt aaccttttat
    28261 tttcagtttt ccaaagaaag tattttggtt cgatacttgg catcaatttg atcaattcag
    28321 tcatcaactg gctactcaac agtttaatct ttctgcccat gtttttaatc agcggagtga
    28381 gtacttatat gcagctgctt ttcagttcaa atgcggtacc tacgggtgtc atgccagaag
    28441 attttcttga tatcagcttt gttttatcga tgatagggat gatttttgtt tcagcactca
    28501 tcatgagtat tgttggcggt ttattccaat ttgctgcatg gacaaagttc gactatcctg
    28561 atttgtcggt tattcaatgt ttgaaatatg gctggttttt attgaaagat agaattggta
    28621 cgtatatttt gttgcagctg tcttttatcg gctggtattt gctaggagca atcgctttgt
    28681 tcatcggtct tttgtgggtc attgtttatg tgaatgtgtc agttgcagaa ttttatgaac
    28741 aagcacggat tgaaaaagga ggtccagacg cctattttac ttagcatgta agcagtttat
    28801 tcatcaaaaa aataactttt gtggtaggat aaatctttga gggggaatgt acgatgaaat
    28861 taactgtttt aggatgctta ggagcgtatc cttataaaaa tcaagggaca acaggttatt
    28921 tgcttcaatc tgacgggttc aatttgttga tcgatgcagg tagtgctacg ctgatcaaat
    28981 tacaagaaca ccttgatcca cttgatctag atgctgtgat ccttagccat tatcatcatg
    29041 atcatattgc tgaccttggt gtattacagt attactggca acttcatcct aagagaaatc
    29101 cggagacatt gctttcaatt tatggacaca caaaagattc cattcacttt gaagaattga
    29161 cgttggaaaa tgtctcaaaa ggacatcctt attttgaagc tgaagaatta aaaattggtc
    29221 cttttctgat tacttttatg gaaacaatcc atccagtagt atgttacgcc atgcgtatcg
    29281 tagaagaaac aacggggaaa gtattcgtat ttacaggtga ttcaggttat ttggaaagtt
    29341 tcgctgattt tgcgaaagat gctgatttgt ttctagcaga tacctatctt tttgaaggaa
    29401 atgaacatca tcatgcccat ttcacttcaa aagaagctgg agaacttgcg aaatcagcta
    29461 acgtaaagaa acttgtactt acacacctac ctcagtttgg tgatttagaa caattgaaaa
    29521 atgaagcgca aaaggcagca ggcaaaggga ttgatataga acttgctgca gttgacaaag
    29581 tgtttaacat ttaggaggaa gaacatgatt tttgtaccaa atgaaaacca cgacccaaga
    29641 atcaatttag caattgaaca atatttgctg caagaaatgc ctttagatga acctattttg
    29701 ctcttttata tcaatgaacc ttcaatcatc atcggcagaa accaaaatac gcttgaagaa
    29761 atcaatcgag attatgtgga agaaaatggc attcatgttg tccgtcgctt aagtggaggc
    29821 ggagctgtct accatgattt tggaaacctg aactttagtt ttatcatgcc tgatgatggg
    29881 gattcattcc gtgactttgc gaaagtaaca cagccaatca tccaagcact tcatgaattg
    29941 ggtgttgctg gggcggaatt gaaaggccga aatgatctag tcattgatgg catgaaattt
    30001 tctggcaacg cgatgtatgc taccaacggt cggatgtttg ctcatggaac aattatgttc
    30061 gactctgata tcaatgaagt agtcaatgca ttaaaagtaa aaaaagacaa aatcgaatca
    30121 aaaggaatca aatcgatccg ttctcgtgta acgaatatca aaccatttct tccagaagaa
    30181 aagcaaaaaa tgacaacaga agaatttcgt caagaaatct tgttgaaaat tttcggcgta
    30241 gagtcagtag aagaagtaaa aacgtacgaa ttgactgatg aagattggaa aaaaatcaat
    30301 cgaatctctg aggaatatta tcgaaattgg gattggaatt acgggaagtc tccagatttc
    30361 aatttctctc gccaaaaacg tttttctatc ggttcgattg aagtccattt gaatgtctca
    30421 gaaggaatga tcaaagaagc aaaaatcttt ggcgatttct tcggactagg agatatctct
    30481 gacgtggaaa aaaaattggt tggacagaaa tatgataaag catctctatc aaaaatagtc
    30541 agccaaattg atgtgaagaa atattttggt gcgatagaac cagaagaatt gcttacctta
    30601 ctttattgaa aataaaaaat agcggaatcc acatatatgg attccgctat tttttataca
    30661 ggattcgggt aatttcgaga gagttgaaca gtgatccgat caatgaaagt atctttttcc
    30721 tgcgttagtg ttcctgtgta acgatccgct acgtctttca tcatcattaa gtcaaaacgt
    30781 tcctgatcat ctaattcttc tgtgatgcct cgactaaata ggtttgtatc gtaatgtgca
    30841 ctatgttcgc aacaaatgac gaaatgttcc tcttgttcgt gtatcgacaa ataaattttt
    30901 cgatacagtg gattttcgat ggcatgagtt tctctaaagg aatgctctaa agcgtggatc
    30961 aaaagttgag ccagatcgtc atcgttgata ggaagttctt cgggaagatc tgcttggaag
    31021 gttatctgaa tattccgttt ggcagctaac ttctggtaac gcgctaagat aagatttgtc
    31081 acctggtggt tgcaaaaaga acacagcatt tcgaaatttt ttgcttcttc taatatcttt
    31141 tccacatagt ttttagcttt tgtttggtcc gtatgcatta aatcttgcag attctccatc
    31201 tcttggacaa attccaggcg aagtgtattt acttcttgga tatgctgtcg aagctgctca
    31261 taatgttgct ccaacaaatc atttttgatt tttaagaaat ctacttgtct ccgatctttg
    31321 tcggtattta agatgtgatc gattagattg tagctgataa taacgattag aatgataata
    31381 tataaaatcg tagaccaatt gatcgttgtt tgatagatac ctaatgccgt ttggatgtaa
    31441 atcaagcaat ggataatggc taccaagacg atccaaggtg tacaagctac ataaaaacgg
    31501 ttattcttat atgcttcgcc aatgcatgca agtgaagtga ctaaagtgct tataacacta
    31561 gcaatattag caatcggcat taattcagga agttctgcag gagtaaaagt tgcataaagc
    31621 agaacgccga taaaaatcaa aagttggaac gtacaaaaaa ttccgtacca ttttttatag
    31681 taaaacattc ggctccaata gtagcagatg atgaaagctg acgttaagat aataaataaa
    31741 tgagataaaa aagaatgaac gaatggttca aaaagaatac cacttaaaat atcttctgat
    31801 acagcttcaa atcctaatgc caaagcaaag caacttaaga gaataagtga gtattcaaga
    31861 cgtttttgtt tatacatcaa gtagatcgta tagaaaaagg tccctatagc gataaaaaca
    31921 gcgattatca tcgtcaatac ttgcggcact gattgtgaat aaataaaact aatcaatggt
    31981 ccagttgttc ctagataaac tttcggtggc agtccagcat agttctgata aggagatgag
    32041 actgtaaggg tcaatttttt tccgatataa tttgctggta aatctatcac agccaatgag
    32101 agtccgggat tgctttcttc ctgataatct ttccgttggt ataaaatctt ttcgcctaga
    32161 tatacagtaa tccattgatg gtttcctttg attagtaaat ttgcttcgtc caacggtttt
    32221 tcaagtgtcg tttccataat gaatgtttcg tctttatcca cggtaggaat cgtacgagtg
    32281 tacttgctgt caaacttaaa atcaggatca tcttttgtat agaaaaccca cgaatctttt
    32341 atttctttca tttgattgct gtccgcagga gaaaaaataa aataaaagaa ataagcaatt
    32401 cctgttaaaa ataacaatga taatataatg attatgctcc actttatacg taaataaaaa
    32461 gattcttttt tattatatat gttattaaaa aaagacataa aggtat
//
LOCUS       DAIGQM010000029        32225 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.029, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000029 DAIGQM010000000
VERSION     DAIGQM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.029"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(99..1229)
                     /locus_tag="NOA48_001350"
     CDS             complement(99..1229)
                     /locus_tag="NOA48_001350"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCI0789620.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="NOA48_001351"
     CDS             complement(1878..3080)
                     /locus_tag="NOA48_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0789621.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="NOA48_001352"
     CDS             complement(3140..3343)
                     /locus_tag="NOA48_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCI0789622.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="NOA48_001353"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="NOA48_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="NOA48_001354"
     CDS             4880..5692
                     /locus_tag="NOA48_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789623.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="NOA48_001355"
     CDS             complement(6716..6868)
                     /locus_tag="NOA48_001355"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0789624.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="NOA48_001356"
     CDS             complement(7059..7937)
                     /locus_tag="NOA48_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0789625.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="NOA48_001357"
     CDS             complement(7976..9094)
                     /locus_tag="NOA48_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCI0789626.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="NOA48_001358"
     CDS             complement(9091..11190)
                     /locus_tag="NOA48_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCI0789627.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="NOA48_001359"
     CDS             complement(11241..12062)
                     /locus_tag="NOA48_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0789628.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="NOA48_001360"
     CDS             complement(12059..12868)
                     /locus_tag="NOA48_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0789629.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="NOA48_001361"
     CDS             complement(12889..13383)
                     /locus_tag="NOA48_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0789630.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="NOA48_001362"
     CDS             complement(13395..13883)
                     /locus_tag="NOA48_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0789631.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="NOA48_001363"
     CDS             complement(13960..16656)
                     /locus_tag="NOA48_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0789632.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="NOA48_001364"
     CDS             complement(17084..18157)
                     /locus_tag="NOA48_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0789633.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="NOA48_001365"
     CDS             complement(18154..18981)
                     /locus_tag="NOA48_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789634.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="NOA48_001366"
     CDS             complement(18982..19788)
                     /locus_tag="NOA48_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789635.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="NOA48_001367"
     CDS             complement(19800..20885)
                     /locus_tag="NOA48_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789636.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="NOA48_001368"
     CDS             complement(20902..21444)
                     /locus_tag="NOA48_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0789637.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="NOA48_001369"
     CDS             21702..22691
                     /locus_tag="NOA48_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCI0789638.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="NOA48_001370"
     CDS             22688..23425
                     /locus_tag="NOA48_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCI0789639.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="NOA48_001371"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="NOA48_001371"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCI0789640.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="NOA48_001372"
     CDS             23989..24621
                     /locus_tag="NOA48_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0789641.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="NOA48_001373"
     CDS             24706..25353
                     /locus_tag="NOA48_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0789642.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="NOA48_001374"
     CDS             25358..26341
                     /locus_tag="NOA48_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCI0789643.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="NOA48_001375"
     CDS             complement(26744..28258)
                     /locus_tag="NOA48_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCI0789644.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="NOA48_001376"
     CDS             28396..29202
                     /locus_tag="NOA48_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789645.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="NOA48_001377"
     CDS             complement(29377..29946)
                     /locus_tag="NOA48_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789646.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="NOA48_001378"
     CDS             complement(30029..32089)
                     /locus_tag="NOA48_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCI0789647.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
BASE COUNT         9650 a         6750 c         5487 g        10338 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattatg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gttaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaa
//
LOCUS       DAIGQM010000030        31730 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.030, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000030 DAIGQM010000000
VERSION     DAIGQM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.030"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(284..751)
                     /locus_tag="NOA48_001379"
     CDS             complement(284..751)
                     /locus_tag="NOA48_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI0789648.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(871..2409)
                     /locus_tag="NOA48_001380"
     CDS             complement(871..2409)
                     /locus_tag="NOA48_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCI0789649.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            2489..3175
                     /locus_tag="NOA48_001381"
     CDS             2489..3175
                     /locus_tag="NOA48_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCI0789650.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(3376..3903)
                     /gene="msrA"
                     /locus_tag="NOA48_001382"
     CDS             complement(3376..3903)
                     /gene="msrA"
                     /locus_tag="NOA48_001382"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0789651.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(3987..4664)
                     /gene="pgmB"
                     /locus_tag="NOA48_001383"
     CDS             complement(3987..4664)
                     /gene="pgmB"
                     /locus_tag="NOA48_001383"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0789652.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(4661..5791)
                     /locus_tag="NOA48_001384"
     CDS             complement(4661..5791)
                     /locus_tag="NOA48_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0789653.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(5791..7974)
                     /locus_tag="NOA48_001385"
     CDS             complement(5791..7974)
                     /locus_tag="NOA48_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0789654.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(7971..8996)
                     /locus_tag="NOA48_001386"
     CDS             complement(7971..8996)
                     /locus_tag="NOA48_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0789655.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(9041..9868)
                     /locus_tag="NOA48_001387"
     CDS             complement(9041..9868)
                     /locus_tag="NOA48_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0789656.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(9865..10932)
                     /locus_tag="NOA48_001388"
     CDS             complement(9865..10932)
                     /locus_tag="NOA48_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCI0789657.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(10958..11794)
                     /locus_tag="NOA48_001389"
     CDS             complement(10958..11794)
                     /locus_tag="NOA48_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0789658.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(11791..12660)
                     /locus_tag="NOA48_001390"
     CDS             complement(11791..12660)
                     /locus_tag="NOA48_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0789659.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(12730..14013)
                     /locus_tag="NOA48_001391"
     CDS             complement(12730..14013)
                     /locus_tag="NOA48_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0789660.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(14027..15712)
                     /locus_tag="NOA48_001392"
     CDS             complement(14027..15712)
                     /locus_tag="NOA48_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCI0789661.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            15987..17012
                     /locus_tag="NOA48_001393"
     CDS             15987..17012
                     /locus_tag="NOA48_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0789662.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(17607..21281)
                     /gene="rpoC"
                     /locus_tag="NOA48_001394"
     CDS             complement(17607..21281)
                     /gene="rpoC"
                     /locus_tag="NOA48_001394"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCI0789663.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(21339..24956)
                     /gene="rpoB"
                     /locus_tag="NOA48_001395"
     CDS             complement(21339..24956)
                     /gene="rpoB"
                     /locus_tag="NOA48_001395"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0789664.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            25684..26652
                     /locus_tag="NOA48_001396"
     CDS             25684..26652
                     /locus_tag="NOA48_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0789665.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            26670..27575
                     /locus_tag="NOA48_001397"
     CDS             26670..27575
                     /locus_tag="NOA48_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789666.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            27572..28378
                     /locus_tag="NOA48_001398"
     CDS             27572..28378
                     /locus_tag="NOA48_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789667.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            28514..29503
                     /locus_tag="NOA48_001399"
     CDS             28514..29503
                     /locus_tag="NOA48_001399"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCI0789668.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(29820..30344)
                     /locus_tag="NOA48_001400"
     CDS             complement(29820..30344)
                     /locus_tag="NOA48_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCI0789669.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            30631..>31730
                     /gene="scm"
                     /locus_tag="NOA48_001401"
     CDS             30631..>31730
                     /gene="scm"
                     /locus_tag="NOA48_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI0789670.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTT"
BASE COUNT         8909 a         6858 c         5971 g         9992 t
ORIGIN      
        1 caacccctta ttttgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat
       61 atccataaaa cataagaagc tgttttttaa aattgtttct tgtgactcgg agctgaacgg
      121 caggcttaca acctcttggt aaacggtgtt caatcagctg accctcggta ttagctcaaa
      181 aaacggcaaa atatgaggaa ctattttgac gtttgtttct ctaatactca ggtcaaaacg
      241 ctgatttcac aacctctttt tcggtcaagt tcaacaacag tttttacgcg tcgatctctg
      301 gcgctttgcc caaatgagct tggatcatcc agatacgttt ttctgtggct gttttgaatt
      361 cgataaagat atcttgtgtt ggatcgtcgc cttcttctcc agaaacttcg attccttttt
      421 ggtaaagatc tgctagataa cgatagcctg caacaagtgt ttccaaacgt tctggaatag
      481 tacgatccca gcggccaatt tcatcaggga tttttgtgtt atctgcaaat tcacgcaatg
      541 tagaataagg tgaaccgtct aatgtgatca agcgttcgga tacttcatct aactgagcgt
      601 tcaaatcatc catgaactca tccatcattg ggtgcaatgt aaggaaacct ggtcctctca
      661 tgtaccaatg tgtttggtga acaacaacag acatttggct tagatctgca actaattgat
      721 ttaatacttc tttggtttgt tggaatttca tctttcttgc ctcctaacat tttcttacac
      781 ttaaaataat agtagacttt caatgaaaag tacaacaaaa tcatttacct gagaacgatt
      841 ttcagttcgc ttttttatcc gtaaagccaa tcatttttca gaatcagcta attcttctcg
      901 cagttgagca aattgctgat aagtctgtgc taaatgcttt tgtgtcgaaa caaataatgg
      961 atagattttc tgatattttt tatgatcagt ttcttgtact ccaacttgct ctttcaattc
     1021 tatcaattcc tgtgcttcac tgatactttg gatctttccg atgcttctcc agcctaaaat
     1081 cacagctcct aatgcggatg cttctgtgac agtagggaaa acaagcgggt aacccagtac
     1141 atcagccatc atctgacgaa aaatcggaga ttgagcaaac ccgcctgtag cacggatctc
     1201 tgtgagctga ttttcctggc aaactccttt taaaatccga taaaggttga gacagatccc
     1261 ttctagaatc gccttcatca tttctttttc tgtatgttgc cgctgtaaac cgataaaact
     1321 gccaaacgca tctgcgtccc aaagcggtgc tcgctcacca agtaaatagg gatgaaaaat
     1381 cagaccattg gcacccgctg gcacaaaagc gatagccgaa agcagtgcat catatggatt
     1441 ttctcctttt tctttagcag attgaacgac ttcctgtaaa aatgtatgcc ctgcccaatc
     1501 aaagatgcca gcaccattgc tagtcgctcc tcccactacc caatgtttct gatccagaac
     1561 ataacaaaac gtctccattt ctggatggaa ctgaggctga gtagtaataa aacgaagtgc
     1621 tccgctcgtt cctacggtca aagcggcgat cgtatcacca aaagcaccta accctagatt
     1681 agaaagcggc ccgtctgccc ctcccaaaac aaatgatata tcatttggca aacctagttc
     1741 tgctgctgtt tttgatggta gacctgttac ttgataggtg gaaggaaaga cttgcggcaa
     1801 ttgctctatt cgaatgttca agtagtcaag cacttcttct gcccattgga attcatggat
     1861 atcaaaatat ccagttcctg aagctgttcc gtagtcgctg atcagttcgc caaacaatct
     1921 ataaaagata tagtctttga taccgacaaa ataagcagtt tttttgaata attcaggttg
     1981 gctgttttgc agccacttga ttttgttcaa tggtgtcatt ggatgaatcg gcgtcccagt
     2041 ctgccgataa aattctttgc caagcacggt atatttcagt ttttctgctt cgtccgctgc
     2101 tcggttatct gcccaagtga tcattcgaga taacggtgtt ttctcttcat ccaacaatat
     2161 caggccatgc atcgcagagg agaaggagac aaattgaatg attgtgtctg aaggcaactg
     2221 tttaattact tcttttataa cggtgcagac accttgaaag atcaattcct gatcttgttc
     2281 tgccatccct tgtgtttctt ggatcaaagg gtagcgaaaa taagcggatg ctgcttcttg
     2341 ggcttcatct gtgaaagcaa ctgctttggt ttgtgtggtt ccgatatcta atccgattga
     2401 aacgttcatt ttttcacctc aaattttatg tatgtacaaa aatttagttt aagcttgcgt
     2461 atcttggttt tgaaaagggg gagatggcgt gttactttat tttatcattg gttgctgtat
     2521 cggatcattt ttatgtttaa ccgcccagcg gattccgtta ggtcactcta ttatttatcc
     2581 tagatctcat tgtgtcaaat gctgtcgttc gctttcttgg tatgaattga ttccgattct
     2641 ctcgatcatc gtccaacgat ttcgctgccg ctattgcagg tgtcggttgc ccttctacta
     2701 tttgttggca gaagccttat gtggtggtct ttttgcctgg ttctttactt tttcttccgc
     2761 aagaaatttt tcgacgttca tatggatgct ttcggctttg ctattttcgt tgatggattt
     2821 attttacttc atggtccatt ctcacacgct attctgttct tgggcaattt tatggatttt
     2881 ttggttgcag gccggcgtct tccaatggca aagtgtgctg ttaacgttta tcgtaggcgg
     2941 tgtgtgcctt cgctatggtc aatcctatct cggagctggc gatactctgt tgatgctttc
     3001 ttggagtggt ggcttgtctc tagaagagtt gcttcagatc ttgtttcttg ctagtctgtt
     3061 tggaatatcc gttttttctg tttactttat ctgtcataaa aaaaagttgg aaaagctgcc
     3121 tttcattcct tttttgagca gtgcgttgct gattgtcctt catcttaggt attgaaaaaa
     3181 ggttgtgaca aacgacttgt cacaacctct gatatatagt gttctcttac caaatccttg
     3241 tgacttggag ctaggcgaca ggttcacaac ctctccacta aatggtgttc aatcagctga
     3301 ccctcagtat tagctcaaaa tgctggtttt acaacctctg atatacggtg ttccataagt
     3361 agctttttcg gcttcttatt tcttgacgcc ccaatgtcga cgaaggaaac ctgcacgtcc
     3421 agaaccttct cgataaagat tgtaatggag cttgtttttc ttgtaataat cctgatggta
     3481 atcttctgca ggataaaatt cgcttcttgg ttcgattttt gtcacgattg gcttatcgaa
     3541 tcgcccgctg tcttgcaatg cttgttttga acgctctgca atatttcgtt cttcttcatc
     3601 attatagtag atcactggac gataagaatc accgcgatca gcgaactgtc ctaatgcgtc
     3661 agtcggatcg gtttgctgcc aatagatttc caccaactga tcataagaaa taacttctgg
     3721 atcatattcg atctctactg cttctgtatg ccctgttgtg cctgttgtta cttgttcata
     3781 agttggattt ggtacatgcc cgccagtata accggatgtc acagaaatga tccctggctg
     3841 ctcttcaaat ggtttgacca tacaccaaaa gcatccgcct gcgaaaactg ctttttttgt
     3901 catataaaat cccccttttt tctcatcata ccttgatttc caaaaggagg ataacgtttt
     3961 gcttgtgaca gaaaaaacgg aaactattat atacgtgata cggcttctga taaatgccaa
     4021 aacgaacgta cttgatcaaa aacggttaaa tcaggaatca catattcagc agaaggaaga
     4081 tttatgtttt cacctattcc caatacatgc atgttaccag ccaaagctgc ttgacaacca
     4141 gcttctgaat cttcaatgac caagcatgca tttggcggta cattcaattg ctgtgctcct
     4201 ttgagaaaaa cttctggatc aggttttgct tttgatactt gcgtgccgtc aataaggaca
     4261 tcaaaataac ttgtcaaatt cgttttttct aaaatgaggc gtgcattttt gcttgctgat
     4321 cccaatccga tcttgatgtt tgtttttttc aagtactcaa gaacagctat tgcaccaggc
     4381 aaaacggatg tttcatccat tttttgaatc gcttgaagat atagattgtt tttttgctca
     4441 gcaaaggctg atttctcttt ttctgagaat ttctgttcca tttttccaaa tgacagcaat
     4501 cgctctagtg actcggttct ggatattcct ttcagttgct cgttttcttt ctcagtgaat
     4561 ggaatggaca gctggttagc taaaaccagc cacgcttcgt aatgataacg agctgtgtct
     4621 acaagaacgc catctaaatc gaatagtgct gctttgattt tcatcgatta cctccttgaa
     4681 aatgaacgac ttgaagtaaa gatgcgatgt ttttagctgt gcgatgaaga ttatcagtgg
     4741 cttgctgtaa agcttcttgt aaaggcacag ctgcaggaag gatcggaaaa acggccgaaa
     4801 tgccaacatc tgctgctttt tcgcttcctt taccaacact tccgcaaata gctatcacag
     4861 gaacgccctc tggtactctt ctagcaatcc caactggcgc ttttcctttt agactttgtc
     4921 catctagacg tccttcgcct acgattacga ggtctgcttg ctgtacccgt ttatcgaact
     4981 ccagtaaatc caatacgtag tcgatgccag agactatttt ccctgaagca aatgctaaca
     5041 gtcctgcacc cattccacca ccagcactac tgcccgatgc ctcgattact tgaggggcaa
     5101 atctcatata aaaatcatgc atggcttggt cagccactgc taattcattt tctttcaagc
     5161 ctttttgtgg tccgaaaaca aaagaagcgc cttcttttcc gcataaaaga ttagtaacat
     5221 cagtaatgac agtgattttg gctttaatca gctcaatagg cacgttcgtt ttatcaactg
     5281 tagcaatttt acctagattt tctcccagtg cttctacttt ttgattatct tgatcgtaaa
     5341 aagcataacc tagaccttct gccatgccga tgccgccatc gttggtacta cttccgccaa
     5401 cgccgatgat gatgtgtcga acaccttgtt gcaacaattg tcgtatcagt tctcctactc
     5461 ctcgcgtgga taacctaagt ggctgttgtt ggtttagtgg gacatctttc aatccgacga
     5521 tttctgccat ttcaaaaatc gcagtttgac cgtctgaagc gtactggatt tctttgtttt
     5581 tgccaaatgc attagtaacg actgctgttt gccgcttcaa ccttaaactg tctgctaatg
     5641 atgaaaccgt tccttctcct ccatcgccta taggtagcag atcatattca gcctgaacaa
     5701 aaacttcttg aaaacctgat tgaatggctt gtgctgcctc taaggctgtc agactttctt
     5761 tgaaagaatc tggcgcaatc agaatacgca ttattttccc ctccgttcca agatcagttc
     5821 tttttccagc tggtattggt ctccattgac aaaaataggt aatgtttctt tcgtctcttt
     5881 ttttattact atttgttttt ttgtcaaaac aaatagcaac ctgtgatttt tccaaataaa
     5941 aggaaaagaa attttttccc atgctgaagg aagtcttgga gaaatagaaa gagttccatt
     6001 cgttactgta atacctgaaa aaccaaatat aactgctagc catagtgctc ctaatgaagc
     6061 agcatgaatt ccgtcatctg atgaatgcgg atctggtcct aaatcaatca ggcacgcttc
     6121 ttggaataaa tgatacgccc attccatttc ttggatacgg caagcctcta tggcgtgaat
     6181 cgctttactc aacgatgagt cgtggattgt tttgttttca tagtaatgca aattcttaga
     6241 aacgattggt tgagaaaaat actcaggtaa taagtataac agcatgacaa gatctgcttg
     6301 cttgctgact tggagttcat ttacttcgct acgggcataa tcaagtaaaa tagactggct
     6361 gccaggacgt tctttgtaag tggtcaaatc aataactggc ttactgagat acgtgtcatc
     6421 ttgcggaatc agctgttctt tgttaggcac tggcaaatat aacttatcta aaaaattttg
     6481 acattctttc aaaaaaagcg gatcgccagc ttgatattta acagctaagg ccacattata
     6541 atgcgccaga tagttcgtat atgcattatt gtcgatatat tctgtgtatt catctggacc
     6601 aatgactctg tgtatctcta aatgatcatc gacttttaca gctctgctca gccaaaaagc
     6661 tgctgtttca tgaatgagcg tttttccctt tgtttctaaa aacgattgat cctctgttgc
     6721 ttggacatac tcttgaacgg cataagcaag gtctgcactg atatgatgtt ctgcggcagc
     6781 tgaagcaact tcttgtcttg ttccggtttt gatattcaat gcagcaaatt tgggtgtctc
     6841 ttcctgacca gtgtgtgcgc tttcccatgg gaaaagtgca ccttgatagt gataatctct
     6901 tgctttttgc cgtgcgcctt ctaatcgatc ataacggtac agcagcaaat tctttgctac
     6961 ttcaggaaac tgatataaaa agaaaggcag gataaaaatt tccgtatccc agaaaacatg
     7021 ccctttataa ccttcgccag ttagtccctt cgcccctaca ctaacacttg gatcattgcg
     7081 gggagtcata atctgtaaat ggtaagcagc gaagtccatc gctaactgat cgaaagaaga
     7141 atcgccttgg atcgttatcc gatgctgatg ccaaaaatct gtccaataag acatcgactg
     7201 ctctaaaatt tctgtataac taacgctttt ctgggcttgg gcaatacttt tcttaaacgg
     7261 gtctgtttgc tgaagagagg tagagagcac gatgatcttc tccagcgtaa aggacgtatt
     7321 ttttctgatc ttttctgaaa aggaagcggt gatccggcga ttttttgctt ggaatacacc
     7381 tgctttattg aatttagctg caatcccaat atcaatttta ctttctgttg tctggtagga
     7441 tgcactgatc aaatcgtcac caaatactcg cagttctttt tcaaccaact gctgtgtacc
     7501 aaaattggtt tgctgtccat cgatacccgt tttcacatct acttggcagt cttcggtcaa
     7561 cggcttgatg accactttca gggctgcctg atggagatta ttttgatcag caacacgaca
     7621 agtaatgact tccacttttt ttccttgagc agtttcaatg agcgcatagc gtttaagctc
     7681 tcccatttct aaatctagtg cccgctcgta tgcaagaact ttcatcgtct caagagaaaa
     7741 atgttcaccg tcgattttta tttcccatct gatgacatct gggagattca ctaactcggc
     7801 tgattctgct cctaaaggtc ggttatatac accagctgca aacattcccc ttacttgatt
     7861 ccgatagtct tcctcctggc ttcctctgat accaaaaaat ccatttccaa tggtcatctg
     7921 actcgcatac ttattgatat actctaaatc aaactgtttt tcttctactt tcataaggta
     7981 ataacttctc ctgtttctgc cgaacgatat aaattttcca ccagattctg gatgacatat
     8041 ccttgccagc catctgcaat catctgagtc tggtcaccga gcgcccgatt cacaaaatga
     8101 gccatactta gttcatgtgg gtcattaact ggcgtggtct tttgtaagga aaccagcttt
     8161 ccatctacat cttcgaatag ttcgcctgga tacagattag cacctgcctg atcgccacaa
     8221 aaagccacat tcagtttgtc ttctctgata ttcaaagcaa acgaagtatt cagttggatg
     8281 atcttgccgt tttctaattc cagtgtgcca aaaattgcat cttctactgt gaatttgctt
     8341 ggatcccatt tcccgaattt ccctgaattt tttttcgtac caattttttg gaagctgtac
     8401 gcccgaacgc tttttacttt aggaaatcca gtaatataca tcgctgtatc aagcatgtga
     8461 atgccataat cgatcaaagg cccgcctcct tgaagttctt tgtcgataaa cgttccccag
     8521 cctggaacac cagaccgacg aagcgcattc gcttctacgt aataaatatc cccgagaaca
     8581 tcaagatgat tcttgatcat tgttgcttcg tcagaaaaac gatgctggaa tccataagcc
     8641 aaaatctgcc cgtttttatc ggctgtctct gccatctttc ttgcttgatc agctgtcata
     8701 gctggtggtt tctcgcacat cactgaagca ttagcttcga gggcagccaa tacatgttcg
     8761 aagtgaaagc gattgggtgt acagacactc acgatatcgg gagaaatctc attcagcatt
     8821 tgtgtaactg atgtatacgc atgagaaaat cctgtacgtc ggcaaaagtc ttctgctcgc
     8881 tggctgactg gatcaaccac agcggccaat tctaagacat ctgatctttt ttgataataa
     8941 gcagcatgta ctttttctgc tacttgtcca gcgcctatga ttgctacttt cttcatttat
     9001 ttctctctcc tttgcttatt tacttattgt tattctttct ctattctttc tctaaatcat
     9061 ttaaatgacg cgctgtttcc agacagtttt tcaagtattg caatgattcc tgataaattt
     9121 tcacttcatt ttctcctcgc aaacgacatt catataccat ataaccttca tactcatttt
     9181 gaagtagcgt ttgaaaatgg cgagtaaaat caattgcgcc agatcctggt tggtagcgat
     9241 gattatctgc taaatggata tgacccacat actctttttg cgtagtcaat gcttttgaaa
     9301 tatcatcttc ttcaatattc atatgataaa aatcagcgat gatctgcaca tgtttcaatt
     9361 gattagagtc aatgtaatga cgcgcatccg ctaacaaatt gatcatatgg tcttggtatc
     9421 ggttcaaagg ctccaaataa ataaccgtac ctgtttcttc ggctacttta tctaaataac
     9481 gaagtgattc gctgactgct ttatagtctc cttctttgct tcggggtgaa accatcggcg
     9541 gtaatcgata agtgaacatt ccccaagctg ctgggataac gattcctttg cctccaacct
     9601 cgcttagtgc acgcaaaatc tcagcaattt gacgtacacc attaagacgc cgttcttcga
     9661 taaagtcacc gatccaccca tcgtagccgt tacaagctgt cactactggg atccctgttt
     9721 ctttgattgc ctgtttgact gtgtcgatat tttctattaa caacttaccg tcgatttcgt
     9781 attcttcaaa tccacagtct ttgataaatc taaatttttc taaaatgtct cttgggaaaa
     9841 atgcttgatc ttgcgtaccg aatttcattg ttctcctcct cggacttgaa cgcccatttt
     9901 gatactttct tctgggtgct ggtctacata acgcatgtaa gcttctgcgc tttctgcaaa
     9961 tggcacaact ggatcaatga tttcttcaca atccaagtaa ccgttcatca ataattccca
    10021 acatgtgtcc tcgattcgtt tacggttcca tcttgggtaa tctgggtttg gttcactaga
    10081 tgctcgagca aagacgattt ttgcattatt gaaatgtgct tcgcgaccaa gattaaaccc
    10141 agctggaaaa ggtttagcaa aggcaacata agaaatgatc ccgccatagc cgatccctat
    10201 taaagaagct tgtaatgcgg cagcactgcc actcgtttca ataactgaat ctactccacg
    10261 tttatctgtc aattccttta gacgaaaacc gacatctgct ttcataggat ctagcgtgta
    10321 atcggcaccg tgtttttctg ctaattctct acgctgcgct atgggatcga tcccaacgat
    10381 ggtagtagca cctgcttttt tagctaattg aatcgcaatt tgcccgatag cgcctaaacc
    10441 gaagattgct acagcatcac ctgctcgaac atgtgcttcc cggataccac ctaaagcgaa
    10501 ttgagcagga tcgtaacata ctgcattttt ccattgatcc aaccgatcaa gtttacgtag
    10561 tttataatta tcaacaccgt ttgtaatcag cgtttcacga atgggtccat aagtgcagac
    10621 taactctcct ttttgatact ctgtcaccaa actgcccgtt tcttcgatcg taccgacaat
    10681 catatttcct aattgaaatt cgccaaatac cacaccgcgt tggcttcctt cttctcttgg
    10741 caagaatagg cgccattctt ctgaaaattc ttcatcgata aatggactta atcctctaaa
    10801 gtcgacaatt tctgttcctg gttttggagt agcgaaaatt actcggatac gtacttcgtt
    10861 cttttcgatc tcacggtctt cgtaatcttt gaatccggct attcttggtt ctaatgcaac
    10921 taattttttc atcttttctt tcctctttct tttcttttta tccttttacg ccgccttcga
    10981 ctaaatcacc tttaataaat cgttcagata acgcatacat aatgatgact ggtaaagcgg
    11041 tcaccaatga agcggccatc attcgtcccc aaatgtagtc tggtgtactg aataatgtgt
    11101 tcaaaccgat tggtaaagta aatttttcgg aggtcgacag gaaaatcgaa gcaaataaat
    11161 aatcattcca cgaaaccata aagcaataaa cgaagacaga aatgattcca gaaatagcca
    11221 atggtataat gatccgaata atgatctgga tccggctaag accatcgatc attgctgctt
    11281 cttcaatatc agtcggaatc gtgtcaaaat aactttttag catgaatatc gcagtaggaa
    11341 gtgtttgaac gaccatcgtg ataatcagtg ctgtattggt atcatacaaa cctagaccgg
    11401 aaatgatttt aaataatgga acaacgatca aaataccgga aaacatataa acggtgtaaa
    11461 agctagcatt gattttcgag cgagctttga agcgtagttt tgacaaagcg tatgccccgc
    11521 tgatcccaat cactactgca gttacggagg ctatcaagga gatcactaaa ctatttttga
    11581 aatacatgat gaatggaaaa atctcagcat tgaaaatatc ctgataatgt tcaaaagtcc
    11641 attctttcgg aaaaatagtt tgtgtcgttg caattgcttc ttgtgaatcc ttgaatgatg
    11701 tcatcagcat gatcaaaaat ggaaacaaat tgacagctaa tagcaacaaa atcgtcgcgt
    11761 aaaataagat tttcctgctc tttttatttt tcatttcaag tccaccttct ttcgtgagag
    11821 caagacgacc gctgcaataa tgatgaacaa tagaatcgat atagctgctg cttttccaag
    11881 atcattgaac gcaaaggctg tctgatacaa ataaacgcct aagatattga ctttattcgt
    11941 cagtagatag acatctgtaa acatatagaa catccagata gatcgtaaaa caatcacagt
    12001 tgctagtact ggtttgattg ccggcagtgt cacgatcttg aacttctgcc aagcatttgc
    12061 accgtccatt tcagctgctt cataaagcgt tttgtcgact gtttgcaaaa tagccaaaaa
    12121 tgaaataaac gcatacggat agtatctcca gatagcaaac aaaacgacca taaagaagct
    12181 agcaactggc tggtcgaacc acagcggtgc ttcgttgaaa agctgcaacc tatctactaa
    12241 cagatcattg acgattccat aactattatt gaacatatat ttccaagcaa aaatcaaaga
    12301 aatagatggc gtaacataac ttaataaaat cagtgaacgc accgttttcc taaatctgaa
    12361 cttgcggtta agcaaaatag ctacggctaa tcctaaagct gtactgcctg ctacaactaa
    12421 gaatgtgtaa gcaactgtta aacctaaaga acgataaaat tcactatcac ttaaaatttc
    12481 aagataattg cttaatccga taaaaacggc gtctgagtta ggattcagcg gcatatcgaa
    12541 aaaactgatc tgaatattgg aaagcattgg aatcagcact aaaacagcta ataaaagcat
    12601 gcttggtgct aaaagtccca tggctaattt taagtcagaa tgtttccttg gacgattcat
    12661 tgaaacctcc ccctgataat ctgccaatag ctatctactt ttttcgaaca ccattggcag
    12721 aacttcttgt tatttcgtat ttttttgtgc gtcagctaaa gcttgatcga catcttcgtt
    12781 tccgacagtt acttggttca ctgcttttcc gatcacacct gagcttgtga tatctcccat
    12841 tttcgtgaaa ttcttttccc cgactagtcc aaagacttgt acttcatcaa aagcactagc
    12901 aatctcagat ggcagctcgc caaaagactt gatgacttca ttttctttgt aaccatccag
    12961 ttcgactact tgtttattca ctggttgagc accaccagga gacatcaaga cccacttttc
    13021 catgtttttc ggttgagata agaaagctgt gaatgcttca gcagcctctt tttgtttctc
    13081 gtctagacca gaagaaatcg tcaatccaga tactgtgcca tagacagctt gatctttttg
    13141 tgttgggata gcaaaaccga tattttctga gttccccgct tcataaacag aaggcaaaat
    13201 gtaagttgaa tagattgcca ttggtgctgt tccattcatg aaagcatctt tgatttctgt
    13261 cacatcatta gagcctggca tcgtgtattg ggataagttt tgataaaacg acaatgcttc
    13321 tctcatcttt tccgtatcga tcgttacctc gccttcatca tccaaaacat ttgctccatt
    13381 tgacaaagca aattgagaga acgcttgctc actcattgtt ccttcagcag taggcatagc
    13441 aattccatat tgtttattct ctttatctgt gaaatgttga gcaattttta aaatatcatc
    13501 ccaattttct ggttctgaaa aaccagcttc tgataatttt tctttgtcat accaaatacc
    13561 ttgaacccag ccgctaattg gtgcagcaat atagcttttt ccatcttctg aacgaacaag
    13621 gtttttggct ccgtcataat aattatcttc tccagcttcc tcgataacgt tttggactgc
    13681 cgtctgatca atcagttcat ctttatccat cactttagca aaatcctgac tgacttccat
    13741 tacttctggt aatttaccgg aacgagctaa cgtaacgatt tttgtattga acgctgattc
    13801 ttctaccggc acttgcttga ttttgatgtc tggattttct ttttcaaaat cagcaaccag
    13861 ttcattgatc acacttaatc gttcctgttc gacagaagag tgcatgaatt gaatcgttgt
    13921 ctgttgtgat tcgttagagc tttgactttc accacaagca gtaagaagaa atccagtagc
    13981 tagcagacag gtagtaacaa taattttttt catttttttc cacctcttat tttattattt
    14041 tcagccacat atattcatac ggctggaata tcaactttcg ttcttgactg caatggataa
    14101 tttgtccaga aaacaggtct aggtaatctc cttttggtaa aagataacct gctgattgat
    14161 tggaaaaatt atggataact aagactttct cttccttcgc ttcgcgaata aaactgataa
    14221 aagaatctgc tgagtccagt aagtaaatca aactattcgg atggaaggct ttttcttttt
    14281 ttcgaataga tagcatctgg gtcaattcac catatactgc tgttcttaat ggatctgtct
    14341 gcaactcttt ctcaatatct gctaacaaaa atttttgccg attgattttt cgattctctc
    14401 ctgttttttc tacgcctttg taatcatttc gacttcccag cacactttga atataaattg
    14461 ccggcacgcc tggtaacgtt accaaaaatg aatgagcagc taaaaagcgt ttgcttctcc
    14521 attccgtcgt atctgttgga gaacttaacg catctagata cgtagcgttt atctcatatg
    14581 gactggtcgt tccatctggg tttttcttgt agtttactcg ggcaccctct ttcttcagct
    14641 gttccactaa ttcaaggatc gttttttccg gcagaatacc tcgtaccgga ttcaatccga
    14701 taccgtcatg ggaggctaaa aaattaaaaa aagttgtttt tttcgatgcg aaatcgatgg
    14761 tttttaacca ttctttcaac ttacttgtat tacccgaacg aatcgcttga agggtcaaag
    14821 gtggtagcga aaactgatag accatctgtg cttcattctc gccattccca aaataactga
    14881 tattatcttt gtgtggcaca tttgtctcag tgatcaatac cgttcctgga gctgcttcat
    14941 cagcgattgc acggaataat tggatgattt tatgcgtttc tggcaggtgt atacaagaag
    15001 ttcctagttc tttccataaa aatcccacag cgtccaagcg aataaatgaa gcgccttttt
    15061 ctaagtaaaa caaaagaata tcgatcattt tcaataaaac ttctggattt ttaaaattca
    15121 agtctacttg atcttcgcta aaagtcgtcc atacgtgttt ttctttcccg tttttgtcaa
    15181 tgaacgttgt aagtaacggg ctggtccttg gtctagtcac gctgcttgta tctgtatcca
    15241 gtggcaaatc aataaaaaaa tctttgtacg tatcattcaa gtttaaatat tcctgaaacc
    15301 aagtactttc ggcagacata tgattgcaga caaagtcgaa cattaaccgt gtttcgcttc
    15361 tcatttcttc tatatcttcc catgtgccca aacggtcgtt gattgcctga taatttacaa
    15421 cggagaaacc atcatcagat gtatatggga aaaatggcaa gaaatgtaca actctaaatg
    15481 tatctgccaa atacttttga taaaatttct taaatgtacg caaagttggt tgctgctctt
    15541 caaaaaattg atccccataa gtaatcaaga aaatatcttc ttcgtcccaa tgcagtttgc
    15601 ctgcctggcc tttcttctgc tgataaacac tgactttttg ttcaatcata gaggcggttt
    15661 tctcagacaa atctgagtcg cgataaatcg cttgtaaaag ttttgtatac atcggattcc
    15721 cctttctttt ttgggagcgt tcccaacgat ttgatcatat tatggaaaac gcttactgtc
    15781 aatagcattt ttttaaataa ttttgatata cacaaaaata caaataagaa agcttatgta
    15841 tcaataatta atagcttctt aaaaaaatat ggtctctcat gatcatgcaa gctattccta
    15901 aattttcaaa atcatagaca aaaaagaatg tctattgtac tatggaatta ttctaaaacg
    15961 ctcccaaaaa ggaggtgcat ataaaattga aacctactat ttatgacatt gcgaaaaaag
    16021 ctaatgtctc aaaatcaact gtctccagag tattaaataa ccagccaaat atctctgata
    16081 aagcaaaagc aagtgtactt caagcaatca aagaattgaa ttatgaaccg agcaaaattg
    16141 caagaggact gtcaggaaat ggttttgacg cgattctagc attatctcat cgtacttctc
    16201 atacgaccta tggcaatcct tttttttcag atgttattca atccatttct gccgtttctg
    16261 aacaaaataa cttcgacttg attctacaaa cggcaaaaac accagaagaa gagctagaaa
    16321 aatgcgcgaa aaagatccaa gaaaaaatga tccgaggaat tattatttta agctctacga
    16381 tggatgaaac acttcttttt gaattggatc aatacaatat tcctattgtg gtaatcggaa
    16441 aagtcggaaa cgactacacg aacatctact cagtggacac ggataatttc caggatagtt
    16501 acgatttggt ggaaacactg atcaagaatg gacaccgtca tatcggctgt ctccatgctc
    16561 cgacagaagt ttatgtatcc aatgatcgtc tcaatggtta ccgtcaatgc ttatttgatc
    16621 accacctaga tatccgtaat gaatggatta tagacggcgg ctttcgctta gaagatagca
    16681 tggcagcaat gaatgattta atgaagctac gagaaagacc aactgcgatt ttttctaccg
    16741 atgcattaaa atcattgagt atttacaaag tggcagaaca atctggaaag cagatacctg
    16801 atgatctttc gatcgcagga ttcagtgatc ccttattgtc ctccctattt tcgccacagt
    16861 tgactcggat agacattccg acaaatcagt taggaatcaa agccacagaa cttttattcc
    16921 aactaatcca ccaccaatac cctgaagaaa aaagaatcat tctttcaacc gagattactc
    16981 tcacagattc gatccaacaa caagaaatgt agaacagaat tataaaagaa cagaaacact
    17041 gaggataagt cagttactct gttctttttt caatcactca tccctcgtta ccccctcccg
    17101 gtattttagc gaatttttct tattttccat ctgttttaga tagctgtgga taactataat
    17161 gtttgtgtta aactattttt tccacaggga agaaaaaact atttttaacc acgttgtgta
    17221 taagttttta tagttcgttt ttttaaacac atttaccctt atttcaatcc atgttatttg
    17281 gggatactta tctctaaaac ataaatagaa taacagacat gtctactggt tttgttttat
    17341 tcgaggaatt attcaataat agctagcaaa atattaaaaa taaccgctct atcttcccat
    17401 caatttattt tgcattcaaa aaatgatcta tctttacttt tgttgattga cttctcttgg
    17461 aagatgatcg ttccgatacc ttaattggat acgaaccgat gttgttaaga tcctttccca
    17521 cttttcttct agttagacaa attattttag acaaaccaaa aaagaggttg tgacaataat
    17581 ttgtcacaac ctctttttta aaatatctat tttgtttgat tgttcattgc gtcttctgca
    17641 gccatttgcg cttcaatatc tgaaatactg tagacatttt cgcttgctac accgacttct
    17701 tttggttcca tgtcacgata acgttgcata ccagtaccag ctgggatgat cttacctata
    17761 ataacatttt ctttcaaacc aagaagagga tctttcttac cgcggatcgc agcatccgtc
    17821 aagacacgag ttgtttcttg gaatgatgca gcagataaga aactatttgt ttctaatgat
    17881 gcttttgtga tacctagtaa gacaggtcga gaagttgcag gaacgcctcc tgagactagc
    17941 gtattgtagt tttgatcttt aaagtctgcg atgtctaata atgtacctgg taagatatct
    18001 gtatcacctg gatccattac acgaacttta cgcagcattt gacgaaccat tacttcgata
    18061 tgcttgtcgc cgatttctac cccttgcata cggtaaacac gttgtacttc acgaagcaag
    18121 tagttttcaa cagataatac atcgcgaact tgcaacaatt gttttggatc gattgatcct
    18181 tctgtcaatg gtgcaccacg gtggatcata tcgccttctg ctactttcat acgtgctgta
    18241 taaggaacag tatacgtacg tgtatctgtt tttcctttga ttgttacttc tttggtacgt
    18301 gttgcaggat cttctgagat atcgatgaca tcccctgtta cttctgtgat cactgcttgc
    18361 cctttcggat tacgtgcttc aaagatttct tggacacgag gaagaccttg agtgatatcg
    18421 tctccggcaa ccccacctgt atggaatgta cgcatcgtca actgagtacc aggttcaccg
    18481 attgattgag cggcgatcgt accaactgct tctccgactt caacgtcaga gccagttgca
    18541 aggttgcgtc cgtaacaatg tttgcagaca ccatgttttg tattacatgt gaagacagaa
    18601 cggattgtca ctgtttcgac acctgcatca acgatttgtt ttgcgatgtc ttcggaaatc
    18661 aattggtttc ctgcaatgat caattcattt gtttcaggat gacgtacttc tttacgggtg
    18721 taacgtccca ctaaacgatc ttctaatgat tcgatgattt catttccctc gcggatggct
    18781 tggatttcaa gacctcggtc agtaccgcaa tcttcttcac ggatgattac atcttgggcc
    18841 acgtcaacca gacgacgagt caagtaacct gaatcggcag tcttcaaggc tgtatcggtc
    18901 atccctttac gagccccgtg agttgagata aacatttcca agacggatag tccttcacgg
    18961 aagttcgaaa tgattggcaa ttccatgatt cgaccattag gagcggccat caaaccacgc
    19021 attccggcaa gctgtgtaaa gttggaaatg ttaccacgag ctccagaatc agacatcatg
    19081 aagattggat ttttcgcttc caaaccttcc atcagttttt gttggatgct gtcttttgca
    19141 gcattccaaa cagcaatgac acgttcataa cgttcgtcat ctgtgatcag accacgacgg
    19201 aattgttttg taatagtttc aacttgttta tgggcatttt caatgatttc ttgtttttca
    19261 ttcagtacac tgatgtcagc gatccctact gtgataccgg catgtgtcga atgtttgtac
    19321 cctaagtctt tcatacggtc aagcatctta gaagtttctg ttactttgaa tcgtttgaag
    19381 acttctgcga tgatgtttcc taagtttttc ttcttgaacg gtaatactaa ttcttgctct
    19441 ttgatatgtg caggaatatc agtaccagct tcaacaaagt atttgtccgg tgtttggacg
    19501 gtcaagttga agtctgttgg ttcattcaga taagggaatt caggaggcat gatctcgttg
    19561 aagatgatct taccaactgt tgtgatcatc gtacgttctt tttgccattc agtaaatggt
    19621 ttttcaccta atgagttagg gttcacaccg atacgtgaat gtaaatgaac atatccgttg
    19681 cgccatgcga taacggcttc gttttgatct ctgaagacca ttccttcgcc ttcgcgtcct
    19741 tcttcttcca ttgtcaagta gtagttacct agaaccatat cttgagaagg agtaacaact
    19801 ggtttaccat ctttagggtt caagatgttt tgagcagcta acatcaacat acgtgcttct
    19861 gcttgtgctt cttcattcaa tggaacgtgg acagccattt ggtctccatc gaaatcggca
    19921 ttataagctt cacatacaag tggatgcaaa cggattgcgc gtccttgtac taaaactggt
    19981 tcgaatgctt ggataccaag tcggtgaagc gtaggtgccc ggttcagcaa tactgggtgt
    20041 tccttgatta cgtcttctaa aacatcccat acttcgtctt cttgacgttc gattttacgt
    20101 ttcgcatttt tgatgtttga agctagttcg cgttgaacaa gctcacgcat cacgaatggt
    20161 ttgaataatt caatggccat ttcttttgga agtccacatt ggtacatctt caagaaaggt
    20221 ccaacaacga taacggaacg acctgagtag tcgacacgtt tacctagcaa gttttgacgg
    20281 aaacgacctt gtttcccttt caacatatga gaaagagatt tcaatgggcg gttacctggt
    20341 ccagtaactg gacgtccgcg acgaccgtta tcgatcaatg catctactgc ttcttgcagc
    20401 atacgttttt cattttgaac gatgattcca ggtgcattca agtctaacaa acgtttcaaa
    20461 cggttattac ggttgattac acgacggtaa agatcattca agtcacttgt tgcaaaacgt
    20521 ccaccttcta attgaaccat tgggcgtaaa tctggtggaa taacagggat aacgtccata
    20581 accatccagc ttggttgatt tcctgaagcg cggaatgctt ctaaaatatc caaacggcgg
    20641 attgcacgtg tacgtttttg tccttgtgca gatttcaatt cttctttcaa ttcggctgct
    20701 tctgcatcta gatcaacatt atcaagtaat tgtttaatcg cttctgcacc catagcagct
    20761 tggaattctt gtccatattg ttcacgtttt tcgcgatatt cgcgttctgt caacaattgt
    20821 tttttctcta aattcgtatt tcctggttcg atgactacat atgaagcaaa ataaatgatt
    20881 tcttccaaag cgcgtgggct catgtctaat acaagaccca tacgtgaagg aatcccttta
    20941 aagtaccaga tatgtgaaac aggagctgct aattcaatat gtcccatgcg ttcacggcga
    21001 actttcgaac gagtaacttc cactccgcat cgatcacaaa cgattccttt ataacggata
    21061 cgtttgtatt ttccgcaggc acattcccag tcttttgtag gaccaaaaat ccgctcacag
    21121 aacaaccctt cgcgttcagg ttttaaggta cgatagttaa tcgtctcagg tttttttact
    21181 tcaccgtaag accagcttct gattttttcg ggagaagcca aacctatttg catactttcg
    21241 aatttattta catcgatcaa aaggggttcc ctccatttca tttaatggca aaccgcaaga
    21301 cggctgatct tcgaccgcct tgcagctcat agaccggatt agtctaaatt atcttctgcg
    21361 gtttcaaagt tttggatgac atcgtctttt tcatcttcca cttgttcagc agctttcttt
    21421 tctaattctt tggcagtttg ctgttcggca aattttgtca aagcatcaac agtgatcaaa
    21481 tcgtcgtctt catcgtccat gtcgcgaagt tcgatctctg tttcttcgat atccaagaca
    21541 cgcatgtcca gacctagtga ttgcaattct ttcaccaata cgcggaatga ttccggtaca
    21601 cctggttttg gaattggttc acccttgacg attgcttcgt atgttttcac acgtccgact
    21661 acgtcatctg atttgtatgt caagatttct tgtaaagtat aagccgcacc gtaagcttcc
    21721 agtgcccata cttccatttc accaaaacgt tgtccaccaa attgagcttt acctcccaat
    21781 ggttgttgtg taaccaatga gtaaggtccg attgaacgtg catgcaattt gtcatcgacc
    21841 atgtgagcaa gtttgatcat gtacatcaca ccgacagaca cacgtccatc aaatggttca
    21901 cctgtacgtc cgtcgtacag aacagttttc gcatcgctgg ccataccggc ttcacgaact
    21961 gtttcccata cgtcttcatc acttgcacca tcaaatactg gcgttgctac gtggatacct
    22021 aactgacgtg cagccatacc caagtgtaat tccaatactt gcccgatgtt catacgtgaa
    22081 ggcaccccta aaggattcag catgatatcg attggtgttc catcaggtag gaatggcata
    22141 tcttcttccg gcataatacg ggatacaacc cctttatttc cgtgacgacc ggccatttta
    22201 tccccttcat ggattttacg tttttgaacg atataaacac gaactaacat gtttacgcct
    22261 ggtgacaatt catctccagc ttcacgagta aagattttca catcgtgaac gataccgccg
    22321 ccgccatgtg gtacacgtaa tgatgtatcg cggacttcac gagctttttc gccaaagatc
    22381 gcatgcaata gacgttcttc tgcagataat tctgttaccc cttttggcgt gactttccct
    22441 acaagcaaat cgccatcttg gacttctgca ccaatacgga tgatacccat ttcgtctaaa
    22501 tcttttaatg cgtcttcccc gacattaggg atttcgcgtg tgatttcttc aggtcctaat
    22561 tttgtatcgc gggcttctga ttcatattct tcaatatgga tagaagtgta tacgtcatct
    22621 tttaccaaac gacggctcat gatgatcgca tcttcatagt tgtacccttc ccaagtcatg
    22681 aaaccaacta aaacgttttg gcctagagcc atttcgcctt gttccataga tggtccgtct
    22741 gccagagtat cccctttttc gactttctca cccaaatgaa cgattggacg ttggttgtag
    22801 cttgttccgg agtttgaacg acggaatttt gttacatcgt atttatctaa tgcaccgttg
    22861 tcgcggcgta cgcggatttc agaagcatca acgtattcaa cgacaccgtc atgtttacat
    22921 aacaaagcag ctcctgagtc atgcgctgat ttgtattcca taccagtacc aacccatggt
    22981 gcttgaggat tgatcaacgg cactgcttga cgctgcatgt tggcacccat caaggcacgg
    23041 ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac tacttgttta
    23101 ggtgatacgt ccatgtagtc tactttatca atagatactt ctaagttttc actttgagca
    23161 cgagccataa caacgtcttg agcaaatgtt ccatcttcat tcaatgggct gtttgcttgg
    23221 gctacgatgt aatggtcttc gatatcagct gtcaagtagt cgatttggtc agtaacacga
    23281 cctgtttcac ggtctacacg acgataaggt gtttcgataa atccgaattt atttactttc
    23341 gcataactgg acaaactatt gatcaacccg atgtttgggc cttcaggagt ttcgatcgga
    23401 cacatacggc catagtggga gtagtgaacg tcacgaactt cataaccggc gcggtcacga
    23461 gtcaatccgc caggtcctaa ggctgaaaga cgacgtttgt gtgtcaattc gccaagaggg
    23521 tttgtttgat ccatgaactg tgacaactga gaagaaccaa agaattcttt gatacttgcc
    23581 acaactggac ggatattgat caattgttga ggtgtcaatg tttcagtatc ttggatcgac
    23641 attctttcac gaaccacacg ttccatacgt gctagcccga tacggaattg gttttgtaaa
    23701 agttcaccga ctgaacggat acgacgattt cctaagtggt cgatatcatc gacattgccg
    23761 ataccttcca tcaagttcaa gaaatagctc attgaagcaa tgatgtcggc tggacgaacc
    23821 gtttttacag ctgcttctgg atagccgttt ccgatcacgt ttacttcacg ttcagggtct
    23881 cttggtgaaa atactttgat gacttggaca gtcattggat ctgtgaccac accgtcttct
    23941 gatggatagt aagtcactga atttaggcca ttatcaatga aaggagctag tgtttccatg
    24001 acttggtgag tcagaactgt tcctttttca acgatgatct cgcctgtttc tggatcaact
    24061 aatgtttcag ctaatgtcag attcaataga cgtgttttca aatctaattt tttgtttact
    24121 ttgtaacgac caacgtttgc taagtcgtaa cgttttggat cgaagaaacg agcattcagc
    24181 aagttacgtg agctgtctgc tgtttttggt tcgcctggac gcaaacgttc gtaaacgtct
    24241 ttcaaacctt cttctgttct tgagtcgctt gcgtttttat gcaagtcttt ttcgactgta
    24301 ttgcgtaatg tttcgctgtc gccgaagatt tcaaagatcg tatcatcgga accaaatcct
    24361 aacgcacgaa ctaatacggt taaaggaatc ttacgtgtac ggtcgatacg tacataagag
    24421 atgtcttttg catcagtttc catttctagc caagctccac ggttagggat aacagtagaa
    24481 ccgaatcctt cttttccgtt tttgtcgact tttccatgga aatagacacc tggtgaacgg
    24541 actaactgag aaacgattac tcgctctgcc ccgttgatga tgaatgttcc ttgttctgtc
    24601 attaatggga aatcaccgaa gaatacttct tgtgctttga tttcgccagt ctcgcggttt
    24661 gtcaaacgca atgttacatg taatggtgca gagtagtttg catcatgcgc acgagcttct
    24721 gctactgtat actttggttc tttcaattca taatctacaa attccaaaga tagattgcca
    24781 ttgaagtcat cgattggcaa aatgtcttca aacatttctc taagtccctc atctaagaac
    24841 cattggtaag agtctgtttg aatttcgatc aaatttggta attccaacac ttcactgatt
    24901 cttgcgaaac ttctacgttc gcgatgtttt ccgtatttta ctacgtgtcc agccaagctc
    24961 ttcacccctc taaaatgtca ttcaaaaaga ctacccgatc aattgttaca ataatatttc
    25021 aaatattatt tttaggtaac aacagacatt ttttgcggct tttaggcaaa aaaaaaccaa
    25081 aaatagaaca ttctcttgaa accttacttc gtgagcttct acttttgttt ccttatatta
    25141 aagccgaaac ggacaatatt tcgtttctgc cttttcttca tcagatagtt tttgcaactt
    25201 catatactac acttattttc tataaaagtc aacacttcct ggcgtttctt ctgctttttc
    25261 gcaacatttt cttaatgttt tcaattttat gttttcaatt atctgacaat tcttaattga
    25321 cagacctttt tatctcggtt atactttaga aaattcattt tgtggaggaa cttctatgcg
    25381 aaccaacatc aaccaaatcg caccaacaca actgaataac ttttacttta gctactttag
    25441 ataggtttgt attcatcatg atggatacaa acgttaaacg acagtttgta tctatgatgg
    25501 ctaaagaact ttgtattgca gcaaaaagcc acgtagacaa aatgctaagt ggctgagcag
    25561 tgaaaataca aagtaaaagt atcaagcatt ctactttttc aatttatttt ccgacttttc
    25621 aatccatttg gacattttgt ctgaatggat tttttgtttc ccaaaattaa ggaggaaaaa
    25681 gaaatgaaaa aaaatataat catcggatta ggcgctgccc tgctactagc tttaggaggt
    25741 tgcgcacaaa aagacaattc cgcagaggca tcagatggac aaaaaacaat tggcgtattg
    25801 caacttgtac aacataactc gttagatgct gcctataaag gattcaaaga aggattagca
    25861 gaagaagggt ataaagaagg cgataatcta acaatcgatt atcaaaatgc ccaaaacaat
    25921 caagacaacc tgaaaagtat gagtgagaaa ctcgtcaaag aagatcctga tttgctactt
    25981 ggaatcgcca ctccagcagc acaatcttta ttaaatgaaa caaccactat cccgatgact
    26041 gtcacagcgg tcacagactt ggaacaagcc catttagtca catccaatga aaaacctggc
    26101 ggcaatgtga ctggcacgac agatatggtg ccaatcgaaa aacaaatcgg cttactgtta
    26161 aatatcgtgc cagacgccaa aacaatcggc atcatgtata acaacggtga agcaaactct
    26221 aagatccaag ctgatttggc agaaaaagaa ttgaaaaaag cgggcgtcaa agtcaaagta
    26281 ctgacagcaa attccacaaa tgatgtccaa caagtgacga aaagtctagc taaagatgta
    26341 gatggaatct atattcctac tgataacacg ttcgcaagtg cggcaagtgt tgtcggtgaa
    26401 gtcgcaaaag aaacaaaaac acctgtcgtt gctggcgcag ttgatcaagt caaagacggc
    26461 ggtctagcaa cagtaggaat cgactacgaa agcttgggca aacaaacagg gatcatggca
    26521 gcaaaaatct tagacggcaa gaatccaagt gaacttcctg tcgaaacagc gaatgatttg
    26581 gaactgtatg tcaataaaga catggccaaa gcattaggca tcaatccaga cagcatcaaa
    26641 gaagctgaat aaaacacagg aggattctca tgacaaattt gctctctctt ttcttatcat
    26701 ctgcatcgca aggggtctta tgggccctac ttgcgattgg tgtatacgtc actttccgta
    26761 tcttggacat tgccgacttg actgctgaag gaagctttcc tttaggtgca gggatcgcgg
    26821 cagtaagtat tacaaatggc tatcatccat tgacagcttg tcttctaggc tttttagggg
    26881 gtgcggcagc agggcttgtt tccggactgc ttcacacaaa attgaaaatt cccgcccttc
    26941 ttgcagggat catcaccatg actggtttat attctgtcac atcccgtgtg atgggtgcgc
    27001 cgaacatctc tttattgggt cagccaacga tctttcattg ggtcgagtca ttcggcataa
    27061 caaaagacaa cgctgtactg atcgtcggtc tgctttttgc tttgatcgtt gtatgtttac
    27121 ttgttttgtt cttacgtaca gaaacaggac ttgctattcg tgcaactggc gataatctgg
    27181 caatgagcga agcaaacggg atcaacacag ataatatgaa gatcatcggt tatatgattt
    27241 ctaatggatg cattgctctt tctggctcct tacttgcgca aaacaacggc tttgctgatt
    27301 taaattctgg tattggaacg atcgtaattg gacttgcttc tattatcatc gcagaagttt
    27361 tgttacgtaa ccagccacta tttctccgtc tcttgactgt cgttttaggt gcggtcattt
    27421 atcgttttat tttagcgtta gtcttcgaac tgaatgttga accaagtgat tcgaaacttg
    27481 cttctgcttt cgtgctagtg atctgtcttt ctttcccgca gatccagcaa aaattccatt
    27541 tacctcaaaa aaagaaaggc ggtagtgtca aatgaatgac gtcttaacat tggaaaatct
    27601 ccatcatacc tttgaaaaag gaacgatcaa cgaaaatcat gtcctgaaag gcattaatct
    27661 ttccttagat cccggcgact tcgtgacgat catcggtgga aatggggctg gtaaatctac
    27721 tttgctgaac agcatcgccg gtacattttc tgtcgatcag ggtcaaattt tattgaatgg
    27781 aaaaaatatc acgaaaaaat ctgttgtcga acgttcgaaa tccatcagtc gcgtattcca
    27841 agatcctaaa ctagggacag ccgttcgttt aacggtagaa gaaaatcttg ctcttgctat
    27901 gaaacgagga aaaaaacgcg gcttcttccg tggtgtcaaa ccacaagacc gaacattttt
    27961 caaagaccag ctggttcggc taaatttggg gttggaaaat cgtttatcct cagaaatcgg
    28021 tttgctgtct ggaggacaac gtcaagctat tacgttattg atggccacat tacagcgtcc
    28081 agaactgatc ttattagatg aacacactgc agcgcttgac cctgctactt ccaaaacggt
    28141 gatggaattg acagaaaagc tgatcactga gcagaatctc actgctttta tggtcactca
    28201 tgacatggaa gacgcgatcc gctatgggag tcgactgatc atgctgcatc aaggaaggat
    28261 cgtcgtagat atccagcaag aggaaaaaca gcagctcaca gtgccccaat tattagcgtt
    28321 gttcaaacaa aacagcggca cggcattaaa agacgatcaa gtacttttat cttcataatc
    28381 agaaagagga tgggacaaaa aatgaacgcc caccctcttc ttttttctct ttccttcttt
    28441 cgtttttgct ttatgtatca accgttgttt cttcgaaaac tattttgttc tctccttctt
    28501 cctgatagaa tggatgggaa aggagcttga tgccatgaca acgaaagaca aggtacttca
    28561 attattgaaa aagacaccag attttctttc cggagaaaag ttggcacagc aactggaagt
    28621 ttcccggaca agtatttgga aagccatcaa agaattggaa aaggcaggct atcgttttga
    28681 gcacgggcct acagggtatc gttacctgcc ctctgacgta ctagatgcaa aagaaatcca
    28741 gcaagagcta cggtcgttta ttcctgattt gaaagtacaa acgatgttga cttctgaatc
    28801 tacgatgaaa gatgccaaac tggcagcagc tcaaggagat tctgtttcga agttatttgt
    28861 tgctgataca caagaacaag ctcgtggacg ttttggacgg ccttttttcg ctgaacctgg
    28921 acgaggaatc tacatgagtc tcttgctcca tccagacaaa cggtttgatg aattgcctca
    28981 atatacgatc atcgcagcca gtgcctgtgt gaaagccatt gaatctgtaa ccggtcgttc
    29041 tgcttcgatc aaatgggtca atgatatcta catggatgga aaaaaagtct gtgggatttt
    29101 atctgaagca gtcagtgata tggaaagcgg caggatcagt catatcatca ttgggatcgg
    29161 gcttaatttt tctgttcctc aaaatcattt tccagctgat ctccaagaaa aagccatctc
    29221 tgtctttccc gacggacaag ctagtgtcac aaggaatcag ctaatcagca aaatctggca
    29281 agaattgttc acttatcttt ctcacccaga aaaagcgttg gacttctata aagaaaaatc
    29341 attcgtattg ggaaaaaccg tgtcgttcaa tcaaaaagga acgacttatg tcggtcttgc
    29401 aaaagaaatc ggtgatcatg gcgaactgat cgtccaaaca aatgaacaga agatgagttt
    29461 gtcttctggc gaaatcagtc tcacatctat ccgtacgcaa taattatcag atttcacaaa
    29521 aggacacctg atctcataca gtgtcctttt ttctgaattc tcttcaaaag actctcctta
    29581 ttctatcagc tgacagtttc tctatcctct agaaaaaggt attctaaaaa tatctataaa
    29641 gcatggtaca ctttctttaa atgaatcaat gcaaaaaaca agagagtcat cagtttacac
    29701 gatcaaaaga gatagcaggc cgcttccttt ttcaatctta tagatagacc atgggtaacg
    29761 ataaaaacaa aaaagaactt gcgacttatt ttgccgtaag ttctttttta gctagtgcct
    29821 taatctctta atcccaacaa acgtctcgca tagatcacct gaccagagtg catagcagca
    29881 tcatcaataa tagaaacgag acgcattcct cgtgtgactg gtggtgtcca gttctcgtca
    29941 attacttcat ctagctcgga aggttccagc cttcttaagt aagaaatagc aaaatcagca
    30001 gctcctcgca agtatcctag cagatcttct atttgattag cttggatctg ctttgcttgt
    30061 tccagactat gcttccaatc ttgttcgtta tctgctatcg tcatcggaaa ccggctttcc
    30121 cagtcttgac tatgccaaat tggagaagtt cctgctaaat cagcaatctg gaaatctaat
    30181 tctcgagcgg tatgccaagc cagccaagtc attgatttga tctgcggggc tctatcttcc
    30241 actggaaaac gattggcctc ctcaatagag acgccttcaa acaaacgttc aaaccgatcg
    30301 tatgcccgat ccacactctc gcatagcata tctaaataat ccatttattt tcctcctttt
    30361 tatttatcct acttactttt tcctaattct aggataccta cttatatgtt actacacacc
    30421 cttatttttt acactttaac agtcaccatc atcaatagtt tggagattga aagaaaaaga
    30481 tagtgtcgaa ctatcaattg aacaagaagc aacaatatga acgtttcatt aatattcttt
    30541 aaataaacaa tgatttttca aacgaacagt ttaagactag gagaaaaaga gtataatagg
    30601 aaaatgtttg aaaggaaagg aaggggaaaa atgaaaaaaa gggcaagttt actagtccta
    30661 gttgctttgt tgttcaatat cttttcgtat ggtgtggccg tttcagcgga aacatacatt
    30721 cctaaagacc ctgggaatat ttataatgat ctaactggta actatggctt gttaggaatt
    30781 gctagtcaat tccacgtatt tgctaaaaat aagacaactg tgaatgcaca tacagacgga
    30841 aatatagcaa cacatgaact tgatgcaaaa aataattttg gtacagagct tcatgaaggt
    30901 ttattgaacc aagaaataaa ttatatacaa aaaactgatt ctttcgctaa ttcttcaggc
    30961 atacctacag gtagcacaag aatgaataaa tttgtcgttg gcagtaacgt ggatgtagca
    31021 cttcaagatg gtcatcctac agtcaatgga tccaggcttg atcacttaac tccagatgat
    31081 ttttataaag atcgtgctgg gcatgaatat attgatttcg agcaggaatt tgctaaattg
    31141 aatgtagcag caaatgatct tgcaacgatc actccagcta aaacatatac tgctgcagat
    31201 tttccagaca tgaacaatcg gacaatcgat ttaactgatt tatcagatac cgggttttta
    31261 ttggtaaata tcgatgcaga agtgttaacg atgaatacgc cacttcaaat cattaatcca
    31321 aatgatcaag tagttgtatt taatgtcatc aacagttctt ctgcattgaa cgtacagtca
    31381 ccaatcaaat acaatgatcg ttcaaatcat gaaacagaag atttttcgga tgcgaatatc
    31441 tcttggaatt ttggaaatga gatgactgat ttgacaatca gtgctccttt tcaaggaaca
    31501 atccttgcgc ctaatgctac tatccgcatt actcaaaacc aagacggaac gattatagga
    31561 acaaatgtga ttttagatgc agctaccaat cgttgggatc ctaacgaaat atttatcagc
    31621 gacaatggta cagatacgac agacacaagc gacagtacag atacatctac cacaagtgat
    31681 agctcagatt catcaacttc aagcgacagt acagatacta cctctaccac
//
LOCUS       DAIGQM010000031        31451 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.031, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000031 DAIGQM010000000
VERSION     DAIGQM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.031"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            225..668
                     /gene="rplM"
                     /locus_tag="NOA48_001402"
     CDS             225..668
                     /gene="rplM"
                     /locus_tag="NOA48_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCI0789671.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            684..1076
                     /gene="rpsI"
                     /locus_tag="NOA48_001403"
     CDS             684..1076
                     /gene="rpsI"
                     /locus_tag="NOA48_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0789672.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(1165..2391)
                     /locus_tag="NOA48_001404"
     CDS             complement(1165..2391)
                     /locus_tag="NOA48_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789673.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2463..2621)
                     /locus_tag="NOA48_001405"
     CDS             complement(2463..2621)
                     /locus_tag="NOA48_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789674.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            3309..4049
                     /locus_tag="NOA48_001406"
     CDS             3309..4049
                     /locus_tag="NOA48_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0789675.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            complement(4141..5328)
                     /locus_tag="NOA48_001407"
     CDS             complement(4141..5328)
                     /locus_tag="NOA48_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0789676.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            5650..6492
                     /locus_tag="NOA48_001408"
     CDS             5650..6492
                     /locus_tag="NOA48_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0789677.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            6492..7439
                     /locus_tag="NOA48_001409"
     CDS             6492..7439
                     /locus_tag="NOA48_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0789678.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            7454..7687
                     /locus_tag="NOA48_001410"
     CDS             7454..7687
                     /locus_tag="NOA48_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HCI0789679.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            8018..8602
                     /locus_tag="NOA48_001411"
     CDS             8018..8602
                     /locus_tag="NOA48_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0789680.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            8733..9401
                     /locus_tag="NOA48_001412"
     CDS             8733..9401
                     /locus_tag="NOA48_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0789681.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            9412..10827
                     /locus_tag="NOA48_001413"
     CDS             9412..10827
                     /locus_tag="NOA48_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0789682.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            10845..11414
                     /locus_tag="NOA48_001414"
     CDS             10845..11414
                     /locus_tag="NOA48_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HCI0789683.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            11524..13278
                     /locus_tag="NOA48_001415"
     CDS             11524..13278
                     /locus_tag="NOA48_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789684.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            13238..15004
                     /locus_tag="NOA48_001416"
     CDS             13238..15004
                     /locus_tag="NOA48_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789685.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            15527..15796
                     /gene="rpsN"
                     /locus_tag="NOA48_001417"
     CDS             15527..15796
                     /gene="rpsN"
                     /locus_tag="NOA48_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0789686.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            15811..15990
                     /gene="rpmF"
                     /locus_tag="NOA48_001418"
     CDS             15811..15990
                     /gene="rpmF"
                     /locus_tag="NOA48_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0789687.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            16022..16399
                     /locus_tag="NOA48_001419"
     CDS             16022..16399
                     /locus_tag="NOA48_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789688.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            16420..16569
                     /gene="rpmG"
                     /locus_tag="NOA48_001420"
     CDS             16420..16569
                     /gene="rpmG"
                     /locus_tag="NOA48_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0789689.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            16593..17576
                     /locus_tag="NOA48_001421"
     CDS             16593..17576
                     /locus_tag="NOA48_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0789690.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            17606..17728
                     /locus_tag="NOA48_001422"
     CDS             17606..17728
                     /locus_tag="NOA48_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0789691.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            17746..19269
                     /locus_tag="NOA48_001423"
     CDS             17746..19269
                     /locus_tag="NOA48_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0789692.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            19293..19532
                     /locus_tag="NOA48_001424"
     CDS             19293..19532
                     /locus_tag="NOA48_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789693.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(19725..20186)
                     /locus_tag="NOA48_001425"
     CDS             complement(19725..20186)
                     /locus_tag="NOA48_001425"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0789694.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(20381..20599)
                     /locus_tag="NOA48_001426"
     CDS             complement(20381..20599)
                     /locus_tag="NOA48_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789695.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            20717..22333
                     /locus_tag="NOA48_001427"
     CDS             20717..22333
                     /locus_tag="NOA48_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0789696.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(22574..23914)
                     /locus_tag="NOA48_001428"
                     /pseudo
     CDS             complement(22574..23914)
                     /locus_tag="NOA48_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(24190..24345)
                     /locus_tag="NOA48_001429"
     CDS             complement(24190..24345)
                     /locus_tag="NOA48_001429"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCI0789697.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(24641..24973)
                     /locus_tag="NOA48_001430"
     CDS             complement(24641..24973)
                     /locus_tag="NOA48_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0789698.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(25487..25678)
                     /locus_tag="NOA48_001431"
     CDS             complement(25487..25678)
                     /locus_tag="NOA48_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789699.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(25772..26158)
                     /locus_tag="NOA48_001432"
     CDS             complement(25772..26158)
                     /locus_tag="NOA48_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0789700.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            26852..28057
                     /locus_tag="NOA48_001433"
     CDS             26852..28057
                     /locus_tag="NOA48_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HCI0789701.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            28074..28508
                     /locus_tag="NOA48_001434"
     CDS             28074..28508
                     /locus_tag="NOA48_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789702.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            29125..>31451
                     /gene="esp"
                     /locus_tag="NOA48_001435"
     CDS             29125..>31451
                     /gene="esp"
                     /locus_tag="NOA48_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HCI0789703.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMEDDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT        10724 a         4669 c         5825 g        10233 t
ORIGIN      
        1 ttgtcacagc ctctttttgt ttttcatttt gacaggaaac gaccctttta tataaaagaa
       61 agaaaagaag taaagtttca tataaatttt tcaatcaagc agaaaaacgt tgacattgac
      121 tagattagcg ggtaatatgt taaatggtat tgtttgcccc acaaagagcc ccggaaactc
      181 gaagtgtatg tcaaacatca gaacttaaat tggaggaaaa taacgtgcgt acaacatata
      241 tggccaaacc aggcgaagta gaacgtaaat ggtatgtagt agacgcaact gatgttccat
      301 tgggacgtct ttcaacagtt gttgcatctg tactacgtgg taaaaataaa ccaactttca
      361 cacctcattt ggatactggc gatttcgtca tcgtcatcaa tgcagacaaa gtgaaattaa
      421 caggtaaaaa agcgactgac aaaatttatt accgtcacag caactaccca ggaggattga
      481 aatcaatcac tgctggcgaa ttgcgtgcta aaaattctcg tcgtttgatc gaaacttctg
      541 taaaaggtat gcttcctaaa aacactttag gccgcaaaca atttacaaaa ttgaacgtat
      601 acggtggagc agaacatcca catgcagcac aacaaccaga agttttagac atcacaaact
      661 taatctaata ggagggaatt tcattggcac aagttcaata tatcggcaca ggccgtcgta
      721 aaaacgcagt tgctcgcgta cgtctagtac caggaactgg caaaattact gtaaataaaa
      781 aagatgttga agaatacatt ccacatgctg acttgcgtga agtaatcaat caacctttcg
      841 ctgttactga aacaaaaggc gcatatgacg tatttgttaa cgtaaacggc ggaggatacg
      901 ctggacaatc aggagctatc cgtcatggta tcgctcgtgc attgctagaa gttgatcctg
      961 acttccgttt agctcttaaa cgtgctggct tacttactcg tgacgcacgt atggtcgaac
     1021 gtaaaaaacc aggtctcaaa aaggctcgta aagcatctca attctctaaa cgttaatatt
     1081 atttatatat caatgtttca aggcactttt caattgtttg aaaagtgtct ttttcttgtt
     1141 taagaacaca tttaagaaca catactaatc acatttattc aatcctctct gaaaggcttc
     1201 aaaaacagtt ttatctacta catctggtgt atttacgtat attctcgttg tagaaatatc
     1261 tgagtgtgtt aaagcactag atatttgatt catatttgct ccgccttgtc tagctatagt
     1321 tgcataggta tgacgaagct tatgtggaga taaatgagcc aattcaggat gtcgtctttt
     1381 aattgaattg attcgatagt ttaggtaatc agcgtgaaca gggcaattta cttctccgga
     1441 tggtttagta taggtaaaga gatactgatc tggtgtttga ttaattttta atctcaacaa
     1501 ttgctcagct tgcactgatt tccatttgct tagtaatgcc attacaattt cgggtacttg
     1561 aattacggta tcctttcgac cttttgtaaa tttctttttt tgatatttat ccaaagcatg
     1621 tttaaggcga accgtttgtt tctcaaagtc gatatatttc cattgcaaag catacgtctc
     1681 actttttcta tcaccaagat atagggtaag catgaaaaga gtatagtcat gaagagtaag
     1741 caagtgatta ttcaagtcag tgtttactgc ttctatccaa gcaataagct cttctgacga
     1801 taatgcttga ttaccttccc gtatccttct ttcttctaaa gcaatttttt taggtgcagt
     1861 gatacattga ataattttgg tagttcggtt aaattcaata taatttagta tttctgcaat
     1921 atcaaacata gaacggacat atcctttgat aatttttata tttgcgtatt ctttcgattt
     1981 ttttgttaat tcatctgata ttatctcagt atttgaattt agatagttca ttgcatactc
     2041 accaaacatt ggaaggatgt gcaatcggaa tatatcttta gtattactaa ttgttacgta
     2101 acttggagct ctttttgatc tagtagtctg acctagttca tatctaggaa gccattttga
     2161 ttcatagaat tccttaaatt ttatttttcc ttttaattct agtgaatttg cattctcctc
     2221 tcttaaaact gtttcaattt tccttttcat tgcattttcg gctttaatag ccaattgcct
     2281 agttggaaat actttttgat acttttctga tgtaattcca gtgatttctc tgaatttttt
     2341 tggatacctc agattagttt tatatttccc atttgaaagt tttgtaggca aaattcctca
     2401 ctcccttaaa aagtaaggca gtatatttcg ctattcttag tatatgcggc gagaagaaat
     2461 tttcaaattg ttttaaatgt attcataaaa tctttgatat cctctatgtc aaagcgaact
     2521 ataccgtcaa ttctgattac tggaaaatta tatatacgaa tccacttatc taaagtatta
     2581 ttatcaattc ctagaaactc acaggtttgt tttttattca agtagactct caattttata
     2641 aaatcatctc ctaaaaaaga ttagaatttt tgaattgctt tgggtaagca cataggaatt
     2701 tcacctctcc ccagtttacg gcgagcctta cggaagtatc attatttgct gctattgtca
     2761 tggcattttg ttttcccaga acaaaaagaa atctctaagt atttgtcgct aatcaggtca
     2821 tggcgtactt gagtttctag ctcgaatagc agggatcgtt attcaaaaat tgtatttaat
     2881 tgtcaatgat caaaaatagg ttttttccta ttcactatta ataacgataa acatgtataa
     2941 aaagacacac tacgaaaaaa gttaaatgga gtttactgat tttcatattt gtatatggaa
     3001 cagacatagt cttgaataat ttttataaat gttttgatgc ttatcaactt attcaacccg
     3061 ctatccactt taagtataat ttttccatac gccaataaag tagttttagg agcatgttct
     3121 catttgagaa cgctcctttt ttatatattt tgaaagctac ttactatacg cgtagtttca
     3181 aatagttttg tcattctaat cttcagcaac agaaaaaaat ctaaattata aaatttaggg
     3241 ttgactaaaa tataattttt gtataccata tgatcgtgat aatcattatc atttagaagg
     3301 agaaagttat gttagaagtg aaaaagctta atgtttgtta taacgatttt ttagcattga
     3361 acgagatttc tttaaaaata caagaaggtg ctttaacagg tattattggt ccaaatggtg
     3421 ctggaaaatc tacattgctt aaagcaatgt taaatattat ccctcatcag ggagaggtct
     3481 ccattaataa tgaagatatc aataaaaaac tggtgaagat tgcatatgta gagcaaaaag
     3541 ctgatattga ttttactttt ccaataaaag taaaagaatg tgtatctatg ggaacatatg
     3601 ccggaatgaa agtttttcaa agaattaaaa atgcagaatg gcaaagagtt tcaaaggctt
     3661 tggaaaaggt cgatatggga aaatattcta atcatcaaat aggagaatta tctggaggac
     3721 aatttcaacg tgtactttta gcaagatgtc ttgctcaaaa tgcggatttc atatttttag
     3781 atgaaccatt tgtagggata gacttagtta gtgaacgaat aattatggat acgttaaaag
     3841 aattgaaaca tcagggaaaa acagtgctaa ttgtgcatca tgatttaagc aaggtaaaga
     3901 agtattttga taatattatt cttttgaatc gaaatctaat tgctcacgga agtgtagaat
     3961 ctgtatttaa tgaagagaat ttaaaaaaag cctatggaga tactatattt attggagaga
     4021 ctaactatat agagtcaagt aaaaattagc caaatcaaaa aatattttat aacagataat
     4081 tccgaaaaaa gggtacaaca aataagcttc ttaccattag tttttttgaa tgttcaatag
     4141 ctaatcagaa acaattatat aaggctcgtt tttagtcaaa atagcatgaa tcacgtaaca
     4201 aagcttacga gaaaccgcac ctaaggcagt tagatgatgt tttccttcgg aaactttttt
     4261 ctggtaaaac gcactaaaaa caggatcaca ttgagaagct actaaagccg ccgaaaacaa
     4321 ggcttttcgc aaatatggag accctcgttt actcataaca ttatgcgttg cctcatattg
     4381 ccctgattgt gtcacggaag cgtctatccc agcgtaagca acgagttttt tcgggttaga
     4441 aaatttttga atatctccga tctcaccaag aatagtcgca ccgtttatag gaccaattcc
     4501 aggaattgtg agaataacag aatttaaagt gtccattatg tgcttgattt ctctttccgt
     4561 ttcctttatt tggctttcaa tgaattttaa ttgttcaatc attgaacgta gttggaaggt
     4621 gaacgcttct tgagcaaatt ttactccaaa ggagttagaa gctgcttgct tcaattggtc
     4681 cgctttttct gccttgattc ggttcctgct taactcagct aagtattggg ccaaagtttc
     4741 tgaggaaatg ttttctaagt cgatcggggc actaaacgcc agcaataact ctttagaagc
     4801 ttttccgaaa acgccctgct tggtaaaaat cgtcgcgtat tctggaaaga cttgatccaa
     4861 tacggctata atttttcttt tgaagtcgct cgctgtacct actaaataag ttcggtaacg
     4921 agaaagttgt ttcaaagaaa aaacattttc atcggataag accgtttcga caaatgagcc
     4981 atagcgcatt aagtcagcaa tcaaaacaga atcaataata tcgttttttc gtttccgtat
     5041 ttctgtacct ttacgccatc cgtctgtttg aaggggattc acaacgtgaa tcaaataatc
     5101 tgattcgtga aggtatgaaa agatggacag ccaatagtgc cccgtggctt ccatccctat
     5161 aacaaagtca ctgggtgctc cggaatagtc gaccattcgc tcaattaatg actctgctcc
     5221 ttcagtggtg ttaggaaatg aaaaaccttt tagtaatacc tttccttcct cgttcatgat
     5281 agaagcaacg tgagtgcgtt taccgatatc aatgcctaaa aagtacatgt atatctgacc
     5341 tttcaaaaaa agaattttgg attgaaatcc actcaactga aaagcgtcac taccttgtac
     5401 gagatacgga gtaaagtaag gactttcaac atctaactca tacgcaatcc acttatcaga
     5461 gagaggagcc agtctctcga gtgcgggttc aatggcccaa ggggggaacg gcttagcctc
     5521 tcaatccaat aaatatatta tctcaaaaga aatgagttaa taccaaatta aaataacgat
     5581 ggttcatagg gttatccaat caaaaccgga aggttaaaac cctaactcta atatacaagg
     5641 gggaataata tgcttcaaaa ttttattaat ggtctgtatg actttcactt tttacagaat
     5701 gctctaatta catctgtagt tatagggatt gtttctggaa cagtaggttg ttttattatt
     5761 ttaagaggaa tgtctcttat gggtgatgct atttctcatg ctgttttgcc aggagtagca
     5821 atttcttata ttttaggtat taattttttt attggtgcga ttgtatttgg tctattagct
     5881 tctatcatta ttacttttat aaaaagcaat agtgtaataa aaggagatac agcaattggt
     5941 attactttca gttctttttt agcattagga gttatcctta taggagttgc aaatagctca
     6001 acggatttat ttcatatctt atttggaaat attttagctg tacaagatat tgataagtgg
     6061 attacaattg gcgtttctgt tttagtgttg gttacagttg ttctattttt taaagaatta
     6121 ttaatcactt cttttgatcc attaatggca aaagcaatgg ggatgaatgt cagtttttat
     6181 cattatctat taatgattct attaacttta gtagcagtaa cagctatgca aagtgtggga
     6241 actatattaa ttgttgcaat gttaattaca ccagctgcta cagcatattt atatgcaaac
     6301 agcttaaaaa ctatgatatt tatttcggcg acagtcggag cgtgctcatc attgctaggt
     6361 ttgttcattg gttatagttt taacatagca gcaggatcaa gtattgtttt aacagcggca
     6421 ttcttatttg taattagttt tctaatctca ccaaaacaaa aatttttaag aaagaaggag
     6481 agaaagttat gatgagaaaa tggaaagcag tactgggaag tctggggatt ttgattgctc
     6541 tttttatatt cggggcatgt tcaacaaata gtaaagacaa agatacagtg gcttcgaacg
     6601 aaaaattaaa ggtagtagtt actaattcga ttttagcaga tattactgaa aatatagcaa
     6661 aagataaaat tgatttacac agtatcgtac ctattgggaa agatccccac gaatatgaac
     6721 ctttgcctga agatgttcaa aaaacttcaa aagcagattt gattttttat aacggtgtta
     6781 acttggaaac tggaggaaat gcttggttta caaaattagt aaaaaatgcg aacaaagagg
     6841 aaaacaaaga ctattttgca gcaagtgatg gcatagatgt tatttactta gagggtcaga
     6901 gtgagaaagg gaaggaagat ccccatgctt ggttaaattt agaaaacggt attatttacg
     6961 ctaaaaatat tgaaaaacag ttagcggaaa aagatcctga taataaaaaa ttctataaag
     7021 aaaatctaga taagtatatt gaaaaattgg attctctaga caaagaagct aaatctaaat
     7081 ttgcttcaat tccgaatgat aaaaaaatga ttgttacaag tgaaggatgc tttaaatatt
     7141 tctcgaaagc gtataatgtg ccttctgctt acatttggga aatcaacact gaagaagaag
     7201 gaacaccaga tcaaataaaa cacttagttg aaaaattacg cacaacaaaa gttccctcct
     7261 tattcgtaga aagcagtgtg gacgatagac caatgaaaac agtatcaaaa gataccaata
     7321 ttcctatcta ttcaacgatt tttactgatt caattgcaga aaaaggacaa gatggtgata
     7381 gttactatgc gatgatgaaa tggaacctgg ataaaattgc tgaaggcctt tcgaaataat
     7441 ttggagggta ggtatggtac aaattaaaac gactactata ctaatttatt tactagcaat
     7501 tcaggaatta tcaaaaagaa aaaagaaatt aaaaaataat gatttagcaa aagttctaag
     7561 tgttagtcca gcatctgtaa gtgagatgct ggctaaactt agatatgagg actatttaga
     7621 tataggattt caattaactg ataaagggaa aaaatttatt gacgattaca aaaaaggttt
     7681 taagtaaaag actttatttt tagggaggat aagaaaatgg ctattggagt gattatgata
     7741 ggacttaccc taatagctgg atataatttt tttaaatctt tctcggatta ttttagaaaa
     7801 ggtgaatgat ttagatgagt ctattaattc ttgtaggatt gctttttgta tcagttattt
     7861 tgctctttct cattagttta gctctaagga atgagttcag taatagacgt taacgattga
     7921 aacttcaagt cctgtgtaag ataatatagt taattcatct tattaggagg aagtacccat
     7981 agaaaccaga gattatatta caactcacca aaaattaata gaaagtggac taagccattt
     8041 tgaaaaagaa ggatttcagc aaactaagat aaggcaactg tgcttgaccg caggcgtaac
     8101 tacgggtgct ttttataaac attttacttc taaggaagcg ttatttgaag aaattattca
     8161 gccgcatatt aatgcgctta ttaatatgta taatgaagag tttaccaaat acctcttaaa
     8221 cttagaaaat atagatatag agaaaagttg gagagagaac ttcaatgaat tagatccatt
     8281 tattaattat atttttgaga ataaacgtat attcgatttg gttttattcc aatcagctgg
     8341 aaccaaatat caagatattg ttgaaaaaat tacatcattt gtgacaaaaa agacagtctg
     8401 ttgtctagat aagttaaaga ctatcggaat gatcaatcaa aatttagtct ttaatgaaga
     8461 agaaatccac ttctacattt actcattcta cgctacattc tatgatatat tgaagcatag
     8521 ctattcaaaa gaaaagacta tgctattaac cagaagattg tatcaatttt ctgttcctgg
     8581 gtggattgaa ttactgagtt aattaaaaaa aagcttgcat tgagaattgt tctcagttat
     8641 gctttttgat aagatcgcac tgttatctga ataacggtgc atttttgtca gcttaagata
     8701 acagtgcgat cttatttttt ggaggtgaaa gagtgtcaaa aatcaatccg ttaaccttga
     8761 ttactttaaa tatttttttt ccggtcatta tttttttagg aaagggaaat atatttcaag
     8821 tggggtgttt cattattgct acagttttag tattgatgtt tcgtaaaata aagacatgta
     8881 tttatttcat cttgatttat tcagttctgt ttttagtaat gaaaattatt gatgctatca
     8941 agatagagtt ttttactata ttttttggga catccttata tattgtattt cgaatgttgc
     9001 cggtcgtaat gatctcatgg ttgttggtta gtgtctatac tagcaatgaa ttattatcct
     9061 ctttagaaaa aatacattta ccgaaaaaaa taatgttaag tattacagta gtgatcagat
     9121 tctttccgac ttatcgttct gaaataagaa tgattaaaga atctttaaaa atgagaaaca
     9181 ttcgcttgtc tttttttcag cctctgcaat atttggaatt tctgttagtt cccgttctta
     9241 tacgtgcaac tatgattgct gaagaaatga ccgctaatgc aataacaaag gggatagaat
     9301 ctcctgtgaa aagaagttct tactataaaa caaacatgag cttattagac tatatcatcc
     9361 tgttttccgt tactattttt ttcttaagta ttttgatttg aggtgaaaga attgtttgaa
     9421 tttaacaatg tttctttttc atataaggat gttaaggaac aagcgcttgt tgaccttaat
     9481 ttttcaataa aaaaaggcag tcttacattg attactggtt cttctgggag tgggaaatcc
     9541 acactattaa agttaatgaa tggacttatt ccaagacttt atgacggaaa attggttggg
     9601 gaaattttat ttgaaaataa ctcgctacaa tccttaacac aagaaagtat atcaaaaaat
     9661 attggctacg taagtcaaaa tcctagagga caattcttta caacaaatac aacgagtgag
     9721 ttagtatttt cgatggaaaa ctttggattt acaaaagagc atatggataa aagaatcaat
     9781 gaattagctg aattattaga tctttcaaat atattagata aaaacatttt ttcgctatca
     9841 agtggtgaac ggcagaaaat ttctattgga tgtagtttat cgctaaactc taaattaatt
     9901 atattggatg aaccgtcttc aaatttggac ttcaaagcga ctaagaaact tgctgactta
     9961 ctttgtgatt taaaaaataa aggatttact attgttatag ctgaacatcg tttttactat
    10021 ttgaaagaat taattgatca agttctattt gttaaaaata gaactgtaaa aactacaact
    10081 attcagttgt taaaaactga aaacaataac gcattaagga aatttgacat ttttaatagt
    10141 tcgattgaag ttccctatat cgaaaaggta agtgcagatg tattaaaagt tgaagaaatt
    10201 acttatgaaa atattctaaa agacataaat tttgatgtca aagttggaga tgttattggt
    10261 ttggtaggga aaaacggtgt ggggaaaaca accttactaa gaatactcat gaagattatt
    10321 cgccctacca aaggaaagat aatcgaaaat aaaaaaaatt tgtcatcgcc gtttttagta
    10381 atgcaagaaa tggattacca atttttcaca gaatcagtga ggagcgagtt agccctgggg
    10441 aatgaaatag ttagtaaaga tcagcaagaa aaaattttaa aaaaaatgga actttataaa
    10501 atgaaagatc aattaccgtt tgatttatcc ggtggagaaa aacaaagatt attggtttct
    10561 atagcttcat tgtcaaaaac taatttattt ctatttgatg aacctacaag tgggttggat
    10621 tatatcaata tggaaaggat tgctgacctt attaaagact taaaagaaaa gggtgcagta
    10681 gttatagcca ctcatgatcc ggaatttctt tataaaacat gcaatagaat tatttattta
    10741 aaaaatggtg gaataaaaaa agatataaaa cttagagtag aagattcaac tttgatagaa
    10801 cagattttta atgacataac gaaatagaat tgaggagaat atatatgaaa acaaaagatt
    10861 atatttttat tggtttagct acagttattt ccctagtaat ttactttttt tcaataatgg
    10921 ttagtagtat tggtggggcg tttggtcaca gcatatcccc agggattttt ggattattat
    10981 ctggaatcat atttgtttat attagctata actaccctag aaaaggaatt tttactattt
    11041 acacaattgt tttattgtta ttttttacgt taatgggcgg ggcgtactta ccttggttta
    11101 tcagttcgat tagtatggcg atcttagctg atattattct atctgtattt ggatatgatc
    11161 gagcaattcc tcaagttgtg tcttgggttc taatgcaact aggcagtgct gccggacagt
    11221 ggattcccat atggttcttt acagatcgtt ttcgtcaaga ctggatagat agaggacaat
    11281 ctgctgcaac aatggatgca atgatccact acgcggtggg tatatgggga attatttcag
    11341 tgttagttgt agcaagttta tctatgattg gtgtattgat tggaagaaaa gtcttaaaaa
    11401 aatacaaaaa atagaacgta gtttaccttc tatctgtttg tacatctcta atttacgcta
    11461 ttacggaaag cattaacagt tgtaaacgaa taagagaaga aattgaatgc gggggaggaa
    11521 aaaatgaaag tatacaaaaa attatttagt tatgtcccta aaatgaaata ctacggatgg
    11581 ttagccactt tattttctga tttttctgtc gtattaacag tctatggata ttacagtatt
    11641 tacaaatttc ttcagtctct aattattgta ggagatgaat atttagctaa gagttatgcg
    11701 gttcaaactg ttgcttggtt aactttagga gctttatttt atattttttc tggcttattt
    11761 tctcatatcc ttgggtttcg cttagagact aatttgagaa aaaagggaat tagcggttta
    11821 acagaagcaa gttttcgttt ttttgattta aattcttcgg gatatattcg aaagacaatt
    11881 gatgacaacg cggctaaaac acatatggca attgctcact tgattccaga tagtgctcaa
    11941 gccatagtaa cacctgtttt atcagttgcc ttaggctttt tcattaactt taaaattgga
    12001 ttggttctaa tcgccatgtt agtaattggt gtattcttgt taaagaaaat gacagagaat
    12061 acaaatttta ttcaaaaata tcaagaatcg ttagatgtgt taagctctga aacggtagaa
    12121 tatatccgcg gaattcaagt tataaagata tttggtgcta aagtaacatc atttaaagcc
    12181 ttgaataaag caattaacga ttatgctaag tttgcatata agtattcttt gagtgggaaa
    12241 acaccttttg ttctttttca atggctattt tttggcatag tttgcatttt gatagttcct
    12301 ataacctttt ttataacttc tcttaccact cccaagatct tagctgttga cttgttgatg
    12361 ttgttttttt taagtggaat tatttttgtt tctttcatga gaataatgta tgtaagtatg
    12421 cacttgtttg aagcaagata tgcagtcgaa acactagact ccctttattt agaaatgaag
    12481 caagaccaac taaaatatgg gaacgagaca cagattaaaa attgtgacat tgcatttgaa
    12541 aatgtcagct tttcatacaa agaagagtgt gttttagaaa atttcaactt agttttagaa
    12601 caaaaaagaa tttatgcatt agtaggaaaa tcaggaagcg gaaagagtac gatagctaaa
    12661 ctaatttcag gtttctacaa tgtggataag ggacagatta aaattggtgg taagccttta
    12721 aatcactatt caaaagacac aattattaac acaattgctt ttgtctttca agatacgaaa
    12781 ctattcaatc agagtattta cgataacgtt tctatagcaa atcctcaagc gccagcaagt
    12841 aaagtatttg acgcgctaag attagccggt tgcgaatcga ttttagaaaa atttcccgaa
    12901 agagagcata ccttaattgg tagtaaagga gtttatctgt caggaggaga aaaacaacgt
    12961 atagctattg ccagagcaat tttaaaagat gcaaagattg ttattatgga tgaagccagt
    13021 gcatctattg atccagataa tgagtatgaa ctacaaaagg cttttcaata tttgatgaaa
    13081 gaaaaaacag ttattatgat agctcatcga ttatccagca ttaaatctgt agatgaaatt
    13141 cttgtcttgt cagaaggaaa aatagtagaa cgtggaaatc ataatgaatt aatggctaaa
    13201 catcgagtgt ataaacaatt ggtcactaat tatgagaatg caaatgattg gaggcttgac
    13261 aatgaaaaat ttttataaaa aaaaatttgc tttaactgat cagggcgcag aagctttaac
    13321 taaagcttct atttctagtt tttttgtata ctgcattaat atggtaccag cattcattat
    13381 aatgatgctg atagacgaat tagttttaga aaatgcaaag ccccgttggc tttattttgc
    13441 agtatcgttt gttactttgc ttttcatgta ttggttgtta gatagggagt atgaaaactt
    13501 atataatagt acttataaag aaagtgcgca tttaagagtg caaattgcag acgatttgtc
    13561 aaatttacca ttatcctatt tttcaaaaca taatttatca gatttatctc aaactatcat
    13621 gtctgacgtt gaaggtattg agcatgcgat gagtcatgca atacctaaag ccggcggtat
    13681 ggctctgttt ttccctttta tttcagtgat gcttttggtt ggtaatgtca aaatgggatt
    13741 agctgttatt ttgccaacgt tatttagttt tgtcttaatc ttgttatcaa agaaatccca
    13801 aacgaaagcc aatactaaat attacgatac tttgagagaa aactcggaag aatttcaaga
    13861 aactattgaa ttgcagcaag agattaatag ctttaatcta tctaaaaaag ttcaagacag
    13921 acttttcaaa aaaatggaag agagtgaaag gattcattta aaggtagaat taagtacttt
    13981 ttcagtcatg gccttatcct ctattttctc atatgttagt ttagcagtag tcattctagt
    14041 aggtgttcac ttactgttaa cgggtgaagt gactatactc tacgtcgttg gttacttact
    14101 agccgcaata aaaataaagg attccttcga ttctatgaaa gaagcagtgc ttgaaatatt
    14161 ttatttagct cctaaaatac agcgaattag agctatgaag gaaaccagta tccaagaggg
    14221 atcagatagt cctctgaaat cttttgacat tgagttgcga gatgtctctt tctcatatga
    14281 taacaatacc ccaattttag atcatatctc ttttacggct aaacaaggag aagtgactgc
    14341 gttagtaggt gctagtggtt ccgggaaaac tagtatcttg aaattagtgt ctagactgta
    14401 tgattatgat gaaggctgta ttttaattga tgggtatgat attaaacgtg tatctccagc
    14461 ttctttgttt agcaaaatcg ctattgtttt tcaagaggta actttgttta atacaagtat
    14521 tttggaaaat atacgtattg gaaatagtca agcgtcagat gaggaagtga aaaaagcagc
    14581 tcgtttagct aactgcgaag actttattga aaaactacct gacggttatc atacattggt
    14641 cggagaaaac ggaagttcac tttctggagg agagcgacaa cgcctatcca tagcacgggc
    14701 ttttttgaaa aatgcgccaa ttttaatttt agatgaaatt actgccagtt tagatgcgga
    14761 aaatgaaaaa cgtattcagg aaagtttaaa tcgtttaata caagataaga cagtactaat
    14821 tatatcgcat cgcttgaagt ctattgaaaa ggtaaataaa attgtagtga tggatcaagg
    14881 aaaactagtt gatcaaggta ctcataatga gttgtatcga aggtcagaaa tatacaaaaa
    14941 tctcataaag aaaactaaac tatctgagaa attcgtctat gaaaaagaag ctcaatcacg
    15001 atgatgaaat aggctttaaa ttaacctaca atttttggga tatagttata attctttttc
    15061 aaaaagaata attttattaa acagcatcta attttgaata cacgaaagaa tcagtatgat
    15121 tgaattagtt cacttaatgt ctattcttat aatataagga ataatcaaag ttttaaaaaa
    15181 ttggcgataa accagttaaa cataaaagat tgaataaaaa gttatagttt ctttcatatt
    15241 gccgttttaa gtagaggaaa agctacttaa aacggtattt gtgtttgatt ggactaataa
    15301 aagtgaattc ttatttttca gagcctaaac tgcatattct tttaaatgat ttgattatct
    15361 ctatgtaccg ataaattcgt tttcaaatag ttatctattc atatgagttt tatttcatgt
    15421 tatttattgt tgacaagagc aactcttgtt ggtaaagtat cagtgtcaaa acgtaacgat
    15481 tacgatttga ggtgtctaaa tcaaaataaa aggagtataa aggtatatgg caaaaaagtc
    15541 gaaaattgct aaagcaaaga aacaaatggc gatgattgaa aagtatgcag ataaacgtca
    15601 ggaattaaaa gccgcaggag atcgcaccgc tctcgctaaa ttgccaagag attcaaatcc
    15661 gaatcgtctg aggcttcgtg atcagacgga tggtcgtcca agagggtata tgcgaaagtt
    15721 cggtatgtcc cgtattaagt ttagagaact tgcccatcaa gggttgattc ctggagtaaa
    15781 aaaagcaagt tggtaaaagg aggaaatatc atggcagtac cagcaagaaa aacatctaag
    15841 gcgaagaaac ggttaagaag aactcatcaa actgtagtaa aaccagaaat ttcatttgac
    15901 gaagcgaatg gtgattatag acgtagccat catgtatctt taaaagggta ctataatgga
    15961 aagaaagtaa ttaaaggagc ttcaaaatag tttaatatat aacttttagg agggaatcaa
    16021 aatggaaatt atttacccac ctttagttga agaaggatta aagtattatc ttgaaacgac
    16081 ccagcaatcg ctagataaat gcacttttta tcgttcgatg gtagagagag gaattattac
    16141 tgaaacgggt ttaccgaccc aacaggcaat tgaaaatgga ttagtcaaag attactatga
    16201 ggaccaaggc ttatcatttg atgatttttt aagaatctat ccaatttttg aagagtatga
    16261 cgaggagtta tttcaatgta tcgatggtta ttgggagata cctgttgata tgaaagaaaa
    16321 tttagtttca caattggaat ctggcgagtt aacttttgaa gatgcacaac aaattcaagc
    16381 atatcttgaa gatcgataag tattgaagga ggaagattta tgcgtcaaaa tattattttg
    16441 gaatgtgtcg aaactggaga acgtctgtat ctcaccagca aaaataaacg gaataaccct
    16501 gaacggttag aattaaaaaa gtattcgcca aaattgcgca gacgggcaat ttttaaagaa
    16561 gtgaaatagc taagtggtaa aaaggtgaca aaatgggcat accagttaca atcgtttctg
    16621 ggtttttagg ggctggaaaa acaacgctaa tcaatcaagc cttgcaagtc tcaccctacc
    16681 ccagggaaga aattattata attgaaaatg agtttggtga agttgggatt gatcacaaat
    16741 tattagttca tagcgaggaa cgggtgttac aactaaataa tggatgtatg tgttgcagtc
    16801 ttcgcagtga tttattagca atattgattt ctttactgga aacaatagaa gaacatcaac
    16861 aaccaatttc acaaatcatc attgaaacta caggtatagc agatccccaa ccaatcattc
    16921 aaacactttt aacagcgcct caactaagag gaagagtata tatcgatagt ttattgactg
    16981 ttattgatag tgacagtttt gaacttattg aaagagaacc acaagccctt aagcaacttg
    17041 tcatggcaga tcgcattttt gtgtctagaa aacaaaactt gaatttatct gcactaaaaa
    17101 aattacagag agaaatcaaa agtattaacc ctttatccga tattcgaatg ttcacacata
    17161 gtgaaacgat tcaaaaaaag gatttttata atttgaaaaa atttaatcat cccttagttt
    17221 ttgaaagtga ttcatcagaa aatcactata atggcaaata ctatcatcaa caccatcaag
    17281 tacatgagtt taaatcaatt ctcttaactt cagatcaaga cataaaaaaa gattttttac
    17341 tccaatggat tgactggctg attttaacca accaagggag cctgtatcgt tttaaaggat
    17401 tgattgcttt acaagagcag gattttatag ttgccatgca agaggtaaac gaacaggtta
    17461 attttcaata caccactcga caaaaagacc aaaccactat tattctaatc ggaaaaatgt
    17521 tggatgaaga aaggatcaaa cagagttttg ataaattact ggcggaaagc aaataatgat
    17581 aagtagtgat tgggggtaat ttctaatgga gaaaacggat atatctagtg catatcgacg
    17641 acttaaaagc ccgaatatta aaactagaaa aagggcatta aaaattatca aagaacataa
    17701 acgaaataaa atgaagaaat tagcataatt aaggaaggaa aaagaatgaa gaaaatcagt
    17761 gtaggactta ttgggatagc agctctagga ttattgggag cttgctccag cactaatgat
    17821 gcaaaagtat cgaatgataa agatggaaaa ttagaaattg taacaacatt ctatccaatg
    17881 tatgatttca ccaaaaacat cgtcggcgat gaagcgaacg tggatttaat ggttccagcg
    17941 ggatcagaac ctcatgacta tgagccctca gctaaggata tggcaaaagc tcatgatgct
    18001 gatgtttttg tatatcataa cgaaaacatg gaatcatggg taccaaaagc taaagaaagt
    18061 tggaagaaag ctgggcctaa tgtagtagaa ggaacaaaag acatgatttt attgccaggt
    18121 agtgaagaag aagatcatga tcacggagaa gaagatcacc atcatgaact agatcctcat
    18181 acgtgggttt cacccaaaat ggcaattaag gaagtttcaa atatcaagga tcagttagtt
    18241 aaattgtatc cgaaaaaagc aaaagtattt gagacaaatg ctgaaaagta tttgactaaa
    18301 ctgaaacggt tggatgctga ctataccact agtcttaaag aagcgaaaca aaaaagtttt
    18361 gtgacgcaac acgcagcctt tggatattta gctttggatt atggattgaa acaagttcct
    18421 attgctggac taagtcctga agaagagcca tcttctggtc gattagctga attaaaagag
    18481 tatgttaaaa aaaataagat caattatatt tactttgaaa agaatgctaa tgataaaatt
    18541 gcaaaaactt tggccaacga agctgggata aaattggaag tactgaatcc tcttgaaagt
    18601 cttacaaaag aacaaatgga taatggtgaa gattatgttt cagtaatgga agacaatcta
    18661 aaagcgttag aaaaaacaac tatggttgct ggtgaagagg tagttccaga aaaagaagcg
    18721 aaggatgaaa agacagttgc taatgggtac tttaaagatg ccgatgtgaa ggatcgcgaa
    18781 ttgagtgatt atacaggcga atggcaatct gtttatccgt tgttaaaaga tggaattttg
    18841 gatgaagttt tcgattacaa agcaaaaatc aataaagaca tgacagctgc cgagtacaaa
    18901 gattattata ctactggcta taagacagat attgatacta tcaacattaa agacaacacc
    18961 attgattttg tagtcaacgg tgaacatcat caatacacat acaaatatgt tggatacaaa
    19021 attttgaatt atgaaaaagg aaaccgtggt gttcgtttta attttgaaac tgatgatgca
    19081 ggtgctggtc gttttaaata tattcaattt agtgatcatg gaattgcacc aagtaaggca
    19141 gagcatttcc atattttctt tggtggagaa agtcaagaaa aactctataa tgaattgcat
    19201 aattggccta ctttctatcc agcttcattg tctaaacatg aaattgctca agaaatgatg
    19261 gctcattaaa attcaatttt tggaggaaat acatggtaag aaaagtatta ttgtctatgg
    19321 attccaagaa tattgatgct tatcggcgtt atcgatttgc aaagcaaatg agattaaatg
    19381 ggagtacatt agctgatatt gctgcaactt tacatgttag tattgacaca gttcatagag
    19441 tattaaaacg ggatcctgat tgttgtttta tcaaggtcaa tactggaaga agtagacgtt
    19501 tagcaaaacg gcataatagc ttggccaatt aattgataat accagagtag atcatttttc
    19561 ccttatttgg atttgatctg ctttttatta tgtcttgaat tgtcaaatca agcgcaacac
    19621 tttatcaaag aagacttcat aaggtgttct ccaatctaaa cactttctag gtctgttatt
    19681 cagtttttca atcatctgat ttatcgttga gttatctacc gtagctatct ctttcgattt
    19741 tggcaagtat tctcgaatga gtctattcgt attttaattt gttcattgtt gccaagggca
    19801 tgaggatctg gaaaataaaa gggcatatta ttcaatgctt ctgtaactgc gaaatgattg
    19861 gagaattctt ttcctctatc tggagtgatc gttttgaccg cctcatttgg aatactgctt
    19921 aaaagttcaa tcattttctc gctcacataa gcggctttct ttctggggac cttctttcct
    19981 gctaaaagga agcatgattt tctgtctgtc aaagtcacta aacaagtacc accagttttg
    20041 ccagctacaa tatcggcttt ccaatgacca aaatcacttc tatcatctgc ggattttgga
    20101 cggccatgga tcgaatgagt aaggcaaatc tttccacgag actcgacatg attttttgta
    20161 tgtcttgttt ttcctcgatg gtgcaatgaa cggatcaggc ctttattgcc gtgtgagagg
    20221 ggttctgtat cgaaaagatc attgcaaatt gcacgttaga tcgtgataaa actaattgaa
    20281 aagtccatat gttcatgctt caaacgattc gagatttcct ctggcgacca ctgaaaatcg
    20341 acaaataaat gacgaacaat tgaccaaact cacggatcat ttagaatgtg ataacgtccg
    20401 catttttttc ttcgataagc ataatttttt tccgctttgg aaggtgaata gtttttttct
    20461 tgtttcttct cagttcatgt aaaatagtaa acgggctatg ctgaatgtcg ttgccaatta
    20521 tactaataga aaatccttct tcgtgaagca gaaagattct ttctcgttcg agtatagtaa
    20581 gatgacgata ctggctcata attattttcc ttctaggagt gttctcgaca aacttatact
    20641 agttggatat cgattatgac tcatttttat gtgttgcact taaagtgtaa attcaaggta
    20701 tagaaagagg ttccctatga aaaaaatacc tattacaatc ttaactggct atcttggttc
    20761 aggaaaaacg atacttctaa atcatattct gtacggtgat cacggaaagg aaattgctgt
    20821 cattgtaaat gacatagggg aagtaaatgt tgatggggta ttagtcgaca agaaaggttt
    20881 taaaagaact ggagaaaaac ttgtttcgat gccgaatgga tgcatttgtt gtacattacg
    20941 cgaagatttg attgttgaac tagatcaatt agtgcaattt tctgacttga atcaaattgt
    21001 tattgaagct tcaggaatca gcaaaccaat tccaattatt caagcaatta tattagctaa
    21061 aaacccttta gacattgatt tgacccaacg attagagatt ggtgccatta ttatagtagt
    21121 ggatgtaaaa cgtttttggg ataatttcga aacgggtgaa aagattcagg aaagaaaagc
    21181 tgaaggtaat gtagttgaag aagaacagga tattcgtggc ttgttaattg atcaattcga
    21241 gtgttgtaac atattacttt taaataatag tgacttagtg tcaaccaaga cgatttacaa
    21301 aattaacggt ctaattgcta agttacagtc caatgccaaa ataattagga caattaaagg
    21361 tgaagtagac ttatcgaaaa ttctaaatac aaatcttttt aatatagatg agacttccta
    21421 ttcagtgggc tggttcaaag agttagagct tggctatcaa aatcatattc ctgaaacaga
    21481 agaatatggt atctcaagtt ttatctatcg aaatcggtta ctccttgacg cacaaaaatt
    21541 tgcccatctt acggataaaa attttcctgg caatattaca agagcaaaag ggtttctttg
    21601 gtttgcccaa catagtgatt tttcgacgat ctttgaaaca tcgggtagct ataaaagtat
    21661 tgaatcatta aattattggg tagctagttt acctaaaatt gagtgtcaaa tgattataca
    21721 aaaaaatccc gaattgaagg aagcctggca tccgttgttt ggtgaacgca ttaataaact
    21781 agtttttatt ggtatgaaga tggatcaaca atgtattaag gaacaacttg agggttgttt
    21841 aactgattct cttaatgcag ataatttccg aaaaatttca ccatttccat ggaaaaagtc
    21901 taatatgttt agccagatat cgttaatgaa atttttaaga aaagctggtg tcaagatagg
    21961 cgatgtcata attattggca ttttgattat tacctctttt attcccttat ttgtattctc
    22021 tatagaaaag gagaatgaaa caactgaaga tgctatcaaa tatgccatcg ttcgaattga
    22081 tggcaaggaa atggatcgct tcgatttgga taagatcaat cataaactcg tgaattatca
    22141 tcctgcgaag ggacaatata atattgttga gattaaagat ggaagaattc gagttaaaga
    22201 agataatagt cctgatcaaa tcgcggttag aactggatgg atctcaaaac ccggtcaaac
    22261 gagtatttgt ttaccccata agttagttat tagtattgag aaaaaagaaa gcacagatta
    22321 ctacatttac taatctggaa atagatgagg aggtttttaa taagaaaaag atattattat
    22381 taataatagc aggggcttta ttaagtgtgt taagcgcttg tggacaagaa aaagaagcgg
    22441 tgacaacagg cacaagtatc tttaacggga cctgcaatgg tttagttaac agtcggttag
    22501 attacttatt ttggctcttc gtcaatgagt gttggtgaag aaattcaata gaataatcga
    22561 gatactcaca cggctagaca gctatcttgt ctagccgtgt tgttgttctg gctttagtca
    22621 gttgggtagt attcttagtt ttcttaaaat attttcctcg atataaaaag attcgttctc
    22681 ggtagttttg aaagtttcta tagccatagg caattcgttt tagtactttg atatggttat
    22741 tcaaacattc tatagggccg ttggaatagg gaacgcgcaa cgctcgtttg atttctgttt
    22801 ggtatttctt gaaggtcgtg aacactggtt ggtagtgctc tggcaactcc ttgtagtctt
    22861 cttttaggag cgcgacgaat tcaggaacat cttgtcttct gataacggaa agaaaatcct
    22921 ggtagacttc gtagcctcgc tttaaggaat catcataaga taatagccga tcgactatct
    22981 ctgcttctgt cagatgatct cgaaatgacg gacgccagta gcgatgctga cctttcaatt
    23041 cccacgcatt cttttgaagt agtttccagt atttctttaa gtgcttcgac cgacgatccc
    23101 cttttttaaa ggtcttcatt acttgaattc ggtggttggt aaaagcccga ccaatgtgtt
    23161 ggctaatatg aaagcgatcg gcgacgattc gggcattcgg aaaacactct ttcaccaatg
    23221 tgcgataggg tgtatagaaa tctgaaacca ctagacgcac ttgttcacgg acttttatag
    23281 ggtagcgcaa gaaatagtcg cgtaaaggat tgagttgccg attttccaca atatcaatca
    23341 gttgatgggt cttgccgtcc atcatgacaa agctcatggc tcccgagaca tttttcactg
    23401 atttgaattc atcgaaacac accacttctg gtaacagctg gctcaaagaa atggttttag
    23461 gccgaaggct gcgaagtatt cgaatgacag tggtcggaga aatgtgcttc atacgtgcga
    23521 tcaaagacat agaaagaggt tcgcttaata gctcaagaat ggcttgtttg actctgcgag
    23581 caatggagca gcgacgatca ctaactgaat cttctgctaa aaaagtcttt ccacagtgtt
    23641 tacatttgaa gcgctgtttg ttaatccgca gaatggtctt gtagttactg acatcattca
    23701 ataagatgga tacttttttc cagccctatt taatgatcgt ttgttcattt tgatagtggc
    23761 gatgaaagca ttcctccggt tgataggtca atgtgccatc aaaaacaaaa catgtttcgt
    23821 cattgattcg ctctttgcga aaggcatctt catgaaagat aagatttagg tctagaatat
    23881 ctagtaactc tttggtaaac tctgaatagg acatcttgaa acactccttt gaatggtttt
    23941 cgtcgacttt attctaaagg attttaaggt gtctgtttgc gtttattaga aaaaagaaaa
    24001 agtattggca acagaaggcg tcaccaacac tagatattat agatccctta ttttcttcgc
    24061 ttcaaattgt caaggagtca tcataaattt tgtatggatt cttttgtttg ggtagtagtc
    24121 ttctaaataa tcttggatta acaccttcat ctctatttta cttttatatt tgttggagtc
    24181 gattaattct catttgattg atcgatgaaa cgcttcaatt actgcattgt caacaggagt
    24241 cccagtttgg ctcactgaat gtgtgatgtg gtggtcgttc aacagctctt gataaataaa
    24301 agaccgatgc tggctacctc tatcggaatg aattaccgta ggcaattctc cttaataaat
    24361 ttgtaatgga cggacgacaa tctctttttt catgtgtgaa tctaccatat agtaacgtag
    24421 aatacgagtt gctaagtcaa tataggtgga caaatagagg cgaccgtcat tacatggaat
    24481 gtaagtaata tccatcaccc aaacagcatc aatttggttc tgttcaaatt atcgattcaa
    24541 cattttttta ccatttcttt gattgttttt tctctaccat gagaagattt gcgtcgatga
    24601 aatcctcttg tgcataaatt catttcacgc ataagaacag ctacaacacg tttattgatt
    24661 tcgattcctt catcgtaaag tttttgagtg atccctggag atccgtatcg atctttgtgt
    24721 tcgtagaaca ctcgtcttcc tcttttagtc gtttattttc ctgttcaaga atgtagaaat
    24781 ctgctttatc aggtaatctt tttccttgtc cagcaaaagc atttttcccg tatcgacgat
    24841 attctgaaac ccatcgggaa attgttggac gagagatatt gtattcttca gcaattttct
    24901 tggtagttac ttttttctca aggatatcct gtgaaatctt tagtttaaat ttacgatcat
    24961 atgtttttct caatagagtt cattccttcc ggtaacgtaa ctgatagtca agaaaagtgt
    25021 atcatagccc aacttagtat cagggtttgt caactaaact gtggaagttg atagataaga
    25081 gtttttaaca accaaaattc tcttgactat ttttgaaatc agacaaattt tgattggaca
    25141 catagttgaa taaatctacc gtcgttacgg aaggtaaatc gcatgctttt caattctaga
    25201 ggagaagtcc tcgttgaagt accatagccc agttctggat tcgacctcct gcccacttca
    25261 tacgtaaata aagtaatttt aggagtgaga ctgtgacaaa agttattttt aagctaaaaa
    25321 cgaattaaaa aacgttgata attaaaatca ttcgttttag attctatgaa tcattataga
    25381 acgctgtaaa atcgatactt tataattata aagaagatag tttcaaattt attgttcgaa
    25441 atttgaaact atctttttac ttatgtcaca gactccctta gttgagttat tctttaattt
    25501 cgaatttcga gatagctaga tatattgcaa gcatacattc ttgataacaa tcttgatcat
    25561 attttccagt tctccaggat tgcttatgaa tcaaagagct aaatcttttg agaattgcct
    25621 caacagcttc ttcatttcca gcctttgcta aaatgaaatc ttcttttaaa gaattcataa
    25681 atctaccttc ttcccatgga cttataatct atttctttgg gaaggaggag aacgagcaaa
    25741 gaagcataca aaattagtta ttatgcagat attaaaccag cattttttga atttttttgt
    25801 aaagtcgatg ttttaaattt gtcgcaccct gtcttgtaat ccccagaacc tttccaattt
    25861 ctttatcagt tttatcaaag ataaattttt cgataagaaa aatttgttca ggttctttca
    25921 acaaaggaag gatttttgct aattttatat cttcaacaag gagagtcaca tttaaaacat
    25981 taatcggttg tttaaatttt atagtatctt tagtaaacaa atatggtggg agttgatcaa
    26041 gttgttcatg tttttgaatt tcttcttgtt ttttataata agtattagcg gtgttcaaaa
    26101 tgaccttttc aaagaatcga atcaactggg catttacgcg ttcgtcgtta tctgacatat
    26161 tgcacacctc ctccattaag atttaaaggg aaaagaggca aaaaacacga aaagaagcta
    26221 atgcaattat gctgcgctgc gaataacttc tataagctca catgcattga taggactgct
    26281 gatgtttatt ttcaaaaatg tttttttagt tgataatgga tagttatctt tatacttaga
    26341 aaagaaaatt catatatctt cttaaatatc aaacatgtcc ttatggctaa gaaaatgtct
    26401 tgagcttttt acgtataata aatcttttct aaaacctcct tttggataat attcttattc
    26461 gtgtatagat tgtatttttt atttcttccc ccttcataat taacaactag aaaagagttc
    26521 gaatagacac gtatttgaac gaaaattttt attggattcc caaattggaa tatttagaaa
    26581 cgaaaaattc ctattatctg tatagtgctt agataataac ggatcataat aattattgtc
    26641 tttgaactag atatatgtaa atagtattca tcatgatgaa aaatgatgag ttctcggtga
    26701 taaaatgtac tttttacggt ggaatataca tgaaagcgat aagtggatat tttataatga
    26761 agtaagttag cttattttga cagaggaata gtattttaga taacgtataa aatactattt
    26821 aatgatgtag aaaggaaaga gagaaacaaa agtgttttca gataaagaag tcttattaaa
    26881 gtctcttcat gtttgtttaa agttacctat cgtggttttt aattccgaat tcagtattat
    26941 aaaagagtat cgctcagata gaactactta ttttttttat gattataaaa agttactaac
    27001 tgataatatt aaaaaaacta aagatttcca tttctttact ggtgatttta atgagatgtt
    27061 tcttctatac atgtttaaaa ccagatatta cttatttggt ccatttagag caaataatat
    27121 tgataaagtt ttttttaaac taaaaatgaa caatttgaat gttgcaatgg ctgatagaga
    27181 acgactctat aattcattgc aaaatttgac tttgtattct ttaggagaca ttcgagatat
    27241 tctgatttta gttcattatt tttttactgg aaaaatagaa gatctattcc atgaaccgtt
    27301 aattgaatat acagaaaatc taagtaaaac tatcgagcaa atcaaaatag ataatctgtt
    27361 atcacaaaat tacgatccag aaatatatct gtttctttat gaaaataaaa tactggaata
    27421 tgttaaaaat ggagatattc gaaatttaga aaacatggtt tttaatctga gtaatggaat
    27481 aattccaagt gttagtggag atacgattcg gtctgaaaaa aattattcta tcattgtttt
    27541 tgaaaagtta gcacaaacgt ctataacatt aggaatggat ataatagaag cgtatcaaag
    27601 tagagatgct ttgatacaag aaaacgaatt agctgtatcg ttacctgagg tcttaaaagt
    27661 gagggattct gggattgttt attatactaa ggaaatcgga aaaactaaga tagagcatct
    27721 ttctccctta atttcttctg tcgttcaatt catcggctta aatatctata aaagaattac
    27781 tgtaaaggaa atagctaatt atttttctgt aagtgaaact aaattaagag aaagctttaa
    27841 gaatgaaatg catattacga tttataatta tatctctaag cgaaaaattt ctacggctaa
    27901 aataatgttg aaatcaaacc atactatcag tgaagtttct ttaggtttag gattttcaga
    27961 ttcttcacac ttttcgagag tattcaaaaa gtacgcaggt gtatctccta agcaatatca
    28021 attaggttta gtggacaatt tcaacaacat tagctgagag gttttatttt attatgagac
    28081 tatatcattt acgtagtttg gaggagttga ggaaattgga ttttaacaaa aaattttttt
    28141 gggaaatttc tgatttgagt tgtttcgtag aatctgagcg tctaagtaat ggtaataata
    28201 gtgtgttaaa tgaatatgac aaagtagtaa ttaataaagt aaaaagttta tgtgaagaag
    28261 ctagagaatc tatcagtcat attaatggta gcaattttaa acaaacatta tttaatctga
    28321 ttaagctaga tgctaaaata tcaagttatt tattcttttt gatacatgat gaatttatgg
    28381 attatcaaaa attggatcag ttaattgaaa gagaaagctg ggaagattat tacgtgggtc
    28441 taactttttc agaaaagtta aacaactaca agttaataga ttataagtat ttgagtgaaa
    28501 gcaattaatt attcatgtag agtactagac actttaaata tggacaattc aattataaag
    28561 aaaaagaatc aataatttaa tgaggctgtg acaaatgtca ttttttgttt cgctaaaaac
    28621 gagtgaaaaa atgttgataa ctccaatcat tcgtttaaga ttctaggaat cattcagaaa
    28681 tgctgtgaaa ccgatacttt ataattataa agaaggtgat ttcaaattcc gaagaaggaa
    28741 tttgaagtca cctttttact tatgtcacag tctcattcag taatgcggga taaggctcct
    28801 tattccgtta tttgaatact ctgaagttta atctaagaaa gggtaatatt ttgaaaacat
    28861 gcttcatcgc atagaaatga acttaatttc agaaagaata catacatatc tttttatatg
    28921 ttttcagctg ctgaatggtt aaaaagcaca aatatccgaa aaaaacatga agaaatgtac
    28981 tttttttgtt gtaatgttca tgaaattctc taagtaaatt agttaacata aggttagtaa
    29041 gattcctatt ctgtgaataa tacgtatcag atttatcttt tattcttact aggaaagtaa
    29101 ttattaaggg agttgatttg aataatggtt agcaagaata ataagagagt atttctagaa
    29161 aaaacaaaga aacgagtatt gaagtacagt atcaaaaaat taagtgttgg ggttgcatct
    29221 gttttgattg gtgttggtct tgtcttggga acaactgaac tagttaaagc acaagatgaa
    29281 atttctccaa gcagcccact tgaaacagcg ataagctccg tacaagtagg tgacaaagta
    29341 gcttcgggga atacttttca ggagaatcct ggttatacga aaaattataa cttttcggat
    29401 ttacaattta gtcctcaaga actaactgga gacacactaa aaggcaatac aattggattt
    29461 gaagtttacg gaaaacataa tattgcagca tcaactaaaa actgggaaat ccgtcttcaa
    29521 ttagatgaac gattagctaa atatgtagaa aaaattcagg tcgatccaaa gaaaggaatt
    29581 ggatcttcta gacggacctt tgtaagaatt aatgattcgc tgggtagacc tacaaatatt
    29641 tggaaggtca attatattcg tgcaagtgat ggattatttg ctggggcaga aacaaccgat
    29701 acgcaaaccg ctcctaatgg ggtaattacg tttgaaaaga gcctagatga aatttttaaa
    29761 gagataggca tagacaatct caagaccgat cgtttaatgt atcgaatcta cttggtaagt
    29821 catcaagacg atgataaaat tgtaccgggt attgatagta cgggctactt tttaacagat
    29881 tcagatgatt tctataatag cttagatgta tctgaaaata atcctgacca gtttaaacat
    29941 ggatcagtaa gtgcaaaata tgagaaacct aatactcaaa caaaagatgg ttcaggatcc
    30001 acaggtgcta atggagctat aatcttagat cataagttaa cgaaaaatta taatttctca
    30061 tattcatctt ccgcaaaggg cacgccttgg tatgctaatt acaaaattga tgaacgatta
    30121 gttccatatg tagcgggtat acagatgcac atggttcagg ctgacaaagt aacatatgat
    30181 gtttcgtttg aatccggaac aaaagtagct gatttagcaa tcgagcgacg ggaaggtcat
    30241 gaaaattatg gcataggttc aataactaat aatgatttaa ctaaacttat cgattttgct
    30301 aatgcaagtc cacgtccagt cgttattcga tatgttttac aattgactaa gccattagat
    30361 gaaatcttag aagatatgaa agcaacagca caagttgaag aaaataaacc atttggtgaa
    30421 gatttcatct ttgattcttg gttgtcggat acgaataaaa aattaatcca gaacacttat
    30481 ggaacaggtt attattattt gcaagatatt gatggtgatg gaaaccctga cgataaagaa
    30541 gagagcggag acacgaatcc atatatcggg aaacctgaat tagaagaagt atatgatgtt
    30601 gacacaacag ttaaggggaa agtattcatc cacgagttag cgggaacagg tcacaaagcc
    30661 caacttgttg ataaagaagg tactgtatta gcagaaaaaa ctatcgctcc aaatgaaaaa
    30721 gatggggctc caatttcaga tactgtagaa tttgaattta cgggtgtaga ttcaagtaaa
    30781 ttaatcgcga aagatgaatt aaaaatccaa atcgtttctc caggttttga taaaccagaa
    30841 gaaggttcaa ccgttattaa ggaatcacca aaagcggttg ataaacaaac cgtggtagtt
    30901 ggatttaaac cagatgctaa agaatcaatt cggaataata aaaacttacc tgaagatgca
    30961 gagtattcat ggaaaacaga gcctgatact tctaacgtta ctgatagtac gaaaggtatt
    31021 gtaactgtta agatcggaaa tcgaactttc gacgtggatg tagagtttgc tgtaaaagct
    31081 tctcaagcta tggaagatga tgcaacatac gtacctataa caacaactcc agaaacgaca
    31141 gttcaaagtg gaaaacctac atttgataaa ccagatgttc ctttagctaa agatgccttt
    31201 tcaatttcag atgtctataa taaggacttc ggtaatgcaa gtgttgatgc aaacactggt
    31261 attgttacat tcactccagc taaaggtgta ggagaatcgg agccgattac tggaacaatt
    31321 cctattaaaa ttgtttacca agatggttct gtaggcacga ccgatttagc agtaactgta
    31381 agtaaagata tttatgaaaa tccaggagaa aacattcctg caggctacca caaagtaacc
    31441 ttcaccgcag g
//
LOCUS       DAIGQM010000032        31334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.032, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000032 DAIGQM010000000
VERSION     DAIGQM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.032"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            1..369
                     /locus_tag="NOA48_001436"
     CDS             1..369
                     /locus_tag="NOA48_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCI0789704.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="NOA48_001437"
     CDS             549..1490
                     /locus_tag="NOA48_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCI0789705.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="NOA48_001438"
     CDS             1559..2290
                     /locus_tag="NOA48_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCI0789706.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="NOA48_001439"
     CDS             2434..4614
                     /locus_tag="NOA48_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCI0789707.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="NOA48_001440"
     CDS             4634..5116
                     /locus_tag="NOA48_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCI0789708.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="NOA48_001441"
     CDS             5132..5893
                     /locus_tag="NOA48_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0789709.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="NOA48_001442"
     CDS             6024..7358
                     /locus_tag="NOA48_001442"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCI0789710.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="NOA48_001443"
     CDS             7665..8150
                     /locus_tag="NOA48_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCI0789711.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="NOA48_001444"
     CDS             8143..8826
                     /locus_tag="NOA48_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCI0789712.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="NOA48_001445"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="NOA48_001445"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCI0789713.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="NOA48_001446"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="NOA48_001446"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCI0789714.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="NOA48_001447"
     CDS             12442..13071
                     /locus_tag="NOA48_001447"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCI0789715.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="NOA48_001448"
     CDS             13123..13455
                     /locus_tag="NOA48_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0789716.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="NOA48_001449"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="NOA48_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCI0789717.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="NOA48_001450"
     CDS             14281..15654
                     /locus_tag="NOA48_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0789718.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="NOA48_001451"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="NOA48_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCI0789719.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="NOA48_001452"
     CDS             16709..17149
                     /locus_tag="NOA48_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI0789720.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="NOA48_001453"
     CDS             17293..17994
                     /locus_tag="NOA48_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCI0789721.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="NOA48_001454"
     CDS             17991..19112
                     /locus_tag="NOA48_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCI0789722.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="NOA48_001455"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="NOA48_001455"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCI0789723.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="NOA48_001456"
     CDS             20491..21399
                     /locus_tag="NOA48_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCI0789724.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="NOA48_001457"
     CDS             21434..21706
                     /locus_tag="NOA48_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCI0789725.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="NOA48_001458"
     CDS             21717..22763
                     /locus_tag="NOA48_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCI0789726.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="NOA48_001459"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="NOA48_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCI0789727.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="NOA48_001460"
     CDS             complement(25774..26460)
                     /locus_tag="NOA48_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789728.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="NOA48_001461"
     CDS             complement(26438..26932)
                     /locus_tag="NOA48_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0789729.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="NOA48_001462"
     CDS             complement(26952..28172)
                     /locus_tag="NOA48_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789730.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="NOA48_001463"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="NOA48_001463"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCI0789731.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30248..>31334)
                     /locus_tag="NOA48_001464"
     CDS             complement(30248..>31334)
                     /locus_tag="NOA48_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789732.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10431 a         5601 c         6715 g         8587 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggtagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gacgaggacg aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa
    30181 aaaataaacc atgtttacat ggatttgcca ccggtttgcc accggtggtt tttttcggtg
    30241 gcaaaaatca agaattcttt ctaagatttt ccatgatatc gaccgtttca tttctcatct
    30301 tatctgttac atgcgagtaa gtatccatcg taattgaaat tctgctgtgg cccaatcgtt
    30361 cagagatttc tttcattttt gcgccatttt cgagaagaag tgtagcatga gtatgtctga
    30421 gagaatggaa gttaaaagag agggagagtg cattcgatat cctcctagta ttccatttca
    30481 ctacacttgg cgtaactagc tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt
    30541 agagctttcc atacttcatt cgattttcta attgttgttt cttatgtttt ttcagaattg
    30601 ctagcaaggt ttgtccaata aaaatcgttc gattggaact gcttgtcttt ggcgtaccat
    30661 atacccatgc gccgtcattc tttaccattt gtttctctac agtaattgtt ccatttgaaa
    30721 aatcgacatc atcccacgtc agaccacaaa cttcgccaac gcgcattccc gtataaaatc
    30781 caatattcaa aggaatatag aaaggatgtc cttcaggagt aatttctagc atatgatcaa
    30841 agtcctcaag agaaatgatt tttagatctt ttttagtcgt tggtcgtgct tcatattttg
    30901 gtatttttac atacagcata ggattttgct tgattaatcc ccaaggataa accgccatat
    30961 tcagcgcatt cttaaggaca gagtgagtaa tagtcattgt tttcttcgag taaccctttt
    31021 taaattcagc attgatgaaa ttttgtaaaa gagcagggga gagatccgta agttttttct
    31081 ttcctaaata accgtttata tgatttttga tggtaaatcg gtagttttca taggtattgt
    31141 attttagatt tagtttaacg tattcctcca tccaaaaatc aaggtattgt tttactcgag
    31201 tatccgtacc taaaaagtat tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag
    31261 cagcttcggc ctctggtcgg gtgtctccgc caactttctc cacttttttt cttgagccat
    31321 catcattgat atct
//
LOCUS       DAIGQM010000033        30905 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.033, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000033 DAIGQM010000000
VERSION     DAIGQM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.033"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(12..2183)
                     /gene="copB"
                     /locus_tag="NOA48_001465"
     CDS             complement(12..2183)
                     /gene="copB"
                     /locus_tag="NOA48_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCI0789733.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2203..4389)
                     /locus_tag="NOA48_001466"
     CDS             complement(2203..4389)
                     /locus_tag="NOA48_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCI0789734.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="NOA48_001467"
     CDS             complement(4389..4598)
                     /gene="copZ"
                     /locus_tag="NOA48_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCI0789735.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4611..5051)
                     /locus_tag="NOA48_001468"
     CDS             complement(4611..5051)
                     /locus_tag="NOA48_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCI0789736.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5125..5664)
                     /locus_tag="NOA48_001469"
     CDS             complement(5125..5664)
                     /locus_tag="NOA48_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HCI0789737.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6279..7745)
                     /locus_tag="NOA48_001470"
     CDS             complement(6279..7745)
                     /locus_tag="NOA48_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0789738.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8056..10137)
                     /gene="cadA"
                     /locus_tag="NOA48_001471"
     CDS             complement(8056..10137)
                     /gene="cadA"
                     /locus_tag="NOA48_001471"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0789739.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10661..11020)
                     /locus_tag="NOA48_001472"
     CDS             complement(10661..11020)
                     /locus_tag="NOA48_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCI0789740.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11050..11391)
                     /locus_tag="NOA48_001473"
     CDS             complement(11050..11391)
                     /locus_tag="NOA48_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789741.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11388..12062)
                     /locus_tag="NOA48_001474"
     CDS             complement(11388..12062)
                     /locus_tag="NOA48_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0789742.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13115..14413)
                     /gene="asnS"
                     /locus_tag="NOA48_001475"
     CDS             complement(13115..14413)
                     /gene="asnS"
                     /locus_tag="NOA48_001475"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCI0789743.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14453..15643)
                     /locus_tag="NOA48_001476"
     CDS             complement(14453..15643)
                     /locus_tag="NOA48_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0789744.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15664..16191)
                     /locus_tag="NOA48_001477"
     CDS             complement(15664..16191)
                     /locus_tag="NOA48_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCI0789745.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16238..19027)
                     /locus_tag="NOA48_001478"
     CDS             complement(16238..19027)
                     /locus_tag="NOA48_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0789746.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19174..19374)
                     /locus_tag="NOA48_001479"
     CDS             complement(19174..19374)
                     /locus_tag="NOA48_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0789747.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19827..20147)
                     /locus_tag="NOA48_001480"
     CDS             complement(19827..20147)
                     /locus_tag="NOA48_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789748.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20650..21768)
                     /locus_tag="NOA48_001481"
     CDS             complement(20650..21768)
                     /locus_tag="NOA48_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789749.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22239..23546
                     /locus_tag="NOA48_001482"
     CDS             22239..23546
                     /locus_tag="NOA48_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCI0789750.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23667..24866
                     /locus_tag="NOA48_001483"
     CDS             23667..24866
                     /locus_tag="NOA48_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0789751.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(24893..26161)
                     /locus_tag="NOA48_001484"
     CDS             complement(24893..26161)
                     /locus_tag="NOA48_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCI0789752.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLFYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPILQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(26325..26972)
                     /locus_tag="NOA48_001485"
     CDS             complement(26325..26972)
                     /locus_tag="NOA48_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HCI0789753.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27381..27884)
                     /locus_tag="NOA48_001486"
     CDS             complement(27381..27884)
                     /locus_tag="NOA48_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0789754.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28007..28771)
                     /locus_tag="NOA48_001487"
     CDS             complement(28007..28771)
                     /locus_tag="NOA48_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCI0789755.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            28879..29154
                     /locus_tag="NOA48_001488"
     CDS             28879..29154
                     /locus_tag="NOA48_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCI0789756.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29819..30769
                     /gene="yidC"
                     /locus_tag="NOA48_001489"
     CDS             29819..30769
                     /gene="yidC"
                     /locus_tag="NOA48_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0789757.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT         8806 a         6631 c         5444 g        10024 t
ORIGIN      
        1 ttttttcatt attatttgat tttcaatgtc aaagcattta gagctacaac taccgtactt
       61 aacgacatca agacagcacc aactgctgga cttaatatga taccaattgg cgcaagaatt
      121 ccggctgcta gcggaattgc aagaatattg taacctgccc cccaccagag gttctggatc
      181 attttctttc gcgtttgctt ggctagatca agaaaatgca aaatatcttt tggatcgctg
      241 tttgtcaata cgacatccgc agaatcgatt gcgatatctg tccctgcacc gattgccatc
      301 ccgattgaag cacgggctaa acttggcgca tcattgatcc catcacccac catgattact
      361 tttttccctt ggtcaaggta tttctggaca acagcttctt tatcatctgg taataaaccg
      421 ccataatatt cttcgatccc taaataatct gctactgctt gggcagcgtt tttattgtca
      481 ccagtaagca tgacaggagt gatttttctt tctttcaatg ttcggataaa ttcttttgct
      541 tctgttttta ctacgtcacc taaagcaacg attgcagcta gatgattttc taaaatcagg
      601 aagctgatgg tatttccttg ttcttggtaa ggtttcaata atgcttgttc tacgtttaat
      661 ccgagacgct caacttcttt ttcattaact attttcactt gttgtttttt gactgttgcc
      721 tctagcccga ctcctgaaag attttttaga ttttcagctt gataaggctt gatttcatgt
      781 tctttcaaat aattcataat gccaacagcc aatggatgat tggcattcgc ttccaaggct
      841 cctagatatt gaaggatttc atttttattg aacgcatcat caagtacttc gacacccgtt
      901 acagtaaatt ttccttctgt tagtgttcct gttttgtcca gcatgatcac atctagatca
      961 ttggcttgct ccagtgcatt gcggtttttc aaaagtaatc cgtttttagc tgctattgat
     1021 gtggagcgag caacaactaa tgggatagct aaacctagag catgaggaca ggcgatgata
     1081 aagactgtta ccatacgttc taatgcatta ggaagatctg tcaagaacaa ccaggcgatg
     1141 aatgccagga tacccacaat taatgcgaca taaaacagcc attttgccac tttgtcagat
     1201 aatgactcta gcttggattt ttctccttgt gcttttcgca ccatttccat aaccttcgct
     1261 agataaccat tttcaccagt tccagttact tcgatttcga tcgttccatc cccattgata
     1321 gaaccgccaa tcactttgtc attggcttgt tttttgattc ctcttgattc gccagtcaca
     1381 gctgattcgt caacaattgt ttcacctttc aagattacac catctgttgg cattttatca
     1441 ccagaccgga cgatcaaacg atcaccttcg tttacttctt tcaatgaaac tgtctcttct
     1501 tttccatctt tcgtcaagcg tttcactgat tctggcagta attctgctag tttttgtaaa
     1561 gcattgctgg cattcgacac agcattcatt tcaatccagt gacctagtag cataataacg
     1621 atcaaagtag ccaattccca gaagaaatcc atgacgtgtg tatgtggatt gagcagattt
     1681 gcgataaacg aatagacact ataaatatat gcaactgtaa tccccatcgc gatcagtgtc
     1741 atcatagcag gacttttttg tttcaattcc atcttagctc cacttaaaaa tggctgaccg
     1801 ccatagataa atagtatagt tgctaagatc aatacgagcc aatcagaacc aggaaacgtt
     1861 acttgaaatg gaaattccat tcccatcatt ggtgaaaaaa gaatgattgg gatagctagg
     1921 ataagcgata gccaaaattt ttgtttgaaa ttccccatgt gcatggaatg atccatgccg
     1981 ccgtgttcgt gatccatgtg catcgaatgg tccatttgtt tgctgtttgc tatatctcca
     2041 tggttatgtc ccatgtgcat ggaatgatcc atctgactat ggtcatgttt catctccatc
     2101 tgtttttcat gagattctgt actttctttg tttactactt cttttttatg ctcatgtttt
     2161 ttctccatat cgttcccatt catttttact ccatcccttc tcttactttt tcatgtgtcg
     2221 atttaagctc agggagttca acaatacact gacggaacta aacgccatcg ctcctcctgc
     2281 aatgattgga ttcaaaaagc ctagtgcggc aaaaggaata ccaatcgtat tatagacaaa
     2341 agcccagaaa agattttgtt tgatttttct caatgtcaac ctagacaact cgattgtttg
     2401 tgcaatggat gccaaactgc tattcatcag cgtcacatcg gctgtttcca tcgcaatgtc
     2461 cgttccactt cccattgcca taccgacatc agctaatgct aaggccggtg catcattgat
     2521 tccatcgcct gccataccga cttttttgcc atctttctga agtttttcta cgtaggctgc
     2581 tttatcctct ggaagtactt cagcaaagat atgctttgga tcaataccaa cttgtttacc
     2641 aatcgtttcg gctgccagtt tgttgtctcc tgtcagcata aaaacatcta atcctttatt
     2701 ctggagctgc ttgattgctt gtttggcttc tagtttgatt tgatcagcca cggcaatcca
     2761 cccgatcact tgcttttcat cagctaaaaa catgactgtt tttccctgct gttctaattc
     2821 taacgcgtgt tcttggtatt catcaaatga taggttcaat tcaattaatc gtttacgtgt
     2881 acccgcaaaa tagcgtactc cattaatcgt accgctgatc ccagcacctg ggtgggctgt
     2941 aaaatcaatc atatcgtatg ttgctgcttc ttgcagtttt ccgtattcca cgattgcttt
     3001 acctagtgga tgttcagaag cttgttctaa agtataaaaa atagatagga cttcttttga
     3061 accgactaga tctgtaactt tgggctttcc ttctgtaatc gttccagttt tatccaaaac
     3121 aatgctgtct aagtgagcag ctgcttctaa tgcttctccg cctttaatta aaattccatt
     3181 tcgtgcacca acacccgttc ctaccataat agctgttggg gtcgctaaac ctaatgcaca
     3241 tggacacgca atgactaata cagagacact atggatcaat gcgagttgcc aatcaccagt
     3301 gatcaaacct gtagctatga gcgtgataaa cgcgatgact aatacgatcg gaacaaaaat
     3361 ccctgagatc cgatctgcga ttttttggat tggggctttg ctcccttgag catcttccac
     3421 catttgaatg atttgcgcta atactgtctg cttgccgact tgtgtgactt ccatgtgtag
     3481 cagaccattc gtattgattg tcccgccaaa aagcgtgtca tccggattct tttctacagg
     3541 aagattttca ccagtaagca tactttcatc tatcgcactg cttcctgaaa taattcgacc
     3601 atctgctgga atctgctcac caggacggat gactagttga tcaccaacga ctacttcttc
     3661 aatcgctaac gtttcttctt tcccgtttct tatcacttgg gcggtttttg tttgaagaga
     3721 catcaattgt ttgattgcat tacctgtttt cgtttttgct gtatgttcca aatatttgcc
     3781 gagcaaaatc agcgtgatga tcatactgct gctttcaaaa taaagatctt gggggtgtcc
     3841 acggaaaaat ccgttgtaaa tgctcaatgc aaaggcagcc gatgttccaa ttgctaccaa
     3901 tacatccata tttggtgctt tcgtcttgat tgcatggtac gcacctttat aaaaacgagc
     3961 accgacataa aattggacag gagcagacag cactaactgg acgattggaa aatgaaaaaa
     4021 gtgaacaatc gccgcatggc ttcctaacat catagcaatc attgacaaca tcaacggcaa
     4081 agtcaaaacc gtactcaata taagatcgaa tagcattttt ttcaaatacg cttgcttttc
     4141 ttctgcaatt ttttgtttgt gggcttcatc gtacaaaatt gcaccataac cgatgttttc
     4201 tacgctttgg attaattttt cagtggtcgt cccttcatat ttgacacttg ctttttcagt
     4261 ggccaagttg actgtggcat tgaccacacc aggttgtccg ttcagctctt tttcgatcct
     4321 agcagaacaa tttgcacaag tcatacctgt aatgacgaac gtatccattt tggtttctgc
     4381 tgttgccatc aaatcacctc tgctttataa cccaatccat tgattgcttg acaaatcttt
     4441 tcggattgaa cttttgtttc atcaaacttg accgtaccgt ttgctttttt caaatttact
     4501 ttcacttttt gcacgccgtc aagtgcgctt actgtttctt ctactcttgc tgcacaatga
     4561 ttgcagctca taccttcgat tgaaaattgt tgtttcattt tttcttcctc ctattgatgt
     4621 tgtttacatt cacattgacc tgggatacag ttacattcga tcgtatctac tggttgcttt
     4681 tgttccagtt gtttcaaaat ctcattgata tcttcttgag tcaaagtggc ttcttctact
     4741 agatccgcaa tcgtctctcc aatccttttt gcacagatat gggaaaaaag attttccgtc
     4801 gcactgcgaa ctgtttccat ctccgagaca gctggatgat aaatgaattt ttttccttct
     4861 tgttctgtcc agatcacttc tttttttacc aaacgtccca gcaaagtttt gatcgttgct
     4921 ggtttccaat ccatcgaatc agctaagatc tgcgtgattt cttgggctgt cgtctgtcca
     4981 agtgtccaaa taacacgcat gatctcccac tctgaatcac tgatctttac tggcgttttg
     5041 actttttcca tttatttcac acctttcgtt tacaaatgta atcattagct tatgaataca
     5101 gattacgctt gtaaacaaaa actgtcaatt atttttgctc tctattttca atttagttaa
     5161 aaattcttgt ttctctcgtc ttgttttaag gatgatcagt ttatttcttg cattagctac
     5221 ttggatcagc tgctgtattt tcggttcatt gttttcttca aaatgccaga taaaagataa
     5281 aaattctaag tattccctgt ttagtttctc tgaaaatgat tcaggcatat ctggccgaga
     5341 ttttttgttt atctttcttt ttagagaacg ccaaactact cggtagatgg cgagataacg
     5401 cggcacttta agccaaatga tcttatctgc ttctttaatc ctttcctcta atgtagaagt
     5461 ataatttcct tcaacaatcc atgacggatt agataccata aacgattgct gttcttgcaa
     5521 aaaccacttt tttgcctgaa tactgtagtc tgttgtatgc cataaaaggt ctagcggcag
     5581 tagcggaaag tcggtgattt ctttgatctt ccttgcgagg gtcgattttc ccgacccact
     5641 ttgtccaatc acgatgatct tcattcttct ccctcacttc tctttggaat ttggttcgat
     5701 cataccactt ataacgccgc aaaaaaacaa gggactgtga caaaagtcgt gtcaaagtcc
     5761 cttgtttcga ataaatggtg ttcaatcagc tgaccttcag cattaactca aaaaacggca
     5821 aaatatgagg agctattttt tcgtttgttc ctctaatact caggtcaaat cgctgatttt
     5881 acaacctctt ccttaaacgg tgttctcctg ccaacacctc ggtcacaagg cacaatagtc
     5941 aacaaacatg agaagttgtt ttttgaaatt gctccttgtg actcggagtt aaacggcagg
     6001 ctcactacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccagca
     6061 aaacgaaaaa tatgaggggc tatttttgtt tggctgttct tattacttga tgcaggacag
     6121 ctttttcaca acctctgatt cacggtgttc cagaagtagc ttctgcgaaa aacaagccga
     6181 aacttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
     6241 cacttctgtc acaacctctt gtaacaagta tttctatttt aaggctgaac cactgtttct
     6301 ggttcagtga tttctttgtt tttgtctcga cgagcaattg ctggcaagat catacctaat
     6361 aagatcaaga caattggtgt gatgatattc gtgaataatt ggaaccacca tgctttagga
     6421 tcagcagtat aatctacttt tggcaccatt cctaggatac atgcaaacgc agtgaaggca
     6481 aagcaccaag caccaaagat aaaaccgatt tttggatttt taacaaattt atattcagaa
     6541 ttgaatttct tataagcttt attcaacatc atatatgcca agaacaccca taggtaacgc
     6601 attggcatga caactgagtt caagttcgtc aaccatttta ctaattcatt catatctttg
     6661 ataccaaaga tcggcaacaa aataatgatt cctactagta tacctgtcag aagataacca
     6721 ttcaccaatg tacctttacg attacgttta cgtagccagt ttggtacaaa ttctggatcc
     6781 gcatctgcta acaagatttt tagtggtgca tcaattgaaa aggctaatgc ggagatttgt
     6841 ccaatcatgt ttgtcaatgc gtaaatgatc atcaatgagt taccgatacc atagtaatta
     6901 cctaaaattt gaaaagcact gtatgcccca tttgccatca agtctttagg aatattatcg
     6961 ctagcaaaca gcatacccat tgcgactgag cctaatacag cacaaatccc taccattgct
     7021 gctaagaaga tcatcccttt aggaaattcc tttgcaggat ttcttgtaga gttgacataa
     7081 ggggatattt tttccgctcc tccaactgca aatactagca tcgaaacggt tgtgaaataa
     7141 ctgaaatcaa atgttggaat atatgttttc acttgattca tatgtggtgt ggcaaattcc
     7201 atcgttggat tgatgaacgg tgccgttaca gctaaaagaa taaataagat cgacatgacg
     7261 aacatcgctg ttccggccag tccgccaatc actttcaaag tagaaagtcc ttttgttgat
     7321 aaatataaaa aggcaagaaa tataataagt gaaataactg ctaccatttg tactgacatc
     7381 gtatttacga tatttccatt tccttggact gcccaaccgc cagcaatcag gattgcttga
     7441 ggcttttgtg ccaaataagg aatatggacg acccagtaag tccaagcggc atagtatgcc
     7501 agtcgtttat tagatgtcgt attttcgacc catgaactga cgcctccttt actatccttg
     7561 aaggctgacc ctaattgtcc aacgatcaat gcgtatggaa taaaataaat ggccaaaatc
     7621 aatagccaag aggtgacaac tgatactcct tgctgagcat agttattaac tacattcccc
     7681 atgccccaaa ccatgttaaa tgcaattaac gcaacagtaa accagcgtaa ttgtttgttg
     7741 ttcattcgtt ctctccttta tgataaaaat ttgttatcca gatgtaatca tattcaattt
     7801 ttaacaaact tacaagacag tgttatttta tgtgtgtatt cttttattta atacacatcg
     7861 ttttttcata ttttttccat caaaaaaata agttattttc ttttatttca tttaccttat
     7921 tgaatttcaa gctattttga attttctgca aaattaaaaa cattagttat tttataatcc
     7981 tatctatttt ctttacattt ttcattaaga aaaggatata aaaaaaagag gacgttcatt
     8041 cgtcctcttc attgatcaac gtttattttt tacatgcaag cttcgcatgg cattcaaaac
     8101 agctaatact gtcaccccaa catctgcaaa tactgcatct cccattgatg caaaaccaaa
     8161 agcacctaag gcaagtacca aaatttttat cccaatagca aagacaatgt tctgtttgac
     8221 gattttcaat gttttctttg ctaaatggat tgcttctgca atcttcgatg gttgatcatt
     8281 catgatgact acatctgctg cttcaattgc agcatcgctt cccaatccac ccattgcgat
     8341 tcctacatct gctcttgcta gcaccggtgc atcgttgatt ccatctccga caaatgcggt
     8401 ctttttattg tttctttgta agatttcctc taaccgctgc actttatctt ctggaagcaa
     8461 ttcgctatat atcttgtcca cgcctacttg cttcccgata tgatcagcaa tttttttcga
     8521 atcgcccgtc aacatgactg tgttcttcac accagccttt tttaattgaa ccaatgcgtc
     8581 tacggcatct tctttcaagg tatctgcaat aacaagataa ccactgtaac tttgatcgat
     8641 cgctagataa agcaatgtac cgatttcttg acttgaagga aaagagattt caaatctttc
     8701 catcaatttg tgattacctg ctaatacttg tttgccatca acttcagcta agatcccttc
     8761 acctgcaaat tcttggatat tagctgttgg taaaagcgga cctgcgtagc cttctaaaac
     8821 agattgagca atcggatgtg tagaaaactg ttctgcactc gcaacatatt gcatgaatat
     8881 ctttggatcg atttttgtat cgatcgtctg gatcgaaaag tcacctttcg ttaatgtgcc
     8941 ggttttatcg aataccactg tctcagtttg tgcaagcaac tccaagtaat ttgaaccttt
     9001 tactaataca ccgattttac ttgctcctcc gataccgcca aagaaactaa ggggtacgga
     9061 gatcactaat gcacatggac atgagatcac taaaaatgtc aatgctcgat agatccattc
     9121 agaaaacgcc gctccagaaa caacaagtgg aggtaaaaca gctaataaaa cggccaatcc
     9181 tacaacgact ggtgtgtaat agcgcgcgaa tttagtaatg aaattttcag ctggtgcttt
     9241 tttactgctg gcattttcta ctaattctaa taatttgctg atagtagaat tttcataaga
     9301 tttttctact tgaactaaaa atggtttatt tttattgata aatccactta atactgtttc
     9361 accaacatat acagatttag ggactgattc tcctgtaagt gctgacgtat cgactaatga
     9421 ttctccttcg atgatcgttc catctaacgg tacacgttca ccaggcttca caagtacaaa
     9481 ctgaccgatc tgcacgtctt cagggttcac ggtcatcaat ccttccgtcg tctgcacgtg
     9541 agctgtttct ggacggatcg ccatcaattc gcgaatcgat tttcttgaat gactgactgc
     9601 caatccttgg aaatactcgc cgatttgata aaatagcatc actgctacgg cttctggata
     9661 ttcaccgatc aacatagcgc caatcgtagc aacagacata agaaaattct catcaaagat
     9721 ttttcctttg acgatattca tcactgcctt cttcactaca tcatatccta tcagcagata
     9781 aatcaataaa taccctatca agcgaattgg ttcattaaaa tcaaataata gcaataaagc
     9841 gatacctgca agggaaaata aaatccggaa cagcgtattt ctctcttttt catttccatg
     9901 ttcagatact ttttccttat ctatttctgt tactttgaca tctggttcta attccttcac
     9961 tacttttttt atttcttgtt caatcgtagc caaatgatct tcctctgcgt caatcgttag
    10021 ttttccagaa gtgaagttta ccgttgcttc cttgactcca ttgatcttct gaactccttt
    10081 ttcgattttc attgcacagt tcgcacaatc taaaccttct aatctgtaac ttttcatttt
    10141 aatgacctcc tcgcctcaac atatgaatat ctcttcataa ctaattataa atgaacggtt
    10201 attcatatgt caaggtatcc gaaagaaaaa atgaaaaaca tctgcatcgg aaaatttctt
    10261 ccatacagat gttttggctt attctttctt tttcttttcg atcattgcca ctgctcttat
    10321 ccaacccgca cttgccttct tgatcttgac aggatagcaa ctaagtttga agcctgttgc
    10381 tggcaatttg tctaaattca ttaatttttc gataggacaa tatctttttt caatccctgc
    10441 aaaatgtcct tcccagatat tcgaagctcc actacgcttt caaaaatata gaaagagttc
    10501 tttaatgaaa attatttcaa ctttccataa acagtaaccc catataaata aaagacgtaa
    10561 aagtcacatg gaagaactta tacaggagaa cgcatagagt caggtgaaat acatgtatcc
    10621 cacctgactc tatgctttat ctaaccttta ttattctctt ttatacaatt tctgcaccga
    10681 atggcatcaa cgccaatcga gcaagtttga aagattgctt ggcaaaaggt atccctatga
    10741 tcgtgataca tagaaggatg ccgctgacga catgtgcgag agcaattggt aggcctgaaa
    10801 cgatcagcca gatgatatta acaatcaatg acatgccaga ctggtgataa attacttctt
    10861 tgccaaaagg cgcaaaagaa agggaggcga tcttaaaaca ttgcataccg attgggatac
    10921 ctatgatcgt gatacaccaa agtatccccg ctgctaacca gctaagacca ccgattagtc
    10981 cgccgaatat aaaccagatg acatttccta aacaactcat tgtatttctc cttctattac
    11041 tgtttttgat taaaactggg caaaaaatga ttttattctt ctttttttag cttccagtat
    11101 caaatattct gcaaattttt tttggatttc ttccgtattt tcttttgtta ctaatgtgtg
    11161 ttggattagt tttcctgatg gtcgctgatc caatcgttct tctgactgtt gcacgtccgc
    11221 ttgcgcaaat ccgataatcc gtttttcttt tgttacagca acgagcaata gtttattctt
    11281 atcatttagg tcagctgccg tttttgcttt tacgaatgat tctggatgat cagtaatcag
    11341 ctgattgatt tgaggtagat cttcttttac tgcccaccgt atttccatca tttctcactt
    11401 ttctttcgct catttttatc tccactaaaa aaatcgactg cggcaattgc atctatccag
    11461 ctttgtgcaa tgatctcatg tccgccaatc gttgggtgga ccccatcttc tcttgtatat
    11521 ttcgaaaaac cataaacaat ccctaaagca ttgaatatac catctaaagg aaccagcaat
    11581 gcgccatatt ccttagcaag tttacgaaca atttggattt tagggtctaa gtctttacgc
    11641 cagccatgac ggtcgtcggt tataggaagt acaaacggct ccatcaagat gatgttgcag
    11701 attcccactg tttgaagttc atttagtaat tttcgataaa cggattcaaa ttgctgagca
    11761 gatttctcag ttccgaatat agcctgatcg ctagtattat gccaggtatc attgattccg
    11821 atcaaaatcg atacatagtc aggttgtaaa gctaaacaat cttcttgcca gcgtacttgc
    11881 agatctgcaa ttttgtctcc tcctatccca cggttcatgc attcaaattc catcgttgga
    11941 tattgggaga ttagttttcc ggcaatcaaa agtggataac ctttacctag atcagttgct
    12001 tctgctcggt ctcttcctgc gtctgtaatg ctatcaccga taaataatat acgttttttc
    12061 atttgtcaaa aactcctttt tgaataaaac gatgattttc ttccttatat tatcccataa
    12121 gccctatcaa gacgaaagag aaaatatatg tataaaaaat gacaccagcc tagtcccttc
    12181 aaacaattga atgaacgctc atcaagtgtc tagtttttta tgctattttt ttcttaacgt
    12241 gccggattcc ccttgattcc ttcgttgttt ggtccagaga gatcgatcac acctaagctt
    12301 ccgtcaatca gaccactgat gacgccatca gaacatatat ttataggctc atctaagact
    12361 tctagtaaat gtccctttac taatatctct tctagattgc ttgggataga ttggtcataa
    12421 ctttatctgg tccgatgatt tcaagggtga attgaactta catatggatt attgcatgct
    12481 gaaaatacgg acctactcca tcttcgaatg ttactattag tttgttttca ggtgctagat
    12541 gctgctttat ttcaacagca gaagcatcat caaatcagat ttccatttga attaccttct
    12601 ttgtaaatgt ttgattgatt gcgatttcgt tatagaacct tgtgaatcaa atagcaattt
    12661 cttttgcttt cttctcttgt ctgctggaaa cttcctttat cccgtatttt aaaaaaagaa
    12721 ctgcgagagt tcgcagttct tttttagaat aaacggtgct ctccggccaa ctcctcggtc
    12781 acaagtcaca atagtcatca aacatgaaaa actgtttttt gaaattactc cttgtgactc
    12841 ggagctgaac ggcaggcgca caacctcttc cttaaacggt gttcaaaagc cagtttctcg
    12901 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt ccacaaaatt tttcttaata
    12961 ctcgaaacta aacagctttt tcacaacctc tccactaaac ggtattcaaa agcttacatc
    13021 tgcggtaata agtcccgcca attcaaaaac atgaacagct gtttttgctt ggctgttcta
    13081 attacttgat gcagaacagc tttttcatca cctcttatgg ataaattcgg ttcaacaaac
    13141 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    13201 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    13261 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    13321 ctgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    13381 cacagatcac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    13441 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    13501 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    13561 tcgcatcatc ataagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    13621 tgtctcgtcc tagtacatct aatgcatatt cgcaatgatc taaaacattt tgtactaaga
    13681 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    13741 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    13801 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    13861 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    13921 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    13981 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    14041 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    14101 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    14161 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    14221 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    14281 ggaaaaaggc tgttccgtct cttaattgta aaaatgcgat ttttccgctt gatcgcttat
    14341 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    14401 gaatttgttc cacgtatgac tctcctttta tattccttga atttctttag gattaatttt
    14461 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    14521 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    14581 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    14641 tgcgtagcgt ttcttttaca ttaggaaaaa gataaaaagc tccttgtggc ttttcaagag
    14701 aaacacccgg cagttctgcc acaagcgaat ataacgtatt caggcgttct tcaaaggcgt
    14761 tccgcatttc ttccactgta tcttgctcgc ctttcaatgc ttcaacagct gcatattgac
    14821 tgactgctgt cggattactg gttgactggg aagcaacagc gatcattcca ttgatgatca
    14881 caggatttcc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    14941 cgttgatgat gatagtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    15001 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    15061 ttactgccca ttcaccgatt gcctgcagtt cattcttgct ataaatcatt ccagtcggat
    15121 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    15181 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    15241 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    15301 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    15361 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    15421 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttccca ttgcggattg
    15481 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    15541 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    15601 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    15661 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    15721 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    15781 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    15841 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    15901 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    15961 ctttcgagta aaccaataaa aatgatcggt ttcctcaaga tttgcatatt tctttgcgat
    16021 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    16081 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    16141 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    16201 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    16261 ttaagaattc atggatatcc tgatagattt cctccatagc tagctctttg atcggtactt
    16321 ttttcggtaa tgcatggatg atccgtgcgc catattttgc agtgactagt cttcgatcca
    16381 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    16441 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    16501 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    16561 ctacaacgat ctgcaaagca tctccaggca aatctacacc ttcccaaaag ctgtcagcgc
    16621 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccac
    16681 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    16741 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    16801 cgatcagacc tgtaagtgct gtctctaaat aatcgatata tgcttgattg ctgacttgat
    16861 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    16921 aggcaatcac tttaagaggt gctgcttcaa tgccaagcct cttagagaga tagtgtcgat
    16981 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    17041 cagtcgacgg caacatagcc gcttgaaaat catggagatg aaaaatcatc tgctgcgctg
    17101 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    17161 tcagcaagta ttgcttgtct aattgatcaa ataggctata taaacttgct aaatcgatcc
    17221 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    17281 gctgctggat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    17341 gcagctgatc caacatctct tttgtcatca tgacttcttc tggatactgt ccgttaggtt
    17401 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    17461 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    17521 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    17581 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    17641 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    17701 gtactaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    17761 aacgaacaaa gtcttgttcg taaaatgact gatttcttgc taaaaatcca atacctctgt
    17821 gcgcgatatc tgcaaagaat gaatggttca aatttgttaa atgtaattca tccaaatcac
    17881 cagtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    17941 gttctggcgg ttccacaagt gtgcctttaa aacgctgcaa atcaatatag tggcgatagc
    18001 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatgtctt
    18061 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    18121 gtgtagccaa ataactcaat ggcagcagat aaccgattgt tttacccatt cctgtagctg
    18181 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagacc gcattcatca
    18241 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa cattttttct tttgcttgtt
    18301 tttttcttgg atatgtccgc tcgccataat ggacggatgt gaatagttcc acttcttttt
    18361 tctgcaaagc tagcccatcg acgatttcta atgagggatc aagtggctct ggtttttctt
    18421 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    18481 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    18541 aaagaagttg acctgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    18601 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    18661 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    18721 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    18781 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    18841 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    18901 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    18961 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    19021 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    19081 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    19141 atgtctgggc gtttattttt tagtataggt taattaagct ttagtaacgt ttgttgcttg
    19201 aggtccgcgt tggccttctt caacatcgaa agttactgct tggccttctt ctaaagtttt
    19261 gaatccgtcg ccttggatag ctgagaaatg aacgaataca tcgtttccgt tttctgcagt
    19321 gatgaatcca aatccttttt ctgagttaaa ccattttact gtacctgttt ccataataaa
    19381 aatcctcctt gtgtatcaac acatattttg caattacttg aatggtgtat atctggaaga
    19441 tgtttatttg aaacaagcta ccacagatta ccgaacaaaa actactccta tagtatatca
    19501 taccgtttac aaaaaagcta gagtttttcg acttttttta ttaaaaaaag ttttctcagc
    19561 gattacataa agtgaaaaac cgaacttttt tttaaaataa acgacatatt gttcagttgg
    19621 tgtttttttg ctctgatgtt cttttttaaa ctaaaaaaat tattctttct gactacttat
    19681 cggttctgtt tcaacggtcg aggctgggga agattcttta gtaggtctga tgttctcatg
    19741 gtatttctga tagcctatga cagttaccag aagaacaagg caaaccaata cgaccaacga
    19801 gattagtttt tcttttttgc tcatatctat acctcataaa taacaggatg atgtccatca
    19861 tatttctgag tatgagtaaa agcaaaagct gcagctgtag aatgtaagaa atgccagcaa
    19921 ctttcataat cacaggtcgg acagtaccaa aagtaaccaa atcttggctg caaagaccgt
    19981 tcttctgttt caggaatcgc agaatcaaga tctggtgtct gtacataaac atttttgtac
    20041 agacgtgtgc ctgtaatagg aaaccgctgt gtttcttcag caaaaactgg ctgacttgtt
    20101 aaacttaggg atagagacag caaacaccat aacagtcttt ttttcataaa gacctcctta
    20161 tcgataagtt tttcccaatt aaaatcatat ctcaagaacg cccgttattc acattttgtt
    20221 cataaatgat gttttttgta tcataatcgt caaaaagagg tcgtgaccac gtcacaacct
    20281 cttttttaaa cggtgttcca gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa
    20341 tttgagaaat aatttttgtc aatctcttct tatttcttga agctgaccac ttctgtcaca
    20401 acctcttcct taaacggtgt tcaaaagctt gcatctgcgg taataagccc accaaacaaa
    20461 aaatatgaag agctattttt gcttgctgtt cttattactt gatgcagaac agctttttca
    20521 caacctctca tacacggtgt ttaatcagct gaccttcggt attagctcaa aaaacggcaa
    20581 aatatgtgaa actatttttc cgtttgtttc tctaatactc aggtcaaaac actgatttca
    20641 caacctcttt taataacgaa gaatcgctgt cagactcttt tcatctggcg catctttttg
    20701 atccaaaata aacacttttc cgccattaat gatcacatca tctgctaatg cattcaacac
    20761 ttgacgccga tcatattctg tttcaggatc ttcaccgaaa ccatcagcta agtttgacgt
    20821 agcgataaat aaatgtgaca cttttccttc tttcgcagct ggaacgatat caactaactg
    20881 atcgatgaat ttcttatcta agagtttatt gtattctttt gattcttgag ctgcgagttc
    20941 acttgacagc ttcttcgccc cttcttcgat atctctaaag gatagctgcg caggagaagc
    21001 agaaatcgca acgtctgcac aataataggg atttttagca atttttttga acatcgtctg
    21061 attttctggt agagcaaata aataaatcgg ccattgttct ggattttcga aagaatcctt
    21121 caagtacgta tcaactgctt ggtaatagtt gacccaatcg atctctactt cttcatcttt
    21181 tggatttacg ccatggaaag ttactccatc tcgggctccg cctcctccat tagaagagaa
    21241 gttcaaaccg ccacctgtca gttcagatcc caatgcagta acgacatcaa ccggtgcccc
    21301 ttctggtaga gatacttctt ttacttgttt gttgctgact tcatacaatt tcatggagtc
    21361 gcggttcaat cccaataaat aataagaata gttgaactgc ccatttttga taatagccag
    21421 taaataagga agatcactta catagtattg atcgtctacc gggatactca aacgatggat
    21481 ataggtttgg tcagcagtta taatgaccgc tacactcgta gttgcactac gccaaaacga
    21541 aggatctcct aacaaatttt caattttttc ttggaacggg gaccagtcat gttcggaata
    21601 ttttttctca aaacgtttct ttgcttcttt cgcaaaattt ttgaatttga tctgatcttt
    21661 ttccacatct tgatgggcga catgcgtatt cagcatgatc gtgacgaatg gtcctttagc
    21721 gccttctgaa gtcaattgtg acaataattc tttatccttt tttgccataa acgtacccct
    21781 cctaaaaaaa tcattccttt gtttctatct aaagtctacc acaacactat ttttccatac
    21841 aataaaacgt atctaaaaaa ataaaacggt ttctacggtt ttaaatttag ctattttttt
    21901 aagttatctt cataatttcc tcaattattt agccccagtc ttcaactatt cttcatgaaa
    21961 tgctgataaa ctaagaaaaa gaataaaaga ggtggatctt atgcatttga ttatgatttt
    22021 cagtttatta agtattatca gtttatttgc tttcagcgct tcccgcttat tagatgcgga
    22081 aacacagcct attcctgtaa aagtacgtaa aaacgaccgc taaccttcca taacgtgcgt
    22141 tcttatccta aagttttttc agaaacattg aaactctctc ccctctctga taaaatttta
    22201 atttgtagcg aaacaaatta attacaagga gatcggatat gtccataaaa aaaacacgtc
    22261 tagtcctatt attggctagt ctcattcttt gccttgcttc ttttctacca gctgttgctg
    22321 tgcaagctga agatactttc aaagtaaatg caaaagcagc ctttgctgta gatgcgcaaa
    22381 gcggtaagat tctttatgat caagatggag aaaaaaccat ggggatcgct tcaatcacaa
    22441 aaattatcgg tctttacatc gtccttgatc aagtaaaaga agggaaacta tcatgggatg
    22501 ataaagtttc aatttcagat tatgcagaaa atttgagtgt caccccagat ttatcaaatg
    22561 ttcctttgca taaagaaaac acctacaccg ttaaagaatt attcgactct gcaatcatcc
    22621 agtcagccaa cgcttcaatg gttgccttgg cagaaaaaat ctctggcagc gaagcaaaat
    22681 tcactgaacg aatgaaagaa caattgaaag attggggtat caaagatgca acgatcgtta
    22741 atgcatcagg actgaataac tcttatcttg gcgaaaaccg accagaaggt actggagaaa
    22801 acgacgaaaa tcaaatgtct gctcaagatg tggctatcgt tgcccgtcat ttgatcttgg
    22861 attttccaga aatactggat gtatctagca ctacgacaca aatgtttggc gaaaacacgc
    22921 aatcaccagt agaaatggtc aactggaact ggatgctccc aggattcgtg aattataaag
    22981 aaggcgtgga cggattaaaa actggtacga ctgaacttgc aggagcctgt ttcgtcggta
    23041 cgatcactaa aaacgatcaa cgaatcatca ctgtcgtatt gaatgcagac ggccatgcgg
    23101 aaaacccaag tgcccgtttc aatgaaacag ctcgcttaat ggattattgc tacgacaatt
    23161 ggtcagaaaa agagcttgga aaagccaatg caagtatccc tagtctaaaa accattgatg
    23221 taaaagacgg aaaagaatca acagtgcccg ttgtgcttaa aagtcctgta aaagtatggg
    23281 tacggaacga tatggatact ggaaaattaa caatcacacc aactcttgac aaaaaacaag
    23341 tcactgacaa tgagatccaa gcacctatgg ataaaggaac aaaaatcggt accgcaacga
    23401 tcaccttggc agaagataaa ttaggttatc tagaagacaa caacgcgcca tccacagaaa
    23461 tcatcacgga taaaaccgta gaaaaagcaa atattttcgt tattggctgg cgacgcgtcg
    23521 cagaattttt cggtaacttg ttttaattga acaaaaagaa aaaagcatct ttccatgtgg
    23581 aagatgtttt tttgcttttt ctagtttaaa taacagcttt tttcatctat tttcgttata
    23641 ctgtataaga aaaaggagtt gaatttatga atctaaccag agatctgatt tttttggttc
    23701 tctatcttat tggggtattc tccatcgttt attggcgaaa acagaaaaag gatccttcct
    23761 tgttctttta cagcagtacg tggacatttg cggtaatctt gacttatttt gtcgtgttgg
    23821 aaatttttta ttcgaccttt tattttttga ttcccttagt gtttttcagt atctttgcct
    23881 tttcctattt ttcagaaaag cgaaggctgc tgaatggtct tttattcaat gttttcctca
    23941 ttagttttgg tatctacttg tttgtcttgc tatacgaaac acaaaatatt tttcttggcg
    24001 gactgattgc cttgatcacg atcccgttac tgcttgtctt tctattcggc atttatggat
    24061 tgatcgtttt tcttttttgg aacggtgtca cagttttacg tagagagtcg cattcattag
    24121 ctaatctttt aacgttgata ctagccattt ttcttacatt gtttcttgtt tttgactttt
    24181 tcttgttaaa atatttacca caatggataa atgctttgtt tttctgcatc ccattgatct
    24241 tgatctatct atttatcgta ttctacaact ttttgactgt ctcattcttg tatcagttca
    24301 accgccctcg atacaaccaa gacttcatcg ttgtgttagg cgccgggttg atcaatggag
    24361 aaacagtttc tcctcttctt gccaagcgaa tcaataaggc gattgctttt tattgggcac
    24421 aaagccgtgc gacattaaat ccgcctatcc tattaatgtc gggtggacag ggagcagacg
    24481 aaaaagtacc agaagcaatg gcgatgaaac aatatgccat ggaacaagga attcctgaaa
    24541 gagatattct tgtcgaaacc aattcgacaa ccactttgga gaatatgcgc tattcaaagg
    24601 aaatcatgga tcagcaaatg aaagggccct atcgcgcgat cttcagttcc aacaattacc
    24661 acattttcag agctggtctc tatgcacgac aagcgaaact gaaggcaaat ggcattgggg
    24721 caaaaacagc tttctattac ttgcctaacg cgtttttaag agaatacatc gccatcttga
    24781 tgatgaacaa aaaaagacat atgatcattt gcggattgct tttcgcaggt tccgcattct
    24841 tatcactgat cactttactt ttctaaaaaa ccaaggtgtg acaaaacata tgtcacacct
    24901 tgtttttttc ttttattctc ttgacgattg gcaagaatag tattcctttt ttgacggcta
    24961 cttgctgtgc agaataaata ccgctgtttc ctgaacacat aaagctgatc aagcagatca
    25021 taaagaagta aacagcagct tgtgaaccaa ataattcgat tcccatcaca aaacaggcaa
    25081 tcggtgtatt tgtcgcacca gaaaataccc cgataaaacc taatccagca agaaaaggaa
    25141 cagaaacatg gagcaaaggc gctagtactg cgccaagcgt tgcaccaatc tcaaatagtg
    25201 gtgtcacttc tcccccttgg taccccgcac ctaaagacaa gaccgtgaag aataatttcc
    25261 caataaaatc ataagcatgt gcctgtccat taaatgattc ctgcagtatc ggaagactca
    25321 acccaaggta acgttgtgtt tgcaaaatca acgctgcggc tacaactact gctccaccta
    25381 tcgtatttcg ccaaacagga tgaggaatcc attgcgcata ccgcgctttt aaaaagacga
    25441 tcgaacggct gaatacccaa ccaatcaaac caaaagcaat cccagcaaca aaaactttga
    25501 agaacagcaa catactccat tcaggaatca cacccatttg gtaatgtaga tgagaaacac
    25561 catagctttc tgtcatgaaa tttgcaaaaa gcgcagcaaa gaagctagga aagattgctt
    25621 ctgttcggac tttaccgatt gccaacactt ctaatccaaa taatgttcca gctaaaggtg
    25681 tgccaaatac agaactaaaa cccgcactga ttccactgat aaccaaaatc tcccgttctg
    25741 ctttatccaa tcggaataaa tgcgctatat tatcagctaa tgctcccccc atttgaactg
    25801 ctgttccttc acgaccaaca gatcccccaa ataaatgggt agtgatggtc ccaaacaagg
    25861 tcaatggaat gagccgcaaa gggatcttct cttctcctcc attcccttga tcgatcacta
    25921 agttattccc acgactagaa agaccgccat gatacgcata aagataagca aaaagcgcgc
    25981 cgctgactgg caatagataa aatagccaag gatgtgctag tcggatatct gtcacgaacg
    26041 tcaggctatt taagaaaaaa gcagacaagc tccccatgaa tactccgaga atcgctgtga
    26101 ccaccagcca cttcaacatg tacatcaaaa tacgcactgg actcggtaat tgtttttcca
    26161 taaaaaattc ctcctcaaat aaaaaaacgc ctactaaaga aaggggctgg ccccagactt
    26221 tagtaggcgt cattagctat cttacgttag catttaaagg cgaacaccat cacctattca
    26281 cttccattaa aagatagcat atttttctgt aaaaaacaat aaaattatcg ttctttcttt
    26341 acacgttcag caaattcata gaaaggagcc aatttcgtta actgttgatt acattgatca
    26401 ctatcatgac aaatataatt cccctttttc gtatacgtgc catcagaacc ggctttcgtt
    26461 gtagaaagaa agagcgagac attcgatgtt ttctgacaga tcgcacagat tcccttatta
    26521 atcgttggtg ataaagtacc gctgatccct tttaattttc catcttcgta ataaaccatg
    26581 aatttttttt gcgtccctgg atcattccaa ccgatgtacg tatgtgcttg caagtcgatt
    26641 tcattccaag cgggttgttt gagttttttc acttttcgga ataatttctc gatttgtggt
    26701 ttgctcggct gcataaacgg ctggacgatt tgcttcagct cctccaatgc tcgttctgct
    26761 tgcgtttttg tcagttttac atctaaaact gtcgttaaaa acgtatcgat ttctgatggt
    26821 tcgtaaccta atacatcgcg aatcttttca gctgctagag cctgaaccgt ttgtaccgtt
    26881 tttgagtcat tgacagatga gtacgcattt aataactgct ctacttctct ttttataaaa
    26941 aaatattgat atggtttcat tgtttgttcc atgattttaa agtcctttct tctaaccaaa
    27001 gtgcatactt tgtagaaaaa agtgatcttc tgcaaagtat gtgttacctg aagatcccgg
    27061 actcttttaa ataagatacg ttttgcatct tatcatcacc ccctttaatg ttcattcttc
    27121 tatgtacatg attcattcga taaataaaag taaaccgtat cttgagcaga tagtcaactg
    27181 caaacagaaa aaggactgtg acaaaagtcg tgtcaaagtc cctttctaca aacaaacggt
    27241 gttccagaag tagcttcttc aaaaaataag ccggaatttc acaaaaattt gagaagcaat
    27301 tttcgtaaat tccttcttat ttcttgaagc tgacccactt ctgtcacaac ctcaatatgg
    27361 tctattattg gttttacctg ttaaatcgag gattcttttc cgaagtaacg ttgccatctc
    27421 ttacgcatac ttgctgacat aggctgagcg gcttctttga ctgcgcagta tttgtctacg
    27481 aatgttacga tatatccttc tttgtactta ggcggtgcaa tcgttgcgcc ccacatgtgc
    27541 ttcaaaatga tatctcgctc aagatccgac aaatcggtga tcttttctgc attctttaca
    27601 gcgattcttg gatggatata cgcatgtgtg ccttcatcaa atttcgtcgt acgccaatca
    27661 tagtagaaca gatcatgcaa aagtccagca cgcgctgttg ctttagcatt gccaccccat
    27721 ttttttgcga gcagataact atagtaagaa acactgatgg aatgctccaa acgagtggaa
    27781 tgaacatgct gtgtgtaatt cgctaatttt ttcactgctt ctgtttctaa aagatcttct
    27841 acataagaca tatattcttc gtcttcacgc catttttctg tcataattat cgatctgcca
    27901 cctttttgaa tttcattttc ttctgaaatt gatctaagta taccaccagt gttcggatta
    27961 ttctagtcgc cttggataaa atagccaaag cttaatagtt ccttaatcat aaagaaaaat
    28021 gataaagaac aatccctgcc gcaaccccaa cattcaacga ttccgcattt cctttcatcg
    28081 ggatatatac gttctgatca gtcaaagaca agatttcctg acttaccccc tgaccttcgt
    28141 tccccatgat tattgcgaag ttatctgatt tttctacttt gtctaatgcg tgtgcttctt
    28201 catttaattc tgtgccatac actgtaaacc ctttgtcttt cattaaagga atcacttctg
    28261 tcaaatcttt ttgcaacaca ggcaaatgat aattgcttcc ctgcatgctg cgcagcacct
    28321 ttgtactata aatatctgcc gttcctttgc ctaataaaac accagccata tcaaatgcat
    28381 ctgccgtacg gatcatcgtc cctacatttc caggatcttg tacattatct aataacagcc
    28441 atcctcctga aaaatctggc gtgccttcag ccgttaacgc catcactgct aagattcctt
    28501 gtggtgtagg tagatccgat acagcatcca tgacctcatc cgaaactaga aaagtagaaa
    28561 tctctttgtt tgcggccagc cagtctcccc attctttcat gcctcgctgt gtcacaaaaa
    28621 gttcttttat ttctgcatca gacgacgcag cttcttcgat cagatggaac ccttccaaaa
    28681 gatattcttc cttttcttcc cgatatttct ttttatgtag tttttttaat tctttgattc
    28741 ttggattttt tgctgattgg atctctttca cattcctcac ctccccatga ttatatcatg
    28801 gaataggtgc ttgagcttgt ttcatcctaa aaaaatcggt atcattaatt tataaaatag
    28861 gaaagaaagg tgacgaacat gcgcaaagtt aaaatgaacg tccaaggacg cgtccaaggc
    28921 gtaggatttc gctacatgac caagatggtc gctgatcaac taggcgtgac tggaacggta
    28981 aaaaacgaag acgacggctc agtcacaatc gaagcaatcg gcaatgacga catcatccag
    29041 aaatttattg aagaagtcaa gaaatcaccg agcccaagtg gacgagtgca gtatgtggat
    29101 gtccaagaag acccgatgat tgaggaacga aagaaatttg atgtggtggg ataaggttgt
    29161 gaaaaagctg gtctgcatca agcattaagg acaggttgtg aaaaatagct ctccatattt
    29221 ttcaacaggc tggacttaat gccgtagatg caagcttttg aacaccgtca ataaggttgt
    29281 gagaaagtcg cttagttttg agtagtaagg agaattttgt gaaaatggct ttctacattt
    29341 tttcataaaa tttgacttaa taccgagaaa ctgacttttg aacaccgtcg ataaggttgt
    29401 ttttgaggcg ctttgcctcg agtattaagg agaaacattt tcaaaatagc ttctcatatt
    29461 ttgttaatac cgagaaactg acttttgaac accgtcgata aggttattct tgaggcgctt
    29521 tgcctcaaaa attaaggaca gcagtgaaaa agctgatcta tcacttgcag tgagttcatt
    29581 tgactccgct ttttcgggca gaaaaaaagt ttttagttta ttaaagtaag aaagaaacac
    29641 ttggaatcat tctacttttt cctagtattt ctttcttgat tttttgtctt tttttcaaaa
    29701 tttttcgcta cgtaaaagaa cgaatattta tatgaaattt ctatgaagtt gattgaattc
    29761 catgcgcttt tttagtatag ttaagtttgt gtaaaaatta tagaagagga agtattctat
    29821 gaataaatgg aaaaactggt tattgggatc cggacttgtc agtatcctgc tctttttatc
    29881 tggctgtgtg cggatggatt caaacggaaa ccctgacact tcgggaatcg tttatcgagt
    29941 actcgtccat cctatgggcc aagcgattac atatctagtt gaaaatttca attggtctta
    30001 tggctgggca gttattgcaa tgactgtgat cgtccgtatc atcatcttgc cactaggtat
    30061 tagtcaatcg aaaaaaacaa tgatccaatc tgaaaaaatg caagcgttaa aaccacaagt
    30121 tgaagcagcc caacaaaaat tgaaagctgc aacaacacgt gaagaacaaa tggcagcaca
    30181 agcagaaatg cagcaagtat accgcgaaaa cggattgagt atgaccggcg gaatcggctg
    30241 tctgcctcta ttgatccaaa tgccgatctt ctctgccttg tactttacgg cacgttatac
    30301 agaaggtatt cgggaatcat ctttctacgg catcgattta ggctcaccaa gtatggtact
    30361 tgttgtcatt gcaggggtcg cttatctgct tcaaggatac atctcaacga tcggtattcc
    30421 tgaagaacag aaaaagacga tgcgtacgat gctgatcgtc tctcctgcta tgatcgtctt
    30481 catgtcgatc agtgcgccag ccggtgttac actttactgg gtagtcggtg gtgtgttcag
    30541 ctgtctgcaa acattcatca caaacgttat gatgaaacca cgtttgaaag cacaagtggc
    30601 agaagagttg aaacaaaacc caccaaaaca agtcgtcact ccaagaaaag atgtgacaga
    30661 atcagctaaa ccagctgaca gcaaacaagc aaccaaacaa atcaaacaac caaaaaacag
    30721 tacaaacaac aaaggccgca acgcaggaaa gcagcagaag cggaaataaa aatatatgac
    30781 aaaaaactgt agacaaataa aaaaatttct ttgttctaca gtttttttgt tacaatcaaa
    30841 gaaaacgttc gcttttcgag gagggatgta taatgatgtt caaacaatca atggatagtc
    30901 gaatg
//
LOCUS       DAIGQM010000034        30847 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.034, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000034 DAIGQM010000000
VERSION     DAIGQM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.034"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(118..663)
                     /locus_tag="NOA48_001490"
     CDS             complement(118..663)
                     /locus_tag="NOA48_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0789758.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(675..1367)
                     /locus_tag="NOA48_001491"
     CDS             complement(675..1367)
                     /locus_tag="NOA48_001491"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCI0789759.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1386..1670)
                     /locus_tag="NOA48_001492"
     CDS             complement(1386..1670)
                     /locus_tag="NOA48_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789760.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1683..2246)
                     /locus_tag="NOA48_001493"
     CDS             complement(1683..2246)
                     /locus_tag="NOA48_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0789761.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2474..3136
                     /locus_tag="NOA48_001494"
     CDS             2474..3136
                     /locus_tag="NOA48_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCI0789762.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3260..4456
                     /locus_tag="NOA48_001495"
     CDS             3260..4456
                     /locus_tag="NOA48_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCI0789763.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4557..5933)
                     /locus_tag="NOA48_001496"
     CDS             complement(4557..5933)
                     /locus_tag="NOA48_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0789764.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5970..6836)
                     /locus_tag="NOA48_001497"
     CDS             complement(5970..6836)
                     /locus_tag="NOA48_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCI0789765.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6925..7950)
                     /locus_tag="NOA48_001498"
     CDS             complement(6925..7950)
                     /locus_tag="NOA48_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0789766.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7968..8642)
                     /locus_tag="NOA48_001499"
     CDS             complement(7968..8642)
                     /locus_tag="NOA48_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0789767.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIKGYIETKVG
                     QGYIVP"
     gene            complement(8826..9719)
                     /locus_tag="NOA48_001500"
     CDS             complement(8826..9719)
                     /locus_tag="NOA48_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0789768.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9793..11490)
                     /locus_tag="NOA48_001501"
     CDS             complement(9793..11490)
                     /locus_tag="NOA48_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0789769.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11483..12796)
                     /locus_tag="NOA48_001502"
     CDS             complement(11483..12796)
                     /locus_tag="NOA48_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI0789770.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12796..16833)
                     /locus_tag="NOA48_001503"
     CDS             complement(12796..16833)
                     /locus_tag="NOA48_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0789771.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FHHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16846..17304)
                     /locus_tag="NOA48_001504"
     CDS             complement(16846..17304)
                     /locus_tag="NOA48_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0789772.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17602..18120)
                     /locus_tag="NOA48_001505"
     CDS             complement(17602..18120)
                     /locus_tag="NOA48_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0789773.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18122..18739)
                     /locus_tag="NOA48_001506"
     CDS             complement(18122..18739)
                     /locus_tag="NOA48_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI0789774.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18736..19590)
                     /locus_tag="NOA48_001507"
     CDS             complement(18736..19590)
                     /locus_tag="NOA48_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0789775.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19587..20498)
                     /locus_tag="NOA48_001508"
     CDS             complement(19587..20498)
                     /locus_tag="NOA48_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0789776.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20539..21873)
                     /locus_tag="NOA48_001509"
     CDS             complement(20539..21873)
                     /locus_tag="NOA48_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0789777.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22081..22911
                     /locus_tag="NOA48_001510"
     CDS             22081..22911
                     /locus_tag="NOA48_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCI0789778.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23155..23473)
                     /locus_tag="NOA48_001511"
                     /pseudo
     CDS             complement(23155..23473)
                     /locus_tag="NOA48_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23595..23789)
                     /locus_tag="NOA48_001512"
     CDS             complement(23595..23789)
                     /locus_tag="NOA48_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789779.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24294..24479)
                     /locus_tag="NOA48_001513"
     CDS             complement(24294..24479)
                     /locus_tag="NOA48_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789780.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25329..25670)
                     /locus_tag="NOA48_001514"
     CDS             complement(25329..25670)
                     /locus_tag="NOA48_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0789781.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25670..25900)
                     /locus_tag="NOA48_001515"
     CDS             complement(25670..25900)
                     /locus_tag="NOA48_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0789782.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26187..26525
                     /locus_tag="NOA48_001516"
     CDS             26187..26525
                     /locus_tag="NOA48_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789783.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26730..26969)
                     /locus_tag="NOA48_001517"
     CDS             complement(26730..26969)
                     /locus_tag="NOA48_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0789784.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(26945..27292)
                     /locus_tag="NOA48_001518"
     CDS             complement(26945..27292)
                     /locus_tag="NOA48_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0789785.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(28024..28605)
                     /locus_tag="NOA48_001519"
     CDS             complement(28024..28605)
                     /locus_tag="NOA48_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0789786.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28788..29414)
                     /locus_tag="NOA48_001520"
     CDS             complement(28788..29414)
                     /locus_tag="NOA48_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0789787.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29436..30767)
                     /locus_tag="NOA48_001521"
     CDS             complement(29436..30767)
                     /locus_tag="NOA48_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCI0789788.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
BASE COUNT         9098 a         6595 c         5238 g         9916 t
ORIGIN      
        1 aaaaagaata agttttttta aaataacgta taaaaaagag cataaaacaa agtcgtttgt
       61 tttatgctct tcttttatta ttttgtgctt tttattttat caaatcactt tgttttttta
      121 taaaatttct gcgcctagtg tggactcaaa atgtctcaat gcccattcat gtccaacggg
      181 atcgaaactt gccacggaat ctttgaaaat atggagtttg tatcctagat tatacgcatc
      241 gactgctgta tgcaacacac agatatctgt acatacgccg gtcaaataaa tatctgtgat
      301 ctggcgttct cgcaaacgga tgtctagatc tgttccacta aaagcggaat aatgccgttt
      361 gtctatccaa taaacatttt cctcttgctc atagtcttgg tataaacttt ttaaagagcc
      421 gtacaattcc cgtccacccg ttcctatcac attatgcgga ggaaataagc ggttctccgg
      481 atgaaaggaa tcttttggat catgcgcatc aatggcaaaa acgacaaaat ccttttgatc
      541 aataaacttc tttgtatgag cagtcagctt tttttcaatt acttgtcctg ctgtcccagt
      601 agtcagcttt ccatcctctg caacaaaatc atatgtgtag tcaatcgaga tcaatgcgtt
      661 catcttagtc ctccttatac gagatgtttg acaaattcga tcaccatttc tgctgatcgt
      721 ttgcctgcgt cttcgataaa ttcgtcaaag ctttgtgtcg ccgagtgatc tgctgtgtcg
      781 ctcattgcac gtacgatcaa aaatgggata ttgaactgac gagctgtttg tccaacagcg
      841 gctccttcca tttcgcaagc taatgcttca gggaaattcg ttaagatttc tttgatttta
      901 tctggcgagt cgacaaatgt atcacctgta acgatcaatc cttcttttgc gttcaaattc
      961 gttgcttttg ctgctttaac catttcactg cgcaaatatg tgcttgcttc ataatataga
     1021 ggcattcctg gtaattgtcc tgggttgtag ccaaatcctg ttgcatctgc atcaaaataa
     1081 gctactttgt ctgatataac gatgtcacct acttgtaagc cttcaccgat tccgccagct
     1141 gaacctgtat tgatcaccat gttcacgccg tattgttgga tcaacagact tgtggtaata
     1201 gatgctaaga cttttcctat accggaacgt acgacgatca cttcgtggtt acctaatgaa
     1261 cctgaaataa ataaagcgcc tgcgcgttcc catgataatg gttcgcttag gttctctctc
     1321 aaaattttta cttcttcttc cattgcgccg ataataccga ttttcatctt tttaattcct
     1381 tctttctata taaatgcgat tgctaaaaaa accacacata acattaggat aacaataata
     1441 agagatttca tcaaaaaaga gttccatttg gtcgtctttt cccgttcgct gatccttgtt
     1501 ttcgtgattg gtttattctt tttgctttct ttacgataaa agctggcaat ctttttttct
     1561 tcttgctgat aagctgtttc tgcttttcgc tgttttttta atgactcgct tgcttgtgct
     1621 tgttgtcgct tgcgaagttc gcttcgcgta ataagcggtc ctttggccat aagccgatcc
     1681 ctctactttc ctttggtcaa tagttcccag tattgaatcg cataaatcgt ctttgcatca
     1741 caaatcaact gatctttcat cgcttgttgc gcctcttcaa gagttagatg atacaactcc
     1801 agtacttcgt cttcatcttg tgctaaagga ttctcgacct tctctacccc ttgtgcatga
     1861 taaatatgaa ggacttcatt tgcaaaacct ggtgaaagat acatcgaagt aagatggctc
     1921 agcgacttcg cacgatagcc agtttcttct tctaattctc tagctgctgt catttcggga
     1981 ttttgtcctt ctcctggatc gatttttcca gctggaatct ccaaaatcac tttttctaaa
     2041 ggttttcgaa attgtttgac aagaagcaga cgatcttgtt cgtcaaaagc aatgatcccg
     2101 acaccgccag gatgaaatac cagttctctc ttcgaagttc ctccatctgg caaacgaact
     2161 tcgtctacag caacatcaat aatttttccg ctatagattt ctttgcgact gattgttttt
     2221 tcttcaaatt gctcattgtt cagcatatct tctcctgctt tctttgtaat cataactgct
     2281 tttttttcat ttttcaattt ttctcaaaaa ctccttatta gtttaccata gataaacctt
     2341 agattttctc taaatataga aaatccttct ttagtccgat actctttcta gtagtccgta
     2401 tgctaaaata agtatgtaat cgaataacga aaagaattca atactcaacg ataaatgaca
     2461 tggagggttt attatgataa aacgaaattg gccgtggctt ctagcattgg tcttgctatt
     2521 tctctttgtc cgaaacaata gtttttcttt tgttctagga cttttattga taggtgtagt
     2581 tttagttttg tggggactct ttggttcgcg caggaaaaag ggaaaacaag aagaaattcc
     2641 tgcactgact gacgaacttg aaactcacta tgaaaaaagc ggtatgacag cgaatgaaat
     2701 ttcatttttt cgacaaacaa tgaatcaaac aaaaaatgag atcaatcaat tgcaaatgaa
     2761 tatgcagcag acagccaaac ttaaagcaat cgatctccgc catgatccag tcaaagcagc
     2821 gaaagcttta ttcaaagaat tggtgaaaga accaaaccga ctgcatgaag caagtcagtt
     2881 tctttatacg catctgccga atctagttga tttgacaaat aagtataatg agatcaatga
     2941 ccatgagatc aaaaacaaac agacctatga aaaactagaa gaaagcgcgc agatcatcga
     3001 ccagctgtca gctttaatcg cacaagatta tcaaaaattc gttgctgagg atctagatga
     3061 tatcgacgta gagatatctg ttgcgaaaca gagcttaaag cgtgataata aatatgaacc
     3121 agaacaaaag gattaactct tttgttcata aaagaagact cggaacattc agatgatgtc
     3181 tggctgtttc gagtactttt tctaaagtag agacattcat gtaagaatcg agaacagatt
     3241 caacaaggag gaatttttta tggatcataa accgactgaa acaaaagatg ttacaccagt
     3301 taacgataca cttgaagatt tattgaacaa cccgttttca actccaacag atacgctgac
     3361 cacttcacaa caagcggaga ttgatcagct ccaagagcaa cagacagctg ctcgtttaat
     3421 tgacaaacta ccggcggaac gccaagaaca agctaaacag ctagcagcaa aaatcgatgc
     3481 taatgatgca cagtctgtca tcagctacgg atcggctgcc caagcaaaat taagtgaatt
     3541 ctcacaatcg atgttgaatc atgtgcaagc acaagatatt ggtcctgtag gagattcctt
     3601 aactgaactg atgtatcgtc tccaagaagc caatcctgac gaactgcgtg ccggagaagg
     3661 gaacatcttc cagcgtgtct tcgggaaggt caaacaatcg atctatgaag tgacagcaaa
     3721 atatcaaaag attggtgcac aaattgacaa gatttcagtg aaattagata aagaaaaaga
     3781 cggtctgcta aaagataatc tgatgttaga acagctttac cagaaaaaca aagactactt
     3841 tgatgcactg aatatttata tcgctgctgg agaattgaaa atggaagaac ttcaaacaac
     3901 gatcattcca gaagcgatga aaagagcaga agaaactggc gatcagatgg atgttcagat
     3961 tgccaatgat tacacgcaat tcctagatcg tctggataaa cgtacgcatg atcttcgctt
     4021 agctagacag atcacgatcc agcaagcacc acaaatccgt ttgatccaaa acacaaatca
     4081 ggccttggct gaaaagatcc aagcatctat cgctacagcc attccgctgt ggaaaaacca
     4141 agtcgtgatc gcattgacct tgcttcgtca aaaagatgca gtaactgctc aacgccaagt
     4201 ctctgaaaca acaaacgact tattgaagaa aaattcagaa atgctgaaaa tctcagccat
     4261 cgaaacagcg aaagaaaatg aacgtggaat cgtggatatc gagacccttc aaaccactca
     4321 aaatgatttg atcgaaacaa tccaagagac attgcgtatc caaaaagaag gaaaagaaaa
     4381 acgtcgtcat gcagaagtag agcttggaca catggaagaa gatctgaaac aaaaactgtt
     4441 ggatttaacc caatagatca cctttcgctt gttactaaaa caaacgccca acaacagttt
     4501 attacaactg ttgatgggcg tttttcttat ctttcttcta acttctccat tggagtctat
     4561 ttctcattca tcttgctgtg tccatagcca tagccaaaat aaatgatcag tccaataacc
     4621 attacgatac cgaacacgat ccatgtcaca gtttgcagac gaagcatcaa tacaatacaa
     4681 gtcaagatgg agacgattgg caatagcgga acgaatggca ctttgaattc tccagctttt
     4741 ggtttgccaa acatttttct caacttcagt aagcctagac taacaagcat caaataggcg
     4801 agcgccatga tattcgttag ttccgctaat acattcaatg ggaaaaatcc ggcaaagaat
     4861 acagctgcca caccagcggc ataagtcgct tttttcggtg tacgatgctt ttgatcgatt
     4921 tctgtcataa acttaggaag taagccatcc ttgctgacag caaacagtaa acgagcaagt
     4981 gaatacatca tcgagatcgt taccgtcagt agcgttaaaa ttgcccctac agcgatcacc
     5041 gcgcccactg ttccatgtcc tacatacctc attgcaaaag ccactgggtc attgactcct
     5101 agttcagtat acggaacgat tcctgtcaag atcagcgtca cgatgatgta aaggacagta
     5161 gcaatcagta tcgaaccaat gattcctctt ggcacatctt tttgcgggtt tttgacttcc
     5221 tcggctgcca ttgcaacggc atcaaatccc aagaaagcaa aaaacacaag agctgcacca
     5281 tctagcacac cggaaaaacc aaaaggcatg aatggctgcc agttatcagg tttaacgaaa
     5341 aatattccta caatgataaa caacgcgatg ataccaaatt tgacatatac catggcatta
     5401 ttcaaacgta atgctttctt ggcttcaagc gacacgatgt aagtgacgaa tatcactacg
     5461 agcaccgcaa tcaagtcaat gtatgtacca ttttccggat tgtacccgcc agttaatgct
     5521 tgtggaagtt cggcccctaa acttttcaaa aaaccttgca tatagccaga ccatccggaa
     5581 gcaacagagg aaaccgctag taaaaattcc ccgatcaaca accaccctgt cagccaggca
     5641 gcaaattcac caaatacaac atacagatag gcatatggcc caccaatcac tggcactcgc
     5701 gaagcaaatt ctgcgaaact tagtccagac aaaatgacaa cgattgcagc taagacaaat
     5761 gaaagtgaca gtgctggacc agcattttga ttggccgcaa cccctgtcac cacaaatatt
     5821 cccgtaccga tgatcgcacc aattccaagc atgatcaaat cagacgtttt tagttctttt
     5881 ttcatctcac tcgtatgatt gagattgatc tctttcttac gaaacaaatc cattgaagtt
     5941 cctccccatt ttaggttgga aaacagcgat taaactgttt tcatataccc taaaaggata
     6001 ccacctaaaa tgactaaaag gcaaccaaca ataacataaa tgagctcttt tttcgttttt
     6061 ctttcgccaa ggatgaaaat cccacctaaa gtagagataa tgatccccat ttgtgaaagt
     6121 gagaagccaa cagctaaacc aagtgatttg actgttagaa gcatgcagat gtttcctaag
     6181 ccccataata atccacagat catgtttttc cacacaaact gatcgacttt aactttacgg
     6241 aaagcaaaga agcttgcgcc taagatcatt ccgatacttt gaggtaagat aattgacatc
     6301 gcatccaaat tcgcccagtt gacgatgatg gtatatacac cataaccaat cgtagagaag
     6361 atcaatgctc taaaaccctt accaaaatca agcattttat tatctgtatc tatttttcct
     6421 tcgtcatctt gtcgggcagt caaatacgca ccgcttacaa gaagagctaa agcaataata
     6481 ccgtatacat aatctttcgt ttgtgtccat tcatggaaga aaacggctcc cgcaatcgta
     6541 ttcaaaatta attgaaaacc agtagacaat ggtagcccta cagaaacacc catgtacttc
     6601 attccatgga actgtccatt ttgtccaaca ctccaagcta agccggataa aaatccgatc
     6661 aagaaaatcc aaggggtgat tacaggacta acaacgaaaa agacaactaa agaaaacaga
     6721 aatgcaccga tcgtcattcc tagtgtttgt tgattggcat cgccaccaat tttaccactt
     6781 actaaaccaa tactacccca tgccaacata gggactaatg ctattaaaat ttccataacc
     6841 aatctccttt tatttcacat gataagaaac ttatcagcga aaacgttaac aacacaagca
     6901 ctttttttcg tttctaacga ttttctaacg tttttcatta taaaaattta agattgggaa
     6961 aaataaagtc attgttgtcc cttttccttc agttgattca gccgtcaaat ggatacctaa
     7021 tttttcggcc agattttttg ctaaataaag tcctaatcct gttgaatgtg ttttgctaag
     7081 tcgaccattt ctcccagtaa atcccttatc aaagatccgt ttcaagtctt ccgctgggat
     7141 accgatccct gaatctttaa ctgaaaggct gactccttgc gcttcctttt ctatgctcac
     7201 aatgatgttt ccgtgatccg gcgtatattt gatggcatta ctaagcaatt ggttgaagat
     7261 aaaagcgatc catttagcat cggtcaaaac agtatgatcc tcaccaacga tctcgtagcg
     7321 aatatttttt tggataaaat aatttgcctg actgcgtatc acaggctgaa tgattccttt
     7381 tagtccatat tcttggatga ggtagtcccg cgagaaactg tcgagtcttg cataatacaa
     7441 aacttgttct acgtattcat cgatttttga taattcattt tctagtaatg tatacttttg
     7501 atcgtcaata tcgaactcga tcgaacgaac tagcaattta gaagcggaaa gtggcacttt
     7561 gatttcatgg acccatgagt caatataatc tttttggtct tgttgattac tgattgctga
     7621 ttgcattact tcttggtgtt cacggatcag ctgattgata tattcttcta ccagtttttc
     7681 ttcttctgtc ctcccaccac tcaaataatt ttgcaaaggg gaagtttttt gtatgtcggc
     7741 taattttccc caccatcttc tcttgctcaa gtaaccaccc agcagataaa aaatcagaaa
     7801 gacgccctca atcaaagcta aataagcaat tgtgctcaaa tcaactttga tgtttggcgc
     7861 cagccacatc acaaagatcg tcaatgcaat aaaaaacagc catcccaaga tcaatgtcca
     7921 ctgatctttc aaatatttaa aaaaattcat cttaaccgct catcctttca gggaacgata
     7981 tatccctgtc ctacttttgt ttcgatatat cctttgatac ctgcctgttc gatttttcgg
     8041 cgtaaccgat tgatgttgac tgtcaatgta ttgtcatcta caaatcgttc gtcatcccac
     8101 agtgctcgca gcaatttttc ccgacttaag atctttccat tgtgcttcat caaaataaat
     8161 aatagacgat attcattttt gctcaaatca atgatctctc cgttgatttc catacttccg
     8221 ttgtcaacat tcaacgtaat gccattgtgg ctcatcattt cactagataa ttctgtgtag
     8281 ttgtaagaac ggcgaagtaa tgcattgatt tttgcaatca gtacatcgat ttggaaatgt
     8341 tttgtcacaa aatcatctgc ccccatgttc atagccatga tcatatccat attcgtattc
     8401 ctgctggaga taaaaatgat cggtactttc gatacttcac gtattttttg acaccaataa
     8461 tagccatcca aaacgggaag attaatatct agtaatacaa gctgtggttc ttctctttca
     8521 aagtctgaga acacttgatt gaaatcggtc gttccaaagg tttcaaattg ccatttctca
     8581 agttcctcca tgatcaattg tcgaatgatc tcttcgtctt cgactaccat gatttttgcc
     8641 ataaaaaatc cctccatctt tcttcttgct actacaatat caaagaagcc cttgtgaaac
     8701 aagttggctt acctggaaaa tgtcatttta gcaaacgtta aaaaaaactg gaaatatgcg
     8761 atttaatcgc gtttgtctct tccaagcagc ttaaatttat tatgttattc ttaataattg
     8821 gtctattatc tgttattttt ctttcgttgt ttttgtcttt taaattttcg ataacaccaa
     8881 taaccgaaaa gcgttagcac tagcaatata cctagaagga gtataagtaa tcgataaaga
     8941 tggtattttt ttgtctgttc tatctttgaa gagacttctt ctgtaaaggg aactcgtctt
     9001 cctgtcacta gtaatcggtg agtgttcacg gtgtaaggtg tacaagtgat aagtgtgact
     9061 agatcctgct tttctctaat tgctaatgta tttgtttttg ttggaaggac aacaattttc
     9121 tcaacgactt cataagcgag catccgacca tacacttcaa gatagaatcg gtcatcttgc
     9181 tccatttctt caagatccgt aaagagtttt ttctcagcaa taccgctatg ggcggtaatc
     9241 acggaatgtg tactctctcc tccagttgga aaagaggtgc cttgcaggac tgtcgctcct
     9301 ctatctaaca aaagatcatt cgtttcatca aataaaggca agctaacatt gattttcgga
     9361 atatagatgg ctccgatcat atgttgttcg taatattctt ttcctggatt ttggacattt
     9421 ctaaccgctt gctcaaaagg atctttgact tgtcccattc ctgggattac tgatgtatga
     9481 gcaagcgtct gatttttctt ttcatgcact gctaattgtt gctcatgttt ttcttcttta
     9541 tcgcgttcaa gctgcttttg ataattctcg atccttcttt gatccaaata attgctgaga
     9601 gcatctgcta aaaatggata tgtaaaaact gcagctccgg caagaaacat cactgccata
     9661 aataattgta ataaaagact gatttgggtt tgaggtctat tacctatttt ctttttcatt
     9721 ttcttcacct tcttatttaa aaaaactgca gcaaccttta taaaaccgat tgctgcagct
     9781 tatttttgtt gcttatactt cagacttcat tttagattta cggtaccagc tgtacgctcc
     9841 aatcatcaaa cttattccga ttagtaagaa tgccaagagc ccgttcccac cagtagcagg
     9901 aagtgacccg cgtttcatat tcggtactct ttctggccct ggattttcta ctcctacgat
     9961 ctgaatttct tcattatagc ttccataaga gatgataaat tcagtaaagg ctgcctcacc
    10021 tgttggaagt acataacctt ctggcgccat ggtctctttc atttgatagg ttccataatc
    10081 taacccttga acctcaaagt atccatttcc atctgcgaca aattctgttg cttgtccgct
    10141 tgttgcccac tcaattctat ctgctcctga ttcataaaca gctaaaggcg actccccttt
    10201 ataaaatatt gcgtattcag aacggtcttc attccacaat tcgaatcttg catctttaag
    10261 caattcactg cttgatgcat catatttttc aaactttctt ccacctgttg tgactttctc
    10321 tggcggctct actccttctt cataatcaaa ttcatcattt cgtccgattt caataaccgc
    10381 tgtgttgtta tggaaatcat ccgcttctag ttctgtggaa accttcaaat tatacgtgat
    10441 cgttaaatct cctccacgtg catctgctaa tctacctaaa gtatctactt tggctactcc
    10501 attttcttct gtcaaaatcg tcacgacaaa cccgttgctt actacttcta ctatataatc
    10561 ttgtcctttt gttaaaatcg tctcgccggc tcgcacttct atttcctgat cataataagt
    10621 tagaccaact gtaggcgtat ctgtgatttt gtaatttttg ataacagcgc ttccgttttc
    10681 aaggacagaa tcgatgaaat aaggaatagg tgctgtgatc gtgtaagaag ccgtttttcc
    10741 tctttctaga tcaatataag aaatcgtttc ttgttctcca gcttcattaa taatcgttac
    10801 ttgtctaagg tcgctttcct ctacattcat ctgtttatct gcttctctga tttcgttttt
    10861 cggatacaaa tgcacatctg tattgtatgt gtctttccat gtagaaccat cccacacgcc
    10921 atccaccata tcaggcatca tcactggcat cataacaacc attggagacg cgattctgga
    10981 aatatgagct ggcgaataag tttctaagaa aagatagact ttatctctag aagaaggtgc
    11041 ttcttccgtc acttggacgg tagagaatac cgcttctcca gcttcattcg ttgtttgttt
    11101 gtcaatactt gtcagtcgat attttaaaaa ccaactttct gtgtgccgtt tttgaatcca
    11161 ttcaatcgct tcggcagaat taagaccgtc ttctcgttcc ggtgttaaag gattatctcg
    11221 aatcaaatcg taatatactt ccgttacgtc aaacaaatca aaatcgactc ctggaatatt
    11281 ttcttcacca aaatccgtag aaaccaatcc gctattcggt cgttcttccg gaacagatga
    11341 gaaacctttt ttgtgtaatg taatcgtcac ttcacttggt ttttgtgcga cttcttcggc
    11401 tttgactagt tttccgttcc cgaaaatccc tattcccgca gtaacgagta acagtacact
    11461 cattcccgtg acaatcattt ttttattcat ttttttctcc ccgttctttt tttattaata
    11521 aaacagcacc taacaataaa agaattccta gtaaagaaat caacgttctt gcttcattcg
    11581 tttgcgggaa tacggaccat tttcctgatt gacctggatt gcttggacca ctcggctctt
    11641 tcggtttgtc cgttgtttct tttacggtct cgttataaac acgtggtgtt gcggattcat
    11701 aggcagagac tggaactttc ccggattcta attcagccat ctcctgtccg ttaactacta
    11761 catattgtgg ttggcctttt gcatccaccc aaaattcagg gatgatgacc tcgattctct
    11821 tacttgcttc atccatctcg taaccttcca caccttttaa ttcttcaaaa taataggtgc
    11881 cagaaggcaa gaaacgttgt cctgtcgtaa caaggccctc tttatccgaa atgaatttgc
    11941 ttacattttt gtcattcaaa ggatcattgt ctgctggttt gatccattga tttttcaagt
    12001 cattagcagg agccatatct aaataatatt tccccccttc tatcatctga tatagagcaa
    12061 aaacagcacc ttctaatggt tttccttttt cagttgttcc tctttgacgt ccatacttga
    12121 agaagtatgg atctcttaga taaccgacat ttttaggata gatatgaatc tcttgcagtt
    12181 cctcggttga ttctgtcggg tgataaattg gcaaaatagc agcaattggg atagctgtct
    12241 gatcgatatc aacatccaat ccaacttctg gatcaatcga ttcttcgaaa atcaaataaa
    12301 ctgcatcccg atcttggttt ttcttaggtg ctttgatacg tgcaatcccg tctcctaatc
    12361 cgccaaccgt atctttccca gttgttaccg aagtccctat ttggacaagc ctttcttctg
    12421 tgattagctg acggatattg tttctgttcg tttcagcgat ttgctggacg aattctttag
    12481 gagtcatgtt ttcagcagct tttttttcat gataataatc ggtcatgtcg taaatggcaa
    12541 atgtcgctcc atttagtggc accgtctgtg aaatgatatc tgctgtttcc cctgcttcct
    12601 cagagatagc caagccatca ttttcatggt attcaaattg atcgttataa tcgatatctc
    12661 gaatcatccg tttatgcaac acgaattcca cgacatcttc ccctgattct tctgccgaca
    12721 tcgcatgtgg aagaaggact gctgcaagcg gtagtaaaac aagtaattga agcatcaaac
    12781 acaacagctt tttcattacc ttgctccctc ctttttagat tgtctgacaa acaaaccata
    12841 ggctgctcct gcaagcgcca tgaagaatgc agcaagcagg atatagaata atcgtccgga
    12901 tcctcctgta gcaggcaacg gattttcagg atcgttcccg acactaagct gtaatctgat
    12961 tcgatttgtc tccaaaagtt catattctaa ctcttgctgt agatcaggcg tctctgcttc
    13021 ttcgtttgga taatacgaaa tctcaacttt tagtgtaccc gcttcttttc ctggaactac
    13081 ccgatcattt tctatgtcag gttcttctcg ataactaatt tctaaaataa agtaacctgg
    13141 aagttttcta tagctgtcag gtgacttcac ttccttgatc cgatagaccc cttccaacaa
    13201 gtctgaagca ttgaataggg aagaatcgtt tggatctggt gccaagcctc cctcgatgat
    13261 ttcatactct cctgcactat tttgtttctc aattgaaaat tctgcgcctt caagacgtcg
    13321 gctattcata ctgtcaattt tcaaaagttc caaatcgatt ggcgctagtt catcttctaa
    13381 ggttacttgt agtacaccat cgatgatttc atagccttcc ggcaagggag cagtttcgtc
    13441 ttcgatgacc gtatcttcaa tgataaactt accttcttca ttcagtgcaa actggaacac
    13501 ttgatcagat agccgatacc catttggtgc gacagattcc gagacctcat attcaccaat
    13561 agacagatgc agaggttggt cgtaatttaa atcgacatac ttttctactc ctacggcacg
    13621 agaatagaag tatccgatcc caggcaaacg tttcgattct tctggttcta acggattacc
    13681 agtgtatgct cgatacagcg ggaaggaaga atcccccact ttcctgatat cgaaacctgc
    13741 accatctaat gtatggcctt catggtctaa ttttctaact cggatctccc gataatcaaa
    13801 cgtattgtaa gcagtgaatg ctacccataa acgatcctct tcatctgttg tatacgtgag
    13861 atattgccaa ttttcttcac ctgtttgctt gagttggata gtccctatag cattatcgta
    13921 aagtcgcaag atccatgtgt cattttcatc aggttctttg aaaccttctg ggttctggct
    13981 ctcaatgatt ttgtattctg catagttggt agtttcttca ctatccttat aaacaaatga
    14041 atctggctct ccgattggat gaataacttt ctcaccatcc acgattacat atttcccgtc
    14101 ttcatctact gaatagaacg tgagtctccc tttctcttcc tctacttcgt tcacaccaga
    14161 aagccctttc gctactggat atccgatttc cagtccgtta ccatctgttt cataaagttc
    14221 aaactctgcg ccattgattg gcatattact gccttcaatt agtttattga tattcatgtg
    14281 gattggcttg aattcatttc gcatttccag tttgacatac aactcatcat actctgtgcc
    14341 ttctatgtta ggctcttgta caacagaaag cttgtgatat tctccttcat aataggaatt
    14401 cggatcttta ccttccggtc cgccgactct cgaaccagat gtatattcat ctacaagctc
    14461 gtagtgacct aacatctcat cttcgttggc tgcatatttt ttgatttgga attgatacgt
    14521 ctcatctact aactgataac gtggtggtcc agcgatctct ctgatccaaa atatgtcgct
    14581 gactgctcca gtttcatctc ctaaaatcgg catcttcgtt tcaaagatcg ctattccgtc
    14641 cgtggtagtt ttacttgttt cgattggttc ggcttcccca ctctctggat tttggtcata
    14701 taatgcaaat tcgactccag ccaacggctc gccattttga cccttcttgc tgacttggaa
    14761 attacggcct ttatgttcgt aacgaatgga agaagatggg aaatacatcc gtccagtagt
    14821 gatatcattc tcataatcct ccaggttctg aatataggcc atattgttca ctgtgcaaaa
    14881 atttccgtct tgagctcccg catcaagttt tacttggtac ttgatcctga ccatttcccc
    14941 ttcacctaaa gaaatcggag aaaatttata agcttggttt tcccgtccga catacgttgt
    15001 cggagtcgcc actacttctg gtggggcttg tccatgacgt tcttcatccc atatttctgg
    15061 ctcttggtac ttcatgccgt tttctcctgg atctagatgg taaaactgaa tatctgccga
    15121 tctgccagct ccaaatggtg agacattaaa accagtttca tcataaagtg tggcttgctg
    15181 gatcgttctc ttgaaggtag aagagatatc ctccaaggct gtaacaatgt cattcttgtt
    15241 gttcgcattg taatatcgcg gtgttacgcc atcttcttct aaatcagcaa tatttttcaa
    15301 tacatttcgt ccaatagcat ctagtcgttg tctcccgcta acgtttccat cgattcctaa
    15361 accaatggag aagatacttg gcgggttctc ttgatacttg tttttcagcc aatgatgata
    15421 agcaactgtg ttgatcgcag atgacttttc ttgcgaagta ggactgccat tcgtattgtt
    15481 attagaagaa ccatcaccaa cccagtgagt cgctttatta tctccttctt ttacctctcc
    15541 ataacgatag tgtacattta cttcatcttc tggacggtta aagtcagatg cataggtaac
    15601 tggatgagta aaccctgcat tagaagtatt cccagaaaac tcctcaaaat ttctgaacaa
    15661 aacgtcatta tcttcagcaa tcttatcttc catcacagtc cagttgctcc aagctccatt
    15721 agtgctcgta cgataacttg actgaatcgg tgcataactg aaggtcggtg tcccatctcc
    15781 cacaacgatt aggatttttt ctggatttct attttctccg ccattgtctt tatacaatgt
    15841 ttcatagcca tttttaagcc ctagtgtaag cggagttcct ccgattggtg tacgatttaa
    15901 tgctgtattc tcacttcccg tcaaacgatt gatatcattt gtcaatggaa agatgtccga
    15961 actgatttgc tcatggttat tgatagctgt actattatgg tgaaaattca ccataccgat
    16021 tcgaatatcc agactcgggt cagagagcag atctttactc atttcgttta ctgcctcaat
    16081 caacgcagca tttttagttt gactattggt cccagcggtt aattcactca tactcgctga
    16141 cttatctaga acaaaaacga tatcgattgg actgatttcc tttttctcgc ccccgatgac
    16201 atctagatag acattgtaaa gggttgttgc atcttcagga tgtagatcag atgctgtgct
    16261 gcttggcaga acaggttcta cccatttttt gatgtacgcc ccgttataat ccaagtaact
    16321 gttttcaaaa ttccgttcat ttccccaaag ctgaacggtt tgagctggaa cgtttctatc
    16381 ttcttcgcct gcagttgatc cattattagt agcatagtcg taatttcgcc agttcgctcc
    16441 cccgtttgta taatcactat catcgatcaa gttctctccg tcatatggcg agcctttgtc
    16501 tccttgatag cgttcattgc tttgtgtcca atttcctaac acttttgtat agtcattcgt
    16561 tgtaaacttc gggtagcgat gctgttcgtt ttcaacttct ccgctaggat agatatattc
    16621 ataggggtct tgcgtagctg ttggcccaag acgctccaaa ataccgttga ataactggcg
    16681 ttgaatgcgc tggagtgctt gaccgctggg tacgattggt tcgtccagct tttccatctc
    16741 attttcttcg ctacgttgaa tttcagcgga atcttctgta tcagtttcat tttcttgtaa
    16801 ttcttggtta tctattcttt catcaaccac cacttgaaga ggtagttacc cttcgttcac
    16861 atcggggatc ttttctgttt caaaaatcaa tgtgccggtt tctgcttctt ttgaataaac
    16921 ttttccgaca taccattctt gaccatcgat cgtctcgact tttaggtctt ctccatcttc
    16981 atcataggag gatagacctg ttccacgaac gttttttacg gtaccaatcc cggcggctgc
    17041 cgcatcgatt gctaaacgta ttctaccttc attggcactt tccttttttt caaaagccag
    17101 atgccattca agggtttctt ctttttcaat atacttccct tcaatttttg catagtcctc
    17161 atctaagaat acctcatcct cctttgtttc tgttgactca gcagctacat ccagggtcgt
    17221 catatgatag actgactgga aatatggtcc aaatagcaaa ctgacagtta ctaactgcaa
    17281 aagcttcaat tttaaccctt tcacatcctt atactccttt caaaaatatt tgtcttcttt
    17341 cacaacaatc aacaaaacaa tgcccatcta attataattt aatttaattt taattttaaa
    17401 tcaaatgata tcctttttag ttaaaaaaca ccaattatac aacatttatt attaaaatta
    17461 aattataaaa ttttataacg ttctcattta acaaaactta agttattaag acaaatgaat
    17521 aaacaactac gctttcctcg aaacaaaaaa ataaagcaca aatgcgcatt tacgcactca
    17581 tgctttattc gtacaattaa ttcagataac ggcagcgcat aggatgccaa taacacttcc
    17641 taaaatagct cctcctaaaa tgtcagtagg ataatgtaaa agtaaaaaaa tcctcgaata
    17701 agcgatcaaa caagcaaata aaaaggctaa tattcctgca actggactta attcgaacaa
    17761 cgcagctact gataaaaagg ctagcgctgt atgtcctgaa ggaaaagaag aagtcttcgg
    17821 tttacttgtg taaaggacaa gccgacgatt tttttcataa ggtcttttcc gtcttgtcgt
    17881 ttttttgata aaaagcaaac caacaaaaaa atagatcaaa ctgccgataa gaatggctag
    17941 accatattct ctagtatcag gtatcaagac taaaacagca gcaaggagca accaaataaa
    18001 accaccatta gagatattac tgataaattt caaaaaattg atttttcgac tatccgtttt
    18061 ccgttgcttg gcgaacttgt tgataatact atcatcgatt ttagcaatca aacgcaacat
    18121 gttattcctc ctttttaaga accttttctt gcgtacgatg gataaaaagc aggacttgaa
    18181 aataaaacaa gaaactgaaa cctaataaag caaaatagat tggtcctgca aaccagaatg
    18241 cgacaagaag gatcaacgtg cctgccaaat agaaaagcgc gcttttgaaa tcattaaaaa
    18301 acaagaaaaa tgcagtaatc caagaagctt ctttttgttc cagttgaagc aagattttgt
    18361 aactaaagag aagcgcgctt aatagaagca aaaacaacgt agtatacatc aatgtatagc
    18421 caattccccc accccaatag cggaaaatct gataatcgat caatagaaga agaaaataaa
    18481 cacttgctaa actatcttgc tttccataaa gagagaagtt ctcacgaaac tttttccaga
    18541 atagtgaacc gagctttttc tcttcatttt ttttgtaatg ataaatcata tacagaactg
    18601 ttcgacttgc agttcctaat gtgaaaacag gcaagacgca caggaaccat agtagctgta
    18661 aatggataag acgtggaatc cattcaatga tttctaagaa ataatcattg gcttttttac
    18721 caatcgatcg attcatcatc cttttgaacc tcctgtcaaa tccatccctt caatgaaata
    18781 acgttgtgca aaaaagaaca gcaaaatcgt cgggatcaag acaagtgttg ctcctgccat
    18841 cagataattc cattgtgtcg ttgcttggtt ctgaaaaact tgcaagccaa tctgtaacgt
    18901 gtatttttct tgatcttgga tatataacag aggacctaag aaatcattcc aagctgcgtt
    18961 gaaggaattg atcgcaatgg taatcaaggc aggtttcgtc aatggaagca tcaaatgact
    19021 ccaaatatac aaatgattcg ctccgtcgat ttcagcagct tcgatcaatt cattattgat
    19081 cgataagtaa aattgacgca tcagaaatat attgaacgca ttgccgaaga acgatggaac
    19141 gatcaggggc aaataagtac ctacccagcc gatcttggag aataatacat attgagggat
    19201 catcgttaca aaccccggga tcatcatcgt agaaagaacc aaagcaaaca tcagcttttt
    19261 cccaggaaaa tcaagcttcg caaatccata agcaataaaa gaatttgaaa ggacattacc
    19321 gatcactact agcacagtga tgaataatgt atttcttgca tagcgccaaa aaggaaaggc
    19381 ggcaatcgta tccagatagt tttcccatac gattttttct gggaaaaagg tcggaggata
    19441 acgaacgatt tcttccattg gtttcaatga agtaaacacc atccaaagca atggaatgat
    19501 caaaatgatt cctattactg tcatgaggac ataacttagt attttttttg tttgccgatt
    19561 cacactggtc tttttgaaat aatccatcat ttgccgtcac ctccagaata atagacccac
    19621 ttaggtgcaa gcttcaaatt gacaaacgtc agaaccaaca cgatcagaaa caggatcatt
    19681 gacatagcca tcgcataacc catatcaaaa gctacgaacg ccttgttcca catatgcaga
    19741 ttataaaaaa gcaaagaatt tgcaggtccg cctgttccat ttttcgtcat gacataagct
    19801 tcttgaaaaa tttggaaaga accgatcgta gaggtgatca catcgtaaaa aataatagga
    19861 gtgattaatg gcaaagtaat acttttgaac tttccccaaa cgcctgctcc atcgatttct
    19921 gctgattcat ataaagatct aggaacattt tgtaatgtag ctaagtaaag tagcattgct
    19981 cctccagaac tccatatttt catcaaaatc aacgcaggtt tcgtccattg tggatcaaac
    20041 agccaagctg gtccagggat atggaaccag cccagaaatg tgttgatcaa tcctgcagat
    20101 ggagaaagca gctgcatcca taagatgtag actgctactc ctgataagac tgccggtaaa
    20161 tagaaagctg tacggaatac actgattcct ttgatttttt gattgagtac tgtggctaaa
    20221 aacacactga aaatcgtcgt cagcggtaca ttgaagatga cgaaataaac ggtgttgtat
    20281 aacgatttcc aaaataaatc atcgtgaacg aacattcttt tgaaatttgc tagaccaatg
    20341 aaattcatct tggatgtcaa attataatcg gtgaaactac caataactga aaaaagcata
    20401 ggccctagca taaataccaa gaacccgata ataaaaggcg agataaataa ataggcccat
    20461 cttgcttctt ttttctttcg gatagataaa cgcttcaaat tttcttgcct cctctgtacc
    20521 tagacagtca aaaatggatt attgattttg cttgactaag ttttctactg ctttttgtgc
    20581 atctgccaat ccttcttttg gtgattttgt tcctaaaaga atctggtcaa tctgttcatt
    20641 cactaatgtc gtgtaatccg gagcatctaa aggaactggt gtgatcaccg tatttttaaa
    20701 gttttcgtcc gccatttgat agatcatttt tcctttatcc gttaggttgt cattattcac
    20761 taaattctca ttggctgtct tgctcgccat gatatcaaaa cttttttcgc cgaatttttc
    20821 ttgtacttct ggagaagaaa gatatttgat gaattcataa gaggcctcag gatcttttgc
    20881 tccgtatggt acttccaaga cgaatccgcc accccacgac caatggcctg aaccttcttc
    20941 tttttctggg agctgcatca cgccaaaatc aaaatcatcc ggtgcatttt ccatcaaact
    21001 agagtaataa ttgatatttt gggcacgcat ggctactaat ccggaaataa atggatcaga
    21061 tacaccagac ccaaattcgg cttctaattt attgatcgta tttttcccat aataatcttg
    21121 ccagtcttgg atccactcca aggcttccac tttattttta gtatcaatct tgactttttc
    21181 atctttgtca aaccaactag tcccgttatc tgcgtttagc gcccatacat cagcccctaa
    21241 attccataat ggataaaaac cgatgcgtgt aaattctttt ccttcttttt tatctagttt
    21301 acgtgctgtt tcttctaatt catcccaagt tgtcggtaga tcttgttcac tgattccagc
    21361 ttctttaaat aactttttat tataaaaaat gacttgtgta tctgtattga atgggatcgc
    21421 ataaggatca ccttcatatt ctactgtatc ccaaagctgc ggataaaaat ccttagaagt
    21481 gtctttttct acatatttgg agagattagt tgcttgctgt gcttctgctc tttgggcaac
    21541 ggaatttatg tcctgtacaa taacatcggg tgcatttcca gctgttattg cagataaaga
    21601 tttagtccag atgtcacccc atggctgata cttataattt acatggatct cgttttgtga
    21661 ttgattgaaa tcctcaatga tttcttcgat agcttctttt cgtgcaccgg atccccaaaa
    21721 ggaccagaaa tcaatatttt ttcttccatc acttgttttt tcagaagaat ttgctgcact
    21781 tgaactggca tcgcttgcat tacttgatcc gcatcctcct aataaaaaca atgctgaact
    21841 tgccagcaac cctgtaaaca ataatttttt catattttac ctccaaattt taatgtaacc
    21901 gatgccggtt ttaatataac gatatcattt tgttctgaaa ataacaattt ataaggtatg
    21961 attctaaaaa aattattaat gataccaata ctttatataa ttcgcgagcg ctttctttga
    22021 attttttaat ctttcgtagc agaatgagaa tgtattaaaa atagattagg aggaattttg
    22081 atgtttagac accagaaaga attgcagttt gaagcaaaac cagatcgtcc gaatccatta
    22141 atcgcgaaat atctgcagga gctgatcggc ggccaatatg gcgagatgag tgtagctatg
    22201 cagtacctgt tccaaggctg gagctgccga ggagaagaaa aatataaaga tatgctgatg
    22261 gacattgcaa cagaagaaat cggccacgtg gaaatgttgg cgacaatggt tgctcgttta
    22321 ttagagggtg cgcctgttga agatcaagaa gcagcgatgc aaaaagatcc aacaatcggt
    22381 gccattatct ctggaatgaa tccacagcac gcgatcgtag ctggcttagg acctcgtcct
    22441 gctgacagcg tgggcaatcc atggagcggt gcctatatca ttgcgagtgg caacttgtta
    22501 gcagacttta gagctaattt aaatgccgaa tcacaaggaa gacttcaagt agcacgtatt
    22561 tacgaaatga tcgatgatcg tggcgtaaaa gatatgctgt ctgttctcct tgcaagagat
    22621 agctatcatc aaaatctatg ggaatgtgca gtgaaagaat tagaagaaaa agaaggttca
    22681 atcttagtcc caagtacttt cccgcgtgac aaagaacgaa aagacattgc ttatgacttc
    22741 tataacttct cagagggaga ccaaagtagt gaaggttctt gggctagtgg caaagcactg
    22801 gatggcgaag gcgaatatca atggttgaaa gaacctaaga tcgaaggcgc tgcaccaaaa
    22861 ttagaaccag taacaccaaa aatgtatggg acacctccat tcaagaaata aatatctacc
    22921 cgtagaaaca cccgtttttt gttccacacg ctttgtgagc aaaactgact aaagtcatta
    22981 atcataacca cccttcaaaa gggtggtttt ctctagagct ataagctcaa atcaccggcc
    23041 agcgcctaaa gacgctggct ttcatatttt atgttcaagc catattgcct ttgccagttt
    23101 tgcccacctc ttaaaaggtt tatgtactac tccttagccc ttaaaaggat cgtcttactc
    23161 tcgtacactc agcttatcta acgcactatc atgtttttct tgttcttgaa tgtacttttt
    23221 gatggtcgct tcattttgtc ctacttttgt cacatagtat ccttccaccc aaaagtgtcg
    23281 atacccaaat ttatatttta gatttgcaca atctcttgat gatctcctga atattggctc
    23341 gatattgatt ataaattatt tttcttctat actttggtgt gaatacaatg tggtatttac
    23401 acatctactt tgtacgggct aaactatttc cctttattgc tccacccgca tagcaagtgg
    23461 ttttgtattt caatcgctcg gcgcgctcaa ttaggtctaa agacaataaa tctaaaaacc
    23521 cgctgcttca ctgacagaaa caacgggttt tcagaaaaaa atgaaatgaa aaagatctct
    23581 tacggcaatc tattttattt ttttgatttt ttataaatgg aaaatgcttc aagaagtcca
    23641 agaaataaag ccgtataaaa acaagaacct atgaaatctt tatttattag atattcaaca
    23701 gaaatcccga taacactagc caacaatata tttatcagaa gtgtaaaata aggatgcttt
    23761 ttatagaata gaactagtgt tgttttcata gactctcctt tcttcatatt tccaattaat
    23821 cacaaattca cggcattact agaaaaatta aaggggcgca gaagtggaaa aatactcttc
    23881 gactttccct acaaaccagg ccatcttgtg tttaataact ataccaaatc taaggtacct
    23941 ctaaatctaa attccatttg tggcggtgac ctccaatttt taactcttct atctcccatc
    24001 cagtatacat aaccttgata cttcgaccac ttatatatcg aacacacaaa tacctatcca
    24061 ttgcaggagt actacctaac ttagttgcta cttgcatcta aataacagct gaaaagatag
    24121 gacttactct tagtaaagta tctgaactat taatttttaa actatcattt ttatcctcaa
    24181 ctacatgcac atctgttgca acttcacttt ctgtctcatc cagataaatg attaaggaat
    24241 cgggaattgc aatatcttca gctgacgctg gaatagttga gctaaattag tcatcatatc
    24301 tttattataa aataaccaac agcaaaaaat acaatgaaaa acaaacttgg aactaatgta
    24361 tcattaataa atgttgaaaa attcagcaac tcattactgt atgattttag cagcccaacc
    24421 aacatatacc ctataaaagc taataagatg gttaggaatc ctttagaatt tttactcatt
    24481 catagacact tccttaaata acttttatta tagaaggtat tgtaaataat aatattgaca
    24541 aaaagtgact caaaataaaa aaaaccttac attatactgg aatgaactgt attgatagtg
    24601 tacctaaaag ctctactgac ataagatcgt gtaatcggta aagtaatttt attaattata
    24661 cgggatgtaa tcaattagag aataaactaa tcataaaagg tacttttaca ttcataattg
    24721 tcgctttgag attctacttt ggttcactat ctgacccaat tgcacatttt cgatcattac
    24781 aagtattggt gtcgttagaa caactaaata aaaactagcg gtagattttt cagaatctat
    24841 gctaatttct gtatggatgt tccagtgatg gcaaatttct cttttcattg tttttcttgt
    24901 cgcatgatat gcctttttgt gttattcagt taaactatag aaattctttc ctagacagat
    24961 cttgatccca aattttacgt ttttgagcat cgatatagtt taaaatgaca ttactcatat
    25021 ctaaagagtt tagatttttt aggactaaaa ctgtcagttg ttctttttct tctttctgtt
    25081 aaagtattgt cgcgactttt cgtatacgtt aagatatgtc gtgaaaaaac aagttttgtg
    25141 acacaaaaaa acgaatgact tgaggaaatc acctcaatca ttcgtttaaa atgctatata
    25201 ttctttagtt taagatacgg aaattaatgc catcgaccac actagtagaa tgaacgacat
    25261 ttacttggcc tttttttaat ttcgttatgt ttagcatata aaaatattat agagtttact
    25321 tacaatgctt aaaacatata ctgtataatc tgatcaattt tagccatgtc ttgcaatggt
    25381 aagttttcta tttttttgag ttttcgttcc ttaaaatcaa gagattttaa ttgtgtaata
    25441 attacttgtc cttttatatc tagctcttca ggtaatgagt aacgtgtcgg taaattcttt
    25501 atagtggaag taattggaca tatgaccgaa aacattgttt tacggttaaa ttcataacga
    25561 gagacgacta gtcctggtcg tcttttttga atttcttttc ctacggaggg atcaaaatca
    25621 atccatacaa tatcaccttt tttaggaata taaattcttt cttctgacac tataaaattt
    25681 ctctcccttc aggagttaaa tcttcccatt cgtctttctc ataatactcg gcctcttccc
    25741 caccactaaa tggatcttca atttttggaa ctaacgtaat tgttccatca tcagaataca
    25801 caacgatata ttcttggttt tctgaaggtt tctttccgtt atcagaaggt aaagttacca
    25861 ctacagaact tccttgtaat ctagattttg taacaagcat tatcatcact cccttaataa
    25921 aagtatacta tataacacta agtaacgcaa aattcccctt tgtaaactat ctagaaaatt
    25981 gttttgttta aagtatatct tattggatat aaatagaaat aaattgtagc cagttcattt
    26041 tttctttaac taaaaaaata atccaagaaa cattgaacct atggatccaa aagctaccca
    26101 aatactatag ctaacccccc gctaccttca attttgcaga taaaacgctt tgggagaaaa
    26161 tttcaaagac aacaggccat cctatcatgc ccgattataa acaaaaagct ggctattcct
    26221 tttgctctga caaatttcaa ttgggaaagt tcacgaaact agcaggtgaa gaagtttcaa
    26281 ctgttcggat caaagaatgc ccgcttcaaa tagaaacatt ggttcaacga atttcaacta
    26341 gacaagactt tgctattgta gaacgtgaga tcgtagctat ttttgtagaa gaagggattt
    26401 tacatgatcc aactcatatc aatgtggata aatggcaacc tcttatctat aaattcagag
    26461 aatatacaac tgccaaccag tcgttaactt tgaattttag attccaagaa ttcaaagagt
    26521 cataatgata aacatcgtta ggtataaata aaaaagactc gcagcacgag taaaaaacaa
    26581 atagaagcta tacattagaa aggtcgactg tgaccctata gatgcagtat atgcagctta
    26641 tgagcatttc ttctgttctc tttgtttttg ggatctgtgc tgaagtcttt ttcgtttttt
    26701 gccgctcttt ctttgaaaaa tcgattatgt tataccttct ccattactaa ttcaggcatc
    26761 tgctgagtaa tgatttttcg cgcaaaagaa atatctgtta cccaaggttc gatttgttct
    26821 tcagtcaaga caagcggcat tcggtcatgg attggtgcga ctgtgcggtt aggttcagta
    26881 gtcattatga ttgattctgc cattttttca tcctgatggc tacgataaaa accgccaata
    26941 tacactattt tttccttatt tgaaaacata aatttgtctt tttcttcatt ccactcattg
    27001 ggaaaacaca acgattttgc aaaaatggtt gatgaaaggt ctttttttct tctactgtct
    27061 ctgcacgggc attaatcatc aattgtcctt ttttaaatcc ggtaaatccc cacttcatga
    27121 tttccggagt gaggatgttt tcttcctctt ttcttaacgt cacaacaaga tttgacggaa
    27181 aaacttctcc agctgctaat tctgctgcct gcttcggttg tttcgtctgg gcttctcgat
    27241 aataattctg aaggagctct gactctagat caaaaaaata acgaccacac atcctaatcc
    27301 ctcccaatct ttttttctat catacactgc aacaagaagt tcgcaccaac aaaacgcttt
    27361 caatttttgt agaactaaaa aagttgtgac aagtgacaaa ctctccagtg aatggtattc
    27421 tcctgccaac tcctcggtca caagtcacaa tattcaacaa acatgagaag ctgctttttg
    27481 aaattgttcc ttgtgactcg gagtgaaacg gcaggcttac gacctctggg taaacggtgt
    27541 tcaaaagcca gtttctcggt attaagccaa atttatgcaa aaatgtagaa agctattttc
    27601 acaaaatttt tcttaatact cgaaactaag cgactttttc acaacctctt ccttaaacgg
    27661 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat gagcagctat
    27721 ttttatttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc tctccactaa
    27781 acggtgttca atcagctaac cttcggtatt agctcaaaaa acggcaaaat atgaggaact
    27841 attttgccgt ttgtttctct aatactcagg tcaaagcgct gatttcacaa cctctaatac
    27901 acggtgttcc agaagtagct tcttcgaaaa ataagccgaa atttcacaaa aatttgagaa
    27961 gcaattttcg taaattcctt cttatttctt gaagctgacc acttctgtca caacctctaa
    28021 ttattaaaga accttttgcg aagttaacaa tctttctttg atcaattgaa aattctgcct
    28081 aagtagtgat agatcctgtg tgactttcaa caataagata cttccctgga tttcagcaat
    28141 caacgctttg gcttgacggt ctgcttcttc atcggacagt ttttcttcag aaagtgccag
    28201 gatattttgt ttcgtatact tgacccattg attgactaat tctagtagca acagacggta
    28261 ttcttcatcc actgtactca actcaataat caaattacct acaggacagc catgataagt
    28321 gatctgtgtc tcatgatcag cgaaaatcca gtccaacatt tcttctaatg cttcttctgg
    28381 ctgttttcca gcatttaaga tgtcttcgaa caattctgtc tgccatacgt ccatatgcgc
    28441 atggatcacc gctagacaaa cttctttttt tgaagaaaag taataataaa attgaccttt
    28501 tcctgtatca gaagctgcta gaatatctcg gattgacgtt tcatgatagc cttttttata
    28561 aataagatct ttggtcgctt ccaagatctt ttcctttgtt ttcaatgata ttctcctttt
    28621 tcatttctca tagtcctata ttatacagta aattcatcat tttttcttct taatcgttta
    28681 aaaaagactg tgccaaatta tctgacacag ccctcactat aaaactgttc tcatatagct
    28741 agatgttcat tgattcaaga actgcgagga caaaagcaat tcctatctta tgatagttgc
    28801 tctaatactt cctctgttgt catcacttga tctgcaataa agccaaagtt cgtcaacgct
    28861 gcatccattg cttcttggcc aggagcacca attgcatctg tcgctaccac aacattgaat
    28921 ccactctcta ccaattcacg catatgggaa tcgctacaca agtttccgtt cattccacca
    28981 agaattactg tgtcgattcc attttttctc aattggagcg ccaaatcatt gctttctggt
    29041 ccaaagattt tatgaggaga gctgatgatc gtattttcat ccaaataagg tttcaattct
    29101 tcgataaaat cggctcctga accttcttcc actgattcat attgactttt tctagcaaac
    29161 atctgctgct caagcatcat atgttctcct gcaccgccaa attgccattt atggtcatgt
    29221 gggtaaaaat aatgaggaga aataaagagt ttgtatcctt tttcttttgc ttgttttacc
    29281 atttcaatca tattttcgat cgtattgtat ttttctaaga tatcttttgt caaaccaaag
    29341 ccaccgcctg ctggtttcaa gaactcgact tgcgggtcag tgagaactac tgctgtattt
    29401 ttattattga acatggtgga ttctccattc gttatttatt ttaatacatc atttagagct
    29461 tcactcattg tcggatgaga atagatttga tctctcaata acgtataagg aagttttcca
    29521 ttcatagcta gcgaaatcaa gttgatgact tcatgagaat cttccgcata gatacttgcc
    29581 cctagaatca agtcagtttc agggtcgact aaaactttga atacaccttt aggatcttct
    29641 aatacttgtg ctttagggac accgcttgtc atatacttga ataatttgta attgacgcct
    29701 tgtgctttgg cttgtttttc tgttaaacct acattggata aagtcggagt gataaataca
    29761 ctgtaaggca cagctttccg gttattcgtt gttcgtttat tctcgccctt caactgatcc
    29821 ataatgattc gataatcatc tagagagata taagtgaact gcaatccgcc tttgacgtct
    29881 ccaatcgccc aaatgttgtc tgcatctgta cgaaggtatt catccacagc gattgctccg
    29941 cgatctgtta gtttaacatc tgtattttct aatccaagtg atgctgtact tggttttctt
    30001 ccagttgcag ccaaaacttt tgacgcttgg attgttactt cttggccatc ttctgtaaag
    30061 gtgacggcag ctgttgattc ttggtctgct acttgatcta cagatacacc tagatggaat
    30121 tcgattcccg catttgtcat gtcttctaaa atcatttgcg cgatatcttc atcttcacgt
    30181 ggaagaaatt cagaatgggc atcaagaacg acaactttag atccgtattc attgaacatt
    30241 gatgcaaatt ccaagccaat atatccagcc ccgatgatca ctaatttttc cggtaattgt
    30301 tcctgatcca tcgcttgcgt agaatcaatc aagtagcgac ttgtattcaa tcctttgatt
    30361 ggtaaaatga ttggttcaga accagtattg atgaaaatcc gttcgccttc aacaatcact
    30421 ttttcaccat tattcgtcac ttcgatttga tggttagaaa gaaaacgtgc tgtaccgtcc
    30481 atcactgtcc cagttgcctc atcgctgatc atatgataat ttttggcgcg aagcatgccc
    30541 gtcaattttt ctttccgagc aacagcctct gtaaagtcga ttcctctttc tccattgaaa
    30601 atcaatgatt tagaaggaat acagccgatg ttgatacatg ttccgccata catacgtgtt
    30661 gacttttcaa cgactaaaac cgattcacct tttgaagcta acgccttcgc taaagtctta
    30721 ccgccctttc caaaaccgat cacaatattt tgatattttt ccatcatttt tccctcgctt
    30781 cttttttacc taccgattgg tacaaaaata tgataaccga taattgtcta ttctccaaat
    30841 catctgc
//
LOCUS       DAIGQM010000035        29682 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.035, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000035 DAIGQM010000000
VERSION     DAIGQM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.035"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..116
                     /locus_tag="NOA48_001522"
     CDS             <1..116
                     /locus_tag="NOA48_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0789789.1"
                     /translation="LSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            308..928
                     /locus_tag="NOA48_001523"
     CDS             308..928
                     /locus_tag="NOA48_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCI0789790.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(1020..2186)
                     /locus_tag="NOA48_001524"
     CDS             complement(1020..2186)
                     /locus_tag="NOA48_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0789791.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(2198..2551)
                     /locus_tag="NOA48_001525"
     CDS             complement(2198..2551)
                     /locus_tag="NOA48_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0789792.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            2679..3701
                     /locus_tag="NOA48_001526"
     CDS             2679..3701
                     /locus_tag="NOA48_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCI0789793.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            3720..3881
                     /locus_tag="NOA48_001527"
     CDS             3720..3881
                     /locus_tag="NOA48_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789794.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(4140..4574)
                     /locus_tag="NOA48_001528"
     CDS             complement(4140..4574)
                     /locus_tag="NOA48_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789795.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(4684..6543)
                     /locus_tag="NOA48_001529"
     CDS             complement(4684..6543)
                     /locus_tag="NOA48_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0789796.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(6661..7820)
                     /locus_tag="NOA48_001530"
                     /pseudo
     CDS             complement(6661..7820)
                     /locus_tag="NOA48_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOA48_001531"
     CDS             complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOA48_001531"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCI0789797.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(9567..10265)
                     /locus_tag="NOA48_001532"
     CDS             complement(9567..10265)
                     /locus_tag="NOA48_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0789798.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(10222..11883)
                     /locus_tag="NOA48_001533"
     CDS             complement(10222..11883)
                     /locus_tag="NOA48_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCI0789799.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12101..13501
                     /locus_tag="NOA48_001534"
     CDS             12101..13501
                     /locus_tag="NOA48_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCI0789800.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(13753..14832)
                     /locus_tag="NOA48_001535"
     CDS             complement(13753..14832)
                     /locus_tag="NOA48_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0789801.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(14918..15877)
                     /locus_tag="NOA48_001536"
     CDS             complement(14918..15877)
                     /locus_tag="NOA48_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0789802.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(15889..17400)
                     /locus_tag="NOA48_001537"
     CDS             complement(15889..17400)
                     /locus_tag="NOA48_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0789803.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(17422..17985)
                     /locus_tag="NOA48_001538"
     CDS             complement(17422..17985)
                     /locus_tag="NOA48_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI0789804.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(17991..18854)
                     /locus_tag="NOA48_001539"
     CDS             complement(17991..18854)
                     /locus_tag="NOA48_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0789805.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(18868..19764)
                     /locus_tag="NOA48_001540"
     CDS             complement(18868..19764)
                     /locus_tag="NOA48_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0789806.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(19939..21228)
                     /locus_tag="NOA48_001541"
     CDS             complement(19939..21228)
                     /locus_tag="NOA48_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0789807.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(21200..22717)
                     /locus_tag="NOA48_001542"
     CDS             complement(21200..22717)
                     /locus_tag="NOA48_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0789808.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            22915..23805
                     /locus_tag="NOA48_001543"
     CDS             22915..23805
                     /locus_tag="NOA48_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCI0789809.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOA48_001544"
     CDS             complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOA48_001544"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCI0789810.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(24714..26186)
                     /locus_tag="NOA48_001545"
     CDS             complement(24714..26186)
                     /locus_tag="NOA48_001545"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCI0789811.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(26823..27185)
                     /locus_tag="NOA48_001546"
     CDS             complement(26823..27185)
                     /locus_tag="NOA48_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0789812.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            27408..28160
                     /locus_tag="NOA48_001547"
     CDS             27408..28160
                     /locus_tag="NOA48_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0789813.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(28300..29223)
                     /locus_tag="NOA48_001548"
     CDS             complement(28300..29223)
                     /locus_tag="NOA48_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0789814.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFSFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(29238..29510)
                     /locus_tag="NOA48_001549"
     CDS             complement(29238..29510)
                     /locus_tag="NOA48_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789815.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8803 a         6160 c         5084 g         9635 t
ORIGIN      
        1 ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact gctaatggtt
       61 ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt gcttgaatat
      121 tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc ttttataccc
      181 tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag ccttttcttt
      241 ttcgagtaaa ctgattttgt tagtcatagt tataacaatc atagcaataa aaggagaagg
      301 taagcatatg gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg
      361 cacagttaag gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga
      421 agtgactgtt ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc
      481 aggttgggaa gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca
      541 aaaaattgct cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat
      601 cgcaaacgcc ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt
      661 caatgtagct ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg
      721 taaaaaagca ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc
      781 tcaatatgta aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat
      841 cgaaggaatc gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa
      901 agctgctgct ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga
      961 ggaaaaaatc ttcaaagcag catttgtgcc ttggatattt tcccatctgt ctctttttgt
     1021 tattctttct gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat
     1081 tcaaaaacat gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca
     1141 ccgatgattc cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg
     1201 attgctaact gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct
     1261 actgcaaaaa cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag
     1321 atagccggaa tcatcgctaa aaatgatcct aagtaaggga tcaggtttaa aaaacccgca
     1381 ataatcccca acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg
     1441 attgccacag caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc
     1501 atttcactca gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa
     1561 taaggtgcta attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc
     1621 agagccacta aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc
     1681 ttagatatat cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc
     1741 aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca
     1801 atcgtatcta catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta
     1861 gggatgatca ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg
     1921 atactgtaaa gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag
     1981 taatacaaga ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt
     2041 ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca
     2101 acaagtaagg ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt
     2161 ctgttcttct tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc
     2221 ccaaaccaat agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt
     2281 cttctggaca agcatcaaaa atcaatgata cgtgagctac tgtctttaaa ttcccattgg
     2341 ccatcggacc gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg
     2401 ctttcaaaga aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg
     2461 cagctgttgc tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg
     2521 tcccaatttc tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa
     2581 acagtataac acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac
     2641 gaaaactatt tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag
     2701 gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag
     2761 aagaattagc caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa
     2821 gtaaagctgg caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt
     2881 acgataagga ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg
     2941 tagcggttga tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa
     3001 atgtctacca tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag
     3061 aagcgacagg tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc
     3121 ctgaccaacg attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt
     3181 ccgaaaacgg caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc
     3241 gccatcttgt ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca
     3301 cagtccgcgt gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat
     3361 cgaccttgcc agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg
     3421 atggcaagtt cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt
     3481 ttgaagatgg ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc
     3541 gcgatttcgc actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata
     3601 atctgacatt atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg
     3661 tctatgtacc agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa
     3721 tgaatcagca agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg
     3781 ggaaaatcga agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac
     3841 agaactactt tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct
     3901 gaaaagaaca tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa
     3961 aaccgccgag atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac
     4021 aaggttgttg ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata
     4081 aaggtaatat tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt
     4141 tattttttca acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct
     4201 tggtcttgtt ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg
     4261 atactttgga tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt
     4321 ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac tgactttcat aagcattgcc
     4381 cgatattttt ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc
     4441 agttcacttg tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt
     4501 ccttctccga ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca
     4561 atattcggta acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt
     4621 gtttttatcc tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca
     4681 ttcttattcg tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc
     4741 atattggatc aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc
     4801 tttataccac tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc
     4861 taatgataaa agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt
     4921 cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc
     4981 tttactgtcg aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg
     5041 gatcgtatct gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct
     5101 agaaagattc ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc
     5161 ttgcagataa ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc
     5221 tagattatca tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa
     5281 ctgaggtgtt ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga
     5341 aatatatgga ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg
     5401 gtcaaatcct aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg
     5461 gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc
     5521 catttttggt acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga
     5581 aaaaccagtc aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag
     5641 catattgcca ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga
     5701 tacttctacg ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat
     5761 gttcggcgac tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc
     5821 agtgatttct ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt
     5881 cagattgtac aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta
     5941 aggtatccat agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa
     6001 attactgata taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg
     6061 gaatcgcctt ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt
     6121 tcctgcggca gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc
     6181 gatttcagtg atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt
     6241 catataattt gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg
     6301 gacagatcct gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa
     6361 gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc
     6421 attttgacac cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat
     6481 tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt
     6541 caaatgcttg ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt
     6601 acgaaattcg aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct
     6661 ttatggcctt tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag
     6721 ctgttgtttc acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta
     6781 gacatgctca ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag
     6841 cagagaaaat atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa
     6901 cggcgcttgg aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa
     6961 caaaagataa tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg
     7021 agtcgatccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
     7081 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
     7141 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
     7201 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
     7261 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
     7321 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
     7381 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
     7441 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
     7501 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
     7561 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
     7621 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
     7681 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
     7741 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
     7801 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
     7861 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
     7921 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
     7981 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
     8041 agactaaatt tcaaaaaagt tgaaaagcaa atatcgtcaa tctcttctta tttcttaaaa
     8101 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
     8161 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
     8221 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
     8281 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
     8341 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
     8401 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
     8461 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
     8521 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
     8581 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
     8641 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
     8701 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
     8761 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
     8821 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
     8881 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
     8941 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
     9001 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
     9061 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
     9121 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
     9181 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
     9241 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
     9301 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
     9361 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
     9421 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
     9481 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
     9541 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
     9601 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
     9661 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
     9721 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
     9781 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
     9841 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
     9901 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
     9961 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    10021 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    10081 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    10141 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    10201 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    10261 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    10321 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    10381 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    10441 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    10501 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    10561 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    10621 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    10681 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    10741 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    10801 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    10861 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    10921 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    10981 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    11041 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    11101 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    11161 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    11221 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    11281 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    11341 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    11401 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    11461 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    11521 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    11581 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    11641 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    11701 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    11761 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    11821 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    11881 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    11941 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    12001 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    12061 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    12121 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    12181 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    12241 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    12301 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    12361 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    12421 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    12481 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    12541 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    12601 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    12661 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    12721 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    12781 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    12841 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    12901 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    12961 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    13021 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    13081 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    13141 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    13201 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    13261 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    13321 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    13381 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    13441 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    13501 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    13561 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    13621 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    13681 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    13741 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    13801 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    13861 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    13921 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    13981 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    14041 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    14101 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    14161 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    14221 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    14281 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    14341 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    14401 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    14461 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    14521 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    14581 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    14641 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    14701 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    14761 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    14821 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    14881 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    14941 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    15001 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    15061 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    15121 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    15181 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    15241 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    15301 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    15361 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    15421 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    15481 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    15541 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    15601 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    15661 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    15721 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    15781 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    15841 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    15901 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    15961 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    16021 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    16081 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    16141 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    16201 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    16261 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    16321 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    16381 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    16441 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    16501 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    16561 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    16621 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    16681 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    16741 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    16801 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    16861 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    16921 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    16981 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    17041 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    17101 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    17161 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    17221 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    17281 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    17341 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    17401 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    17461 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    17521 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    17581 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    17641 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    17701 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    17761 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    17821 tcctgatccc tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac
    17881 gatagtaata acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga
    17941 aaccacaatc aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc
    18001 attccagaca tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt
    18061 aatggcagca ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc
    18121 cctgtaaata aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc
    18181 aatggataaa gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga
    18241 gtaggtttgc tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca
    18301 atgcgtgctg cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag
    18361 ataccaaatg cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca
    18421 agcaaattga cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc
    18481 agcaaaacga aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac
    18541 cccgcaagag aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta
    18601 tttttgatgt aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta
    18661 tagctatctg caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa
    18721 gaaataatca gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc
    18781 gttcgaatga tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag
    18841 ctttctggtg ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta
    18901 cacattagtg gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga
    18961 tgcatagccc aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt
    19021 ttctgtctta aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat
    19081 cgaaccaatc agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt
    19141 aatgttaaaa aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga
    19201 gggagagatt ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca
    19261 aacagtcatg atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat
    19321 cggcaagccg acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat
    19381 agaaaaaata atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg
    19441 acaaaaacga ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat
    19501 aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc
    19561 tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa
    19621 gaaaatattc aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa
    19681 taataataaa actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt
    19741 ccaatatttg gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac
    19801 aatcttggtt taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata
    19861 acacctatct gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat
    19921 cctgtataaa gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt
    19981 catgagtgtc tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc
    20041 gttattgatc gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg
    20101 tttcgataat tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc
    20161 caagtaggca ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca
    20221 atatttcaaa aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc
    20281 atatcctacg ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt
    20341 agtcacatta taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat
    20401 ttcaatggct agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc
    20461 tggaccagtc ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc
    20521 aggagacgca aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa
    20581 catccagtta tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt
    20641 actactatca gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg
    20701 ttcagtatct aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg
    20761 tacctgcatg gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc
    20821 tttaaaatca gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc
    20881 tccgttttct acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt
    20941 tttagaagaa atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat
    21001 ttcaattttg atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat
    21061 ttcaccatca gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc
    21121 agattctgct gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa
    21181 agagccaatt aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac
    21241 atctgaccac attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt
    21301 ttacatttgt tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg
    21361 tatcaaatcc actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt
    21421 gaacagttag attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt
    21481 catttattac ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt
    21541 ttgctgaacg aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa
    21601 atggataata gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa
    21661 taacatttac caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag
    21721 tgattaatag acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag
    21781 gaggagcaat ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat
    21841 tccattcatc aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat
    21901 cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat
    21961 gagaaagatc atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat
    22021 cgtacgcttg atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg
    22081 aacttccgca taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt
    22141 cctctgctaa ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca
    22201 tttcattccc taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc
    22261 ttaaatcact ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg
    22321 catctactcc acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac
    22381 accagttata aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat
    22441 ccaaccttct aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca
    22501 caaaatttcc accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga
    22561 cgtcttggcg aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat
    22621 atactgctcg tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta
    22681 cacgcttgac actactaatc aacattgtgg cttccataac tgacctcctt taatttatac
    22741 atgaataata cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt
    22801 tttatcgatt ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac
    22861 ttttattaac aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa
    22921 ctacaaataa acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc
    22981 aagatcatcc agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt
    23041 ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc
    23101 aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc
    23161 agttttccag aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt
    23221 cactatacaa attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc
    23281 gggaaagtgg atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc
    23341 tggtttacca gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca
    23401 ttggagatgt tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat
    23461 tggccttcag atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct
    23521 ggagattttg ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat
    23581 caatacggct tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa
    23641 cccttgtcaa acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga
    23701 atcgaagtga aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc
    23761 ggtaattacg atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta
    23821 ttttataaaa caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta
    23881 tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca
    23941 ccatgcttcg attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc
    24001 aatttcatta tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc
    24061 aagatctgca gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa
    24121 ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc
    24181 aaatttcgtg aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc
    24241 tgctctttct ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc
    24301 tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac
    24361 agctggtttg atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt
    24421 tgcatcttct tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt
    24481 ttcatctttt gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa
    24541 agtagaatct tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt
    24601 caaatatgct ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg
    24661 tttgacacct aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct
    24721 tctgtatgaa gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc
    24781 cagcattcag tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct
    24841 tcccatagtg aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat
    24901 tcgtaaactc tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct
    24961 cgaacagttt tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct
    25021 cgagggtctt catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga
    25081 gtgatgcgcc acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac
    25141 ttgatcgtat ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca
    25201 ccaagggctg gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt
    25261 ttagcttttt gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag
    25321 atttttgctt ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag
    25381 gccatatctc cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc
    25441 gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac
    25501 acgcagtctt tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat
    25561 tggactaacg aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt
    25621 acattgcttg ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca
    25681 tccagttctt gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat
    25741 ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct
    25801 gtttctacta attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca
    25861 aaaactagtt ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa
    25921 tactccaaaa aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca
    25981 ttgaacgtca gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat
    26041 ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga
    26101 cctaattccc agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa
    26161 ctgtcgtctg ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc
    26221 tacccattat aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc
    26281 acatgtttta cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct
    26341 tattggtatt taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg
    26401 aagaaattag cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa
    26461 tcgtagccgt taagataccg atgattgaac aaatataacc aaatgtctct acaacataat
    26521 caatggcaaa agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa
    26581 gaaacggata taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata
    26641 taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt
    26701 aagaaagcag ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct
    26761 tgttttttat tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt
    26821 tattaaatag aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt
    26881 ttgaattgta ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct
    26941 tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt
    27001 ttcttcgtat tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt
    27061 gttcgatcta acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc
    27121 actactttag gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc
    27181 ttcatctcat tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca
    27241 tctttcctag cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct
    27301 tttatcactt aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca
    27361 tctcgttacg taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa
    27421 taaagaaaat gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga
    27481 ttggactgct aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag
    27541 aagtcgatcg tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata
    27601 tccaagaggt cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc
    27661 aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac
    27721 ttgatatgta cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac
    27781 aacaaaagtt gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa
    27841 aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag
    27901 aaatgcaaac tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag
    27961 aagatgaaag cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct
    28021 ggcctgaata tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac
    28081 ggttcactgc atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa
    28141 ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac
    28201 ctaataacaa aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc
    28261 cattctttca caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata
    28321 aggtattttc actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca
    28381 agcttccaga tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc
    28441 gcgtccaatc accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac
    28501 catatccgaa tttgtaaaga caccatcaac tccaagctct ttaaaagaga agcctgcttg
    28561 ttttcctttc tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa
    28621 aagttgatga catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc
    28681 caacgtgatg cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat
    28741 tgattgttct cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa
    28801 aactagaggt ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt
    28861 aatgatcaat ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc
    28921 tttatgatag cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat
    28981 gatcccactg atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat
    29041 gcttttcgtt tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc
    29101 tttcatgacc gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat
    29161 tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc
    29221 cactgctgct tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga
    29281 ccgcattcaa aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc
    29341 caatatatat cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc
    29401 ctattcaacc cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca
    29461 taaaaataat tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct
    29521 ccttttgata ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc
    29581 caaagaaaag ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac
    29641 attataatga tactgtaaat atatctttat tattagtgaa tg
//
LOCUS       DAIGQM010000036        29573 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.036, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000036 DAIGQM010000000
VERSION     DAIGQM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.036"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOA48_001550"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOA48_001550"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCI0789816.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOA48_001551"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOA48_001551"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCI0789817.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOA48_001552"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOA48_001552"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCI0789818.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="NOA48_001553"
     CDS             complement(3376..4683)
                     /locus_tag="NOA48_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCI0789819.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="NOA48_001554"
     CDS             complement(4686..5267)
                     /locus_tag="NOA48_001554"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCI0789820.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="NOA48_001555"
     CDS             complement(5839..7131)
                     /locus_tag="NOA48_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0789821.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="NOA48_001556"
     CDS             complement(7128..7751)
                     /locus_tag="NOA48_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789822.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="NOA48_001557"
     CDS             complement(7754..8590)
                     /locus_tag="NOA48_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0789823.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="NOA48_001558"
     CDS             complement(8607..9494)
                     /locus_tag="NOA48_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0789824.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10794)
                     /locus_tag="NOA48_001559"
                     /pseudo
     CDS             complement(9510..10794)
                     /locus_tag="NOA48_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
     gene            complement(11477..12160)
                     /locus_tag="NOA48_001560"
     CDS             complement(11477..12160)
                     /locus_tag="NOA48_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI0789825.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12178..12795)
                     /locus_tag="NOA48_001561"
     CDS             complement(12178..12795)
                     /locus_tag="NOA48_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0789826.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12805..13629)
                     /locus_tag="NOA48_001562"
     CDS             complement(12805..13629)
                     /locus_tag="NOA48_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCI0789827.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13622..14182)
                     /locus_tag="NOA48_001563"
     CDS             complement(13622..14182)
                     /locus_tag="NOA48_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789828.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14356..15312
                     /locus_tag="NOA48_001564"
     CDS             14356..15312
                     /locus_tag="NOA48_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0789829.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15617..16573)
                     /locus_tag="NOA48_001565"
     CDS             complement(15617..16573)
                     /locus_tag="NOA48_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCI0789830.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16677..17279
                     /locus_tag="NOA48_001566"
     CDS             16677..17279
                     /locus_tag="NOA48_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0789831.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17367..18866)
                     /locus_tag="NOA48_001567"
     CDS             complement(17367..18866)
                     /locus_tag="NOA48_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCI0789832.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18882..19406)
                     /locus_tag="NOA48_001568"
     CDS             complement(18882..19406)
                     /locus_tag="NOA48_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCI0789833.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19704..20453
                     /locus_tag="NOA48_001569"
     CDS             19704..20453
                     /locus_tag="NOA48_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0789834.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20444..21229
                     /locus_tag="NOA48_001570"
     CDS             20444..21229
                     /locus_tag="NOA48_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCI0789835.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21198..21914
                     /locus_tag="NOA48_001571"
     CDS             21198..21914
                     /locus_tag="NOA48_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0789836.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22016..23050)
                     /locus_tag="NOA48_001572"
     CDS             complement(22016..23050)
                     /locus_tag="NOA48_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCI0789837.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23054..24112)
                     /locus_tag="NOA48_001573"
     CDS             complement(23054..24112)
                     /locus_tag="NOA48_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCI0789838.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(24333..25481)
                     /gene="nagA"
                     /locus_tag="NOA48_001574"
     CDS             complement(24333..25481)
                     /gene="nagA"
                     /locus_tag="NOA48_001574"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCI0789839.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25557..26393)
                     /locus_tag="NOA48_001575"
     CDS             complement(25557..26393)
                     /locus_tag="NOA48_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0789840.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26577..27794)
                     /locus_tag="NOA48_001576"
     CDS             complement(26577..27794)
                     /locus_tag="NOA48_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0789841.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27943..28122)
                     /locus_tag="NOA48_001577"
     CDS             complement(27943..28122)
                     /locus_tag="NOA48_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789842.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            28177..28260
                     /locus_tag="NOA48_001578"
     tRNA            28177..28260
                     /locus_tag="NOA48_001578"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28211..28213,aa:Leu,seq:gag)
     gene            complement(28500..29498)
                     /locus_tag="NOA48_001579"
     CDS             complement(28500..29498)
                     /locus_tag="NOA48_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789843.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8843 a         6306 c         5064 g         9360 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgcctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacacccatt gccgcttctc tatccctaac
    10021 cgcctgaaaa gacagatccg tcgtacttgc agctccacca cctggttctg gatgggcccc
    10081 tttgtctacc agatttttac gcagctggaa aaaatctgtt agatagtctg gattttcaaa
    10141 tcccaagctg ttagatagat cttcccgatt ataaaaattc aatcctttct caacttgtgg
    10201 tatttgaata atacagccag ctataaaatc ttcgaatctt gaaatagcat agattcctaa
    10261 ttcttcagtg atttgatagc tgatttgttc aaattcatcc catgtccaat ttgaagctgg
    10321 ttcagggata tttaattgtt caaatatatt tttattgtaa gcaatcgcaa acgaattcac
    10381 cccgttagac agtccaacta attgcccgtc gtaagtcgtc gttgctaaat aggattcatc
    10441 tgcattagaa atatcaatta tcccttgctc cacatattca tctaatggtt caatctgatt
    10501 gatgtattga ggaaattgat tgttcagttg gaaaatgtcc cagatatcat ctgatgctgc
    10561 tagtgtacct aattttgtgt aatatccttc ataatcataa aattcataat cgatcgtcac
    10621 atggggattt ttttcttcat aaagctcgat tacttttact gttgcatcgt gtcggacttg
    10681 cgaaccccac caagccatgt tcagcgtgat ttttttgtca tcttcttgcc cacaagccgt
    10741 caagaagaat aacataacac ttaaagctaa gatgattctc attcttttct tcattctctg
    10801 cacctctact tccattgtta tttttcaata tactgtattt ttatacagaa catatttatt
    10861 aaacgatctt tttcaagggg aataaaaacc aagacttgcc ttatcgttct gcctaggatg
    10921 aacaactcaa tactttcaag aaaaattaga tagtgctgat tcttctttca tcgctaaaaa
    10981 cacttcttgc ttcaatgatg ggaggataat tacgcaaaga aaaaaggata tcagacaact
    11041 gcccaatatc cttgacatag ctaaataagc atgcttcttc gtgtgcgctc ttccctaaaa
    11101 aacagaaaaa taactagtaa ttctgtatga aattaggtac aatatacacg tcgatgcaca
    11161 agcattgact atggcaactt gattggtcag ttcccgctga cttttcaagc cccgacaatt
    11221 tagctgctac taaattgtcg ggtgcctttt ttagttttta ttcgtttttc attctataga
    11281 aagcgcttca ataaatcaag acattttttt gttagaatgc taataataac aaaaggtttt
    11341 aactcttctt atgtacatta caggtaaaaa aacaaaaaaa tttctctttt ttttgaattc
    11401 tgaacaaata gtactggagt acaaaagacg aggaagagcc actatctgct cttcctcgtc
    11461 ttttgattct cacctgttat tcatgattct ttttctcagt ttcccgatat ttttccattt
    11521 tacgactaaa aagctctccg ctacttggtg gcgtatatgt gatggcattt gctcctgctt
    11581 gaatggtctc agcaatactt tcttccgttg gaccacctgt cgcaatgata ggaagttcag
    11641 gatatttttt acgaaaatgg cgtactgctt ctgcagtttc tttacctgca ctgatattga
    11701 taatcgaaat accagctgct aacttttcat ctatttctgt atatttcgac gttaccgtac
    11761 tgataactgg aatatcaact actcgacaaa cttcttttac tgtctctaaa ggcgtaggac
    11821 cgttcaaaac gacccctaac gaaccttgcg cttctgcgaa catgctcatg taggaagaac
    11881 gagcaccttg tgtcaaacca ccacctacac cggagaaaac tggaatgtca gctgcctcaa
    11941 taatgctttt agtaatcgct ggatgaggtg taaaaggata cacagcaatt actgcattcg
    12001 catttgtatt acgtatgatc gcaatatccg tagtaaagat gatcgaacgg atcaattttc
    12061 caaatatctt gatcccgctt gcttctaaaa tgatttccgg tactcttacg atatcttttc
    12121 tcaattccgt catgatttct ggcgtaaatt gttctgccat cagccacttc tcctttgcta
    12181 tctccggtca tactgattca attgatacgt ctcgatgacc tggatgattt tttgcgcata
    12241 accggggtct gtcgcataac ctgcatcttg caatgcttgt gcggcttcct gatagttggt
    12301 ggccgtaatc actttttcat acagcgcagg attccaatct actccttgga cgaacagttg
    12361 tgtatggtca tccatggact gttcccatga atcatacact ttgaagtctc cttggatagt
    12421 tatccattct tcgttaacaa attcctttgt ttccaggctt actttcttct gatccccata
    12481 agccttgatc ccgaaaagat tattgtattt gctagccaag gtactttttc cccaatttga
    12541 ttctaatata gcttgtccta aaatgatact aggaagcact ccataaccat cttgtagttc
    12601 ttgggcatgc ggaacaagcc gttcaataaa ttgctgatgg gattgcgctt cattttcttg
    12661 ctgattatca gtaaaaggag aagacagatt cttcaaggaa aaaacaaagg ctaagagtat
    12721 cactgctaca ccggcaacca ctgctggcca acggatattc ttgcgctttt gctttttcca
    12781 cttttttttc gccatgatca attcctactt ttcatttaat tcattcagat attcttctag
    12841 cgtcaattgg tgtttggtga tatactcagc gttttcttta ccgacataac gtaagtgcca
    12901 aggttcatat gtgatcttag ttatatcttc gtgtcctttt ggataacgaa cgataaatcc
    12961 atactgcgca gcattatctg cgatccattt agctccaggc tgatctccgt aacttgcatc
    13021 caatacagta gaaggataac tgttgtacca gttttgatcg acgacatcga ctgccagacc
    13081 tgtgtggtgt tcgctgtatc ctggctccgt aatcgtttct ttagtaatct ttgtcgcctc
    13141 ctcttctgat acaccttgac gactcatcac atcttggaca ttttgttcga aaacttgttg
    13201 ttgggatgat acagaccggt aagctgagac catcactaat ggaaatccag ctgcttcagc
    13261 agccttggca aatgcttcat attctggagc aatgcgtttg tcgatcaagt atccgttact
    13321 taatgatgcc aattgagtag actcatcaat ttctttttct aatttgtgat ctggaccaac
    13381 caaaactagc ttccaatcgt ctgttttaac atctggcaat tgtttggacg tacgatcttt
    13441 tgtttctttg tcctttacct tgctgctggt tgtttgactg ttcttttctt tactagcagt
    13501 tgttttggtg cttgttcgtt cgactgcttg attgccggct tgaacatgcg aatcatcatc
    13561 gctaaaaata acatagccca ttgctgcgat cataatcaca actgctccaa atcctaaaaa
    13621 tttattcact tgaaaaatcc tttcgttgtt cttcacgttc cccattcgcc tcatgaacgt
    13681 aagtttcttc cagattttca ttcacccaat cgagaagttc gattttttct ccttcgatct
    13741 gtttttgaac atctgctggc agacgaaaat tcaaaatatc atcatagccc cattcatcat
    13801 attgaatact tactttcaag tcaaggtatc taccagcctg ctgattattt ttcaaaggga
    13861 tcagctcgac ttttgctgct ttgctgctaa gccatttttg cgcgatgcgt gttttgattt
    13921 gcttgtactc tgcaacggca acgtttcgtt tttcgggaaa aataatcgtt tgacgcaaaa
    13981 tcttttgcgt tagcatccat tcataatcag tgaaaagatt ttttactttc tgcatcgctt
    14041 cagatggcag atttttctcg ccatctttcc atttttgcca ttgttctgga ctgatcagca
    14101 agtattcatc taaaaaattt ttttcagttt caaactgttc taataataca ctcataataa
    14161 gatcaatata tacttgatgc acgtttatcc cctcctttta actattctac ttaagttttg
    14221 atcaaaaagc acctcttaaa tcgctgcttt catttttttt aatgtttcaa gtcctctcct
    14281 ctttattctt cgtgattttt gttataataa tagacagaca agaaactcaa tccaactatg
    14341 aaggagcgtt ttcagatgaa aaaatatcaa tggggaatcg ttggtcttgg taccatcgca
    14401 catgagtttg ccgaaagctt caatcaagag acgagcgaac taacagcagt tgcttccaga
    14461 acttcagaaa aagcggaaaa cttcgctcac cgttacaata ttccaaaagc ttacggaagc
    14521 tatcaagaaa tgttagacga tgctgaaatc gacatcgtgt acattgctgt accaaataga
    14581 cagcatatcg accatatctt ggcagcattg gaagcaggca aacacgttct atgtgaaaaa
    14641 gccatcacga tgaataaaaa agaactggct gacgctatgc gcttagcaga agaaaagaat
    14701 ttgatcttag cagaagcgat gacaatcttc aacatgccac tttatcagca gttacgctca
    14761 ataatggata caggaaaact gggggcttta aaaatgatcc aagcaccttt cggcagttac
    14821 aaagaaccag accctaaaaa ccggttcttc aatccagaat tagctggagg agctctgttg
    14881 gatatcggta cgtatgctgt atctttcgct cgtttctttt tgagctctca acctgaagta
    14941 gttgcctcta caatggttcc ttttgaaaca ggcgtggacg aacaatccgt cactatcttg
    15001 cgtaacaaag aaaatgaact tgctgctgtc agcttgactt ttcaggcaaa aatgccaaaa
    15061 gtcggtatcg ttgcctttga gaacggttat gtgacgattg ctgattaccc gcgtgctgat
    15121 cgtgcggaga tcttatttac agatggtaca aaggaattca tcgaaagcgg gaatacatct
    15181 gaagcaatga attacgaaat aaagaatatg gtacacatga ttgaaggtga cttgcccaat
    15241 cgctctctct tcttgacaaa agatgtcatc gaaatcttgg atcaaatgca agttctatgg
    15301 aaaaatatgt aattttaaaa ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    15361 ccaaacaaaa atagctcctc ctatttttcg tttggctgga cttattaccg cagaggaaag
    15421 cttttgaaca ccgtttaaga aagaggttgt gagcctaccg ttcagctccg agtcacaagg
    15481 agcaatttca aaaaacagct tctcatgttt gttgaatatt gtgacttgtg accgaggagt
    15541 tgacaggaga acaccgttta aagaagaggt tgtgaaatca gctttttgac ctgaatatta
    15601 gctgaattca caacctctat ttttggattt tttgttggga gaattctgcc ttgatttcaa
    15661 taaaactttt aaaagactgc aaaaactgga acaattctgc tcgatcctcg aattcagggc
    15721 gactagtcgg cagaggcatt tgccgataca atacataaac ttcttcaata cgtgttaaaa
    15781 tttgtctgcc atcatttgac tctgaaaatg tttctgcagt ataaatcaat aaaccataga
    15841 tatgttttcc ataataagct ggttgctgga ttctctctag attttccagc atgtctttaa
    15901 tcacattggc ctgtgctctt ctcatagaga agtaagtttc gtagtatagc ggctgtctga
    15961 gccagtagtt ttcttgatgt tctctggcat cttcttggct ttcgcgaatg aatgtcagta
    16021 aatgttcgca tttgatctgc acatcttctt tattttctga taaaagaaat tctgccattt
    16081 gtctcaaaat atttcgaaat tctttttcga tctgtatttg gttttccttc agctgcttcg
    16141 tacgatctgg catgtaaaca tttgcaagca aagcaaatac taatccaatc gccattaatc
    16201 ccgcttcatt gccgatcagc tgccaagaca tgttttcctc cactaaataa tgagtgacca
    16261 aaaccgaatt tactactatc ccttcggtta atttgaagcg agaggcaagc gggatgaaca
    16321 ggaataaaaa aagactgaag ccaaaaatag tatacccaac agcaaaaaaa ctgaacagtg
    16381 ctgttgccgt agctaatata aaggctgcga ttcgattcat gcccgtacgc aatgtagagc
    16441 gcttggtatt tcctacactt aataatgcaa tgatccctgc agctggccaa tacaacagcg
    16501 ataagctacc cgctgtgacc atcgaaaaga agacactgat cactgttttg actgttcgca
    16561 ttcctatacg catttacttc cccctttttt attttaatta tacttgaata atgaaaaact
    16621 agctatcaga caaaagttta ggtatgatag taaaaagacc aaaaaggaga atctctatgc
    16681 aatttggccg ttttcgacta ggtatgcgta cgatcaaaag tgccttagct gtttttttat
    16741 gtatcttgtt ttttcatttg actcaacgag gaatcccgat gattgctgca ttatctgctg
    16801 ttttttcttt gcgtcaggac ttgactacaa ccgtttcttt tggaaagtct aggatcatcg
    16861 gcaatacatt aggtggtaca ttagctatca tttatttttt tgtcaaaagc tattttcaca
    16921 atgatttttt ggtagaattg atcttgcttc ctattctagt tattattgtg atcgtcgtgt
    16981 cagatggtat taacaataat tccggtatca tttccgcaat agctacgttg ttgctgattg
    17041 cgttgagcat ccctcaaggc gaatccgctt tgtatgctat ccaacgtgta ctagatactt
    17101 ttatagggac attcattgca atcggtatca atttctttct tcgtcctcct gaaacagaaa
    17161 agaaggaaga actatcagaa gatttggtcg aactccaaaa gaaagaacga ttgctaagaa
    17221 caaatttaca agagatagaa gctaagatcc aaaaacaaaa gaaaaatagc gaggactaat
    17281 tttcttttgc aataaaataa aaaaatggag agaagaactt taaaaagtct tcctccattt
    17341 ttgattgaac ggtgaagtgt actactttat tcttccttca tcgagttttg ttctgcctct
    17401 tttggcgctt catacatatt tacttggcta gtagtcccac gtgtcgacaa attctctacg
    17461 atttccttca agtcaagtcc tgttgtcgct tttagtgttt cttgagtaga agaaagcaaa
    17521 tttgtggcat aatttgtcac tcggttcgct ccactggttt ctcctgaact gcttcctgta
    17581 tcgacaacag agattttttc gatatttcct agcggctgtg ctgcttcgcg catcaattgc
    17641 ggtagcatat cgataaccat actcaagaca gctgcttcgc catattcctt gaaggcattg
    17701 gcgatctttt gttttgcttc ggcttctgct tttccttttg ctagtgctgc ttcggcttct
    17761 gcttgtccag ctaaacgtgt cttattggct tccgcttctg ccagtgcttc cacacggaat
    17821 cgttctgctt cggcttcagt cacttctttg actttttgag cttgtgcttc ttgttcttta
    17881 gcgtaccgat cggcatctgc ttttttcttc acttccgaat catattgctt ttcacgacgt
    17941 gtgatttctt tttcttccag ttcgatttgt ttttggcgtt ctacgatttt aatctgcatt
    18001 tcctgttcga ttacttgttg ttgtgctcgg gcactttcta aattgtaggc ttggtctgct
    18061 tttgctttag caacatcttg ttcttgtttg taggttgcta atttcagttc tttttctttt
    18121 aatgattctg cgatctctgt ttgtcgctgt aattcagctg cttgtgattc tttttctgct
    18181 tgagcttttt tgatacgcgt ttcttttaga gcttccgctt ctgctatatc tgcatctctt
    18241 ttgacttggg cgattcttgg tttccctaaa gagtcaagat aaccgttttt gtctctgacc
    18301 tctttgatag tgaaagaaac gatgatcaac cccatttttg caaggtctac agaagcgact
    18361 tcttgtacgc tttgactgaa cttatcgcga ttttgataga tttcttctac agtcatagaa
    18421 ccaagaatcg agcgcaagtg tccttctaat acttctcttg cttcattttc cagttcttct
    18481 cttgtcttgc ctaaaaactg ttctgctgct gtagcaatct cttctacaga tgaaccgatt
    18541 ttgatgatcg aagtaccatc acacatcacc ggtacgcctt gttccgtata cacttcaggg
    18601 gtggagacgt ccaatttact cgataataga ctgatccgat tcgaacgttg aaaaactggc
    18661 aagacgaatg cgccacctcc acgcacaatt ttgattttgt tattgctttc atcaatgtgc
    18721 acatttttgc ttcctaaata acttccactg atgatcaacg cttcatccgg ttttgctgtc
    18781 tggtacttcg ctacaaagac gatcagcaac atcagtaaaa tcaaagctgc gattgcgatc
    18841 gcgataaaaa caactggtat ttccatttaa cacacgctcc tttaagcttt tatcatgctt
    18901 tcataaggca tgacataaca gattctttcc ttgatctcaa tgatcaatac tttcgttccc
    18961 cgctcagctg tctgttcttg ggggctgtaa aaacaagctg gacgactaat ggaaccggta
    19021 acacttttca actgaatttc tcccatacct cgtacaggga tcggtgtgat cacaacagct
    19081 acttgtcctt ccagagtttt ttcagaagac gacatcgttg attcggcatg tttcatcggc
    19141 atcaatatat agaaattaag caaaaatacc aacactatcg atatgcctcc actagcaata
    19201 aataaaaata aagatgattg atctgttaaa cgctcaccta gaaaaccaaa taagcttgtg
    19261 aaagttaacc aagggataat aagcatcgga tcaagcgggc catcaaaatc gaatacatct
    19321 ccaaaaataa tcaataggac tgccaatcct gcacaaatca gcaatgtata ccaataaatc
    19381 gtctcaagtg cgattccccc tatcatatac acgcctcctt ccatttctac gtctatcata
    19441 ccaatgtttg aaaattctgt atagcttctt ttaccgactc agtggtgttt tttataggaa
    19501 ggttgtgttt atcgttgaca atttgttaaa tttttgtttt catgttaaaa ttttcacaat
    19561 aaattccttc gaggtagcct atgtttcctt tttttaagaa aaaaccatta aagctccaga
    19621 acacgatcat ccttgtcgtt tgtttctcca cattcgtttc tttgattgtt tctgccatat
    19681 tgatcaggaa ttttattctt tcgatgaacc gatctagtgt gtcagataaa atctctagca
    19741 ttgctaaaat cgttgccaat gataaactca tccaaaaaaa gctgcagact ggtgacccga
    19801 cacatgcgat tcaaggaata acaaatgaaa tcatgattgc atcgaattta gattttatcg
    19861 ttgtcatgga ccctgaaggc attcgatatt ctcacgcaga cccaagttac atcggtcttc
    19921 ctttctcaag tcatgaagat gtgaaaaaag tgattggagg acaagaattt ttctctgaaa
    19981 aagaaggaat gttagggttc ggcttccgct atttcgtccc tatttattat gatcaagaga
    20041 ttattggtgc agtttgtgtt ggcttaacaa acaacacgat tgacaatcaa gtcaaagatg
    20101 gacaaaaaat gattgttttt tcattgatta ttggacttag cgtaggcatc ataggcgccg
    20161 tttttcttgc ccaaaaaatg aaaaaagtac tgcttggact tgaaccacaa gaaatagcag
    20221 aacagttaag tgaaaaaacg attatcgaaa atgaagtaga tgaaggaatc ttagccatct
    20281 cttctgataa aactatcctc ttgatcaata cacctgcaaa aaacattttc taccaaacag
    20341 agcagctatt ggatttcgaa gtaggaaaaa aatcagtgat aatctatatg acgttttgtt
    20401 taaagagacg attgagcatc aaacgaccgt tcggactcaa tccatgtatt taaatgggat
    20461 agaaactatt tctagcgtta cacctctttt tagcaatgac cgttttttag gagcagtcgc
    20521 aactttacga aatcgatcag aagtaatgaa attaatggag gagcttgggg ggacgaaaca
    20581 atatataaac tccatgagag ctcaaaccca tgaattcatg aataaacttc atgtcatttc
    20641 tggtttgatt gatttgaaga agtatgaaga agtcacccat tttatccagc agctaaatca
    20701 aaattataaa aaagagattg gccaagtctc aagtctgatc aaagtacctg caattgccgg
    20761 ttttttatta ggcaaaataa acgaagccaa agaacaatct gttgaaatgc tgttagaaag
    20821 cgattctttt atccctaaaa tggagatgga tgactccatc cattcacttt tgcaagtgtt
    20881 agggaactta cttgataatg caaaagaagc cgtgctacaa aaacatgaaa gaaacggaca
    20941 ggtccggatt catttaaact atgacacaga agctgaagta ttcatcgtga ccgtctgcga
    21001 tgacggtgtc gggatatcag aagaaatctc agaaaaaata tttacgctag gtttttcgac
    21061 gaagggaatc aatcgtgggt ttggattgaa tctcatccat tcaatcgtca aacgccacgg
    21121 tggattttta gaattttcca aacaaacaaa tggcggtaca atcgtctatc tagaattacc
    21181 aaaaaaggaa gatcaaaatg atgacaaatg tcctgataat cgaagatgat ccaatggttg
    21241 cagaattgaa tcgtactttt gtggaaagca tccctaatat gaacgtaatc gaaagtttca
    21301 gaaatgtaga agaaggaaaa aaatatttca gacaaaaaaa cgcagatctg ctgctgcttg
    21361 atgtatacat gcctggcgaa agtggtatcc attttttatc ttggcttaga cagcaaggaa
    21421 atgatatccc agtgattttg atcactgctg cagatgatat cgaaaccata aagaatgtga
    21481 tccgctacgg tgccttagat tatttgatca aaccgttcac tttgcaacgt tttcagctgg
    21541 cgatcgaaaa gtatcttgct ttctctcaga caatccaaac gactgaaaaa gccgatcaga
    21601 aattgatcga tcaagtattc aaccacacca ctcccattca cgaaatacca tcattcatcg
    21661 atttgcctaa aggtctgtca aaactgactt taaaaaaaat aagtgcattt attctaaaag
    21721 aagatactat tttttcaaca aaagaactgg ctcaaaaaag ctcactgtca cgtatatccg
    21781 tcaagaaata tttgaatttt ttagtagaac aagatatatt gaacgaaaga atcaaatatt
    21841 tggaaatcgg ccggccgcta acctgttatg aattgacaaa gaatgggcgg aaaaagctca
    21901 cagattactg ttgagtcatc gaattatccc atacaaaata gtccaagtat acagaagtaa
    21961 caactgttta cttggactat ttttaaacat tttattgacg aatatccatg ttttcttatc
    22021 ttaattgacg ggctttagga agagatacct catttttcgt ttttccagtt tctattattt
    22081 cacgaaagtt ctcgaaactt gtcgaaatca tatttgataa tgcctcatct gtatttgaac
    22141 ctacatgcgg ggttacaaga actctagggt acatttctac taattgctgg atagcagggt
    22201 ctggaatcgt ctcccatggc ttgaaggatc ggaaaaaaac ctctgtttca tttgcaaaaa
    22261 catcggttgc aaaaccagct aaatgattgc ttttcaaagc tcttaaaata gcttcattat
    22321 cttgaagctc tccacgggct gtattaatca agatgctacc ttttttcatt tgagctaaaa
    22381 atccttcatt gatcatttga tcgttttcac ctgggatatg aggtacatga atactgacaa
    22441 tatcgctttt ggctaataac tcttcaagcg agtggaacgt caatactttt ttagcagctt
    22501 ctgtctgatg aatatcgtag ccgatcactt tggctcctag tcccttaaac aaaacagctt
    22561 ccgtcaaccc tatcctgcct gttcctatga tccctactgt gcaatttctg atttcacgac
    22621 taaacatttg ctcatccact cgaaaatctt tgaaagatgt tcggatcgtc gtatacgcag
    22681 tatttctcaa aagcatcatg gcaaaagtca aagataactc tgctatcgca tttggcgaat
    22741 acgatggtac acgggctact gtcataccaa aatcagctgc cgcttgtaga tcgatatgat
    22801 tgactcccac agtccgtgta aaaacataac gaatcccata ttcctgcatt tttgcaagat
    22861 tggtctcatc tgctatacaa tttcccctca acaatacagc atcatggtcc tttgctgaca
    22921 cgatattgtc atgtgtcaac agttcttcat aaagactgag atcataatgg taaatattca
    22981 atttttcaaa aaaatctatc tcgttcggac gaacaccgta acatgcgatt ctcatacttt
    23041 cttcctccat ttcttatgaa aataaaccta tgccatgaat catttgtaat acaacgatcc
    23101 atacaggtgt cagtaccaca gcaaaaatag ttgacagtaa ggatgcattg gaggctaaaa
    23161 gtgcctccct atcaaaactg atagcatagg ctgctgccac tgttgcagct ggtgtagcca
    23221 tcatgataac gattgttgcc agtgcttcaa aattgactgg tagaatattc gttgccgtca
    23281 aaactgctag aatcacgata ttcaatgcag gtacaaatac cactttgact agactgtaat
    23341 accatgaagt tttttcagat gcagcttttt tgaagcttac ttcacctaat gttgcgccga
    23401 ttgctagcca cgccaatggt gaacttaaac cagctaaata atccatcggc tgaaatagcc
    23461 acggtgcagt ctggtcaatt cgcaaaaacg ctacttggct tatctctcct tctgcacctg
    23521 taactgacac ttgtggcaga tacccttgga acagccaaat gaaaaggccg gcaaaagtag
    23581 cgataatgat tggattgacg aacatcgctt tgatattttt agcttccatc ttcaagccac
    23641 tcatttttat gtatccataa gaatacaaaa agattcggta gccaatattg aaaattgagg
    23701 aatacatcac gccgacagga ccataaatcg cactgacgat aggcgttccg aaaaaggtcg
    23761 tagaaccaaa gatcgtcagg acacgcaacg ttgtttgctt atccccttta tagcttaaga
    23821 aaaaaggttt tgaaactaga ataagaataa tataaataac taatccccaa atcaagacat
    23881 tgattccttg catcagtaat tctgtattga tatcttgcat gaaagctcga aatgccagtg
    23941 ctggcaaagc cactgttaag acgactttcg atagaatttt tccaacagat tcagaaaaaa
    24001 tccccttttt tctacaaaca aaccctaata atataataaa aactgttgaa gtgattgcac
    24061 tgacaatcga catatctgtc aaagtcgatc gaaaaatgtc aaataagttc atctttctcc
    24121 tcctaattat gttcatttat tcacaataaa aaaagctttt attttgctaa tacgtattaa
    24181 catttttaat tttatcttta cattgttact tattgaacaa taggaaatta aagaaacttt
    24241 tgaaacttat gtaaagtgat ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa
    24301 gaagtttagt tttaaggtta acttaaatta tattatgcgt ggaaacgttc cacgccatct
    24361 agataagttg cttccaatgt catatcaggg ttcaatacga taaagtctgc atcgcgtcct
    24421 tgagcgattt ttccacatgt atcatcgatt ttacagctga ttgctggaat cagactagcc
    24481 atcatgactg cttgttctgg tgttgctaat ccccagtcta caacattttt aattgcttct
    24541 ttcaatttca atatacttcc agctaagttg ccagattcta gacgtgctgt tccttctttt
    24601 actactactg gaaattcgcc taaattgtaa tttccatcag gcatcccacc ggccatcata
    24661 cagtctgtaa ttaatgcgac atgatcatgt cctgcttttt ccattaggat tcccgcagca
    24721 tttggatgta catgatggcc atcacaaatc aattcagaaa agacatgttc taaagataat
    24781 aacgcaccca ccatacctgg ttcgcgatga ttcaatccac gcataccatt gaaagcatgg
    24841 acaaatacac ttgcgcctgc ttcaacagct ttttgcgctt cttctagtgt agcattactg
    24901 tgtcctagag aaacaactac tccttcttca gtcacttgtt tgacaaactc ttctacacct
    24961 tgacgttccg gtgctaaagc aatttttttg attaaaccac ctgaagcttc ttgccattca
    25021 tggaaagtat ccaaatcagg atccccgaaa taacttgggt tttgtgcccc tttgtgttct
    25081 tctgtgaaga aaggaccttc aaaatagatt cctttgattt tagctcctgg tgcttcctga
    25141 tacattttgc cgattgtctc agctacatct tttaaacgtt ctttgcttga cgtcaatgtt
    25201 gttggtaaaa atgaagtcac tccacaagat aacagacctt cagacatcac tttgatgcct
    25261 tctgcatcat tatccattac atcatgattc atatagccgt gaatatgtgt atctaccaaa
    25321 ccaggagcaa tccatttgcc gctttggtca atgatgttga cttctccctc aggtagttct
    25381 ttggtgtatt caccaaaaag tccatcggta atttcaagat agcctgcatg tttgacacct
    25441 gacgctaaaa agaatttgtc agcatagata aaagttctca ttctattctc tccctttgtt
    25501 tttctacctc taaagtactc ttatttagag aagaagtcaa gaatggtcta caccatttac
    25561 aaattttttg aaatttgttt cacagcttgt gctaagcctt catagaatgc tgctctttct
    25621 ggttcttctt tacgcttgta tattaagctt ttaagcacaa ataaatcatt gaggtaatag
    25681 tagctattct tctcttgagc ccaatagatt ccttgattca cctgttctaa cgcttcgtcg
    25741 atttcatttt gatggaataa gaaatttcca taattataaa aaatttgcga aaattcactt
    25801 tttgatcgtt catcagctga ttgatgcagc agttggatgc ttcgactcaa atagtagcgt
    25861 gcttcagccg tttttcctgc cacaccatat atttttccga tacaactaat cagttgtatt
    25921 tctgtgtcag aaacatggat tctttctttt tggctagagt agcttaatgc ttctttcaaa
    25981 taataaaggg actgagagat attttgacgc aacgtgaatt cgcaaacacc gagataataa
    26041 taatagcgtt gaaagtcagt tgcttgatac agattttcag aaatatcaga agattttagt
    26101 acttgttcta acttccgata atcacgtttt tggaaacaac tatccaacag ttcaaataat
    26161 ttatcgtttg tccgagtagt ttttcgagag agattcatca catgatcaat cgttacccct
    26221 agccgttgac aaatctgcat catcaccaat acattcggca gttcctcatt attttcgatc
    26281 cgacttaata cactttgtga acaaatatca tgcgaaagca ttttttgcgt cattttttgt
    26341 tcttttcgaa tctctttaat gatcgttcca aaggactcga ttaacgtttc cataagtatc
    26401 ctccccaaaa tatgcgtatt cgcattctat tcgtatttta ctttaggaag tcgcaaactt
    26461 caagaaaaga cttgcaacta aataatatac tttagttatt taagaaaact ccactagaaa
    26521 gagagcctca gtgtgtttgt ctgtggccct cctactgaaa aatttggttt ttaaaatcat
    26581 ttttggcgat aggttgctag gaattctctc attttcttag ctgtttgttt caaatcatcc
    26641 attttaggaa gataaacgat tcgaaaatga tctggctggt tccaattaaa tccaccacca
    26701 tgtacaagta gaatatgatg ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa
    26761 atattgaatc gctttgtatc aatttttggg aatatataaa aagcagcttt tggttttacg
    26821 gctgaaagac caggaatatc attgattgca ttatagatat attctctttg ttcatagatc
    26881 cttccgcctg gcaggagcag ctcatcgaca ctttgataac cgcctagcgc ggtttggata
    26941 atttgctgag acaatacatt ggaacacaaa cgcatggagg acaacatatt cagcccttct
    27001 atatagcctt tgacgtgtga cttatctcca cttaggacca tccagcctac tcgaaatcct
    27061 gctacacgat gagatttgga tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat
    27121 gtagcaatcg gaatatgttc tagaccatcc atcactaagc gatcatagat ttcgtcggaa
    27181 taaataatca ggttattttg tcgagctact tcaacgattt cttctaataa ttcttttgga
    27241 taaagtgccc cagtaggatt attaggatta atgataacaa tagcttttgt ccgactcgtt
    27301 atttttgatt tgatatcatc aatatcagga taccattctg cctcttcatc gcaaatataa
    27361 tgaacaggtg tgcctccagc taatgcaata gaagccgtcc acaacggata gtccggcatt
    27421 ggaaccagta cttcatctcc attgtccagc aacccctgca tacacatcgt gatcaattcg
    27481 ctcactccgt tgccggtgta gatatcattg atcgtcacat tcggaaaatg tttcagttgg
    27541 caatattgct caattgcttt tctagcagaa aagatcccct tggaatctga gtagccttct
    27601 gagtcacggg cattcatgat caaatcacga atgacttcgt ttggtgcttc aaatccaaaa
    27661 ggtgcgggat ttcccgtgtt caattttaaa atactaatgc cctcttcttg catccgctcc
    27721 gcttcttcta gaacgggacc gcgaacatcg taactgacac cttctaattt gttggatttt
    27781 tcaaattctc tcatcactta gccaatccct catttcaaaa agttagaact ttccaaattt
    27841 tttgttattt actatttcaa tatcatactc catcctagaa aattttgcca cttatttagg
    27901 aaaaacgtaa gtattaaaaa aacacaaaca agcgttgaga acttaattgt catgatagtc
    27961 attccataga ttcgctgccc aatccattgc aattccacaa atgattccta gcataaaacc
    28021 aagcaaaaaa cgtccgaatg caagtccaat caatacacct aagatcattc ccagtcctga
    28081 aaattctccg tcatatttct ccatcttaat aagtcctccc atttttgagc ttgacaacta
    28141 tgtaaaacct cgctatcatt agtgtgttat tattacgcag atgtgttgga attggcagac
    28201 aagcatgatt gagggtcatg tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca
    28261 ctacaactcg tgaagttaat tttgcttcac gagttttttt gtttgaacgt ttctttatgc
    28321 cattatatac atatcactgt atcctttaca aaaagaacgt acaatcatgt aaacagcctg
    28381 aggtgagtat atgaaggtcg gaaacaagct actcgtagaa acttgcaagt gttaaaacaa
    28441 ttaatcgaaa aacgagtaaa atccctcacc taatactaaa gcgagggatt ttttgtatat
    28501 tatctgttta tcaccgttat tataaaggta caaataccaa gcacggttaa tccaaattgc
    28561 ataaattcat ttttttgtac actcatgctt ttcattagct ctttaactgc cattagtact
    28621 aagatggcga taacaacata aagtatatag tacgtccgca ttccggaagc ccatactgtg
    28681 ggagaaaatc ccataattaa ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa
    28741 atagaagttt tcttattgtc aaaacttaaa taaattccaa caattaaaca tagtaataat
    28801 gccaagacta ctaaagtagc tatccaagta cctggataaa aaagtgacag tttcgttcct
    28861 aactctgtaa agagattatt caggttacta ctactccaaa tcattgccct tttatttcca
    28921 ttgacgtaag taaagctttg acccattgta ttaccaaaat aaataatcag gtttaagaaa
    28981 aacggtaatg cagtcaatat acgcacataa tagttttgac atttcctata tgttagaagg
    29041 aaaattaaga aaaatagcaa taaaaataag atattcatgt ctaaaaaaaa cggctttcca
    29101 aatgatgaaa tacctaaatc taacttatta agaaagttga aatttttata ttcaggaaac
    29161 catttattaa tttcatgtgc agcacgtaat gcattccctg gagttgtcaa agagaaaatt
    29221 aattctgcta agcttattat tgaaaatact gataacttat aattatatcg tccattgaca
    29281 atcaaatata aactaactat acttgttaga acaaaaaaac aggcgttgac ttgttcttga
    29341 ttagttaaaa atatcaataa aggaatactt acccaatata tttttctatt tatttcttct
    29401 cctcttaaga gttgaaaaaa cggataaaaa gttagtaaac taaatgctac tggccactga
    29461 tagttcaagg tggttgctct ccaaccggtt tcccccatta ctgtcaatgg tattaaacag
    29521 tatatagagc aaaccaataa taaattttta acatttattt tctcaaaaac ata
//
LOCUS       DAIGQM010000037        29107 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.037, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000037 DAIGQM010000000
VERSION     DAIGQM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.037"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..1030)
                     /locus_tag="NOA48_001580"
     CDS             complement(<1..1030)
                     /locus_tag="NOA48_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0789844.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="NOA48_001581"
     CDS             complement(1112..1801)
                     /locus_tag="NOA48_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0789845.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOA48_001582"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOA48_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCI0789846.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="NOA48_001583"
     CDS             complement(2328..2831)
                     /locus_tag="NOA48_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCI0789847.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOA48_001584"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOA48_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCI0789848.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOA48_001585"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOA48_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCI0789849.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOA48_001586"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOA48_001586"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCI0789850.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOA48_001587"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOA48_001587"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCI0789851.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="NOA48_001588"
     CDS             complement(6443..7462)
                     /locus_tag="NOA48_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0789852.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="NOA48_001589"
     CDS             complement(7635..8540)
                     /locus_tag="NOA48_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0789853.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOA48_001590"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOA48_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCI0789854.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOA48_001591"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOA48_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCI0789855.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOA48_001592"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOA48_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0789856.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="NOA48_001593"
     CDS             9753..10397
                     /locus_tag="NOA48_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0789857.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="NOA48_001594"
     CDS             complement(10453..10956)
                     /locus_tag="NOA48_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0789858.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="NOA48_001595"
     CDS             11553..12518
                     /locus_tag="NOA48_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0789859.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="NOA48_001596"
     CDS             complement(12617..13789)
                     /locus_tag="NOA48_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789860.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="NOA48_001597"
     CDS             complement(13776..14921)
                     /locus_tag="NOA48_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789861.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="NOA48_001598"
     CDS             complement(14935..15867)
                     /locus_tag="NOA48_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789862.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="NOA48_001599"
     CDS             15984..17063
                     /locus_tag="NOA48_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0789863.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="NOA48_001600"
     CDS             17060..17689
                     /locus_tag="NOA48_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0789864.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="NOA48_001601"
     CDS             complement(17799..18026)
                     /locus_tag="NOA48_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0789865.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="NOA48_001602"
     CDS             complement(18129..20717)
                     /locus_tag="NOA48_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCI0789866.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="NOA48_001603"
     CDS             complement(20737..21396)
                     /locus_tag="NOA48_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0789867.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOA48_001604"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOA48_001604"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCI0789868.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="NOA48_001605"
     CDS             complement(22169..23035)
                     /locus_tag="NOA48_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0789869.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="NOA48_001606"
     CDS             23144..23785
                     /locus_tag="NOA48_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCI0789870.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOA48_001607"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOA48_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCI0789871.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="NOA48_001608"
     CDS             complement(25226..26125)
                     /locus_tag="NOA48_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0789872.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="NOA48_001609"
     CDS             complement(26127..26924)
                     /locus_tag="NOA48_001609"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCI0789873.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="NOA48_001610"
     CDS             complement(26902..27606)
                     /locus_tag="NOA48_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCI0789874.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="NOA48_001611"
     CDS             27737..28312
                     /locus_tag="NOA48_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCI0789875.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="NOA48_001612"
     CDS             28430..29107
                     /locus_tag="NOA48_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0789876.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaa
//
LOCUS       DAIGQM010000038        28055 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.038, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000038 DAIGQM010000000
VERSION     DAIGQM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.038"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..1350
                     /locus_tag="NOA48_001613"
     CDS             <1..1350
                     /locus_tag="NOA48_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0789877.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="NOA48_001614"
     CDS             1484..2827
                     /locus_tag="NOA48_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0789878.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="NOA48_001615"
     CDS             2939..4390
                     /locus_tag="NOA48_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCI0789879.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="NOA48_001616"
     CDS             4739..5371
                     /locus_tag="NOA48_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HCI0789880.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="NOA48_001617"
     CDS             5959..7398
                     /locus_tag="NOA48_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0789881.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="NOA48_001618"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="NOA48_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="NOA48_001619"
     CDS             8160..8375
                     /locus_tag="NOA48_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789882.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="NOA48_001620"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="NOA48_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9035..9946)
                     /locus_tag="NOA48_001621"
     CDS             complement(9035..9946)
                     /locus_tag="NOA48_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0789883.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="NOA48_001622"
     CDS             complement(9965..10969)
                     /locus_tag="NOA48_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI0789884.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNRSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="NOA48_001623"
     CDS             complement(10966..13089)
                     /locus_tag="NOA48_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0789885.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="NOA48_001624"
     CDS             complement(13094..15541)
                     /locus_tag="NOA48_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0789886.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="NOA48_001625"
     CDS             complement(15528..15917)
                     /locus_tag="NOA48_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0789887.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="NOA48_001626"
     CDS             complement(15977..16480)
                     /locus_tag="NOA48_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0789888.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..16714)
                     /locus_tag="NOA48_001627"
     CDS             complement(16493..16714)
                     /locus_tag="NOA48_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789889.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16719..16856)
                     /locus_tag="NOA48_001628"
     CDS             complement(16719..16856)
                     /locus_tag="NOA48_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCI0789890.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16853..18037)
                     /locus_tag="NOA48_001629"
     CDS             complement(16853..18037)
                     /locus_tag="NOA48_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0789891.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(18296..18586)
                     /locus_tag="NOA48_001630"
     CDS             complement(18296..18586)
                     /locus_tag="NOA48_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789892.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="NOA48_001631"
                     /pseudo
     CDS             complement(18576..19718)
                     /gene="dcm"
                     /locus_tag="NOA48_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19794..19958)
                     /locus_tag="NOA48_001632"
     CDS             complement(19794..19958)
                     /locus_tag="NOA48_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789893.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19951..20625)
                     /locus_tag="NOA48_001633"
     CDS             complement(19951..20625)
                     /locus_tag="NOA48_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0789894.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20703..22043)
                     /locus_tag="NOA48_001634"
     CDS             complement(20703..22043)
                     /locus_tag="NOA48_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0789895.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(22126..22461)
                     /locus_tag="NOA48_001635"
     CDS             complement(22126..22461)
                     /locus_tag="NOA48_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HCI0789896.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(22471..22845)
                     /locus_tag="NOA48_001636"
     CDS             complement(22471..22845)
                     /locus_tag="NOA48_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0789897.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(22858..23172)
                     /locus_tag="NOA48_001637"
     CDS             complement(22858..23172)
                     /locus_tag="NOA48_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0789898.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(23285..26512)
                     /gene="fss3"
                     /locus_tag="NOA48_001638"
     CDS             complement(23285..26512)
                     /gene="fss3"
                     /locus_tag="NOA48_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCI0789899.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(26929..>28055)
                     /locus_tag="NOA48_001639"
     CDS             complement(26929..>28055)
                     /locus_tag="NOA48_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789900.1"
                     /translation="SVRLYVRKDENGKQEYYVKKGFKTEKEAKLHEARKKVEIEDTGY
                     HKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFGNKSISKITPVHCQN
                     AVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPKREKKENENYFSLEE
                     LKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFEEQLMYVRKSYATIR
                     NEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQARELLQFGINTNTKN
                     QLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFRHTHATLLLEGGASI
                     KETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
BASE COUNT         8549 a         5593 c         4977 g         8936 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 gatttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattgg gcattggtta
    16681 aaaaccattg atataaattt tgtccgaaat tcatcttgtc actttccttt cttttccatt
    16741 gctcgatccg ctgctgcact tgcattcatc aagcacatca cagtaacacc aagcatactg
    16801 ccaccaaata ccaaaaaaat atcttttaca attcccatga cgattcctct tttcatataa
    16861 tcaaattttc aattgccata ctttgttgct ccaaaatctt tttatgtcgg tctgataagc
    16921 gtgcattctg taccatatcc tggatatagg ttgtccgatt caatcgatcc aactccttag
    16981 ccattttcca cgtaggggcg acttgtcggc ctagccaatt caaggttcgt tcaatggtat
    17041 acggttttgg ctcggaagtt aattgaatct ctttccgatt ccgtccaata aaacgccccc
    17101 attgttcatt caagggccag ttggttcgcc ttttaccttc tactttatcc gcaaatcgca
    17161 agtaacgatt gataatggaa aacgtggtgc tctcaatgct acgacctttt aacaaatctt
    17221 gaatcgcatg aaaagcacgg tcatttttca gtcgaatctc aaaacgattt ttcgtctcag
    17281 tttggtctaa tggaatccct aacttgatat attgttcata gtctttttca tacaaacaga
    17341 aataaacctc actcttgaga ctgccgatat ataaggtatt gcccatgccg tccttttcat
    17401 cagcctttaa aagttccccg gaacgataac ttttaaaggt acgaaacaag gagatacatt
    17461 cttccttctg acattttttc gttagctcag gtatatccaa tagccccact cgatcattga
    17521 ttgccaagtc caagcgtttc atcacgccac cggcctttag acaatcctcg aaaaagtcgt
    17581 accagctacg cttttgagcg agtaaaaaag tttcaaattg tcggcaacct cgccccttta
    17641 attctaaaag cacaccttta tcttcttcat gagacaacat caccacaata tcacccatga
    17701 catactgttc ttgataggag taaaaggcat aatcttcatg gagcatatac tcaaatttca
    17761 aatggagaat ttcttgaata atttttcgtg catccgttgt gggaaagcga atccttacat
    17821 agtcaaacag taacgtcaaa ggcaaatcgg gattaaagct ttccagttgg tcaaaaattt
    17881 tcctcatggt ttttatagat gcggttacgc caccattttc tatctgattt aagtacggcc
    17941 gactaagtcc acaagccgta gccaatttat tttgtgaaac gccgtattcg ttgcgtcggt
    18001 cttttaatag ccgataatct aaattccgtt gtgccaagtt ctcacctcca aattcaaggt
    18061 gttaactttt tcaaatgagt taacacctat acaaattact tactatcttt gatacaacaa
    18121 gcattcttaa tggttgctta cttatttttt gtgtttttgt acccccctgt tagatacggg
    18181 ggtgagacat catggtcggc taacgccgtc catgaacagg cacagcacca cggaggattt
    18241 ctgcttcgcg aatcctccgc ggtcagcgcc taacagtcag ttgtgttggt ttaggttact
    18301 catctgtaat accatttact tccaactctg ctttcatttc taacaagtat tgacgaatat
    18361 ctggttcttt tgcttggtcc gcaatccgct caaattctgc aattacttga tttatttcaa
    18421 ttcgagcatc cgtctcctca ttcattaaat atggatcgcc agcgactttg acaccattct
    18481 tgcgaatatc aaattttaac cgtcgcaatt gttcttctaa ttctgggtct gactgaatct
    18541 ttccaatcac ccaataaatt tctccaatca actcatcata aaccatgtac atccaactct
    18601 tttaatcttc tggcaatatc aaaaatgacc ggaactgtta cagagtttcc ggcttgctta
    18661 tacaactgac tatctgaatt gacttgagaa tctcgatcaa aagcccaatc gggaaagccc
    18721 tgaagtcgcc aacactctct aggtgttagc ttccgaattt gatactgatc cgtgacgatc
    18781 gcttgttggt ctcctgttag taaggtatga acactctgtt ttcccagacg acctcggcga
    18841 cttgtggaat taggaaaagc cagattcaca ctgtcttctg gcttcacctc ttgatattct
    18901 gtttcatttt ttcgaatcat gatttttgta ccaccttgtt tcgttgacaa ggtgggggcg
    18961 gttccagtaa cttcataaac tcgattacct tgttcaaact ttcccggtaa tagtcctgct
    19021 acagagattc catcccttgc tggcagtgcg attttgattc cttcatcacc tgttaaggtt
    19081 ggcgctacgc catctgaacc atagacttgt ccacccattc ctcgattgga aggattgata
    19141 tttaccaaat ttctgatgtt ttgatcagat gttgaagacg gtccaatgat aggaaatact
    19201 tgttcggtac atgcgtctcg agaatgtccg ataaggaata tccgctcccg gctttgggga
    19261 atgtaggcct ttgagttaag cacctaccac tccacgtcat accccaatcc atccagcgtt
    19321 cggaggatcg tctcgaacgt agcccctcct tcgtgattga gcaatcctcg gacgttctca
    19381 aggaataaaa gcttaggtcg gagaagagtg gtgaaccgag cgatttcaaa gaataaagta
    19441 cctcgagtat cggaaaatct ttgccgcttt cccgcaattg aaaaagcttg gcacggaaat
    19501 ccgccgcaaa ggatgtccac tggtccgagg gattgaataa actcatctga tacacttgtg
    19561 atgtcatgca tttccacctc cttacttgta tcatgaattg ctttataact acgtctagca
    19621 aatttatcaa tttcacaaaa accgatacaa tgatggctcg cctgttccat acctaaacga
    19681 aagccaccaa taccggcgaa taaatctaaa aatctcatac attacctcat tcattgcaaa
    19741 gaaaaaagcc aagaacattt tgctcttggc tcatacatta ttaatttgtc ctactatttt
    19801 ttatttaatc caactaattt ccgttgtttt tcattggcct gatcggctac atatttaatc
    19861 accgttttga actcttttgc agtagcattt tccgataaat ccgcaatgct cttattgtat
    19921 ttctttacaa ttttcgttac ttgttctttc tcagtcatgt aattgaacct ccaaatcttt
    19981 cctactatac cctagtggta aaaataattc tagattatcc gtagcataat gaacttcgga
    20041 aatattattc gtataatctt ttattatgat atgaagcaat acatctggat gtttactctt
    20101 tacttttgca atgttctctc ttgatttgaa aaaagcgtta ataaatgcct ttttcggcac
    20161 atgacgtccc tctgcaattt cacgttcttg tgtaaatttc caagcgattt tagggtcttg
    20221 ataaacatag aaaatcgtca ctcgaaaatg ttttttcaac gcccgcgaga tatttttttc
    20281 agcacttaat attgcaaaag ttgcatccag aataaaagaa tagccatgat ctaagacata
    20341 tctaaatgcc tgctctacca accaagaaga tgctttttga aagagactag agttttttcc
    20401 attataatca ggaaactggg tgcgaaagta atccgcatca ataatcacat ggttatcata
    20461 attctcagct aatccaatgg caacctctga ttttccagcc ccaggactcc ctgccataaa
    20521 aactgcgtct cgtccaactt cgggggattt ccctttgata atataagaaa taaacttatc
    20581 cttatttgct tttgcatact ctaaataaga atcattactt tccatattaa ttatcccctt
    20641 tcttcctact atataaaagt attatacgtt acttgaagta taaagtcagt attgaagatc
    20701 actcaatcat tcatcttttc taatttacta attgaatcta agaaatcata cccttttggt
    20761 acaagtggcg tataaaactc actaatcaca ctgccacctg tatccacata acctcgacct
    20821 ttgatgtgct tcataaagaa gtttttttcg acctccccaa acatcatgga atatccgagt
    20881 tcactcatac gacccaaagc cacgcgaaag ttgaattgat cgcggattcc gtctcctaaa
    20941 tatttcgcat ccggcctttg gcaagccaaa atcagaaaga aaccagattg acgacccaac
    21001 atcacgattt gtttgagctt attcaaaatc accgcacttt ctttcgtcgt taacatctcc
    21061 atataagcca cgtattcatc aaagattaaa aagttgggtg gaagtccaag ataggcataa
    21121 ttctctcctg ttttgtagtt agacatttct ttcattgcct tgctacgagc catcatacgt
    21181 tcatagaaat cttccacaca agcagaaatt tcttcctttt gtgaataaac atgaggcatc
    21241 accgtaccta aatcagctaa atctgcattt ttgggatcga ggataaacaa ttctgcatct
    21301 gacttcaata gtgcttcgat aatggtgagg aggaaatagg tcttccctcc acccgtgcca
    21361 ccagcgatta acatatgggg taaagaatca taagcccata cttgattttt catcaatcgc
    21421 agagtcccat tttctgccac tacttcgtct atcccaattc gattggcgat catatcatac
    21481 agtaaagtat actccacata ggagtctttg agttcctttt ctactaactc acaatacagt
    21541 ccgctttcta acttcttttc caattttaaa agctgatctt ggtatttccc aagtgaaatt
    21601 tgaacgcgaa tagacagtaa tccatctttc attcgataat agattttggg gaagtaactg
    21661 atagtctctc tggttcggct actattcaaa tctttgaaaa agccttcact ttgagtttgt
    21721 ttcacttcat accaatggtt ctctagaatc atccgagcta gcttttgtcg atgccacaag
    21781 cttcgccaat gatcaagaaa aaagtgaata taaagcaata tcatagctcc tgaaaaagcg
    21841 agacttccaa gcagacatac taaatctttt atagaccaaa cgatttcaat agtagaaagt
    21901 gatagcttag aaatatcaaa ttgtctaaac tcttgaaaat aaaagacgct catccaaccg
    21961 atgaacagag cgagtagcca gccaagaaca aagtgataaa ccaagtgctg atctcctgcg
    22021 cgtatgcgat gtcctttgta cattttgatg gtttccacct ccaatcgaaa aagcccaata
    22081 ggatttcatt aggcaatttc aaaaagttat gctagtcatt tactgctacg aggaggggag
    22141 ttgtttcgtt tcaaccaatt gatttaaaaa gccttcaata gcatccggca tctccacacc
    22201 aatttcttcc aaaatggatt ctgcctgccg acataagttt tcatttactt cgacaactat
    22261 aaagaaagac tcttcttctc ctaaccagtc tagtacatca gagtcttctt cactgtcgct
    22321 attttctcca agtaaacctt gatgtataat cagaaacatt ttttcatcag aggttaatgc
    22381 tttaacgagt tgttcctcag tcagctcgcc ttttccatat tgatcgagac aatctaaaat
    22441 atgttcaaca ttaatttcca taatcttcac ctatttcttt ctttcatttt ggttcgtagg
    22501 atttccttga ttcggctgcc gcttcaagac taaatcatcc gccttaatga accaattaac
    22561 ggtagttcct tctcgaaaaa cataattggc aacggtatcc acgattggat tgaccaactc
    22621 tacctctgca tcataagcaa actcgcgtaa gggtacatta gctgggatac taacttgaat
    22681 cattcgccct tgtgcagagg attttaaatt ataggttcgt tcttttacct cattaccaat
    22741 tgttccatcc tcattttgct tccgtacttc tcggcgtaat gcggaaaaac gcaacttccc
    22801 aaatgttaaa cctgaatcta cgacaatacc ttctgttaat ctcatcttct tttcctccta
    22861 tgctttcact aaatcatcaa catacaacac gtaatcagta aacccacgat tctcaatctc
    22921 atagcctttg gcaaccaaat ggggattcac ggcttttagc ggttggtctt gatcaaaatc
    22981 cttttcaccg gcttccgcag ctactaccac ctcaatatca tcggcccgtt gcttactgga
    23041 atacaaatga taactgcgac caatcaccgt agtattccgt ccatatcctt ctgttataat
    23101 ttctccttca ccggcataac ttaactttcc aaaggtttca gccatatctg gcacgacaaa
    23161 tttcaattcc atcttctttt cctcttttca ttgttagttt tggatacaaa aatagcgcga
    23221 ctactttttt aggaggcggt cgcgcacgtt ggttcttagg atttacttgt atcatctcat
    23281 caccttagtt ccggcgattc cagaaataat agcccgccgt cgcaaaaatc aaagtaaaac
    23341 caatgaacag taaaacattg gaatttttct ccccggtttg agggaaggtc ttcactgtgg
    23401 gactagattc ttgagagcca cttggaacag ttggtgtttc cggttgtttc ggcgtactta
    23461 gtatggttgg aacttctttt ggtgttaagg tttgagattt ttctttcaaa tcttcattgt
    23521 gttttccatt gatattccca tctttatcgt aattgatttc cgcaaaagta aacttggttc
    23581 cttctggata ttttccggta tctacttttt tcgcaagcac agttttggtg aattctttat
    23641 catttacttc ataatcaatc ttgccagatt tccaaatttc tttgtttgta ccatccggta
    23701 ataaagcata cagaattgtt tcgaaagctt cttttgagcc atccagtaca tcatgagtaa
    23761 tcgacacatc atcaaacata tccaccacat caccatgagt aaaggtctga gaaccgtttt
    23821 ctaggtgggc ctttgtttgg atagaaacat ggtgttccac tgtacaactg acagtttggg
    23881 cttggttatt caagctaaca tccttcgcta ctggcttatc gcctgcttca aaagcttcct
    23941 tattttcata cacatagttg aataagacaa tagttttatt taaaacttgt tcggcggtta
    24001 atttatgctg aattttccaa gttcctgttt tctctttgtt cgccaacgtt gcgcttgttt
    24061 ctgcaatcac cactggtttg gctttttcat ctttttcttg ggcagctttt gtcgcatcca
    24121 catcaatggc ttgcgctacc acataccagt cttctttgat ttcatgtaga ttgtaactca
    24181 atttatcaac tagctcggta gaatccagag aagttaattc tttgtttccg tctttccaag
    24241 tcgcaagaga agttaaacta tcttcttcct caggcaaatc atagagcatt aaacggttca
    24301 aactaacaga aaatgctttg ttcgtcagct tctcgtaagg aacggtcacc gttttaattg
    24361 gttgtttttg gtcttgttcg gtaatggtaa agacatactc actcttcaca aagtcttctt
    24421 tgttttcctt aaaagtagaa cggatttcta atggcgtaat cttttgaaaa ccttctgggg
    24481 cttctacttc ttcaagtaaa taatccccat aaggaagatt ttcaaacttg ccataaccat
    24541 caaaccctaa ttgctcgtta taagctgtgg tcgcttcatc ttcggcacct gtgatttcat
    24601 tggtcccttc caatggcgac actttaaagg tcagatcatt gaagccagtt tcggtagtgc
    24661 ccgcagctga tccagcaaat ttaaagaaat caaagccaaa gcgaatcact tgttcttttg
    24721 ccgtaacatt tcgggtaatc acggcatttt tttcgctatc atccaccttt ttgatggata
    24781 caggatactt tgtttcatca aggctatatc cttcgggcgc ttttgtttct tgccaataat
    24841 actcgttgat agctaaatgt ttaacggcaa cttggttctt ttcgtctaaa gtcaaagtga
    24901 ccgtttcatc agaacctttc gttcccttcg ctaactctgg tttaaaagcc tcactccatt
    24961 taacagcttt tccatcctta gcagtaaaca aggtgtattc agcaccctca aagactgcct
    25021 taccttgtgc tttatcccca gtatctttgt cttctttcgt caaagtggtt tcgccagtga
    25081 cttcttgatt ttgccctttt acgttactgg taacaagggc tacggtttga ttggcatact
    25141 tcaattcgac ttttacaggt ttgaacgtat tcacgaaccc atgactagct ttagtttcgg
    25201 tcacataata ggttcccaat tccaacgcat tagcaatctc ttttggtgtt tccgcatgac
    25261 cgttttcatc cgtggtcatt tcttgaacga tttcaccggt tggactgtct ttgcgaatgg
    25321 caaacgtatt accagctaag gaataattgt cattccaaag atcactccct gtttcaactc
    25381 cgcttttatc cagaatgatt tgcccttttt cccgtgcgtt ttttgaagtc acgtaaatgg
    25441 tttcgcctgc tttaatggtg gtagtcatgg gggtggtatc aatcgtataa ggcgccggta
    25501 ctgatttttc ggtaatggtt acttttgtac catgaggaat ctcatccaat gtagcaatgc
    25561 cttctttgtc agtagtcacg tcttttgcag gtaaagtttt tccaaagtct aaatggaaaa
    25621 ccgttcctgg tacaacatca cccgattctt tatcgacttt tttgatcttt aaagaaccct
    25681 ccgtttccac atcaattttg attgtgtagg tattaggttt atcaatcgcc ccggccatta
    25741 aagtctgttg gccagccttt ttataggcga caggtgttcc ggtaccagca gatttcttaa
    25801 gcgtcagcac accactttct tttgaattgg catttggggt gattatcaac tgattaccat
    25861 tcacacgata atcaatgttt gcggcatttt ccacaacctc atcgaactct gacaaattca
    25921 gattattcgt atccgtcaca gtagtcgatt gccctaatac tgttttagcc gtactattat
    25981 ggaaggttgg tttcttctga taatcgtcaa tggcttgatt tatttttgcc tcaatggctg
    26041 cgatatttac ggcactacca tctgatcgtt ttattgagtg aagggtatac ccattaactt
    26101 cttgccagat catcttctgt gccacaatat gagtatctgc atctgtacct acttttttcc
    26161 ataaaacgga aactaatttg gctttatcgg acatatctgg taacgggttt ttctcatagc
    26221 caggagtgaa ctcattgtaa atcgggactc ctggttcaat acagaaaata tcttgtttaa
    26281 agccgttgta cactgcataa tgcggaacag tgacttctga cattggacga ccatcactaa
    26341 aagttccttc aacagcatat tgatgtgcta aatctagttc tacggttacc gtttgtggat
    26401 gggtaatttc atcagcaaaa gtaatcgtag gagcaattgc tccaacaatt gcttgaacag
    26461 ccaaactcaa aatagttaat acacataatt tctttttttg ttttttatac atgaaatgtt
    26521 ctcctttcaa attaagcaca aaaaaataag atgctcgctt gaacatcttt gtttataaag
    26581 tctttttaaa atttttattg actgaataga atggatttga gaatgaatga gcctaaaaat
    26641 ttaatctaaa atacgaaata tactgccttt aaattagaac acattttaga acacaaacat
    26701 ttcaaattta atcaaatata ataaaatata tttacgggaa aacctttata aatcaaggtt
    26761 tttcaaactt attcaatgat acgaagaaaa aaccaggtct taagaaagca cgtaaagctt
    26821 cacagttttc aaaacgttaa tcgttgttat accaacgatt tcagacactt tctcattgcg
    26881 agaaggtgtc tttttttcgt tctggtaatg agaaaggtaa tgacaatatt ataaaccagt
    26941 gtaagcaatg aatttttcta acgcatttcg ttgagctttt tcagtaacat gagaataagt
    27001 gttaagggta gtttcagcat ttttatgacc caatcgatct tgtgtttctt tgatacttgc
    27061 tccaccttct agtagaagag tagcgtgagt gtgccggaat ccatgaatag taacgtgctt
    27121 aaatttatat ttcttctcta aacgtttcaa tatattattt gaatagtccg catgcaaagg
    27181 ttgattaatg tcaccgtctg catttacata ggtaaagata agttgatttt ttgtatttgt
    27241 atttatgcca aactgcaaaa gctctcgagc ttgttctttt ttccagattt ttaacatttc
    27301 aatagtttgt gcatcaattg gtaatattcg ttcggaagat atattttttg tatttttttg
    27361 aatcctgaca gtttttcttc ttgcattctt ctcttcattt cgaatagttg catagctctt
    27421 tctaacatac attagctgtt cttcaaaata aatgtcagac caatgaagag cagctagctc
    27481 tcctttacgt ataccagtag taatcaaaag ctggaagatt aaaatatgtt ttaaaggctc
    27541 ttctttattg agaatatccc aaaaagcttt tagttcttct aatgaaaagt aattttcatt
    27601 ttctttcttt tcccgctttg gtagatttgt atttgccata ggatttcggt gtaatagctc
    27661 tgcaaaaatg gcatactcaa atatttgaga gctgtaagac ttaagctgtt tgatattctt
    27721 gaattttaaa gcccattcat tgactgcatt ctgacagtga acaggagtaa tcttagaaat
    27781 ggacttattc ccgaattttg gtagtatatg caagcggaaa aggtcttttg tacgttgata
    27841 tgtcgtttct tgtacacgat tcctataaga aggcaaccat tcttcataca ctgttataaa
    27901 caagtcatta gaaggcttat gatagccggt atcttcaatc tcgacctttt ttcttgcttc
    27961 gtgtaacttg gcttcttttt cagttttaaa cccttttttt acatagtatt cttgctttcc
    28021 attttcatct ttacgaacat acaagcggac actat
//
LOCUS       DAIGQM010000039        27380 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.039, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000039 DAIGQM010000000
VERSION     DAIGQM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.039"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            154..384
                     /locus_tag="NOA48_001640"
     CDS             154..384
                     /locus_tag="NOA48_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCI0789901.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            481..1782
                     /gene="murA"
                     /locus_tag="NOA48_001641"
     CDS             481..1782
                     /gene="murA"
                     /locus_tag="NOA48_001641"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0789902.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1795..1971
                     /locus_tag="NOA48_001642"
     CDS             1795..1971
                     /locus_tag="NOA48_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0789903.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2106..2402
                     /gene="yidD"
                     /locus_tag="NOA48_001643"
     CDS             2106..2402
                     /gene="yidD"
                     /locus_tag="NOA48_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCI0789904.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2586..3053
                     /locus_tag="NOA48_001644"
     CDS             2586..3053
                     /locus_tag="NOA48_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789905.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3138..4022
                     /locus_tag="NOA48_001645"
     CDS             3138..4022
                     /locus_tag="NOA48_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0789906.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4136..4372
                     /locus_tag="NOA48_001646"
     CDS             4136..4372
                     /locus_tag="NOA48_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCI0789907.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4460..4540
                     /locus_tag="NOA48_001647"
     tRNA            4460..4540
                     /locus_tag="NOA48_001647"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4494..4496,aa:Tyr,seq:gta)
     gene            4547..4618
                     /locus_tag="NOA48_001648"
     tRNA            4547..4618
                     /locus_tag="NOA48_001648"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4579..4581,aa:Gln,seq:ttg)
     gene            4743..4913
                     /locus_tag="NOA48_001649"
     CDS             4743..4913
                     /locus_tag="NOA48_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789908.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5133..5840
                     /locus_tag="NOA48_001650"
     CDS             5133..5840
                     /locus_tag="NOA48_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0789909.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5900..6544)
                     /locus_tag="NOA48_001651"
     CDS             complement(5900..6544)
                     /locus_tag="NOA48_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCI0789910.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6671..6958
                     /locus_tag="NOA48_001652"
     CDS             6671..6958
                     /locus_tag="NOA48_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789911.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7066..7386
                     /locus_tag="NOA48_001653"
     CDS             7066..7386
                     /locus_tag="NOA48_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0789912.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7467..8780
                     /locus_tag="NOA48_001654"
     CDS             7467..8780
                     /locus_tag="NOA48_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0789913.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8777..9496
                     /locus_tag="NOA48_001655"
     CDS             8777..9496
                     /locus_tag="NOA48_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCI0789914.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9624..10175
                     /gene="raiA"
                     /locus_tag="NOA48_001656"
     CDS             9624..10175
                     /gene="raiA"
                     /locus_tag="NOA48_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCI0789915.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10397..12931
                     /gene="secA"
                     /locus_tag="NOA48_001657"
     CDS             10397..12931
                     /gene="secA"
                     /locus_tag="NOA48_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCI0789916.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            13058..14159
                     /gene="prfB"
                     /locus_tag="NOA48_001658"
     CDS             join(13058..13129,13131..14159)
                     /gene="prfB"
                     /locus_tag="NOA48_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCI0789917.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14264..14950
                     /gene="ftsE"
                     /locus_tag="NOA48_001659"
     CDS             14264..14950
                     /gene="ftsE"
                     /locus_tag="NOA48_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCI0789918.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14934..15827
                     /locus_tag="NOA48_001660"
     CDS             14934..15827
                     /locus_tag="NOA48_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789919.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15979..17427
                     /gene="cls"
                     /locus_tag="NOA48_001661"
     CDS             15979..17427
                     /gene="cls"
                     /locus_tag="NOA48_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI0789920.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            17764..18621
                     /locus_tag="NOA48_001662"
     CDS             17764..18621
                     /locus_tag="NOA48_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCI0789921.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18736..19656
                     /gene="pstC"
                     /locus_tag="NOA48_001663"
     CDS             18736..19656
                     /gene="pstC"
                     /locus_tag="NOA48_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCI0789922.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19656..20540
                     /gene="pstA"
                     /locus_tag="NOA48_001664"
     CDS             19656..20540
                     /gene="pstA"
                     /locus_tag="NOA48_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCI0789923.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20555..21361
                     /gene="pstB"
                     /locus_tag="NOA48_001665"
     CDS             20555..21361
                     /gene="pstB"
                     /locus_tag="NOA48_001665"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0789924.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21377..22135
                     /locus_tag="NOA48_001666"
     CDS             21377..22135
                     /locus_tag="NOA48_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0789925.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22148..22825
                     /gene="phoU"
                     /locus_tag="NOA48_001667"
     CDS             22148..22825
                     /gene="phoU"
                     /locus_tag="NOA48_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCI0789926.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23047..24081
                     /locus_tag="NOA48_001668"
     CDS             23047..24081
                     /locus_tag="NOA48_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI0789927.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            24078..24845
                     /locus_tag="NOA48_001669"
     CDS             24078..24845
                     /locus_tag="NOA48_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI0789928.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            24945..26513
                     /gene="liaX"
                     /locus_tag="NOA48_001670"
     CDS             24945..26513
                     /gene="liaX"
                     /locus_tag="NOA48_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCI0789929.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26689..26997
                     /locus_tag="NOA48_001671"
     CDS             26689..26997
                     /locus_tag="NOA48_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCI0789930.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            26997..27347
                     /locus_tag="NOA48_001672"
     CDS             26997..27347
                     /locus_tag="NOA48_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCI0789931.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         9041 a         4669 c         5937 g         7733 t
ORIGIN      
        1 cagtcccttt ttttgcatat ttttagcatt tatttcctaa aaaatgtaag gggattccta
       61 tatttttaag tatacttgtt tttcctttta tacattttat ggtattatca ttttattagt
      121 tattataaaa caatcgttag aaaggacgtc attatgcaag tatacggaat tgatgcggtg
      181 cttcgaatcg tgagtcattt ggcgtttatc tacttagcct tctggtcttt acgttcgtta
      241 cgcattgaaa cttttttcag accaatgcat aatacgcaaa ttagaatggc aatcgtactt
      301 ttttcaattt ttttagggta cactgcaagt aattttttct tagaagttat cgctttatgc
      361 cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta ctattttaaa agcaaggatg
      421 ttataataga aaagattttg agtaagtgta tgctcattgg aattttttgg agggaacaac
      481 atggaagaga tcatcgtaag aggtggcaat caattaaatg gaacagtaag aattgaagga
      541 gctaaaaatg ctgttttgcc tattttagct gctagtttgt tagcagaaga aggtattacg
      601 acattagaca acgttccgat tctttctgat gtcttcacta tgaatcaagt gattcgtcac
      661 ttaaacgtag atgtagattt tgatgaacaa aagaatcaag taacaatcga tgcttcaaga
      721 caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa tgcgtgcttc aatcgttgtg
      781 atgggtccgc tacttgccag aaatggacat gcaaaagtag ctatgcctgg tggatgtgcg
      841 attggtaaac gaccaatcga tttgcattta aaaggatttc aagctttagg agcaaaaatt
      901 attcaaaaaa acggctatat cgaagcaatt gcggatgaat tgatcggtaa cacgatttat
      961 ttagatttcc ctagtgtagg tgctactcaa aatatcatga tggctgccgt aaaagcaaaa
     1021 ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa tcgttgattt agcaaacatt
     1081 ttgaataaaa tgggcgctca agtctatgga gctggtactg aaacaatgcg tattgaaggc
     1141 gtggatcatt tacatgcagt caaccactca atcgtacaag atcgtatcga agcaggtacc
     1201 tttatggttg ctgctgcaat gacacaaggc aatgtgctga ttgcagatgc tatctctgaa
     1261 cataaccgcc cattgatttc taaattgatc gaaatgggtg cagaaatcat tgaagaagaa
     1321 ggcggagtcc gtgtcatcgg accaaaacat atcttaccta cagatgtaaa aacgatgcct
     1381 catcctggtt tccctacaga tatgcaagct caaatgacag ctatccaatt agttgcagaa
     1441 ggtacaagtg tagtgactga aacagtgttt gaaaatcgtt tccaacattt agaagagatg
     1501 cgccgtatga acgctcatgt caaaatcgac ggaaatgtag caatcatgga tggaaaccat
     1561 gaattgcaag gtgcagaagt atatgcaaca gacttgcggg cagcagcagc attagtttta
     1621 gctggcttga aagcaaatgg aatcacacgt gtgcgtaact tgaattatct agaccgtgga
     1681 tattataatt tccatatcaa actacagcaa ttaggtgcag acgttgaacg tgtagacatg
     1741 gatcaaactt ctgctgaaaa aacagcacaa acgattgctt aaggaagtgg ctgaatgagt
     1801 aaccaacgat atatcttatt aactttgata aagattttag tggtgatctt attgcttatc
     1861 cttctttttg tggccggaac gatgatcgga tatggtgtca tcggtggcgg caatccattt
     1921 aaagtattcc agccaagttt gtggattcat attcgagact tttttcattg ataaataaga
     1981 atcacagtgg ttctagtcga tatgaagtga gccatgaagc agaacatgac aaaagaaaac
     2041 agaagggaac gttgacgtta gtcgcgatcc ctttttttag taaaagaaaa gaaggaatct
     2101 aattgatgaa gaagatattg atttatttag ttagaggata tcagcgcttt atttcgcctg
     2161 catttccacc tagctgccgt tattacccaa cctgttccaa ttatatgata aaagcaattc
     2221 aaacccatgg tgcactaaaa gggacggtaa tggggactgc acggatctta cgctgtcatc
     2281 cttttgtcaa aggcggtatc gattatgtac cattgacatt ccaattaacg cgaaataaga
     2341 aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa tacgagtagc actgagcgat
     2401 aaagaaacaa tttggaaaat agcttcttat attttgcaaa attgtgagtt attgccgaag
     2461 tgttggattt tgaacaccgt caaaaaaagg ttgtgaaaaa tacgggtagc actgagcgat
     2521 aaagaaaaag aggaaaatta ttgtcaaagt aacaactccg caactactta tatgggggac
     2581 aaaaaatgat cgaagaacta aacaagaaag atttaccatg gtccttgtta ttagatgcag
     2641 atcctgataa agaaaaagtt caagtatatg tttccagagg gagtggctgg atatggaaag
     2701 aaaaagaaaa aacaataggt gtactgatct atgtggcaag ggaaaaagaa tacgaaatcg
     2761 tcaatgtagc agtagcccca acgtatcaag gaaaggggat tggcggaaaa ttacttgaga
     2821 cagcttttca gaagctttca caactcgctt ccagtcaaac tcagatcatc atacgaaccg
     2881 gcagtactag cagtgcggcg ttacatctct atcaaaaaat gggctatgtg gagattggtc
     2941 gagtcaaaga ctattttatc catcattact ctgagcccat ttttgaaaat ggagatcaat
     3001 taagggatca agtaatttta gcaattcact tacctaaaaa tagctttaac taataaactt
     3061 tcaattcgag aaaatgcttt caaatgctaa atagatacat tacaatagct ttagcaaaca
     3121 aaaaggagaa tatttttatg ggaatattag tttttgattt tggtggatcg gctgtcaaat
     3181 atggttgttg ggatggcaaa gagattaaag gtaagggaca atttgcaacg cctgaatctt
     3241 gggaagaaat gaaagcgcaa ttatttcaag tttataaaaa aatactcgtt tcttttgaag
     3301 tcgaaggaat tggaatcagc tctcctggag tagtgaataa tgagaaacag gtgattgagg
     3361 gaatcagtgc gattccttat attcatggat ttaatatttt ccgagatttg gaaactctgt
     3421 ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc cggaatggct gaattttatg
     3481 aaggtgctgc ccgtgattat caagatgttg cttttgttgt ggcaggaact gggattggcg
     3541 gggcgttgtt cacgaaagga caaatcaata aaggggcaca tctttatggt ggagaatttg
     3601 ggttgatgtt cttaaatggc gataagacat tcagtaaact tggtacagcg gtacagatgg
     3661 cttggcgtta ttgtgaacgc aaaggtctcg ataaaaattc ttataccgga aaagatgtct
     3721 ttgaattagc agaaactgga gatgcaatag caaaagaaga agttgagagt ttttatacgt
     3781 atcttacaaa gggattattc agtattcaat tttcgtttga tccagaagtg atcgtattag
     3841 gcggcggtgt ttctgcaaaa gaagggctca ttgatgagat caaaagccga atgaagaagc
     3901 tgacagaaca attcgatctg catgatttcg aaccgcagat tttattatgt gaatacagaa
     3961 acgatgctaa tcttgtaggt gcagcagcaa actatctcgc tgtacgtcaa ggggagaatt
     4021 aagagcttta gagaaggtgc agcttgcata aaagaagtga atgaaatgaa taggagattt
     4081 ttacctaagg aatgttttat ttgctgcagt atgataaaat atctgagagg tgaaaatgat
     4141 gtcaaaaaaa aataaagatg ttgaagtgcg tatagaagaa gtgaaaaaag atatcaaagg
     4201 taagaattat gaagtcactc agttatttat agggaaaaaa atgattggtg agatcttagc
     4261 ctatgggcca aaagaatatg aaattttctt tggtgaagaa gattttggaa aagaaaaaag
     4321 tcttgaaaat gcgatagaaa cagtgattcg acactggaat ctgcacgaat aaaaaaatat
     4381 caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa ttaggtatta taactaagtc
     4441 aggttgatac aaacctttcg gaggagtagc gaagtggcta aacgcgacgg actgtaaatc
     4501 cgttccttag ggttcagtgg ttcgaatcca ctctcctcca tttcattggg gtatagccaa
     4561 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagta
     4621 taccacaatc gtaagctctc gttagttcga gagctctttt ttttgctttg ctaccttgtt
     4681 ccttgaagat tctgctgatt taagatagag ttaagttaac tacaagaatt ggagggatcc
     4741 acatgaaatg gaaagaaaaa gtagacgaag cagctgaaaa gttatatgat ttggtcaaat
     4801 cagaaaaata caatattgaa gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa
     4861 aatcaaaacg cccaacgaat catacaaaaa aatggatggc taaaaaccgc taataataac
     4921 aaaagatcca taagtcggca ttttcatcga ttttagggtc ttttgttatt ttctaggttg
     4981 aacatatcta aaaaattgtt tctgacaata ggagtaggaa gaacgatgtg tgtctaaatc
     5041 ctctgttgat ggatagaaac ctttatcttt ttcagttgtg aatcaggtat ataccagtta
     5101 taatagaaga aacgaaagga cgggtgtacg ttatgtcgaa tcaattacct gtatatatac
     5161 agattcatga ccaattaaaa aatgaaatcg aacaaggtat atggaaagtc ggagaccgtc
     5221 ttccttcaga aagagaatta gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag
     5281 caattcaaaa cttggcagat gaaggaatct tagaaagaaa gatcggttcg ggtacatatg
     5341 ttgcgcgaga aaaagtacaa gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg
     5401 aatcgcaaaa tcgagtaccg tctagtcgga caatctctta tttcttgact tcgccaagct
     5461 caagtgaaat ggaaaaacta aacttgagta aagatgacac gatcttgcga atggaacgta
     5521 ttcgtttcgc agatgatgtc cctatttgtt ttgaagttgc cagtgtgcca caaaagctga
     5581 tcgatggcta cagcaaagca gagattactg aatcgttgta tcgcacgcta gaagaaaaag
     5641 gcgggaaaaa gatcggtcca gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa
     5701 ttgctgacta tttagaggta aaacgaggag atgcagttct tcgtttgcgc cagatttctt
     5761 attttgaaga cggtacgccg tttgagtatg tgcgtacgca atacgtagga aatcgttttg
     5821 agttttattt ggaaaaataa aaaacaggtg atccctgatt ccttacttag aaataaaaga
     5881 gaatcagaat cacctgtttt tatatatgat cagttaccag ttgctcgtga taagaaacag
     5941 gaccctcttc aaattggact tgtccgttca gcagctcaat gatggattct ttaaagtggt
     6001 cagcactttt ttcatctaca gcacagatga cgctaacttg atcagtatat tggatttctt
     6061 ttataaaaaa atgttggagt tcaagataat tctgtaattt tcctagttgc ggatacgtga
     6121 tcatcacaga gatctcctgt tgcaaggtac cttctacgat tccaatgtca gacaatgctt
     6181 gagagacagc atgagtgtat gctcgtatta atccgcctgt gccgagtttc gttcctccaa
     6241 aatatcgagt gactactgca gctacattga tcagttgatt ttttttgagg acttccaaca
     6301 tcggtacgcc agccgttcca cttggttctc catcatcgct gcttcgctgg atttcatttt
     6361 tttctccaat gatgaaggcg ctgcagttat ggttcgcttt ccaatgttct ttttttattt
     6421 cttgaatgaa actttttgct tggtcctctg attctattcg tctaagagaa cagataaagc
     6481 gtgatttttt gatctcaatc tcactttgtc cattttcttt tattgtacga tagcgctcga
     6541 tcatcttgtc acctcttttt ttcattttct ttattcagta taaataaagt tctaggttgt
     6601 ttcaacactg taacggttgc gcaatcgctg tagtatgcga taataaagac aaaggtaggt
     6661 ggatctgggg atgcaggaac gaatgaaaaa gtacgatgca attacgcatt atttgaagaa
     6721 caatggcggc tctcaagtaa cgttgacctt tacccaattt gacgaactgc tgtttcccag
     6781 taacggactt cccaaaacag caagggaaag tacagattgg tgggcaaatg attataaaca
     6841 ccctgaaaaa ggtgcctatg gctggataaa tgcaggctat gaagtagttg tcatcaattt
     6901 ggacaaagaa tatgtcgtgt tcaataaatt agtgaaatct agttggctat ttgattaaat
     6961 aaaccgcgtt tagaaaacgt tgacaaattt ctttcttttt atataataga gtaacagacg
     7021 cgaagaaaac gtttgcgtag tttgttttaa aaaggagaga aaagtatggc taaaaaaaca
     7081 atcatgcttg tatgttcggc tggtatgagc acaagtttac tagtaacaaa aatgcaaaaa
     7141 gctgctgaag caaaaggaat cgactcggat attttcgctg tgtccgcttc tgacgcagat
     7201 aacaatcttg caaataaaga tgtagatgta ctgttattag gacctcaagt tcgctttatg
     7261 aaagctgatt ttgaaaaacg tctggaacca aaaggcattc ctttagacgt catcaatatg
     7321 gctgattatg gtatgatgaa tggcgaaaaa gtgttagatc aagcaatcac gctcataggt
     7381 gaataaatag aacagtataa ctatcgaaca agcgatccaa aaaatagatc gcttgttttt
     7441 tcgtatattt ttttagggcg aataatatga atcatttttg gggtagaagg cttctgacga
     7501 gagatattaa agcaatagac tgtgaggagg taaatttacc aaattatgag aagatcgcag
     7561 cagtggaacg tttgggcaac tggattcttt gtcatcgctg tggaatgagg acgtccgtca
     7621 ttgatggaca gcttgcagat tacggttatt tttgtacaca ttgtctatat ttagggcgat
     7681 gcgacactca acaagattta tatttgtttg atcagcctga agcaaaacct cgagaagtcg
     7741 tctttttttg gacaggacag cttactgaaa aacaaacgga aatcgcaaag agaatacttt
     7801 gccattcaga aaaaagacat catcttattt gggctgtaac aggtgcaggg aaaacagaga
     7861 tgctttatcc tattttagtg gaaactttaa aagctggagg aagagtagcg atttgtacac
     7921 cgcgagtcga tgtttgtaat gaattgtttt tacgctatcg ttatgttttt ccagaagaaa
     7981 aaatcacgtt gctccatggg aatacagcaa cggcttatac ctttacttct tttgttatct
     8041 gtacgattca tcagctatac cgtttttatc ggtcctttga tttaatagtg atcgatgaga
     8101 tcgatgcgtt tccttataac ggggatgcag gattagctca tgctgtgcaa acagcgatta
     8161 aaccagacgg acgattcatc tacttaagtg ccacacctga taaaaagtta ctaaaggaaa
     8221 tcaagcagac gtttgacatc cacaaacttg ctttgcgctt tcatcggcgt ttacttcctg
     8281 aacccgtctt ggttttcatg aataattggc gacaaaaatg caagaacaag aagaagataa
     8341 aatctttggt gcggatcatt catcaattaa ttaaagaaaa ccatatcctt ttattttgtc
     8401 caagtatcac gatgatgcat cgtttgaaag ccacacttca agaggctctt ccgagatatg
     8461 agatcacaga tgtttcttca agagacaatc agcgggcgga aaaagtccag aaaatgcgag
     8521 aagcaaaata tgacatactg ttaaccacga tgatccttga acgtggagtc acatttgaaa
     8581 gaatatccgt tatcgtttta ggagcggatc atccggtttt tactaaatct tctttggtac
     8641 aaatcgcagg aagagccgat cgtaaagggc cttatacgaa cagtcaagta tactttttct
     8701 atgaagaaaa aactgcagct attcgaaaag cttgtcagga aatcaaagaa atgaatgaag
     8761 aagggaagaa gatgctgtga ggtgcagttg ctgcagtaaa gatatcgtcc aaaatttaac
     8821 attcagcgag attattggtg tttcgaaata cagattacct cagacttgtt cagtttgtcg
     8881 cgcacaattt catttattgg aaacaagagg ctgttctggc tgtcaaaaac caatccattt
     8941 caatctagag agtacgaaaa agaaagtaaa gtctattccc gtttactgca gtgactgtca
     9001 agaatggaag aagaaatatc cgacctatga ttttcagcac cgtgcctttt ttgtgtacga
     9061 tgaaaatatg aaggcctggc tcaatcaata caagtttatg ggagatatcc gactagcagg
     9121 cacctttgca tataaatgga cgcagataaa aaaagaatac ccgacataca tctattgtcc
     9181 aataccttta tctgaaaaaa ggcgaacaga aagaggattc aatcaagtaa gcgagatgtt
     9241 gaaagcagca agaattcctt ttcagatgct actcaaaaga gagaagcatc tgctggctca
     9301 agcaaaaaac acgcgaaagg aaagattgga gatgcctcaa ccttttgaac ttgcagtcac
     9361 cttttctaag atacaaaata aaaaaatatt gattattgat gatgtctata caacaggaca
     9421 gactcttttc cacgcagcag attgtttgca ggtcgcacag ccgaaaatca tccgaaccat
     9481 ttctttagca agatgaatta gatgtggaaa tttgatagcg atttaatttg caaataacct
     9541 agagttcgat ataatagaat taagaagagg gaaagagtgg tccttctcct tcttgattgt
     9601 ggtagacgaa aggggtaatt tttatgttta gatataatgt acgcggcgaa aatatcgaag
     9661 taactgaagc gattcgcgac tacgttgaga aaaaagtagg caaactagaa cgctatttca
     9721 gtgacgcacc cgatgcaacg gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa
     9781 aagtggaagt aacgatccca ttaccttatc ttgtattacg tgccgaagaa acttctccag
     9841 atttatacgc aagtatcgat ttggttgttg acaaattgga acgccaaatc cgcaaattca
     9901 aaacaaaaat taatcgtaaa tcccgtgaaa cgggcatgaa tactgcagat gctactgctt
     9961 tattcaatga agaggacgaa aacgaaaatg attctgaatt agatatcgta cgtacgaaac
    10021 gcctttcatt gaaaccaatg gatagtgaag aagcagtctt acaaatgaac atgctgggac
    10081 ataacttctt tatttttgaa gatgcagaaa caaatggtac aagtatcgtt taccgccgta
    10141 aagatggaaa atacggactg attgaaacag actgatcagc cttacttaaa taacaacgaa
    10201 aacttgcagc agctactgac agctgccgca agtttttttg agtttcctcc tcttttagat
    10261 gaaatatgaa taaattatga agttcttact ttaatacgct taagatattt caattatcta
    10321 taactaatga taaaatgaaa agtaaagtct acatagtctg gataatacac agaaggaaaa
    10381 ggagattaca caacgcatgg ccaatttgat tcgttcactt atcgaaaacg ataagaaaga
    10441 actaaaacgt ttagatagca ttgcaaaaaa agttgaagca tacgctgacc aaatggcagc
    10501 attaactgat gaacaattac aggcaaaaac tgctgaattc aagggcagat accaaaaagg
    10561 agaaacatta gatcaattac ttccggaagc ttttgcagtc gtccgagaag cagcaaaacg
    10621 tgtattgggg ttatatccat accacgtaca attaatgggt gggatcgtgc ttcacgatgg
    10681 gaatatccct gaaatgcgta ctggtgaagg taaaaccttg actgcaacga tgccggtgta
    10741 tctgaatgcg ttgactggcg aaggggtcca cgtagttacc gtcaatgaat atttagcaac
    10801 ccgtgactcg acggaaatgg gcgagcttta taatttctta ggattgacag ttgggttgaa
    10861 tatcaactca aaatcttcgg atgaaaaacg cgaggcttat aattgcgata tcacttatag
    10921 cacgaataat gaattaggat ttgactattt gagagacaac atggtcgttt accgtcatca
    10981 aatggtacaa cgtccgctga attatgccat tgtcgatgaa gttgactcga tcttgattga
    11041 tgaagcgaga acgccgctga tcatttcagg gcaagcagaa aaatcaacag ctttatatac
    11101 aagagcagac aacttcgtga aacgtttgaa agaagaagaa gattataaaa tcgatataca
    11161 atcaaaaaca atcagtttaa ctgaagcagg gatcgaaaaa gctgaagaaa cattcggttt
    11221 ggacaactta tatgacattg aaaatactgc attgacccat cacttggatc aagcattgag
    11281 agccaactac atcatgcttt tagacatcga ttatgttgtt caagatggaa aagtattgat
    11341 tgttgaccaa tttacgggtc ggatcatgga tggacgccgt tattcagatg gtcttcatca
    11401 agcgatcgaa gctaaagaag gcgtagagat cgaagacgaa acgaaaacga tggcgacgat
    11461 cactttccag aactatttcc gtatgtacaa gaaacttgcg gggatgactg gtacagctaa
    11521 gacagaagaa gaagagttca gagagattta taatattcaa gtataccaga ttccgacaaa
    11581 ccgtccggtc atccgtgacg atcgaccaga tttgctttac ccaacattac aaagcaagtt
    11641 ccatgctgtc gtacaagata tcaaagatcg ctaccgcaaa ggacagcctg tcttagtcgg
    11701 aactgttgca gttgaaacat ctgagttatt atcagatatg ctgaatcaag aacgtattcc
    11761 tcatgaagta ctgaatgcga aaaatcactt taaagaagca gaaatcatca tgaatgcggg
    11821 tcaaaaaggt gcagtgacga ttgctaccaa catggctggt cggggaacag atatcaagct
    11881 agggcttggc gtaagagaac ttggtggcct agcagttatc gggacagaac gacatgaatc
    11941 tcgtcgtatc gataaccagc ttcgaggacg tgcaggacgt caaggagacc ctggtatgtc
    12001 acaattctac ttgtctttag aagatgattt gatgaaacga ttcggttcag aacgaatcaa
    12061 agctttctta gatcgaatga agatcggtga cgaagatgct gtgatccaaa gcaagatgct
    12121 gacgaaacaa gtagaagctg cacaaaaacg cgtagaagga aacaactacg acacacgtaa
    12181 gaacgtcttg caatacgatg acgtgatgcg tgagcaacgt gaagtaatct ataaacagcg
    12241 tcaagaagtg atcatggaag aaaaaagctt atctaaacca ctgatgaata tggtcaaacg
    12301 gacaatcagt cgtgtggtag atgcgcatac gcaattagaa aaagaaaatt ggaatttgga
    12361 aagtatcgtc gattttgctg gcagcacgct tgtccatgaa gacagtattt cccttacaga
    12421 tatcgaagga aaaacctctc aagaaatcaa agaatatcta aacgaacgag cacaagaagt
    12481 attcaatacc aaagcagctc aattgaacgg accagagcaa ctgcttgaat ttgaaaaagt
    12541 cgtgatctta cgtgtcgtgg actctaaatg gacagatcat attgatgcaa tggaccaatt
    12601 acgtcagtca atcggcttgc gtgcctatgg tcaaaacaat ccattagtcg aataccaaac
    12661 agaaggttat aagatgttcg aagatatggt aggtgccatt gaatatgaag tcactcgtat
    12721 cttcatgaaa gctgagatcc gtcaaaacgt acaacgtgag caagtttctc aaggaacagc
    12781 ttctcactca gaagatggag atgccaaaga aaacagtaat actagcgcga aaaaacaacc
    12841 aatccatgtg aacaaggttg gtagaaatga tccttgtcct tgtggaagcg ggaaaaaata
    12901 taagaactgt cacggaaaag atgcaaacta atttctgaca gcaggattgg tgagacaaat
    12961 tcttttttaa agaatttgtc tcaccttctt tctgttattt gacgattctg ttagactaga
    13021 tataataaaa aaagtatagt gaaagaagga aaaaaacatg gaaatatccg aaattcgaaa
    13081 tctcctgaca gaaatgcagg aaaaggtcac aagcttcagg aggtctcttt gacttagacc
    13141 agctggaaga agacattgcg gaagcagaag caaaaatggc tgaacctggt ttttgggatg
    13201 atagcgaagc tgctcaaaaa gtgatcagtg aaaacaatgc aaataaagaa acttatgatc
    13261 aattccattc tcttgctgaa gaactggaag aaatcgaatt gatggtggag atgttgcagg
    13321 aagaacctga tgcagtaatg caagaagaag cagaagcacg tatcaatgcg ctagatgaaa
    13381 aaatgaatac gtatgaatta tctatgttgt tagatggtcc ttatgatcga aacaacgcca
    13441 tcgtcgaatt gcatccaggg gctggcggaa cggagtccca agactggggc agcatgcttt
    13501 tacgcatgta tacacgctgg gcagagcagc atgggtatca agtagagaca ctagattatc
    13561 aagcaggcga tgaagcagga atcaagagtg tgaccctact gatcaaagga cacaacgcat
    13621 ttggctatct gaaatcagaa aaaggtgttc atcgccttgt acgtatctcg ccttttgact
    13681 cagcaaaacg tcgtcatact tctttttgtt cggtagatgt gatgccagag cttgatgaaa
    13741 cgatcgatat agaaatcaat ccagatgatt tgaagatcga cacatatcgg gcgagtggtg
    13801 caggtggtca gcacatcaat aagacagaat ccgctgtacg aatcactcac ttgcctacag
    13861 gaacagtagt agcgagtcag gcacaacgtt cacaattgaa aaaccgggaa caagcgatgg
    13921 ggatgctgaa agctaagctt taccaattag aagtggaaaa gaaagaacaa gaagcagctg
    13981 cactgagagg agaacaaaaa gaaatcggct ggggatcaca gatccgttct tatgttttcc
    14041 atccatattc tatggtaaaa gaccatcgga caaacgtaga gacaggaaat gtccaagctg
    14101 ttatggacgg agatcttgat ttatttattg acggctattt gaaaatgcat ctgcaataag
    14161 agccctttgt taaattgaaa taaaattgta agattttgca agcaagttga aacattgcca
    14221 tgctataata gctaaagact gaaaaagata tggagagaac gccatgattg aaatgaagga
    14281 tgtaatgaag aagtactcaa acggtaccac tgctatccgc aatctctcga ttgtcatcga
    14341 acaaggagag tttgtgtatg ttgttggtcc gtctggagct ggtaaatcta cattcatcaa
    14401 attgatgtat cgagaagaaa aagcttcaaa aggaactttg aacgtcgcag gtcatgatct
    14461 aatagccatc aaaaaccgcg aagttcctta tctacgcaga gaaatcggcg tggtgttcca
    14521 agactataaa ttattaccaa gaaaaacagt atatgaaaat gttgcgtacg ccatgcaagt
    14581 tatcggcaga aaacctcggg atatcaaaaa acgagtaatg gaagtgctgg atcttgttgg
    14641 tttgaaacac aaagtccgag tctttcctag cgaattatct ggtggggaac aacaacgtgt
    14701 ttctattgcc cgagcaatcg taaatacacc taaagtactt atcgcggatg aaccgacagg
    14761 gaatctagat ccggaaaact catgggaaat catgaaacta ttagatcgga tcaatgcaca
    14821 aggaacaact gtcgtgatgg ctacacataa cagtacgatc gtaaatacga ttcgacaccg
    14881 agtaattgct atcgaaaacg gccgcattat tcgagaccaa gcggaagggg aatatggata
    14941 cgatgattag aacctttttc cgccatttat tagaaagtat caagagtttg aaacgtaacg
    15001 gctggatgac agtagcttcg gtcagtgcgg taacgatcac gttgacttta gttggtgtgt
    15061 tcatggcggt catcatgaac gcaaccaaac tagcacaaga tatagaagga aacgtggatg
    15121 tatctgtgtt cgtagacatt ggtacaaaag acgaagagat gaaaaaatta gaaaaagaat
    15181 taaatgactt agatcatgtc aaaaaagtcg aattttcaag caaagaacag gaattgaaga
    15241 aaatccaaaa cgaaatgggc gattcttgga aattgtttga aggggataat aacccgttat
    15301 atgatgtata cgtagtaagt gctaccgatc cttcttatac aaaacaagta gcagaaaaag
    15361 cggcagattt gaagaatgtt tcccgttctg attacggtgg ggcttcctca gatcggattt
    15421 tccaaattgc tggtgcagtt cgaacatggg gattagttgc ggcggcattg ctgctgtttg
    15481 tagcaatgtt tctcatttct aacacgattc ggatcacgat tttatctaga cagcgtgaaa
    15541 ttcaaatcat gcgtttagta ggggcaaaaa atggatatat ccgctggcca tttttccttg
    15601 aaggtggttg gatcggctta atcggtgcca ttcttccgat actgatcatt acatttggtt
    15661 acgcatggtt ttaccaattg atcaatccgt cattattacg atctcattat tcattgatcc
    15721 atccagaaaa tatcgtttgg aaaatcaatc ttttgatggt cggtattggt gtgatcattg
    15781 gttcactcgg ctcgatcatc tctatgagac gtttcttgaa attctagtgt cacaagataa
    15841 atataatcag aaagttggac gatttcgttc cagctttctt tttttatcag ctaggtggag
    15901 taaatggggc ggcttttttc tctttacttt aaaaaacaac ttgggtattc ttaagttggt
    15961 agaaaaagag gtgaagccgt gaagattatc gttgacaatt tttttacgat ccttttgatt
    16021 atgaatattt tgctttcctt tattatcgtt tttcgagaaa gaaaggaaac tgcgcaaaca
    16081 tgggcatggc tgctcgtttt gatgttcatt ccagttgtag gatttatttt atatattttt
    16141 ttaggaagag ggatttccaa agagaaaatc tttgatttga agatccaagg gaaaatcggt
    16201 aagaatctag aaatcgaaga agataaacaa gcattgatgc gagggcttta tcctcatccg
    16261 cctactggac aagtagatgt gaaacaattg atctatatgc ttactgtatt tgaaagtacg
    16321 ctttatacga ctaaaaatga aatcacttta tttacagatg gtcgtgaaaa attcgatgcg
    16381 ctgatcgagg atatcaaaca ggcagaagac catatccatt tccaatatta tatttaccgc
    16441 agtgatacat taggtgaaga agttcgagag gcattgacag aggcagcaag acgcggagta
    16501 aaagtcagag tccttcttga tgcatggggt tccacacaag tttcttctag tttttttcag
    16561 aatttgaaaa aagcaggtgg agaagtcgca tttttctttc ctctattcgt tccgtatatc
    16621 aatcctcgaa tcaattatcg caatcatcgt aaaatcgtag tgattgatgg gaaaatcgga
    16681 tatacaggtg ggttcaatgt tggaaacgaa tatctaggat tggtaaagaa atttggttat
    16741 tggcgagaca atcatctgcg tatctatgga gaagcggttt acaccttgca aaaccgtttt
    16801 ttgatggact ggaattctca gcatacaaaa gaagtaggat attcaccgga atttttcccg
    16861 accattcatt ctacaggtga tatggctgtt caaatcgtga caagcggacc agataccgaa
    16921 catgagcaaa tcaaaatgac atatttgaaa atgatttcgt tagccaaacg ggagatattg
    16981 atccaaacgc cgtattacat accggatgga tcgattcatg aggcattgaa gttggctctt
    17041 ctctcaggcg taaaagtcca tatccaaata cctaacaaac cagatcatct tctcgtttac
    17101 tgggcaacgt attctttcgc tgcagagctg atcgagtatg gggcaagaat cgaaacatat
    17161 gaaaatggat ttatccatgc aaagacgatg attatcgatg gcggcatcgt ttccgttggt
    17221 tcagctaata tcgacgttcg ctcatttaga ttggattttg aagtcaatac actgatctat
    17281 gatgaacgaa tggcttctcg cgtaagaaaa gcattctttg aagattcaaa gatttcgacg
    17341 catctcacaa aagaagtgta tgaaaaccga gggatgatga tcaagatgaa agaaggatta
    17401 gcaagactga tttcgccgct cctttaaaat acaaaaagga caggagagcc atcaatagat
    17461 ggaaatctcg cgtccttttt tctcggggcc atttctgaga gtacgtcaga aatggagaaa
    17521 gcgtctcgca tgagcgaaat taactttggg gtatctcttg ttttttgggg aaagcaagaa
    17581 ataagctaat atatgctatt aaaagagaca catttcaaag ccagtatagc atagaaactt
    17641 ttaatgagat agcttttttt gcaattatga gaatttattt tgttatttaa tgattttgat
    17701 tcgttttcat caagtaatga aaatgataga ataaacatac tttaggatta aaggagattt
    17761 ctaatgaaaa aactaaaatt attcttacca ataataggat tagctattct tttatcaggc
    17821 tgttcaaagt ggattgatcg aggagaatcc attactgcag ttggctcttc tgccttacag
    17881 cctttagtag aaacggttgc tgaaacctac caggcagaaa atcctggaaa attcatcaat
    17941 gtacaagggg gcggaagcgg aactgggttg tctcaagtac agtcaggagc agtcgatatc
    18001 ggaaattctg atttgttcgc ggaagaaaaa tcagggattg atgcttcggc attagtcgat
    18061 catcgagtag cagttgttgg aatcactcct attgtgaaca aggatattgg cgtaaaagat
    18121 atcagtatgg aaaacctgaa aaaattattt acgggcgaga tcaaaaactg gagtgaagtc
    18181 ggtgggaaag atcagccagt agttatattg aaccgtgcat caggaagcgg gacccgtagt
    18241 acgtttgaaa aatgggtatt ggacggagaa acagctgttc aggcacaaga acaagattca
    18301 agcggaatgg tgcgccaaat cgttgcggac acacccggag caatcagcta tgttgctttt
    18361 tcttacgttt ccgatgatgt ggatacgttg aacgttaacg gtgtggaacc aacagatgaa
    18421 aatgtgacaa cgaacaaatg gacgatttgg gcatatgagc atatgtacac aagagaccat
    18481 ccaaaaaaac tgacaaaaga atttttagac tatatcttat ctgatgaagt acaagataat
    18541 attgtcggag agctaggcta tatccctgtt tcacatatga aagttgaacg tgattggcaa
    18601 ggaaacattg ttaaagagta atctttacac aaaatttaca aacttagcta aacttttaca
    18661 tgttattaaa accaaattga tgttcaattt gtacactgag tgagtatgtt aaacctgatt
    18721 aagggggagt catctgtgga agatgtgaaa aaagtattat taacaaaatc aaaacgttca
    18781 aaaatggaac agcgcggaaa attcattagt tttttgtgta tcgcgctgat cgtgttggtt
    18841 gtattatcta ttttttattt tgtcgctagt aaaggattgg ccaccttttt tactgataag
    18901 atcaatgtat ttgattttct gtttggtaca gattggaatc caagccaaat aggagcaaat
    18961 gggaaaccca tggtaggggc attgcctatg atcacaggtt catttattgt gaccttttta
    19021 tctgctattg ttgccacacc atttgctatt ggagcagcag tgttcatgac ggagatttct
    19081 cctaaaaacg gaacgaagat cttgcaaccg gtcatcgagc tacttgtagg tattccgtct
    19141 gtcgtttacg gatttatcgg tttatctgtt atcgtgcctt ttgtcagaag tatctttggc
    19201 gggacagggt tcggtatctt agctggtaca tttgtgttat tcgttatgat cttaccgact
    19261 gtcacaacga tgactgtgga tgcattaaag gcagtgccgc gacactatcg ggaagcttca
    19321 ttagcgctag gtgccacaag atggcaaaca atctacaaag tggtgctgcg agcagcagtg
    19381 cccggaattt taacagcagt cgtttttggt atggctcgtg cgtttggcga agccttagct
    19441 atccaaatgg ttattggtaa tgcggcatta atgccaacag gacttactac tcctgcttct
    19501 acattgacgt ccatcttgac aatgggaatc ggaaatacaa tcatgggaac agttgaaaat
    19561 aatgtgttat ggtcattagc gctgatcttg ctattgatgt cattattctt taatatcgtg
    19621 atccgtatga ttgggaagaa aggagagctg aaataatgaa cgcaaaacgc tcagataaaa
    19681 ttgctacagg tgttctatat gtggtttcag ggatcatcgt attgatctta gcagctttat
    19741 tactttatat cttagttcga ggaataccgc acatttcatg gtcattcttg actgaacctt
    19801 ccaaagccta ccaagaaggc ggtgggatcg ggattcaatt atttaactcg atttatttgc
    19861 ttttgattac catgatcatc agttttccta tctctttagg tgcgggtatc tacctttcgg
    19921 aatatgccgg aaaaaactgg ctgacagacg tgatccgtac gtctatcgaa atcttgagct
    19981 ctttgccttc tgttgttgtc ggtttattcg gtttcttggt tttcgttatt caattccagt
    20041 atggtttctc aatcatttct ggtgcattag ctttgaccgt attcaacttg cctcttttga
    20101 ctcgaacggt cgaggaatct ttacaagcgg tccattacac acaacgagaa gctggattgg
    20161 cgttaggttt gtcacgctgg gaaacagtga taaaagtggt tgttccagaa gcgacaccag
    20221 gaattttgac tggtgtgatc ctaagttcag gaagaatttt tggtgaagct gccgcattga
    20281 tttatacagc tggtcaaagc gcgccagcat tagattttac gaactggaat ccattaagtg
    20341 tttctagtcc gatcagcatt ttccgccaag ctgaaacact ggctgtccat atttggaaaa
    20401 tcaacacaga aggtacgatg cctgatggtg tttctgtttc ggctggcgct tctgccgtgt
    20461 tgatcattgc tgttttactg ttcaacttcg gcgctcgtgc gattggcaaa cgattatacc
    20521 gaaaaatgac ttcagcctaa ggagaagaag taaaatgaaa aaatataatt ggaatgaaac
    20581 aaatgtcatt accatgccaa aagataagga agttgcatta tatacgaatg atctgcatgt
    20641 ttggtatggc gacaatgaag caatcaaggg agtggatcta gaattcgaaa aaaataagat
    20701 cactgcattg attggtccct ctggctgcgg aaaatccacg tatcttcgtt ctttgaatcg
    20761 tatgaatgat gggattgcta atacgaaaat tactggaaag attatgtata aagacgtgga
    20821 tatcaatgcg cctcaagtgg atgtttatga aatgcgtaaa cggatcggca tggtgttcca
    20881 acgccccaac ccttttagca aatcgattta tgacaatata acttttgctt tgaaacagca
    20941 tggtgaaaaa aacaaaaaga aattagatga aatcgttgaa acaagcttga aacaagcagc
    21001 tttgtgggat caagtaaaag atagcttgga taaaagtgcc ttggctttat ctggcggaca
    21061 acagcaacgt ttgtgtatcg ctcgtgcaat cgcgatgaaa cccgatatct tgctgttaga
    21121 cgagccggca agtgccttgg atcctatttc gacaggaacg gttgaagaaa cacttgtaaa
    21181 cttgaaagaa gactacacga tcattatcgt gacgcataat atgcaacaag cagctcgtat
    21241 cagcgactat actgcctttt tctatctagg aaaagtaatg gaatatgaca aaacaaacaa
    21301 gatatttacc agaccaaaaa ttcaggcaac cgaagattat gtgtccggtc attttggtta
    21361 agacggaggc ctcaacatga caaaagaaat tatctcatcc aaagatcttc atctgtatta
    21421 tggaaagaaa gaagcactaa agggaattga tctaagtttc aatcaaggtg aaatcacagc
    21481 gatgatcggt ccttctggtt gcgggaaatc tacctatcta cgttcgttga atcgaatgaa
    21541 cgatctgatt ccaaatgtaa cgatcaccgg aagtgtttta tataaagaca aagacatcta
    21601 tggtccgaaa acagatgttg ttgaactaag aaaagaaatc ggcatggtgt tccaacagcc
    21661 aaatccattt cctttttcta tttatgaaaa tgtcatctat ggattgaagt taaaaggtga
    21721 aaaagataaa aaagtccttg atcaagtagt ggaagaaagt ctgaaggcag cgtccgtttg
    21781 ggaggatgtg aaagataaac tgcataaaag tgccttgtct ttatccggtg ggcagcagca
    21841 gcgtgtatgt atcgcacgtg ttttggcagt gaatcccgaa atcatcttat tggacgaacc
    21901 aacaagtgca cttgaccctg tttctactgg gaaaatcgaa agtatgctgt tagaattaag
    21961 agagcggtat acgatgatca tcgtgaccca taatatgtct caagcttcac gtatttcaga
    22021 taagacggca ttctttttag atggtcactt gatcgaatac aacgatacga agaagatatt
    22081 catgaatcca gaaaaacaag agacagaaga ttatatttca ggtcgatttg gataaggagg
    22141 aaacggaatg ctacgtacac aatttgaaga agaattgctg aatctccata atcagttcta
    22201 cgaaatgggg atgatggtga gcagcgctgt gcacaagtca gttcgtgcat acatcaaaca
    22261 cgataaaatc ttagctcaag aagttatcga aaacgatata aatatcaata atatggaaac
    22321 gcgtttggag aagaaaagtt ttgaaatgat tgcattacaa cagccagtta caactgactt
    22381 gcgtatgatt atcacggtca tgaaagctag ctctgattta gaacgtatgg ccgatcatgc
    22441 ggtgtccgtt gctaaatcca caatccgcgt aaaaggacag acgagaatac cggaaatcga
    22501 aaaagagatc tccgatatgt ccgattacgt gaaaaaaatg gtggacaacg tcctagttgc
    22561 gtatgtcaaa acagacgaaa aagatgcgcg tacaatcgcc aatatggatc aaagagtcaa
    22621 tgactatttc aatcgaatct ataatgcaac catcaaaaac atgcaagaaa atcctgaaac
    22681 agtcatcagt ggcacagact atttgaatgt tgccagctat ctagaacgaa tcggagacta
    22741 tgtgacaaac atctgtgaat ggatcgtcta cttggctaca gggaaaatca ctgaattaaa
    22801 tacgaaccac aatgagattt tctaaactga agttgtgatt ctgctgttta tttaggaaaa
    22861 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaacggta aaatagttcc
    22921 tcatattttg ccgttttttg agctaatacc gaaggtcagc tgattgaaca ccgtttattc
    22981 tggaaaaggg tttgtgacaa aacatgtcac aaaccctttt cattattcca atagaaagga
    23041 taaagaatgc aaaaaaagat tagcatcatc atcactctat tttttatttg tatacttgct
    23101 tcatggttta ttcagcgtca agctgctcta tatgacgtac ctgtcatcga gatcgaaaga
    23161 gtgagaatag aagaggatca acaattgatt acaggaagat tgatgaatac ggaccaaaaa
    23221 ggagaagtga tttctttaac ggctccttat caaaaaaatc aaatcgaaac agcaaatata
    23281 acaacaagac aaatctatct tgtccaaatg catggagatg aatggcaact agtagcaaaa
    23341 aaaaatgatg gctggctttt tttctttaca agtgtcttca ttggcaccat gttgcttatt
    23401 ggtggaaaac agggcgtatt tgctttagga agtctcatca tcaacatcgt tttactttta
    23461 cttttgttgc tcctctttac caaaacagaa ggtatttctc tcttaaatat agcaatctta
    23521 tttgtcgtta tagggataat cgttagtata ttggcgttag acggatggaa tagaagcagt
    23581 ataatcaaaa tttcggctgc agttacaagt gtttttttag cattttttat ttgtcttttg
    23641 acaatgaatc attggaaaga tcaaggactg cgctatgaag aactgaatta tctgacacga
    23701 ccgtatcgtt ctgtttttct ttccagcgtg ctgattggga cagctggagg gacactcgat
    23761 accgtgatca cagtcattgc gacattagaa gaattgacca agcaacaacc gaaaatatca
    23821 gcgaaacagt tatggctttc aggaaggcaa gtgggccgag atgtgattgg ttcgatggct
    23881 aatatccttt tattcgtcta tatcagcgga gcgattccat cgcttctgtt atatttagga
    23941 aatcaatggt ctttcaaaga aacggtagaa cgacatttat cattagaact tttacgcgtc
    24001 attgctggca gcttaggaat agtattatca atccccatcg cggtcctctt ttttctcgct
    24061 gtaaggaggt taaaaaaatg aatgtactta ttatacttgt tgggattttt gcaatcagtg
    24121 tgctatttgt cggtggtacg caaggtatgt atattctttt aggattattc attaatttag
    24181 gaatcttttt cctattatta ttcggctatc atcagaagtg gccgatattg gtattgtcga
    24241 ttatagggtt cctattgatc gctgtggtta tcttattttt tatcaatggt tataatctga
    24301 aaatgcgagc cgcttttgcc agtatactga tctttttgtt ttgtttccta ctattgattc
    24361 ctatcactga ttttttagcg atccaaggct ttacttcgat agaactagaa gaactatctg
    24421 gcttagataa gacgttagca attgatttta gactacttac gaggtcgttg cttctgatca
    24481 gtcttagcgg agctgtttta gatgcgagtg tagcgatttc tagtggaaca ttcgaagtat
    24541 atcaggcaaa tccgcaaatg tcttttaacc aattgcgcca tgctagcttt gccattgcta
    24601 aaaaaatatt ggcatcaaca gtgatgacgc ttctttttgc gtttatgggg agttctttag
    24661 cgttgattct ttggtttatt gacttagaca tttcttttca gcaaataatc aatgaaaaat
    24721 catttgtctt ggaatatacg atggctattc ttaccacact ggccgcacta cttgtcctgc
    24781 ccttaacttg cgtgactaca gcatatctct ttacaaaaaa gaaagaacat ctcaagatgg
    24841 agtaaaagtt acaacttaag tcctatgaca tttttactga atcagtgcat aatatggatg
    24901 taaggaaaag cttgcaaaca attttgctta aggaggcaat ttccatgaaa gaaagagaac
    24961 gtattttaga cttagtgaaa aaaggaatcc tttcgactga agaaggctta gatttattag
    25021 aaagcatggc aactgaaaaa gacgaaaaac aaatcaaaaa agaagcagac aaggtaactg
    25081 ctagtcataa agaaaaagat caggcaagtc aattgatcga tgaacttgaa aacggtgaag
    25141 aaaaaatttc tgagccagtt gatccaaaag aaaaagaaag acaagatcaa gaaaacttag
    25201 aaaagatctt agatgaacta gcaactgaag cgaataaaac ttcggcgcgt ctagacgaag
    25261 taaatgctca attcgctgac aataaggcag cacgtaatga gaaacaggaa gcattgatgc
    25321 agctgaatac aaaagaagaa ttaggcgagt tgacagaaga agaattagca cagcgtcaaa
    25381 cgttagaagc agaaatcaaa gagttagaag caaccggcga tacactatta gaagaacaat
    25441 tgaagctgga agcagaatta aaagatatcc gcaagaatca atggtctgag aaaaaagaaa
    25501 catttacgga taagtttgaa ttgccagatg attggaaaga tcaagcgaca gatacgctga
    25561 atcaagtagg cgaaaaaatg tcagaagctg gatcacagtt aggcaaattc ttgaagaaaa
    25621 cattccaaac tgtttcagaa acagtaaatg ataacatgga atggaaagat gtcagcttac
    25681 gcgtccctgg aattgcgaca acgaaatttg aacacgaatt ttattatgaa gctcctgcag
    25741 caagtatcct tgatatcaag gcagcaaacg gaaacgtgac gttaaaaacg tgggacagtg
    25801 atgatgtgaa agtggaagcc aagatcaaac tttacggaaa aatgggtgct gaaccatttg
    25861 aagcattctc tgaacggagc cagatcgagg tcaatgaaga tcatatctcc ttccaaattc
    25921 caaataagcg tgtgcgtgca gaccttgttt tctacttgcc taaacgagta tacgaccatg
    25981 cagctatcaa acttctaaat ggcaacatca tgattgagac attggaagct aaagatattt
    26041 atacaaaatc tacgaatggg aacatcatcg tgaaccaatt aactgcaacg atgctggaag
    26101 tagaaggtgt aaacggcaat atcgatattc gaaacgggaa catcttagat tctattatag
    26161 aaacagtaaa cggtacagtg acatttggtg ccacaccaga aaacctttct gtgtctttag
    26221 taaatggtga tgtacgtctt acgattaaag aagataattt gaaaaaagta gaagcaagtt
    26281 cagtgaacgg gaatgtcaaa gttgctttac cagatagcat cggtttggaa ggacacgcta
    26341 aaacaagtct tggaagcatt aacagccgtc tgtccaatta cgaagtagtt cgtgagaaaa
    26401 aagaacggac aaaccaaatg ttgcaattcc gtcgtgtttc agatgatgag atcgcacaag
    26461 tgcagctttc aacgacaaca ggaagtatct atttaaaaga tacagataaa taaagaggtt
    26521 gtgaaagaga tgttcagcct tgagcaataa gaagcgattt tttaaaatag cttcccctat
    26581 tttaaaaaaa tgtgccttat tgccgatagg ctatctcttg aacaccgatt aagaagaagg
    26641 ttgtcacaac gattttcttc atttaaaata gtagaacaga ggtgagacat gatgaaaaaa
    26701 aagttgacaa aatccaataa aaatgttgtt ttgacaggta ctttagcagg gattggggaa
    26761 tatatcggga ttgatcccac tgttatccgt gtgctttatg tattcttaag cttagttgct
    26821 tttggaagtc caatcatttt atacatttta ttagctttga ttatcccatc tgcgcgttct
    26881 gcacgaacaa actatggaca taacaatgca tattatgaaa aaaacaatta tcgtgaacaa
    26941 acaaaaaaac gcaaagaagc ggaaaaaatc gatgatgacg aatggagtga cttttaatgt
    27001 cgtactttca gcgtattttg gttaatacgt taacattcat atcgttggct gttctttttc
    27061 ctgcgatggt ccatgtgagc agtatttgga cggccgtcct tgccagcttc gtattatctg
    27121 tgttgaacat gtttgtcaaa ccgattttga cgatcctgtc cctgcccttt acattagtca
    27181 cattgggatt gtttacgttt gttatcaatg cagcgattct taaaatgact tccttttttg
    27241 taggagcaga acattttagt ttttcttcat ttggtgcagc gttattcgta gctatcttga
    27301 tgtcacttgt caatgtaatt gttagtgaac ataacagcag aaaataaaaa aagctgtgcc
    27361 gagatctcgg cgcagctttt
//
LOCUS       DAIGQM010000040        26873 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.040, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000040 DAIGQM010000000
VERSION     DAIGQM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.040"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..411
                     /locus_tag="NOA48_001673"
     CDS             <1..411
                     /locus_tag="NOA48_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0789932.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            509..697
                     /locus_tag="NOA48_001674"
     CDS             509..697
                     /locus_tag="NOA48_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0789933.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(755..1108)
                     /locus_tag="NOA48_001675"
     CDS             complement(755..1108)
                     /locus_tag="NOA48_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789934.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1639..2061
                     /locus_tag="NOA48_001676"
     CDS             1639..2061
                     /locus_tag="NOA48_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0789935.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2058..2288
                     /locus_tag="NOA48_001677"
     CDS             2058..2288
                     /locus_tag="NOA48_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0789936.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2786..2986
                     /locus_tag="NOA48_001678"
     CDS             2786..2986
                     /locus_tag="NOA48_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0789937.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3013..4206
                     /locus_tag="NOA48_001679"
     CDS             3013..4206
                     /locus_tag="NOA48_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0789938.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOA48_001680"
     CDS             complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOA48_001680"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0789939.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5898..6821)
                     /locus_tag="NOA48_001681"
     CDS             complement(5898..6821)
                     /locus_tag="NOA48_001681"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0789940.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7017..7622
                     /locus_tag="NOA48_001682"
     CDS             7017..7622
                     /locus_tag="NOA48_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0789941.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7930..8946
                     /locus_tag="NOA48_001683"
     CDS             7930..8946
                     /locus_tag="NOA48_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0789942.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9087..10388
                     /locus_tag="NOA48_001684"
     CDS             9087..10388
                     /locus_tag="NOA48_001684"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0789943.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            10434..11096
                     /gene="deoC"
                     /locus_tag="NOA48_001685"
     CDS             10434..11096
                     /gene="deoC"
                     /locus_tag="NOA48_001685"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0789944.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11117..11515
                     /locus_tag="NOA48_001686"
     CDS             11117..11515
                     /locus_tag="NOA48_001686"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0789945.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11581..12663
                     /locus_tag="NOA48_001687"
     CDS             11581..12663
                     /locus_tag="NOA48_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0789946.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12875..14437
                     /locus_tag="NOA48_001688"
     CDS             12875..14437
                     /locus_tag="NOA48_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789947.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            14430..15563
                     /locus_tag="NOA48_001689"
     CDS             14430..15563
                     /locus_tag="NOA48_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789948.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15563..16519
                     /locus_tag="NOA48_001690"
     CDS             15563..16519
                     /locus_tag="NOA48_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0789949.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16618..17784
                     /gene="deoB"
                     /locus_tag="NOA48_001691"
     CDS             16618..17784
                     /gene="deoB"
                     /locus_tag="NOA48_001691"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI0789950.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17808..18626
                     /locus_tag="NOA48_001692"
     CDS             17808..18626
                     /locus_tag="NOA48_001692"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0789951.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18643..19350
                     /gene="deoD"
                     /locus_tag="NOA48_001693"
     CDS             18643..19350
                     /gene="deoD"
                     /locus_tag="NOA48_001693"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0789952.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOA48_001694"
     CDS             complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOA48_001694"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0789953.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20506..21087)
                     /locus_tag="NOA48_001695"
     CDS             complement(20506..21087)
                     /locus_tag="NOA48_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0789954.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOA48_001696"
     CDS             complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOA48_001696"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCI0789955.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            22222..22635
                     /gene="rpsL"
                     /locus_tag="NOA48_001697"
     CDS             22222..22635
                     /gene="rpsL"
                     /locus_tag="NOA48_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCI0789956.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22719..23189
                     /gene="rpsG"
                     /locus_tag="NOA48_001698"
     CDS             22719..23189
                     /gene="rpsG"
                     /locus_tag="NOA48_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCI0789957.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            23283..25370
                     /gene="fusA"
                     /locus_tag="NOA48_001699"
     CDS             23283..25370
                     /gene="fusA"
                     /locus_tag="NOA48_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0789958.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25542..26729
                     /gene="tuf"
                     /locus_tag="NOA48_001700"
     CDS             25542..26729
                     /gene="tuf"
                     /locus_tag="NOA48_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0789959.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
BASE COUNT         8464 a         4955 c         5695 g         7759 t
ORIGIN      
        1 ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac tcctattgta
       61 ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa atattgtgca
      181 aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga aattcctgct
      241 cgatgtattc aagattatcg caatgattta acttttttta caaatgggct tagtgtttgt
      301 ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca gacccgtcgt
      361 ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta gtgcgtttta
      421 tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta atatagattt
      481 gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat tgtgtcctat
      541 ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa atttcccttt
      601 atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga atataataac
      661 aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa actctcatct
      721 tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt cttgcttcat
      781 tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag ctatccatgt
      841 atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt
      901 catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta cttgggtgtt
      961 gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt gttcccactt
     1021 gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca acggctctaa
     1081 aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt tactgttcct
     1141 atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc ctatagaaca
     1201 ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct gattttattt
     1261 acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa ttggcgactt
     1321 aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct taattaagtt
     1381 cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg tggttttgca
     1441 gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt ttatgtgctt
     1501 ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac aaatcccccg
     1561 ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc ctttcacgac
     1621 agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga aaatcagttt
     1681 gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa acatctagac
     1741 agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt caactctttt
     1801 tctactgttg atacgtacgt cactgatttc caactattta aattatttgg attaagaatc
     1861 aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac
     1921 attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga gttactaaat
     1981 ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat taaagaattc
     2041 atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc ctcattgtaa
     2101 aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat cgagggtata
     2161 cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat atggttattg
     2221 atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta tcgttcgaaa
     2281 ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg
     2341 gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata ggctaacaag
     2401 ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa gaaaagagct
     2461 gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag taattcgaaa
     2521 gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata ctcccgtata
     2581 gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg agaaccatgc
     2641 agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata ttcttctctt
     2701 gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg agttttccta
     2761 gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt tagttgagct
     2821 aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat tgatgattac
     2881 aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg aagctgttga
     2941 agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt tgcacagtaa
     3001 ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac ctattatttt
     3061 cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc
     3121 actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa accagaagaa
     3181 ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat tttccttcca
     3241 tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac tattaagaag
     3301 catttctctt attttgataa aatggctgtt tccgatattg agcctattga tgtgcaaaat
     3361 tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt tcaaggacta
     3421 ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa tccatctaag
     3481 attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa agaagaattt
     3541 gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt atttatctct
     3601 ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat tcaatgggaa
     3661 gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta caagaatcaa
     3721 tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat tgtattagat
     3781 aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct aattcagaca
     3841 gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc atatgctatt
     3901 gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt acggcattct
     3961 catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga tcgtctagga
     4021 cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa cagtaatttc
     4081 gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca aaattatgat
     4141 acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg
     4201 caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa gaggatttct
     4261 agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
     4321 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
     4381 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
     4441 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
     4501 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
     4561 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
     4621 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
     4681 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
     4741 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
     4801 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
     4861 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
     4921 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
     4981 ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
     5041 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
     5101 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
     5161 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
     5221 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
     5281 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
     5341 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
     5401 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
     5461 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
     5521 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
     5581 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
     5641 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
     5701 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
     5761 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
     5821 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
     5881 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
     5941 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
     6001 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
     6061 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
     6121 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
     6181 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
     6241 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
     6301 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
     6361 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
     6421 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
     6481 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
     6541 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
     6601 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
     6661 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
     6721 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
     6781 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
     6841 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
     6901 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
     6961 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
     7021 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
     7081 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
     7141 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
     7201 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
     7261 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
     7321 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
     7381 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
     7441 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
     7501 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
     7561 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
     7621 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
     7681 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
     7741 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
     7801 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
     7861 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
     7921 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
     7981 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
     8041 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
     8101 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
     8161 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
     8221 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
     8281 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
     8341 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
     8401 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
     8461 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
     8521 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
     8581 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
     8641 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
     8701 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
     8761 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
     8821 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
     8881 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
     8941 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
     9001 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
     9061 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
     9121 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
     9181 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
     9241 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
     9301 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
     9361 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
     9421 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
     9481 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
     9541 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
     9601 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
     9661 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
     9721 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
     9781 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
     9841 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
     9901 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
     9961 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    10021 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    10081 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    10141 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    10201 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    10261 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    10321 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    10381 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    10441 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    10501 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    10561 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    10621 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    10681 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    10741 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    10801 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    10861 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    10921 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    10981 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    11041 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    11101 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    11161 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    11221 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    11281 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    11341 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    11401 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    11461 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    11521 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    11581 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    11641 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    11701 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    11761 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    11821 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    11881 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    11941 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    12001 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    12061 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    12121 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    12181 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    12241 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    12301 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    12361 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    12421 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    12481 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    12541 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    12601 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    12661 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    12721 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    12781 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    12841 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    12901 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    12961 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    13021 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    13081 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    13141 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    13201 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    13261 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    13321 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    13381 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    13441 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    13501 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    13561 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    13621 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    13681 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    13741 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    13801 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    13861 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    13921 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    13981 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    14041 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    14101 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    14161 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    14221 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    14281 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    14341 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    14401 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    14461 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    14521 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    14581 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    14641 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    14701 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    14761 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    14821 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    14881 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    14941 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    15001 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    15061 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    15121 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    15181 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    15241 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    15301 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    15361 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    15421 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    15481 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    15541 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    15601 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    15661 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    15721 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    15781 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    15841 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    15901 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    15961 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    16021 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    16081 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    16141 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    16201 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    16261 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    16321 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    16381 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    16441 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    16501 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    16561 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    16621 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    16681 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    16741 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    16801 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    16861 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    16921 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    16981 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    17041 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    17101 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    17161 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    17221 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    17281 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    17341 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    17401 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    17461 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    17521 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    17581 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    17641 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    17701 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    17761 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    17821 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    17881 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    17941 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    18001 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    18061 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    18121 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    18181 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    18241 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    18301 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    18361 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    18421 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    18481 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    18541 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    18601 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    18661 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    18721 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    18781 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    18841 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    18901 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    18961 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    19021 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    19081 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    19141 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    19201 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    19261 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    19321 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    19381 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    19441 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    19501 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    19561 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    19621 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    19681 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    19741 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    19801 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    19861 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    19921 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    19981 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    20041 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    20101 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    20161 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    20221 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    20281 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    20341 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    20401 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    20461 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    20521 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    20581 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    20641 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    20701 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    20761 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    20821 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    20881 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    20941 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    21001 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    21061 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    21121 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    21181 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    21241 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    21301 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    21361 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    21421 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    21481 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    21541 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    21601 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    21661 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    21721 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    21781 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    21841 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    21901 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    21961 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    22021 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    22081 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    22141 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    22201 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    22261 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    22321 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    22381 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    22441 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    22501 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    22561 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    22621 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    22681 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    22741 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    22801 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    22861 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    22921 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    22981 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    23041 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    23101 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    23161 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    23221 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    23281 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    23341 atgctggtaa aacgactgct actgaacgta tcttatacta tactggtaaa atccataaaa
    23401 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    23461 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    23521 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    23581 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    23641 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    23701 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    23761 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    23821 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    23881 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    23941 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    24001 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    24061 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    24121 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    24181 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    24241 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    24301 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    24361 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    24421 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    24481 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    24541 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    24601 caaatgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    24661 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    24721 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    24781 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    24841 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    24901 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    24961 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    25021 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    25081 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    25141 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    25201 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    25261 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    25321 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttaaaa
    25381 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    25441 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    25501 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    25561 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    25621 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    25681 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    25741 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    25801 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    25861 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    25921 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    25981 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    26041 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    26101 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    26161 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    26221 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    26281 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    26341 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    26401 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    26461 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    26521 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    26581 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    26641 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    26701 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    26761 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    26821 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaa
//
LOCUS       DAIGQM010000041        26598 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.041, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000041 DAIGQM010000000
VERSION     DAIGQM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.041"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            99..542
                     /locus_tag="NOA48_001701"
     CDS             99..542
                     /locus_tag="NOA48_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0789960.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="NOA48_001702"
     CDS             complement(548..1732)
                     /locus_tag="NOA48_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCI0789961.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="NOA48_001703"
     CDS             2000..2698
                     /locus_tag="NOA48_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0789962.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="NOA48_001704"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="NOA48_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCI0789963.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="NOA48_001705"
     CDS             complement(3508..4041)
                     /locus_tag="NOA48_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789964.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="NOA48_001706"
     CDS             complement(4338..6719)
                     /locus_tag="NOA48_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0789965.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOA48_001707"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOA48_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCI0789966.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="NOA48_001708"
     CDS             7420..7959
                     /locus_tag="NOA48_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCI0789967.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="NOA48_001709"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="NOA48_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCI0789968.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="NOA48_001710"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="NOA48_001710"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="NOA48_001711"
     CDS             9066..10232
                     /locus_tag="NOA48_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCI0789969.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="NOA48_001712"
     CDS             10278..11774
                     /locus_tag="NOA48_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCI0789970.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="NOA48_001713"
     CDS             11855..12538
                     /locus_tag="NOA48_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0789971.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13183..14373
                     /locus_tag="NOA48_001714"
     CDS             13183..14373
                     /locus_tag="NOA48_001714"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCI0789972.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14475..15428
                     /locus_tag="NOA48_001715"
     CDS             14475..15428
                     /locus_tag="NOA48_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCI0789973.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15497..16846
                     /locus_tag="NOA48_001716"
     CDS             15497..16846
                     /locus_tag="NOA48_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0789974.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17029..17352)
                     /locus_tag="NOA48_001717"
     CDS             complement(17029..17352)
                     /locus_tag="NOA48_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789975.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17481..18644
                     /locus_tag="NOA48_001718"
     CDS             17481..18644
                     /locus_tag="NOA48_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0789976.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18714..20063
                     /locus_tag="NOA48_001719"
     CDS             18714..20063
                     /locus_tag="NOA48_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0789977.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20108..20539)
                     /locus_tag="NOA48_001720"
     CDS             complement(20108..20539)
                     /locus_tag="NOA48_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0789978.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20927..23569
                     /gene="alaS"
                     /locus_tag="NOA48_001721"
     CDS             20927..23569
                     /gene="alaS"
                     /locus_tag="NOA48_001721"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCI0789979.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23769..24365
                     /locus_tag="NOA48_001722"
     CDS             23769..24365
                     /locus_tag="NOA48_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0789980.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24487..25635
                     /locus_tag="NOA48_001723"
     CDS             24487..25635
                     /locus_tag="NOA48_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0789981.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25673..26086)
                     /locus_tag="NOA48_001724"
     CDS             complement(25673..26086)
                     /locus_tag="NOA48_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCI0789982.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26165..26596
                     /locus_tag="NOA48_001725"
     CDS             26165..26596
                     /locus_tag="NOA48_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCI0789983.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
BASE COUNT         8810 a         4607 c         5524 g         7657 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagttgc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggggt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg tcacagtcct
    12781 tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa ttaaaaattg
    12841 ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata aataaattaa
    12901 atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt gttgtattta
    12961 tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat actatataag
    13021 tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt ctcataatca
    13081 gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca cgatatatgt
    13141 ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc caaagaacta
    13201 acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata caatacgatc
    13261 gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa gatgatcaat
    13321 ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa agcatgtatt
    13381 gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa tggttcgctg
    13441 aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga agcagcaatc
    13501 gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat gacaaaagaa
    13561 gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg ccgcttatcc
    13621 ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa aaaagcaaag
    13681 gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg tgttttctcc
    13741 atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa atatggactg
    13801 atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc aggaaccgtc
    13861 aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc gaaagctata
    13921 ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt gaaagctaga
    13981 agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc tgcattggct
    14041 tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga aaatgctaat
    14101 tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga aacacctatt
    14161 actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa gctgatcgaa
    14221 catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac aggcaggatc
    14281 agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt agcagtttat
    14341 caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc gtctatttaa
    14401 aattagagaa catgttcacg catatattgt taatcatctg aagatagtag taaaaaagat
    14461 cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa attggttcag
    14521 agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg acagatatac
    14581 gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta atggattacg
    14641 aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat ttggctgctc
    14701 ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac gtgactgggc
    14761 tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg ccaagttcaa
    14821 tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact cttcagcgtc
    14881 ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat tattattatg
    14941 tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct tatgcaacct
    15001 tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca atcaaagaag
    15061 gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat atgccagatg
    15121 cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt catcgaaatg
    15181 ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct attcaaaaaa
    15241 tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca atagcagaat
    15301 cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt tcgccgaaat
    15361 acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa ttggtagaga
    15421 cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt ggctatggta
    15481 tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag taaaaataga
    15541 aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta tgggcacagt
    15601 gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag gatccgccag
    15661 tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag gactaacagg
    15721 agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata tcgaacggat
    15781 ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt attttccagc
    15841 aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat ttggtctttc
    15901 ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt tgatcaattt
    15961 tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca agcttattcc
    16021 tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact tccaactgtt
    16081 tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg gcttgctagc
    16141 aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag aattgaaaaa
    16201 gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca tgatcgttta
    16261 tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg caggaaacag
    16321 caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa gactggtcac
    16381 agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta ctggaatgcg
    16441 tctcccttat gttattgcaa aagaaaacaa cctgcctttt agcaagctct ttgctaaact
    16501 tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca tcgctattgg
    16561 catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg tcatttggat
    16621 tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac ctgatttgtt
    16681 tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca ttggagggac
    16741 ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg ggatagtatt
    16801 gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa aacattcgaa
    16861 ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga ggagtacgtg
    16921 gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt gtctacgatg
    16981 aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt actttgattt
    17041 gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca agcaaccaga
    17101 aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag acaaagcatg
    17161 tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat tgaagactag
    17221 catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag ttctttttct
    17281 tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa aaacaaagta
    17341 catattcagc atctcgacac cccctttgtg tttatcttac tttactttga aagaaatgag
    17401 aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa gagagataca
    17461 aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt gcgctgattg
    17521 tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa tatcgaaagt
    17581 atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt tatttattgt
    17641 gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc caaatgacag
    17701 ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac aacacggtat
    17761 tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta tttttggaac
    17821 cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat tatttccggc
    17881 tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt gaattgacgc
    17941 agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat gtgaatgatt
    18001 tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta tttacattta
    18061 tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag actgtctcat
    18121 tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt attaatttgg
    18181 tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct catatctggt
    18241 ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc aatggatgga
    18301 cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa cgaatttctt
    18361 taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt ttaagctggt
    18421 tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg cagatgagtg
    18481 cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta aatatcttgc
    18541 tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac acatatactg
    18601 ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc aaaaacgctt
    18661 tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca cgaatgaata
    18721 attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca aagggcttca
    18781 aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga aaaaatatca
    18841 ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct ttgtttgaaa
    18901 aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt agggaactag
    18961 ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg gagatccgtg
    19021 tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg catcaccaac
    19081 agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat gaacaagcgc
    19141 tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca ttggatatgg
    19201 gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg cagtttttag
    19261 ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac atggaaaatc
    19321 caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa aattggctga
    19381 tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca attggtcatc
    19441 cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt gccgattact
    19501 tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca agagagagaa
    19561 aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg actgatttag
    19621 ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa attccagaag
    19681 atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta aaaggaacgg
    19741 ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa aaattgggcg
    19801 tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac gatcgtaata
    19861 gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt ggtcttgtga
    19921 agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg gcaattgcag
    19981 aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact gctcgtaaaa
    20041 ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt gtcacaatct
    20101 cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct tcaataaaag
    20161 gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc atttcagcta
    20221 ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct tcaagcaact
    20281 gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc ggcttgaagc
    20341 aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga tcaagaaata
    20401 gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca ggaatccctt
    20461 gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc cattcatccg
    20521 ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat gtattgattc
    20581 ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga aaataaaaat
    20641 tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa aggatatgat
    20701 ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag tcactaatca
    20761 aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt atcgagttta
    20821 agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc gtccttggct
    20881 gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga aacaattaag
    20941 tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac atacgattga
    21001 acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca actctggtgt
    21061 tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa gaatcacaaa
    21121 tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag cacggcacca
    21181 tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa atgaagccat
    21241 ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc cagaaaaact
    21301 ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg aagaagttgg
    21361 cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg gtgcaggccc
    21421 atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg atttagcaga
    21481 agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa tctggaactt
    21541 agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc ctcataaaaa
    21601 cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg cgtcaacgaa
    21661 ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa gcaaacaagt
    21721 aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag atcatattcg
    21781 cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga gagggtatgt
    21841 cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta ttgaacaagc
    21901 attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt atcctgaagt
    21961 acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac gtttcaatga
    22021 aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa aaaacgaaaa
    22081 cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg gcttcccggt
    22141 agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg ctggttttga
    22201 aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg aaaaatcaat
    22261 gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca ttggatacac
    22321 agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc ttttgaatga
    22381 agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg cagaaatggg
    22441 tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg tagcagttgt
    22501 tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag taaaagcacc
    22561 aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca atcggatcat
    22621 caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac ttggcgagca
    22681 tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact ttacccactt
    22741 tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg aaaaaatctg
    22801 ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa acatgggtgc
    22861 aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata ttggcggctg
    22921 gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg gaatcttcaa
    22981 aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg taacaagtaa
    23041 agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag caacaattgt
    23101 taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac agcaagtaag
    23161 agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac aagctggtga
    23221 tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac aagtaaaagt
    23281 gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa atatttcaga
    23341 tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg caatgacgaa
    23401 agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg caccgaaagt
    23461 aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa atcctgctgg
    23521 tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg gcgtttacgt
    23581 ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg cgaagacaaa
    23641 caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat ggtcggattc
    23701 ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa ataaaaaggg
    23761 gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg atcttgttag
    23821 caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta ggattcatta
    23881 gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc ccaaaagatg
    23941 gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat gccatgccaa
    24001 caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt cccagagtac
    24061 ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat aaatcaataa
    24121 cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc ttagtgttag
    24181 gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta gactctgctc
    24241 ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa gcaataggtg
    24301 cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg ttgaaaccag
    24361 aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag gaagagagga
    24421 gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact agaaggggta
    24481 aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca gcggacaaaa
    24541 aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt tgtctctaag
    24601 ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt gaacagtcta
    24661 tcagatactg cttcatccat attgactttg atcggattta aaattgctgc aaagccagca
    24721 gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt atttgtttcg
    24781 atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa aatcatccat
    24841 ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc catctttttg
    24901 aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc tgaaacattg
    24961 agagctacag caacagatag ttataatgat gtctttacta cactggctgt attgctttca
    25021 gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt tgctttagca
    25081 ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga actattagga
    25141 agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc ttgcgatgat
    25201 atacttggct atcatgattt attggtgcat aactatggac ccaataaacg ctttgcatca
    25261 gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat tattgatctg
    25321 atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt ggatccaatg
    25381 cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat tcttcttgaa
    25441 acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa aacgctgcaa
    25501 tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga aagaatctta
    25561 cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt tgatcacaat
    25621 tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta atttaaagag
    25681 tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct gctcctttat
    25741 ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga agttcttgga
    25801 ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg accgtagaaa
    25861 ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg tttttcttta
    25921 gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc cctatagaaa
    25981 gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca cctccactag
    26041 gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa agagattctc
    26101 ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg tgagaggtta
    26161 gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca tctattggtc
    26221 attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca caggtcctta
    26281 ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag gtttgcggcg
    26341 ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt ggaaagaccg
    26401 agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg tgcaaatgat
    26461 gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc aagtagtcct
    26521 ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc cttatacgaa
    26581 aaaaagaaaa agctaatt
//
LOCUS       DAIGQM010000042        26024 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.042, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000042 DAIGQM010000000
VERSION     DAIGQM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.042"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            108..1010
                     /locus_tag="NOA48_001726"
     CDS             108..1010
                     /locus_tag="NOA48_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0789984.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(1051..2937)
                     /locus_tag="NOA48_001727"
     CDS             complement(1051..2937)
                     /locus_tag="NOA48_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0789985.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(3034..3885)
                     /locus_tag="NOA48_001728"
     CDS             complement(3034..3885)
                     /locus_tag="NOA48_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0789986.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(4208..5992)
                     /locus_tag="NOA48_001729"
     CDS             complement(4208..5992)
                     /locus_tag="NOA48_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0789987.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(5992..7743)
                     /locus_tag="NOA48_001730"
     CDS             complement(5992..7743)
                     /locus_tag="NOA48_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0789988.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(7885..8109)
                     /locus_tag="NOA48_001731"
     CDS             complement(7885..8109)
                     /locus_tag="NOA48_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCI0789989.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            8360..9946
                     /locus_tag="NOA48_001732"
     CDS             8360..9946
                     /locus_tag="NOA48_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCI0789990.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(10255..12030)
                     /locus_tag="NOA48_001733"
     CDS             complement(10255..12030)
                     /locus_tag="NOA48_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCI0789991.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(12241..13143)
                     /locus_tag="NOA48_001734"
     CDS             complement(12241..13143)
                     /locus_tag="NOA48_001734"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCI0789992.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            13422..15767
                     /locus_tag="NOA48_001735"
     CDS             13422..15767
                     /locus_tag="NOA48_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0789993.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(15930..16196)
                     /locus_tag="NOA48_001736"
     CDS             complement(15930..16196)
                     /locus_tag="NOA48_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789994.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(16189..16512)
                     /locus_tag="NOA48_001737"
     CDS             complement(16189..16512)
                     /locus_tag="NOA48_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789995.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(16524..17780)
                     /locus_tag="NOA48_001738"
     CDS             complement(16524..17780)
                     /locus_tag="NOA48_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HCI0789996.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            complement(17777..18172)
                     /locus_tag="NOA48_001739"
     CDS             complement(17777..18172)
                     /locus_tag="NOA48_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0789997.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            complement(18526..19527)
                     /gene="ccpA"
                     /locus_tag="NOA48_001740"
     CDS             complement(18526..19527)
                     /gene="ccpA"
                     /locus_tag="NOA48_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCI0789998.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            19737..20840
                     /locus_tag="NOA48_001741"
     CDS             19737..20840
                     /locus_tag="NOA48_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0789999.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            complement(20903..21517)
                     /locus_tag="NOA48_001742"
     CDS             complement(20903..21517)
                     /locus_tag="NOA48_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0790000.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(21510..21959)
                     /locus_tag="NOA48_001743"
     CDS             complement(21510..21959)
                     /locus_tag="NOA48_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCI0790001.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            complement(22084..23022)
                     /gene="galU"
                     /locus_tag="NOA48_001744"
     CDS             complement(22084..23022)
                     /gene="galU"
                     /locus_tag="NOA48_001744"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0790002.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            complement(23037..24062)
                     /locus_tag="NOA48_001745"
     CDS             complement(23037..24062)
                     /locus_tag="NOA48_001745"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0790003.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(24106..24936)
                     /locus_tag="NOA48_001746"
     CDS             complement(24106..24936)
                     /locus_tag="NOA48_001746"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI0790004.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            complement(24951..25889)
                     /locus_tag="NOA48_001747"
     CDS             complement(24951..25889)
                     /locus_tag="NOA48_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCI0790005.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT         7468 a         5465 c         4688 g         8403 t
ORIGIN      
        1 tatcttgtca aaaaatgact ttattaagct atataacata aatccgttta caaatcattt
       61 tcaaaaaagt tataatttac gtaaaaaaac tagaagaagg tatctacatg ttattacgtg
      121 aaaaaatcaa agaaatctcc ttttctcctt cagaaaatga agtgattcag tttctcttaa
      181 gcgattctcc agcacttggc gaaatgacca tccaagagat tgctgagcga tgttatgtcc
      241 acccgtccac actcatccgt gtagcaaaaa aaatgggttt tgatggctgg gtcagttttc
      301 gtaatgcttt tttagctgaa acagcctatc ttgaagggaa ttttcaagac gtagatgcga
      361 atcttccttt ttccaccaca gacggtatta tgacgatcgc aaataaaatg gcttctttag
      421 aacagatgac gattcaagat acactttctc tcattcatca tgaccaactg caaaaagcca
      481 aacaactaat gcttcaagca aaaaaaatcg tgattttcgc cagtaactcg aatactttga
      541 tttctcaaga tttcatgctg aaaatgaagc gcatcaaaat ggatgtcacg attgtcacca
      601 cttttggtga atcgttctat gaagcgtaca attgcacgag tgatatgtgc gggattctga
      661 tttcttatac gggtgaaaac aatgtgatcc ttcgtaccgc agaaatattg aaacaaaatc
      721 atgttccaat tttagcgttg accagtatcg gtgattcaac gctatcctca atgagtacag
      781 ccgctttgcg acttacgaca cgcgaacgac tgtattcaaa aattggtaat tttacgatca
      841 atacatcgat ttgttatctt ctagacgtgt tatatagttg tgtttttgca gaaaattatc
      901 aacagaattt agtccatcta atttctgtag gacaaaaatt tgataaacgc cctatcagct
      961 cagccatcat gaaagagcct ttcaattttg aaaataaaga agtggactaa aaagaatagt
     1021 taagtctatt ccattctttc acctaaccgt tcaggtcagt gcggtgataa gtgcatcgtc
     1081 tggcccgacc gtctcccctt gattttccaa aatatccaaa taatccatgt aattggtgac
     1141 gattacaggt gtttctaaac tgtatccttc cttttcgatt ttctttttgt cgaagcggag
     1201 caacagatcg ccttgtttca ctctttctcc ttgctgcacc aagctttcaa aatatttccc
     1261 ttccaactga acagtatcca atccgacatg aatcagcaat tccagacctg tttcagaaac
     1321 cattccgatt gcatgtttcg tggggaacag ggtcatgact gttccgtcaa aaggggcacg
     1381 tacttctcct ttttcagggt agatcaagat tcctcgacct agtgttcctt gtgcaaaagc
     1441 tgcatccttt gctgctttca gtggagcgat ttgtccttgt atcggtgttt ttacaatttc
     1501 tttacctgat cttttctgtc tgtcatctgt ttcacctgct tcctccttcc aaaagaaaaa
     1561 agtcagcgca aaggatacca ccatcgcaat ggcgatccca atcaatacat taatcacatc
     1621 tgttaaatca ccatctggtc taatatagtt gggaattgta aagatgccta gtccaccttg
     1681 attccaagaa gttaaattca ttaacccact atacgcgccc cctaacgcac caccgacaca
     1741 agtaaaaata aatatttttt tacgtggtaa tgtaaaccca taaatagctg gctctgtaat
     1801 ccccacaata ccagaaacaa tggctggtat tgcaattgct ttgtcttttg gatttctaag
     1861 cttaaagtag agtgcggtaa gtgctgcagt ttgtccaaaa gacactactg caacaggtgt
     1921 cataatattt tgccaaccat tcacagaaaa ttgcatcaat cccattggta cgattgccca
     1981 atggagacca aacatcacca gaatttgcca gaagaagcct acgattgctc cataaataac
     2041 tggcgaaagt gctaaaagtg tttcaaatcc agccattaaa atatcagttg cgaatgtgaa
     2101 tactggtcca acgagtaaaa aacctaaagg cattgtaata agaacggtga agaatggaac
     2161 gaagaaattc gcgatcatct caggtactaa ctttttaatt ggtttctgaa tttggctagc
     2221 taacaacaca ataaagataa tgggaatgac agaagaagcg tagttacgcg caatccaggg
     2281 aatgccgaat actgtttgat aaataggtgc ttcaaaaata gtgccagaaa atatggtcgt
     2341 tagtggtgct tctgctgcac cactcaaagc ttccagcgac aagctaggat tcattaatgc
     2401 tgcgccaagc aacatcccta cgaattcatt tactttaaat ttacgggcag ctgttaaacc
     2461 gataataaca ggcataaatt ggaatacaga atcaccgata ttatcaaaca taacaaatgt
     2521 gccagaaccg cggtcaaacg cgcctaagaa gacaaggaat gctgtcagtc cacgaatcat
     2581 cccgccagca gctaagatag caaggaatgg ttggaaacag cccgatattc catcaataag
     2641 catatcaaac ggtctcattt tttctgttga aacagcctca tcaaaagtaa ggtttcctgc
     2701 ttttataacc tcttcaaaca cgactggcac atgattcccg atgacaactt gatactgccc
     2761 tcccgctcgc attaccgtta caataccgtc catatttttc aagatctcat catttgcttt
     2821 ttcttcgttt tttaatttga aacgaagcct tgtgatacaa tgtgtcaaac cattgatatt
     2881 ttccttccca ccgacatttt ctacgatttt tctcgctaat tcttggtatt ttcccatttc
     2941 tattccctcc aatatattag tggaaggttt agccaactga atgtcactac ccttatttca
     3001 tacgttcttg ttaatttatc ctcctttttt tatttattta caacgattct catgcactaa
     3061 acgcgcagta tggatcgtta aatacatttt ttcgtccgtg gacatctggt agttgaacgt
     3121 ctcggctaaa aagtctgcta ttttctcaac gcaaccaaac gtatccttat attttttttg
     3181 aataacctga aacaattcct cagaaacttc tcccacttct gatttttctc catctaggac
     3241 gcgtgtcaga aaaaaacgta agtgtgtgac gaatcgaaaa aaatggactg aatcttcatc
     3301 aaatgtaatc ttatagtaat agcggacgat atttagaata tcctgtattg ttatagtaaa
     3361 caggtaggta ttgttttgtt ggctttgaat gccttgtgca ttgactaaat gcaatgcgat
     3421 aaatccggct tcatcttctg ataacttgat gtggtattta tccgagattt tcttcactgt
     3481 ttttttcccg atggcatact ctttaggaaa tagttgtttg atatcataca gcaatacatt
     3541 tggtacaaat attcccattt tgtgacgttc gatagccgta tacaaatgat ccgtcaatgc
     3601 aatatacaca gaatcattca actggacttg tagagcctct tttgtatatt caatgatttc
     3661 acaagaaatt tctaagtact caagaggaat cgcttgtgcc aattcttgga actgttgtga
     3721 aagcccgtca tttgtcaact gaaatttttt gtcgatgcat gagtcaaaaa tcgggtcacc
     3781 cactttcttt ttgaatgcca aaccttttcc catcacgatc atttcctgat ttctttcatc
     3841 cctggttatt acgacgttgt tattcagtac tttctcaatc agcatgtttt gctcctttcc
     3901 atgatatata gggctgtatt caaaacaaaa agaaaaaccc aaaaagccgt ccatggaacc
     3961 atgggagact catcaggttt agcttgcatc aggcaatcac tatccaagtt gtatcgtttt
     4021 ctttatatta tcgaaagcaa acgctttctt agtggctatt aggcactttt gactagctgt
     4081 cgtcgtcttt tttaaatcgg gtgactacgc cactaacgct cacagatgaa gaatctggga
     4141 agctctgttt tattttcact ctagcgctta ggacaaaatg ctactatgct actgtcacaa
     4201 cctcttttta cacaccactg ctttgcagtt tgtacatatc tgcatacaaa ccattttgcg
     4261 ctagaagtgt ttcatgattc ccacgctcta ctatatgacc tttgtctaaa actaaaatca
     4321 attctgcatc ccgaatcgtg gacagccgat gggcaatcgc aatcgttgtc cgtccttgtc
     4381 gcatttttgc caatccttct tggatcaatc cttcggtttc agtatcgata tttgctgttg
     4441 cttcatccaa tactagtatt ttaggatctg tcacgattgt tcgcgcaaaa gtgatcagct
     4501 gtcgttgtcc actagaatag ctggcaccgt gttcgatcac ttttgagtga tatccttttg
     4561 gtaattcatc gatgaacttg tttgcttgaa caaactcagc tgcatggcga atctgttcgt
     4621 ctgtgatagc tggattcatc atccggatat ttcctgcaat atctccataa aacaagaagg
     4681 catcttgcaa gaccaatccc attttcttac gtaactcttc cattggatat tctcgaatgt
     4741 catgatcatc aatcaagatt tggccttcat aaaattcgta aaaccgcatc aatacgttga
     4801 tgatcgagct ttttccgctt ccggtgtgcc ccactaatgc aacggtctca cccggattag
     4861 cgacaaaaga gatattgttc aatacattgt gctctccatc ataagaaaag cttacattgc
     4921 gaaactcgat cttacctgaa gtaatcgctt gatctgctcc aggattttgt tgcggtgcat
     4981 attcttctgt atccatgatt ttcaaaatac gactaccggc aaccatccca tctgtaaagg
     5041 tgctcaaaaa gtccatcatt tgagacattg gattaaaaaa tccctggaca taggtcgtaa
     5101 atgcatagat cagtccaact tctacgggag aatgcaacgc atcgatccca aacaaagtca
     5161 acgccaacgc aatcgccaat gcatagagaa aattgatgat cggacttaac agaatcgaat
     5221 tcgttttgat catcgcatag cgcgtgtcta aatactcgtt gttcacttgt tcaaattctt
     5281 tagctaaacg agcttcttgg cgaaactgct ggataatacg catgccggaa atcgattcat
     5341 tcaatttcgt gttcagctga cttaattttt cccgcatatt tcggtaaata cgagaactga
     5401 atttctggta ataccagatg acgattccta aaatcggcaa gaacaccaaa gtccacaagg
     5461 caatttctcc attgatttga aacatggcaa cgaaagaaga aacgactgca aagatcccag
     5521 tcaataccat caaaaagaca taccaaaatt caaatagcgt ttctgtgtca ttcgtcactc
     5581 gagaaacggt cgatcctgcc ggtgtctggt caaaataacg catacctagt gtatgcagct
     5641 tttcaaataa tcttacccga acatactgat aggtcttcaa tgaagccatg gaatacaaat
     5701 accattggaa aaaccaaatg atacttttga ctatgactcc aaacaagtac acaccagcaa
     5761 aaaacaaaat aacttgtgtc gtagctgact gtttagccag atgatcatcc ataaaagttt
     5821 ggatgatcct tggcaatagg acattgatca cagacagggc aaacgcaaat aagatagcaa
     5881 cgatgaacgt tcttctaaaa ggtttggcga acttcatcag tcgtttgatg atcttcttct
     5941 gttctttaag tggaatcgat tttgtccatt ccgattgata attttcatcc atcaggcctc
     6001 gcctccttct atcttcgctt ctaattgctg tttttcccac attcgttcat accagccacc
     6061 taatgcaagc agctcgtggt gggttcctcg ttcaatgatt ttcccttgat cgacaacaat
     6121 gatttctttt gcatgcatca cgctgcttaa acggtgagct gcaatgatgg ttgttttctc
     6181 ttttcttatt tcttttaaat tatgcaagat agcttcttct gttttggcat ctactgcaga
     6241 aagtgcatca tctaagatca gcaattcagg atttttgatc aatgctcgag caatcgaaat
     6301 cctttgtttc tgtccgccag ataaagagac tccacgttct ccaactaagg tatcataacc
     6361 ttttggcaat tccttgattt cattgttgat aaatgctaaa gaagccgcat gctctacttc
     6421 ttcttctgaa agttttggat tagaaaaacg gatattatct cgaatggtca tcgaaaacag
     6481 gaagtgatcc tgaggcacat aaccgattga tcctaataaa gcattcaatg aatattcttt
     6541 gatcgaacgt ccgccaaatt ggattttccc ttgataatca tcgtattcac gcatcagtaa
     6601 tttgatgatt gtcgtttttc ccgcaccagt tttcccaaca atacctaatg tttctccttc
     6661 ttggatcgca aatttgattt gttctaatgc tggtgattct tctttcggat agttaaaaga
     6721 ggaaatagct acattcagct cgccttttgc cggggtctgc actgcaccca gttgttccac
     6781 gatatgcgtc ttttcatgca aaagttcatt aacgcgatca taagaagcat ttcctctttc
     6841 caatacgttg aacaatcggc caatcgcaaa catcggccaa acaagcatac cgatataact
     6901 aataaatgag accatctgcc caatcgagat cgtgccttcc aagacatact ttccacctaa
     6961 aataattgtt gcaacataag acagaccgat aatcaaggta atgaatggat caaataagga
     7021 gtctaaaaaa ttgactcgtt tgtttttaat aattgcatct tcaatctttt cttcaaaatc
     7081 cgcgagatct tctttttctt gtccaaatgt tttaatgact ttgatcccag tgatactttc
     7141 ttgtgtctta tcattgatac tagaaaaagc ttcttgcgaa tcacgaaaag catcgtggag
     7201 ttttgacccc agcactcgtg aagtaacggc tagcaaaggc agaggaatca gcgcaatcag
     7261 tgttaagcgc caatcaataa acaaaatcat cgcaatgatc gttgttccgc ccgtaatcac
     7321 tgaatctgca aaggtcaaga ttccagctcc tgctacattc tggattgcat tcaaatcatt
     7381 cgttgcatga gccatcaaat ctccagtccg atatttttgg taaaagagat tgtccatttc
     7441 tgtaaaatgt ttgaatagct gctgccgaag ttctttctcc aaccgagctg cacttcccca
     7501 aatattcgtc cgccagatat aacgaaaaag atattgtaag aaagctgcaa ggatcaatag
     7561 taagatccac caagaaatga tctttattga taaattctta tcggcgatct catcaatgat
     7621 gatcccaatc acttttggag gaactaactg taccaaggcc actgcgaata gggagaaaat
     7681 cccaattaaa taatgtttct tttcctgacg aaaaaaccaa cctaattttc taaaaatcga
     7741 cattttactc ctcctttgtc tttatcaaga gcataggatt gtctgtcctt gtcttttttg
     7801 ctgaatagtc tgaatagtct aacaaattac gaaataaaaa acggactgaa aaaatcagcc
     7861 cgcaaaaagt ctttgggtca gaacctattt tttcccttgg ttcttcattt gctgcatcat
     7921 ctggcgaatt ttcttctcag atggtttttg ccccattgac atcatcattg atcgcaacat
     7981 gtcctcatta acgggaggat ttttttctaa atagtctttc atatatttac gcgctaggaa
     8041 aaagccacct actgcgccga ttagcaaagc aataatagca ataagtacga caatacctgt
     8101 tgataccata taaatctctc ctttctattt ccgaattgct ctcaatgatt tattttacta
     8161 aagtttattg aaaaaagaaa ggcgtattct ttagtttcat gcaaaaaata gtggtttttt
     8221 tagagaagaa caaaatttct ttcattaacc agcaagacac gccacgaaaa aaaattaggc
     8281 ataccgaatc tttttcttta attttttctt tctgaggtgt agaatgtaat cgtagataaa
     8341 taggaaaggt ggttttttct tgaataatca atccaacaaa caatttcata agcatcgact
     8401 tattgaacat acaaatggtt tatctttagc tgaagtaaat ggaacagtgg atgtaccaaa
     8461 gggaaaaagt ttttttaaaa cacttcttgc ttactctgga ccaggtgcat tagtagcagt
     8521 tggttatatg gatccaggta actggtccac ttcgatcact ggtggacaaa atttccaata
     8581 tttattgatg tcagttattt tgatgtctag tctaattgct atgcttttac agtatatggc
     8641 agcaaaatta ggaatcgtga cccaaatgga tttggcccaa gcaatccgag cacggacaag
     8701 taagacattg ggtgtcattt tatggatctt gactgaatta gccattatgg caacagacat
     8761 cgcagaagtc attggtgcag caatcgccct ctacttactt tttgatattc cattggtaat
     8821 tgccgtattt atcactgtgt tagatgtttt cgtcctttta ttgctgacaa aagtcgggtt
     8881 tcgtaaaatc gaagctttgg ttgtctgctt gattttcgtc attttattcg ttttcgtcta
     8941 tcaagttggc ttgtctaacc ctgattggca cagtttattt gctggcttta tccctaacag
     9001 tcatacattc tcagactcac ctgtcatagg tggtgaaact ccgctgactg gagcgttagg
     9061 gattattggt gcaacagtca tgccgcataa cttatatctt cattcagcag tttctcaaac
     9121 tcggaagatc gatcaccaag acgaagaaga tgtagcacaa gcggtacgct tttctacttg
     9181 ggactctaat atccagttgt caatggcttt tttagtcaat gcactgctat tgatcatggg
     9241 tgtcgctgta ttcaaaaccg gttctgtcca agatccttcc ttttttggtc tgtatgaagc
     9301 tttatctgat ccatcagcta tgagcaatgg tatcttgatt gctgtagcaa aatctggtat
     9361 cttgtctact ttatttgctg tagcacttct tgcttctggc cagaactcta ctattactgg
     9421 tacgttgacc ggtcaagtca tcatggaagg attcatccat atgcgtatcc cgatttggct
     9481 aagaagacta gtcacacgat tgctttctgt gattcctgta ttgatttgtg ttttgtttac
     9541 aagtacaaaa ggaacgatcg aagaacatac cgctttgaat aacttgatga atgaatccca
     9601 agtttttctg gcttttgcat tgccattctc gatgattcct ttactgatga tgaccaatag
     9661 ccaagcggag atggggagcc gattcaaaaa ttcatttgtt gtaaaacttc ttggctggtt
     9721 ctctgtgatt agtctgactt acttgaactt acgaggatta ccaggtcaaa tcgaaagttt
     9781 cttcggcgag caagccacct cagctcaact agcattggct gatcaaatcg cctatgtaat
     9841 cattgttctt gtccttctcc tgttggcatg gacgattggt gatttatata aaggaaacaa
     9901 aaaatatgaa cagcgtttgc aagaaacgat agaagaaatc gaatagaaac tgattctttt
     9961 acacaaagga ggttgtgaca gaagtgggca gcttcaagaa ataagaagga atttaagaaa
    10021 attgcttttc aaatttttgt gaaatttcgg cttatttccg aagaagttac ttctggaaca
    10081 ccgtgtatca gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
    10141 aaatagttcc tcatatttta cgtttggttg agcttattac cgcagatgca agcttttgag
    10201 caccgtttat tcggaaaaag gaactgcgac aagacttttg tcacagttcc ctttttattt
    10261 ggaagataaa gcttttttca gattcaattt actaaaaact agcatgcttg ttactgcgat
    10321 gaattgcgtt aatggcacgc ctgcgccagt gtagacactt aaaaaataat cctttttttc
    10381 tggcgcataa gaacaaaacc acgagacacc gaaaagaaaa accaattgtg tcagtattaa
    10441 tccgatgact acaatcaaag aggaactata ataggcacga tcagcttttg caaatacggt
    10501 tcctagtatc ataagtaata tccctgctat tgaagcaatc agcacgggaa tggccagaac
    10561 ttggtaaatt tttatcatga cattcgcgac ttttgctgtt tttgtcaact ggaaatcagg
    10621 tgttctcgga tcactgctat cgatccaatt atccattagt ggaagattca ataattcttg
    10681 tgcctgttcg acttgttctt gcgtcccaaa actataattc cccccttgat ggaaatcttt
    10741 gtatcgccat gcataagcat atcctgattt cagaaaatca aatacgattg gcagatcatt
    10801 catcgtcttt ccatcccctg atcccatcag atagaattct tttttctttt tgatagttcc
    10861 cttttgatag gcttcttcta attcttgatt gacttttttc caaaaatcat tggtttcttt
    10921 tgcattgttt tggtaataac cagattcgct taccacatct cgcaatgccc aaaaaatgat
    10981 atctcctggt aattctttta cttttccgcc ttgggtccac gcatgagtcg tatacaattc
    11041 gtcaatacga gtagaaacag tatgaaatgt aggagatgcg tctaaagctt tatttaatgc
    11101 agcatgcgag acccatatct cactgttttc tttatttaag tttgtttcgt catctattcg
    11161 gatcagctgt ttcatcaaac gtccaaattc gccactcgaa cggtcattga tggctgcaat
    11221 accatatgtt gtctcgtttt tatattcgat ccactgatag acgatggaga aaccgactag
    11281 agggagtaaa aacaatgaaa gtttcagcca ttcttgtttc gaaaggagaa atggtcgttc
    11341 ttttaacttc tttgcttctt tgaaagaaaa gtcttgtcct agcaagatct gaacgaaact
    11401 gatgcctaac gcgactacag taaaaggaag aagccagatg gaatcttcgc gaatgaacca
    11461 aaagaaagga aaagaaacag ctagccctaa aaaccacggc agcaattttt tgctggaatt
    11521 atatttgcgg taataaatag ctagtaaaca agcgataatg atctcaacag tcgggatcac
    11581 gagagcatta cgatatgttc gagtggaata ttcatgtgta aaactaatcg gagaaaacaa
    11641 aaaataaaaa tagatactta aaagaagata cttgttcttc acgattggtt taaacgctag
    11701 tgcaaccaat atactggcaa gaatactgaa catgccgaat aaaactgcat aagaaagatg
    11761 cagtttatgt gcaagtacta aaaacaagct gtaggaaatc ccttttgaaa gtgtcgtagt
    11821 cgtgtactcc cctagccatt taccatccaa aatattttga gcatagtgaa tcagcagctg
    11881 atcatcatag gtcgccgaca tatctgttcc atagattgct ttactatata aatacaaccg
    11941 aataattgta aataatacgg ctatgccaag aataaagtat gtatgtttct tttttagttg
    12001 gtcgatcaag gggtttaaaa tgttcagcat cttttcgtcc tttcaatcac gttttgctac
    12061 ttgtttgtga aacttttcgt tttttacttt tctatcagta taccctgttt gtctgaattt
    12121 aaaaagaggg ggcaaaagga gcatggcgaa aacgaatgca aaaagcactc ctttgtttct
    12181 taaacaaaaa aggacaaggc agactgccca atcctttttt gttgctgtca ggtagaaaac
    12241 ttaaagtgtg acttcttctg ctaataactc agggaacact tcgggatcga atgcttgcgc
    12301 tttgaacatg gaaatttctt ttccatatgg tgcgtaagct ttctttttat ctttaccgac
    12361 atatggggtt tctaatattt tcgaaatgtt gtcaaacatt ggatcatgga cgattttgtt
    12421 caatgtgtca aatccaattg ttccaaaacc gatattggca tgccgatctt tatgagaacc
    12481 ttgaggattt ttagaatcat tgatatgcag tactttaagc cgatctaatc cgatgacctt
    12541 atcaaactct tccattacac ctgaaaaatc ttcttttata ttatatccgg catcattcgt
    12601 atgacatgta tcaaaagtaa cggataattt ttcattcaat tttactccat cgatgatttg
    12661 cgctaattcc tcaaatgttc gaccgatttc cgtacctttc cctgccatcg tctccaaagc
    12721 gatctgtgcc gtctgttctt ttgtcaaaac ttcattcaac ccctcaataa ttctagcaat
    12781 cccagcttct gcccctgctc ctacatgagc gcctgggtga agggtgattt gagtagcacc
    12841 taaagcttcc gcacggacaa tctcttctct cagaaattgt acagcaaatg gaaacatttc
    12901 tggtttgatc gtatttccca aattaatgat ataaggcgca tgaacgacga tatttgttag
    12961 tccgttttct gccataaatg cttttccggc atcaatattc atctcttcga tagcttttct
    13021 tctagtattt tgaggagcgc ctgtatagat cataaaggtc gaagatccgt aactggctgc
    13081 ttcttctgcc gcgcctaaca gcattttctt tccgctcatg ctgacgtgtg agcctaataa
    13141 catggatgga ttcctccttg aaaggcaatt gtttcgaaca attcctgtat attgataaga
    13201 tgatgtacaa agaaaatagt ttgtttttct ttgccctgtt ctccatagta actgaaactt
    13261 tccctaaaga aaagcttaag aactctttca taaaaaagat catttcctca cgttttatct
    13321 cattcgaaaa agaaattcct gtcaaaaaca gccttgtctg tttttttgtc ctattatttg
    13381 ctataattag cgaaataaaa ccattagttg aggtgaccct tttgccacgc aaaaatactc
    13441 gaaaaaaaca gaatagaaga aaaaaagaaa aatggtttgt tcctaagatt atttttagag
    13501 tgtttcaatc attgactgtt tttattactg ttcttctttt gttgttcgca gctctaggta
    13561 tcggaatagg tgctggctac tttgcctatc ttgtcgaaga cacacaattg ccgactaaaa
    13621 aagaactgca gacagaacta ggaaacatta cggaaacgtc aaagattgtt tatgcagata
    13681 atacagagat atcaaaaatc cagacagatc tgatgcggac gactatttca tctgataaga
    13741 tttcgccttt attgaaaacc gcgattatca gtacagaaga tgaatacttc gataaacacc
    13801 aaggttatgt ccctaaagct gttttacgag cactagtttc agaagcgact ggcatcggct
    13861 cgtctggagg atccactttg acacagcaat tagtcaaaca acagatccta accgatgaaa
    13921 caacattcaa acgtaaagca aacgagatcg ttctttctgc acaagtagaa aaacactttt
    13981 caaaagatga gatcattact acgtatttga atgtctcacc atttggtcgg aataataagg
    14041 ggcaaaatat tgctggagtc caggaagctg ctagaggaat ctttggtgta gatgcaaagg
    14101 atgtgactct gccgcaagct gcttatatcg ctggtttgcc tcaaagccct atcacgtata
    14161 gtccatacac gaatacaggc gcgctaaaag aagatctttc tgccggtctt gccagaaaag
    14221 attttgtttt attcagtatg taccgtgaag gacaaattac gaaagaacaa tacgaagaag
    14281 cgaaagccta tgatcttaca aaagactttc tcccacaaca aatcgcggaa cagactgaca
    14341 gagaattctt gtattatacc gtgatgaacg aagcaacaag gattattgca caacaattgg
    14401 cagaaaaaga taatgctgat atgtcagatt catcggtcag tgaagcttat tatcaaaaag
    14461 cacagcaaac gatccaaaac aaaggatata cgatccattc gacgattgat aaagatatct
    14521 atgctgcatt gcaaaccggc gtagaaaatt atggctacat gttagatgat ggtgctggta
    14581 gccaagtgga gactggaaat gtattgatgg ataacagaac cggacgtatc tatggcttcg
    14641 tgggtggtcg gaattacagc cagaatcaaa ataaccacgc ctttgataca gaacgtcaag
    14701 ctggttcatc catcaaaccg gttcttgttt acggtcctgc aatcgatatg ggacttgtcg
    14761 gatcagaatc ccgtgtatca gattatgcaa cgacttggca agaaggaaaa aatgctggtg
    14821 agaaaatcgt caatgcgacc aatgaagggt cgaacacctt ccaaaccgtc cgtgagtcac
    14881 tggaatggtc caacaatatc ccagcttatc acttatatca agatgtgttg aattccggtg
    14941 gatcgaaaca atacgcttac gagcactact tggcgaagat gaactaccca gcaaatgata
    15001 attggggcgt tgaatcggct cctttaggga cagtagatgt aacgacgctt caacagacaa
    15061 atggattcca ggccttagca aatggtggag tctacgaaga aggctatatc attgattcca
    15121 tcacagataa tgcaggtaat gtgatttata aacatgaaag taattctgtc cgtatttatt
    15181 ccgaagcaac ggcatcgatc atgaatgaca tgatgcgtag tgtgatcaat gaaaaaatca
    15241 ctacaccatt caaagatgtc atctcaagct taaacggaaa tctaggaaat gcagattggg
    15301 tcggaaaaac tggttctacc aatgaatacc gagattcatg gctgatcgtc tcaactccat
    15361 ctatcactat cagtagttgg gcaggacacg atgacaatac tggaatggac agccaagcaa
    15421 gaatacgttc ggctaattat cttgccaatc taatcaatca agcttaccaa gcaaaccctg
    15481 agattttcgg cactgatgag aaatttgact tatcatccga tgtgatgaag aaaaaagtat
    15541 ctgggttcac aggacaaaca gctggaaaag ttactgtcaa taaaaaatct atccaaacgc
    15601 caggaaaaac agtggaatca ctttgggcaa aaaatggtcc gaagaaaagc gcctttaaat
    15661 tcggcgttgg cggtactgat gaaaactata cagattactg gaacaccgct tcagcttatg
    15721 ctagagcgaa tccagagacc aaagaatcag acgataaaga tgattgatct aatagattaa
    15781 tcagaattaa agggagctgc gacaaaaatc ttgtcacagc tccctttttc cgaataaatg
    15841 gtgttcaaaa gcttacatct acgatattaa gacaaattta tgtaaaaatg tgaaaaacca
    15901 ttttcacaaa atttttctat ataactttac taacgaaact gttttaattt cttttcttgt
    15961 ctttggaata attcggttag tttttctgca aattgccctt ttactgattc ttttaagtgt
    16021 gcatgtcggt tagaaaattc ttgagtagct tcttctgcag tcatttggtg gttttgatct
    16081 gtcaatcgtt tttctgccca agtttgctga gatatcccca taccaactga acgtacattt
    16141 gatcgatgta gatttttctc taattctttt agtaattgca ttaaaaattc attcataaga
    16201 tgatttctcc atagttattt gtctgatttt ttgacgatag gaacgttcta gttcgtcttg
    16261 ctgctgatag agttttcgtc gttctacttg tagggcttgt tgataatgct cctgataatt
    16321 cgaataactt cgtcttgctt gaaacagagg ctcattatct aaagctaagt tctttaatac
    16381 atgatgcagt cgctgctcct cttgctccat caatcgtaat ccttgattct taaagtggat
    16441 caattcatct tcttgagctt ctaattgtct tcgttcactt cgataatctc tttccaattc
    16501 ttctagtttc atctacttct cctttaattg aattgctgtg ctaattctcg atctcgtgcc
    16561 acgatttcat tgattttgtc ttggatctcc ttcgccaatg tatcaaaggc ctcccccata
    16621 cgtcttgcct tattgattcg tagcagatag acttctttcg cagaatcgac taagttctct
    16681 tttgtggcgc ccacactagc taatgcttct atgatttcct gttcagtcaa cgaaggggcg
    16741 acaacacgtg cttgccgcaa gccttcttgc cattttttct ctagctcaaa aattcctctt
    16801 tggttgatgc ggataacttc ttccatagcg cttttcattt ttaccgataa cttttccacc
    16861 actaacctag cttgtgtgtc atctaagtaa atttgttcat taactgtcag ccggccgcca
    16921 cttaatcgta gttttttacg tatgttgttc agttcttgca actgatagga aaacaactgg
    16981 gtcgcttggt tttctttctg ttgttttcga gctttaacat tgttttcatt ttcaggaata
    17041 atcagctttc cattttcatc aaacttccaa gaggttaaac tgtgggaagc aagcagattc
    17101 aagtatgctg tttccatact gatccgaact tcagcacctg tgccattacc accaaaatta
    17161 ccgataaaat cggcgtgatt tcggtaattg gtgagcatac cgggattttc ttccacccat
    17221 ttttttgctt ctggtgataa gagatcatac gggtccggcc cgttgaagcc gacatttttc
    17281 cattgtttct ctgctgctac atataatgct aagaatccac ctaatgaatg gccggtagta
    17341 gaaatagcag cttctccata ttcctttttt acttcattag caaatgcaat cgctgaattg
    17401 atttgccccg ctgttttcaa tccactaacg gataaaatct tgtttgttgt tgctttttca
    17461 gaaaaacttg ctcctggtct attcccatag agattcataa cacttcttgc atccgtttcc
    17521 aaatctttcc aatcgcttaa gttcgttcct gcaaaagcaa tcactacttg agaaatatcc
    17581 actttaccgt tcttgattgg cgctacagcc atcgcctgca tgccgtcgaa ggagtttttg
    17641 atttttagga tttggaattt tgtttctcca aagtttttaa tggcgccttc tttgtaactt
    17701 ttactatatt gaggatgttt tggatctagc caatatactt tattacttat tcctttatac
    17761 tgcttatcag taattgtcat actttttcct cactcccatc tgtatagata actataatct
    17821 catcaaccgt aatcccttct ttttgtactt cttcattttc aacaccatag ccatctatct
    17881 cattgctttc ttttgtaaag ctataatcaa aataaacggc ttttccttct gtattggtca
    17941 tcgttatcaa tgcttcatag attcctgtca tgtcgttttt ctcaaattgt tcgattttca
    18001 cttctttgat atccgcaaag gtatttttca gaactttgac ggactgtttt tctactgcga
    18061 gtaaatcttg ctgtttttgc gcttctcttt tgtccatgta aaattttcct ccgattccta
    18121 tagtaagaat ggtcaaaatg atgactatgg tctttcgtct tttcttaggc aaatagaagt
    18181 ctcctttcgg gttatgtatg atggattgtt tctcctttaa gataagtacg caatcgagcc
    18241 tggatttttt tggatttttt agagttactt ttctactttt ctactttctt ttttatcacg
    18301 ttttcatttt aaagtaattt tgatagtagt gaacaaaatg tagcatctac gcacagattg
    18361 tgtcgtatac gatggacgta aggtttgttt ccgccattct ctcttttttt taaagtcaca
    18421 aaaaaagggg ttatgacaaa attttgtcat aacccctttt ctcgtataaa ggttgttcca
    18481 gaagttgacc actttgggaa caacctttaa atgattgatc ttttattatt tagttgatcc
    18541 tttttcttcg attccataag gcaagataat cgttttttct tcgacttctt ctttattcat
    18601 cattttcgtc aataggcgca tggataccgc tcctaaatcg tataatggtt gtgtgatact
    18661 tgtcaaacga ggacgagcta cttctgtcag taaagaattg ttgcttgtga tgatttcgaa
    18721 ttcttctggt acttttacgc cgcggtctaa taaaccatcc aagataccaa tggctaattc
    18781 atcgtctgaa acatagacag ctgttgcacc gctattatgg atccggtcaa ctagagacag
    18841 accatcttta aagttgtatt gtgcctcaaa aatcaatcct tcgctatatg gtagattgtt
    18901 ttcgcttaat gcttctttat agccttttag acggttttga ccattgatag gatcaatcag
    18961 cgcaccgctg acaaaagcga tttttttatt gccgcttttt gctaatttat ttactgcatc
    19021 ttttgttgct gatacataat caatgtttac gctacctact tgttcatctg gatcaatgga
    19081 accagctagt acaacaggcg tttttgaacg tgaaaattct ccacggattt cgtctgtgat
    19141 atggtgaccc ataaagatca cgccgtccac ttgcttagcc aataaattat tcaatacatt
    19201 gacttctttt tgatcgttgc catctgagtt tgctaagatg atattgtatt tgtacattgt
    19261 tgccacatcg tcgataccac gtgctaaaga ggcaaagaac atattgctga catcaggaat
    19321 gattacccca actgttgttg ttttcttact tgccaagcca cgtgcgactg catttggacg
    19381 ataatccaag cgatcgataa cttccaagac tttttttctt gttgctggtt tgacgtttgg
    19441 attgccattt acgacacgtg aaacagtagc catcgaaaca tttgcctctc tcgctacatc
    19501 atagatagtg attgtttgct tttccatttg tgttctccta ttcatatttt atatgttttc
    19561 tgaaaatacg tcttacattt ctaaaatagg atatcaaata atctcaacaa ttgcaaccgt
    19621 tttatctctg ttttcatgaa aatttttact tttttcagtt ttaagaacgt tggtctttta
    19681 atcaatcagt ggtacaatta ttgaatacaa aattaattta gaaagtaggt tgccaaatga
    19741 ataacgtaaa aatcaatgaa ctacgtcaat ggatggcaca acaccaatta gaattggctt
    19801 atatcagcga ccctggccac atcgcttact tttccggata tgaaagtgat cctcacgagc
    19861 gtgtactagc tctttttatc cctctggaac aagatccttt ccttttcact cctgctctgg
    19921 aagttgaaga tgctcaaaac agcagctggg cgtacgatgt acgtggctac ttagacagcg
    19981 aaaatccttg ggagatcatc ggaaaagagc ttcgcgcacg ctatgggcaa cctggtaatg
    20041 taggtattga aaagaatgct ctgactgtcg atcgcttcga tgctatctct gatatcttga
    20101 caggtacaga ttcttacacc gatctaactt ctattatcca gcgtctgcaa ctgatcaaaa
    20161 cggtagaaga aaaagacaaa ctgatcgaag ctggtaaatg ggccgatgtt gcctttgaaa
    20221 ttggcttcaa aacagtaaaa gaaggcgtaa ctgaacaagc aattatcgca gaaatcgaat
    20281 accaattaaa aaaacaaggt gtttcacaaa tgtctttcga cacattagtc cttgcaggag
    20341 caaatgctgc aagccctcat ggtacaccag gaagcacgaa ggtttcacca aatgaactag
    20401 tgttattcga tcttggcgtt atttggaatg gctattgcag tgatgctact cgtacagttg
    20461 cttatcaaaa accaactgaa ttccaagaaa aaatctataa catcactctt gaagcacagc
    20521 ttgccgcaca agaggcagtt cgcccaggtg tgacagcagg tgaacttgat caaatcgcac
    20581 gaaacgtgat caacagctat ggctacggcg aatatttcaa tcaccgttta ggtcacggaa
    20641 tcggaacaac cgtccacgaa ttcccttctc ttgtagaagg aaacgactta gtgattgaag
    20701 aagggatgtg cttctctctt gaaccaggaa tctatattcc tgaaaaagta ggggtacgta
    20761 tcgaagattg tgtgtatgtg acaagtgatg gttgtgtgcc attcacgact acaccaaaag
    20821 aattacttgt tttagagtaa tgaaaataaa aaaggtgaga gctggtccgc tctcaccttt
    20881 tttattctag aaatgagtaa tcttagtgat tggtagtcga atctgtcatt gtatctttca
    20941 tttctttttt agcttctttt gcatcttctt ttgcatcttc ttttgccatt ttcaacattt
    21001 cttttgtgtc atctgcaact ggttttgctt ctgacattcc ttcattgacc gtctctcctg
    21061 ctttatctgc agcatctttt acatcgatca tgatatcttc tgaagtatct ttagcaatac
    21121 tacctaattc gtctgctggc tttttcagat cttctgctgt ttttttgaaa cgattagata
    21181 aatcagctga ttgttctttg aggtttaaca agatatcatc tgattcgctt cctgcttcct
    21241 ctgctgattc acttaccttc tgcttaacat tgcctgctag atcccctgct tgttgagaaa
    21301 gatcttgcgc tttttctttt gcaatacctg ttaactcaga tgatttttct tttgccatat
    21361 ctgtgtaatc tgaagccatg tccatcaaat catctgcttg agcagccaat tcatcccgaa
    21421 gttctttacc agatttgggt gctaacaata atgcggcgat tgctgcggct gtacctccaa
    21481 ctactgcacc taataaaaat ccaccttttt tagccattct tattttcctc ctgtcgtttc
    21541 agtatgtttt ttgtttttaa aaatttcatc gctgttccac cgacttttcc ggcaacagtc
    21601 gctttagctg tcgtttttcc gattccgccg actttcgtca cgatgttttt actagaatga
    21661 ttaagttccg atacactttc acttaaatca gcaactgctg tgaacaatgg atcgatcgtt
    21721 gcgacttttc cattgatatc caagagcagc tcattacttt tgactagcaa gccttctact
    21781 tgtctagata aaagatctac gtcttgtgtg acgatctcaa ttgtcgtatt tgcttctgcg
    21841 acagtctggt ctactttttc taaagttttg gaaacttgca acaatacgcg aacgatgaaa
    21901 acgacaagta tcgcaaaggc gattgctgcg atcaatcctg caatttctcc tcctgacatg
    21961 atcaaactcc cttcttgtct ctcttttcta taaggatagc attttcgtgt tttttaaaca
    22021 aataaaaacg agcttcaact actttttatt caattagcag ctgaagctcg ttagaaaaaa
    22081 agattatttt ttcttttctt ctttgatttc tgttattcct tttggattat gattgatctt
    22141 gcttccttct gcttctaatg ttttacctaa agacatgatg tattcacgca aaggtgcccc
    22201 tacttctgga tgtgtcagac catattcaat acttgttttc ataaaaccaa atttgtcacc
    22261 aacgtcataa cgtttacctg tgaatttacg ggcaaatacg cgttgtgttt tattcaacgt
    22321 atcgattgcg tcagttagtt ggatctcatt tccagcgcct ggttgttgtt ctgataatac
    22381 atcaaagatt tctggagtca ataagtaacg cccaataata gctaaatcac ttggtgcttt
    22441 gcttggatct ggtttttcaa caaagttttt gacattgtat aacccatctt ccagtacttc
    22501 ccctgggttg atgattccgt attttgaagt ttcatcgtga ggaacttgca taacggcaat
    22561 cgtagaagcg tgtgtacgct catagtcatc gatcaattgc tgtgtcaatg gtacttcgtc
    22621 ttccatgata tcatcgccta gcataacgac aaacggttca tttccaataa aggctcttgc
    22681 ttgaagaacg gcgtgtccta acccctttgg atgagattga cggatgaaat gcaaattgac
    22741 atctgtcgtt tcttctacta atttcaataa ttcggttttt cctttttcac ttaggtttgt
    22801 ttctaattcg atatttgaat caaagtgatc ttcgattggt cgtttagctt ttcctgtaac
    22861 gatcaagatg tcttcgattc ctgatttcaa cgcttcttca acgatgaatt ggatcgttgg
    22921 tttgtccacg attggcaaca tttcctttgc catcgccttt gttgctggta aaaatcttgt
    22981 tcctaatcct gctgctggaa taactgcttt ttttactttc atatacattc gctccttcaa
    23041 aaaattgtta atgagaattc attttctttt ttcccatcac gtaacatgat ttcttttgcg
    23101 gctgttttga tttctttttg ttcatacagc acttcataga ttgtttgagt gatgggcatt
    23161 tcgatttcca tcatttgggc tagttccatc gctgcttgag tagtattcac accttcaaca
    23221 accattccca tattggctag cacctcttct agaggctgac cttgtcctaa caagttgcct
    23281 gcgcgccagt ttctggaatg aacacttgtg caagtaacga ctagatcacc tactccgctt
    23341 aagccaataa aggtcagcgg gttggcaccc attgctacac ctaaacggct gatctcagct
    23401 aatccgcgcg tcatgattgc cgcttttgca ttatcgccaa accctaagcc gtgaatagca
    23461 ccagctccaa tggcaataat atttttcaaa gctgctccca tctctacacc aatcacatca
    23521 gggttggtat agattcgaaa ataatggttc atgaacagct cttgtacata ttttgctgct
    23581 tttacatttg tgcttgccgc tgtgatcgtc gtaatgtcat gctttgctac ttcttccgca
    23641 tggcttggcc cagaaagaac agcaacagct tttctttttt ctgtcgggat ttcctctaac
    23701 aagatttcag agattctttt atgcgttccc tgttctaatc ccttacttgc gtggatgatc
    23761 actggcttcg tattcaattt ggcaactagt tcttttgcaa cagaacgtat cgctttcgtc
    23821 gggataacga atagtaccgc atctgcatct tttactgcat cttccatatc ggtgaatgct
    23881 cggatggaat cgggtagatg atgatctggt aaataacgtt gattggtgtg ttgggtgttg
    23941 atttcttcta cttgtgaagc acgatgtccc caaatccgaa cgtcatgtcc gttttcagcg
    24001 aggacttgtg ctaaagcagt cccccaagag cctggtccta aaaccgctac tctataattc
    24061 attttaccac tcctgaaatt tttttcattt ttaacgctct gaaaatcaaa taatttgttg
    24121 attttttcct aatgagcggt cataatccgg taaacttcct ttttttctac gccaaataaa
    24181 cagaatcaat gtgccgacaa ataaaacagc agacaataat tgagaaatgc ggatcacacc
    24241 taaaaagtaa aggctgtctg tgcgtaaccc ttcgataaag aaacgtccga aactatacca
    24301 cattagataa cataaaagga cttctccttt tttcaaaaga tgtggtttct tccgcaaaac
    24361 caaaagcaga ataaatccaa tcaaactcca aagtgattca taaagaaagg ttggttgtcg
    24421 atagattcct tcgatataca tgttatcaat gatgaattgc ggtaaatgca gactttctaa
    24481 gaaacttcgt gtcgtgtctg gaccatacgc ttcgtggttc atgaaatttc cccatcgtcc
    24541 gattgcctgc gccaataata cgcttggtgc agcgatatct aaaaaggtcc acaaagaaat
    24601 aaaatgatat ttggtaaaaa agtacagtgt gattgcacct gcaatcaatc ccccgtaaat
    24661 cgctaatcct cctgaacgga tattgaatat ctggattgga tcagctatat attggggaag
    24721 atcgaataaa acataataca agcgggcacc aataatggaa atcggcaatc cccacaacat
    24781 aaaatctgtc acgtcatctg cttttaatcc tacccgaaca gcttctctgc tgctgagcca
    24841 catggcaata atgattcctg atacgataat caatgcatac cagtagatag gaattcctac
    24901 aagctcaaaa gcaactcgat tgatttgtgc taacatattg tcactccttg ctagtcattg
    24961 cctgagtttt cttcaatcaa gcgacttaat ctttcttcaa atgttttcgt tgcgtcaaag
    25021 cccattgtac gtgcgcggaa attcattgcg gctacttcaa tgatgattgc aacgtttcgt
    25081 cctgttttga cagggatttt tatttgtgga atgcccactt ccgcgatttc aacggtcgtg
    25141 tcttcagagc ccagacggtc gtatttctta tctttcgccc atgcttctag ataaacagct
    25201 aactggactt gcatagagcc tcgtaccgca ctcgcaccga aaagattcat tacatctatg
    25261 ataccgatcc ctcgaatctc aatcagatgt tccaggattt taggaggttc tccgattacc
    25321 gtcagttcat cttgctgata gacatctact cgatcgtctg cgatcaatcg atgtccgcgc
    25381 ttaatcagtt ccaacgccgt ttcacttttc cctatcccac tgtccccttg aattagtaca
    25441 cctaatccgt agacatcgac taacacaccg tggacacttg ttcgaggggc taagcgtcca
    25501 tctaaataac tagataattc acctagcagc cgggacgttg agataggcga acgcagcaca
    25561 gctatcccat tttcattggc tgcttggatc atttcttccg gagccggcaa tcctcttgaa
    25621 ataataaatg cgggcatatc ttcactacat aatcttctca taatgatcaa acgctcttct
    25681 gggatcatcc gttccgcaaa actgatttct ttactgccaa atagctgtaa acgattatgg
    25741 gaataataat taaaataacc ggtcaactct agtcctgggc gtgagatgtc cccagtcacg
    25801 atgacgcggt ctaaactttt ctcgtcgcct gtgacgattt ccaaagataa tttttttact
    25861 aattggctaa cttttacaac ttctgacatt catgctacct catttctatt agagtgttct
    25921 ctatcatttt atcattgtct agccaaaagt actaccaatt aaaaaaaacg tttttattta
    25981 attaccaatg taatagaaaa cgcattcttt attctaaaca aaaa
//
LOCUS       DAIGQM010000043        25500 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.043, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000043 DAIGQM010000000
VERSION     DAIGQM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.043"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            133..3660
                     /locus_tag="NOA48_001748"
     CDS             133..3660
                     /locus_tag="NOA48_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCI0790006.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="NOA48_001749"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="NOA48_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCI0790007.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQVIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="NOA48_001750"
     CDS             7448..7789
                     /locus_tag="NOA48_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790008.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="NOA48_001751"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="NOA48_001751"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCI0790009.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="NOA48_001752"
     CDS             9146..11566
                     /locus_tag="NOA48_001752"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCI0790010.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOA48_001753"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOA48_001753"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCI0790011.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="NOA48_001754"
     CDS             13000..13737
                     /locus_tag="NOA48_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0790012.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="NOA48_001755"
     CDS             13751..14566
                     /locus_tag="NOA48_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0790013.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="NOA48_001756"
     CDS             14579..15226
                     /locus_tag="NOA48_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0790014.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="NOA48_001757"
     CDS             15242..15898
                     /locus_tag="NOA48_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0790015.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="NOA48_001758"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="NOA48_001758"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCI0790016.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="NOA48_001759"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="NOA48_001759"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCI0790017.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="NOA48_001760"
     CDS             18240..18758
                     /locus_tag="NOA48_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0790018.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="NOA48_001761"
     CDS             18865..19365
                     /locus_tag="NOA48_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0790019.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="NOA48_001762"
     CDS             complement(19645..20565)
                     /locus_tag="NOA48_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCI0790020.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="NOA48_001763"
     CDS             20730..21743
                     /locus_tag="NOA48_001763"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCI0790021.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOA48_001764"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOA48_001764"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCI0790022.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="NOA48_001765"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="NOA48_001765"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0790023.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="NOA48_001766"
     CDS             complement(23383..24144)
                     /locus_tag="NOA48_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0790024.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="NOA48_001767"
     CDS             24333..25427
                     /locus_tag="NOA48_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0790025.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4423 c         5383 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagtcatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtggacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
//
LOCUS       DAIGQM010000044        25166 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.044, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000044 DAIGQM010000000
VERSION     DAIGQM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.044"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(71..472)
                     /locus_tag="NOA48_001768"
     CDS             complement(71..472)
                     /locus_tag="NOA48_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0790026.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(558..764)
                     /locus_tag="NOA48_001769"
     CDS             complement(558..764)
                     /locus_tag="NOA48_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790027.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(859..2361)
                     /locus_tag="NOA48_001770"
     CDS             complement(859..2361)
                     /locus_tag="NOA48_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCI0790028.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOA48_001771"
     CDS             complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOA48_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0790029.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(2932..3549)
                     /locus_tag="NOA48_001772"
     CDS             complement(2932..3549)
                     /locus_tag="NOA48_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCI0790030.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            3770..5143
                     /locus_tag="NOA48_001773"
     CDS             3770..5143
                     /locus_tag="NOA48_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790031.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            5218..6330
                     /locus_tag="NOA48_001774"
     CDS             5218..6330
                     /locus_tag="NOA48_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCI0790032.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(6402..8039)
                     /locus_tag="NOA48_001775"
     CDS             complement(6402..8039)
                     /locus_tag="NOA48_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCI0790033.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELYLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(8207..8815)
                     /locus_tag="NOA48_001776"
     CDS             complement(8207..8815)
                     /locus_tag="NOA48_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0790034.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(9199..10350)
                     /gene="queG"
                     /locus_tag="NOA48_001777"
     CDS             complement(9199..10350)
                     /gene="queG"
                     /locus_tag="NOA48_001777"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCI0790035.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTGIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(10369..11121)
                     /locus_tag="NOA48_001778"
     CDS             complement(10369..11121)
                     /locus_tag="NOA48_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790036.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(11262..12212)
                     /locus_tag="NOA48_001779"
     CDS             complement(11262..12212)
                     /locus_tag="NOA48_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0790037.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(12213..13052)
                     /locus_tag="NOA48_001780"
     CDS             complement(12213..13052)
                     /locus_tag="NOA48_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0790038.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(13049..13795)
                     /locus_tag="NOA48_001781"
     CDS             complement(13049..13795)
                     /locus_tag="NOA48_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0790039.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            14033..15403
                     /locus_tag="NOA48_001782"
     CDS             14033..15403
                     /locus_tag="NOA48_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0790040.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(15458..16354)
                     /locus_tag="NOA48_001783"
     CDS             complement(15458..16354)
                     /locus_tag="NOA48_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0790041.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(16468..16638)
                     /locus_tag="NOA48_001784"
     CDS             complement(16468..16638)
                     /locus_tag="NOA48_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790042.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(16635..17312)
                     /locus_tag="NOA48_001785"
     CDS             complement(16635..17312)
                     /locus_tag="NOA48_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0790043.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(17403..18308)
                     /locus_tag="NOA48_001786"
     CDS             complement(17403..18308)
                     /locus_tag="NOA48_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0790044.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIRVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            18483..19937
                     /locus_tag="NOA48_001787"
     CDS             18483..19937
                     /locus_tag="NOA48_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790045.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            19953..20984
                     /locus_tag="NOA48_001788"
     CDS             19953..20984
                     /locus_tag="NOA48_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0790046.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            20991..22178
                     /locus_tag="NOA48_001789"
     CDS             20991..22178
                     /locus_tag="NOA48_001789"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCI0790047.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            22334..23716
                     /locus_tag="NOA48_001790"
     CDS             22334..23716
                     /locus_tag="NOA48_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0790048.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            23843..24073
                     /locus_tag="NOA48_001791"
     CDS             23843..24073
                     /locus_tag="NOA48_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790049.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(24273..24941)
                     /locus_tag="NOA48_001792"
     CDS             complement(24273..24941)
                     /locus_tag="NOA48_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCI0790050.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         7028 a         5105 c         4684 g         8349 t
ORIGIN      
        1 tttgtcaaaa aaaaccagac aaaaagcggt cctttcacgt ttttagtctg gttcgatttc
       61 ctttattctt ctaaacaatc gttacttcta catcgatatt tcctctagtt gctttggagt
      121 aagggcagaa ttcatgcgca tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat
      181 cgatatgcac ttctaatact acaccgatct gatagccgcc atcatctaaa ttataaagag
      241 agacacgtgc ttttactgtg gactctgctg tcattcctgc ttctttgatc atatgttgta
      301 ccgccccatt gaaacaagaa gcataacctg ctgcaaataa ttgttctgga tttgttcctt
      361 ctgcatggat tcctggagga gtgattttca tatgcatcga gccatttggt gcctcgactt
      421 ctccattgcg cccgccatgg ttgatcattg ctgtttcgta tgcttttttc attgtactgc
      481 tcctttcgat tgaccatttg ctacttggct ataattatag tgtatgacaa gtaaggcgct
      541 ttctacaaaa attctgctta ttcgaatacc agaatgccgt cttctactat ttttccaaaa
      601 aacaaaaaaa tactactcgt gaacaacagc gtcatatttg ttccaaaata aatagcaatc
      661 ttttctacat aatcttttat atgattgatt ttaagataca tatataccag aaagttgacc
      721 ccataaacca atactgttaa aaaaataacc atattcgtta ccattttttc ctccttttgc
      781 tggtctccct accagcactc gatttaacca taccactttt tttgccgtcc aagcaactag
      841 cctttcaaaa agactggttt attctgctgt taatgattca agatcagaaa aatgtccgaa
      901 taattttgct aattttacta acgccaactt gttctttccg aattcatcat tttctatctg
      961 taatactagt aacggctcat gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg
     1021 ctcttctaga tcatatcgaa taccttcttc attttccggg tcgaagttca tccctttttc
     1081 ttcttccaac agtcgcttca tttcttctaa tatcttgttt ccttgttcgc gtggttcatc
     1141 gctgaacaat tttaatcgga tttcttgtac ttctacgggc tgtttcaact ctttgatttg
     1201 ttcatctaat gtgatacctt ttctttttaa ttctggcaaa agcatcagga tctttgcgat
     1261 gacatatgca ccatcatcca gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc
     1321 gatggctagc tgtgtatctt tcccaagacg gttaagttct aatgctttat tgattacatt
     1381 tcgatagccg gaaatataac gaacttggat gcctcctttt tcttcaatga atctttgtag
     1441 atgagaagaa gtaggggaat tcgtcacgat tcttgttcct ggatgctctt ttaatacgat
     1501 tgtacttaat actgcgatca aattatttcg attgatcact gttccagaag cactgacaac
     1561 tgcagaacga tccacatctg tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac
     1621 agcctgcttg atactttcca tcgcttcttt attatcagga tttgggatat gattaggaaa
     1681 tcggccatct ggttccaaaa attgggaacc tgttgaatcc gcacctaagc tattcaatac
     1741 tttttcagca aagaatccac cagcaccatt tccggcatca acaatgattt tccaaccatt
     1801 tagtggtttg ctttctagtg ttccaatccc ctttttaatt tttgtgacta aatcttgcgc
     1861 ataaggtgtc aaaaggtctg ctttttctac gcttccagtt tgttcgcttt ttattttttg
     1921 ctgctgtgat aggataaaag caatatcttc tttttctgct cctccttctg aggtaaagaa
     1981 ttttattcca ttataataat agggaagatg gctagcagtc agcataaccg cagcatcgca
     2041 cgagaactgt tcaaattgag tggacataaa catagcaggc gtagtagcta attcgaaatc
     2101 gatgacatgt atcccttgtt ctttcagact ttggatcaac gcctctttca gtgctggtcc
     2161 gcttatccta ctgtcatgac caatcccaat cgtccatttt ttatttggat cggttgattt
     2221 cttctttttc tttatccagt ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt
     2281 caagtttact tcatatcctt caactggtaa tgcgattcct cgaatatccg atccattttg
     2341 cagcgctttc atatctttca tataaaagtc ctcctcattt attccctcat tttttccagc
     2401 ttttctgcaa atcgctgtgc ttcttcttct gagcggcaaa taataatgaa tgtatctaca
     2461 ccggccatcg ttccgacaac ttcagggtaa gccacttcat ctagccaatt cgttaccaca
     2521 tcggcaccat ttcgttcagt caatacgata accatgaact gaacagactg gatacgcaaa
     2581 acctcgcgtc taattgctgt acgcaaacgt tcttcattta aagaaacaga tggctggtta
     2641 aataatgtat agcgtactat tttgttttca ttttgacttt ttactaactt catttctcga
     2701 atgtctcgag aaatcgttgc ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc
     2761 agctcttcct gtgtcccaat aggttgttct gtaatgatct ggcggatcag tgcttgtcgc
     2821 tgtttctttt tcatattaga cacctctcaa tgttgattat agcaaaagat aagtaatatt
     2881 tcttcatatt ttggtatttt ttacttttat tttttgtttt cattcaggtt gctaaccttt
     2941 ttctatttta acacgcaaaa tcgtcttcat tttttcaggt gctgattttc ttggatcgct
     3001 gatgtaaatc tctttgtgtt ctttagaagc tctttcatag ccttcttttg cgatgaatgc
     3061 ttctaatttc tcaaacgttg ctggttcttc ggcatagggc ccgacgtgta agatttgggc
     3121 acaaagacct tcttccatct ttttgaatac tacttgttct ttcaagtctt ccggaagttt
     3181 gctagaacgc tgaatggctt cttgtgctat cgcttctgta acaaagtcag gctgtcggat
     3241 catcaattga taagaaaaat gttctttttt catcactggt tcatgcaaat acttttcttg
     3301 cagtccccat tgtccttcca gtggatagac agtatacatc tgataatcag gaatcagcca
     3361 atttttttta ggcgacatgc gtattgcata gctgactgca tatagacagg ctactcttcg
     3421 tttaaagtct tcctgattcg ggtcgccgat ccctctgatg ctaaagaatg attttttagg
     3481 aacctctagt atttgcgggc tttttttcat actatagctc ttatctttac gccattcaat
     3541 tttttccatt tttcttcctc cgcgaaattc catttagtta tttattatca tacctctttt
     3601 tgagtgactt ggctaatcgt gttgacacta tttttcagtt tgtgctagaa taagtgaagt
     3661 aaataaatcg tacagataac acgtttcggc gtgtcgagag agaggcggtt tctattttta
     3721 taatagaaat cactctcttt ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca
     3781 aaaacagctg cttttagtac ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt
     3841 attgatcgag acggccatga atgtaacttt cccaactctt atcagacagt ttgatttaac
     3901 gactgcacaa gtccaatggg taacaacgat ttatcttttg atgatttcga tcattgttcc
     3961 gctgtctact tatttgaatc gcaattttag tctcaaaaaa ctctttttag cttcaaatct
     4021 gcttttcttg gcaggtataa tgatcgattt cttctctcct accttcatgg tcctattgtt
     4081 tggtcgattg ctccaaggtg cagcgacagg tatcgctctt ccgttgatgt tccatattat
     4141 cttgacattt gcccccctca atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac
     4201 ggccattgct ccagcaattg gccccactta tggaggcatt atgacttcac attttacatg
     4261 gaatcatatc ttcctgtttc ttgtgcccgt tttgtttctt tctttgatta tcggctggtt
     4321 tgctattccc gagatggcag tacaaaaaag tggttatttg gattggataa gcgttttagg
     4381 aatttgtctt ttgtttagtg gaagtctaac atttttgagt acgttgggaa cagtttccag
     4441 ctggattgct ttaatcatcg gcggtattgg ctggttcctt ttttactatc gaagtaaaaa
     4501 agtggagcat ccactgatcc gactgtctat tctttcaaat aaaacattcc gcttgttttt
     4561 gattggcttc ttagtttatc agtttttatt acttggtgta tcttttgtct tgccgaattt
     4621 ccttcagatc gttcaaggaa gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc
     4681 agcggttggt gctttgcttt ctcctttttc cgggaaaatg ctggatcaat atggtccgaa
     4741 gaagccaatt tttgctgggc tgattctttc tttgattggt tggctagcat tattcctact
     4801 cataggacac gcttcagtgg gtgtattgat tgcttgtcat gtgttttata tgatcggtat
     4861 cggattatct tacagcaata tgatgaccac cggaatgaat gcactgaatg aagaactaca
     4921 aggagacggg aacgcaatgt tcaatacctt gcagcagttt tctggcgctg tggctacttc
     4981 attagtagcg gtcattatca attacgtcca gcatcatact tcccataact atgaagtgtc
     5041 tactacatta ggatcaaaag cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt
     5101 tgctcgattc gcctattatc tgttctttgc taaaaaagcg tagattccat atacggcagg
     5161 tgttgcatct gccgtttttt tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg
     5221 gaaaaaattg ccattatcgg tggcgggatc attggtatga ccctagccag ttacttagat
     5281 acatcaaaat tcaatgttgc tttatttgat gaagggacag gacaggcaac taaagctagc
     5341 gctgggatta tctccccttg gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct
     5401 aaagacggcg ctgctttttt ccctaaactt ataaaagatt tccaacttga tcaaacgatt
     5461 tacgcacaat cagggacact tttgcttcga cctgaaaaag atttagctga attggctgtt
     5521 cttgccgaga aacgaaaaga agaagcgcca gaaattggaa acatcgaatg gctttcacct
     5581 gaacagacat ctcaagcact tccgttattg aaaccagcag tttcactgcg tatcagtggt
     5641 ggtggtcgtc tggatggaaa agcatattta gaacatcttg gtcagcgttt agcacaaaaa
     5701 caaatggagc agatccaggc aaaagtcact ttgcataaga agagcgattc ttggctcatc
     5761 aagggaccgt ttggagaata cacagctgat cgtgtaattt tgacacctgg cccggcactt
     5821 aagcctttat tacaagaatt aggctatgct gcagatatac gtccgcaaaa agggcagctc
     5881 ttagcatttc agacatctta taagatgagt caagactggc ctgttgctat gcttgacgga
     5941 gaagctgatt tcattccttt catggatgga aagatccttt taggtgctac ccatgaaaac
     6001 gatcaaggct gggatttggc tcctactagc gaagcttata agggattgac taagagtaca
     6061 gaacagttct tgactgatcc agatcagata aaaaactggc catacgagtt ccgtgtaggt
     6121 acccgtgctt atacgtcaga tttttcccca tttttcggcg tactgccaga tgatccaagc
     6181 ttactggctg ctagcggtct aggctcttct ggcttgacca caggtcctta tatcggctat
     6241 ctattagcca acttcttaaa tactggtcat tggcctacgg aagattatca aaaggacatc
     6301 tccacctata ttacgaaaaa tccatcatag aaaaacagct ttttcaagta aggatcccga
     6361 gcgatattgc gcatggatta cttcttgaaa aagctgttat tttagttcaa tttctgaatc
     6421 aaattctcca aactttcttt tgcttcatct ggcaagagat cttttcctat ctgagcttca
     6481 atgaatcgta aacgaatatc aagtcgttgt ttcaccagat ttttatagga cgtatcctca
     6541 aaagaaacag gaaaatctgg tataggtaaa tagtggatgt cttcaaatgg accaaacgac
     6601 ttgaattctg ccgtttgttg cacgattctt tcaacgattg acaatgtcgt ttcaggtttg
     6661 atttttttat catcgaaata tccagtattc aggacatagc aggctgtttg ctgtttcaaa
     6721 aacaactctc gaaaagcttg atagtcttcc ctaagaggat agacacggaa aggattagca
     6781 aatggttcaa tgactagctc atctagctgt ctttttgtag tgatattttc cgcgtctgat
     6841 cgttttgttg ctaatgttgc accaaaagac gctgctaaaa ctgggtcatt gatcttgata
     6901 attggcggaa gcgaatcatc tttcatgatc caaaaaacag catcgatctt ttcgctaaga
     6961 tgatcgactc ggtcgggtgt cgcataacgt gatttgactg tccgcccatt tccgtttcgt
     7021 atatctcctg ttactaggac tttttctcct ttacttgtac atgtcacgcc cacattctga
     7081 caagtaagga aagaagaaat ggccggatca tcagacggat agtcttgtgt tttatcaaag
     7141 taagaaggtt ccaaggcagt agcaaaacca ttttttcgag aaataacgaa agcatcgtca
     7201 tgcaagatcg aaacagagtg accttccgta tgttttgcta aggtaatcgt tgattttcca
     7261 gaaccggaca acccaaatac agccatcgta taggtctggt cattactagc atattgtttc
     7321 atcccaccgt ggcaggcaat aaagccattg cgatttccca atgcccaagc aagcgtcaaa
     7381 gtcgcttttt ttaattctcc aaagtaacgt aatcctagca cagccgctgt attatggaga
     7441 gcatcaaaca aaatgagtcc atttggaaat gtttcatgtg tccattcggg atcacaaaag
     7501 atataaagat ctccctcatc aaaggaaaca gacttttgat aagtctctaa gatcttcgaa
     7561 ttcgctggct gaaaattcag caaataagaa tacaaattgt tctcaaatcc ttctggaatc
     7621 agcaaatgac tttgcacaga aaattcttca gataggccaa cgattacttt tgtatggtaa
     7681 aactggcgct tgcgactttg atacacagct tctcttaaaa ttttctcgta tttgctttgt
     7741 tccttgtcta agtcctcaaa gatccgccga gcacttgctg ttcttcccac aatgcttcca
     7801 tcattgaata ctagtgtcct aacatcagct ggtaaatata gttcttcagc atgtgagatt
     7861 gttaaatctg tgatgatcgt tcctggactc ccttttgcta gttgataagc tgtcttccta
     7921 tcaaaaactt catgaacatt attaccgtaa aatgtcgttt ctacaatcga tcgaatactg
     7981 gataacagtg gatttccact tgtgatttcg tttaattcga gactctcttt tgtactcatg
     8041 gctcctcctc attccctaaa caaaaaaacg ttttctttat tatacattat tcgagttttt
     8101 atttgtactg ctgcgctgtg ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa
     8161 cttgaataaa caagtttctc ggtttcatca ttttcctttt atcggcttag taccagccgt
     8221 ttgctaacca gaatgtttta gcagcatccc atgaaccata acgagatgtt acatattgtt
     8281 ctgctacacg ttcttgattg gcagctgaat agtcgccgtt taagtatgaa gcatctaatt
     8341 gataacggcc gatgtaacgt ccgttagtag ctgtgtatga accgcctgat tctttttgtg
     8401 cgatccattc ttttgcagag cttgaagttg gcgctgttgc agcagctggg gcagcaggag
     8461 ctacttcaac tgtttcaaca ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg
     8521 tagatgctgt attttctgtt gttttgtttt ctgttgttgc tgaagaatca tttgaagttg
     8581 ggattgttaa ttgttcacca acataaatgc ggttgatgtt tgcgatcgaa tttttttcag
     8641 caattgcatc gatcattgag ttgtctcctg caaatttttg tgagatctta gataatgaat
     8701 cacctgattt tactgtataa acttcatcag cgtgagcatt tgtagttcct acaaacattg
     8761 cagtagcacc agcagcaaaa gttgtaccta aaacaatttt cttaaatgaa ttcatattaa
     8821 actccttttt ttctccgttt tttattcttt cgacgctatt aactttatca tttagaaata
     8881 tttcataggt aaaagaaaca tgacatttaa tgacaaaata acgaattatt taatatttgt
     8941 aacatttaaa caaatatttt tttgatacaa aaccataaaa gccttgttgt ataagcaaag
     9001 taatcgtttt tctatgtttt tttatttttg aatgaaaaac gcagattctg taacattcac
     9061 tgcaataatc cataaaaaaa agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa
     9121 aatgtaaaaa atacaaaaaa accagtaatt gttacaacaa ttactggaca aaaactttga
     9181 ataatgttaa ctattttttt attttaactt tctccgcaat aatttctggg catgttccaa
     9241 ttcgtttata acgacttctt ctgtttcttt agctaatatt tcatctaata catcaagcca
     9301 tttttccggt tcttttgttc ctagacgtcc aatagcccaa gctgctgttc ctctgatgac
     9361 agggcggaca tctgttaaac attctgaaat ctcaggcaat gccgttcgat cacctagatt
     9421 agctaaagca atcaatgcgt ttctctgcaa aggtttcttc ccacgccatg aaccagctaa
     9481 atgcccaaat tgctgtttga agtctttatt agacatcgaa agcattggct ttaattttgg
     9541 atatatttcg tctacttttg gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt
     9601 gtaagggcag actaactggc agatatcaca tccataaatg acatttcgca tttttttacg
     9661 atattcttcc ggcatcatcc cttttgtctg agtttgataa gacaaacatc gctgggcatt
     9721 cattcttccg tcaccaagca atgcttttgt cggacaagca gtcacgcagc gcatacagtc
     9781 accgcaacca aattctcctg gtttatcagg ctcaaataca atattagtaa cgatctcacc
     9841 aagatagaca aatgaaccga actcttcagt gatcaacaat ccgtttcgtc caataaatcc
     9901 taaaccagct cgctgtgcta cagcgacatc gatcagttct ccagtatcta cttgcggagc
     9961 tagacgccat tcctcttctt tttgccattt ttctgctctt gtttggatga attcgatcaa
    10021 tcggttcaaa cggtctctga gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa
    10081 ctgcccgcgt ttttcatccc taggcacttc ttcatggatc ccagtaggat acgcaagtgc
    10141 aatggaaatg atcgatttcg gctgatcaaa tgtcatttct ggataaagac gctcatcgat
    10201 atttggatgt tcaaagccag aagtatggcc agctgctttt tgttcttcca acgattcttt
    10261 taatgaatca aaaggttccg ccgtggtgaa cccgattttg tcaattccta atcgtttgct
    10321 ttcttgtatg atttcttctt ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta
    10381 taacccataa tatagttttt cttttttcag ctggacaaac tggatctgct gatcggcaat
    10441 cttcttttct tccatccatt tttttcttgc agcaaatact tcccaataat ttgttgaaat
    10501 taattttctt ttgttatcta atgcattaaa aaaattcaat gaaactggtt ttgtacttaa
    10561 cagttcatgg agccttacct cttcccatgg cgaaaactca gacagatcgc gggaatacaa
    10621 tacttcttca tagagatttt tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg
    10681 cctagcaatt tctactagac gattataaaa catattcatt aatttgctgt tggcaataaa
    10741 ttgactttta taataggccg actggatctt tttgattact ccttctgctt tgatgactga
    10801 aaataatgca ggccatgctt tgacggttat ttcgtcgttt tgtttaacta atacgccagg
    10861 tgtgaagccg actggagaaa ggaacacaaa ataaccgata ccggtatttt catctaaagg
    10921 ctgaaattca tcaaacaacc atttgcctat gtacagctct tcatctggtt ctgttgtctc
    10981 attttgattt gctatgaata atttagctaa ttctgcttca agaaattgaa ggtcttgatc
    11041 cttgtcggta ttttcctgct ggctgatcaa tcgaaagact tcttctttaa tcgtatattt
    11101 atctttacgt gtaaaattca tagccacacc ttccttcctt actctaacta taacggaatt
    11161 tcttcaaaaa aggtatctgt acgacgaaaa acagcataat tttttttcat atctcttata
    11221 aaaaatgcaa ggtctgctcc tcaagctaga ccttgcactt ttcagctttc ttttgtttgt
    11281 gacaaacctt catggatcgt ttcaatattc catttcatca tctgatagta agaatctcct
    11341 tgttctcctt cttttgctat ggaatcagtg aacagtttat catagatttt caaacccgtt
    11401 tcttttgcta cccgttccat gcttcttgag tctacactgg tttccacgaa taaaaccggt
    11461 acttcttttg ctcttatctg atcaatgatc gctttcattt gatcaggcgt accttgactt
    11521 tctgtattga tctcccatat ataagctgct ggcaaatcat atgctcgtga aaaatacttg
    11581 aatgcccctt cacttgttac taataatttt ttgttctctt cgatagaagc aaaactttcc
    11641 ttcgcttgtg tatctaattc ttttagtttt tccacatatg cttctgcatt ttttttatag
    11701 agtgtcgcat tttctgcatc tttttcagag aatatacgtg cgatttcctc cacatatttt
    11761 attccgttag ataggtctag ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta
    11821 gttaaataaa gaggttctac atttttgcta actgcaaaat aatcttttcc ttcttctttt
    11881 ttagccgttt ccatcaagtt atcgaaccag ctgttacctg tttcaagatt caaaccgttg
    11941 tataaaataa catctgcatc gcttgccttt ttgatgtctt ctggtagtac ttcatattca
    12001 tgcggatctg ttccgactgg tacgatactg tggatatcta tttgatctgt tccgacctct
    12061 tttgccatgt ccgccaagat cgaattggta gccacgactg acaacttttc tttacttcct
    12121 tcatccgctt ggtcagaagc ctgctttccg caaccggcta ataccaagaa actaactgcc
    12181 aagattaaaa agagtgattt ttttgttttc atctatctgc ttcctttctg aaataaaatt
    12241 ccttttgttg gagaaaataa aaaagcaagg ataaaaaatg cggtacatgc taacacgatc
    12301 gtagctcctg atggccaatt gtaactataa ctgaaaaaca caccgacaac tgcacttagc
    12361 ataccgattc ctgcagctgt aatgatcatt ttcagtaaat ggttcgttag caagtaagcc
    12421 gtggcggctg gtgtgatcaa catggcaatc accaagattg ttcctactgt ctgtaaactg
    12481 actacagcca ctaatgtcaa aaagaacatc aaaagataat ggatcagcga tgtgttcagc
    12541 ccataagctt ttgccattgt cggatcgaat gatgtgatct tcaattcttt ataaaagaaa
    12601 aagacaaata tcaagacgat tccactaacg agtgctgtca gcaacaaatc gctttcccta
    12661 acagctaaga cattcccaaa taaaatatga tacaaatctg tcgcactctg ggcatatgaa
    12721 atcaagataa tccctaatgc aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt
    12781 ttcaatcggc tccgctgagt cacgaaacca atcactgctg ctgttagcat cccaaaagca
    12841 gtggctccaa agatgtaact aaaaccaaac atataagaaa tggctacacc tggaagaact
    12901 gcgtgagaga tagcgtctcc catcaaagac atccctcgta aaataataaa agaaccgatg
    12961 actccagaag caagtcctac aagcatggaa gtgaccaaag cgtattgcag gaattgataa
    13021 ttcattaatc catcaataaa ggattggatc attttttctc tcctcctttt actaaatgtc
    13081 tgatgatctc accataggcc aattgaaggt tcttcgatgt aaagacttct tgtactggac
    13141 cggaagcgat cagctgttta tttaaaagaa taacctcatc gaaatattct tctactttat
    13201 gaagatcatg atggacgatc aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt
    13261 caaagatctt tcgttcactt aacgcatcaa tccctacgaa tggttcatct aaaaagatcc
    13321 attctgctcc ttgggctaga gctcttgcaa taaaaactct ctgaagctgt ccacccgata
    13381 gttcgctgat ctgtcttttg gcatattctt ccatccctac ttttttcaaa gcttgtcttg
    13441 cacgttcttt ttcttttttc ccaggtcttt gtccaattcg taaagatgga tatgttccta
    13501 aaagtacaac gcctaataca tcaattggaa aggaaagatc caattcactt cgctgttcca
    13561 cgtaggctat ttttttacgg actgagttta ccgactgtcc agaaaaggtg actttaccag
    13621 tagtagctgg tatcaactct agcaaagatt tcataaatgt tgattttcct gcaccgtttg
    13681 gtccgataat accggtaatt ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag
    13741 ttttcccttg ataagcggct gaaaggtctt gaattacaat ggccgtacgt tccaaatctt
    13801 acactccttt ttaggtttac ctaacttttt atttaaatat agtttaacta aaatggaaag
    13861 cattttcaag tagaatgatg aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat
    13921 tttctgtaga atcacatcaa gagttcaata aggctaacct aataatgaaa aacatgtgtt
    13981 gaaacgtttg attatttttt cttgttgact caacaacgaa aggagttttt gtatggaaga
    14041 agaaaagtta actcgaagtc ttagtgcccg tcatatccaa atgatcgcac taggtggaac
    14101 gatcggtgtc ggtctgttta tgggtgcctc ctcaaccata cgttggacag ggccctcagt
    14161 gatgggagcc tatgcgattg caggattctt tttgtatttg attatgcgtg ctttaggcga
    14221 aatgctttac gttgatcctt cgactggttc ttttgcaaat tacgcgagcg agtacatcca
    14281 tcctgtggct ggctacttga ccgcttggag taatattttt caatatattg tcgtaggaat
    14341 aagtgaagtg attgctgtag gatcttatat gaattattgg tggcctgatt tgccggcaat
    14401 tattcccgga atcattgtcg tcttgtttct tatgctggca aatcttattt ctgtcaaggc
    14461 gtttggcgaa ttagaatttt ggttttcgat catcaaagtc ataacgatca ttttgatgat
    14521 cattgcaggt cttggggtaa tcttatttgg atttggtaat catggtcagg cagtagggat
    14581 ttcaaatctt tggaaaaatg gtggattctt cactggaggc gtcaaaggat ttttctttgc
    14641 attatcgatc gttgttgctt cctatcaagg aatcgaactg atcggaatga ctgctggtga
    14701 agcagagaat cctaaaaaga cgatcattga agctgtccag tccactatcg gtcgaatctt
    14761 gattttttat attggtgcta tttttatcat tgtgagtatc tatccgtgga atcaattgag
    14821 tgagattggt tcaccttttg tacaaacttt ttctaaagtc ggcattacat ttgctgcagg
    14881 actgattaat tttgtcgtga ttacagcggc attatcaggt tgcaattcag ggattttcag
    14941 cgcaagtcgt atggtctata cacttgccat aaatggaaag atgtctaaaa aatttctgaa
    15001 actatctcgt cacggtgcgc ctttttatcc tgtcgtagca atctcaggtg gaatcttaat
    15061 tggtctgatc ttaaattatc ttctaccaat gttcatcaac cagtcagaaa atattttcgt
    15121 tttcgtatac agctcaagta ttttgcctgg tatggttcct tgggtagtga ttttgatcag
    15181 cgagattcgc ttcaaaaaga agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc
    15241 actatctcct tatacgaatt atgtgacact tgctttttta gctatcgtat tgattttcat
    15301 gtttatcaat cctgaaacga gaatctcatt gattattgga ctcgttttct tgctttacat
    15361 gacgatccat tactttgtac gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc
    15421 accttagtgg aagcttcgtt cttttttatt gcttttatca attcaatttt agcgtctcac
    15481 cgggagtcag gaaataattc tccatgctca tcccattcag cgacaagatc gtttctactg
    15541 gtacgccagt tcgttcggct atttgatttg gaccttctcc ttccaaaact acggttgtcg
    15601 cagcctgtga agtcgcgctg ttggtattag tttcagagga atctgttgtg tcttgtgttg
    15661 ttcgagcttg catttcagaa gcttctaccg actctgctgt ctcagaatca gaagatgttg
    15721 tgtcttgtgt gcttgttgac tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg
    15781 aaatcttagc gacatgattc gtataattag ccgataattg attgatcaaa gtatctaagt
    15841 ctacaccgtc tttattttct gctgcctgat acgctgcacg taattttctg atcccttcgt
    15901 cggagattgc ttgaagctca cgtgcttttt ggttagcaac tgctgataaa ccagctattc
    15961 cctcttgatt tccctgaatt tctgtctggt attcttcaat caatgcaggc gtcttttctt
    16021 cgatcttttt cgaataatca tttacgattg cttgaagttg ctctggcaaa ccatttgctg
    16081 ttttttcttc agaagtttgt gtctcttttg ttttagttga tgactcactt gtttgtttcg
    16141 tctctgtttt ctttgtcgtt gtttccgtta tggtcgtact tttcgcttct gacgaatttt
    16201 ttccatgaaa atatagaccc gcaactcctc ctgctatgat caaaaacacg gcaactgctg
    16261 ccccaatcat gatcatccgc ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc
    16321 gaacattttc tccccactca ttttcatcat acattttttt caccaccaat ttttatgtat
    16381 aatagcgtta tcaaacgctt catattctta ttgtagcaaa taattgtcgc tgtgcacatt
    16441 tttatctttg ttatttataa gaaaatttca ccagttgaga tgattccaag attgtccgtc
    16501 gatttctcct tgcagctgca ttgttcgttc gtctatctca gccatcagtt tctttatttc
    16561 atataagagc gcacggtctt gatattctga tttttcgctt aattcatcta attgttggat
    16621 cagccaatca tttgtcataa tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct
    16681 tcgatctgct cttttgcctc agtcagtgct tctacgatat atgcttgttt ttcagattct
    16741 tcttcctgca ttttctgatt ttcctgtact ctttgaataa accagtcaat ccgctgagtc
    16801 agcgatggtt tgccttccaa tgagagatac tgctgataag caattagctt ctcccaacgt
    16861 ttttcctggg ataaatacat aaattgtgct aaaacgaatg gcggaagata ggtcatatgg
    16921 aatttatttg cgattcgctg atacggcctc aaaaattcgg aaatcgtata ttcttctttt
    16981 cctccagctt ggtattcttt ttccgccaca cctgttgtca atacgattcc tagttctttc
    17041 ccttttaata catgtgctgc tcgttccaag acattatctt gccaaatttt taaatgagca
    17101 ggagaactat accagtaaaa cggaaactgg aaaatgatcc gatcatgctg ggccaagagc
    17161 tgtagttcag tctctatatc tatttttccg tctggataac ttgattccaa atgatgccaa
    17221 gtagctggta aaccagcaga agcttctttg aaaaattgct gatttaaaga ttcttcgatc
    17281 gttggatggc taatgatgat aagtgtacgc atcccttttc ctccttttta gtcttcgctt
    17341 tacagtgtag cataaccgcc acaagtttct tttgccgatg cttgtcattt taaccagact
    17401 aatcaggttg tccaagaaac tgcggtttgt ttttccaact gttttttcaa ggtatccaaa
    17461 gcaatattct taaaattttc gtttttcata cgtttacgat agttcgtagc cgtttctccg
    17521 gtactctttt tgaacattcg gctaaatacg actagactat tgaaccctac ttgataggca
    17581 atactttcca cggattcatc cgtcagagaa agaagaaacg cccctcgatt gatccgtacc
    17641 ctgatcaaat attccttgat actggtaccc atatgatttt tgaatactcg cgacaaatgg
    17701 ctccgattga ccgctaaatg ctgggcgatt tcctcaacag acaatttttc agcataatgt
    17761 gcctcgatgt atttgactgt ttcaacagct aaagaggaat gaaccttttg tacaccaccg
    17821 ctgacctttc cgccatcttt taaaaggact gataaaaaac ggtaggttaa tgctgttaac
    17881 tgtaattcat tttccaaggt ttcttccgta tctttcatgc attctaaaat aatgtcgata
    17941 tatttttgta tgtcagaaga gaccatcgtg tattggtctt ctctgaaaag cgactgccga
    18001 atgatttctt ctgcagcact cccaccaaat gaaagccagc aatacatcca cggatcttct
    18061 ccatctgata agtaaaacgt cgagtctcct ggacgaatca agaacagatc accttttttc
    18121 aattggaatt gttgattttt cacatgataa gatcctttgc cttccatcac gacatgcagg
    18181 atgtaatcat tgcgaatagc aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca
    18241 caaaaatcaa aatacaattc tttttctact tgttgatgtt ccttttttaa aaaaatcgat
    18301 tgctccacgt ctatccctcc ttactccttt agtataatgc aacaaaaagt taaataaaag
    18361 tcacagaaat atattaaaaa ggaagcgatt tcttgttaag tttaagtcat taaaagatct
    18421 ttgttattcg ttgtaaccgg tttacttagt attatatatt gaacaggaga ggaatacaga
    18481 ttatgaaaag caaaatgatc caacgtgtgt cctacgcttt aggcgctttt ggacacgaca
    18541 cattctatgt tacattaagc acttatttta tggtattcgt gacaagccag atgttcgcag
    18601 gaacagataa ggcaacgaat gcaaaaatga ttgctacagt tacaagctta gttgtaggta
    18661 tccgcttagt tgaaattatt tttgatcctt tgattggtgg catcatcgat aatactcgta
    18721 caaaatacgg taaattcaaa ccatggttag ttatcggcgg cgttgttagt tccgtactct
    18781 tggtagcaat ctttaccaat ttctttggct tagctactca taatacgact ttatttatca
    18841 tattatttgc aatcgttttc atcttattgg atagttttta ttcatttaag gatatcgctt
    18901 tttggtcaat gattccagct ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt
    18961 ttgctcgttt cggctcttct ctaggtgcaa atggtactac tctagtcgtt gtccctatcg
    19021 ttactttctt tacctatctt gttactcata aacatattga aggcgcttca ggctggttct
    19081 ggttcggtgt gattgctgct gttatttcag gcggtactgc gattatcact gccttgggca
    19141 caaaagaagt cgatactgcg atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt
    19201 tcaaagcagt tgctcaaaat gatcagttga tgtggcttgc ccttgcttat atcgcttatg
    19261 cgattgccaa tgtagcaaca actgccgtat tattctactt cttcaaatat gtacttggcc
    19321 aaccaactga attttggatc gttggtctag ttgctgcctt acttggttta gtagctgttc
    19381 cactattccc aatgcttaca cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg
    19441 caatgatgat ttcttcttac tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta
    19501 tcatcgggct agtattgttc tacttccctc aacaattgat tttcttatcc gctttgatga
    19561 cgatcacaga ctctgttgaa tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta
    19621 ctctatcaat tcgcccttta ctagataaaa tcgctggtgc tttgtctaac gggatcgtag
    19681 ggtttgtcgc tatcgcttct gggatgactg gtaatgctac tgctgctgat atcactgctc
    19741 atggcgtaac gactttcaaa gcttatgcat tctatgctcc tgctgctttg atgattttct
    19801 ccgctattat ttttgcttgg aagattacat tgacagagaa aaaacatgca caaatcgttg
    19861 agaaattgga aaacaaattg gctccagctg atacaatgga agatgaactt cacgatgcag
    19921 tagttccttc ccattaagaa aggatcttga aaatgaagat tacagaaaaa gattttggcc
    19981 aaggttatca cttgataacc ttggagaaca aaaacaagct agcactttct atctctgatt
    20041 taggtgctag aatcgtcagt ttaaaatcaa atgatcgaga attagttttg ggatttgaca
    20101 ccgctgaaga atatatcgaa aaagatccgt atatcggtgc ttctatcggt cgcaccgcag
    20161 ggagaatcga aaatggccgc ttttctctca atggaaaaac ttaccaatta gccacagatc
    20221 caaaaactgg acataatctg catggtggtg ctcctggatt tgaattaaaa aaatggtctt
    20281 atgtcatttt gaatggcgaa aatgaagctt ctgtcatttt tactactaca agtcccgacg
    20341 gagaacatgg ttttccaggt acaatggatg tggaaatccg ctatactttg acaaaagata
    20401 atatctggcg agtgacctct cgcggcacca gtgaccaaga tactttattc aatccgacaa
    20461 atcatgttta cttcaacttg acgggagatg cttctcagtc aatcgatcaa catgagcttt
    20521 ggctcaatag cgaagcttat gctcctttgc gaacagatag tattcctata ggggtaaaag
    20581 aaaatgctgc aggaagtgct ttcgattttc aaatacctaa aaaattagcg tccgtttttg
    20641 ctagtgattt ggatcaaaaa aatcttgttg acggaatcga tcatccattt ttcttaaaag
    20701 aaaccggctt gggtaaagaa gccgctcgct tgactagccc cgataaaaga atccaagtag
    20761 atattgctac agatgcttct agtgtggtta ttttcactgc aaatttcggc acagaaacac
    20821 cagaaatgcg caaccgaaaa ctggcacatc acggtggcat cacatttgag actcaaacag
    20881 ctccaggtgc agagcgcttc tcagcatttg gttcgattca tttaaaagcc ggatcagtat
    20941 ttgaaacagt aacagaattc aaaatcaaaa caagaaagga ataactcatc atggaaatca
    21001 aaagaagctt aaacacaaaa tttgccgaaa cattcggacc taaaaaaact acacaatact
    21061 tctcaccagg acgcatcaat ttgattggtg aacacacaga ttacaatgga ggccatgtct
    21121 tccccgcttc catcacttat ggaacgcaag gtgtagcagc acctcgagac gataataaaa
    21181 tattagttta ttccacaaac tttgacgata tcggtgtcat tagttttact ttagatgagc
    21241 tagaatatga taaaaaagca aactgggcaa attacgtaaa aggaatggtc cttaaattaa
    21301 aagaagctgg acactcaatc gatcatgggt ttgagttatt agtggaagga acaatcccta
    21361 atggtgcagg actttccagt agcgcttcat tagaattatt agtaggtgtt gtattagaag
    21421 atctgtttga tttaaaaaca gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa
    21481 atgaattcat cggtgtcaat tcaggtatca tggatcagtt tgccatcggc ttcggtgagc
    21541 tagatcatgc aatcttatta gatacaaata cgctgaaata cgaaatggtt ccagtgaaac
    21601 tagatggtta tgcaatcgtc atcatgaata cgaataagcg gcgggaattg gcagattcaa
    21661 aatacaatga acgccgtagc gaatgcgaag aagccttggc acgtttgcaa aaaactttgc
    21721 ctatctcttc tttaggagac ttagatgaag aagaatttga atcaactatt gaccaaatcg
    21781 gcgatgatac attgatacgc agagctcgcc atgccgtttc tgaaaatcag cggactttga
    21841 aggcaaaagc tgaattagaa gctgggaact tagaagcatt tggtcaactg ttaaatgatt
    21901 ctcaccactc tcttcgctat gattatgaag taactgggat cgaattagat acactagtag
    21961 atgctgctca aaaacaagaa ggtgtcttag gtgcacgaat gacaggagct ggatttggtg
    22021 gctgtgcgat tgctcttgtc aaagaagaaa atatacctgc cttcaaaaac aatgtctatg
    22081 atgaatacat gaaagttgtc ggctatgctc cggaatttta tgttgcacac attggaaatg
    22141 ggacaacaaa gatcgatcca gaagctgttc atgtttgata aaaaaatcaa cgatctcagc
    22201 taaaaacaaa tagataaaaa taacctctca gcaatttcca aatgtgagcc ttttgctcgt
    22261 atttgaaaat tgctgttttt tattgacacg gaaagagaac gtgtgttcta attgtgttga
    22321 agaggtgatt gttatgtggg cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc
    22381 aagagatatt ttatgtattg actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa
    22441 ggatcttgat ccccttacaa ctaaattagt agtcatgtcc tatccgtccg attcgacaga
    22501 aacacggggt agcggattaa tcttggcttc cagtcctgca gcaaaaaaag cttacggcat
    22561 caccaatatc agccgtgcca gagatcttcc cttcccctat ccaagtgatt tatatattgt
    22621 tgccccaagg atggcctatt atatggaaaa gaacagagaa atcaattcta tctataaaaa
    22681 atatgcagac gaagcgaacc atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac
    22741 aaatagcatg gcactctttg gtaaaacaaa tgcgtacgac atggctaaac tgatccataa
    22801 agatgtgttt gagcagaccg gaatctacac gactatagga attggcgata acccgctact
    22861 tgctaaacta gccttagaca atggctcaaa agacggaaag caaatgtttg ctgaatggcg
    22921 ttatgaagat gtaccagaaa agttatggaa aatctcagat atcactgact tttggggaat
    22981 cggcaaacga acagcaaaac gtctgaaaca aatgggtata cattctgttt atgatttagc
    23041 tcacgcggat tattatcact tgaaaagcaa gctaggggtc atcggtactc agctttatgc
    23101 ccatgcttgg ggcatcgatc gaagtttttt gggacaagaa tatacaccaa aatcaaaaag
    23161 tatcggaaat agtcaaatcc tagatagaga ttatacaaga cgagaagaaa tcgagatcgt
    23221 tatcaaagaa atggccgacc aagtcggcac tcgcttgaga cgatctgcag caaaaacaca
    23281 agtagtcagc ttatgggtag gatactcttt aggctatctt gatccaaatg gcaagaccgg
    23341 gtttcaccag caaatgaaaa tcgaagcgac aaatgctagc agagatctag cagatgcttt
    23401 attgaccatt ttccaccagc attaccacta ccaggatatt cggcgtgtag gcgtgaactg
    23461 ttccgacctc gtatacgcga caggtttaca gcttaacctt tttgaagatc ctgaaaagca
    23521 gataaatgaa gcgaaagttg attttgttgt cgatacgatt agaaaaaaat acggctttca
    23581 atcaatcatc catgcgcata gtctcttgca aggaggacgc gccatcgcac gtagttctct
    23641 cgttggcggg catgcaggtg gtatgagtgg attagaaggt ggaaaagatg agacggacag
    23701 caaaaaaatt cattgactat aacgagtatc gagatcggcc atttggatta aaatggggga
    23761 ctgcttttgc gatggaagaa ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa
    23821 acagcctctt cctaaacaac aaatgacatt gcaagaaatc gatagtatac tgacagaagc
    23881 ctttttatct cgtaaagcag taatcattca gctcaattta aaagatgaat ttggaagact
    23941 cttggatgag gtcgaagggc acttcattgg tgaagcctat gaagattact ttatgattga
    24001 ccatcagccg atattgtggg aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg
    24061 gtttgtgaca tgagaggttg tgacagaagt gatcaacttc aaaaaataag aaaggatttt
    24121 tcgaaaattg cttcttaaat ttttgtggaa ttttggctta tttttcgaag aagcaacttc
    24181 tggaacaacg tatattagat atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa
    24241 gccaaggcgc tgatttcaca acctctgtct atctatccat ctattcggta agattcatgc
    24301 atgacgtctt ctttatttag tatgtagagc cctttttctt ctgaccattc aacataaatc
    24361 agctgtttta catctgcata gccttctttc ttcaagttct ccataagcca tgcttcagtc
    24421 aattgattgg actgaagcac tttatgctga atttgccctt catctacaag caggatcgat
    24481 aaagctttgt cttcatctga ttttttcaat acactcattt gaccggcatt ctctaggata
    24541 acatgtttgg cattttcaag aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc
    24601 tccatctcga tatggttatt tgtcaactct gtcatgttga tgacgccgtc tttgattaga
    24661 acagatggct cgcctttgac ccaacgattg accttttcat ttttttggac gatacgttcg
    24721 ataccataaa tcattactgc ccaaagcgca atggcaaata ggacatgccc tacatggaca
    24781 ttgtcatcat aggttgattc ttctaagatc ccacctaaaa caagcgtata gactaaatca
    24841 aacggtgtga tttctgacat ggatttcttc ccaagcaaac gtaccactaa taataaaccg
    24901 atcaacccga acaccagttt cattgtaatt gaaaaaatca ttttttctcc ccctaactat
    24961 ctgttaatta aattatatat gctttctcac gaacacgcat ggaatataca aggaagaaat
    25021 gtatcctttt actaaaaaaa ggactgtgac actgtagtga cccccaaaag ttagactttt
    25081 ttggagtgga gaaatccact cctttttttt atgctctaaa atgatatttt tacacaaccg
    25141 ttacggttgt tttacgaaat tggacg
//
LOCUS       DAIGQM010000045        24579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.045, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000045 DAIGQM010000000
VERSION     DAIGQM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.045"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(153..551)
                     /locus_tag="NOA48_001793"
     CDS             complement(153..551)
                     /locus_tag="NOA48_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCI0790051.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="NOA48_001794"
     CDS             complement(548..1321)
                     /locus_tag="NOA48_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0790052.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="NOA48_001795"
     CDS             complement(1318..2001)
                     /locus_tag="NOA48_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0790053.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="NOA48_001796"
     CDS             complement(2168..3055)
                     /locus_tag="NOA48_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0790054.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="NOA48_001797"
     CDS             complement(3052..3921)
                     /locus_tag="NOA48_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0790055.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="NOA48_001798"
     CDS             complement(4058..5344)
                     /locus_tag="NOA48_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0790056.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="NOA48_001799"
     CDS             5617..6195
                     /locus_tag="NOA48_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0790057.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="NOA48_001800"
     CDS             6195..7124
                     /locus_tag="NOA48_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790058.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="NOA48_001801"
     CDS             7121..8857
                     /locus_tag="NOA48_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0790059.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOA48_001802"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOA48_001802"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCI0790060.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="NOA48_001803"
     CDS             complement(9753..10262)
                     /locus_tag="NOA48_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCI0790061.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOA48_001804"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOA48_001804"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCI0790062.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="NOA48_001805"
     CDS             complement(11563..12654)
                     /locus_tag="NOA48_001805"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCI0790063.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOA48_001806"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOA48_001806"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCI0790064.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOA48_001807"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOA48_001807"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCI0790065.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOA48_001808"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOA48_001808"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCI0790066.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="NOA48_001809"
     CDS             complement(16617..17591)
                     /locus_tag="NOA48_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCI0790067.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="NOA48_001810"
     CDS             complement(17572..19455)
                     /locus_tag="NOA48_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCI0790068.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="NOA48_001811"
     CDS             complement(19473..21698)
                     /locus_tag="NOA48_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0790069.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="NOA48_001812"
     CDS             21813..22847
                     /locus_tag="NOA48_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790070.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="NOA48_001813"
     CDS             complement(22914..23927)
                     /locus_tag="NOA48_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0790071.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="NOA48_001814"
     CDS             complement(24005..24193)
                     /locus_tag="NOA48_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCI0790072.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5342 c         4397 g         7775 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atacaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg ctgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctctct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cgcaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAIGQM010000046        24271 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.046, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000046 DAIGQM010000000
VERSION     DAIGQM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.046"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..572
                     /locus_tag="NOA48_001815"
     CDS             <1..572
                     /locus_tag="NOA48_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0790073.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="NOA48_001816"
     CDS             576..1217
                     /locus_tag="NOA48_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790074.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="NOA48_001817"
     CDS             1214..2131
                     /locus_tag="NOA48_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0790075.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="NOA48_001818"
     CDS             2128..2799
                     /locus_tag="NOA48_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790076.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="NOA48_001819"
     CDS             complement(3340..3828)
                     /locus_tag="NOA48_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCI0790077.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="NOA48_001820"
     CDS             complement(4029..4295)
                     /locus_tag="NOA48_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0790078.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="NOA48_001821"
     CDS             complement(4295..4558)
                     /locus_tag="NOA48_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0790079.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="NOA48_001822"
     CDS             5034..5219
                     /locus_tag="NOA48_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0790080.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="NOA48_001823"
     CDS             complement(5361..7184)
                     /locus_tag="NOA48_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCI0790081.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="NOA48_001824"
     CDS             complement(7782..10487)
                     /locus_tag="NOA48_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCI0790082.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="NOA48_001825"
     CDS             complement(10793..11740)
                     /locus_tag="NOA48_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCI0790083.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="NOA48_001826"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="NOA48_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0790084.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="NOA48_001827"
     CDS             complement(12375..12737)
                     /locus_tag="NOA48_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0790085.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="NOA48_001828"
     CDS             complement(12748..13869)
                     /locus_tag="NOA48_001828"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCI0790086.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="NOA48_001829"
     CDS             complement(13885..14235)
                     /locus_tag="NOA48_001829"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCI0790087.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="NOA48_001830"
     CDS             complement(14365..15876)
                     /locus_tag="NOA48_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0790088.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="NOA48_001831"
     CDS             complement(16198..17550)
                     /locus_tag="NOA48_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCI0790089.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="NOA48_001832"
     CDS             complement(17703..18779)
                     /locus_tag="NOA48_001832"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCI0790090.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="NOA48_001833"
     CDS             18975..20720
                     /locus_tag="NOA48_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCI0790091.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="NOA48_001834"
     CDS             complement(21000..21437)
                     /locus_tag="NOA48_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCI0790092.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="NOA48_001835"
     CDS             complement(21421..22794)
                     /locus_tag="NOA48_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790093.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAICLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="NOA48_001836"
     CDS             complement(23116..23604)
                     /locus_tag="NOA48_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0790094.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="NOA48_001837"
     CDS             complement(23626..24228)
                     /locus_tag="NOA48_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0790095.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6959 a         5162 c         4489 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaataggc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAIGQM010000047        23824 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.047, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000047 DAIGQM010000000
VERSION     DAIGQM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.047"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(53..787)
                     /locus_tag="NOA48_001838"
     CDS             complement(53..787)
                     /locus_tag="NOA48_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0790096.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="NOA48_001839"
     CDS             1114..1524
                     /locus_tag="NOA48_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCI0790097.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="NOA48_001840"
     CDS             1517..2218
                     /locus_tag="NOA48_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCI0790098.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="NOA48_001841"
     CDS             2218..3804
                     /locus_tag="NOA48_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790099.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="NOA48_001842"
     CDS             3823..4044
                     /locus_tag="NOA48_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCI0790100.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="NOA48_001843"
     CDS             4041..4802
                     /locus_tag="NOA48_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCI0790101.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="NOA48_001844"
     CDS             5182..5691
                     /locus_tag="NOA48_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0790102.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="NOA48_001845"
     CDS             complement(5766..6305)
                     /locus_tag="NOA48_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCI0790103.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOA48_001846"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOA48_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCI0790104.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="NOA48_001847"
     CDS             7318..8169
                     /locus_tag="NOA48_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCI0790105.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="NOA48_001848"
     CDS             8197..8832
                     /locus_tag="NOA48_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCI0790106.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="NOA48_001849"
     CDS             8852..9625
                     /locus_tag="NOA48_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0790107.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="NOA48_001850"
     CDS             10033..10830
                     /locus_tag="NOA48_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCI0790108.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="NOA48_001851"
     CDS             10808..11221
                     /locus_tag="NOA48_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0790109.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13847
                     /gene="mutS"
                     /locus_tag="NOA48_001852"
     CDS             11205..13847
                     /gene="mutS"
                     /locus_tag="NOA48_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0790110.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAQGYIDALIEKGYKVAICEQVEDPKTTKGMV
                     KREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDEE
                     AVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVDP
                     LEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKKH
                     GTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSALT
                     KVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPMD
                     HLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQETG
                     IKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILEA
                     EEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELVS
                     DKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLALT
                     VLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPNS
                     LILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNVH
                     VGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGHH
                     TVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIESL
                     KQINLLEMTPMDALNTLYELQKQL"
     gene            13865..15973
                     /gene="mutL"
                     /locus_tag="NOA48_001853"
     CDS             13865..15973
                     /gene="mutL"
                     /locus_tag="NOA48_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCI0790111.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15995..16555
                     /gene="maf"
                     /locus_tag="NOA48_001854"
     CDS             15995..16555
                     /gene="maf"
                     /locus_tag="NOA48_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCI0790112.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOA48_001855"
     CDS             complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOA48_001855"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCI0790113.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18851..19564
                     /gene="treR"
                     /locus_tag="NOA48_001856"
     CDS             18851..19564
                     /gene="treR"
                     /locus_tag="NOA48_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCI0790114.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19641..20087
                     /gene="msrB"
                     /locus_tag="NOA48_001857"
     CDS             19641..20087
                     /gene="msrB"
                     /locus_tag="NOA48_001857"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCI0790115.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20257..20859
                     /gene="ruvA"
                     /locus_tag="NOA48_001858"
     CDS             20257..20859
                     /gene="ruvA"
                     /locus_tag="NOA48_001858"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCI0790116.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20872..21873
                     /gene="ruvB"
                     /locus_tag="NOA48_001859"
     CDS             20872..21873
                     /gene="ruvB"
                     /locus_tag="NOA48_001859"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCI0790117.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21902..22480
                     /locus_tag="NOA48_001860"
     CDS             21902..22480
                     /locus_tag="NOA48_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0790118.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22532..23014
                     /locus_tag="NOA48_001861"
     CDS             22532..23014
                     /locus_tag="NOA48_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCI0790119.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23131..23505
                     /locus_tag="NOA48_001862"
     CDS             23131..23505
                     /locus_tag="NOA48_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790120.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4284 c         5114 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca caaggatata tcgatgcctt gattgaaaaa ggctataaag
    11461 tagcgatttg cgagcaggta gaagatccaa agacgactaa agggatggtc aagcgcgaag
    11521 tgatccagct agtcactcct ggtacagtca tggacagcaa aggattgtcg gcaaaagaca
    11581 acaatttttt aacagctgta gttagtcaag gaaatgaatt tggctttgct tatgccgatt
    11641 taagtacggg agaattgaag acggctcggt tgcatgatga agaagctgtt ttaaatgaag
    11701 cctctgcatt gcagacaaaa gaactcgtat taggcagtga gatcactgat acccttcgtg
    11761 aacagctaag cgggcgttta gggctagtct tttctcaaca aaatgagatg gaagaaaacg
    11821 cggaatttag ctttttgaca agcgaactag tcgatccgct ggaaaaagaa gcaaccggca
    11881 aactattgac ttatttatcg gtgacacaaa agcggagttt agctcatatc caaaaagcag
    11941 tagaatacca accagatcat tttttgaaaa tggattatta ttcaaaattc aacctagaat
    12001 taagccaatc tattcggact gggaaaaagc acggcactct tctatggttg ttagatgaaa
    12061 caaaaacagc aatgggtggc cgtttactaa aacaatggct agaccgtccg cttatccagg
    12121 caaaacaaat taaagcaaga caagaaatgg tcgcttcttt gctagacagc tattttgaac
    12181 gtatcgattt gcagtcagca ttaacgaaag tctatgatct ggaacgccta gcaggtcgag
    12241 tagctttcgg taatgtcaat gggcgagact tgatccagct gaaaacttct ttagaacaag
    12301 tgccaatgat cagagggttg attgaaggaa tcgatcaagg tcaatggcaa agtctgcttt
    12361 cagaaatgca gccgatggac catctcgtcc aattgatcga ccaagctatc caagatgatc
    12421 cgccgttaca aataacggaa ggaaacatca tcaaagatgg attcaatgag cagctcgata
    12481 tgtaccgttc tgctatgaga aacggaaaga aatggttggc agaacttgaa gcaaaagagc
    12541 gtcaagaaac aggaatcaag aacttaaaaa tcggatttaa ccgcgttttc ggttattata
    12601 tagaaattac aaaagcaaat cttggaaatg cagaactgga gaagtatgaa cgaaaacaaa
    12661 ctttagcaaa tgcagagcgt ttcatcacac cagaactaaa agaattggag acacaaatcc
    12721 tcgaagcaga agaaaaatct gttgatttag aatatcagtt gtttttagct gtgagagaag
    12781 aagtcaaaaa ggctatccag ccgctacaag tacttgcaaa agcaatcagt gcagtagatg
    12841 tgctacaaag ttttgcaacg atcagcgaac gctatcagta tgttcggcca gaacttgtca
    12901 gtgacaagca tcagcttctg atcaaagacg gacgacatcc tgtagtagaa aaagtattag
    12961 gacatcagga atatatccct aacagcgtag aaatggcaga agacgaaatg atcttgctga
    13021 ttacaggacc gaatatgtct ggtaaaagta cgtatatgcg acagttggca ttaactgttc
    13081 tgatggcgca aatgggctgt ttcgttccgg caaaacaagc agttttacct atttttgatc
    13141 ggatttttac ccgaattggt gcaagtgacg acttaattgc tggacaaagt acttttatgg
    13201 tagagatgat ggaagccaat caagccctgc gttatgctac gccaaacagt ttgattttgt
    13261 ttgacgaact agggcgagga acagcaacct atgacggaat ggcgttggcc caagcaatca
    13321 tcgaatatat ccatcgtcat gtacaagcaa aaacactctt ttctactcat tatcatgaac
    13381 tgacggtact tgagaaagaa cttccgcagc ttaaaaatgt ccatgttgga gccgttgaaa
    13441 aagacggaga agttgtcttc ttgcataaaa tgatggatgg acctgcggat aaaagctacg
    13501 gcatacatgt ggcaaagatc gcaggattgc cttccaatct actagaacga gcagcagata
    13561 tcctgcatac gctagaaaat ggcgataacg gacaccatac tgttccagct gaagtagaag
    13621 agaaaactaa aacagccaaa caggagcaaa taaaaccacc tgcagaaaaa gtaaatcaag
    13681 accatataca agaccgtgta aaagaagaaa accaacagct ttctttattc agtgaattat
    13741 ccgaaaatga aacagaagtc attgaatcac tgaagcaaat aaatttacta gaaatgacgc
    13801 caatggatgc actaaacaca ttatatgaat tacaaaaaca actgtaggaa gaaggcggat
    13861 atcgatggcc aaaatccaag aattatctga acgtttagct aatcagatcg ctgcgggaga
    13921 agtagtggag cgaccagctt ccgttgtgaa agaattagtg gaaaatgcaa ttgacgccgg
    13981 cagtactcag attgatatct tagttgaaga agcgggactg cggacgatcc aagtgattga
    14041 taacggagaa ggcattttgg cagacgacgt agagaatgcc ttcaagcggc atgcgacaag
    14101 taagatccat aatcgcgacg atctttttcg catacgaacg ctgggctttc gaggggaagc
    14161 tttgccaagt attgcctctg tttctgaaat gactctggaa acggcgaatc aggaagaaaa
    14221 acaaggcacc tatctgtcgc tgaaaggcgg agaagttatt gagcatcgac cagcaccact
    14281 gcgtcaagga acgaagatta ccgtcagcaa tctgtttttc aatacgccag cccgcttgaa
    14341 atacgtgaaa acactgcaca cagaattagc gaacatcggg gacatcgtca atcgactggc
    14401 attgagtcat ccatcgattg cttttcgttt agtacatgat ggaaacaaaa tgctggcaac
    14461 tgctggaaat ggcgatctga aacaaacaat tgcgggaatc tacggattat ctaccgcaaa
    14521 aaaaatgctg aaaatcgaag gaaaagatct agattttgag ttatttggct atgtttcatt
    14581 gcctgaggtg actcgtgcca gtaggaatta cttatcgacg atcatcaatg gacgttttat
    14641 caagaacttt tccttgaata aagcaatcgt tgcaggttat gggtcaaaat taatggtcgg
    14701 tcgtttccct attgctgtat tggaaatcaa aatggacccg cttttagtag atgtaaatgt
    14761 tcatccgacg aagcaggaag tccggctgtc gaaggaaaaa gaactaacag agctaattag
    14821 taacgccatt caaaaagcat tgtctcaaga aaatctgatt ccaagtgcag cggataatct
    14881 acggtttaag aaaaaagtac ctgatcagcc taaaacagaa caaatcgaaa tcgatttgtc
    14941 ctacgctttt gaagaagaaa aacctaaaaa gccaagtagt ttgaattttg atcgagagac
    15001 aggtaccttt ttcgtagaag aactaaagaa cacatttgtt gacagaattg ttgataagtc
    15061 tgtggaaaat gttgaaaact attctggttt ttctgaagaa aacaccactt atccagaaaa
    15121 aacagcgaaa acggtggata agtttggtga aaatgttgat aactttgtag aaaaaacagt
    15181 ggaaaaatct gaaaagaaag aatttcccat tgtggataac atggagaaaa caaatgaaga
    15241 acaagcagat aaatccgtag aagaggatga aaagatttac gaggaagaat tgacactcca
    15301 tcctgaattt gatttcactc aaggaaacga caaaacatta gaacaagcca tcaagaaatt
    15361 agaaacggaa aaaccagtac aacgttttcc tcagttggaa tattttggac agatgcacgg
    15421 aacgtatctt tttgcccaaa gtagcgatgg gttgtacatc attgatcagc atgctgccca
    15481 agagcgcatt aagtatgaat atttccggga aaaaattggg gaagtatctg atgatctgca
    15541 agaattgctt gttccatttg tgttagacta tccaaacagt gatgctttga aattaaaaga
    15601 gcaaaaacac ttgctagaag atgcagggat ttatttagaa gaatttggtc aaaacagctt
    15661 tattgtacgg gcccatccta cttggtatcc caatggagaa gaagaatcga ttattcggga
    15721 gatgatcgat atgctgctga caactggaag tgtgagtgta aaaaaattcc gtgaagcaac
    15781 agcaatcatg atgagttgca aacgatcgat taaagccaac cattatttga atgaagcaca
    15841 agcacgtgtg ctgctgaagg atctggcacg atgcgaaaat cctttcaatt gtccccatgg
    15901 ccgtccagta ttgattcact ttaccaattc ggatatggaa aggatgttca aacgaatcca
    15961 agacccgcat taagtcaaag agaagaggga aaacatgaag attgtattag catcccaatc
    16021 accaagaaga aaagagttat tggctcatat cgtttcagaa ttcgagattg aacctgctga
    16081 tatcgatgaa acgccatttc cagacgaaca gcccgtcgat tatgttcgta gaatggctga
    16141 agaaaaagca cgaactgtct gggaacaaga tgaaaaagaa gaccatttag tgattgccag
    16201 tgacacgact gttgttctca atcaagagat catgggtaaa ccagaagatc tggctgaggc
    16261 tgaattcatg ctgaaaaaac taagcgggga aacacatact gtatatacag ctgttgtttt
    16321 aaaaacaaag gaacgagaag aacggatact agcagaagca catgtcactt tttatccttt
    16381 gacagacgaa gagatcaaac gctacttgga gacgggggat tatgcggata aggcaggggc
    16441 atacggcatc caaaatgctg cgagtgtatt cgtcaaagaa atttctggag attattacag
    16501 tatcgtagga tttccgattg gtgctgtcaa tcaggcactg aaaacattca tttaaacaaa
    16561 aaagcggact atctgatttt cgattgaaaa tccatgatag cccgtttttt ttattgaaaa
    16621 gattacttat ctactctgac taagatttta cttcagcttt accgactgct tcgcccgggc
    16681 gaacaagtcc tgattggtca agagaaagtc ctgcaacttt ttcattattg gtcaaagcaa
    16741 caataatgtc agttttcttg ccagcttgtt ctatttctgg caaatccatt tcagcaatca
    16801 gggtctctgg tgtgacaagg tatccttctt tcacgaatac attgaaagga acacccttta
    16861 gttcaacagt atctaatccc atgtgaacaa gtacttccag cccctcatta gaaagaatac
    16921 caatggcatg ttttgtttca aagacactcg tcactttacc gtttactggt gcatagactt
    16981 tgccgtttga cggttcgaca gcataaccgt cacccatcat tttttgtgag aaaactgggt
    17041 catttacttc agttatttcc ttgatggtcc ctgcagcgac tgcgaataat gtttcttttg
    17101 ttgcaactgc cgtaccagtt gctgaaacag gttcgaaaga ctgtggcgtt gctgttgcgc
    17161 catttgctgt ttgaagttgt acatcagcag cattttcagg aacagcagga tcaatcttat
    17221 tcaaaattcc ctgacgtcta aagatgatcg tcaagccaaa tggaatgatg acagcaatga
    17281 tcattgcgat gatgaaaggt acccatgttt ctgcttggat agctagtatt cctggcaaac
    17341 cgcctactcc gatcgcgtta gctcgaacac ccatcaagtt agcaaacatg ccagctaatc
    17401 cagagccgac cattgcagcg acgaaaggat agacgtattt caaattgatt ccgaacatag
    17461 caggttcagt tacgcctaag taacaagaaa tcattgctgg aatcgagatt tgttcttctt
    17521 ttttattccc acgatgtaag aagatgatgg ctaagactgc agagccttgg gcgatatttg
    17581 ataaagcaat catcggccat aaattcgttg atccgaaatc tgcaatcagc tgcatatcga
    17641 tggcattggt catatggtgg agaccagtaa tcactaaagg agcatacagg aatccgaata
    17701 cggcactaaa caaccagctg atagaagacg tcaatccagt atttacgata tttgagatcc
    17761 agcttccgac tgtccagccg ataggaccta aaataacgtg tgcagctaaa acagttggta
    17821 acaatgaaaa caatggaaca aaaatcatcg agatcgactg agggatatat ttgcggaaga
    17881 agatttctag atacgctaac ataaaccctg ccagcatggc tggaataact tgcgcttgat
    17941 aaccaatcat ctggacttga gcaaaaccaa aatcccaaaa tggaatatct gctgcggctg
    18001 tggaagctac actataagca tttaataatt gcggagaaac taacgtaatt cctaaaacga
    18061 ttcctaatat ttgtgtagta cccatctttt ttgcaatact ccaagtgata cctactggaa
    18121 gaaaatggaa aattgcttca cccggtaacc acaaaaaggc attgacacca ttccaaaact
    18181 tcgagtgttc aacgattgtt ccaccaagac tttcaaactg gataccttca agtacatttc
    18241 tgaatccaag gatcaatcca ccgacaatga ttgcaggaat cagtggtgta aagatttctg
    18301 ctaaaacggc aatagcacgt tgaacgggat gaaggttttg ttttgcagct gcttttcctt
    18361 gttctttgga aaccccttca actccagata ctgcaacgaa gtcgttataa aaagtagaaa
    18421 catcgtttcc tatgatgact tggaactgtc ctgcattcgt gaacatccct tttacgctag
    18481 gtatatcttc gatcgctttt tcgtccgctt ttcctggatc attcaggaca aaacgcatac
    18541 gagtcgcaca atgactaact gcagcaatat tttcttttcc gccgatatca tgtaacagct
    18601 tctcggcatc tgcttgatat tttgccatat caataaaccc ctttctctta acttgtctat
    18661 gcaagttgtt tcttcattta ctatactttt tttcggagag aattgcaagc gttttattaa
    18721 aaagtacgag agaaaatgat atcgttttaa aaagcttaaa ataagctttt cttaaaaata
    18781 ggaacattga aatacaaaaa gagctgtagt atagtgaaga aatgatggaa gaacgagtga
    18841 gggaaaaaac atgaataagt tcaatgaaat ttttttagat ttggaacaga aaattttagc
    18901 gaaagaatat cctccgcatt cgcttttacc cagtgagaac caattgatca aaatttatgg
    18961 tgtttcacga gaaacaatta gaaaagcgct gaatcttttg actacggaag gttatattca
    19021 aaaaaaacaa ggaaaaggtt cgatcgtact ggatcggaat cgcttcgact ttcctatttc
    19081 tggattgact agctataaag agctacagga gacccaacgt attccaagtg aaacgatcat
    19141 ccatacgtta gaagaaacag aagtgacaaa agcattgaac gagatcactg gctgggagat
    19201 cggtgcgcct gtttggcatt tgatacgcga aagaaaaatc aatggcgaag tagttatatt
    19261 agacaccgat tatctattaa aggaaatcgt tcctatttta actccagcac aagcacaagg
    19321 atcgatctat gaatattttg aaaatgagct ttctttgacg attgcttacg cgcaaaagga
    19381 gatcacagta gaagaagtaa cggaaatcat gaaaacagcg atggatcttc acgatgacac
    19441 ttatgcagta gtagtcagaa gcctcgttca tctggaagat acccgctgtt tcgagtattc
    19501 tgagtcggtt caccgattag ataaattccg tttcgttgag tttgcccgac gccgaaaagt
    19561 gtaaatagtt caaaagaaag caaattgttg gcatctgtcc actttggcgc tatgatagga
    19621 tcacaaaggg ggcattttta atggataaac caataagacc agaaaaagaa gaactgaaag
    19681 aaaagttatc acccatggct tatgcagtca cacaagaaaa tgcaacagaa cgaccattta
    19741 gcgggaaata tgatgatttt tacgaaaagg ggatctatgt agatatcgtc agcggtgaac
    19801 cgttattcag ctctgcagaa aaatatgatg caggttgtgg ctggccatca ttcagcaaac
    19861 caataacgaa aagacaagtg cgcgaaaaag ccgatttttc tcatggcatg catcgaatag
    19921 aagttcgaag caaagaagca gattctcatc tcggacatgt gtttaccgat ggaccagtag
    19981 atcaaggtgg tctacgttac tgcatcaatt ctgcctcact gaaattcatt ccatatgaaa
    20041 agatggatga attaggttat ggggaattca aatcacttgt agaataatgg aaatacacaa
    20101 agagcggtac aatacgggga tttactcgat cgtccgctct ttttttattc aagcgattgc
    20161 tatttgaaag aaacgctccc tagactcctt ttttcacaag gtgaaatgtg ctacaataaa
    20221 gggaacgtat gtgtgcaaaa gaaagaggac tagaatatgt atgaatatct gacaggtgtg
    20281 gttaccttta tcaaccccta ttacatagta gtagaaacca atggtatcgg ctaccagatc
    20341 gcactaggaa atccttaccg ctacagtagc aaactaaatc aaaaaataaa aatttatgtc
    20401 catcaggtaa tacgtgaaga tgcgcatctt ctgtatggat ttgattcgct agaagaaaag
    20461 caactgtttt tgcgattagt aagtgtttca ggaatcggtc cgaaaagtgc ccttgcaatc
    20521 atggcaagcg aagaccactc cggtttgatt caagcagtag aatccagtga tgtcacttat
    20581 ttgacgaaat ttccaggagt agggaaaaag acagcacaac aaatgatctt ggatctaaaa
    20641 ggaaaattcg gtgagctgag tatcgataca ccttttagtc tatttgatga agcaaacaca
    20701 aaagacgcta cagctctatc tgaagcaatg gaagctctct cggctcttgg ttacagtgat
    20761 cgagaaatca aacgtgtaga aaaacaatta aaagaagtag ataatcagac aacggatgag
    20821 tatctacgcc aagcactcaa gctaatgatg aaaaaataag gaggagacca aatgacagat
    20881 gaatacttgt tatcaccaga atctggcgaa aatgaactga gtttggaaaa atctcttcga
    20941 ccacagctgc tttctcaata tatcggacag agaaaagtca aacaagaact tcagatttac
    21001 atcgaagctg ccagaaatcg ggaagaacct ttagatcatg ttctgttgta cgggcctcct
    21061 ggattaggaa aaacgacgat ggccatggtc attgctaatg agatgaccgt aaatattcgt
    21121 acgacgagtg gccctgctat cgaacgtccg ggtgacttag tagcaatctt gaatgaactg
    21181 gaagcagggg atgtcctgtt tatcgatgag atccatcgat tacctagagt ggtagaagag
    21241 atgctttatt cagctatgga agatttctat gtagatatca tggtaggaca agggccaacc
    21301 gcacatccgg ttcatttccc tcttcctccc tttactttga ttggcgcgac gacacgggca
    21361 ggtatgcttt ctgcaccttt acgagatcga tttggcatca tttctcatat ggaatattat
    21421 gacgaacagg atctgcagga gatcgtttta cgttcttcgg atatttttca aacagagatc
    21481 attgaagaag gggcattgga aattgctcgc cgatcacgag gaacgcctag aatcgctaat
    21541 cgcttgctca aacgggttcg tgattttgcg caagtccaag gagacgggaa aatcgatcgt
    21601 cctatagcgg atcaggcact tactttgcta caggtcgatc aggctggatt ggattatgtt
    21661 gaccagaaat tgttgcgaac aatgatcgag ttatatggcg gcggaccagt agggttaagt
    21721 acgctttcag taaacatagg agaagagcgt gagacggtag aagatatgta tgaaccgtat
    21781 ctgatccaaa aaggattttt aaagcgtaca cctagagggc gaattgctac tgcttatgcc
    21841 tatgaacatt ttggttacga ctatcatata tgatttttgc ttttagattg gaggaaaatg
    21901 aatgagtgat acaacacgta cgaaacaatt gatcaaaaac gtattgattg atttgtgcca
    21961 aacgcaatct tttcgaaaaa tcagcgtcca aaaaatcgca aacgaagcaa aaatcaatcg
    22021 acaaacattt tattatcatt ttacagataa atacgatttg cttcgttggg tctattgtga
    22081 ggatgcattg cattatttag atccacaatg tctttcactt gataattggg aagagcaagc
    22141 attgaaaatg ctgaaagcaa ttgctgagaa gaaagaattt tatgcaaata ctgtgctttc
    22201 tgacccagaa attttacaaa aagagttttc tcaactgatc caaaaatcat ttatcaagat
    22261 ttttgaacaa atggatgaag aaagacaact ttctgcaaga gacaaactat tttatgctcg
    22321 ttttttttct tacggttgca gtggtgtatt agtcaattgg atcacgaatg aatatgaaga
    22381 aacaccgatg gaaatcgcta tgcagctttt ccgtttagcc aaggatacgg aattatattc
    22441 ttatcgtctt tatgcaaaag aagagttgga agaacagtaa tagaaaaatt ttttgttgga
    22501 aaagcaataa tcgctaaaag gagatgggga aatgacaaaa attttatttg tttgtttggg
    22561 aaatatttgc cgttcaccga tggcagaagg cttgctgaga aaacgaatag cattagaagg
    22621 aagggaagca gaattttttg tggattctgc tgctacaagc acgtatgaag ttggaaagac
    22681 accgcaccct ggaacgaaaa aaatattaaa ccaagaaaaa gtagatatga cgaatatggt
    22741 tgctcggcaa atcacacccc acgattttga aacttttgat tggatcattg gcatggatca
    22801 agaaaatgta gaagaactga aacgaagagc accacgctca gcgcagggga aaatccattt
    22861 gtttttaagt agcattcctg gaaaagaaaa agaaaatgtt cccgacccat actataccaa
    22921 taactttgat gagacatatc acttgatcac agaaggcctg aatcattggt ggaatatttg
    22981 gattgatgaa aataaaataa caaataattt gtaaagttaa cgctttcttt ttaaggcgat
    23041 gttagagcat ttccttgttt ttttgtaaaa tgttaggtaa aataaaatta attaagtaac
    23101 actttcttag ctaaaggagg agtgcattcg atgaacgaag agacagtatc gccaatgaag
    23161 aagcttacga agttagttac tcatacttcg tatcaacttt ttgattcttt tgtaaatgac
    23221 actgaagaac atgctaagaa tgtacgattg caaggaaagt ttattcttga gctgcaaaaa
    23281 gctgctactg aacatagtct agttatctta caagtaagag caaatcgttt gagtagcaag
    23341 tatgaaacga tctcaggctg ggtggcgaca aaaacggtcg aaaaagaccg agtgatgatc
    23401 cgcctacaaa acgaagagca gcagatccgg atggttcctg tagaacaaat tgaaaaaata
    23461 acaatccttt caccagcagg ggaacaggaa cggttatcaa aataatttat accagataga
    23521 aaagcacgta tgagcttgta ccatcaatca ttactaatca aaaataaccg aatgctttaa
    23581 gctgatatca gtaaaacgga acgttttagg atgagtatca tagcatgaca gcattcggtt
    23641 gattagttga atcgattgga tggtacaagt ttttttgata aaaaaaggtc ctgctagccg
    23701 gggagctagc aggataagga gttaaaaatg aaaaagtgtt gttagggttg tttgttggta
    23761 tgcttatata atagtcatta gttgtgaata ttttgtgacg aaagttttcg aaagttgtta
    23821 agtt
//
LOCUS       DAIGQM010000048        23457 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.048, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000048 DAIGQM010000000
VERSION     DAIGQM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.048"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            288..695
                     /locus_tag="NOA48_001863"
     CDS             288..695
                     /locus_tag="NOA48_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790121.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="NOA48_001864"
     CDS             709..1110
                     /locus_tag="NOA48_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790122.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="NOA48_001865"
     CDS             1112..1483
                     /locus_tag="NOA48_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790123.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1856..2056)
                     /locus_tag="NOA48_001866"
     CDS             complement(1856..2056)
                     /locus_tag="NOA48_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0790124.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2361..3593)
                     /locus_tag="NOA48_001867"
     CDS             complement(2361..3593)
                     /locus_tag="NOA48_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCI0790125.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            3847..4416
                     /locus_tag="NOA48_001868"
     CDS             3847..4416
                     /locus_tag="NOA48_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0790126.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4594..5034)
                     /locus_tag="NOA48_001869"
     CDS             complement(4594..5034)
                     /locus_tag="NOA48_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCI0790127.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5192..5956
                     /gene="map"
                     /locus_tag="NOA48_001870"
     CDS             5192..5956
                     /gene="map"
                     /locus_tag="NOA48_001870"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCI0790128.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            5988..6911
                     /locus_tag="NOA48_001871"
     CDS             5988..6911
                     /locus_tag="NOA48_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCI0790129.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            6987..8126
                     /locus_tag="NOA48_001872"
     CDS             6987..8126
                     /locus_tag="NOA48_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCI0790130.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8119..8919
                     /locus_tag="NOA48_001873"
     CDS             8119..8919
                     /locus_tag="NOA48_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0790131.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            8919..9746
                     /locus_tag="NOA48_001874"
     CDS             8919..9746
                     /locus_tag="NOA48_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0790132.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9724..10458
                     /locus_tag="NOA48_001875"
     CDS             9724..10458
                     /locus_tag="NOA48_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0790133.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10558..11424
                     /gene="rfbA"
                     /locus_tag="NOA48_001876"
     CDS             10558..11424
                     /gene="rfbA"
                     /locus_tag="NOA48_001876"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCI0790134.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11438..12010
                     /gene="rfbC"
                     /locus_tag="NOA48_001877"
     CDS             11438..12010
                     /gene="rfbC"
                     /locus_tag="NOA48_001877"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCI0790135.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12032..13060
                     /gene="rfbB"
                     /locus_tag="NOA48_001878"
     CDS             12032..13060
                     /gene="rfbB"
                     /locus_tag="NOA48_001878"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCI0790136.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13158..14009
                     /gene="rfbD"
                     /locus_tag="NOA48_001879"
     CDS             13158..14009
                     /gene="rfbD"
                     /locus_tag="NOA48_001879"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCI0790137.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14044..16077
                     /locus_tag="NOA48_001880"
     CDS             14044..16077
                     /locus_tag="NOA48_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790138.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16121..17401
                     /locus_tag="NOA48_001881"
     CDS             16121..17401
                     /locus_tag="NOA48_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCI0790139.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17611..18417
                     /locus_tag="NOA48_001882"
     CDS             17611..18417
                     /locus_tag="NOA48_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790140.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18429..19649
                     /locus_tag="NOA48_001883"
     CDS             18429..19649
                     /locus_tag="NOA48_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790141.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19639..21225
                     /locus_tag="NOA48_001884"
     CDS             19639..21225
                     /locus_tag="NOA48_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0790142.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21264..23402
                     /locus_tag="NOA48_001885"
     CDS             21264..23402
                     /locus_tag="NOA48_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0790143.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7491 a         3909 c         4818 g         7239 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttata cctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgcttcgtgc gtctggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca tccttcttca ttctagtttt cgcagcagga attttaatat actgaataat
     1681 agaaaacaag tacttgtgcc aaattatgtg ccaaaaaaat tcgaattcaa caaaatgtaa
     1741 acaaatagaa aaccttctat attaagattt cctgcaataa caaacacaac agaagacgtg
     1801 taatagttag tcaggaacgt acaaataacc cctgtatcct ttgcggtaca gggggttatt
     1861 ttgtataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa
     1921 gtatatttac tccttgataa agtaaaatag atgcatgcgt atgtcttagt ccatcaataa
     1981 acagtcgaag agaaaatagg gaaaaattga ttactaaaga aaaacttact aggtcgacgg
     2041 tgtagttgat tttcatactt caatagattc gaattaaacg atttcgattg gcttatacca
     2101 gtcctatcca acgaaagata tatcgttctt aactctagcg gtataacttg aagctttacg
     2161 taaagccaat gggaatgaac tggagatgac tttttattat ttttagtaat agctgatggg
     2221 ttaatactta caactttcct tttcaaagta ccatataaaa aaacggtggg gttgtttagc
     2281 gaaataaagg atctaagcca atagcttaga tcctttattc tatgctttat attatttttt
     2341 gcatgtgtgc gaaagtatac tcaagcccaa tcgccatttc ggaaaatcgg tactgtagag
     2401 ccatcttcac ggattccgtc gatatccatc ttgtcagatc ctaccatgaa atctacgtgg
     2461 gtttgacttc tattcaatcc agcttctgct aattcttcat cggacatttc tgtaccgcct
     2521 ttcacactga aggcataagc agaacctagt gctaagtgat tcgatgcgtt ttcatcaaat
     2581 aatgtattga aaaagatgat gccagattga gaaataggtg aagggtcagg tacaagtgcg
     2641 acttctccta aacgacgcgc accttcatct gtatcaagca gttttgctaa gacatcttct
     2701 ccttgttcgg cagaaaaatc aacaactttt ccatctttaa aagtaaattt catacccgag
     2761 atgatggtgc cagcataact cagtggcttt gtacttgaaa tgtaaccatc tactcgatga
     2821 ctgtcaggtg ctgtgaacac ttcttccgtc ggcatatttg ccatgaattt ttctccacga
     2881 gcattatagc ttccagcgcc ttcccaaaga tggtttttag gcaatccgat aatgatatct
     2941 gtaccgggag cagtatagtg aagggcagaa aattgttctc gattcaattc ttctgctttt
     3001 tttgctaatt tttcatcatg cttcttccat gctaagacag ggtcttcttc atagacacga
     3061 gtcgttttga aaatctgatc ccataatgcc tcaacttgtt tttcttctgg cagttctggg
     3121 aagacttttg ctgcccattg tttaccagcc gcagccacga cagtccaact gactttattt
     3181 gcttgagttg ccttgcgtaa attcattagt gctttgccat tcgctgattg ataagacgct
     3241 actcgatggc tatctacacc agcaaatgca tcgggatcgg cagaaacaac gctgatcctg
     3301 cttgctcctt tttcaagcca ttcatccgct tgatcgattt tagattgtgg tacattctca
     3361 atacgatccg ttgcagcatg taaaagaaat tctctttgga tctggtcgtc agtccattga
     3421 acgataacct cagcggctcc tagtttataa gcttcttgtg tgatcaatcg agcaaggggt
     3481 gcctgttcca cgctgatctg taaaacaact gtgtgtcctt tttctgtggc tacgccagtt
     3541 tctgcaatta agcgtgcata tttttttaga agttcattaa aatcagataa cataataaaa
     3601 attcctcctc accatttttt ctggtaacta ttagcatgat accatttaat tatgattcaa
     3661 acaatgaggc tttaaataaa aaaaggaggt tattttttta aggttaagtt tcatgatata
     3721 tgttactact tgctatttca gcttgtgaag aaaatcaaaa actaattttg catatcaaaa
     3781 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     3841 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     3901 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     3961 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     4021 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     4081 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     4141 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     4201 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     4261 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     4321 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     4381 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     4441 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     4501 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     4561 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     4621 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     4681 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     4741 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     4801 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     4861 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     4921 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     4981 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     5041 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     5101 ataaaaccta aagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     5161 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     5221 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     5281 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     5341 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     5401 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     5461 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     5521 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     5581 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     5641 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     5701 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     5761 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     5821 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     5881 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     5941 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     6001 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     6061 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     6121 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     6181 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     6241 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     6301 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     6361 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     6421 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     6481 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     6541 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     6601 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     6661 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     6721 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     6781 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     6841 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     6901 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     6961 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     7021 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     7081 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     7141 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     7201 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     7261 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     7321 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     7381 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     7441 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     7501 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     7561 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     7621 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     7681 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     7741 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     7801 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     7861 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     7921 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     7981 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     8041 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     8101 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     8161 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     8221 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     8281 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     8341 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     8401 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     8461 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     8521 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     8581 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     8641 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     8701 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     8761 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     8821 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     8881 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     8941 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     9001 cacttagcga aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     9061 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     9121 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     9181 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     9241 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     9301 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     9361 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     9421 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     9481 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     9541 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     9601 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     9661 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     9721 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     9781 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     9841 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     9901 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     9961 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
    10021 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
    10081 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
    10141 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
    10201 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
    10261 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
    10321 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
    10381 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
    10441 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
    10501 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
    10561 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
    10621 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
    10681 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
    10741 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
    10801 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
    10861 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
    10921 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
    10981 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
    11041 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
    11101 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
    11161 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
    11221 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
    11281 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
    11341 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
    11401 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
    11461 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
    11521 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
    11581 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
    11641 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
    11701 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
    11761 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
    11821 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
    11881 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
    11941 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
    12001 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
    12061 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    12121 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggccg gacttcctag
    12181 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    12241 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    12301 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    12361 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    12421 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    12481 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    12541 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    12601 tccttatcag catattgaaa aatttattcc tcgccaagta acgagtatct taagcggtat
    12661 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    12721 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    12781 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggcca
    12841 accaaaagac gcatacgacc atgtaaacga ccgcgcaggg cacgatttgc gttatgcaat
    12901 cgattcgaca aaattgcgag aagagctagg ttggcagcct gagtttacga acttccgtga
    12961 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    13021 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagaggaa atttcactgt
    13081 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    13141 aaggagcgga taaccatatg tttttattaa ctggaggaaa tggacaatta ggtacagaat
    13201 tgcgccattt attagatgaa aaaaatctgc catatgtttc aacagatgca aaagacttgg
    13261 atatcacaga tgctgagaaa acaatggctt atattacaga attaaaaccc gatgttattt
    13321 tccattgcgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    13381 agaaaatcaa tgtcgatggc acaagaaatg tagcacttgc agcaaaagct gtgaatgcac
    13441 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    13501 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    13561 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    13621 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    13681 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    13741 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    13801 gttcttggta tgagttcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    13861 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    13921 aaaagacaga agcgttaggt tttgtcatac caacttggca agaagcactt gcgcaaatgc
    13981 tggaagctgc caaaaaaatg aataagtaat ttccttttta tcaaatagaa tttggagcat
    14041 gatatggaaa aacaaacaag aagtgcacga cgaaaagaaa agccaaaagc gaatcaggca
    14101 gattcgaatt tggtgcttga cctgtttcta aaactccgct atcttattgg cgttttagtc
    14161 atcgtggtca tcgttacttt taatttaaac ggaagttcac ttggtgtttg ggataaatat
    14221 gtgtcgcaaa gagacgatgg gaaaaaaact gatgtgattt ttggacagaa tcgggaagtg
    14281 cggtcagacg aatggctggt gcagacacct ttttacctct cacaagctga agaggacttt
    14341 tcgttggtga acgaggatta ttcattaaac ggacaaaaca tgatcattgc gtataattct
    14401 cctgtaaagg atattacggt tatcggaaaa ccattcaact ggggattctt tttcctcgga
    14461 agagatcgag gactttcctt ttattgggcg atgaaattag tcgtcatggt cttgcttgga
    14521 ttcgaagtac tgatgatatt aacgaagagg aaaaaagctc tatcgctaat cggtgcattt
    14581 gcgctgacat tttctccagc agtccagtgg tggttcatgc aacatgtggg cgatttgatt
    14641 ttctttactt tgggactgat gattgctttt tatcattatt tctacaatca tgataaaaaa
    14701 tggctacgaa cgttgatgat gcttttggtg gttattttcg gtattgggtt tattttagtg
    14761 atttacccag cccatcaagt gatgctggcg tacttgctga ttttttattt tgttggcctg
    14821 cttatttact atagcaagaa agtttcatgg gatctgttgg atgtagtgtt gattggaggg
    14881 gcagttttat ttattggcgg agtcatggtt catttctggc taacgtcaaa agacgcattg
    14941 ttagcttctt tgaatacctt atatccagga aaacgggtaa gtactggagg aaagtggacg
    15001 attggcgaat ttttttcttt ccttacaaat tggaaaattc cttttgaaga tatcaactat
    15061 tcgaataact ctgaagtggc cctgttctat cacttttttc caactgtatt cctagcaagt
    15121 ccatttgtgt tatttggcaa aaaagatagc gaacaaaagt tactgggacg tattttgatg
    15181 attttttgtc tgttttctat cttttggatt accgttgggt tgccaaaatg gctagcagaa
    15241 atcactctgc tgtcttatgt tcctccatta agagccatcc ttacttttag ttttgcggct
    15301 tgtttattat cgatctggtt tatcgcttat atttggagag aagatgttat tcctatttgg
    15361 tataaattca ttttgttggc agtaaatgca tggtcttatt tctatgcgat tacgcattcg
    15421 aaaatggata attatttttc ggattttgaa accatcgcag ttgctgtgtt gggaacagtg
    15481 attttagctt ttgcattatt tggctggaga cgcttgtttt acctcgcttt tgtcgcctta
    15541 gttatcgtat ctggcttttt cgtcaatcca gtcgtagaag gtacaggagc gatttttgaa
    15601 aaaacactgg caaaagaaat ccaaaaaatc gatcaacaag atcctggtaa agtttggttg
    15661 tctgaagatg aattatataa cttcacccca acattgggag tgaaatcctt caatacagta
    15721 cgcttttatc cagatatagc tgcatggaag aaaatcgatc cgaaagaaga atacgagaag
    15781 tattataatc ggtatgctca tacaagagct tttatcgcta aggaagatac aaagttcatt
    15841 ttagatcgtc cagatatgtt ttcggtcacg ttgaattttg aagacgcaga aaaattaggg
    15901 atcgactatg tgatcagtaa acgaccatta actgattaca accaattata tgaagcgcag
    15961 ttcacgcagc tatatggacc ggataaagac ggttatatga tttttaaagt agaatatccg
    16021 gattatccag atgtaccaca aacacaaact caggaaaatc agctagtcgt acagtaatag
    16081 gctagctgag aataatcctg aaatattagt agaaaggaga gtgaagataa ttcaagcaat
    16141 cgtacaaaaa tttgtcaaca aaatgagtgt cggtttcttg cttttgttgc tgacgctagt
    16201 cttttttgtt tggacagcag gggtaggttt tccagcaact ttgtttatat ataacaatag
    16261 ttcattactt atcgctttta gtgtggctat tttgctcatt ttaaatgttt ataaagcaaa
    16321 aggcgtcgat tttctttatc taggtgttgc gcttgccctt ttcattttct tttcttactt
    16381 tcgggaatta agaaatgagt ctttatttgg agacttactg tttcctttga ttattttatt
    16441 ttgtttagta attaaatgga tcgagtggac aaaatgggat cgcggtattt atctgattgt
    16501 ctttacggtc ttcctcggaa tcacgttata tcgtgtattt acagagatcc aagtaccaga
    16561 aggacaaagc atctgggctc caggcaattc gctttctgat atttggatca atacgaatac
    16621 aatcggaagt tctttgatga ctcttgcttt attgatcagt ggatttgcca gttcttttga
    16681 acgatggtat gttcgaatca tcggtgggat agcagtcgtt gcagcctttt taggtatttg
    16741 ggtctgccaa tctagaggtg cattagtcgc gttgattgtt tttgcgatat tggatctttt
    16801 acctaaatcg ttgatgcgtg tcattcgtgc gccatttatt gcctacacgg ttacgattct
    16861 tttagctttg ccgatttctt atctggcggc tgtctctgaa aaagtcaatt tgtttaccgg
    16921 tcgagaagat atttggcata aattctatca gacgctagga gaaaaatctg aacaagtttt
    16981 actaggaatg aaaacattta tcttccagcg aggaaaccaa tttttaggaa accacaatag
    17041 ttataattct attttgaata tctatggatt gataggattt gggattgctg ctttgctgct
    17101 tatccttttt attggtcgct taacgttgaa agcagattta tccaacgggc agatgacttt
    17161 tatctgggcc ttttttgcgg tgatgatgca gtcatttatg gaggatacat tgacttcata
    17221 cccatgggtt ccgattattt atatcctgtt ggctatggcc gttcatcgat atgatgaacc
    17281 agaagttacg gaggaattct atgttatgga agaggcatat gacgatatga cttatgatga
    17341 tacatcttat gaggaacaac cagatagcgc tcattcttcc aggatccaac gctatcattg
    17401 ataggcacaa aatacgagag aggctgtgac aaccgtcgca gccttttttg gtttattgca
    17461 attgtctagc atcttctgta aaatagaaac gttagagaaa atcttgtatc atagaaaatt
    17521 aagaaagaaa taagaacgca gctcggtacc aaaaatatgg taaaatggca cttgactgta
    17581 attcactgaa aatcgcttgg aggaacacaa atgtttaaag atttgtattt atttatgaag
    17641 gacatttatc agaacagaaa attactgcta cagttttcga tcaatgactt caaatcaaga
    17701 tatgcaggat cgtttttagg aatcttatgg gcgtttatca atccgctatt tactgtattg
    17761 atttattggc tggtatttgg tgttggactg aaagcacaaa tgatcgatgc aaaataccca
    17821 tttatcgtat atttagttac cgggatgatt ccctggttct tcttctcaga tgcatttgca
    17881 tcaactacgg ttgtttttcg ggaatatact tatttagtaa agaaagtcgt attcaatatt
    17941 cgtatcttgc ccacgacgaa aatcctatcc aatctgtaca cccatttatt cttcattctg
    18001 attggcatag ctgtcgcgct tataaatggt atatatcctt cagcaatgtc tttacagctg
    18061 atttattatt tattttgcat gtgtgctttc ttgacaggat tgacttggct gacggcatcg
    18121 atccaaccat ttttacctga tatcatgcaa ttaattacga tcgtgctgca gttgatcatg
    18181 tggacattac cgatattatg gagccctaat cagtttgatt caggtcttgt aagcatattg
    18241 aaattaaatc cgctgtacta tgttgttcaa ggttatcgtg agtcattttt aagtgaagct
    18301 tggttctggg agcatggaac atatactttg tatttctggg ttttcacgtt agtaatgttc
    18361 gtaatcggct ctgcagtgtt ccgtagattg aaaccacatt tttcagatgt gctgtaagga
    18421 gaatagctat gacagaatat gcaattagac taaaagatat cacaaaatct tataatatgt
    18481 acgcaaaacc ttcggatcga tttcgtgaag ccctcaatcc ttttaagaaa tcctatcatg
    18541 atgtatttta tgcgttgaaa aacgtgaatg tagaaataaa aaaaggtgag atgatcggtt
    18601 tcgtgggaga aaacggatcg ggaaaatcta caatgttgaa aatcattacg ggagtactga
    18661 caccaacatc cggcacgatg gaaatcgaag gaaaaatctc agctttgcta gaactaggat
    18721 caggattcaa tcctgagtat tctggctatg aaaatatcta tttaaatgga atggttctag
    18781 gattttcaag agaagaagtc gatgaaatgg tcgatgatat cattgaattt gctgacatcg
    18841 gcgaccatat ttatcaacct gtaaaaacct attcaagtgg gatgttcgtt cgtctagctt
    18901 ttgctgtagc gatcaatgtg aatcctgata ttttgattgt ggatgaagca ttggcagtag
    18961 gagatcttga atttcaacta aaatgtatgg aaaaatttac agaaatcaag aactcgggaa
    19021 agacgatttt attcgtttct catgatatta gttcgattcg ccgtttttgt gatcgttcct
    19081 attggttgaa aaatggaaaa gttgtcgaat atggtgatac gatggaagta acgacgaatt
    19141 acgaaaactt tttgaagaaa aaatcagtta aaacagtaga tcgaaataaa aaccaagtag
    19201 aacgcttcgc agctccagat atcgtagacg tgacgaaagc cgaattgttg gataaagata
    19261 aaaatccagt ggatatgctg gaacaaggag aaaaactata cgttaaagta acctatgaag
    19321 taaaagacga tacaatcaaa aatccagttt taggaattgc tctgcgtaca gtcgacaatt
    19381 tttatgtgtg cggactcaat actctactag atggtatcaa gatcccttgg aaaaaaggtg
    19441 agaatatctt ttatctggag tatgaaaagt taggtttgtt agctggtgaa tattattttg
    19501 acgttgcggt ctttgaagaa aatgcaacgg ttcctttggt atacaagaca aaatacatga
    19561 acttgtttgt cagcggttct tatatcggag aaggcatcgt ggtcttagac cataaatggg
    19621 aagaagggac tcatagcaat gaaatatgat tttgaaatgg acctagatga acaaagcagt
    19681 gtgggaaaaa ttgccgcaca gatcaaacca ggaagtaaag ttttagagtt tggtcctgga
    19741 aacggccgat taacgaaaca tttgatcgga gcaaaacaat gtgaagtgag cattgtcgag
    19801 ctagataagg aattgttcga ttttgtcagc gagtttgccc aagatggatt ttatggagat
    19861 atcgaaagtt ttgaatgggc aaactattat gctggacaaa catttgatta cgttttgttt
    19921 gccgatgttt tagaacattt ggtagatcct ggaaaaacgt tgaagaaagt tagagaattt
    19981 ttgaatgaag aaggagaaat tctaattaca ttccctaacc ttgcgcataa ttctgtcatg
    20041 attgatttgt tcaataatca attgccatgg gcttcttatg gtttgctaga tgaaacccat
    20101 aattcttttt atactcatga tggcttccaa aaagtttttg aaaaagcagg attatacatc
    20161 aatattgaag attatttgta cttagctgta ggtgatacag aattaaaatc aacttatgaa
    20221 gaattgccgg aagctgtacg ttatgatttc aaaatgcgac catttggcga agtctaccaa
    20281 tacttcttct cattgatgaa acatccagta gcacaaagtt ccattgcgca gccgcaaaat
    20341 tctaattatg tgaaagtatt agaagtaatc cagcaaacga aacaagatga aataattcaa
    20401 caaataccat tcaataattt cacaggggaa aatgagacac taagtttcca tgtatcagaa
    20461 ttagcagaac gaatggtgtt tcgcttcgcg cagcaaccta gctttatcga attcagcgca
    20521 gaagctgctg gagaaaaact cacatttatc gattcaaatg ctgtagtcaa aacagtaaat
    20581 gattgttatt tgtttgatgg taaagattta ccagagttct ttttaacgga tattgcaggg
    20641 aaagaagtga ctatccattg tcactatcgt tttatcggag aattgacacc aacaatgaaa
    20701 gaattgctgg aaacaatccg tccaatggct gaagttacaa agcagctttc tgagaaaaat
    20761 gatgaattag aaagagaaaa tcattatctt attgagaata atacaagatt agatcagacg
    20821 ttgaaaacaa ccataaatcg ctattgcacg ttgttggaaa gtgatgaatg gacaatcaaa
    20881 catagattag ggcgacgtaa gaaagaaaca tcgaaaaaaa tccaagaaaa agagctttct
    20941 ctatgtattg acgaaaaaat ctgggatgca gaaacaaaga tattgaaaat catcgggtgg
    21001 ggaatcgcta attcggatcg ccaaccattg tcctataagt tatcagccga ccaatcacca
    21061 ttttttgaag caattcctgt tttacgagaa gaagtcaatc aagcaaaaca gctagctgaa
    21121 ggagcaaaag caggatttga actgcggatc ctttgcgaga aggaacgttc attcttagtt
    21181 gaagcagtgg ctcaaaatgg tcaatcatgg atcattgaaa tgtaaataat gattaactta
    21241 taaagataag gagtaaacga atcgtgcaaa aaaaagaaat tgccgtattt atcgatcaaa
    21301 tcactcgtga acgggccact ggcgatttgc ttattgtggg ctgggcaatt gatgaagtga
    21361 ccaaagaaat ccctacgata aaggtagaaa aagaaaatgt gattgctgaa gcaacacatg
    21421 tcgtaagatt ggatatcaat catttatata atcttgatgt taagacccaa agcggtttta
    21481 aggtacgttt atcagggaaa atgagaggaa aagcaatctt agacttccaa acagcaagac
    21541 atcaaaatgg catagctgtg aaattaaacg gtaaatatcc ttatgatgac ggcattgaat
    21601 cttcatggga aagaaaaaaa agattactga aaaaagggat aaattatgca aggactcatg
    21661 gcgtaaaaaa agcaatccgc cgggtcaaac tggaattgaa accaggatcg atcgactatg
    21721 cagagtggat cagtcgtcat gagaaacctg atctgaaaga gcaaaggaaa gaagtacaag
    21781 gatttgccta ccgcccattg atttccatac ttatgcctgt ctataacgtt gaaatcaaat
    21841 ggctcgaaaa atgcattgat tcggtacttg atcaaacgta tgatcactgg gaactatgta
    21901 tcagtgatga tgcttctact gatccagcta tccgaaagtg tctagaatcc tatcaagcaa
    21961 aagatgatag aattaaagtc gttttccgac aagaaaatgg acacatcagt ctggcaacta
    22021 attctgcatt gaaaatggca gaaggagagt ttatagcgct cttagataat gatgacgaat
    22081 tacctccatt tgccttatat gaagtggcaa aagtgctaaa cgtacatcca gaactggatt
    22141 tgatctacag tgacgaagat aaaatcgatg cagatgggaa tcgctttgac ccgcacttca
    22201 aagcagactg gtctcccgat acattgatgg gaaataatta tatctctcac ttaggcgtat
    22261 atcggacaag cattgttaag gaacttggcg gtttccgtaa aggatatgaa ggctctcaag
    22321 attatgattt ggttcttcgt gtgacagaac aaattcctgc agaacacatt taccacattg
    22381 accgtgtctt gtatcattgg cggacgatcc cgggatcaac tgcaagcaat ggagaagcta
    22441 aaagctacat ctatgattct ggagtgaaag cattgacaga tgctctatct agaagaaata
    22501 tcaagggaag cgtacatcct ggcagaattt ctggttttta tgaaatcact tatgatgttt
    22561 tgcaagaaga cttggtcagt gtgatcattc caactaagaa tggctatgaa gatctaaaaa
    22621 cttgtgtgga ttcgatcatc gaaaaaacgt cttatccaaa ttatgaaatc attattgcag
    22681 ataatggaag tacagatcct aaaatgcaag aattatttgc agaatacaag catcagctga
    22741 aagaccgatt tatcgtcgaa ttaattgaca ttccattcaa ttattcacgt atcaacaatc
    22801 tggcagcaga aaaagcaaac ggcaaatact ttttattctt gaataacgat acagaagtga
    22861 ttgaacctga ctggatgaca gcgatggttt cttatgcaca gtttgatcga atcggctgtg
    22921 taggagcaaa attattttat ccggatgata caacgcagca tgcaggtgta ttattaggga
    22981 tcggtggcgt tgcaggacat gcattgaata actatgatcg aacacattgt ggttactttg
    23041 gccgattggt cattgacgtc aattacttag cagtcactgc agcttgtatg atggtcaagg
    23101 cagctgactt caatgctgtc aatggatttg atgaaatatt agaagtagca ttcaacgatg
    23161 ttgacttgtg cttgaaagtt tatgaactgg gtcgttacaa tgtctatgca catcaagcag
    23221 aattgtacca tttcgaatct aaatcaagag gttatgaaga tacaccagaa aaacaaagac
    23281 gttttgctgg ggaaatcaaa aaaatgcaag ataagtggcc ttcttatatt gctcatgacc
    23341 cattttataa cgataatcta actaaagaag gaatcggcga tttttcgttg agacctgatt
    23401 gattaaaaga actgtatttt catttttatt aatgaaaata cagttctttt aatttaa
//
LOCUS       DAIGQM010000049        21956 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.049, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000049 DAIGQM010000000
VERSION     DAIGQM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.049"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..260
                     /locus_tag="NOA48_001886"
     CDS             <1..260
                     /locus_tag="NOA48_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790144.1"
                     /translation="AAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNP
                     GNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            505..1530
                     /locus_tag="NOA48_001887"
     CDS             505..1530
                     /locus_tag="NOA48_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790145.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLRIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            1824..2933
                     /locus_tag="NOA48_001888"
     CDS             1824..2933
                     /locus_tag="NOA48_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0790146.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASANTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            3016..3912
                     /locus_tag="NOA48_001889"
                     /pseudo
     CDS             3016..3912
                     /locus_tag="NOA48_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            3928..4752
                     /locus_tag="NOA48_001890"
     CDS             3928..4752
                     /locus_tag="NOA48_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0790147.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINIFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGGKL"
     gene            4784..6094
                     /locus_tag="NOA48_001891"
     CDS             4784..6094
                     /locus_tag="NOA48_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HCI0790148.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSRAYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            6242..7501
                     /locus_tag="NOA48_001892"
     CDS             6242..7501
                     /locus_tag="NOA48_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0790149.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            7511..8383
                     /locus_tag="NOA48_001893"
     CDS             7511..8383
                     /locus_tag="NOA48_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0790150.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            8395..9225
                     /locus_tag="NOA48_001894"
     CDS             8395..9225
                     /locus_tag="NOA48_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0790151.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            9265..11448
                     /locus_tag="NOA48_001895"
     CDS             9265..11448
                     /locus_tag="NOA48_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0790152.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLQERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            11509..12729
                     /locus_tag="NOA48_001896"
     CDS             11509..12729
                     /locus_tag="NOA48_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HCI0790153.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKYSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVCLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            12726..14186
                     /gene="gtfA"
                     /locus_tag="NOA48_001897"
     CDS             12726..14186
                     /gene="gtfA"
                     /locus_tag="NOA48_001897"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HCI0790154.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVTQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            14263..15369
                     /locus_tag="NOA48_001898"
                     /pseudo
     CDS             14263..15369
                     /locus_tag="NOA48_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            15691..15900
                     /locus_tag="NOA48_001899"
     CDS             15691..15900
                     /locus_tag="NOA48_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0790155.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            15893..16042
                     /locus_tag="NOA48_001900"
     CDS             15893..16042
                     /locus_tag="NOA48_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCI0790156.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            16196..16330
                     /locus_tag="NOA48_001901"
     CDS             16196..16330
                     /locus_tag="NOA48_001901"
                     /inference="COORDINATES: protein motif:HMM:NF026010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790157.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     "
     gene            16490..16861
                     /locus_tag="NOA48_001902"
     CDS             16490..16861
                     /locus_tag="NOA48_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0790158.1"
                     /translation="MTVMRLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPE
                     TASSIRTIELDDNTITFLKAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIV
                     GVHIIRIHGLRHSHASLLISQ"
     gene            complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOA48_001903"
     CDS             complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOA48_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCI0790159.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            18564..18797
                     /locus_tag="NOA48_001904"
     CDS             18564..18797
                     /locus_tag="NOA48_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCI0790160.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            18794..19201
                     /locus_tag="NOA48_001905"
     CDS             18794..19201
                     /locus_tag="NOA48_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0790161.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(20338..20856)
                     /locus_tag="NOA48_001906"
     CDS             complement(20338..20856)
                     /locus_tag="NOA48_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HCI0790162.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         7469 a         3359 c         4118 g         7010 t
ORIGIN      
        1 tagcggctaa attagtaaaa tttttaaaaa ataagaataa acgagtgatg gaacaattat
       61 cgattattgg atttgatgat attacttttg cagaattaat ggatcctgcg ttgacaacaa
      121 tacgactaaa tccaggtaac aagggggcga ttgcttttca ccaactgatt ggactggcca
      181 aacaagaaga aataaaaaat caagtactac tattagaggg agaattgatt tctcgagact
      241 ctgttcacaa aatcaaataa aaaagctctg tgaaataagt atagttaaca ataaaatatc
      301 cgaacgatag agagaatgaa ctgtgatcta gcagttcctc gtcggaaatt cactagaatt
      361 agcattattt actctaaatt gttcggatat tttttcttgt ttttaattat gattacagtg
      421 cctattttta acgaaatttg cttattttca aaatgtatga ttatatttta gtaaacactt
      481 tcaaatatga aaagaggagc tattatggta ggaattaggg atgttgcaaa acgggcgggt
      541 gtgtccattg caacagtatc gcgcgtgcta aatgaggatc cgacactttc agtaaccgat
      601 gaaaccaaac gaaagattgc agaatcggtt aatttttatc attatgtcaa aaaaagtccc
      661 gttgcaaaaa atttaacaaa tattgcatta ataacgacag tttctgaagt agatgagttg
      721 gaagatccct attttcgaac gattcgcaga gggattcaag tcgaagcaga acaaagcaaa
      781 gtcaatttga agaaaattat tcgtttgtca gaaacaccgt tggagcaaga tgatttgcta
      841 aaatgtcaag gtgtgttgat tattgggcag gtgctatctt ctgtgattga agaagtatca
      901 gcaattaatt cgaatgtcgt agtgattgat gaccctagta ttgaagctga agtagatgca
      961 gtttatactg atttaacaaa agcaacgaat cagcatttag atcgattgta taaaaaagga
     1021 caccgaaaca ttgcgtttat cggaggagga cgtgttcgtt tagatagcca aggaaataaa
     1081 cacgtgtcag atgatgatta tcgaaaaata gcctatgaga cgtggatgaa acaaaaagga
     1141 ttagaaaaat atagtcaaat ttatttagaa ggctggacca cacttgacgg aatgcaggca
     1201 gcagatttac ttttgaaaaa acatgctaaa gataagttgc cgactgctat catggtagga
     1261 aatgatccta ttgctgtggg ggtttatcgt tcacttcaaa aaaatggtct acgtattcca
     1321 gaagatattt cgattgtgag ttttgataat attgaagttg ctgaattttt aacacctgca
     1381 ttaaatacgg tgaatgtgaa tacagaagaa attggaaaac tagcagttcg catggttaat
     1441 gaacgaataa aagaagttag aaatgtttcg atcaaagtga ttgtttctaa taatattatt
     1501 gttagagaaa gtgaaaaaaa tatcgattaa aaaagtaaac atccaaaaaa ggatgtttac
     1561 ttttttgttt actaatattt ttagtaaaaa atctcgacaa aacattaagt aaacagttat
     1621 ggtgttgtta acaaaaagaa aacgcattca aaacaggagg aattaagatg aaacatttca
     1681 aaaaaatagc tttaacaggg atagctgttt taactgggac attactcgca gcatgtggtg
     1741 ggggagatag taattctaaa gacgggcaag taactttaag ctatgcgagt tgagatactg
     1801 accaagctcc aggactaaga aaaatattag atgaatttga aaaacaaaat cctgatatca
     1861 aagtagaaat ggagacaacg ccttgggatc aatattgggt taaattagaa gctgcaacaa
     1921 cgggaggtaa tatgccagat gtagtaacca tgcactctag cgaatcctat aaatatatgt
     1981 cacagaatgc tttgatggga cttgatgatg ttatcaaaga aaatgatatt gacatgggaa
     2041 actttactga aggaattgct gatttctata cgcttgaaga cgaactatac gcaatcccta
     2101 aagatgcttc tgtagtgggg ctatggtaca acaaagaatt atttgataat gcaggtgtcg
     2161 attatccaga tgaaacatgg acatgggaaa cactcagaca agctgcaatt gatttaacag
     2221 atgaatcaaa aggcatctat ggttttgcat cacatattgg aacagagact ggctactggc
     2281 catttattta tcaaaatggg ggagaagtat ttgccgatga caatacaaaa tcaggtttga
     2341 ataccccaga agcacaagaa gctttagctt tttatcgaga tattgcactt gttgatcatg
     2401 cttcaccaac aattacagaa ttacaagatc ctgataagtt aagtcgtttt caatcaggta
     2461 gattagcaat gatgattgaa ggaaactggt ttgcaccggg atttttgaaa aatgactatc
     2521 tagttgaaaa tgttgcttct gccgtgttac ctaagggaaa agttaatgca acaattacaa
     2581 atggacttgg ttgggctgcc agtgcgaata caaaataccc agaagaagtg aaaaaactaa
     2641 tggcattttt agctagtgag gacgccaata aaatccaagc ggaaacgggg gcatcaatcc
     2701 cagcactaaa aggctttgaa gacgagtggg ctgcttcttc agatacaatt gatttgagtg
     2761 cttttggaaa aatgttggag tatggagtcc ctcgtccata caataaagat ggattacgag
     2821 ctgaacaagc agaagttcaa attattaacc gtattctgtc tggtgaagta actgttgaag
     2881 atggaaccgc tcaaattgaa aaagaagtca atgcgatatt gagcggaaat taaattagtt
     2941 aattatacaa tatacaggcg aaaggattct atttcgtctg tatattaatg gatgaatacc
     3001 aaaaaggggg atattatgaa aaatcgaatt tttggaaaat atcgtaaaga tcaagtgata
     3061 tggggctata tttttatttt tccaacggca ttaggattaa ttttattaaa tatatggcca
     3121 gcaattcaaa cagcaatttt aagttttcaa aaaacggtag ggttcggtga tactgaatgg
     3181 gtcggattaa gaaattacca aaaaatgttt gcagacggtg aagtttttca gtctttatta
     3241 aacacattaa tttatgcagt ggtttcgata cctagtattg ttgtattatc cttgttggtg
     3301 gcagttttaa tgaatagaaa agttaaagga ttgtcgattt atcggacaat ttattttcta
     3361 ccagtcgttg ctgcaccatc cgcagtcgca atgatttggc gctggatgtt caataatgat
     3421 tatggactga ttaataacat gttggctaaa ataggtctcg atggaccagc atggttaacg
     3481 gatccatcga ttgcgattta ttctattatc attgtaggag tttggagtgc tattggttat
     3541 aacatggtgt tattactagc cggcttataa gaaattccta aagattatta tgaagcagcg
     3601 gaaattgatg gtgctagtcc aatccagcag tttttcaaca ttacgttacc attagttaca
     3661 ccaacattat tttttgtagt tgtaacaaca gttatcaatg ctttccaagt atttgatgtt
     3721 atttttatga tgattactcc taatagtacc gccatgttta aatcacaatc attagcctat
     3781 ttattctata aacattcatt tattttaaat gacaagggat atggttcggc aatcgttatg
     3841 ttccttttag tgattatatt aattattact gcaattcaaa tgaagttgca gaaaaagtgg
     3901 gtaaactatt aaggaggcta tcaaattatg aaaaataaat ttttttcaaa tgcgccaatc
     3961 catatcatgc ttattttagg tggtattgca atggcattac cttttatttg gatgatttta
     4021 acttcaggga aaacgttggt tgaatctacc caaattccac ctacaatttt ccctgagaaa
     4081 tttcagctaa gtaactatca acaagtactt gatttattac cattcatggc tttttatatc
     4141 aatatatttt taatggttgt tggacgagtg attggctcgg ttttattttc agcaatggct
     4201 gcatatgctt gtgcgcgtct aagttttcca gggaaaaata tccttttcag cttagtactt
     4261 attcaaatga tgattcccgg ttccattttt attactccac agtatttatt agcacaaaaa
     4321 ttgggtattt taaatacaat tccagcatta atattaccag gggtagttag tgcgtttggt
     4381 acgtttttat taagacaatt tttcttaggt ttgcctgatg aattggagga agcggcctat
     4441 ttagaaggtg ccaatatttg gacgatcttt ttcaaaatta tgttgccgct tgctaaatca
     4501 ggattggttg cacttggaat attcacagcg ttgtttgcat ttaaagattt aatgtggcca
     4561 ttgattgtca atacttcaat tgataagatg cctttagctc cgggattagc aaacttacaa
     4621 ggacaatatg ccacgaactt cccacaatta atggcaggtt cgttattagc aatttggcca
     4681 atagttgtga tattcatcgt tttccaaaga aaattcattg aaggaattgc tacaacaggt
     4741 ggtaaattat aaaactatta attagtgatt ggagagtaag tacatgacaa aaattacatt
     4801 tattggtgca ggaagtacta tttttgcaaa aaacgtatta ggcgatgcga tgttaactcc
     4861 aagtctacaa gatgcacata ttgcattgta cgatattgat gaaaaacgac taaaagaatc
     4921 aaatttaatg cttaaaaata ttaataaaaa ttcgaatgaa aatcgtgctg atattgtttc
     4981 ttattatgat cgcaaagaag cgttaagaga ggctgatttt gttatcaatg ctattcaagt
     5041 gggtggttat aaaccttcaa cagtgattga ttttgatatt cctaaaaaat atgggttgcg
     5101 acaaactatt ggtgacacca tggggattgg tgggattttt agaaccctac ggacactacc
     5161 agtaatgtta gactttgcta aagaaatgga agaagtttgt ccaaatgctt ggttattgaa
     5221 ctatacaaat ccgatggcga tgttaaccat gggtgtttta aaagcgacga gtattaagac
     5281 tgttggttta tgtcatagcg ttcaagtatg cgtaccagaa ttgtttgagc atttaggaat
     5341 agccgatcaa tatgacttaa atgactttca atggaaaatt gcaggcatta atcatatggc
     5401 attcttgttg gaaattacaa aaaatgggga agatttctat ccaacaattc gtcagttagc
     5461 tgcagaaaaa ccaaatccac atccagattc tgtacgtttt gaattgttga aacgttttgg
     5521 ttactatatt acagaatcaa gtgaacacaa tgcagaatac catccatact ttattaaatc
     5581 aaaataccca gaattgattg acgaattagg gattccgttg gatgaatact tacgtcgttg
     5641 tgaacaacaa attaatgatt gggaaagcat gcgagaggac attgtaaata atggggagtt
     5701 aacacatacg agaagccgtg catatgcttc atatatcatg gattctatta cgacaggaac
     5761 tccgtcagtg attgcaggaa atgtcttaaa taaaggctta atcacaaact taccgacaga
     5821 tgtttgtgtg gaagtacctt gtttagtcga taaaaatggc gtgcaaccaa cctatgtcgg
     5881 tgaattgcca acacaattag ctgctttaaa tcggacgaat atcaatgttc aagaactgac
     5941 agtagaagcc gctttaacac tagataaatc aaaaatttat caagcagcgt atttagatcc
     6001 acatctatca tctgaattgt ctttaacaga tatcaaaaat ttagtggatg atttaatcga
     6061 agcacatggg gactatttac ctgaatataa ttaaaaagaa gctgaaagag taaggaattt
     6121 tcaattcctt actcttttct tagttaaatt tagtaaaaat attgacaaaa cacttagtaa
     6181 acagttacat tagtgttaac aaaaagaaaa cgcattcaaa ttgtataagg aggagcataa
     6241 aatgaagtgg tctaaaaaaa ttattttagc ttgtatagca ctaggagcaa cgatctcttt
     6301 gactgcttgt ggaaaaaatc aggaagatgc aagcggtaag gtagaaatag agttttttaa
     6361 tcaaaaaaaa gaaatgactc aaacgattca ggagattgct aaagattttg aagcaaaaaa
     6421 ccctgatatt catgtaaaag ttgtggatgt accgaatgct ggtgaagtaa ttaaaacacg
     6481 tatgcttgca ggcgatgtac cagatgtcat taatctttat cctcaaagta tagaattgaa
     6541 agaatgggcg aaagctggtt atttagagga cttaaccgaa gaaccgtatt tagagaatat
     6601 caaaaatgga tatgcacaac gttttgctat tgaggatcgt gtatatagca taccattaac
     6661 cgctaatgtc tatggttttt actataacaa aactgctttt gaggaaatgg ggattcaagc
     6721 accagaaact tgggcagaat ttgaaaaaat agtagctgag attaaagatc aaaacaaagt
     6781 accgtttgcg attgcaggag cagaaggctg gactttaaat ggttatcacc aactagctat
     6841 agcgactgct gctggtggtg aagaggaagc gaacaatgtt tggcgtttct cagaagttaa
     6901 tggaattaat gctgaaagca aagaaatgca aaaagatttt aatcgattag atttgttaag
     6961 agaaccaaaa gctttgcaaa acaactggca aggtgccggt tataacgata cagtagttac
     7021 ttttacaaaa ggtgatgcgt tgattatgcc gaatggttca tgggcaatgc cgatgattca
     7081 ttcacaaaat ccagattttg aagtaggaac ttttcctttt ccagcagatg aagcaggtca
     7141 aagtctaacg attggcgcag gagacctagc cttatcagtt tctgcaactt ctcaacataa
     7201 agaagaagcc aaacgttttg tagaatatat gacaacacct gaagcgatgc agaaatatta
     7261 tgatgtagat ggtgcaccgt gtgctgttga gggcgttatc gagaatactc aggattcacc
     7321 attaagtggt ttaactgaac ttgcttttac tgatcgtcat ttagtttggt tagccaaaga
     7381 ttggaatagt gaaaatgatt tttatacctt aacaacaaat tatttacaca atggcaatca
     7441 aaaagccatg attaacgcat taaatgcttt ctttaatcca atgaaagctg acggaaggta
     7501 ggaaaataaa atgaaaataa aagaaatttt aaatcgttac tgggcaatca tttttgtagc
     7561 aattccaatt attttgcaga tgattttttt ctactttcca atggttcaag gtgcttttta
     7621 cagtttaact aattggactg gtctgactta taattttgat tttgtgggtt tgaacaatta
     7681 taagattctt ttttctgatc cgaagtttat caaatcgatt ggcttcactt taattgtgac
     7741 gctttgcatg attgctggac aaattggttt tggtattttg attgcgcggg cgttgaacgc
     7801 aaatattaaa gggaaaacat tctttagagc atggttcttt tttccagcgg tcttatcggg
     7861 cgtggttgtt tctttagtat ttaaacaaat ttttaactat ggtttaccaa aaattggtag
     7921 tatgttaggc attgaatttt tacaaaccag tcttttagga acaacatggg gagcgatttt
     7981 tgcagtaatt tttgttttac tttggcaagg aattgccatg ccagtcatca ttttcttagc
     8041 gggttttcaa agtattccac aagaaattat tgaagctgct agaatggatg gggcgaatga
     8101 taagcaaatt ttttggaata ttgaaatcac ctacttatta ccaagtattt caatggtatt
     8161 tattatggca ttaaaaggtg gcttaacagc atttgatcaa atttttgctt taactggtgg
     8221 tggaccaagc gatgccacaa catctttggg gttacttgtt tataattatg cttttaaaaa
     8281 caatcagttt ggttatgcga atgctattgc tttagtctta tttatcttaa ttgggattgt
     8341 ttcactggca caattaaaat tatcgaaaaa atttgaaatc taggaggttt cccaatgaaa
     8401 acatcaaaag aaaaaaatat ttctaaatac ttgcttttat tattaggggg cttcatgatt
     8461 ttagttccct tagtttcaac gctattcggt tcatttaaaa caacacccga tattatgaat
     8521 aatttctttc gttttcctaa tccagcgact ttggaaaatt tccgaagatt gttagcggat
     8581 ggaattggtc attacttttg gaattcggca atcatcacaa tcattgcagt agttgctgtg
     8641 acagcaatta ttcctatggc tgcttattca ctagcaagaa aaatgactcg tgggaaagca
     8701 tacggattga tgtatttatt tttaatttta ggaatttttg ttcctttcca agtaattatg
     8761 attccgatta ccgttatgat gagtaaaatt ggtttagcaa atatgtgggg attaatctta
     8821 ctctatctca cttatgccgt accacagaca ctatttttat atgttggttt tattaaacta
     8881 aatgtgccta tcagtctgga tgaggctgct gaaattgatg gggctagtca ctttacaact
     8941 tatttcaaaa ttgttttccc aatgttaaaa ccaatgcatg cgacgactat tattcttaat
     9001 gctctatggt tttggaatga tttcatgcta ccattattaa ttttaaatcg tgattctaat
     9061 atgtggacac taccattgtt tcaatataat tatacgggac aatattttaa cgactatggt
     9121 ccaagttttg cttcctatac agtaggaatt gtcacgatta cactagttta tcttgctttc
     9181 caaagaagta ttatagctgg aatgagcaat ggagcagtga aataaccaat aaattattct
     9241 cattataaag gagttcataa acttatgatt atatttgaca atcacacaca aacatttcat
     9301 ttacaaaata aaaaaattag ctatctatta ggaatcgaag aaaataatta tttaacgcat
     9361 ctttattttg gaaaaaagat tacgcactat tctggtgggt atcgctaccc ccgaacagat
     9421 cgttccttct cacccaacaa tgcaaatgcg caagatcgtt tattatcttt agatacatta
     9481 ccattagaat ttccaggata tggacatggt gattttagag aaccggcgca taatattaaa
     9541 ttaggaaacg gtagtcgtgt aaatgatttt cgttatgata gctacgaaat tcaaaaagga
     9601 aagcccagct tagcgggatt gccagcctta tatacggaag atgatgatga agctgaaacg
     9661 ctgattattc aattgaaaga cgcgattagt ggattgactt tacagttgtt ctacacaatt
     9721 tatcaaaatc acagtgtaat tattcgttct acgcaattag taaataatag tgatgaaaca
     9781 gtggagatta accgcttagc tagtcaatca attgattttc caaatcgtcc actcgagtta
     9841 attcatttaa atggtacctg ggcaagagaa cgtcaaatga ctagagaaaa aattcataca
     9901 gggataaaag tattagatag taaacgcgga tcaagcagcc atcaacaaaa tccgtttgtt
     9961 gctttagtag atgccaaaac agatgaattt caaggagagg catatggatt taatttagtt
    10021 tatagcggta atcacgaaac ggtgattcaa aaagatccat ttgaccaaac acgggtcatt
    10081 atgggaatta attcatttaa ttttggttgg caactaaaaa ctggcgactc atttcaaacg
    10141 ccagaagtcg tgatggttta tagtaatgaa ggtctgaata cgttatcaca gacgtatcat
    10201 gaattgtata atcaccgttt aattcgtgga aactatcgtt tacaagaacg tcccacgtta
    10261 atcaacaact gggaagcaac gtattttgat tttaacgaag aaaaaatcat gaatattgtc
    10321 gatgatgcga agaacttggg cattgaaatg tttgttttag atgatggttg gtttggcggt
    10381 cgtgaaaatg acttcacttc attaggtgat tgggttgaaa cagaaggcaa acttgcttgt
    10441 ggtttggaaa atttagccaa gcaagtgcat gataacggga tgaaatttgg gatttggttt
    10501 gaaccggaaa tgatttctga agatagtgaa ctatttcgag cacatccaga ttgggcattg
    10561 ggtattccag gtcgtgaccg ctcaattagt cgaaatcaat atgttcttga tttttcaaga
    10621 caagatgttc gtgataatat ctatcaacaa atgacggcga tttttgatcg tgtaccgatt
    10681 gattatgtga agtgggatat gaatcgaaat atgacagaag tctattctgt cttgttggac
    10741 tcaacgatgc aaggtgaagt ggctcatcgt tatatgttag ggttatatga atttttagaa
    10801 aagttaacaa cgaattatcc aactatttta tttgaaagtt gttcgggtgg aggcggtcgt
    10861 tttgatgcag gtttcttgta ttacatgcca caaacttgga cgagcgacaa taccgatgcc
    10921 gtggctcgtc tgaaaattca atatggaacc agcttagtgt atccaatttc aagtatgggt
    10981 gcgcatgttt cagcagtccc aaatcatcaa acaggaagag aaacgagttt aactattcgt
    11041 ggcaatgctg cgatggctgg tgtttttggt tatgagctag atctaacgca attaacttct
    11101 gaagaaaaag cagaaattaa agaacaagtt gccttttata aaaagcatcg ccaacttttg
    11161 caatatggaa ctttttatcg cttggaaagt ccgtttgaag gcaatgatac tgcatggatg
    11221 tttgtctcaa aagaccaaac agaagccatg gtcttttatt tccgagtatt agcagaagct
    11281 gcgcatccat tagtcacatt gaaattagca ggattagcag aagaagcaac ttatcaaatg
    11341 gaagatgtaa catttgctgg cgatgaattg atgaatctcg gtttttatat tgactcagaa
    11401 ctacatggtg attatgcgac acaacgcttt tatttgaaac agatatagta gcttgaattt
    11461 acaatataag tgcaacacca aaagagactc attccaaacg aagaaaatat gttttattta
    11521 cacgcattta ctaaaaagca gcctgatttg aattgggaaa atgaagaagt acgtgaagaa
    11581 atctatgcaa tgattaacta ttggttagat aaaggactag gcggatttag aatcgatgcg
    11641 atattaaaca tcaaaaaaaa actagagtat ggcatctttg aatctgatgg agaagatggg
    11701 ttagccttca ttgggccctg gattcttaat cagtcgggca ttgaagtgtg gttaaaagaa
    11761 atgagagagc ggacatttaa accacataat agtatgacgg tagcagaagc cgatgttcct
    11821 aatgaacgtt tagatgaata tattggtgaa gatggctatt attcgatggt ttttgatttt
    11881 agttatacgg atattgatgt acctgaaact ggtgaatggt ttaaatatag ccaatggaca
    11941 tggacggata tgcgtaccaa tatttttacg aatcaattag ttacgcaaga taaaggttgg
    12001 ggcgccttat atttagaaaa ccacgatcaa ccacgttcaa ttaataaata tattccagaa
    12061 gaatggatca atgattatag taaaaaaatg ttggcgacgc tttttatgtt actaagaggt
    12121 acccctttta tttatcaagg acaagaacta ggaatgacca acatagaaat ggcatcatta
    12181 gaagattttg atgatgtagc tacgcattct cagtataaac gggcattaga atatggattg
    12241 gcaccagagc aagcattgaa agctgtcaat aaacgaagtc gggataattc tcgcacacct
    12301 atgcaatgga atacgcaaaa aaatgccaga ttctcaactt ctgataatgt atgtttaaaa
    12361 gtaaatccta attatccaga actcaatgca gaagctcagt taaccaatca acagtcggta
    12421 ttcaattatt atcatcaatt aattaaatta agaaaaaata gtgtatacaa agacgtgcta
    12481 atctacggac aatttctacc agtgaaagat aaaaatgaac atattttgct ttatgaacgc
    12541 caattagaag ataaaatcgt attagttatc ttaaacgtta cagcaacaga acaagaatat
    12601 tatgtagatg aacagtacca acaagtatta atcaataatt atgaagatgt tttattagat
    12661 caaagtcgaa aattgcgttt acgaccgttt gaaagtattg tattagctaa ttatggagga
    12721 caattatgaa aattaaaaac gaagcaatgc tcatcaccta tgcagatagt ttaggaaaaa
    12781 acatgggcga attaaaacaa gtcttagaca aacatttaca aggtgttatt ggtggtgtac
    12841 atctgttgcc tttttttcca tcgacaggtg atcgaggctt tgcgccgagt gattatacga
    12901 cagttgatcc agctcttgga acatgggaag atgtggaagc attaggtgaa gattattatt
    12961 tgatgtttga ttttatgatt aatcacattt ctcgtgaatc aaaatttttc caagatttca
    13021 aaaaaaacca tgagcagtca ccatacaaag aaatgtttat ccgtattcat gaatttttcc
    13081 cagaaaatcg accaacacaa gaagatattg atttaatcta caagcgtaaa gacaaagcgc
    13141 cgtttcaaac ggtagaattt gcggatggta cgacagaaga ggtttggaat acctttgggg
    13201 aagaacaaat tgatttagat gtgaccaaag aagttgtgaa agaatttatt cgagaaacca
    13261 tcaaagatat ggcgaaccat ggctgttctt taattcgatt agatgcgttt gcttatgcga
    13321 ttaaaaaatt agataccaat gatttcttcg tggaaccaga tatttgggaa cttttagacg
    13381 aagtgcgtca agaagcagcg aaatatgacg tcgaattatt accagaaatc catgagcatt
    13441 attccattca aatgaaaatt gccaatcatg attattatat ctatgacttc gccttgccaa
    13501 tggtcactct gtattcactt tatagtggaa aatcagaacg tttagccaat tggttgaaaa
    13561 tgagtccgat gaagcagttt acaacattgg atacgcatga tggaattggt gttgtggacg
    13621 ctcgtgattt attaacagat gaagaattgg attacacctc tgaggaattg tataaagtcg
    13681 gggcgaatgt gaagaaggtc tattcaagtg ccaattacaa taatttagat atttatcaaa
    13741 ttaacagcac ctattatagt gcattaggcg ataatgaccg tagctatctg ttagcacgtg
    13801 cgattcaagt atttgcgcca gggattccac aaatttatta cgttgggtta ttagcaggaa
    13861 aaaatgatat tgaactgttg gaagcaacga aagaagggcg taatattaat cgtcattact
    13921 atgatttagc cgaaattgaa gaagaagtgc aacggccagt gactcaacaa ttatttgcac
    13981 ttttaaaatt tagaaatgaa tctgcggcgt ttgatttgga tggaacgatt gaagtagcaa
    14041 cgccatcaga atcagaaata gtgattacac gtaaaaataa aaacggtagt gatagtgcaa
    14101 cattaacggc taacttggat acgaaagaat ttatcattga gtctaaagat ataaaaattt
    14161 tcactagtgt tgcattaaaa ttttaaccta ttccatagaa caaaaaatcc tttatactag
    14221 cacttggatg acttatccaa gaccaataaa aaggactcat acatggataa gtataaaaca
    14281 aatacagcat ttaataaatg gttttctgcc ataaaattag gaaaactttc tgtcaactcc
    14341 caaaaatgta tttttgatta caattcgtat cgtaaaaaac tgtcttttga agctgtgctc
    14401 aagctctttc tctacgcagt taatgaagaa aaagaaagtt tgcgtgattt gagtacagct
    14461 cttatcgacc gatcgctcca actagaaacc gatgtgtcat cgattagtca tacccaattg
    14521 tctcgagcat ttaatgcact tgaacctaaa gtgttagaag aaatttttca acaactgtta
    14581 gaaaaagttc aacatcaaat caaaccaacc aagcgaaatc atctgtatct gattgattcc
    14641 agtacgtttt cgcttagttt aaaacgtcat aagtgggcga ctttccgtca aacaaaatca
    14701 ggtgtcaagt tacacttaaa ctattgttat atggacgata ctacgatgta tccaactgat
    14761 tttaccttaa caaatgccca tgaacatgat ctcaatcaac taccagtatt ggtgaatcaa
    14821 ccagaggcaa cttacgtgtt tgatcgtggg tattaggact ttgaaaagat ggatcagatg
    14881 cattgggatg gctatttctt cgtcactcgg attaaaaaaa acaccaaagt tcacgtgata
    14941 gatactctgg aaacatcgcc agaaacagaa attctacgag acgagctggt tcgtttagga
    15001 tctaaaacct atctaaccgc caatttccga ctagtcactg ttcaagataa gaacggacgt
    15061 gtgtttcaat ttatcaccaa tcgaatggac gtctcttcaa aagaaatctc tgatatgtat
    15121 cacgctcgtt ggcaaatcga attgtttttc aagcacatca aacaacacat gaccattaaa
    15181 accttctttt ctcaaagtga aaaaggcgtg cagaatcaat tgattttaac gatgatttcc
    15241 gctctcctca cgtttctcat caaattggag acgaaaacgg aaaaatcagt gttccaaatc
    15301 aaacgattct ttcgttattt actgtttcag ccctttgaat gttgtctaga aaaattaatt
    15361 cccacatgag aaaaaagaaa tttggctcgt tacttttggt tttcagttga ataacagata
    15421 aaaaattttc tggaaaaagt catcctctgc gtcagcacag ttttttttga cttattttca
    15481 gaggaaatag ttttcagaat attctaaaat gttttatgca acactagtga tattttttag
    15541 aattagattt ctaatgtgca ttttttgagt attaaggagc aagtatacaa agatttataa
    15601 agctgattaa atttgaataa aaatatgcag gaacgctact atttttagta gtgttctttt
    15661 ttatatttga ataaaaaatg tggtggttaa atggtggtta taacaaaaaa tgaattaatg
    15721 aaattaggtt atgggaagta tcagtctgag agaatcatac gacaggcaaa agcaattatg
    15781 gtttcaaaaa gctataccta ttacgaaaat agaagattag gactagtacc tgttgaatct
    15841 gtagaagaag ttttaggtat gaagatagag gtagaggagg attttcagaa tcatggttaa
    15901 ttttaaaaaa gataaaaatg ggaaatatca ttttactgct agtttgggat tcgacaaacg
    15961 aacagggaaa agagtacaaa aaaacgtaga ggggttaaaa cagttaaaga agaaaaaaag
    16021 cgtataccga acttgtttct aattatggaa aagaagcaga aacttctcaa agtactatgt
    16081 tgtttgagga gtttttttat aaattattcc taccttatta tcaagggaaa gtagaagaaa
    16141 gaacatataa aaatcggtta tctacaatca aaaaaacttt tcttatttct ttaaaatgga
    16201 gttaagagaa atacgtccaa ttgacattca aaagtggcaa aataatttat tgagcaaata
    16261 taaaaattct tatgtaagaa acatgtatgg gatttttcag atgtcattag atcgagcagt
    16321 tgttttgtga ctacttgaaa aaaatcctgc aaaagttatt ggaaatgtga agaaaaggaa
    16381 aactacagtt gatttttgga caaaagaaga atttacaaaa gttatttcaa ctttttatat
    16441 tgatgatttg taccaacatt ttggttttat ttgtatgtgg ttacttttta tgaccgttat
    16501 gcgtttggga gaagccactg cattaacttg gaaagatatt gattttgaaa ataaaaactt
    16561 gcgtgtgaat aaaacactct attataagag agccaaaacc tatgagtttg tagaacccga
    16621 aacggcttct agtattcgta caatcgaact agacgacaat acaattacct ttttaaaagc
    16681 ttggaaggag cgtcaagttt caataggagg catgtcgttt gtactttctt ataatggaac
    16741 acctactcag aaatatacaa tccgtcatat tatgagaaga catgcaacga tcgttggtgt
    16801 tcatataatc cgcatacacg gattaaggca tagtcatgct tctttgctta tatcacaata
    16861 aaaagatgca cttcgaatta aagaaaggtt aaaacatgct gatgtacaaa cgactttagg
    16921 aacttatggt catttgtatc taaattcatt gagagagata acaaatgatc ccacagatta
    16981 tatccaaact aatttttcta aaatcaaacc gacacctatt tacgataata aaaaataaat
    17041 gataaacaaa agtaggatca caccaaaaga aacacactag aaaaactata atacaggctt
    17101 ttctagcgtg ttgtttctta tttccgccta tttatacatt atactcataa agcatttaat
    17161 gcatcgatcg tagccgcatt gtctatatgg gtatataaag ttgttgtatt ggtacttgaa
    17221 tgtcccaatt gttgggcagt taataccaat gaatttgtct gttggtagag tctagtagct
    17281 aatgtatgac gcagtttgtg agggctgact tgaattctaa agccttttga atattttgct
    17341 accatccgtt cgattgcaat accggatata cgcttggctt ctccttggta aattgctaga
    17401 aataaagctt tttcgttttc tgttacttta tatcgttctt tccgaatagc tagataatta
    17461 gctaaatatt ccattgcgaa tgctgctata ttgacagcat ctcttttatt tccttttcta
    17521 gttactacca cattattctt atctaaagat aggtcatcta aattaatatt tataacctcg
    17581 gagagtctca atccagatcc taaaatcagt gcattgatcg ccaggtctct ttctacatct
    17641 cgttgataat agatcaaagc tcgtttactc aaagtatttt tatattcatt ggcaatataa
    17701 tctagataat tttgtgtatc cttatctaga aataattttt tctcaatggc attggcacgt
    17761 gcagctaacg tagttttatc tgtgatggtt gctacttgat ccataggatt attgtctaag
    17821 tatggttttc ctagaggatt attggaactt ttcgaaagat atttaaatag aacctttaat
    17881 gccgtgatat ttctattgat agtagaagta gatagaccta agttattatt atctttgagc
    17941 ttagtttttg ttgtctcttt ttttacattt tcttttgtgc gacgtttcaa atgagatttg
    18001 tacaagttta ggtcataggc agttaactgt cttatcgagg tgatagaagt atcaggaacg
    18061 atagactcac tcagaagcca ttcataaaag agcttataat tttttagata ttctaaagtg
    18121 gttcgaggtg attgatcttt atcctcacga tcttgaacaa aatcttttat ataatcgggc
    18181 atatgaagta tgattgtatc tattttttga tatatttctg tatttttcat gtcattcatc
    18241 ctttcaataa gtaggggaga agagtatctc tataattgga ctataccaat tatagaatgt
    18301 tttgtcaatt ggtatgctct aaaatttatt aatttgtttc aaaaaaagca tataaacagg
    18361 tatacgttta ataatttaaa ataaatggta tacataaata gggaaggaaa tagaagggag
    18421 caatctaaat tttttgaatt ttcttaatta attatataga aagaacaatc tttctataga
    18481 gttagacatg agagggacta tgcttgattt aaaatcaaca agcgtatata ctgtatatac
    18541 aaagaaaaag gagggagaag actatggcaa ttaaagaaag aaaatttagg gaagtgggga
    18601 actcagtagt attaactatt tcaaaggagt ttcttaaaga aaatgggtta aatcccggag
    18661 atacggtttt tttagatgaa gaaaaacttc gagcggcaat tacaaaaaaa caagccttat
    18721 ctgatgaaat tgatttagca atatctcaag cattaactga atatgatact acttttagag
    18781 agcttgtcga taaatgagta ttcattacct agaagccaaa gatattataa aaatgaatgt
    18841 aatccaaata aaaaaatact ctcctaatga accccttggt gtaaaggatg cgaatgcttt
    18901 agaaatgtgt gtagggcaac ttcgagcctc agcttttggt gaagaggttt atccttcgat
    18961 ttatgaaaaa gcagctatcc tacttataca attgataaag aaacatcctt ttcacaatgc
    19021 aaataaacgt actgctttct tagctacttt tgtctttttg aaaatcaatg gacagctttt
    19081 agctattgat caaaaagatg ctgtaaattt agcggtatat attgctacgt atgataagga
    19141 tttcgatcaa ctaaaatatg aagtgatcaa cactataaag acacatacgc agcccattta
    19201 aggagttact gtatgtgtct ttatagtgtt attagctgct atagcgaaat aattgaagta
    19261 aattacaaat agctataatt caaatccaag tatatagaaa acgtaaattt tctatatagt
    19321 tggattaaga taacgactat ttattttatc atatttttac tgtaccctat acttttactt
    19381 ggtatattta tgaataatcg caaatttacc cctatactac tagtttgtaa gttagattaa
    19441 taaaaatact aaagttattt gttcttttat taaatacacc tacaacttat aaattgatgg
    19501 tatttagata acgcgaaaga ataaaaataa cagctgatag taaagtttgt tgacgattgc
    19561 tactcaatcg aaagtgagtt agtgcgtatg aacttgcttc tgaaaactta tgaaatgaaa
    19621 gaccttttac atcttgcaga aatcgttact gggattaaac taagcaataa aaactaatgt
    19681 tcccctcatt ctttgaactt ctactatttg atttatttat tctgataaat gacgatttca
    19741 ccttcaggat cttcaaatcc cgtatagaat ttatttaaga tctcttcagt atcagtaata
    19801 ggataggcga taggccacat accctttgat ggttagaata aactgctcaa aatctgtatc
    19861 gtatgttggc tttagcatat taacaaaggc tatctccaaa ttataaacca taagcgttga
    19921 atcgttctta acaatttcaa ttcttcctaa cccaaagtca gaagatataa ttaccggact
    19981 tgccttaccc ttcatgtggg ttgttgagat tccatattta aagggaattg tcggtactat
    20041 cggcggtctg aaaaacatcc caaaaataaa aaaatctttc ccctgctagt ctcctaagtc
    20101 cctttgcagc ggatatggca ccataatctc attttatcga agtgagtcat ggtttatctg
    20161 ttggccaacc aaaattgata caatctaacg atgcaccctc tacggcattc taggggagtg
    20221 cacttgcatt cacccaataa aaaccggcag ttagcaaaga acttatgtag tcgtatgttc
    20281 ttactgttaa catacaagag gtctcctttc cacaattgct tagcagtaaa cgggaattta
    20341 caaagctaat ctcttccatt ttcttatctt tgttctaaaa gtcccaaatg gagcaactgt
    20401 atttacatga ataaatttat atacttccca tacagccgtt ttggttgcct cgtctgccca
    20461 ttttcttttg tgtgcagtga atagatcttc atcactcatt gaatcaatca tcatgttaat
    20521 atcatcaata ttacgattga gaatttcctc taattctttc aatggtagat gtgcataggt
    20581 atttgtaaac cacttatata actctcctaa ctgattccat ttaaattgat cagaaggcgt
    20641 tttaacagat aatccatttc tttcatcatt ttcccatttt agaattaaat tcgtccaacc
    20701 aacttgatat gctaaatttt cagcaggtgt tctatccact tcctcaactc ttttatcctt
    20761 caattcttca ggaatagttt caaattctaa aatatattta gtataagtcc tatttatttc
    20821 tttttttaat tcttctttat ttttatatgt tctcattata ttacctccat aaattcctaa
    20881 ttgtctcctt taattcatct ataatttcat ccacgatatt ttaatccgtt ctacaatgca
    20941 tatctgatat gcattgactg tctaactcat atgtgaatga tttataaaat atcccaacgt
    21001 ctcatctaaa gaaatgttga tcgtcagcaa ggagctaaaa aatacgaata tatttctttt
    21061 gtagtaaaat cggactggtt tgcatatcat tttcttcgta aatatcaaaa tcatgttaac
    21121 tactatcaat tactaataaa aactaccact ttaagcgtta agaactgtta agtttagtta
    21181 agtgaggata gttcacaaaa tccattgtta aacttcacga aagtggtaaa actcaaaatg
    21241 ctttatatag gattacagca tcgctctttc ttcgattgcg cgttgggtaa aaaatattat
    21301 gaagtaaaaa ttgacgatga cacgttcctt acggctcatc agatgaaaca gctacaaaaa
    21361 cgaaatgatc aactcgaaga aaatttaatt ctaaaaaagc gattgccata ttcacgcctc
    21421 gctcgacgaa ctattaaagg tcaagattta cctgaagatc atccttttta ggaaattgaa
    21481 gctttttatg ttgcacaatg catttataat actacaatga tgttttcacc agatattctt
    21541 ctagggtgcg gtgtaatgaa acagatacac ttgcaaaaga aaattcaccg cgaatttact
    21601 aaaattatga ataattatgt taatcttccg aaattttttt ccaaaattaa gggatcaagc
    21661 tggtgttata gattgtttaa ggttggcaaa aaaataactt ctttttaaac aattatagaa
    21721 aaccgatact ctgttaagtt ggttgacacg gtatcgattt ttatgacttt cttattctga
    21781 aacttcacta acggacagta cctaaaaagt ctatagtatg gacgtttacg agtactattt
    21841 tatcaaaaat gctgctcatt tcaacttata tgttttagtg aactaccccc acttagctaa
    21901 acctgacggt tcttaacgct tgaagtggga gcttcttggg aacagagcgt acttga
//
LOCUS       DAIGQM010000050        21740 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.050, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000050 DAIGQM010000000
VERSION     DAIGQM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.050"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            269..2434
                     /gene="acm"
                     /locus_tag="NOA48_001907"
     CDS             269..2434
                     /gene="acm"
                     /locus_tag="NOA48_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCI0790163.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2706..3191)
                     /locus_tag="NOA48_001908"
     CDS             complement(2706..3191)
                     /locus_tag="NOA48_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCI0790164.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3281..3626
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3671..4312
                     /locus_tag="NOA48_001909"
     CDS             3671..4312
                     /locus_tag="NOA48_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0790165.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4331..4966
                     /locus_tag="NOA48_001910"
     CDS             4331..4966
                     /locus_tag="NOA48_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0790166.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4984..5799
                     /locus_tag="NOA48_001911"
     CDS             4984..5799
                     /locus_tag="NOA48_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0790167.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6118..7554
                     /locus_tag="NOA48_001912"
     CDS             6118..7554
                     /locus_tag="NOA48_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0790168.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7743..10190
                     /locus_tag="NOA48_001913"
     CDS             7743..10190
                     /locus_tag="NOA48_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI0790169.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10420..11487
                     /gene="rlmN"
                     /locus_tag="NOA48_001914"
     CDS             10420..11487
                     /gene="rlmN"
                     /locus_tag="NOA48_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI0790170.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11680..12783)
                     /locus_tag="NOA48_001915"
     CDS             complement(11680..12783)
                     /locus_tag="NOA48_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0790171.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13336..13884
                     /gene="aac(6')"
                     /locus_tag="NOA48_001916"
     CDS             13336..13884
                     /gene="aac(6')"
                     /locus_tag="NOA48_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0790172.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14430..16091
                     /locus_tag="NOA48_001917"
     CDS             14430..16091
                     /locus_tag="NOA48_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0790173.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(16161..16508)
                     /locus_tag="NOA48_001918"
     CDS             complement(16161..16508)
                     /locus_tag="NOA48_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCI0790174.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16592..17533
                     /locus_tag="NOA48_001919"
     CDS             16592..17533
                     /locus_tag="NOA48_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790175.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17534..18577
                     /locus_tag="NOA48_001920"
     CDS             17534..18577
                     /locus_tag="NOA48_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790176.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18583..19653
                     /locus_tag="NOA48_001921"
     CDS             18583..19653
                     /locus_tag="NOA48_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790177.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19643..20596
                     /locus_tag="NOA48_001922"
     CDS             19643..20596
                     /locus_tag="NOA48_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0790178.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20608..21618
                     /locus_tag="NOA48_001923"
     CDS             20608..21618
                     /locus_tag="NOA48_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790179.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
BASE COUNT         7387 a         3700 c         4555 g         6098 t
ORIGIN      
        1 ttttgtaagt taaaaattgg aaatatagat tgaaaaaatg aaagcaataa gtaaaataaa
       61 atgaatatat gcgaaaaaat aatttacatt aggaaaaacc ttgtaaaaac agttttttgg
      121 catatttatt ttttataaat atttgtaaaa taactatcaa ttttttagtt aaaagattgg
      181 aaatgagtgg gggaggaatt gaagaaagga tttttgagag atgatatagt aggttttatt
      241 tttagttaaa ataggggaga tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat
      301 gttatttatt attactaata taacatcact gattcctgtt catgtctatg cggatgcagg
      361 cagagatatc agcagtaatg tcacttcgtt gaccgtggac ccaacgaata ttacagatgg
      421 aggaaacata aaagtaaaat tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga
      481 ttatctttgg atcaattggc caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga
      541 aatcccatta atgattgaaa ataaaaatgt tggaacttta acggtcagaa aagattctgc
      601 gcaggttgtg tttaatgaaa atattaaaaa cctagactca gtagaaggtt gggggcaatt
      661 tgagatacag gccagaaacg taaccgatac cggtgaagaa aatacgggac cattcaccgt
      721 gacgagcggt gataaaacag ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc
      781 tagcgttttt tattataaaa caggagacat gctacctgaa gatactaagc acattcgatg
      841 gtttttgaat attaacaata acggcactta tgttgaacaa ccagttaaaa tcagtgatga
      901 aatccaaagt ggacaaagat tagatccaag tacgtttgaa attaatcaaa tacacttagg
      961 tgaacagaag gtttatagag gagaagaggg aatccaacaa tttttacaag atttccccag
     1021 cgctacattt aatttttcag taactgataa ttacattgaa ataactatac caaaaaactt
     1081 tgtcaatctt aggaaaataa tggtgagtta taagacgatc atagaaaacc cagaacaaat
     1141 aaattttgag aatcattcgg aagcttggtt taaagaattt aataaacctg ctgttgatgg
     1201 agaaagtttc aatcatacag ttaaaaatat ttcagcttct ggtggagtca acggtacagt
     1261 tagaggcgaa ttgaagattt tcaaatatat caatgacaca gagattggta tcccaaatgt
     1321 gactttcgaa ttaagacgag cagatgaaca gcctattcaa ggacagtcta gtatcctgtt
     1381 gacttcgaat gaacagggag aagctagtat caaaggcctg caagtaggag actatgttgt
     1441 aaaagaaaaa gaagcaccca attggattga ttttgatcca ctaagttcaa atgaactcaa
     1501 attctccata aacgaaaatg atacagaggg agtcagttta cctatttata acaagaaaaa
     1561 ggttacgaac atcacagcaa ctaaaatttg gaacggtgga accactccaa gaccgagtat
     1621 ttattttaaa ttattcagag caagtacaaa caattgggaa ccagttcctg atgcagaaac
     1681 aaaacgatta gacaatggaa taacttcagt gacttgggaa gatatccaac agtatgatga
     1741 tagtggaaac gaatatacgt ttaaagtgca agaagtagat caaaacggaa atgattatgt
     1801 cccttcaggt tatcaaaaaa ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt
     1861 catttcagtc tcaggacaaa aaacatggga agacaatgag aaccaagacg gcaaacgacc
     1921 gacgacgatc acagtaaatc tattagccga cggtcaaccg atccaacaca aagaagtaag
     1981 tgaaaaagat gattggcgct atcgtttcac aaatctgcca aaatacagag acgggcaaga
     2041 aatcatctat actgtaacgg aagacaacgt gcccgaatac agtacgacga ttgacgggta
     2101 taacatcaaa aacagttata caccggaaaa aacaaatata tctataccag gtagccatat
     2161 aacaccgtgg aaaaattttc cagagaagac agagagagag aaaattagaa atctattctc
     2221 tcaaaaattg caaatatttg ctcatacagg agaatccagc gaacaaagaa gcaattatat
     2281 tagtaagaga gctgtaccta aacagataac aaataaatca aaaagcattc ttcctaaaac
     2341 aagtagtaaa aaatctagtt ttgctgtaat cattggttta ttgatagtaa ctatctgtgc
     2401 tgggatattc ttacaaaaat ataaaaaagt ttagttagaa tataatattt tttgttaaat
     2461 atgactgaaa tcaaaagaat aaaattccga tttataatcg aaaaaagaag catttttata
     2521 tatgcttctt ttttcgtaga atcaataaat atggatttgg ctaactatgg aagaatactc
     2581 gtattagttt tcagcgttca tactagttgt tacattgttt gattggccaa aagaatttct
     2641 gatatatttt gtgctaaata aagaaaaaga cgcttgaatt gggaaataag aaaactactc
     2701 tatcattaca aattttcata aactggcaga tgttctaagt aaacaagtat cttttcaaag
     2761 tcggaaaaat ccataatcaa cgtagtggta ttgatatttg gatgaaagcc tacggtatct
     2821 tgacgatcaa tagcagcatc gatcacgact tggatttttt tctctttgtc gtgcatcaat
     2881 gctaatggag tcactgtacc tgctggaacg cctaggaggt caggaagctg ttcttcagaa
     2941 acaaaagata agcgcttttc ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt
     3001 tcatcaggca agatgacaag atagatttgt tttccttttc ttgatttcaa taatagattt
     3061 tttacttgcg gaccaggtag ggaaaaaggg acatttttga ctgacgtaat cgcaggatga
     3121 tcgacttttt gaaaagagat acccagtttt tttagtagtt cataagcttc ttgttcggtt
     3181 gcacgactca tcgcgcatca ccctcctttt tttattagtg tatcataaaa aagagttgac
     3241 aaatgaaaaa taatcatgta aattacacgt aaagttaaaa caaatgacat cgaaaagaag
     3301 agtagccgtt aggtgttttt agagagtctc tggttggtgg aaagaggcag cagttaaccg
     3361 tgaaacacat cttggagtcg attttctgaa gcgtatagta ggaaaatccg gggagcccgt
     3421 tacagctgcg gtcgttgcta gatgaccaga taaggctggc ttttccgtga ggagtcggta
     3481 aaaaaaggtg gaaccacgtg attaacgtcc tttgatcttc ggatcaaagg actttttgtt
     3541 ttcatctgaa cggcaacgac tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt
     3601 ggaaccacgt ataatacgtc ctcttggcat ttgccaagag gattttttta ttttaaagga
     3661 ggaaaagaag atggagtatt tgattgaagt tatgccgcaa ttattagtag gagcactcac
     3721 aacattgaaa ttatttttat ttaccttgat tggctcatta ccattaggga ttgttttagc
     3781 attaggattg tctttgcatt ttaagccgct acgctacttg cttcaaacat atgtatgggt
     3841 tatgcgggga acaccgctgt tgttgcaact gatttttatt ttttatgggt tgccgacgat
     3901 tgggatcgtt tttgatcgtt tcgaagcagc actcattgcc tttatcttaa actatgcagc
     3961 ttattttgca gagatctttc gtggagggat acaatcgatt cctcaaggtc aatatgaagc
     4021 agcgcaagtt ttgcaattaa gtccctttca aacggtgacg aaaatcgtca tcccacaagt
     4081 gacaaagatt gttttacctt ctgtagggaa tgaagttatc aacttggtca aagattcttc
     4141 cttgatctat atattaggtt taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg
     4201 cgacgcgact ttactgcctt tgctaggcgt ggcaatcatc tatcttacat tgactggtat
     4261 tctaacaatc gtaatgaaac aagttgaagg aaaattaaat tattaccgct aactgatagg
     4321 aggaagaaat atgattgaat tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat
     4381 caaagatttg aatctaatca ttccagatgg gaaaacatta gctatcgtag gtccttccgg
     4441 tggcggtaaa accacgcttt tacgtatctt ggctggctta gaaagttctg acagcggaga
     4501 attttattta gacggtgtac cgttcaaccc attcgagctt aaaatgaaag aacaagttgt
     4561 aggagtcgta ttccaagact tccagctatt tccacatctg aatatttttg aaaacattac
     4621 cttagcacca aaaatggtat tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga
     4681 attagcggct tcattaggga ttagtgattt attgaatatc tatccttatc agctttctgg
     4741 cggacaaaaa cagcgggtag cgattgccag agcattggct atgaatccac gggtattggc
     4801 ttatgatgaa ccaacaagtg ctttagatcc tgaattacgc cagcaagtcg agcgtttgat
     4861 cctatcattg aaagaagatg gggtaaccca aattattgtc acccatgatt tagtatttgc
     4921 agaaaatgtc ggtgatcaat tactaaaagt ttccccaatt cattaagaaa ggagaagata
     4981 gagatgaaaa aaaccagttt tctattcgct ttgatcgcag gtcttcttct ttttgcaggc
     5041 tgttcgaaca aaaaaacttc agcagataat tgggcgacta tcaacgaaga gaaaaaaatc
     5101 gttataggtt tagacgatac atttgttcct atgggattta gagataaaga cgggaagctc
     5161 acaggatttg atattgattt agccaaagca gtctttgaac aatatgggat tacggtagac
     5221 tttcagccca ttgactggtc aatgaaggaa tttgaactga acaatggaac gatcgatttg
     5281 atatggaacg gctattccaa aacgccggca agagaaaaga aagtgcaatt tacaaaacct
     5341 tatatggaaa acgatcaagt gctgatcaca cctaaagaat caggaatcac aaactttgga
     5401 caaatgaata ataagagatt aggtgcgcaa aatgggtcat ctggttatga tgtatttacg
     5461 aaacaaccag aagtattaaa agagatagtc aaaaaccaag atgctgtttt gtatgatagt
     5521 tttaatgaag cattgatcga tctgaaaagc agacgggtcg atggtctgct gatggataaa
     5581 gtatacgcag actattattt gaaacaaaga aacgaactag aagacttcaa cataacaaaa
     5641 ggttcttatg agagtgagga ttttgcagtt ggtgcacgca agtcagatag tacattagtg
     5701 aaaaaaatca atgaagccct agatcaacta gagaaaacag gtgaattcca aaaaatatcc
     5761 gataaatggt ttggcgaaga tgttacgccg agaaattaac aaatagggga ctgtgacaaa
     5821 agacgtgtca cagtcccttt ttccgaataa acagtgttct cctgccaact ccttgtgact
     5881 cggagctgaa tggcaggctc acaacctctt ggtaaacggt gttcaaaagc cagtttttcg
     5941 gtattaagcc aaatttatgc aaaaatgtag aaagccattt tcacaaaatt tttcttacta
     6001 ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg ttgtggaagg
     6061 ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa gagatgaatg
     6121 gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc ttctgcagcg
     6181 tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg ggatcgattt
     6241 gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt agaccactat
     6301 catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc
     6361 tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca agctgggctc
     6421 gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc tatgttgact
     6481 ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg ggaatcacgt
     6541 cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt ccgcgggaaa
     6601 gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg ttatttgtta
     6661 gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa ccatattgct
     6721 aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc tggaaaaatc
     6781 ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga aaatgttctg
     6841 gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta tatgtgggga
     6901 aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc aacgattgaa
     6961 gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat caattactat
     7021 caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa aatgaatacg
     7081 acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa aaaagttgag
     7141 aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg attaaggatc
     7201 ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga aaatggctta
     7261 ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg aatcaattac
     7321 ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga agtcctaggc
     7381 tattgcacct ggtcttatac agatttgctt agctggctga acggttatca aaagcgatat
     7441 ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg atataagaaa
     7501 gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct ttagttcaca
     7561 tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata aaatcattta
     7621 gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag ttctttcaaa
     7681 caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat gagggataat
     7741 aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc
     7801 aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg attttatttg
     7861 ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac ggctttcgga
     7921 tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta ggattttgga
     7981 ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt ggcggcatac
     8041 tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa ctccatactg
     8101 gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata aaacaaagtc
     8161 aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat tttacttact
     8221 tcttgattgc acagcctgga agttatttag cagcagtgct attactggca ggaggagcat
     8281 tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca attggagaac
     8341 gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg
     8401 aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct gcaaaagaag
     8461 ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag caaagggaaa
     8521 atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta agttttgttc
     8581 caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca gtaccagata
     8641 caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag gatgacggta
     8701 cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa ttaccgacag
     8761 ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa
     8821 aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca
     8881 aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag
     8941 taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg aaagatgtcc
     9001 ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca aatggaaaga
     9061 tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca gataaattac
     9121 tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat ctttcgaaga
     9181 tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca attaatggga
     9241 ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg atgatcgatc
     9301 cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg ccggtcgtga
     9361 cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg gaagaacgat
     9421 atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa tttgttcaac
     9481 agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta gtgatcgtag
     9541 atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg attattcgtt
     9601 tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa cgtccaagtg
     9661 tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca tttgcggtat
     9721 caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag ctcttagggc
     9781 gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg caaggagcat
     9841 tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag caagaagctc
     9901 attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct ccagaacagc
     9961 cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta
    10021 tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt ttagtagatg
    10081 aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg aaagtattca
    10141 ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg
    10201 atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata ccaaaagaaa
    10261 aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg
    10321 agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg aatcatgtat
    10381 agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca gtccatttat
    10441 ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa aaaattccga
    10501 gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg
    10561 aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa
    10621 cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga actccctgat
    10681 aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt ttgtgtgacg
    10741 acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac
    10801 cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca ttattttgat
    10861 gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg tgagccattt
    10921 gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa aggattggca
    10981 attggtgctc ggcacattac agtttccact agtggattag cacacaaaat caaggaattc
    11041 gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa taatgaggtg
    11101 cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat ggaagctgtg
    11161 gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat gttgaatcaa
    11221 gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa
    11281 ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca atattctcgc
    11341 agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg cgtaaactgt
    11401 gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt gcgaagcaag
    11461 caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa ttaccataaa
    11521 aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag attctatagc
    11581 gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa atgtcctcaa
    11641 tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt tcttatatcc
    11701 ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct gtttaaattt
    11761 ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg ctttatctaa
    11821 gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata ctggaagttg
    11881 gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat ccatcatcaa
    11941 taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca ttttttctag
    12001 aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat tgttaactaa
    12061 aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa ttgcatatga
    12121 gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga gacgatcaat
    12181 gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat cgccacgagc
    12241 agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc ataagtattt
    12301 atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg gttttgaagg
    12361 aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg cagtgacggg
    12421 cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt tttcaccaat
    12481 gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt ctgctttttg
    12541 gacactttca tgctggatca actgttcaat atttccataa gttgaattac ccccgtacca
    12601 gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt tttctgcctt
    12661 tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt tgacgattcc
    12721 atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa cactttgact
    12781 catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag tgatcgatct
    12841 gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat gaataaggtg
    12901 gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac aaaaacattg
    12961 aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc tttgcttttt
    13021 tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt tttatttgtc
    13081 aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga acaaacagag
    13141 ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag tgtttctgta
    13201 taattttttt attttataag taagataaat aatgaaagaa tagagatact gattggtagc
    13261 taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa taagcaagaa
    13321 caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt attgaaagat
    13381 cagctttctg atttactgag actgacttgg ccggaagaat atggagacag ctcggcagaa
    13441 gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga ccaagatgag
    13501 ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga attgcatcca
    13561 ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt caattactta
    13621 gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga tgatttagac
    13681 catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa agtggcttcc
    13741 atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta taaaatcgta
    13801 ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc aaaaacgatt
    13861 attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat cagcttcaag
    13921 aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc aacttatttc
    13981 cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg cttagtttcg
    14041 agtagtaaga aaaattttgt gaaaatggct ttctacattt ttgcataaat ttggcttaat
    14101 accgagaaac tggcttttga acaccgttta ttcagataag ggactgtgac aagacttttg
    14161 tcacagtttc tttttgttta ttctttttta tctttgtatg gcaataatag acaatataac
    14221 gaaaattatt taatggcttt tggaagacca tggaaaacct tgtacaaagc tattttttct
    14281 gaaaaattcc ttgaaacctc acgaaaaaat cattatttta tgaaaaagac aaaaaaaagt
    14341 gttgattttt taataattat tcattaaact cttaaacaac ttcagaaaat attaattatt
    14401 ctgaaaattc caataaaggg gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg
    14461 cggtatgcgg ccttgtactt gctggatgtt atggcggcag ttcagccaca agcagtagtt
    14521 cagcaaaaag cggttcagca gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa
    14581 tgcctacagc tgacttatca gttgcaacag atacaatcag ttttacagca ttgaataacg
    14641 tttatgaagg aatttaccgt cttgatgaag acagcaaacc acagccggca ggagctagcg
    14701 agttggcaga agtcagtgaa gacggattaa cttacaaaat caaattacga gaagacgcaa
    14761 aatggtcaaa tggtgatcct gttacagcag cggattacgt ttatggctgg caacgaacag
    14821 tagacccagc tacagcttct gaatatgctt acctgtatgc gccagttgaa aatgcagaag
    14881 acattacagc tggaaagaaa gataaatcag aactagggat caaagcagtt ggtgactatg
    14941 aattagaaat caaattgacg aaacaaacac catatttcca atatctgctt gctttcccat
    15001 catttttccc acaaaaacaa tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa
    15061 gtgataaagc tgtttataat ggaccattca cattagaaga ttttgatgga ccaggaacag
    15121 atacagaatg gacttataag aaaaatgatc attactggga caaagataca gtaaaacttt
    15181 ctgaaatcaa agtcagtgta gtaaaagaat cttctactgc attgaactta ttcaaagatg
    15241 gccaagcaga tgacgtgatc ttgtctggtg agttagcaca gcaaaacgca aacgatccag
    15301 cttatacttc tgttaaagaa gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga
    15361 attcaccatt caacaatgtg aacctaagaa aagctatttc ttattctatc gatcgtgaag
    15421 ctttagtaaa acaagtacta ggtgacggat cagttgtctc tacaggattg atcccatcag
    15481 atatggtaaa aagtccaaca acgaacgaag actttgcaaa agaagctgga aaattagttt
    15541 cttatgacaa agataaagca aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg
    15601 attctttaga atttgatttg atggcttctg atgatgattc atcgaaaaaa gtaatcgaat
    15661 atgttcaaaa ctcaatccaa gaaaacttgg atggcgtaac agtcaaacca acacctgttc
    15721 cattctctgt acgtcttgac cgctcaactt cgggtgattt tgacgcagta ctaggcggat
    15781 gggctgctga ctatgcagac ccaagcagct ttactgattt gtttgtcaca ggtaattcat
    15841 acaaccgtgg tcgctggagc aatgcagaat atgacgaagc agttaaagca gcttcatcaa
    15901 cagacgctgg cgatgaacaa gcccgttggg atgatttcca aaaagcaatc aagatcatct
    15961 ctgatgatat gggtgtcgtt ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa
    16021 aaatcaaagg tatcgttcac catgcggcag gcgcttcatg ggattacaaa tggacatacg
    16081 ttgaagaata atcgttaata ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc
    16141 aacctcgttc tcatattcac ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga
    16201 gcaattagta ttccggcaat gatcagccaa aagctgtaca taccgtagct ggcagacgag
    16261 agcgaggaaa attctggttt tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc
    16321 tgaaaatgat cgaagaaacc cgaagaaaag acccataaaa aaccgccgat aatcagaaac
    16381 ggcaatgacc ataagaatag atcattagat aattgaatga gtgtaaagga atggttgatg
    16441 agatttttta ttaaaataac cagaatcagt agaaaagcta ctgcgtaggg gatagatttt
    16501 tttttcattt gattgctcct ttatttttgg ttcattatct aataatgtag cgaaacatct
    16561 gtcagaagtc aaaagctagg gggaaacatt agtgaatagt tatatcaaat atgtattaaa
    16621 acgtgtcttt ttcatgatca tcacgctttg gttaattgca acaatcacct ttttcttgat
    16681 gcaattgctg ccgggcacgc catatacgaa tcaggaacgt ttgagtcctg aaacaatcga
    16741 gatgctaaat aaacaagtcg gtttggataa accagttatc gtacaatatg ggatttatct
    16801 ttctaatttg cttcaaggag attttggaat ttccttccaa tttaaaaacc agccagtcgc
    16861 acatttgtta gctggaagaa tcggaccatc cttgcagtta gggttacagg caattatctt
    16921 tggaacagtc ctagggacga ttttaggaac gatctctgcc atgaagcaaa atacatgggc
    16981 agatacatct tctacactcg tagcgatatt aggtcgttcc attccaaact ttgtatttgc
    17041 tgttttatta caatatatct ttgcaatcaa attacaagtt ttgccaatcg caaaatggga
    17101 tggctttgtg tacacaatct taccaacaat tgcgttggcc atgtcgccgc ttgctgactc
    17161 tgctcggttt atccgtacgg aaatggtgga agtactgcat agtgattatg tggaattagc
    17221 aaaagcaaaa ggattgagcc gttgggaaat cgcctttaaa catggtcttc gaaatagttt
    17281 gattccattg atgactttat taggaccgtt agctgtagca ttgatgaccg gatcactggt
    17341 ggtagaaaat atctttgcta ttcctggtat cggggaacaa ttcgttaagt caatcacaac
    17401 aaatgattat cctacgatca tggctgtaac gatcctttac tcatttatgc tgatttttgt
    17461 tattttgatc gtggatctat tgtacggtct agttgatcca agaattcgtg tttcagaagg
    17521 gagccgagga taaatggaaa tgataccaaa gcgttatgaa acagttgcag atatccctgc
    17581 ggatgaattt cttccattac aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc
    17641 ttctttgaat tttatccaag attcatggcg ccgtttaaag aaaaacaaag ctgccgttat
    17701 ttcaatggtt ttactattgg tcatcatttt gatctctgtg atcacaatct ttgtttctcc
    17761 tcatgatcca actgcccaaa acgtggctta tatcaatttg cctcctcgta ttccgggaat
    17821 caatatcgat ggattgaatg gaaaagcaat ggttggtggt gaacttgttg ataaatatgc
    17881 tcaagcaaac gtcccttcaa acgtaaattt ctttttagga acagacggtt tgggacgtga
    17941 tgtattaagc cgcttattta tgggaatgag aatctcgttg ctgatcgcat ttattgctgc
    18001 attactagat gtaacgattg gtgtagctta cgggttggtt tctggtttgt taggcggacg
    18061 tgtcgataac gtgatgcaac gttttttgga aatcttatca ggaattccaa acctcgttgt
    18121 catgattttg atgttggtcg tttttgaacc aggaattttt tcaatcgtgg ctgctatggc
    18181 catcacaaac tggataccaa tggcacgtat cgttcgtgca caaacaatga aattaaaaga
    18241 tcaagaatat gttttagctg gattgacatt aggtgaatca agaatgaaaa ttgcattcaa
    18301 acatattttg ccgaatatct ctagtgtcat tattattcaa atgatgttta gtattccatc
    18361 tgctattttc ttcgaagcct ttttaagctt tatcggttta ggtcttacgc ctccgtcagc
    18421 ttcattagga acgatgttga gcgaagggta caagacattc ctgtatctgc cttatctatt
    18481 atggattccg gcagtaactt tatcggttat catgattggc tttaacttac ttgctgatgg
    18541 attgcgtgat gcctttgatc ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa
    18601 gtgaaagact tagaaatctc ttttgatacg tatgctggaa aggtacgagc gattcgcggt
    18661 gtcaattttc atttgaataa aggagaaaca ttggcgatcg ttggggaatc tggaagtgga
    18721 aaatcagtga cgaccagaag catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct
    18781 ggtcaaatcc tctttaaagg taacgatatc gttggaaaat cagaaagaga gatgcaaaaa
    18841 atccgtggta aagaaatagc gatgattttc caagatccaa tgacctcttt agatccgacg
    18901 atgcccattg ggaagcaagt cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa
    18961 gagggacaaa aagctgcatt agaattgctt aaattagttg gaatacccga agctgagaaa
    19021 cgtatcaaca gttatccgca tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg
    19081 attgcactgg tatgttatcc ggaaatcctg attgctgatg aacctacaac agcgcttgat
    19141 gtgactattc aagcacagat tttggagctg ctgaaagaaa ttcagacaaa aatcgataca
    19201 tcaattatct ttatcactca tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct
    19261 gtcatgtatg gaggaagaat cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg
    19321 caacatccct atacttgggg actgcttggt tcaatgccga cattagatag tgcgaacgat
    19381 cgattgtatg ctattcctgg ttctccaccg gatttattga acccgccaaa aggagacgca
    19441 ttctatccaa gaaatgaatt cgcgatgaaa atcgatgcag aacaagaacc accatttttt
    19501 gaactatcaa aaacacacaa ggcagcaact tggctacttg ctccgcaggc acccaaagtg
    19561 acaccgccag aagaaatcca acgtcgctgg gctatcttta aagagaaaca aaaacatact
    19621 tacggtcaag gaggaattgc tgatgccaaa taaactactt gaagttaaag gattgaaaca
    19681 gtatttcaat gtaggaaaaa agaatgaagt acatgctgta aatgacatca gctttcacat
    19741 ttatgaagga gaaacattcg gtttagttgg agaatctgga agcggaaaat ccactactgg
    19801 ccgtacgatc attcgcttga atgaacctac tgatggtgag atattattcg acggtcaaga
    19861 tataacgaag atcaaagata aaaaaggttt gacgaaattc cggcatgatg ttcagatgat
    19921 ctttcaagat ccatacgctt cgttgaatcc tcgtatgaaa gtcagagata tcattgccga
    19981 aggaattgat gttaatggac tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga
    20041 tctattgaga actgttggat tgaatccaag ccacggtact cgttatcctc atgaattttc
    20101 aggtgggcaa cgccagcgta ttggtattgc acgagcattg gcagtaaaac cgcgttttat
    20161 catttgtgat gaaccaattt ctgcactaga tgtgtcgatc caagcccaag tggtcaattt
    20221 gttgcaagat ctccaaaaag aacatcaatt gacctatcta tttattgcac atgatttgtc
    20281 gatggttaaa catattagtg accgaatcgg tgtaatgcat aacggcttgt tattagagat
    20341 gggaacaagt gatgaaatct ataatcacgg tgttcatcct tatacagaaa gtttgttatc
    20401 tgctattcct ctaccagatc cagaccatga gagaaaacgc agaagaatca aatatcaacc
    20461 tgaaccagat gacggacaag tacgtcaact tcgtgaaatc gcaccagaac attttgtcta
    20521 tgcaactgag caggaagtcc catattacgc aaaaaaacta aaacgacaaa aggaatctct
    20581 tctggttgct aactaggagg gacatagatg ctaaaagctt ttaaattccg tatgtatccg
    20641 acagaagaac aaaaacagca attgattcgt acttttggat gtgctcgatt tacctataac
    20701 catttgctga aaaagcggca gaaaagttgg caacaaacag gagtagccaa tttttcgctc
    20761 acacccgcta cattaaaaaa agaataccca ttcttaaaag aagtagacag tcttgcttta
    20821 gcaaatgcac agcttaattt ggatcgggct tttcgcaatt atttcaaggg acgtgccagc
    20881 ttcccaaagc ttaaaacgaa aaaaagtatg tggcaatctt atacgaccaa caaccaaacc
    20941 cgtacgatct atctggaaaa tggctactta aagttaccaa aacaaaaaga actaatcaag
    21001 ataaatcagc atcggccagt tgaaggatcg attcgctccg ctacgatttc tgctcgatat
    21061 aatgaagaat tttatgtcgc actactttgt gatgtttcgc cagtaaaaaa agaatcttta
    21121 gctaaatgga tcgggatcgc ctatcatccg aagacattga tccaaacatc tcgacctcta
    21181 gaagtaactt taccaaaatt tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa
    21241 ttgaatgtga aagtccgctc cgctcaccat agaaagatca ggttagatca ggcaagcaat
    21301 tatcagaaac aaaagagaaa agtaatggat ctttatctga aacaaaagaa ccagcgagaa
    21361 gattatcttg aacaattatc tgggaaattg gtcaaacaat atgactactt atttgtagaa
    21421 tcttttccaa aagaagaggc acatgctgat ttttctattc acgactggca taaattaata
    21481 acaaaattgc gttataagtc ccaatggtat aataaaaaat ttcttttgat caataccgac
    21541 ggagcagaag aaagcaattc cgtaagaaag agccaagtag tagaaaaaat gggcagacat
    21601 tcggttatca agggataaaa aatgaatgaa actgatagga gcgttagggt tagccttgtt
    21661 aataaaaagt cttaatgact tttgtttcta ggaatttttc ttttgaagaa aagctcacta
    21721 attatgacaa accaataaaa
//
LOCUS       DAIGQM010000051        21282 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.051, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000051 DAIGQM010000000
VERSION     DAIGQM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.051"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            133..507
                     /locus_tag="NOA48_001924"
     CDS             133..507
                     /locus_tag="NOA48_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0790180.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="NOA48_001925"
     CDS             complement(621..1250)
                     /locus_tag="NOA48_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0790181.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="NOA48_001926"
     tRNA            complement(1384..1456)
                     /locus_tag="NOA48_001926"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="NOA48_001927"
     tRNA            1670..1743
                     /locus_tag="NOA48_001927"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="NOA48_001928"
     CDS             complement(1881..2045)
                     /locus_tag="NOA48_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790182.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="NOA48_001929"
     CDS             2340..3668
                     /locus_tag="NOA48_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCI0790183.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="NOA48_001930"
     CDS             3870..4703
                     /locus_tag="NOA48_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCI0790184.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="NOA48_001931"
     CDS             4719..5456
                     /locus_tag="NOA48_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCI0790185.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="NOA48_001932"
     CDS             complement(5611..6579)
                     /locus_tag="NOA48_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCI0790186.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="NOA48_001933"
     CDS             6811..7644
                     /locus_tag="NOA48_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCI0790187.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="NOA48_001934"
     CDS             7678..8517
                     /locus_tag="NOA48_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0790188.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDCYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="NOA48_001935"
     CDS             8543..9103
                     /locus_tag="NOA48_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0790189.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="NOA48_001936"
     CDS             9302..11023
                     /locus_tag="NOA48_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCI0790190.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="NOA48_001937"
     CDS             11188..12330
                     /locus_tag="NOA48_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0790191.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="NOA48_001938"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="NOA48_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCI0790192.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="NOA48_001939"
     CDS             14130..14777
                     /locus_tag="NOA48_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0790193.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="NOA48_001940"
     CDS             15170..17815
                     /locus_tag="NOA48_001940"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCI0790194.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="NOA48_001941"
     CDS             18125..19438
                     /locus_tag="NOA48_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCI0790195.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVITGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="NOA48_001942"
     CDS             19428..20081
                     /locus_tag="NOA48_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0790196.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="NOA48_001943"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="NOA48_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI0790197.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="NOA48_001944"
     CDS             20978..21178
                     /locus_tag="NOA48_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0790198.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7185 a         3550 c         4445 g         6102 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gattgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtaa taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg ta
//
LOCUS       DAIGQM010000052        21241 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.052, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000052 DAIGQM010000000
VERSION     DAIGQM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.052"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(132..509)
                     /locus_tag="NOA48_001945"
     CDS             complement(132..509)
                     /locus_tag="NOA48_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790199.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="NOA48_001946"
     CDS             765..1493
                     /locus_tag="NOA48_001946"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCI0790200.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="NOA48_001947"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="NOA48_001947"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCI0790201.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="NOA48_001948"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="NOA48_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCI0790202.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="NOA48_001949"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="NOA48_001949"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCI0790203.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="NOA48_001950"
     CDS             4628..6067
                     /locus_tag="NOA48_001950"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCI0790204.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6090..7142
                     /locus_tag="NOA48_001951"
     CDS             6090..7142
                     /locus_tag="NOA48_001951"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCI0790205.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="NOA48_001952"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="NOA48_001952"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCI0790206.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="NOA48_001953"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="NOA48_001953"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCI0790207.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="NOA48_001954"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="NOA48_001954"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCI0790208.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="NOA48_001955"
     CDS             10661..11575
                     /locus_tag="NOA48_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0790209.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="NOA48_001956"
     CDS             complement(11708..13273)
                     /locus_tag="NOA48_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0790210.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="NOA48_001957"
     CDS             complement(13266..14717)
                     /locus_tag="NOA48_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0790211.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="NOA48_001958"
     CDS             complement(14731..15747)
                     /locus_tag="NOA48_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0790212.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="NOA48_001959"
     CDS             15967..17055
                     /locus_tag="NOA48_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCI0790213.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="NOA48_001960"
     CDS             17109..18635
                     /locus_tag="NOA48_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCI0790214.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="NOA48_001961"
     CDS             18637..19842
                     /locus_tag="NOA48_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0790215.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="NOA48_001962"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="NOA48_001962"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCI0790216.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6810 a         3594 c         4822 g         6015 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcg
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 t
//
LOCUS       DAIGQM010000053        21100 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.053, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000053 DAIGQM010000000
VERSION     DAIGQM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.053"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            155..1861
                     /gene="efbA"
                     /locus_tag="NOA48_001963"
     CDS             155..1861
                     /gene="efbA"
                     /locus_tag="NOA48_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCI0790217.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2019..2921)
                     /locus_tag="NOA48_001964"
     CDS             complement(2019..2921)
                     /locus_tag="NOA48_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0790218.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2918..3610)
                     /locus_tag="NOA48_001965"
     CDS             complement(2918..3610)
                     /locus_tag="NOA48_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCI0790219.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3653..4294)
                     /locus_tag="NOA48_001966"
     CDS             complement(3653..4294)
                     /locus_tag="NOA48_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0790220.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4332..4646)
                     /locus_tag="NOA48_001967"
     CDS             complement(4332..4646)
                     /locus_tag="NOA48_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790221.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4634..5986)
                     /locus_tag="NOA48_001968"
                     /pseudo
     CDS             complement(4634..5986)
                     /locus_tag="NOA48_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5983..6915)
                     /locus_tag="NOA48_001969"
     CDS             complement(5983..6915)
                     /locus_tag="NOA48_001969"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCI0790222.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6912..7688)
                     /locus_tag="NOA48_001970"
     CDS             complement(6912..7688)
                     /locus_tag="NOA48_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCI0790223.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7742..10927)
                     /gene="carB"
                     /locus_tag="NOA48_001971"
     CDS             complement(7742..10927)
                     /gene="carB"
                     /locus_tag="NOA48_001971"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCI0790224.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10932..12008)
                     /gene="carA"
                     /locus_tag="NOA48_001972"
     CDS             complement(10932..12008)
                     /gene="carA"
                     /locus_tag="NOA48_001972"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCI0790225.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12013..13293)
                     /locus_tag="NOA48_001973"
     CDS             complement(12013..13293)
                     /locus_tag="NOA48_001973"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCI0790226.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13312..14238)
                     /locus_tag="NOA48_001974"
     CDS             complement(13312..14238)
                     /locus_tag="NOA48_001974"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCI0790227.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14251..15534)
                     /locus_tag="NOA48_001975"
     CDS             complement(14251..15534)
                     /locus_tag="NOA48_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCI0790228.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="NOA48_001976"
     CDS             complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="NOA48_001976"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCI0790229.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16322..17233)
                     /locus_tag="NOA48_001977"
     CDS             complement(16322..17233)
                     /locus_tag="NOA48_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0790230.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17230..17694)
                     /locus_tag="NOA48_001978"
     CDS             complement(17230..17694)
                     /locus_tag="NOA48_001978"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCI0790231.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17699..18397)
                     /locus_tag="NOA48_001979"
     CDS             complement(17699..18397)
                     /locus_tag="NOA48_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0790232.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18384..18770)
                     /locus_tag="NOA48_001980"
     CDS             complement(18384..18770)
                     /locus_tag="NOA48_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790233.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18917..20587)
                     /locus_tag="NOA48_001981"
     CDS             complement(18917..20587)
                     /locus_tag="NOA48_001981"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCI0790234.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20770..21003
                     /locus_tag="NOA48_001982"
     CDS             20770..21003
                     /locus_tag="NOA48_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCI0790235.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
BASE COUNT         5901 a         4747 c         3743 g         6709 t
ORIGIN      
        1 cctaaaaatt tggatttcaa cgatagaaac actgtttttt atgtaattag tccaagattt
       61 ttctagactt ttgctttact attcggccaa attggttttt cttctttttt tcgttataat
      121 gaatatactt atgaaaagaa atgaggaatg aaccatgtcc tttgatggtg tatttaccca
      181 cgcgatggtc aacgaattgc gtgaaacgtt actatctggc cggatctcga aaatccatca
      241 gccttatgaa aatgaaatcg tgctggtgat tcgttcacgc ggcaaaaacc atcgattatt
      301 attatctgcg cacccaagtt atgctcgtgt acagattacc caaatcgatt atcagaatcc
      361 tgataatccg cctaacttcg tgatgatgct tcgaaaatat ttggatggcg ctattttaga
      421 agacatcgaa caaatcgaaa atgatcgagt gatccatttc cactttgcta aacgaaacga
      481 gttgggtgat ctacaaaata tcatattgat cgttgaatta atgggacgtc atagtacgat
      541 cgtcttagtt aatcgagaaa ctggaaaaat actggatgcg atcaaacaca ttggaagctc
      601 tcaaaacact tatcgttctt tgcttcctgg tgtagaatat gttgctccgc caaaacaaga
      661 ggtcttgaac ccatttagct ccgagaaaga aaaaatcttt cagcggcttt cccaaactga
      721 actagatcca aaagcaatcc aacgtcagtt tcagggaatc ggtttcgata tcgctcaaga
      781 gctgaccaaa agattactgg aacgtcctaa tgaaaagatg gttgtatggg acgaattttt
      841 ctcagccatc agccatcagc ctattcctac tttttacgaa acggaaaata aagatttttt
      901 cacaccgatt gcttatcagg tattgtccga acaggcatct gctgtaacag cttatccaac
      961 actcagtcaa ttattagata gctattatca cgaaaaagca gagaaagatc gggcaaaaca
     1021 acaaggcgga gaactgattc gaaaaatcga aaatgaacta aaacgaaata aaaataaatt
     1081 gaaaaaacgt gaacaaacac tcaaagaatc cgaaaacgct gagaattacc gtagaaatgg
     1141 cgaactactt actacttttc tgacacaagt accacgcggc gcaaaagaag ttgttttacc
     1201 taattattat gaagaagatc ggccaatcaa aatagcacta gatccggcat tgacaccaaa
     1261 tcaaaatgca cagaaatatt tccatcgata ccaaaagctg aagaacgctg ttaagctgat
     1321 tggcgaacaa atccaagaag ccaaagatga aatccaatat cttgaatctg tcttatctca
     1381 actggaaatt gccggcccaa tggatatcga agcaattaaa gaagaattga cttcagaagg
     1441 atacctgaaa aagaagaact taaaaaaaca aaaacgtaag aaaccatctc agcctgatca
     1501 atacttttct tctgacggaa cgctcattct tgttggtaaa aacaatcttc aaaatgacca
     1561 gctgacaatg aagacagcta aaaaaaccga ctattggctt catgcaaaaa atatacccgg
     1621 ttcgcacgtc atcattaaaa gtgacaagcc ctcagatgaa acaattacag aagctgccga
     1681 gttagctgcc tatttttcaa aataccgata ctctgcccaa gtgccggttg atcttgtaca
     1741 ggtaaagcat atccgaaaac caaatggcgc caagcctggt tatgttattt atgaaaacca
     1801 aaagacgatt atcgtgacac cagaagaaga aaaaattaca gctatgaaac aaaacaggta
     1861 atcaatgagt gtttctagaa tcatatttgc gtactttccc acaacagcaa ttagttataa
     1921 attgtttgct acaaaaagag gagttgtgac aaaattctgt cacaacccct cttttttgat
     1981 caacggtgtt caataaacag cgttctcatc tgcttttctt agctctgctg gtccagtaac
     2041 cgagtaagct ctttgataaa tctttgagcg atttcactga gcggacgttt cgccgaataa
     2101 atgatataaa attcatttag ttcgccttct gccaaaggga ttaaccgcaa gtgctcgcga
     2161 atccctccaa tcacaatacc agatcctgaa gcgtaagcat cagtttcaag aacgatattc
     2221 atcaaagtac ctcgatcact cgtataaatc actgtttctt gatcagggat ctcgataagg
     2281 tcttcataaa aatacgggaa attatttcca tcctgtgtaa aacgaacttg aggataagat
     2341 aacaattctt ctttggtgat ctctgcgtgt tcagctaatg gatgtccttg ccttaaaaaa
     2401 atatgcgttt tgaattttcc aatgctgcgg ccacttagct ctccttgttg taaatatctt
     2461 ctgataccag cttgattatg ctcattcata taaataatgc cgatctcact gtgctgctct
     2521 ttgacttctt cgatcactct cgctgttgtc gtctccatga tccgaaattg tttgatctcg
     2581 tctttgaatt cctcgagtag ctgtgcggtc aaaggaccta agaaatcata atgctgggca
     2641 gcgatcgaaa aattgtctct cttttcactc gttagatagt gagtttctaa tgtatcaagc
     2701 tggaccaata ttttctcggc acgatttaag aagtcttgcc cttcttctgt taaatatgcc
     2761 cctcgattcg ttcgagtaaa cagcgtgatc cctaactcgg tttctaattc tttgatacca
     2821 gctgaaagac ttggctggga gacaaacatt ttctttgccg cttctctgaa actaccattg
     2881 tttgctacag cgaccacgta tttcatctgc tgaatattca ttgctcaaac tcctcgaaat
     2941 aataaatttc tcttccattc aagggctgga ttggtcggtt gttcggtcga gcatactgac
     3001 catcgaaggg gagaagaaac tcttggttca gttttcctac atgatccatt acaaaccatt
     3061 ggattggccc gctggtaggc ggagttgtca atgagccaat ataatggaaa tggctttttt
     3121 gctccggaaa gaacacatcc ggatttaccc aatgctcatg tttttctaag ttccaacttt
     3181 ccccattttc ttgattatac agccaacctt cctgtaccat tagctggtac atgacaccca
     3241 caactagatt ctcttttttg ctgttcatat gaacaaaatg aaattcaata tcttcctgtt
     3301 ttccgttgat gatatgttca gaaggcaagt ggaaatgaat atctgtcaaa taatagcgtt
     3361 ctttcttgaa ctctacataa ctgagttggt caaaaggtac taaatgaatc gtgtttttga
     3421 attccttgtc agtaaaccgt tgcttttgat aatgaaagga aagcgtgtct ccttctattt
     3481 tggtttcttc ccccttggtc aaatgaatag gcgactgcaa tggaaattcc gcacctctcg
     3541 caaaccaatc acataaactc gcccaatttt ccggaccttt gtctccagaa tagccccatt
     3601 cgacatccat attctttttc aactatactt ccccctgcat ctcatatcat ttttattttt
     3661 cttctttctt tacaatcgtt gagacggttt ctaaaaacgc ctcttttcca taaaattcct
     3721 ggttcaatag ttccggaaat atctctttaa agaaatactg aacagaaggc cgatgttcaa
     3781 agcttttaat cgtagtcact gcctcaatga acatctcctt ataaactttt tccgggttat
     3841 ttttgatgat ttcatcaaaa gattcataaa gaaggtcaac cttatctgaa atggctaata
     3901 gttctccttc tacggtttca tcttttcctt cgaacaaccg acggcgataa acttcttgga
     3961 actcagctgg aatctcttgg ttgatgaatt cgtccgtcat cttttcttca actgtttgca
     4021 gcatccctct taactctttg cttgcgtatt tcaccggcgt tttgatatca ccaataaaac
     4081 gctctgtgta gtcatgattc aatgattttt catagagcag tttccaatcg atcggttgtc
     4141 cattcgcttc ttcaatgtct cctagaactt gcgcaataga tgctacacga tacgaatgtg
     4201 ctgcaactgt atgctctgta tatttaaaaa atccaggtgc ccttgtgatc gtctctaaat
     4261 tgttcaatcc taaaataaat tcattcaacc ccataaaagt tacctccctt tgagatttct
     4321 ttttccgaat atcatatcat taaataactg atattcgcaa catttccgct ctttaccatt
     4381 tttgaaacag ctcccttacc aaaaaataga gaaaatctat atataataga aaaaagagaa
     4441 gagattattc tcttctttct gctaaccagt cttagaaaaa tgaattttaa aaaaatcaaa
     4501 aactgatcac gatagaagtt tcttttcata cctgatgaaa agatgcttct cgcaatcagt
     4561 ttttggattt ttgctattcc aattgatgat tctggagaca caaatcggat ttctctatct
     4621 tcatcaagcg cgcttaaatc tgccaatttt caggatcttt tttccattct tttagcagag
     4681 ttaattcttg ctcatcgata taacgatctt ctaaagctgc ttcaatcaat acagaataat
     4741 tggtcaacgt cataagaggg atttcggctt tttcgaaatt tgcttttcct tttggcaact
     4801 catacgtaaa gatagccgca acaccaagga tatccgcacc ttctcttttt gctgcttcag
     4861 ctgcttccaa gacacttccg cctgtagaaa tcaaatcctc gatcacaacc atcttctgac
     4921 cttcaaatat acgtccttcg atttggttac ctttcccatg atctttcgcc ttacttcgaa
     4981 tatagaccat tggcaaatcc agtatttccg ctacccatgc ggcatgaggg attcctgctg
     5041 ttgcagttcc agcaatcact tgtacttcag ggtaagcttc tttgattttg cttgctaatc
     5101 cttttgcgat ctcttttcgg acttttggat agctcatcgt gattcggtta tcacagtaaa
     5161 ttgggctttt gattccactt gcccatgtaa aaggattact tggatttaaa aatactgctt
     5221 caatttctaa taagtctttt gcgatacttt gttcaacatt cattttaggt tagctccatt
     5281 ctgtttgaat cgtttgatat gctttataag gattagttga ctgagtgatt ggtcgaccta
     5341 taacgataaa agttgagccg atcttttttg cctgagaagg tgtgactact cttgtctgat
     5401 ctcctgcgac tgttccttct ggtcttatac ccggagttaa gcaaacaaat tcgtctcctg
     5461 ccatttcttt gatcgcttct acttcccaag cagaagaaac cacaccatct aatcctgctt
     5521 ttttggcaca gctagcataa tggatcacac ttttttctaa agaaacttcg attagttgat
     5581 cggcatgcat ttcttcttca cttgtagaag taagctgagt gatagctaga agtagcggac
     5641 gttttccacc ttctggagtc ccctcttcta atcctcgcat tgccgcctcc atcatacgaa
     5701 taccgccagc ggcatgaaca caggtgagat caacaccaag ctttgccaat ccccgcattg
     5761 ctttttcgac cgtattcgga atatcgtgaa gtttcagatc taaaaataca ttatgaccag
     5821 cctcttttag ataacgtacg atttcaggtc cttcttggta gaacaattcc attccgattt
     5881 tcacaaacaa tttttcttct ttcgggaaaa atcgaagaaa gtcttctacc tcttgcctag
     5941 ttgaaaaatc taatgcaata attggtcgtt ggtctagttg attcatcgtt cacgttcctc
     6001 tctcacttct ttgattaatc tttccagcga ttcgatgcct agttcgctca ttcgcacagg
     6061 gagctcttta attagtttag gacagatata cggatcggtg aaattcgcgg tccctatagc
     6121 tacagcactt gctccagcca taaacatctc aagaacatca tccactgtct gcacgccgcc
     6181 catcccaatg attggaaggc tggatatact tgctacttgg tgaatcaaac gaatagcgac
     6241 aggcttgatt gctggtccgg agagtccacc tgtttgattg gctaaaatcg gttttcttgt
     6301 cttaaggtca atccgcatac caagaagagt attgatcatc gtaaacccat ctgcccctcc
     6361 agcttcgatt gcctgagcga ttggaacgat gtctgttaca tttggggaca atttgacata
     6421 gacaggaaca gaagaaactt tctttactgc ttgtgttaat tgaaaagcaa catcagaatc
     6481 tgttccaaaa gcaattccgc catgtttgac atttgggcaa gaaatgttca gctcgattgc
     6541 tttcacattt ggtgcttcgc caattttgct acaaacttct acatagtctt cttcacaagc
     6601 accagcaaca tttgcgatga tgggtaactc attgtactcc tctaattctg gaagaagttt
     6661 atgcataaca acgtctagac caggattttg caaaccaatt gcattcaaca tgccagatgg
     6721 tgtttccgcc actcttggcg tgggattgcc aaagcgggca tttggagtcg ttgccttgac
     6781 catgatcgat ccaagctgat tcaaatcata gtattttccg tattctttgc caaaaccgaa
     6841 acagccgctt gccggcatga taggattttt taattctagg ccaggaagtt tgaccgctaa
     6901 aggattctca ttcatataat tacctctcct attttaaaaa tcggtccttc gtcacaaact
     6961 ttcacacttt ttgttcctgt ttcatcttcc ggcgtatgac aaacgcaagc atagcaagcc
     7021 cctatcccac atgccatgcg ggattctaat gataactgga cattttgatg cgaagaaaac
     7081 agctgttcca ctgtcttcaa taacccgttt gaaccacatg caaaaacagc tgtaggttcc
     7141 gtcttcgttc ctaacaataa attaccgaca tttccgtgca taccgtatgt tccatcgtca
     7201 gtagcgattc ttgtttctcc tagacgatta aattcttttt cataataaac gacttcatgt
     7261 gtggcaaaac ctaaaaaatg cgttggctta attccttttt cgactaactg ttttgataac
     7321 tcatatagag gagggacacc gattcctcca ccgattataa atacttcgtc tcctgtatga
     7381 agattggaca aatcaaaacc attgcctaaa ggacccatga catctaaatg gtctccggca
     7441 gaaagagtag agaagactct agtcccctca ccttccaccc gataaatgat acggcaagta
     7501 tttgtttcgt ggtcgatatg attcaagcta atcggtcggc gtaatagcaa gtctgcacgc
     7561 ggcacgagaa tatgcaagaa ctgtcctggt tgctgcattt cttttactag atcacctttc
     7621 aatgtcattt caaaaatctt tggtgccagc tgtttttgct gaacgatttc catcatttct
     7681 tgtttcatct gtcccctcct gcaacggttt ttcgtctttt tgtcttaaca tgtgctcgcc
     7741 gttaaatagg gttagttgaa aaagcacggg attccatcac tcgaacgatc gcatctgctg
     7801 tgtctaaaga agtaaacaat ggaataccat gttcaactgc ttctcttcgg atgatgaaac
     7861 cgtctttaga agcatttccc cgatctttat caatcgtatt gacaaccact tgtgttttac
     7921 catctcttat taagtcgact acattttttt ctgctgcttc ctcagaaatt ttcgctactg
     7981 tttcaacgac cagaccattt ttttcgaaat aagcagctgt atgtttcgtt cctatcagac
     8041 tatagccaat ttctgtaaaa cgtttagcta attctagtgc ttcttctttt gtttcgtccg
     8101 caatcgtaaa taatacggct ccatattcag gcaagtgtaa tccagaagct tcgaatgcct
     8161 tgtacaaagc tttgtctaat tgtctgtcag atcccattac ttctccagtc gatttcattt
     8221 caggccctaa gtaagtatca actttctgca atttcgtaaa agaaaagaca ggtgctttaa
     8281 catgaacttc ttttgtttct ggataaagtc cgttttcata accaagtgtc tttagtttct
     8341 ctcccaaaat agctttcgtc gcaatttgtg ccattggaat tcctgtcacc ttacttaaga
     8401 atggaacagt ccgacttgct cgaggattga cttcgatcac ataaacctca ttttcatgga
     8461 tgacaaactg gatattcatc atcccgacac aattcaaacc taatgctaag cggatcgtgt
     8521 aatcttcgat cgttttcttg atcgattcag ataatgtttg aggtggatac acagccattg
     8581 aatcccctga atggacacca gcacgctcaa tatgctccat gatccctggg atgagtactg
     8641 tttcaccgtc acaaatcgca tccacttcgc attcaccacc aagcaagtaa cggtccacta
     8701 gtactggatg ttctggagat gctttcacag catgttccat gtaatcttct aaatctcgct
     8761 ggttttcaac gatttccatc gcacgtccgc ctaatacata gcttggacga acaagaactg
     8821 gataaccaat tctcgaagcg ataaccacgg cttcttcttt acttgtagca gtatccccta
     8881 aaggttgagg aatatccaac tctttcagcg cttgctcgaa taaatcacga ttttccgcac
     8941 gatccaagtc ttcgatcgtt gtccctaaga tttttacacc agcagcagtc aaaggttcgg
     9001 ctaagttgat tgctgtctga ccaccaaatt gaacgattac tcctatcggc tgttctagct
     9061 cgatcacatt catcacatct tcgaaggtca atggctcaaa atataattta tccgaaatag
     9121 aaaagtcagt cgaaactgtt tcaggattgc tgttcatgat gattgcttcg tatcctgcct
     9181 gctggattgc tttgacagaa tgcacagtcg catagtcaaa ttcaacccct tgtccgatac
     9241 ggataggacc agatcccagt actagaattg agggcttttc tgatcgtgaa ctttcatttt
     9301 catattcata ggaactataa aaataaggtg tttttgattc gaattccgct gcacaagtgt
     9361 caaccatctt atatacagga atcaaatcat tttcttttct catctggcga acggcttctt
     9421 cgtttatttc ccacagctcc gccacttttt tgtctgtaaa accgttttgt ttcgctgttt
     9481 tcaatatctt gtcatccaac ggctgctgtt tcaactgctg ttcgatttct acgatatgca
     9541 acagtttatc taaaaagaat aaatcgattt ttgtcaaatc cgctaattct tctatggtgt
     9601 accctcttct aatagcttca gctacataaa acaggcgatc atcttgtgct cgaaccactt
     9661 tttggattag gtcatcgtcc gtgatgtctg ccaactcagg aagttcgata tggtgtgtac
     9721 cgatttctaa agaacgcaca gctttcaata aagactcttc gatattccga ccgatagcca
     9781 tcacttcacc agttgctttc atctgcgtgc ctaaaagccg ttctccgttt tcaaacttat
     9841 caaacggcca gcgaggaatt ttagctacaa cataatctaa tgcaggttca aattctgcaa
     9901 aagtcgttcc tgtaacagga tttttcattt cgtctaatgt taatccaagc gctattttag
     9961 cagctagctt agcgatcgga tagccagtcg ccttacttgc taacgcagat gaacgagaaa
    10021 cacgcggatt gacttcaatc acataataat taaaactatg tggatcaaga gcgagttgga
    10081 cattacagcc tccctcgatc ttaagtgctc gaataatcga aagagaagca tcacgaagca
    10141 tttgatattc atggtcagac aatgtttgac taggggcaaa tacgatagaa tcacctgtat
    10201 ggatacccac cgggtcaaaa ttttccatat tgcagacaac gattgcatta tcagccgaat
    10261 ctctcatcac ttcatattca atttctttaa aacctgcaat acttcgttca atcaaacatt
    10321 gggtagcggg ggaaagactt aatccatttt ctgatacgat acgtaattct tcttcatttt
    10381 cacacatacc tccaccagtt ccgcctaaag taaaggctgg acgaacgatg acaggatagc
    10441 cgattttatt tgcaaaatct acagcttctt ctactgtatt gacgatttca gactcgggga
    10501 ttggctgatt caattctttc atcaactgtt tgaatagatc acgatcttct gcttgatcga
    10561 tcgcagaaag ctttgttcct agaagttcta tgttcaattc ttctaaaata cctgatgctg
    10621 ccagctccat tgccatattg aggcctgtct gtccgcctaa agttggaagg agagcatctg
    10681 gacgctcttt tcgaagaatc cttgatacaa attcaagtgt gatcggttcg atatatactt
    10741 gatctgccac ttctttatcc gtcatgatcg tcgcaggatt agaatttact aaaaccactt
    10801 catatccttc ttcttttaag gcaaggcagg cttgtgttcc tgcgtagtca aattctgcgg
    10861 cttgaccaat gatgatcgga ccagatccaa tcaccataat tttcttgata tctgtacgtt
    10921 tcggcatctg tttactgctc ctttcctgcg tccatcattt ccataaattc atcaaataaa
    10981 tgtagtgcat catgcggacc aggggcagca tctggatgaa actgcacact gaaagcggga
    11041 taatctctgt gtttgactcc ttctactgtt ccgtcattta cttctacatg agttacgatg
    11101 agtttttctg gatcaatcgt ggcttcatcg actgcatagc catgattttg agaagtaaaa
    11161 tcaattcttc cggtcgctac ttctcgtacc gggtgattta atcctcgatg tccgaatttc
    11221 attttatagg tatctgcacc gttggctaaa gcaaataact ggtgaccgag acaaatacca
    11281 aaaatcggta cttttccttg gatttttttg atcatttcga ttgcttctgg cacatccttt
    11341 ggatcaccag gtccattcgt cagcatgact ccgtctggtg atagcgctaa aatcgtctcg
    11401 gcatctgtgt tatagggaag tactgtgagg ttacagtttc ttttactcaa ttctcgtaaa
    11461 atactatgtt tcaagccgaa gtcaatgaca atgactttcc gacctgttcc tggacttgga
    11521 taaggtttgt tagttgagac ttgctgcact tgattggttg ctagaacggt tgctttcagc
    11581 tgatcaaatg catgttcgaa ggaatctcca gcatcaacga tactagcttt catcgttccg
    11641 acttcacgga ttttgcgagt aagggcgcgc gtatcgatac ctgatattcc aggaattcct
    11701 ttttgtttca aaaatgaatc tagcgtcatt tggtttcgcc agtttgaagc tacacgtgca
    11761 tgttctttta ctactactcc tttgcatgtt ggagaaatcg attcataatc atctctattt
    11821 accccataat tacccaccat aggataggta aatgtaatga tttgaccgtt aaaactttga
    11881 tcagtgatag tttcttgata accagtcata cttgttgtaa aaacgatttc tccgaagaca
    11941 ctagcatctg caccaaaagc ctttccttcg aaaactgttc catcttctaa tataagcaaa
    12001 cgttccatac ttttattctc ccttctgcca cacaagtttt ccgttgacaa aagtcatttg
    12061 tgtttcgcct tttactttcc agccgataaa aggtgtattc tccccttttg ataaaaagtc
    12121 ttctttatcg atcgtgcaag tttgtgtaat atcaaaaact gctacatcag cgggggcacc
    12181 aaccgttagc gttcctgcat tcaaaccaaa aatctcagcc ggtttaactg ccaaccaatt
    12241 gatcacttgt tccaacgtga atcgaccagt ttctacaaaa tgagtataga tcagttgaaa
    12301 cgctgtttcg cttcctacga taccaaatgg tgatttcatg aaactttggc ttttttcttc
    12361 taatccatgg ggggcatggt ctgtagcgat gcaatcgatc gtaccgtcaa gcaagccttc
    12421 gatcaaagct tctctgtcct cccgtcctct tagcggcggg ttcattttcc aaaagccgaa
    12481 atcttcggga atatcttcgt cgatcaaaat aagatgatgg ggtgaaactt ctgctgttac
    12541 gtggattcct gctttttttg cgtctctgat tacacggaca ctttctttag tagaaacatg
    12601 gcaaacatgg taatgaacac cagttgcttc agctagcaac agatctctag caatttgaga
    12661 agactcggtt acgcttaaga tcccgggaag accaagttct tctgccttct tgccagcgtg
    12721 cataacgccg ccaaataata aagattcatc ttctgtatgg gctactaggg ctttattgtt
    12781 ttttgcagct tctttcatag ccagatacat cgtcccagct gtttggacac ctacaccgtc
    12841 atttgtgaaa gcaaaagcac cttcttcaat cagtgcttct tgatcaacta atttctcact
    12901 tcgcagattt tctgtgattg gcgcatactg caataccttc acaactgcat cttttctaat
    12961 gatgtcatat acttgtctca gcttttctgc cgtatcaggt acaggattta aattcggcat
    13021 cgcgcataca gtagtgaaac cgccacgagc agctgagcga gtcccagctt cgatcgtctc
    13081 cttgtatgta aatcctggct ctctcaaatg aacatggacg tccactaaac caggtgtgat
    13141 caattgtccc tttgcatcaa acacttcatc aaattcggct tctgagaatc ctgtaccgat
    13201 tgctttgatt cgcccatctt ctatccaaat ttctgctggt gtcgtcatat tttttcgtgt
    13261 attgatctga ccgtttttaa tgagtgtttt cattttttca tcctcctata attacgcttt
    13321 tccatttagc actgcttcta agattgccat tctgacgaat actccattgc tcatttgctg
    13381 aacgatccgc gactgtaatc cttccactaa tgaatcagct aattctacat cacggttaac
    13441 tggtgctggg tgcataatga ttgcatgttt ttgcaacttc ttcgcacgct caactgttaa
    13501 cccatgttcc tgatggtagc cttcttttga gaaactttct tttccatcat ggcgttcgtg
    13561 ttgcacccga agcatcatca tgacatcaac ttgatctagt agttcatcca atggcatata
    13621 atgtccgtac acttcgaatt catcgtcgta ccattctcta ggacctgaga agaatacttg
    13681 tgcgcctaga cgttttaaca tctgcatatt ggatttagct acgcgagagt gagtgatatc
    13741 acctacgatg gcaactttca gaccttcaaa atgaccaaat tcttcataaa tggtcatcaa
    13801 atcaagcaag cattgggttg gatgctgtcc gcttccgtct cctccattga taatcgaaca
    13861 ctggattgtt ttactttgta tcagttcgtc ataatagttc tcatcaccat gacggataac
    13921 cgctacgtct acgcctaatg ctgacatcgt cagtactgta tcgtatagtg tttccccttt
    13981 ttggacagag cttgtgcttg cttcaaattc aatcacttct agccctagtt ttttctccgc
    14041 tacatcgaag cttttatgtg tgcgagtact attttcgaaa aagaggtttg tagcaaagta
    14101 ctggcgcttt tgcggagtcc aattagcacc ttgcttgaat tcctgccctc tgcggatcaa
    14161 gcccataact tcttgatcag taagtgcctc aacggtcaat aaatgcttta agctgatacg
    14221 ttctgatttg atgatcataa tgtttcctcc ttagttttct tcgcttcgtg aagtttctgg
    14281 taagataaga tttaaaatga tgccaagtac agttgctaat gccattgccg acaatgtaaa
    14341 tgtgcctact tcaaagacga gtccgccaat tcctactact aagataactg aagcaatcaa
    14401 cagatttttc tttttatcaa aatcgatttt gttctcgatt aaaatcttca ttccacttgc
    14461 ggcaattact ccaaataaga taaaactgat tcctgagatg actggtccag ggatacttaa
    14521 aatcaaagcg cttaattttc ctacgaatcc taaaatgact gcaaatactg cagctccacc
    14581 gatcacaaac acgctatgga cacgtgtgat agccagaaca ccaatgtttt caccgtaact
    14641 tgttacagga ggacctccga caaaggctgc cacgatttgt gctaatccat cacctgtcaa
    14701 cgtcttatga agacccggtt cttcaaagaa attacgttta gttagtttat tcaataccat
    14761 aagatggccg atatgctctg tcatcgtcac aaaagcgatg ggtgccattg ttgtgattgc
    14821 tccaagatat agctttggtt catattgtac aaagggaatc tcaaagttag gaacagcaaa
    14881 ccaggcagcg tctacgattg gcttagtatc cacgattcca aacagcaagg ctacgatgta
    14941 tccgctaata atacctagta aaatcggaat caatccgaga aaacctctta gccacatgtt
    15001 gaagaaaatt gttaatccta atgtgatcag cgctacagca atatacttga aatcatacgt
    15061 gccctgatta tacatagcat ttgttgctgc atttgccgca agtcccaacc cgataaccat
    15121 gatgactgga ccgacgacga ttggaggcaa gattttatcc agccatgctg aaccgatctt
    15181 tttgatgatc agcgcaacaa tcaaatagac taatccagtt gtgactgctc cttgtgcaat
    15241 cgctggataa ccatctgttt tcatcaaaag ctgcatcgct gcaatgaaag cgaagctgct
    15301 tcctaagtac gcaggtatct ttcctttagt agtaaataag tacaccaatg tacctagtcc
    15361 tgaactgact agcgcaatac ctggatcgat acctactaag atggggacta acacggttgc
    15421 tccgaacatc gtgaacaagt gttgtaaact taatcctacc caatgtcctg gggttgggcg
    15481 atcgtggata tctaacacca cgtcatcatt atgaaatcct tttttctccg acatgtttct
    15541 ctctcctcta atcttcctct ttcaaaatca tgatgcgatc ttgtccatca agctcttgca
    15601 tctctactaa aatctcttcc gcccgagatg ttggaatgtt cttcccaaca taatctgcac
    15661 ggattggcaa ttctcgatgc ccacgatcga ccaggactgc taatgaaatt tttcttggtc
    15721 tgccaaaatc cattactgcg tccattgctg ctcgaatcgt tcgtcctgta tacaaaacat
    15781 catcaatcaa aataacttct tttccttcta aggaaactgg gatgtcagaa gaatgaagtt
    15841 ccggttcttc tggattttct tttttgtcat ctcggtataa agtgatatcc agttctccta
    15901 caggaatatc gatatcttct agctgcttca ggcgttcggc aattcttgat gcaatgtaga
    15961 ttcctcgtgt tttgatacct accaatacga tatcttggat actatggttt ctctcgataa
    16021 tctcataagt aattcgagtc aatgctcgct tcatggttac ctgatctact acttcttttg
    16081 cttgcatttt cattccccct acttttttgc ataaaaaaac tcctgcccta agaggacagg
    16141 aggaatgttt agactgagcg tatactgata cactgatagc tatactatgt caatgagcaa
    16201 tctacttatg gcgcaccata cgtatccttg ctcccaccct tcttagcctc acgggactaa
    16261 acttaaagga attctattaa gttttatgct ttcgttgtta attactatac cgttatctaa
    16321 attaaaatgc aatgtttttt cttaattttt ctaaagtttt ttcaaaaact tctggaagag
    16381 gtgcttcaaa gatcatcttt tcgtttgtag tcgggtgcgt aaaacctaac atttgcgcat
    16441 ggagaaactg accattgcct ttcaaagttt tcttcggtcc gtatactgga tctccagcta
    16501 acggataacc gatatacttc atatgcacac ggatctggtg tgttcttccg gtttctagtt
    16561 ttaattcaac cagagtaaat ccttcgaaac gttccaatac agtaaaatgt gtgacagccg
    16621 acttcccatc ttctcttatc gcctgcattt tccggttttc cttcgaacgg ccgattggcg
    16681 cattgatggt tcctttttcg tgaggaatct ctccatggac taaagcaaca tatttgcgca
    16741 aagaggtctt atcttttaat tgctgagcta atgattcgtg tgcctggtca tttttggcaa
    16801 ccattagcag tccggaagta tctttgtcga ttcggtgaac aatacctgga cgaataacgc
    16861 cgttgatcgt agaaagatcc ttgatatggt acatcagcgc attgaccatt gtgccatgcg
    16921 tatgacctgc tgaaggatga acgaccattc cttgaggttt gtttatcacc gctacatctt
    16981 catcttcgta aacgatcgtc aacgggatat tttctgggac cacatctaat gtttctggtt
    17041 cggggatcaa gacagtaatc tcgtctcctt gttttacttt gtaatttgct ttgactggct
    17101 gtccattgac agaaaccgct ccatttttca gccacagctg aatttgcgaa cgactgtaat
    17161 cggtgaataa attagtcaat actttatcga tcctaccaga ttcatggtga atcgtcgttt
    17221 taagttctgt catttttttc tttgatcctt ttcatctaaa ataatataaa ttaacataca
    17281 aatcactcca catacaagtg tcacatctgc tacgttaaaa atcggaaagc tcataaaatc
    17341 tgtctggaac atatctacta catagccaag acgaatacgg tcgataaaat tgccaatcgc
    17401 accagctaga atcaaactca atccaatcat gaaccagcga ttaccttttt cacgattttt
    17461 aatcatcaat gtgagaatca caacgactgc aatgagtgtc actatagtaa agaaccacat
    17521 cttcccttct agcatactcc atgcggctcc agtgtttcga atatgattca gtgacaaaat
    17581 acctggtata agatttttcg tctctccaag cgctagatta tcagtgatcc accatttgac
    17641 caactgatcc actcctacta gcaaagcgct gaatatccaa taaataatta acaaaaaatc
    17701 aatccttttc tatttgttta taaatatcac gaggtcgtac gatcccgagc agattaccat
    17761 cgggattccc atctttagtg ataagtacgg cttccaaagt cccttgctca cgaaacatcg
    17821 cttcaacctc gtaaatatgt gttttagctg gaacaaaatg ataatttgtg tactttccgt
    17881 tttggatgat caaatccaac gctcgtttat ttgttaaatc aaccggacct ttttggcttt
    17941 cttttgctag ccaaaacccg atattacgta aagtaatcaa tgctacaaat tttcctttat
    18001 tgtataacgg aaattgtgaa tacctttttt ctgctactat ctttaacagt tcaagtaacg
    18061 gaagatcttg ttcaaaacct gttacacgtt ttgcaaatcg aggcagcacg gtttcaggct
    18121 gaatcagttc ttgttcgatc agctggattc gcttgactgt ccaatcattt ggctctgcaa
    18181 tgacaaaatc gactgcgatc cgatcatgga cgatcgcatt ccttaactga gcaagctgta
    18241 aaagatcatc ttcgtatttt ctgatcatta attgttttct ttgagctagg cgtctgacaa
    18301 gttcggtaaa tcccatattt cgtgcatttc ccatctcgtc tctcatccat ttttcgattc
    18361 gattgaaact gattaaaaaa agatcagagt ttgccataat tttcctcctt gatcaaatat
    18421 gcccggtttt ttatatagaa aaagaacgca atcaacacaa taactgcaaa aaaactgaaa
    18481 aataaatttt gtaggaaaac ggcccccaac ccagttgcta gaaataaaaa cggatagatt
    18541 tgaagaatca agtaattcat tgtgatcaca taagcaggct ttgcttcttt cactgtataa
    18601 acggggcttt ttagccaata aaaggtgacc tgcatcgtaa agggcacttc cagatcaagc
    18661 gttatctttt gttcatgact gagaacactg cgtttttcat tgttgattct tagctgaatc
    18721 gagctaccca taccgtaaaa accggttttt cttataaatg tcgttttcat cataccctcc
    18781 tattatgctt tagtatagct caaaatacaa taaagaaaaa gaatgatcct agtgtaaaca
    18841 aaattaattc cctatcgtct aaaaaaagaa gctgtagtca aaatacagct ccttcgatgg
    18901 tagattataa tcaagcttaa aacaatccca acacttctcc gtcatttgtc acgtccatat
    18961 tcaatgcagc aggtttttta ggcaaaccag gcatcgtcat aacatctcca gtcaaggcta
    19021 ctaaaaatcc tgcccctaat tttgggatga tttcgcggat cgtgatggtg aaatcttccg
    19081 gtgcacctag cagtgaagga tcatcagaaa atgaatactg tgtttttgcc atacaaatcg
    19141 gcagtttgtc ccatccattc ttcgtaaact cttctatttg tttttgcgct tttttgctga
    19201 aaacaacacc atttcctccg taaattttct tgacgattgt ttctgtcttt tcttgtatcg
    19261 tttcttctag gcggtataat ggcttgtaat tagcttcttt tctatcaatc aatcgtacta
    19321 cagcttttgc taaatcaacg ccgccttctg ctccatctgc ccatacactc gctctcttgg
    19381 caagaatccc ctgattttca cacaagtgct ccaacagtgt gagttcattg tctgtatctg
    19441 ttacgaattc attgattgcg acgatcacag gtagctgata ttgttccata ttacgtatat
    19501 ggcgctttaa atttgcaaaa cctactttca aagcatcaag attctcattt ttaagttcat
    19561 cttttttcat tccgccatgc attttcaatg cacggacagt ggcgacaatc accacagcat
    19621 ccggcgcttt tttcaagtta ggtactttga tatctaaaaa tttctctccg ccaagatctg
    19681 caccaaatcc tgcctctgtg acaacgtaat ctgctaatct caatgctgtc ttggtagcta
    19741 aaatactatt gcagccatga gcgatattgg caaacggtcc cccgtggaca aaagctggtg
    19801 ttccgtaaat tgtttgtaca agattcggct tgattgcatc tttcagcagt aatgccagag
    19861 cgccttctgc tttcaagtct ccagcagtca caggctgacg gtcaaatgta tagccgacaa
    19921 cgatccttgc aagacgagcc tttaaatctt caaggtctgc cgcaagacac aagatagcca
    19981 tgatttcgct ggcaactgtg atatcaaacc catcttctct tggaacacct tggattggcc
    20041 cacccaagcc aacaattact ttacgcagtt cacgatcatt gagatcgact acccgtttcc
    20101 aaatcactcg gcgggcatcg atgttcaatt catttccttg atgaatatga ttatctaaaa
    20161 gagcagataa tgcattatta gctgttgtga tagcatgcat gtcaccagta aaatgcaagt
    20221 tgatatcttc cataggcaat acctgtgcat atcctccgcc tgcagcacca cctttgattc
    20281 ccatcacagg accaagtgag ggttctcgca atgcaataac agatttttta ttgattttat
    20341 tgagcgcgtc tcctaaccct acagtgatcg ttgactttcc ttcgccagct ggtgttggat
    20401 tgatggaagt aactaagatc aaatgcccct cagcgttatc ctttgatcga ttgattccag
    20461 aaaaattgat tttcgcctta tatttcccat acagttccaa atcgtcttcc ttaagatcta
    20521 atttactagc cacttcaaca atcggttcta gctctgtttc ttgtgaaatt tgcagatcat
    20581 tcttcatttg attacccctt ttcacgaact ttattcaaca aaatatcttc tttgttaaga
    20641 tatgccaatt ataccttttt ttattcagaa aaaaaacata aaattacagg tttttaattt
    20701 atttgacgta cttataaata ctctttataa tgaaggctat gatcagactt tagaaaggtc
    20761 gtgagtgctt tgaccacagg aattgtaaaa tggtttgaca acaaaaaagg atacggcttt
    20821 atcagttatg atgacacaga agaaattttt gtacatttta ctgcgattga agaagaggga
    20881 ttcaaaactt tggaagaaaa tcaagtggtc gaatttgaga tcatcgaagg gaatcgagga
    20941 acacaagctg cccatgtcaa gaaaggcaac gttcagacta ccgatactag tatgcatgaa
    21001 tagataaaca aatagagtga gacgctaaac gggatgaacc gtacgtctca ctcttttctt
    21061 ttcctgtaaa aattcgtttt tttaggttct gatttttaaa
//
LOCUS       DAIGQM010000054        20107 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.055, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000054 DAIGQM010000000
VERSION     DAIGQM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.055"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            4..2376
                     /locus_tag="NOA48_001983"
     CDS             4..2376
                     /locus_tag="NOA48_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790236.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAESGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVTKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFSLGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2451..3896
                     /locus_tag="NOA48_001984"
     CDS             2451..3896
                     /locus_tag="NOA48_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI0790237.1"
                     /translation="MSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFVFDRRK
                     QRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVENLHFET
                     EKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNFLVRDD
                     RLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFNLKIGD
                     PKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRKKQAFP
                     QSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVIYEEVA
                     KEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKDICREV
                     AKELKACERSNGTYDFDRFYQGKGDINAQILFSYKAEQYYKGYKKHEHEFVPEVKKDW
                     NDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3907..6111
                     /locus_tag="NOA48_001985"
     CDS             3907..6111
                     /locus_tag="NOA48_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI0790238.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSLLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESYRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYHKAAACTSEACDFRLWTTIAKKKLTATQLKEII
                     QNGRTSQPVKGLKGQKGSFEATIVLKEDFTTSFEFSEKKKTNYKKRTRRTTK"
     gene            6127..6276
                     /locus_tag="NOA48_001986"
     CDS             6127..6276
                     /locus_tag="NOA48_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790239.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6357..6953
                     /locus_tag="NOA48_001987"
     CDS             6357..6953
                     /locus_tag="NOA48_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCI0790240.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYSKAEWYELGKIEIKSRYGNPVIAYDPERTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTIRSYIMALN"
     gene            6966..7865
                     /locus_tag="NOA48_001988"
     CDS             6966..7865
                     /locus_tag="NOA48_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCI0790241.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFENRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYEETMDSISNLMEKVI
                     HVEEKERKIAYQRHQQMNREMER"
     gene            7868..8353
                     /gene="ssb"
                     /locus_tag="NOA48_001989"
     CDS             7868..8353
                     /gene="ssb"
                     /locus_tag="NOA48_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0790242.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGILIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8719..8979
                     /locus_tag="NOA48_001990"
     CDS             8719..8979
                     /locus_tag="NOA48_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790243.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9426..9632
                     /locus_tag="NOA48_001991"
     CDS             9426..9632
                     /locus_tag="NOA48_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI0790244.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9632..9856
                     /locus_tag="NOA48_001992"
     CDS             9632..9856
                     /locus_tag="NOA48_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790245.1"
                     /translation="MKTQHKLLNVKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFE
                     DLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            9871..10308
                     /locus_tag="NOA48_001993"
     CDS             9871..10308
                     /locus_tag="NOA48_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790246.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEAGVKPSTIKPSEYQALE
                     LTYGKFIETKKAKTVSSEWLDYFENVNKYGACYIMKKEDNENE"
     gene            10301..11008
                     /locus_tag="NOA48_001994"
     CDS             10301..11008
                     /locus_tag="NOA48_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790247.1"
                     /translation="MSNVVYQLTVEDVSHFLTNKEHLNEVVRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDCKRMPYQRFERKKGQ"
     gene            11389..11568
                     /locus_tag="NOA48_001995"
     CDS             11389..11568
                     /locus_tag="NOA48_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790248.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQELKQKYGKSESRIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            11661..11845
                     /locus_tag="NOA48_001996"
                     /pseudo
     CDS             11661..11845
                     /locus_tag="NOA48_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            11879..12310
                     /locus_tag="NOA48_001997"
     CDS             11879..12310
                     /locus_tag="NOA48_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI0790249.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNLLRSGRNN"
     gene            13247..14521
                     /locus_tag="NOA48_001998"
     CDS             13247..14521
                     /locus_tag="NOA48_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790250.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLAVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
     gene            14575..16002
                     /locus_tag="NOA48_001999"
     CDS             14575..16002
                     /locus_tag="NOA48_001999"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI0790251.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPEDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDHLYMKPVRELEQLRVG
                     SGVETKVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            16015..16887
                     /locus_tag="NOA48_002000"
     CDS             16015..16887
                     /locus_tag="NOA48_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0790252.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNELLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            16982..17977
                     /locus_tag="NOA48_002001"
     CDS             16982..17977
                     /locus_tag="NOA48_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790253.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKDN"
     gene            complement(18582..18689)
                     /locus_tag="NOA48_002002"
                     /pseudo
     CDS             complement(18582..18689)
                     /locus_tag="NOA48_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18805..>20107
                     /locus_tag="NOA48_002003"
     CDS             18805..>20107
                     /locus_tag="NOA48_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0790254.1"
                     /translation="MIIKNLGNVKSIDIHVKDLLIFTGKNNTGKTYTSYILYGILSEL
                     FGARFFNYFSHTEIEPHLQNSLNILLVSKDSIRKKFNNDAKKFLEENLKKIAVRNFKV
                     SENNFKNLSFTISDSEISELTGDIFNYEIKRYSISGIVITIQNVGEKLKISFEPTDSF
                     QYLSKDIEIEDIYKILAQELSKNVISLPKVFYFPAERTGINVFKNELNESRLKTYDTL
                     LNTVQFTNLTNQKKKAALKYDLLKKNIELLMETTDNSSYPKPISDYINYLNNMKNRYE
                     QKNVNNIASYIRDEIIMGKYEIDEKDNSVSFRQKFGKNRYRKERIPFHVVSSSIKSLY
                     GLDYYLENSSKEGDYLIIDEPELSLHPENQVKLAKVITDIVESKIKLITSTHSDLFVR
                     ELTNIVIENKLNSKNNKKNKLSDKNIGIYNFVGNNDINELEK"
BASE COUNT         7342 a         3125 c         4009 g         5631 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgca
      661 ccaactgatt ctctgaagga gaaagaaaaa gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agagttgatc
      781 gatcaactta aaacgttgga taaccaatac gctgcagaat caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgttacga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgag
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcatgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatt gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacaa ttgaagcctg aagactatcc gaaaatcttc
     1501 ccgaaccgcg tctttgattt tcaattggat aaaacagggc agacagaact tcaagttggg
     1561 attcaagcgg tagccaaaaa tattggaatt caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtacgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaattttc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa atgagtctta
     2461 ttgatcgatg taaacagatc gatatagtgg attttgctcg aaacaatgga atggctgtag
     2521 tcaataaagg acgagactat cgcttagaag accatgattc atttgttttt gatcgaagaa
     2581 aacaacgttt ttattggaac agtcaaaata ttagtggcga cattattgaa ttagctaaac
     2641 tttttttcat agacaaagag atccaagact ctaagcaaca atttaaagca gccacagatt
     2701 ttattctaaa gaatgaagac aaaacagaac gagtagaaaa tcttcatttt gagacagaaa
     2761 agtacaaaga tcaccccgtt gattatcaac cactcacaga aaaaggaagg aattatctga
     2821 aggaagaacg aaaactacca gagtggctga ttgattatgc agaaaaagaa gggttgattg
     2881 ccgaactaaa gccaaaacat gaacggcaaa atttcttagt tcgagacgat cgtttagatc
     2941 atgcggtcgc ctttttatgg aaagatccac agacaaatga gacagtaggg gcgagttatc
     3001 aaggaacgtt cattgattat gaacgttttg gtgagagagg cacatataag catatagata
     3061 aaaattcgac agcgaatcat ggctttaacc taaagatcgg tgaccctaag cagttaaaat
     3121 tttttgagag tagtattgat ttacttagct atgctgcact gaatcgtgat cagttaaacg
     3181 atacgtggtt agtttcgatg gaagggttaa aacaccatgt gatcagtcat tattttggtg
     3241 aggcagtatc tgaattgaga aagaaacaag cctttcctca atccatcgag atttgtgtgg
     3301 ataatgaccg tgcaggacat attttctacg aaaaagaaca attaatgggc gcagttgatc
     3361 catttacgaa tcagaaagta cgttgtgaac gaggaatcgc taatgattgg caagtgccaa
     3421 aagaatacaa agtcatttat gaagaagtcg caaaagaaga aaagatcaca ccagaagcta
     3481 ttatggccat acacaagaca gaaaacaatc tgcaattaac gaaccaattg gtttccgctc
     3541 acaaagtaaa tgcgtctttt ggtcagcagc tttctgttaa cgattcaata gaagctatta
     3601 atttgaaaga tatttgtaga gaagtcgcaa aagaattaaa agcttgtgaa cgctcgaatg
     3661 gtacgtacga ttttgatcgt ttttatcaag gaaaagggga tattaatgct cagattcttt
     3721 tctcttataa agcagaacaa tactacaaag gctataaaaa gcatgaacat gaatttgtac
     3781 ctgaagtgaa aaaggattgg aacgatcaat tgaagcatga gatccagcaa caagaaatta
     3841 gaaagcaaaa acgtgcgatg ttgtttcaac aaggcagaca acaagaaagg gagtgagatc
     3901 gtcacgatga aaactgtcat tttagcagaa aaaccgtcac aagcgaaggc ttatgccgat
     3961 agcttttcta aagccacccg aaaagacggg tattttgaga tccaagatcg attgtttcct
     4021 ggtgaaactg tgattacgta tggttttggt catttagtcg agttagattc gcccgatatg
     4081 tacgatgaaa attggaaaca atggtcatta gaacatttac ctattttccc tacacattat
     4141 cactatcatg ttcctaaaga taagaaaaag caattcaacg tggtgaaaca gcaacttcaa
     4201 tcggccgaca ccattattat tgcgacagat agcgatcgcg aaggggaact gatcgcttgg
     4261 acgatcattc aacaagcagg cgccgatcat ggaaagatat ttaaaagact ttggatcaac
     4321 tccttagaaa aagaagccat ttatcaggga ttccagcagt tacgagatgc agaagagacc
     4381 tacccaaaat ttgaagaagc acaagcacgc cagatcgccg attggttgat cggcatgaac
     4441 ggtagcctac tgtatagttt actcttgcag caaaaaggca taccaggaag tttttcctta
     4501 ggcagagtcc aaaccccaac gctttacatg atttatcaat tacaggaaaa gattagaaac
     4561 ttccaaaaag aaccatattt tgaaggaaaa gcccaagtaa tcgctcaaaa tggcgcattt
     4621 gatgcgaagc ttgatccgaa tgaaacccaa gcgacgcaag aagcatttga agattattta
     4681 aaagaaaagg gggttcaatt gggaaaacag ccaggtacga tccaccaagt tgaaaccgag
     4741 aaaaaaagtg cggcaagtcc acgtcttttt tctctatcca gccttcaatc taaaatgaat
     4801 cagctcatga aagctagtgc caaagatact ttggaagcca tgcaagggtt gtatgaagga
     4861 aaatatctaa gctatccgcg aacggatacc ccttatatta cggaagggga atatgcgtat
     4921 ctgttggatc acttagacga atacaagcat tttttaaaag ccgaagcgat tccgactcct
     4981 attcatacac cgaatagtcg gtatgtgaat aataagaaag tccaggaaca ttacgcgatc
     5041 attcctacaa aaacggttat gacagcagcg gcttttgaac aactaagtcc actgcagcag
     5101 gctatttatg aacaagtgtt aaaaacaacg gtggccatgt ttgcggaaaa gtatacctat
     5161 gaagaaacaa cgatcttgac gcaagttcag cagcttcagc taaagacagt cggaaaagta
     5221 ccagtagatc taggttggaa aaagctgttt ggcaaagaga gctacagaaa agaaaaggaa
     5281 gaagaaccgc tacttcctaa agtgacaaaa ggagaagcgg tgacggtaga tctacaagtc
     5341 cttgaaaaag aaacgaagcc accacaacct tataccgaag gtacgttgat cacagcgatg
     5401 aaaacagctg gaaaaaccgt ggatagcgaa gaagcacaat ccatattgaa agaagtagaa
     5461 ggaatcggta cagaagcaac acgagcaaat attattgaaa ctttgaaaca aaaggaatat
     5521 atcaaggtag aaaaaaataa gcttgtggtg acaaataaag ggattttact ttgccaagcc
     5581 gtggaaaaag agccgctgct aacaagtgcc gaaatgaccg ccaaatggga aagttactta
     5641 ttaaagattg gtgagcagaa aggaacacaa gctactttct tagctaatat ccaaaaattt
     5701 gtctctcact tgttggaagt cgtaccagga caaatccaat ccactgattt tggatcgacg
     5761 ttacaagagg tgaaagcagc cagtgaaaag caagaagccg cgcgtcattt agggatttgt
     5821 ccaaaatgcc aggaacaaga agttttactc tatcataagg cggccgcatg tacgtctgaa
     5881 gcttgtgatt ttagattatg gacaacgatt gccaaaaaga aactcacagc gacacagctg
     5941 aaggaaatca ttcaaaatgg ccgaacaagc cagccagtga aaggattaaa aggtcaaaag
     6001 ggttcgtttg aagcaacgat tgttctaaaa gaagacttca caacgagctt tgaattttct
     6061 gaaaagaaaa aaacgaacta taagaaaaga acacgccgca ctacaaaata atggaggggt
     6121 tatcttatgc gaaatacaac acacaaacaa caagaaatcg aaaatcaaaa agcaaaaatt
     6181 cgttcagaac aagagaaatt acgtgccagt aaaagaagac ttcagcaatt aaagaaccag
     6241 caacggattc aaaaagaaat tgaattagat cgataaaatc ttcctggcta ttgtatacgc
     6301 ataaacttat gttatactat atttataagt ttatacgtat acaaaggagg gagaaaatga
     6361 caaaagcaat ggtttacaag ctgctagaag aatttaacgg aactttggct ttgaaggatg
     6421 ccaaaaaagc gggcatttct cctgtaacga tcaaacgtat ggtagatcgt ggagagctgg
     6481 atcgtgagta tccaggtttt ttcaccttac ctggtcaatt tcctgatgaa ttgtttatgg
     6541 cacaaaagaa atatgagcgc ggcattattt cgcatatcac cgcgttggat ttatatgatt
     6601 taacggatat gatccctaga cagatcgatc taaccgtacc ttacggttat cacgtttctg
     6661 aaaaggggtt gaaagaattc gcagttgagt tacactattc aaaagcggaa tggtatgaat
     6721 taggtaagat cgaaataaag agtcgttatg ggaatcctgt tatagcttat gatccagaaa
     6781 gaaccttgtg tgacatttgg aatccctggt acaacgttga ggatgaaatc aaagtaaaag
     6841 caatcaaaaa ctacatggag tcggacagaa aaaatcttag aaaattgaat gagtatcgac
     6901 gaattttgcc tacagacaaa acgatacgct cttatattat ggctttaaat taaaggagaa
     6961 gacacatgac acctacgcaa ttaaaagcaa aagtgaagaa tatttccaga gaaaaagaag
     7021 ttgatccgca gcttgtttta agacatttta tgatggaaaa attcttggaa aaaatctcag
     7081 agtctcctta tcgtgaaaat tttgtgttaa aaggcggctt cttaattggc tcaaagtatg
     7141 gcattgaaaa tcgaacaaca aaagacattg atacgacttt acgggaaatg aaagtaacca
     7201 aagaaacatt gacaacggtt ctaaacgata ttttttcaac gccgacgaaa gaaggcattc
     7261 aatttgagat tcaaggaatg aaagaaacaa gggaagctga ttattatcca gggtttagct
     7321 tacgtgtact ggcacatttg gaaaacatgc ggccagattt taaggtagac gtgacgacag
     7381 gtgactcgat ctatcctgca acgatcactc acagtcataa attgatgttt gaaaatcgaa
     7441 cgattccttt ggaatcttat cctacagaac aaattattgc cgaaaaatta agtgcaacct
     7501 ttgatttttt aacagataat tcgagaggaa aagattttta tgatctctat actattccta
     7561 aaatggaaaa gatcgatgag aagaccttga aagatagtgt gagaaataca tttacacgtc
     7621 gaggaaaaac tgatccgtta aagatttatt acgaaaagga tatggatgta ctgaaaaata
     7681 gtcatgagct aaaagatacc tggaagaaat atcaaaaaag caatccttat gctgcgtcga
     7741 tcacgtacga agagacaatg gattcgatta gtaatttgat ggaaaaagtg attcacgtcg
     7801 aagaaaaaga gcgaaaaata gcttatcaaa gacaccaaca gatgaacaga gaaatggaga
     7861 gataaaaatg atcaataatg taactttagt aggacggtta accaaagatc cagatttacg
     7921 ttataccgca agtggcacag cagtggctac ttttacccta gccgttaatc gtaatttcac
     7981 gaatcaaaac ggcaatcgag aagctgattt tatcaattgc gtgatttggc gcaaaccagc
     8041 agaaacgatg gcgacattag ctaaaaaagg catcttgatc ggcgttgtcg gacggattca
     8101 aacacggact tatgacaacc agcaaggaca acgtgtgtat gtgacagaag ttgtagctga
     8161 taacttccaa ctattagaaa gcaaagcagc gacagagagc cgtgcgcacg ctgatcaatc
     8221 gtccacgagt ccaagcacca ccacttttga acaacgggat acagcgacgc ctaacaacaa
     8281 tggattgaac gcttcacaga atccatttgg tggacaatca atcgatatta gcgatgatga
     8341 tctaccgttt taagtagcat tttctattgg ttgcatttgc tacggtttat gttataattt
     8401 agtcaacaaa aagaattttc aatctataac caaaaaccac tagctggcgg gctagtggtt
     8461 ttcttttacg tttctattat aagaattaac gagtaggctt actgtctttc ttggcaaatt
     8521 tacaatcaag ccatttgcag atatagtgcg cggctacttc tgccatgatt gcaaaaacaa
     8581 aatcaaaaag aattttcaaa cctataacct cctccccttg ccagattagg ccggggtagc
     8641 agacagcaag actattatag cataattgaa atatccaaat gattggattt ttgctataat
     8701 tttagcgagg tgattgtgat gaacaaatat gttggtttgc ttgataaaat ccgagtaata
     8761 aaaacgcaac cgttattggt tcgctttact ttacaaacga ttcatgaatc gattaattgt
     8821 gtagttgcag atattgaaat tatcgataaa ttgctaatta tggatgatgg aaaatacaat
     8881 attgccgtca caggtcactt caataaacga aatcagctgg ttattgctag catgtatgtt
     8941 agaaatcccg atcattttac acgatcgatg ggcatataaa taaaagaaga gttgtagtcc
     9001 taaatgagga ttgcagctct ttttgtttta catagaaacg ggaacaggaa aaggcctgtt
     9061 taggaaggca caagcgcctt ctcaattaaa aaacctttct ctcactccaa ccgccaccgc
     9121 cgttcgagaa gaaaggaagt gaacgctgca cgttcactaa gatatggtgt cttgcaaagc
     9181 aagacaaaat aggaaaagct tcctctcacc aaaaggttcg ttcctgttcg ctatctcttt
     9241 attgatttgc cagaccggca acaagttgcc ttttatcacc aaaaagcgac aaggacaagg
     9301 gtaaatggca cgctgcgcgc ccttgtcctt gtcgcttttc gttgattcat tctggccaac
     9361 aaatcaataa agaaagaact aacgaaagga agtaaaacct ttcctaagag gaggcagaat
     9421 caatcatgcg aaagaaattt gattattggg gtgttccctt cagcgaatta ttcccaaact
     9481 atcatgcacc acatactgtc gaatgcgatt gtggagaaag agcgaaatgt atcaaaagct
     9541 atcgtttgta tcaatgtcca acatgcggga aaaaatatac cttgtcttat ggcgattaca
     9601 ttttgattga tgagaaagga aagaaacgct gatgaaaaca caacacaaat tattgaatgt
     9661 aaaagaagtc atttctgaaa aagtagcaga agctttactt attccgcggt actggacgat
     9721 agaaacccct ttagtagagg acgcaccgac tatgctattt gaagacctag tgaagattgc
     9781 aggatatgaa ctgcattatc aagaaaactt ggaaacttat gaaaacgaat attggttaac
     9841 caaattagag aactaaaaag gagaaaaaat atggctcaga attactatga cgaatttgtc
     9901 aaattacctt tggataaaat ggcacaaaaa atggaggata tgacgttcct ataccatgaa
     9961 acacgtgtac ccaaaaaaca ttacaaggaa aaattgtcag tcgcagtgga agaaatgatt
    10021 gaatcaggtg tcgaaatgaa tctcattgcg acgtactatc gaacattgga agaactgaaa
    10081 aaacaaaatg gaaaatggtt tttccaagcc ttactatgct tggaagcagg cgtcaaacca
    10141 agcacaatca aaccttctga ataccaagct ttagaactaa cgtatggaaa atttatcgaa
    10201 acgaaaaaag ccaagactgt ttcaagtgaa tggttggact actttgaaaa tgtcaacaag
    10261 tatggcgcat gttacatcat gaaaaaggag gacaacgaaa atgagtaatg tggtttatca
    10321 actaacagtg gaagatgttt ctcacttttt aacaaacaaa gaacatttga atgaagtagt
    10381 cagacggatt caaaaagact ttagttgtat ggaagaaatg aagtacttta ttcaaagagt
    10441 ggaagaacag ttgtatatgg aaagcgaaac gagtcaaacg aaggtcacag tcagccataa
    10501 tcatttagac gtgtataaac gtcgtcctga aacggtaaaa aaaggaacag agcttctacg
    10561 actagaaaca gaaaaataca tcatgaatgt gtacctagaa aggagtgagc tggtcgaaaa
    10621 ctttgtcagc tacacgattt gtaggaaaca ctattactca gaatcagaat attattcaat
    10681 ttttgagagc atggaattaa tggaagaaga aatggaagag ctaaacagca aaaatgcgac
    10741 ggtagacgat tattaccttg tatttactag atttctgacg tgtgggacgg aatctatcgt
    10801 gttaatggga atggattatg aactcgctgt acccgaagca tttttgaggg aatatgtaga
    10861 agaagtagat aacccaggcg acgactggta cacgacttta actgattttt tagataccta
    10921 cacttacgac gatacagaag aaatccaaaa tgagcttgac tgtaaacgaa tgccatatca
    10981 acgatttgaa aggaaaaaag gtcaataacc atttataccg aaaagtgaga atgtgtgaaa
    11041 taagaacaaa aaaccttgaa attaagggaa tggttcttat ttcgcaccaa tcgctccaac
    11101 cgcccccgcc gctcaggtgg tgcgaaataa gcgggcaacg accgataacc taagagaaag
    11161 aaggaaatcc atatgaataa aatcattcct ctgttgttcg tactgtttgt tggcgagata
    11221 cttatgcgtc atgctgcagc tgtacattta aacttcgtag tattcttagg aatactggta
    11281 ttttgtttga tcttttggcg atttgtatta gcccttgtga gtctactatt caagatgatt
    11341 gcagccatat ttttcatagg gttatttcga tgaaaggaga gagtactaat gccaattgca
    11401 ataggaaata aacgtttacc cgtgacgttg gatgaaaaga gacaaaaaga attgcaggaa
    11461 ctcaaacaga agtacggcaa aagtgaatcc aggattatgt gtattgcgtt agatttattg
    11521 attgcacaag aaaaagcagg gtttgatgta ccagcactca aaaagtgacg tcacttttca
    11581 tttgaagaaa caaaagtgat agcactttac gcacgtgtcg atacgtgtta tgattatttt
    11641 gtaaggaggt atagtgcaca atgccactta cgggaaaaga aatgcttaag ttattgaaaa
    11701 aaatggctgg gttgagcgaa ggcaagaggg atctcatcat catctttata aggatggtgt
    11761 tagaatcact gttcctgttc atgccaatca agatcttggc cgaggacttg agcaaaaaat
    11821 tttaaaggat gcgggattga aataatctcg cattcgatta aagaaaggat tgactgaaat
    11881 gttaagtgag cctttagcaa aaacctatcc tgctattttt agcccagaag aaggtggtgg
    11941 gtactttatt gaatttcctg atgttcaagg tgcttacaca ggaattaacg aagacgatat
    12001 atcttatgga attgctatgg cacaagaggt gttaggtatg gttttagcag attatattga
    12061 gcatgaagat ctacttccag aaccaacacc aatcaataag atttctgttg aagatgattc
    12121 ttttactact ttaattcgtg tagatgttgc caaatatttg aaagacacag aacttgtcaa
    12181 aaaaacctta acaattcctc aatgggcgga taagctaggc aaaagggctg gcataaattt
    12241 ttcagtcctt ctaacagaat caattgcaga taaagcagat aaccttcttc gttctggaag
    12301 aaataattag aactcaaaag agtcagaaac ttaaaaatct ttggcttctt tttttactac
    12361 aaagatggct tctttaaatt atttgcctga ttgatttaaa aaaattgcgc aaagactacg
    12421 agctaattaa gttgctcgtg gtctttcttt atgaaaactt tttagatcta gataaaaaca
    12481 ttgagacact ttgaaaaatt tttttaatag taatgggcgc ttctatgtca agctgattct
    12541 tctttcggta aattaatttt acttagaata tcactatctt gataaaaaat ggtgtattca
    12601 caaattctgg cataaaaaat acctactttc tagttaaggt tcctgaataa gtcgcaatcc
    12661 aattatttcc agctgattta taacttttta aatataattt tccataatac caataaccat
    12721 tacttttttc tgtccaattt cgttattgag aagatctaga aggccagcca actttatcaa
    12781 aaatcatcat tcctgtcact cgtatcgttt tagaagctgc tcgagtaagt aatggagaaa
    12841 ctgttaaata attttaagta acagttaagt cgttagttgg gttatcaatg gctattccgt
    12901 ccttatctga acctcgaaac ccaatcatag aaaaagtttt ttgaacaagt tttaacagat
    12961 aaatcaagtt atatactaga aaattcgtaa aatatatttt taatgtcata atcgtttgat
    13021 ttttctggat tgacatttat ttataaaaaa tagtgccatt aaaaaagaaa agtgacacac
    13081 caataaaagt catatcctgt gacattatat ggcattatcc aaatagaata accggttgac
    13141 atgtaagcgg attcctttta taattttagg agtataagtc cttttctaaa aatattaacc
    13201 ggttatcatg aaaggggata caaatatatc gttggaggat aaaaatatgt caaaggttaa
    13261 cgtatttaaa aatcaatcct atttacaaag ttcagctaca ttattactat tttttgcttc
    13321 ttggggtgtt tggtggtcat tttttcaact ttggctaaca tctgaatcaa atggtttagg
    13381 gttatctggc agtgctgtag gaacagtatt ctcggcaaat tcgttagtta ccttaatttt
    13441 gatgtttatt tatggaacat tacaagataa attgtatatt aaacgaaatt tattaatttt
    13501 tgcttctgta ttagcgacac ttgttggacc attttttata tggatatacg ggccattgct
    13561 agataacaat tttaatttag gcattattat gggagcacta tttttgtcag ctggatattt
    13621 agcttctgta ggagtttttg aagctgtgtc agaaaggttt agtcgtttat ttggctttga
    13681 atatggacaa gcaagggcgt ggggatcatt tggttatgcc ttggtagcgc ttttggcagg
    13741 atttttattt gtaaaaaatc ctcatttaaa cttttgggcg ggatctttct ttggttcttt
    13801 actattgtta aatttattat tttggaaccc taaagttgaa cgggaagcaa atcaaaattt
    13861 taatcaagaa caagctgaat caaatagtat tccttcttta aaagaaatgt ttgatctaat
    13921 gaaactgcct caattatgga cgataatcat ctttattgtt tttacatgga cattttatac
    13981 ggtattcgat caacaaatgt ttccgggatt ttatactggt ttgttttcaa catcagctaa
    14041 tggtgaaaaa atatatggga cattgaatgc tattcaagta ttttgtgaag cgttaatgat
    14101 gggaattgtt ccaatcatta tgagaaaatt aggggttcga aatactttgt tattagctgt
    14161 aaccattatg tgtgtacgaa ttggattgtg cgggtttgcc tcgacaccat tatctgtttc
    14221 atgcataaaa atgttgcatg ctttagaagt accattattt acattaccaa tgtttcgcta
    14281 ttttacactt cattttgata caaagctatc agcaaccctc tatatgatag gatttcagat
    14341 agctgctcaa attgggcaag tgattttatc aacaccattg ggaatattaa gagacaacgt
    14401 tggctatcaa ccaacattta aaattatttc tcttattgta ttactagcag gcatatatgc
    14461 attctttatt cttaaacaag atgatagaga tgttcaaggg gatccattta ttcgaggata
    14521 atggaaacca acagaataaa aaacaatttt atctagaaag tgagcgaata tattatgaca
    14581 aaaagagcta tagaattaac aaatacacgt tatcgtttgg gatatcatgt gtctgcacca
    14641 tcaggatgga ttaatgatcc aaatggattt tgctattttg atgggtatta tcatgtgttt
    14701 tatcaacatc atccatatag tgctgaatgg ggaccaatgc actgggcaca tgctagaagt
    14761 aaggatttag ttcattggga atctttacca cttgctttga ctcctgaaga tcaagaagat
    14821 gaaggtggtt gtttttcagg aagcgctatt gaaaaaaatg gtgtgttgta tctgttctat
    14881 acaggacatc actattatgg agacaatgat ccagatcatt tttggcaaaa tcaaaacatg
    14941 gcgtatagta cggatggcat tcactttact aaatatgaaa aaaatcctgt aatagcaaaa
    15001 gcaccagaag ataacacaca tcatttcaga gatccaaaag tatggaaaca cgatgaaaaa
    15061 tattacatgg ttttgggtag tcaagaaaaa gatggattag gtcgtgctat tgtttatcag
    15121 tcgttagatt tattaaattg ggattacatt ggaccaattt ctaaagcgaa ggaagtactt
    15181 acagaaggat ttatgtggga atgcccagac ttttttgaat taaatggaaa atctattctt
    15241 ttattatccc ctcagggaat tgaagcaaat ggaaaagatt atttaaatct atatgaaaca
    15301 ggctacttta tcggtgatta tgattatgag acagcaaaat tcattagagg aaatttttat
    15361 gaattagata agggacacga tttctatgca acacaaacaa ctttatctcc agatggtaga
    15421 cgtattgtta tggcttggat ggatatgtgg gaaagcccta tgcctgaaaa agtagacgga
    15481 tgggcaggag cattaacgct tcctcgagaa ttagagttaa ttggagatca tttgtatatg
    15541 aaacctgtga gagaattaga acaacttcga gttggcagcg gcgttgaaac aaaagttaat
    15601 ttggcaggag aaataataat cgctcaagat gcttcattca aagaagctct aattgatgta
    15661 ctattgacta aatcaaaaaa tcaagaaatc aaattttcat taaaaacaaa agatgaagag
    15721 ttaattaata ttttttattc taaggataaa aatgaatgta ccttaactcg taacggcaaa
    15781 aatgatccaa ggtatggaac cattcagatg tgtgatagat tatcacttcg agtgtttatc
    15841 gataaaagtt cggcagagat ttttattaat gatggcgagc ttgtttttac agagcgttat
    15901 tatacagaaa atcaaccaag tatgcatttg agtgttagtg aagaagcttt tgtctcgagt
    15961 acaatttatc atctaaaaaa agatgcaatt tcttacgagt aaggaggttt tatgatgtta
    16021 attggtagca tagaagcagg tgggactaaa tttgtatgtg ccgtgggaga cgaggattac
    16081 cgagtacaag accaaataat ttgtccaacg accaccccca gggaaacatt gaaaaaaact
    16141 gttgactatt ttaaacagtt tgatataaat gcattaggta ttgcatcatt tggtccaata
    16201 gaaattcgaa aaaattcacc aaaatcagga tatattacgt ctacaccaaa ggtgggatgg
    16261 cgaaatgtta atgtgttagg ttatttacaa gatgagctga atgttccaat gtcttggaca
    16321 acggatgtga acggatcagc ttatggagag tacatcatgt ccactttatc gaatgaaaaa
    16381 ataaattcat tagtttatta caccgttggt actggcgttg gtggtggagc tgttgttgac
    16441 ggaaaactat taggatcgtt tggtcattca gaaatgggcc atacgtttgt aaaacgccat
    16501 cctgatgata ttgattttaa aggaatttgt ccttatcatg gtgattgttt agaaggctta
    16561 gttgcgggac caacgtttga agcacgtttt ggaaaaaagg gtgaagacgt ttctttaacg
    16621 gatcctattt gggatgtaat ggcctattat ctagcacaag ctgtgattca aacaacattg
    16681 attatacgac cggataaaat agtatttggt ggaagcgtag taaatgaaaa attgttagaa
    16741 aaaattcgtg ttaatgttaa tgaattattg gatgattacg tggaaatacc accgttaagt
    16801 aaatatatta cgcgtccttt aattaaaaat aatggatcgg caacactagg aaactttgct
    16861 ttgggcttga atcaattaca agaataaaac atagaaaaaa tatcgattat caggtatagt
    16921 agttctatag agttcttttt ttcgatagtt aattattgca ttatttagga gagacaagag
    16981 aatgcgccca aaattagaag atgttgccaa aagagcaaat gtatcaaaaa caactgtttc
    17041 acgtgtatta aacaatcgtg gctatttaag tcaaaaaacg attgataatg tttataaggc
    17101 tatagaagaa ctcaattatc aaccgaacgt tgtagcgcgt caattatttc aaaagaaaac
    17161 taacattgtc gggttactat ttcctacagt agccaatcct ttttttagtg aactcgttga
    17221 ggcattggaa aaaaagttat atgaaattgg ttataaggta ttaataggca attcgatgaa
    17281 taataaagaa aaggaaacaa attatttaaa tcagttattg tctgatcaag tagatggttt
    17341 aattgttggt acacataacc aagggattca ggaatataaa tatcagaatt taccgattgt
    17401 tgcaattgat cgagtgatga atgaagatat tccagttgtt gaatccgata actacaatgg
    17461 tggaaaactt gcaaccaagt tattaattgc acaaggtgca aaaaatatta ttcatacaaa
    17521 cggtccaatt gacttacaga ctccggctaa tcgtcggaga ctagcctatg aagatactat
    17581 gaaagcatat cagttaattc cacgaactgt gacattagat ttcaatattt cttatgtaaa
    17641 gaaaaaacag atttttttcc aaatgtttga ggattatcct aaaatagatg gtatttttgc
    17701 ttcaaatgac atcgatgcgg ccctaatatt acaagtagca aaagaaaagg ggttaaatgt
    17761 accagctgat ttattagtag tcggatatga tggtacttta atgactcgga gtatattacc
    17821 agatctgaca acagtaatac aaccaattaa tgatatagca gacacagctg ttgctatttt
    17881 gatgaaacga ataaataaag aagaaacaaa aaaggaatat attttacctg tcacattatg
    17941 gatggggaag acatcagtaa agaaaaagga caattaaatt tataaagact atcaatgata
    18001 atttcattat taattcgtga tataaaaagt tgttaaatct cttataatag actatgatac
    18061 aaaatcatgc ttttaatctg tgtagatgtt gccaaatatt tgaaagacat agaacttgtc
    18121 agaaaaacct taacaattcc tcaatgggcg gataagctag gcaaaagggc tggcataaac
    18181 ttttcagtcc ttctaacaga atcaattgca gataaagcag ataacattct tctttctgga
    18241 agaaataatt agaactcaaa agggtcagaa acttaaaagt ttttgatcct ttattttcaa
    18301 gtctgatttg acagattttc ggcagctcat ttatttatgg tcagaaatag ttgctgaaat
    18361 tttaatctat tagcaaatag tccagaacgt atgaagagga ttcggatatc atttgtcatt
    18421 aacaccataa atatttataa aattcgtgtt cacctacaat taaatttaat atataatatt
    18481 cgttgtaagg gcttataatt ttttgttaat gaacaagata tgtaattgat agtgtcaata
    18541 gctattcaaa aatgtaggct tttggcccat aaataacaag gttacttata tgataacttt
    18601 ttttctttat aatctttaat ccgatagagc tttccagtag tttgaataat cttagcgtgg
    18661 tgcactaatc gattgattag tgcatttgtg ttcagtccat tgagacataa tagtggatag
    18721 ttttactgag aaaattgata aaaaatagag atataattca aatacgtata taatgaaact
    18781 aaagataaat acggaggaaa atatatgatt ataaaaaact taggaaatgt taaatcaata
    18841 gatatacacg ttaaagattt gctgattttt actgggaaaa ataatacggg aaaaacatat
    18901 accagctata ttttatatgg aattttatca gaactctttg gagcaagatt tttcaattat
    18961 ttttctcata cagaaattga accacattta caaaatagtt taaatatttt attagttagc
    19021 aaagactcta taaggaaaaa atttaataat gatgcaaaaa aatttttaga agaaaattta
    19081 aaaaaaattg cagttcgtaa ctttaaagta agtgaaaata acttcaaaaa tctttctttt
    19141 actatttcag attcagaaat tagtgagctc actggtgata tctttaatta tgagatcaaa
    19201 agatacagta taagtggcat tgttataaca attcaaaatg taggagagaa attaaaaatt
    19261 agctttgagc caactgattc atttcagtat cttagcaaag atattgaaat tgaagatatt
    19321 tataaaattt tagctcaaga gctatctaaa aatgttatta gtttgccaaa ggttttttat
    19381 tttccagccg aaagaactgg tataaatgtc tttaagaacg aactaaatga aagtcgctta
    19441 aaaacatatg ataccttgct gaatactgtg caatttacta atttaactaa ccaaaaaaag
    19501 aaagctgccc tcaagtacga tctgttaaaa aagaatattg agctgttaat ggagacaacg
    19561 gataatagtt cttatccaaa gccaatatcg gattatatta attatctgaa taacatgaaa
    19621 aatagatatg aacagaaaaa tgtcaataat atagcatcat atattagaga tgagattatt
    19681 atgggtaaat atgaaattga cgaaaaagat aattctgtaa gttttagaca aaagtttggt
    19741 aaaaatagat atagaaaaga acgaattcct tttcacgttg tgtcttcttc gattaaatct
    19801 ctatatggat tagattatta cttagaaaat tcaagtaaag aaggagacta tcttattatt
    19861 gatgagccag aattgagttt acatccagaa aatcaggtta agttagcaaa agtaattaca
    19921 gatatagttg agagtaaaat taagctaatt acttctaccc atagtgattt atttgtacgt
    19981 gagcttacaa atattgttat tgaaaataaa ttaaatagta agaataataa aaaaaataaa
    20041 ttgtctgata aaaatatagg catatataat tttgtaggaa ataatgatat aaatgaatta
    20101 gaaaaaa
//
LOCUS       DAIGQM010000055        19888 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.056, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000055 DAIGQM010000000
VERSION     DAIGQM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.056"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(165..986)
                     /locus_tag="NOA48_002004"
     CDS             complement(165..986)
                     /locus_tag="NOA48_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0790255.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(1083..1361)
                     /locus_tag="NOA48_002005"
     CDS             complement(1083..1361)
                     /locus_tag="NOA48_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790256.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            1629..3638
                     /gene="metG"
                     /locus_tag="NOA48_002006"
     CDS             1629..3638
                     /gene="metG"
                     /locus_tag="NOA48_002006"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCI0790257.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(4117..4704)
                     /locus_tag="NOA48_002007"
     CDS             complement(4117..4704)
                     /locus_tag="NOA48_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790258.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            4879..6201
                     /locus_tag="NOA48_002008"
     CDS             4879..6201
                     /locus_tag="NOA48_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0790259.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            6356..7132
                     /locus_tag="NOA48_002009"
     CDS             6356..7132
                     /locus_tag="NOA48_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0790260.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            7125..7694
                     /gene="rnmV"
                     /locus_tag="NOA48_002010"
     CDS             7125..7694
                     /gene="rnmV"
                     /locus_tag="NOA48_002010"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCI0790261.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            7687..8571
                     /gene="rsmA"
                     /locus_tag="NOA48_002011"
     CDS             7687..8571
                     /gene="rsmA"
                     /locus_tag="NOA48_002011"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCI0790262.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            9022..9651
                     /locus_tag="NOA48_002012"
     CDS             9022..9651
                     /locus_tag="NOA48_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790263.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(9775..10884)
                     /gene="ugpC"
                     /locus_tag="NOA48_002013"
     CDS             complement(9775..10884)
                     /gene="ugpC"
                     /locus_tag="NOA48_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCI0790264.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            11093..11515
                     /gene="mgsA"
                     /locus_tag="NOA48_002014"
     CDS             11093..11515
                     /gene="mgsA"
                     /locus_tag="NOA48_002014"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCI0790265.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            11838..12374
                     /locus_tag="NOA48_002015"
     CDS             11838..12374
                     /locus_tag="NOA48_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0790266.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(12414..14177)
                     /locus_tag="NOA48_002016"
     CDS             complement(12414..14177)
                     /locus_tag="NOA48_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790267.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(14180..15895)
                     /locus_tag="NOA48_002017"
     CDS             complement(14180..15895)
                     /locus_tag="NOA48_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790268.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(16674..16898)
                     /locus_tag="NOA48_002018"
     CDS             complement(16674..16898)
                     /locus_tag="NOA48_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790269.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            17089..19866
                     /locus_tag="NOA48_002019"
     CDS             17089..19866
                     /locus_tag="NOA48_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0790270.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEVKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
BASE COUNT         6433 a         3590 c         3952 g         5913 t
ORIGIN      
        1 aacaatagca gaaaaagttc gtacgagctt tttctgctat tgttaatttt ttattcagaa
       61 agtttacgaa tacatcaaaa ttctgaaaca aaaaacgtaa ctcacaaaga gttgtttttg
      121 cgttttttct tgaatgatta ggtctgaatc ttttgctcac aaccttattc atggtgcccc
      181 ggcttgagct gatagatttt tgaaggacgg ccgattccta caggacgttc accgatctca
      241 tcgaaatatt ggagcatagc tttcttaaaa ttggaatgat cgatcgtttt ataatcgatc
      301 cctaagaatt tagcaaatac ttttcgagct tccgtaatcg tgaaatcttt acctaaaact
      361 tgtagaactt gcggctcgtg ttccatttta ttgactacac ggttgaatgc tttcaagatg
      421 atttgactat ggtcaaaagc caaagtatct ttgccagaag actctccagt gactaaatca
      481 agcgagatag ccacttctcc gctagataaa tggatcttgt tactatgacg ttctagtgtg
      541 aaccagcgta cttccttggc atcatctccg gcgattagcg gttcttctcc aataaaggct
      601 aagtagctga ctgtgacgac ccagcctcgc ggatctcgat taggcgtact gaatgtatgc
      661 agttgctcaa tattttcttt tgaaataacc acaccagttt cttcctttgt ttctcttaag
      721 acgctttctc cagttgactc atccttttgg acaaagccac caggcaatgc ccatgaattt
      781 cgataaggat gcccttttct ttggatcaac aaaactttca gctgatcttc ttctttgtta
      841 tagcacatca gtacgatatc gacagtcaaa gagggcttgt catattctgg acgttcctgt
      901 ttttgatacc agttaagaaa ttcttcttca cttgctttat gttcataata taatttttct
      961 tcttctttag aagcaaaacg gttcatctga ccacctccat tgacagtaaa agtacttttt
     1021 accttattgt agcagactct gaaaaaaaac caaggattta cttgaaaaat ctaggttatc
     1081 atttaaatat gaaaaataaa tggaagtatg agattgaata aaaagaaaag cagataaaac
     1141 ggcaatactt tataccgctc ttcacgaatg gcaaagaagc cacaaataac gatatatacg
     1201 tcaatgataa aacgcaaaat ccaagctgct gtcataaaac tgttcaaatg cccatggagg
     1261 ttaaaataac catacatacg aatataaaaa tagctgaata ttaaatgtgc taatgaaaga
     1321 aaagcaatac taagtgtaaa aaaaagatgt ttcttctgca tgattgttcc agtcccttac
     1381 taagatagat agtctttatt ataccacgtg tgaggggaga aataaaaagc cgttttttag
     1441 tagatatgaa acaaaacaaa aacccgcatt tattcaacct attcatcctt ttaaaggata
     1501 gattgaacgt agatagaagt cgtttatcca gtctttttca ttttgaaaaa aagctaacag
     1561 catgcttttt ttatggtata ctagcaagga aacgaattcg catcatgcga taaaggagga
     1621 agagccccgt ggcagaaaag gaaacttttt atatcactac gccaatctat tatccaagcg
     1681 gcaaacttca tatcggcaac tcgtatacta cgattgcatg tgacgcaatt gctcgttata
     1741 aacggttgat gggctttgat gtgttttatc tcactggagt ggatgaacat ggtcaaaaaa
     1801 tcgaaacaaa agcagaagaa ctaggtgtaa aaccgcaaga atatgtagat aaaatggcgg
     1861 ctgatgtcaa gaaattatgg aaaacgcttg atatcagtta tgataaattc attcgcacga
     1921 cagatgatta ccataaagca gctgttcaaa aaatatttga tcgtttatta gaacagggag
     1981 atatttactt aggtgaatat gaaggctggt actctgtttc tgacgaagaa ttctttacag
     2041 aaacacaact tgcagaagtg tacaaagatg acgaaggtaa cgtgatcggt ggtaaagcgc
     2101 caagtggaca cgaagtagaa ttggtaaaag aagaatcata cttcttccgc atgagcaaat
     2161 acgcagaccg tctattggaa tactatgaag aacatcccga attcatccag ccagaatctc
     2221 gtaaaaacga aatgatcaac aactttatca aaccaggatt agaggatctt gcagtttcac
     2281 gaacaacttt tacttgggga gtaccagtca agagtgatcc gaaacatgtg gtgtatgtat
     2341 ggatcgatgc attatccaat tatattactg cactaggata tggctccgaa gatgaaagtc
     2401 tattcgaaaa atactggcct gcagatgttc agatggtcgg taaagaaatc gttcgctttc
     2461 atacgatcta ttggccaatc atgctgatgg cccttgattt gcctctacct aaaaaagtat
     2521 ttgggcatgg ctggctattg atgaaagacg gaaaaatgtc taaatcaaaa ggaaatgtcg
     2581 tttatcctga aatgcttgtg gaacgttatg gtttagatgc actccgttat tatttgcttc
     2641 gtgctgttcc gtttgggtca gatggtgtct ttacgccaga agattttgtt tcccgtgtca
     2701 attatgatct ggcaaatgat ctagggaact tattgaatcg aacgattgct atgatcaaca
     2761 aatattgtga tggactcgtt cctgactatg cctcacttgt cactccattt gatagtgaac
     2821 tgtctacgac ggctgctaac gttgtcggac gttaccatga tgcaatggaa aaaatggaat
     2881 tcaatacagc attggctgaa atctgggtgc tgatttctcg tgcaaacaaa tacattgatg
     2941 aaacagaacc atgggtatta gcaaaagacg aagaaaagaa agctgaattg aatagtgtca
     3001 tgatccattt agctgaatct ttgcgtatcg cagcgatatt acttcagcca atcatgacag
     3061 aaacgccaga gaagatcttc aatcaactag gattggactc tgaaacaatg aatcttgaag
     3121 gattacactt tggcgaattt ccttcaggaa caaaagtagt tgcaaaaggt acaccaatct
     3181 tcccacgttt agatatggaa gaagaagttg cttttattca agaaaaaatg tctgaaggta
     3241 ctcaaacaaa cgaagataca gtcaaatggg atccagaaga aacagaactt gtttcaacga
     3301 aagaaaaaca aatcaaattt gatgtatttg aaaaagtaga actaaaagta gcagaagtca
     3361 tcaactgtca aaaagtagaa ggggcagata agttgctgca attccgacta gatgctggag
     3421 acagccaaga ccgtcaaatc ttgtcaggaa tcgctgaatt ttatcctgat ccaagcgaat
     3481 tgatcgggaa aaaagtcgtc attgtagcaa atctgaaacc acgaaagatg cgtggacaaa
     3541 tcagtcaagg aatgatcctt tctgcagaag caccagatgg ctctttacaa gtaatcgaag
     3601 caccaaaatc catgccaaat ggctcagaaa tcgcatagaa attcaaaggg ggtatgacac
     3661 tagttgtgtc ataccccctt tttccgaaat ttgagaagca attttcgtaa attccttctt
     3721 attacttgaa gccaatcata taatacagaa acagagaact atccaaaata aatcctagaa
     3781 aaagaagtac gagcttcgct gatttttgtt aatttagaat aatactaata ggaatcgtaa
     3841 aaacagaaaa aaagcataat gataaagggt cgggcagatt ttaattgatt catctggtac
     3901 tcttttttat tgtccttaca ttcataaagt ttgaatgcaa tgactttatt acatctatat
     3961 ttatatctaa cagtagcgtt gatgtgttaa ttataagttc tatcacttta tgttcaatta
     4021 gtttgtgctc ttatatgtgt gattgaaaat atagataaaa aaacaatcat cggctttgac
     4081 ttcgatgatt gttttcttta ttttgtaaaa atcctatcac ttgattttat ggtaaccttt
     4141 tatttttgtc ttcaaacggc ttggtaagag agcagtaagc agtgcaaatg ggatcgaaaa
     4201 gacataccag aaaatcgtac gtccgatacc ataatgttga tagagctttg tcaacatcac
     4261 gtgtaacaag atcaacccta aaagcaagga gccagctata aaccaatgat tatcccaatg
     4321 catgacttca ctaagtgcca tcactccaaa aggatagaaa taaaaataga tcccgactaa
     4381 ggtcatccgc cagttctttg taaatgttcc gatattcaat aaaaagaaaa tcgctgaaag
     4441 caaaataccg ataggcggaa aaagcccaac caaaaaggaa tacaacatcc cccacaagat
     4501 catcacagga cctttgatca atgcaacgat tgcgatgaac aaagtcagca atattagttt
     4561 ttgtgataac gttgcaacag tcattaatcc aaataaaatt aatgtgaacc aatgccaatg
     4621 ggactgctgt tgttctttac gggaaaaatc gacccggttg gataaataat ctgctaattt
     4681 cggataagaa cgcttaaaat ccataaactg ttcctccttc gtggaaaagg taggtttagt
     4741 atacgaaaaa taaaaaagaa atacatccgt cttaagaggg agtttttcac tgaaagtgga
     4801 gaaaaaagaa tggtaaatta aaatattctc agttatactg aaaattatac caaatttcaa
     4861 agaagaaaga ggatgggaat gaaaggcaaa ctaaaacgag aaatcaatct gtttggcgca
     4921 ttagctaccg ttatgggaac cgtgatcggt gcaggcgtct tcttcaaaac tgctgctgtt
     4981 actgctagta ctcagtctac aagtttgaca ttgctagctt ggcttttggg tggtttctta
     5041 acgatctgtg ctggattgac agtggctgaa ttagctacag caatcccgga aactggtgga
     5101 gctgtaaaat atattgaagc tgcgtatgga aaattgccca gctttttatt aggatgggcg
     5161 caaagcttga tttactttcc tgctaatatt gctgcattat cgattatctt tgcgacacaa
     5221 ttgacgaact tattacaatt atctaccgat tatcttttgt tgattgcagt gatcaccgct
     5281 gtttctgtga cagggttgaa tttgttaggg acaaaagtcg gtgcttctgt acaatcagtg
     5341 acgttgattg ttaaattaat accaattgct gtgattgtca tatggggatt attgacccca
     5401 ggacaaggaa ctgtccagtt atttccaatc gaagctggaa aagatgttac ttttgtcgaa
     5461 ggattgagca gtgcgttgtt agcaacgttg tttgcttatg acggctggtt aggtgtcggt
     5521 gcaatggcag gggaaatgaa acggccggaa aaagatttgc ctaaagcaat tattcttggt
     5581 ttgagttttg taacagtcgt ttatctattg atcaattttg tttttttgaa aactttgccg
     5641 attgatcatc ttgccggtaa tttgaatgca gcttctgaag catcagacgt catttttgga
     5701 ggaatcggtg gaaagctggt cactattggg atcttgatct cggtatacgg tgcattgaac
     5761 ggttatacac taactgggat ccgcgtgcct tatgcgatgg ctttagaaga cgagctacct
     5821 ttcagtaaac agctgacaaa gctttcaaag aagtttacgg ttccttatgt tcctgcggtt
     5881 ttccagttag cagtagcttg tattatgatg agccttggtt ctttcgactt tttaacagac
     5941 atgttgattt ttgtgatgtg gctattcagt ttactgattt ttatcggtgt ctttatttta
     6001 agaaaaaaag cgccggaatt gccacgtcca tataaagtac cactttatcc aatcgttccg
     6061 attattgcga ttctcggtgc tattttcatt ttaggtatga cgatgatgac gcaaacgaaa
     6121 ttagcattga tcggtatagg tgttaccttg ataggtatcc cagtctatta tcaaaaaaag
     6181 aaaaaacgct cagaagagta aaatatttca acaacagaca gaaaaagtac gaactaggtc
     6241 ctctagatct tcgtgctttt tctatttcaa taaaacaagt tcttctattt tgatttttgc
     6301 tacttctgca agtagtgctt atgtgctaaa gtaagaatga aaaggagaga taaacatgat
     6361 atttgattct catacccatt taaatgctga acagttcaat gaagatattc cagaaacgat
     6421 tcagcgagca caagaaatgg gggtaacgaa aatggcggtc gtgggcttcg atacgccaac
     6481 gattgaaaag tctttgcaat taagccatga ctatccaaat atatacagta ttatcggctg
     6541 gcatccgaca gaggctggca gttatacgaa agaaatcgaa aataaattac aagaacaatt
     6601 gactttacca aaggttgtag cattagggga aattggcttg gattatcatt ggatggaaga
     6661 cccgaaagaa gtccaagata aagtatttcg cagacagatt gctatcgcaa aagaaatgaa
     6721 cctaccaatc agtattcata ctagagaagc acttgaagac acgtatcaaa tcctaaaaga
     6781 agaagatgtt cgagatatcg gtggaatcat gcatagtttc agtggtgatt atgaatgggc
     6841 aaaacgattt cttgacttag ggatgcatat ttcatttagc ggtgtcgtca ctttcaaaaa
     6901 agcattagac gtccaagagg ctgcagcaaa tgtaccaatc gaacgattac ttgtggaaac
     6961 agatgcccct tatctggcac cagttccttt tagaggaaag cgaaatgaac caggctatac
     7021 tcgttataca gtagaaaaga ttgctgaact tcggaatctt ccgacagaag aagtggctgc
     7081 ccaaacatgg acaaatgcgc accgattatt tggtctaagc gaacatggat aagatgaaga
     7141 tccaagagat tatagtcgtt gaaggaaaag acgatacaag aaggctgcgg gaagtagttg
     7201 atgcagatac gatagaaaca atagggtctg caatcaatga agagatcctg atgcaaattg
     7261 aacatgccca agagactcgt ggagtgatcg tttttaccga tcctgatttt tcaggagaaa
     7321 aaataagaaa aatcattatg gaagctgttc ctcaggcaaa acatgctttt ttgccgcgca
     7381 cacaagctaa accaaagaaa aagggaagcc ttggtgtcga gcatgcaagt gatgctgcta
     7441 ttttagaagc attgaaaaag gtcgtgacgc cagacatttc ccaaacggct gtttctgaaa
     7501 tcactagaca agacctttta gactatggtt taatagctgg ggcacaagca aaagaaaaac
     7561 gagaaaaact aggtgacgag ttgcgcatcg gttacacgaa cggcaaacaa ttggaaaaac
     7621 gtttgaagat gtttcgtatt acgccgaaag aactcgccca agcaatgaaa atagtggagg
     7681 aacaacatga gtgaatatcg tgaaattgcg acaccctcta gaacaaaaga gattttattg
     7741 aaacatggtt tttcatttaa aaaaagttta ggacaaaatt ttctgactga accaaatatt
     7801 ttaaggaaaa tcgtagaaac tgcgcaaata gatgaacata cgaacgtgat cgaagttgga
     7861 ccaggaatcg gtgcattgac ggaacaatta gccaagcatg caaaacaagt cgtagcattt
     7921 gagatcgatg atcgtttgat ccctgtattg gctgatacga tgcaacccta tgacaatgtg
     7981 actattgtac atcaagatat tttaaagacc gatttgtcaa cagctgttag agaaacattt
     8041 catgaggagc ttccgttaaa agtcgtagcg aatttacctt actatattac gacaccgatc
     8101 atgatgcatt ttcttgaatc agatttggtt gtggatgaac tagtcgtcat gatgcaaaaa
     8161 gaagtagctg atcgtatctc tgctgaacca ggaacgaaag cttatggttc attatcgatt
     8221 gctgttcaat attatatgga agccagttta gcattcatcg taccaaaaac agtatttgtc
     8281 cctcagccaa atgtagattc agcgattttg aaactgacaa gaagagatat accggcagtc
     8341 gaagtgacag acgaaaaagc atttttccga ttgacaaaag cggcatttca gcaaagaaga
     8401 aaaacgcttt ggaataactt gcagcattcg tatggcaaag atgaccagac aaaagcatgg
     8461 ttagcaaaaa gcttggaaac agctggaatc gatccaaaac gtcgtgggga gactttgtca
     8521 ttacaagaat tcgccgcatt aagcaatgcg atgtcagaaa atatgcagta aaaaaagagg
     8581 ttgtgacaga agttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa
     8641 atagttcctc atgtttttcg tttgtttggg cttattaccg cagatgcaag cttttgaaca
     8701 ccgtttaaga aagaggttgt gggcctgccg tttaactcta agtcacaagg aacaatttca
     8761 aaaaacagct tctcatgttt ttgagttagt tggtcttatt acttgatgca agcttttgac
     8821 cactattatg ccgaacaagg agatgtgaca caaattttgt cacatctcct atttttgttt
     8881 cttgatcaaa aaattcttat acttgatact cacactcatt ttgtatggat ttagaaaaga
     8941 atatgtgtct tgacagttat tagtaagtga gttatactaa gtcgacattt atgtgtcaag
     9001 acatattagg agagagaaaa aatgagaaaa aattcagttc gaaaactaac gatttctgct
     9061 ttattgattg ggatgggggt cattatccca atggtcatgc ctaaaatcat gattccacca
     9121 gcttccttta ctttggcgtc tcatgtgcca ttatttattg cgatgttttt tacaccagga
     9181 gttgcagtgg ctgttgcgct aggtacgaca tttggtttct ttttaacaac gccggttatc
     9241 atcgcattgc gagcattgtc acatcttgtg tttgcgttga ttggggcttg gtacttgcaa
     9301 aagcatccga gtatcgtttt aaaaaatgga cagtttactt ttgctaattg gcgtttccaa
     9361 gggttcaatt ttgtgatcgg tgtgattcat tctttagcag aaatgctagt agtcagcatc
     9421 ttttacttta ttggtaatat gcctgaaaca tattattctc aaggatattt ttatacagta
     9481 ttcatcttga tggggattgg tgggcttatc cacagtttag ttgattataa tattgcttat
     9541 tttatagcag gaacactcag caaatatttt gatatccccg tatttacggc agcaaaaaaa
     9601 gaaaatcgga aagagtcgat tcaagggtac gcgaagaaaa cgacatatta gacatgatct
     9661 ctcaaaaaaa aaactctcat ctagtaatgg ataataaatc ctctaagatg agagtttttt
     9721 gtcctaaaaa gagctgcacc aacatcttct ggcacagctc taacaggggg caatttatgg
     9781 aagtttgatg acttgttctg tttctttatc aaagaagtgg cctttgctga tgttgaaggc
     9841 aaggtcgact atttcgcctg gtttatggaa atctcttgca tctacttttg agatgaactc
     9901 agtagaacca gtttttgtgt aaagcatcgt ttcagctcca agtaattcgg aaacgacaac
     9961 ttctgatttc actacggctt caggtgaagc ttcaagggct acttgttcac tgtggatgtc
    10021 ttctggacga ataccgaaga taacttcttt tccttcataa cctttttcaa ctaatacttt
    10081 gttttttcct tcaggaatac gaagcttaag cccatgtcca tctgtgataa caccattttt
    10141 caatgtcaca ttaaagaagt tcatggcagg agatccaata aagccggcaa cgaacatatt
    10201 gacgggtgta tcataaactt ctttcggtgt accgatttgt tggataaatc cgtctttcat
    10261 gataacgatt cggtcagcca tagtcattgc ttctgtctga tcgtgagtaa catagatggt
    10321 cgttgtttca agacgctggt gaagtttggc aatctcagca cgcatggcta cacgtaattt
    10381 agcatctaaa tttgataatg gctcatccat taagaagact tttgcatccc gaacgattgc
    10441 ccgtcccaat gccacacgtt ggcgttgtcc accagataaa gcagctggtt ttcgtttcaa
    10501 gtattctgtc agacctaaga tctctgctgc attgtccaca cgttttttga tgtctgcttt
    10561 atcatattta cgtaatttca agccaaaagc catattatca aaaacagtca tatgaggata
    10621 caatgcgtag ttttggaaaa ccatggcaat atcacggtct ttaggtgcca cgtcattcat
    10681 gacttttccg ccgatattta gttctccttc agagatatct tccagtcccg cgatcattcg
    10741 caaagtagtt gactttccac aaccggaagg accaacaaaa acgataaatt cacggtcttt
    10801 gattgataga ttaaaatcag ttacagaata attttctgca ttgtcatatt ttttatatac
    10861 gtttttcaga gccatttcta ccataatacg ttccacactt tcttttttag ttttattaac
    10921 tatttaaagt ataaatgaaa gcgttaacta acttcaatgt catgttgaac aagaattttt
    10981 tctttttttt gtcaatgtgc tagttttaag ctttaataaa tatccataag aaataaaaac
    11041 tgatacactg gagtaaataa gtatgttaac aatatcaaaa ggagtgtctc ttatgaaaat
    11101 cgctttgatc gctcatgacc gaaaaaaacc tatgatggtg aaattagcaa cagcgtataa
    11161 aacaatattg gaaaaacatg aactttttgc taccgggacg actgggcaga ggatcacgga
    11221 agcaaccggc ttgccgatcc atcggtttaa atccggaccg ttaggcgggg atcagcaaat
    11281 tggagccatg atttcggagg atcagttaga tttggtgatt tttcttcgag acccgctggc
    11341 tgcacagccc catgaaccag atgtaacagc acttatccgt ttatctgatg tctatgagat
    11401 tccgttagct acgaatatcg gaacagctga ggtgctacta agaggactgg aagccggctt
    11461 cctagatttt cgaagaatcg tccatgaaat agacaagcat ccactttcat tttgatggat
    11521 aagcgtatgg aaaaataacg tttaatgttc gcctatatgt agctataaaa gctaaacaaa
    11581 ctgataatat gcgatataat acgaacgtat tggataatat aaacaataat attagttttt
    11641 cgtatttgca gtaaatgtga aaatatgcta tagtttctgt gggaaaagat cccaaaaata
    11701 atacagagta gaaaataaag cgttaagtgc taagaggatg ggatgttgcc tcttggacga
    11761 aggacgtaat gttcgcggtt ttattttcgc attcgctgca tgatacgatg tagcagctct
    11821 taaaggagat gctaaaaatg aagaaacacc ggttagacgc acgtatgatt gctattatgg
    11881 gcttattgat tgcattgatg gtcactttgt cccgactggt agcaatcgag accccattta
    11941 ttaaaatcag tgtcacattt attccacaag tgatcatggg cattcttttt ggtccttttt
    12001 ggtcagggat aggcgcagtt ttagctgatt tagtaggaat ggccctcttc tcgaaatctg
    12061 cattctttat tggatttaca ttgaatgcat ttattgaagg agcaatctac ggattctttt
    12121 tctatcgaaa agagatcact tggaaaaatg ccattctggc tacgcttagt gtcacgctga
    12181 tcatcaactt atttttgaca ccattatggc ttgcgttgat gtaccatgtg ccattgttca
    12241 gctgggtcgt ttgggcgccc cgcctgttaa aaacagtaat atggttaccg attcaatcaa
    12301 ttgccattta ttacgtagga cgtagtattc cttacaaaaa aattttaaga agtttagcga
    12361 tccacgctaa ataaaaaaca agcagtcttc ccatcccaga agactgcttg tttttattgt
    12421 gctgtgaatt gtgcttgata gagccgtcgg taataaccat ctttttgaag cagctcatca
    12481 tgggtgccca tttcgacaat agctccctga tccatcacta atatctggtc cgcatttttg
    12541 attgtggaca ggcgatgggc aatcacaaaa ctggtttttc cttccatcat tgctaagaag
    12601 gcttgttgga tttttttctc tgtcaatgta tcgactgagc tggtagcttc atctaagatc
    12661 aacatagggg gattactgat catcgttcga gcaatcgtca acagttggcg ttgtccatct
    12721 gatatcttta acccttgacc gccaatctta gtatctaatt tttccggcaa acgttctaca
    12781 aattcataca tataagaggc ttttagggca tcattgattt ctgcgtcact tgcttccgga
    12841 ttcccaaaac gaagattttc tcgcaatgta ctgtcaaata gccaagtatc ttgtaacacc
    12901 attccaaaac ttttacgtaa tgtatcacgt tggatagagc ggatgtcatg gtcatcgact
    12961 gtaattgttc cttttgttgt gtcataaaaa cgcatcagca aattaacaag tgtggatttt
    13021 ccggcccctg tttttcctac tatagcaatg gtttgacctg gataagcagt aaaattgaaa
    13081 tcttcgatca aacgctgctt ggggtcataa gaaaaagaaa catgatcaaa agagactttt
    13141 cctttgatat ttttgggttc caaggcatag gcatctggca aatcaggctt ttcttctggc
    13201 tgatcgatca aatcaaatgc tcgttctaga ccagaaaaag cggtttgcag ttgtgtcgtg
    13261 attccagaaa gttcgataaa tggtttagaa aactgacttg agtagatcgt aaagctggaa
    13321 atcacaccaa cagtgattga cgaaccactc ttcaatgcca ataggccgcc aactaaacca
    13381 atcgataaat aagcaaggtg atctacaaaa cgagaagacg ggtttgtcaa ggaagaagaa
    13441 aattgtgccc gttgtccttt ttcatataga tcagcattta gcagttcaaa ttgctgttga
    13501 ctagcttctt cttgctgaaa agctttcacg attttctggt taccgattcg ttcggtcaca
    13561 aagcccgaga tatccccaat aatcctttgc tgtctatcga aatttgtttg tgaagcacga
    13621 gcaacgatcc aactcacaag gaaaataatt ggtgtagaac aaagaacgac caatgtcaga
    13681 agtggactta gacgcatcat aaaaataaac gaaagaatga tgattgccac tccagaaaat
    13741 aattgattga aggccgcaga aattgcaatg gaaatattgt ccatatcatt tgtaaatcga
    13801 ctgacgatat ttccgtggga gttttgatca taataacgaa gtggcaatcg attcagatga
    13861 gcaaatgcat cttttcttaa ttttgcaacg gataagtaag ctaaccgatt gcttaacact
    13921 tggatgagcc attgactgac tacgttgatt aaaacgatac caccgaatag aataagtaaa
    13981 tggaacagtc gattgaagcg gacctgtcct tctccaatca tttgatcgat actttgacca
    14041 atttgtaacg tcatcacaac tgttgcaatc ccattgatga ttcctagtat cacagctagc
    14101 caaatgtctt ttgcataggc agtaaggtaa ggaatgaatc ggcggagcgt ctgcaaggat
    14161 aattttttta ctttcataac tattcttcct cctgtgatgc gacgatttcc tgatattctg
    14221 ctgattgagc aagtaattct tcatgggtac cctgagcagc aatcttacct tgatccatca
    14281 ctaagatatg atgtgcttct tgaatagagc ggacacgttg ggagataata atcactgtac
    14341 tgccaagata agtctgtagc gccttacgca aatccaagtc tgtttgataa tccaacgcac
    14401 ttaaagagtc atctaaaatc agtaatgctg gcttggcaat caaagctctt gcaatcgtca
    14461 gtcgctgttt ttgtccgcca gagaaatttt tcccattttc catgactttt gtatctaaac
    14521 catttggaag ctgacggaca aattcttctg cctgagcgat tttcagagct tcccaacatt
    14581 ctttttctgt ggcgtctttc ttaccccatt gaaggttttc acgaatagtc ccggtaaata
    14641 gtacagaagt ttggggaaca agagcaattt gctgacggag atgatccagc tgccaagaac
    14701 gaacatccat tccgtccatt ataactgtac cggaactgac atcatagaaa cgcggaatca
    14761 attgtgtcaa agtcgttttc ccgcttccgg ttggaccaat gattccaagg actgtatttc
    14821 gcttcagctg aaatgtaata ttttggagag aaagaccaga atcaggagta taacggaagt
    14881 caacatggtc aaaagcgata attgcttcag aagaaaaatc gggagtagta ctgacctcag
    14941 cttcaagaat cgaattttct gtgtctagca cctctttcac ccgatttcct gaagcttcgg
    15001 cacgtgtgaa gatcacgacg aggtttgaaa caacgatcag tgccaaaagc atttgattca
    15061 tataattgat caaagcaaga acttgtcctt gttgcaagct accaatattt actttgatcc
    15121 cgccaactgt cagcaaacag atgatcccga cattcatgat caaggttgta gcaggtgata
    15181 atagggcaga gatattggaa acacgtaaat aattgttcgc tagatcattt gtgcttttat
    15241 cgaacttctc tgtttctttt tttgtctgcg caaatgcgcg gatgacacga acaccgctaa
    15301 gattctgact aacgtgttca ttgagctgat ctagtttttc ttgcactttt tggtagagag
    15361 gaacggtttt tttgatgata aaaaataaaa tgattgagaa aataggcaat aatgctaaga
    15421 aaaacagacc tacttcccag tcgatcacaa aagccatgac cactgacccg atacttaaaa
    15481 acggtgctct gatcaataaa cgaatgacca ttgctaaagc tagctgaagc tgattgatgt
    15541 cgtttgtcat tcgggtgatc aaggtatctg ttccaaaatg attcaactcg ttgtgagaga
    15601 aagtattgat ttttttgatt agctgattac gtaactctgt accaaatcct tgtgaagcta
    15661 ctgaagcata gtattggcaa atgatagcac aaatcagacc aatcacagac atagcgacca
    15721 tccataagcc catttcaatg atttttcctc ggtcattcat ttttagtcca ttatcgatca
    15781 aggaagccat cattaaaggc aggacaagtt cgaagacagc ttcaagaaat ttgaagaacg
    15841 ggcccaaaat gatttgctta cgatagtctt ttgcataacg taataactga atcatatgat
    15901 tcctcctatt atttatttgt ccacaattga aaaaacaagt actaccacat tgtagcttag
    15961 gaaatttaga atgaaaagag aacaagcctt ttcataaatg aaagttttat tatgaagaag
    16021 ctttagaaat tgaatagact atttttttta aaaaaaagaa aatgagaaaa catgccagtc
    16081 tcttcattca taggaacgtc tattttactt aatttttcta taaatgaatt ctgcataaaa
    16141 aatatatcaa gtaaatgttt atagatgaaa ctctatttac ttctttttta atttgttctt
    16201 gcaatctttt ttgctacgta atttttgtaa aaaagtgggt tgagagaaat ctaattgatt
    16261 ttcaaagaag gagtatgaaa atgagaaaaa tatttattcg tttattgtgg gtactatctt
    16321 agaggaataa ataatagtgg agaaaactat ggtttggcgc agattctatc aggtttgatg
    16381 gaacgaagac aacctcccga catcaagtca aaagctactt gagattttga tctgaaaata
    16441 aaaaaagaaa acaaggtagg aacatcaatg tttctacctt gttttcgtaa tcaatgggaa
    16501 aaaactaaga gtggtgtacg taatcaataa aaaggatggt gacaacagta cctctttact
    16561 ctctgaaagc atcataactc gtttttcctc attatgccaa taaattgttg ttataccaca
    16621 tataaggatt tgtaatagct aaaaacagac aggaaagttg aaatctgtga atcttatttt
    16681 gtatggaagg atttatagaa cgcaaaaatc aagataaaga tgaataaaaa tcctgtttcg
    16741 gctatatatt gcgtatctac gccaataaaa cgagtttgtt ctgtcatagc catataaagc
    16801 aaaggcaaaa atacaactac agcgagataa gatccgatga tttctcgaaa agttttccag
    16861 gaagtatgtt tcctgttttt atatttatcc gatttcattg aatagtcata gcctccttat
    16921 tctttcatat gttgaaattc cagtataaaa actggaagga actgtacgtt ttttagaata
    16981 aaaattataa gggataagta ggctgctgtc tataataaga tatatttttc aattctttat
    17041 taaagatttt attgacaaaa tgaatccgtt ttctatgatg gaggaggggt gaataagttg
    17101 ttgaagaagg aaattttatg ttacttagag aaccagacag cctttttcga tttagaacat
    17161 atgaacgagg tctttacagc acaaaggtta gctgatcatt ttggggtaaa aagaaacaca
    17221 gtcagtcatt atttgaacca gttaaatgat gagcaactac tagtcaaaat caattctcga
    17281 ccagtgattt atttccacaa agaagctttt gaaaaacaat tttttaagtt acgcacgaat
    17341 ttttattttt ctatcgatga tctcaaagag gaacagcctt ttttcgcgca accaaaagac
    17401 ttattctctt ttatgatcgg atacgacgcc agtttgaaag aaagtatcga acaaatcaaa
    17461 acagctcttt actatccaga tggcggatta ccacttttga ttacaggcga aagtggcaca
    17521 ggtaaaagtt atttagttaa tttggtctat cagtattgtc tgcttcatga tctgctagaa
    17581 gattctgcac cattcatcac ttttaattgt gcacaatatg cagataatcc tgaacttttg
    17641 actagcaatt tgtttggaca tgttaaggga gcgtacactg gtgcagaaga aaataaaaaa
    17701 ggggcttttg aagcagcaga tggtgggatc ttgtttttag acgaggtaca tcgcttaaca
    17761 ccagaaggtc aggaaaaact gttcacctat cttgatcaag gtgtgattta tcgtatggga
    17821 gaacctaatt tgtcacgccg gatcaaaaca cgtctctttt ttgctacgac tgaagagatt
    17881 actagtcatt tcttaacaac tttcattcga agaataccta tccgaatcga actacctgca
    17941 cttaatcagc gtagtcgtaa tgaacggcta gaactgattt actctttttt tctcgaagaa
    18001 caaagaaaaa tggggagccc tttgtcagtc agtggaccag ctttgtcact tttaacaagt
    18061 cagaaattat ccggaaacat aggagagctg aaaaatatcg tcaaagtttc agcagcaaaa
    18121 gcatatgctg aacagcgtga acagcctgaa atccatgtca cgatccatca tttgcaaaaa
    18181 gaactacttg cgcagcctat tactaaaaat acagcacagc aaggaatcta tattacgcaa
    18241 gaccagacct tagagcaatt aatggagaag caacagcccg aacagcagcg aatcgttaaa
    18301 agttttgagc aaatcctaat tgatttcaag aaaaataact gtctgctata ttcttgcgaa
    18361 gtaaaattaa agcaagaagt gattcaatta tttgattttt tgctgtttga gaccagtaga
    18421 caagaaaaac acgagctgct ggtttattgg acacaatcta tccgagagac ctttcgacaa
    18481 atggaaactg cctatcaaat caaattcgat ggaaacagtg tctatgcctt gagttactat
    18541 ctctatcagc gaagcactat caaatggtta ccggaagaac atgatattat ccaactaatc
    18601 aaagaattag aacaacaagt ttctcagtct tatccatcta gttatcacta tgtccaacga
    18661 attctggaat taagtaagat caaattagat attgaagaca caagtatgga tcggatttta
    18721 ctgacgatct atctaaaaaa agcgaaatgg tcaaaagaaa aacgactgcc aaaagcgatg
    18781 attgctgctc acggttatgc aactgctagc agtatggcaa atgtagtaaa tcgtttatta
    18841 caagaggatc tatttgaatc atttgatatg ccactagatg tcacaccaca gcagattgct
    18901 tcagaaatcc ttgattattg cgaaaacagc gatgtttcaa atggattgat catattagta
    18961 gacatgggat ctctgaaaga aatccatcag ttttttaaaa aacagttatc cgtaccgctt
    19021 ttgattttga ataatgtgac gacaccttta gcaatcacag taggggaatg cctgcaaaaa
    19081 aatgtatcat tagaagagat agcagaagag actgttcgac agatccagcc agaatggcga
    19141 ctgctctatc cagaggaaaa caaacccaaa gcactcatta ctacttgctt cactggaatc
    19201 ggtacggcgg tccacttaag tgaactgcta gaaaaaagct tacctacggc ttgtcagttg
    19261 aaaatcatcc catatgaata tcagcaatta aaagataaga aaaacagtga cccattattt
    19321 tccatatacg aagtcgtagg aatgattggc accacagatc ctgatatcac caatatcgac
    19381 tatctttcat tagaagacct catctcgggg gaaaagatgt ctgtactagc tgaatggttg
    19441 gacactacta tgaatgcttc agagaaggaa atattcaatc agcgcatcat tcgtaatttt
    19501 tcattggaaa aagtactgga ttccgtgact attctagata cagagaaggt gatgggagaa
    19561 atcgatcatt ttatgagaga attagaggtg cagttgaatc gaagcatcag caatcccaaa
    19621 aaattagcgt tgtatgtcca tgtgagctgt ctcattgaac gattgatccg acaaatgcca
    19681 atcgaaacct atcaaggatt agagaaatgg aagcagtgtc aaaaagaagg gttatctgct
    19741 attaaatctg cgtttagtgt cattgaagag cattatagtg tcatgatccc caattctgag
    19801 attgcctata tctatgatat tttgagtgaa gatacagagt ttctctcgat agaagaagaa
    19861 ttttgaacat aagcaagttg ttgccact
//
LOCUS       DAIGQM010000056        19188 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.057, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000056 DAIGQM010000000
VERSION     DAIGQM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.057"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            26..463
                     /locus_tag="NOA48_002020"
     CDS             26..463
                     /locus_tag="NOA48_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790271.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            558..1442
                     /locus_tag="NOA48_002021"
     CDS             558..1442
                     /locus_tag="NOA48_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0790272.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1666..4833
                     /locus_tag="NOA48_002022"
     CDS             1666..4833
                     /locus_tag="NOA48_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790273.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4853..5398
                     /locus_tag="NOA48_002023"
     CDS             4853..5398
                     /locus_tag="NOA48_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HCI0790274.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5426..5881
                     /locus_tag="NOA48_002024"
     CDS             5426..5881
                     /locus_tag="NOA48_002024"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HCI0790275.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            5878..6636
                     /locus_tag="NOA48_002025"
     CDS             5878..6636
                     /locus_tag="NOA48_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0790276.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(6722..7462)
                     /locus_tag="NOA48_002026"
     CDS             complement(6722..7462)
                     /locus_tag="NOA48_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790277.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            7523..8776
                     /locus_tag="NOA48_002027"
     CDS             7523..8776
                     /locus_tag="NOA48_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0790278.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9098..9325
                     /locus_tag="NOA48_002028"
     CDS             9098..9325
                     /locus_tag="NOA48_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0790279.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            9448..9774
                     /locus_tag="NOA48_002029"
     CDS             9448..9774
                     /locus_tag="NOA48_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0790280.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            9842..10555
                     /locus_tag="NOA48_002030"
     CDS             9842..10555
                     /locus_tag="NOA48_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0790281.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            10865..11716
                     /locus_tag="NOA48_002031"
     CDS             10865..11716
                     /locus_tag="NOA48_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0790282.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            11837..13702
                     /locus_tag="NOA48_002032"
     CDS             11837..13702
                     /locus_tag="NOA48_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0790283.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            13750..15159
                     /locus_tag="NOA48_002033"
     CDS             13750..15159
                     /locus_tag="NOA48_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCI0790284.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            15267..15968
                     /locus_tag="NOA48_002034"
     CDS             15267..15968
                     /locus_tag="NOA48_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0790285.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            16127..16606
                     /locus_tag="NOA48_002035"
                     /pseudo
     CDS             16127..16606
                     /locus_tag="NOA48_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            17454..18029
                     /locus_tag="NOA48_002036"
     CDS             17454..18029
                     /locus_tag="NOA48_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCI0790286.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            18029..18469
                     /locus_tag="NOA48_002037"
     CDS             18029..18469
                     /locus_tag="NOA48_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0790287.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            18485..19186
                     /locus_tag="NOA48_002038"
     CDS             18485..19186
                     /locus_tag="NOA48_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0790288.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         6423 a         3198 c         4123 g         5444 t
ORIGIN      
        1 aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt tatttctaga
       61 agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa gtacaatgga
      121 tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca cactaattat
      181 agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac atcaagagtt
      241 tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca aaaagtggaa
      301 gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta agatttttac
      361 tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg ttttaatttt
      421 cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac
      481 agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa gaaatcaatc
      541 agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt tcaggcggtg
      601 aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg tttgatgaag
      661 tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta
      721 cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac gaaggaatca
      781 gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg ggtacggtga
      841 atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc aatcattttt
      901 cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat tttatgaatg
      961 tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag aagaagacga
     1021 aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc acacaatcct
     1081 actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt accttgctga
     1141 taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca aaagtggatg
     1201 atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg cttaaaacat
     1261 tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac cttacttgtg
     1321 agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt gatggagatg
     1381 aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag gtttattgtt
     1441 aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg gataagggac
     1501 tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta cacctaatag
     1561 aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga aatagattaa
     1621 aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta
     1681 aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac atccgttttt
     1741 gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt tgacaagact
     1801 actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga ggcttctact
     1861 aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga acaaacgtct
     1921 gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag cgaagctgcc
     1981 acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat ccgactgatt
     2041 cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat tgattttggt
     2101 ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc tcagtcgatc
     2161 gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc aaatatcgat
     2221 ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata tcattttacg
     2281 ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt aggactgatt
     2341 tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga tgtccaacca
     2401 gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag ctatcaattg
     2461 aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta cggttttcta
     2521 gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat cttaagcggt
     2581 tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg agaggcagtc
     2641 gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga attttcggta
     2701 aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat gagaggttca
     2761 ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc aactacgggc
     2821 ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg acaaatctcg
     2881 gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa
     2941 ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa gcagagtggg
     3001 cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac caatggaggc
     3061 tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact caatcaagga
     3121 aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg ttcagctgat
     3181 tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg agcaactgta
     3241 gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta tttagtcatg
     3301 gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt gaatgtggac
     3361 ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga gaccaatggc
     3421 ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc ccattcagaa
     3481 atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga cccggattat
     3541 ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt cgtatcaagc
     3601 cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa aaattataat
     3661 cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc aacgaatgca
     3721 gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat
     3781 gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac gacgaaatca
     3841 tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg ggcaggatat
     3901 aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc caatgatgag
     3961 agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa
     4021 gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc tgaacctgct
     4081 aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac aggtgaagca
     4141 ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac tattgatgat
     4201 acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga tgtattagaa
     4261 attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa caagccaagt
     4321 accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta tcatgatgcc
     4381 ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt tcttgcccct
     4441 tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc atttggccaa
     4501 atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa tccgtggatc
     4561 ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat gcaggatgtc
     4621 ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc
     4681 agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa taacggtcgg
     4741 gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc agcagagata
     4801 acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat tgatgaatcg
     4861 aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc tccttggatt
     4921 catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag attttgaatt
     4981 accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg agcctgggaa
     5041 aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa cagttgagac
     5101 attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag
     5161 taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag tgggagaaat
     5221 aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc cagaaaaaga
     5281 gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga acgtttctaa
     5341 caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa
     5401 tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga
     5461 tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata tgttcggctt
     5521 gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt caataaaaaa
     5581 agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat tagaaggaaa
     5641 aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg
     5701 gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga atgaaaagga
     5761 tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac ttgttggagt
     5821 cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga aaaagaaatg
     5881 aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg tacacaaagt
     5941 gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt gaccaaacca
     6001 gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa tgatcctgat
     6061 actcctttta cacctgacga accaaatcag ggaacatccg gattactgac gattgaccaa
     6121 gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt atatgctgca
     6181 ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt cgtacaagta
     6241 acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac agaatttatt
     6301 ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa aaacgccgtg
     6361 attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg aactggcgct
     6421 gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg agcaaatgaa
     6481 gggattggca catggattta ttcattagga gagaatgtgg aacaagggag acaatcagtg
     6541 gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac attcacatgg
     6601 tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga tttcagggag
     6661 tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca gctcttattc
     6721 atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt tcaaagatct
     6781 ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga gcagaatcaa
     6841 ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag taagcatact
     6901 tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct tctgtagttg
     6961 ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa atttcccgag
     7021 gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca tttacgatct
     7081 gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat aaattcctgt
     7141 cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact gcaaaattcg
     7201 tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt tgttcggcga
     7261 catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca tcgtgattat
     7321 caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc tgcacgatat
     7381 tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac tggttatctt
     7441 ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg tacattttga
     7501 aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga cctttacttt
     7561 gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa aaaacagctt
     7621 tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag tgagctttcc
     7681 ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa acctgtttat
     7741 cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt ttctggtttt
     7801 tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt ttgcactact
     7861 tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga gatttctcaa
     7921 cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt tattaagctg
     7981 gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt atctgcttct
     8041 atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta tgttgatcag
     8101 tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa taaatgaaga
     8161 atattaccat catctagagg aattcaaaca tgattataaa agtctactgt tttcattaaa
     8221 aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat tagaagatca
     8281 ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg tatccccagc
     8341 tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa tcccgatcca
     8401 agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt ttattcgctg
     8461 tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga gtccgattac
     8521 gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca aggcaaatcc
     8581 aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa aaaatggcgg
     8641 gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag aactaaaaat
     8701 cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat ctagaaagag
     8761 caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta cacggagata
     8821 gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg tcacccttct
     8881 gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta gtattagtac
     8941 gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc acgatcgtca
     9001 aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct tattttaggc
     9061 gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc agttaagaga
     9121 gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc ctaaagtaga
     9181 gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt tgtctgtttg
     9241 ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc tactgcatac
     9301 acatggtggc tacctaaatt attgattttc tatgacattt attttaaata aaagaaaaca
     9361 ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga ttaatcaagt
     9421 aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa ccagtttaga
     9481 gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc tatttctttg
     9541 gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt aaaagaaaca
     9601 caattagaac gaatcaaaga agaactggca gatgtattga tctattcata catgatggca
     9661 gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa aaataatttg
     9721 aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt gtagaaatgt
     9781 gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg agggagagaa
     9841 aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt tcctcttgtt
     9901 attagtagga ctagctttga ttttcaatga acagatcaag gattattttg tcagagagac
     9961 aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga ataacgataa
    10021 agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg tcatgaggtc
    10081 gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt cagtttcaat
    10141 caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag caggaacatt
    10201 atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc gtgcaacgaa
    10261 ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga tctatttgac
    10321 agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg ctcctacaga
    10381 tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta cttgtggcga
    10441 catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta catcgataaa
    10501 agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat tttaggatac
    10561 tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat aaggaaaaac
    10621 caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt tgttttctag
    10681 atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata aataaaaatt
    10741 cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg caaaaccaga
    10801 attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga gagggcgaag
    10861 caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa atggattcgg
    10921 ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg gggacgagat
    10981 ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta aaaaccaatt
    11041 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    11101 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    11161 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    11221 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    11281 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    11341 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    11401 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    11461 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    11521 ggaaggatct gacgaacaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    11581 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    11641 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    11701 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    11761 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    11821 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    11881 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    11941 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    12001 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    12061 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    12121 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    12181 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    12241 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    12301 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    12361 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    12421 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    12481 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    12541 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    12601 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    12661 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    12721 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    12781 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    12841 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    12901 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    12961 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    13021 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    13081 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    13141 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    13201 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    13261 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    13321 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    13381 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    13441 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    13501 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    13561 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    13621 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    13681 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    13741 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    13801 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    13861 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    13921 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    13981 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    14041 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    14101 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    14161 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    14221 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    14281 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    14341 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    14401 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    14461 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    14521 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    14581 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    14641 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    14701 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    14761 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    14821 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    14881 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    14941 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    15001 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    15061 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    15121 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    15181 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    15241 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    15301 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    15361 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    15421 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    15481 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    15541 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    15601 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    15661 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    15721 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    15781 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    15841 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    15901 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    15961 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    16021 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    16081 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    16141 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    16201 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    16261 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    16321 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    16381 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    16441 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    16501 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    16561 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    16621 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    16681 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    16741 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    16801 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    16861 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    16921 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    16981 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    17041 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    17101 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    17161 atgatttttt cgttaataac agaaacaagt atttgttgtt taaaataata cacgttattg
    17221 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    17281 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    17341 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    17401 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    17461 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    17521 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    17581 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    17641 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    17701 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    17761 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    17821 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    17881 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    17941 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    18001 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    18061 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    18121 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    18181 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    18241 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    18301 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    18361 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    18421 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    18481 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    18541 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    18601 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    18661 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    18721 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    18781 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    18841 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    18901 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    18961 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    19021 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    19081 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    19141 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaa
//
LOCUS       DAIGQM010000057        18897 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.058, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000057 DAIGQM010000000
VERSION     DAIGQM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.058"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..2232)
                     /locus_tag="NOA48_002039"
     CDS             complement(<1..2232)
                     /locus_tag="NOA48_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790289.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="NOA48_002040"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="NOA48_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            complement(4140..4901)
                     /locus_tag="NOA48_002041"
     CDS             complement(4140..4901)
                     /locus_tag="NOA48_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0790290.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            5001..6722
                     /locus_tag="NOA48_002042"
     CDS             5001..6722
                     /locus_tag="NOA48_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790291.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLTGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            6737..8521
                     /locus_tag="NOA48_002043"
     CDS             6737..8521
                     /locus_tag="NOA48_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790292.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8902..10455)
                     /locus_tag="NOA48_002044"
     CDS             complement(8902..10455)
                     /locus_tag="NOA48_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0790293.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10803..13217)
                     /locus_tag="NOA48_002045"
     CDS             complement(10803..13217)
                     /locus_tag="NOA48_002045"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCI0790294.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     misc_binding    complement(13368..13574)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(13644..15662)
                     /locus_tag="NOA48_002046"
     CDS             complement(13644..15662)
                     /locus_tag="NOA48_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0790295.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            16032..16688
                     /locus_tag="NOA48_002047"
     CDS             16032..16688
                     /locus_tag="NOA48_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0790296.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            16688..17644
                     /locus_tag="NOA48_002048"
     CDS             16688..17644
                     /locus_tag="NOA48_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCI0790297.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            17644..18210
                     /locus_tag="NOA48_002049"
     CDS             17644..18210
                     /locus_tag="NOA48_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0790298.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            18646..18876
                     /locus_tag="NOA48_002050"
     CDS             18646..18876
                     /locus_tag="NOA48_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790299.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
BASE COUNT         5554 a         3786 c         3353 g         6204 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatcactac cagtcaactt ctataatatt
     3481 accaaataac aaactaacta tccatcaata acgtgtttta ttttttaaaa tttctataaa
     3541 aaaaacaatc attcttaaaa agaatatata aaaataacaa taacctttgt gatttttctt
     3601 gtttgaagaa tgttagaaga aaaatctcta aatacttata attattttat aagcaaaaaa
     3661 atgctatcgg tagtatcacc gatagctgag gaaagtcaca gtagggacta tttgattaaa
     3721 aaatatgttt attcaatcca tctatttatt tttgccttat taacatattg taataatgta
     3781 agcaacaatg tattttaagt gtaatgcttt tatgcaccta tttaatttat cattctcatc
     3841 tgatacaatc tcactcataa caatatgaat ttttcttctc attagtctca gttcaccatg
     3901 aattatacat aacacccaat acaattattt ttccatactt ttttaagagg acaattacat
     3961 cgtatatatc gctaagaatt gcaaccattc catttttaaa gacatatttc ctctaaaaaa
     4021 ctaaaattct atctatccac gactaataat cccccacatt aaacccgtaa tcgaaccaga
     4081 aaatttttct ttataactaa aacaaccatc attttcgagt tatcttaaac acatatttcc
     4141 tattttttca tttctatcca tgcatgataa tattcagttc tgatattgtt ttcatccgta
     4201 ttcgtcaata gatactggcc gatcacttct cctgttttcc atcctttttc atacattctt
     4261 tctctgattt ctaaaatatt attacgttcc gcatggttca tctcggattt caataagaat
     4321 cgacgataaa cagccgtatc ttttttctcc caaatcacgt cttgagtaaa taaatgtact
     4381 tcactagggt cgataaaaaa tccatacatc gtctgtgaac tggaagctgg catactcatc
     4441 atcccaaagc ttgaatagtt aggtagaaat tttttgattt ccacaatatc ttcaaactcc
     4501 gttgagatca tacagtcaaa agggatctct tctacaggaa attcttcctc gtttgtatcg
     4561 atcatcaatt tcaactgttt tttttgctcc cttatctctt tttgtttttg tttcatcacc
     4621 accagttctt tatggattct tctttctgtt tcatcaagtg tctcatataa ctccgtcaat
     4681 gtttttccat ataaattctt catctgtttg ataggtatat ctaattttct ataaaaaacg
     4741 atatcataaa gcataaaaat atcatcgata tcaaacaatc gataatcatt ctcttcttgt
     4801 ctacttgaac ggattaatcc ttgttcatcc caatagcgga tcgttgattt tggcaaatca
     4861 aatagttccg atacttggcc aatcgtatac atttttttca ttttttctca cctctttttc
     4921 agtttattct tttttctatt gaccttcaag ttacttgaag gtatagaatc gaaaagtatc
     4981 aggaaaaaag gaggaataat atgtctatct taaaaacatt cttacagaaa aacaaaggac
     5041 tcgctctcct tacctttgtg atgatctgtt tagaaatcgc cggtacatta ggtgtaccaa
     5101 aattagtagc aaagctgatc gacacaggta tagcaagtgg cgaagcctca gttataaaaa
     5161 aaattggagt tgaaatgctg cttgtagcgt ttctaggaac aatcgctgca gttgcctcta
     5221 gttacttttc agcattggct tccgctaggt ttggattcca aacgcgggag aaatatttcc
     5281 gtaaattcca acagctgtca atgaaggata tcagtcgttt tagttctgga tctcttttga
     5341 caagaatgac gaatgatgtc gataatgtcc agcaaatgat tgttttattt tgccaaatga
     5401 tcttaccagc accggttatt tgcgttttca ccattctcat gatgtttcgt tattctctat
     5461 tactaacatg ggttacattg atctctgttg ttttttatgt atggattgtt tatcgactga
     5521 tgaaacgagg ggcaccttta tctttgagta tccagccaaa aatggatcgg atcaccatca
     5581 cattgagaga attctttact gggattaata tgatccgtgc ctttgataat caatcatatg
     5641 aagaaaagcg aacgaataag agctttgctg actatgctaa tcaaatgatc aaagtgaacc
     5701 gaatatttgc ttgggtcact ccaattgctt ttttgctcac gggaatcgtt tatgcttcta
     5761 ttttgtggtt tggcggaaat cttgtagcag aaggagcatt acaaatcggt gtcgtgactg
     5821 ctgtagtcga atactctatg ctgacacttg cttacttgat gatcgcagct atggtattgg
     5881 tcattatccc taaatcgttt gcctcattac gacggataga agaaatactg caagcagaga
     5941 tcgaaattga ggaagagacg atcaaaacag tagctgaacc aacctttgat cagacaaatg
     6001 cagctgcttt tgaacatgtc acatttaaat atactgaaat ctctgatcca gttctagaag
     6061 atattgattt cacaatacct aaaggaaaaa caacagcgat cgttggcggg accggatctg
     6121 gaaaaagtag tttggcgaaa cttctcttga gacttagtga ccctacgata ggaaaagtaa
     6181 cccttggtgg tattcctctt actcaaatga ctcaagaaca gatccgctcc cacatcagtt
     6241 atgtccctca gaaggctttc ttattcagcg ggacaatttt aagcaacttg cagatgggaa
     6301 atgaatatgc ctcaacagaa gagttgtcta aagcgatcaa gatcgctcaa ttagaagaac
     6361 tagtggacac ccttcctgac ggattggaca gctttgttgc tcaaggcggt tctaattatt
     6421 cagggggcca gaaacagcgg atatgtattg ctcgagcgtt gatcaaacca gcagagatct
     6481 atgtattcga tgatagtttc tccgctttag actataaaac agatgcagca ttaagagcag
     6541 cccttcataa acacatgtcg gagaaaactc tcgtgattgt tgctcaacgc ctcagtacaa
     6601 tccaacaagc agataacatc attgttttag atgaaggaaa aatcgttgga caaggtactc
     6661 atgaagaact actgtctaat tgccaaactt atcaggagtt tgcaaaatca caaggaatat
     6721 agaaagaagg gatacgatgg aaaagaaaaa aacgttgaac acgcgtgctt tgatacgttt
     6781 ttggaaaatg atcaaacctg aacataaata tttttacgga ttgtttctat gcagtttatt
     6841 cgggaaccta ttagtcgtag ccatgccctt gatcatggga atcgggatcg atgatctctt
     6901 atcagaaata agaaaaacag gtattggaca gctttctttc agtgatatca aacaagcatt
     6961 gttgttccct gtcttattgc tgatcggctg ttcagtctta agcagcatca cttcatttat
     7021 tcaggaacgg acaatggcag cgttaagcga aaagatcaca ttgagggtgc gaaaagaaat
     7081 cacaaaaaaa ttcaaaacat taccgatgtc gttttttgac aatcatcaag taggtgacat
     7141 cattagtcgg acaactaccg gtctcaatca actttctcaa gtgttattga caggtatcaa
     7201 tcaatttttt acttctgtcg taacaatagc tgctgctggt ctgatgctgt tttatatcga
     7261 aagcaagctt actttgctcg tcttattgct gatcgttggc agttcaattg ttacaactaa
     7321 gattgcgaac aaaaacaaac agatttctga acagaatcag tatgaactgg gtgttttaaa
     7381 taatcgaatg gaagaaatct tagctggtaa tctagtggtc aaaacattca atcagcaagc
     7441 tcatgcagaa gctgctatac acgaagtaaa taaaaagcaa tacaacgctt ttaaacgtgc
     7501 tcaatttatg aactgtgcta tctatccggc cattcgtttc attaatcaac tcgccttcat
     7561 cataagtgcg gtattcggtg ctatgcttgt tctatcaggt ggtgtgacga tcggcttctt
     7621 acaagcttat cttcagtaca tcaatcagat ttctgaacca atttctaccg cttcttatgt
     7681 gatcaactcg atccaatccg caatggcagc aatcgatagg atatttgaga tattagatga
     7741 aacagatgaa attccagacc ttccagatgc aagactttta gaacaaccga aaggaaaaat
     7801 agctttcaaa aatgtacagt ttggttacac atcagataaa atattgatga atcaagtcga
     7861 tttttcagta aagccaaaac aaacggtagc gatcgttggt ccaactggtg caggaaaaac
     7921 gactttagtc aatctgctga tgcgttttta tgaactgaat aaaggaaaga tcgaattcga
     7981 cggtcttgat attaccaagc tttcacgtgg agaactacgt cgttcttttg ggatggtttt
     8041 acaaaatacc tggctgtttg aaggaacggt agctgataat atcgcctacg ggaaaatgga
     8101 tgccacaaga gaacaaatta tcgaagcggc tgaaatcgca caatgtgatc actttattcg
     8161 aacactgcca gacggatatg atacgatcat ttctagcgaa aacggcacgt tatctcaagg
     8221 acagcaacaa ttattgacaa ttgctcgagt cattctagcg aatcctcctg tcgttatttt
     8281 agatgaagca acttctagcg tagatacacg aacagaagca ttgattcagc aagcaatgga
     8341 agctgtgaca aaagatagga caagttttgt gattgcacac cgtttgtcaa cgattgaaaa
     8401 tgcagacatg atccttgtaa tgaagaatgg cgatatcgtc gaaaaaggaa cacattctga
     8461 actactccaa tcaccaacgc tttatgccag tctttataat agtcaatttc agatagcgta
     8521 acaaacatta tctaaaaagc tatcgatcat gtatgattag tccatgatcg atagcttttt
     8581 taaatgtact agtggtgcca ctagaaacac aaagaataat actaatgata ctttttggat
     8641 agctccttca gtttcgttcg gtaagtagtg acaaaagact tgtcacaatc cctttttacg
     8701 aataaacggt gttcaagaga caacctatcg gcaataagac acgatcttgt aaaatacgag
     8761 aagctatact tcaaaatcgc ttcttgttgc tcttgtcaac tccgaatcac gagttacact
     8821 attcaacaaa tatgagaagc tgttttttga atttgtttct tgtgactcgg tgctgaacgt
     8881 caggctcaca atctctcttc tttaatctcc ttgttctact tgcgatagtt gctgaacgaa
     8941 ttgccatgtt tccccgttat cagttgaacg gaagaggcag gcaaacattt tccctgcatc
     9001 gattggtcct tttttcaaca aataaaattt tgtctctaac gtattcgcgc ttatttgagt
     9061 aacttcattt ggtgattgaa aaagatctat cccccctgtc tgatagtttt ccggaatcga
     9121 cagaactgat tctttgaatg agcgtcctcc gttgtttgta taaaacaaac tttcacgtgt
     9181 cgaaacaaaa cctaaagaag ttgtaacgaa gctgacattt tgtactggct gattgatcat
     9241 tgtacttcca ctttttatcc aagtgattcc gccatccata gtagtgtaaa tgtacaaagt
     9301 ttctgcagac atcccactgg ctgatgtaca gataaataga ccatcgttgc cataaaatac
     9361 cgcttttcga taacgtatcg gctgaactga ttgggtgata atagacgttt gccatgtttt
     9421 accattatct cttgaagtca gcagacgtac atcatcccca gaagaataga taaaccatga
     9481 gaaatcggcg gaaatatcat atgtgttgtc catccaataa ccttcaggaa tcagccccgt
     9541 tgtcagggtg tattcgccaa aacgcaacca ttgcgaatca atcggcacaa atacccaatt
     9601 agcaccacta tctgttgtca tatagagaga gtgcgtctct gtatcaagtt tgagatcatt
     9661 tatcttttgt gttgtcaaat ttaccttttg cttaggatca gctaacaacc cttcatttgt
     9721 cttttgtata tgcgtatcgt tagttgagtt cattgtcatg tgagaagcag catttatatg
     9781 agaagacatt tttggctgag tgtatctccc ataatagatt gttccagcta aaagaatgag
     9841 gaaaaaacca gtgactaatg tactcatctt agttgtcagg tatccaccag gcgaagactg
     9901 gcttttttcc catctgggtt cgttttctag taaaaaaata tggaatgtgt tcattccgaa
     9961 ttttgatttg ctttcgccta agtagatagg taaatcatca agtgatctca gcaataactg
    10021 gcaatcactt ttttgtatcc gaaaagcttg actcgtcgaa gtcttctcaa aataaagata
    10081 gtcatcatct tgagaagttg gtttattatg taaaaactgt tgtgctcttt gactaagcca
    10141 ttgatcgaaa tgacgcgaca attgatggta acggagccaa ataagtagaa gaaaaacaat
    10201 aagcacaaca attgttattc cgccaactcc ccacgaaaag tgatacaaat tatttaattt
    10261 ttgcatccct tcagctgaac ggactactgc actcatatgg cgatatagga acgatacagc
    10321 tccgaaaaaa agcaaaccag agaaaaatac taagcttaaa agcttgaaca ttattctttt
    10381 cgctcttttt ttcgctttct cgataatttt ttgtttagct gataatactt cgataataaa
    10441 tagttcttga tccatttgtc tctccttttc tcatacttca ttcattatgc gtcaaaatcc
    10501 atacaatcac tagtcccact aataaaaaat ttatgaattt ggtatgtact ctcaatttca
    10561 ggtagtttat acatcaaaaa atactaagat taatagacaa aaatttgatg attacagaga
    10621 tctcttacaa gaccattcag aagaaaaaga cattgaacgt gtttgagaac atgaaaatca
    10681 aaaccttttt gatcaatcaa ttaatcaatt tgaaataaca aaaaatctga gacagaatga
    10741 agttcattct ggcccagatt tgattttgca caactcatca gtccttattg acaaagagcc
    10801 aattaattag caacgatatt gactaacttg tttggtaccg caataacttt tctgactgtt
    10861 ttgccttcaa tatattcttg cactatttca ttggctaatg ctgctttttc tagctcatct
    10921 tttcctaagt ctcggggaac attgcttttc gcacgaactt taccgtttac ttggaaaaca
    10981 acttctactt cgtcttcaac aagtgctgct tcatcgtatg ttggccatgg tgcgtaagaa
    11041 ataccaccat catttccaag gattgcccat agttcttcac ccatgtgagg agcaatcggt
    11101 gcgagtagtt gaacaaatcc ttcgatatat tcataaggca gagcgtccac tttataggct
    11161 tcattgataa agaccatcaa ttgggagatt gctgtattga aatgaagatt ttcatagtct
    11221 tctgtcactt ttttcactgt ttgatgatac actttatcaa gcttgccatc attcaatgta
    11281 gtgatacggt cacgcatttt attgttctca tcaacgatca aacgccatac acgatccaag
    11341 aatttacggc ttccttctaa gccattttcg ctccaagcaa tcgaagcatc taatggcccc
    11401 atgaacattt cgtacatgcg cagtgtatct gcaccgtaag tttcgaccac atcatcagga
    11461 ttgactacat taccacgaga ttttgacatt ttttcgttgt tttcgcctaa gatcattcct
    11521 tgattgtata gtttttggaa tggttctttt gtaggaacaa caccgatatc gtataagaat
    11581 ttatgccaga atcgtgcata tagtaaatga agtaccgcat gttctgctcc accaatgtag
    11641 atgtcaactg gtagccaacg cttcaacttt tcataatctg ctagttcttt tttgttatga
    11701 gggtcgatat aacgcaggta ataccatgag cttcctgccc attgtggcat tgtattcgtt
    11761 tcgcgacggc cttttttacc tgttacagga tcaacgacat tgacccactc ctcgatattt
    11821 gctaatggag attctccagt accgcttggc ttgatgtttt ttgtcttagg caaccgtaat
    11881 ggtagctctt cttctgggac agctgtgact gttccgtcct cccaatggat gattgggatt
    11941 ggttcacccc agtaacgttg acgggagaat agccagtcac gtaagcgata gctgacttct
    12001 tttttcccta cgccattttc ttctagccat tcattcattt tatcgattgc ttcttgtttg
    12061 ttcatgccgt ctagaaattc agagttgatg tgcgtaccat cttctgtgta agcagctttt
    12121 tcaacatctc caccttcgat aactggaaga atttctagtc cgaaagtttg agcgaattca
    12181 aagtcacgtt catcatgtgc tggaacagcc atgatggctc ctgtgccgta tgaagataat
    12241 acataatcgg cgatccagat tgggatttcc ttgccattaa ctggattgat tgcataagca
    12301 ccagtaaata ctcctgtttt ttcttttgca agatccgttc tctttagatc tgatttttta
    12361 gctgtctctt cgatataagc ttctacagca gctttttgtt caggggtcgt aatttctcta
    12421 acaagatcta gttcaggtgc aagaaccgag taagttgcac cgaatagagt atctggtcgt
    12481 gtcgtaaata cggtatagga tttatccgta ccagccactt taaattcaat atttgctcct
    12541 actgaacgac cgatccaatt tctttgcatt tctttaatgc tttctggcca atcaactaat
    12601 tctagatcat ccaataagcg atcagcataa gcagtgattt tcagcatcca ttggcgcatt
    12661 ggttttctga ctacatcata gccaccacgt tcacttttcc catcgatcac ttcttcattt
    12721 gaaataactg ttcctaattc aggtacccag tttaccgcta cttctgcttc ataagctaga
    12781 cctttttcat aaagcttcgt aaagatccat tgtgtccatt tataatactc cggatcagtt
    12841 gtattcactt cgcgattcca gtcataacta aatcctaaag aattgatttg gcgtcggaat
    12901 gtttcgatat ttttttgggt aaactcagct ggatcgtttc ctgtatctag cgcatattgt
    12961 tcagcaggca gaccgaatgc atcccacccc attggatgca gcacgttgta tccttgactt
    13021 cttttcacac gtgaaaggat atccgttgcc gtataacctt caggatgccc tacatgtagc
    13081 ccttgaccgg atggataggg aaacatatcc agtgcgtaaa attttggctt ttcaggatca
    13141 tcatgggtgt tgaaagtatt cgtttttgcc cagtattttt gccatttttt ctcaatttct
    13201 ttatgattgt aactcatttg ctgtcctcct gttctattga aaacacttgt ttctattata
    13261 aatataacga aaaaaccggc agaatctgtt tatttttatt tccttttgct ttgttttctc
    13321 aaacttcaca aaagaaataa aaaaatccta taaaaagatt gctcttttta taggacgtaa
    13381 tctacgcggt accacctaat tttaccttag tgaaaaggcc tcgaacgttg taacggccgt
    13441 caccgccgct tgcttactcg ggtattcagc aagggcaact caaaggcgag ttcaaaagca
    13501 tccgtgcaca ttctcaccag ccatgcgctc tctgaaactt cagtcttttt actacttcct
    13561 tttcaagtgt tgtcatattt aagtagcctt atagtaacaa atatttttgt ggaattcaat
    13621 cgttatttct tcgaacagct attttattta gctacaatca acgtttgacc tggataaata
    13681 aagttgttct taatattgtt ccattcgatt agttgagcca ttgtaattcc atgactgtca
    13741 gcaacactcc aaacagattc tccagatttc acagtatagg ttttcgaacc agtaactgat
    13801 tgttggtttg ttgattgaga tgaacctttc ttcacaatca cttgctgtcc tggatagatg
    13861 aaattatttt tgatattatt ccattcgatt aactgatcca tcgtgatatg atgtttgttc
    13921 gctacgctcc aaactgactc gcccgctttc acggtataca tcgtattacc agtggatgat
    13981 gtacttgtcg tagcagacgt attcggtgta tttggtttcg ctgcagaagt agttgaacct
    14041 gtatttgtat ttgccgaagt tccaccttta acgatcaatt gctgtcctgg ataaatgaag
    14101 ttgtttttga tattattcca ttcgattaac tgatccatcg tgatgccgtt tttatttgcc
    14161 acgctccaaa cagattcacc tgctttcacg gtataagtgc cttgagacga actgctgcca
    14221 gtattaactg aactgctgtt atttgtattg gttgacgaac ctgtattacc tgacgtgctg
    14281 tttgttgatc cactgtttga aacagtcagt tgttgtcctg ggtagataaa gttattttgg
    14341 atattgttcc attggattag ctgagccatc gtaattccgt atttatttga gacgctccaa
    14401 acagagtctc cggctttaac tgtatatttc gttcctgaag ctgtattaga agaacttgag
    14461 ctggacgaac tagagccact tgtattccca gtatttgagc cagtatttgc tccagcatta
    14521 gaagaaccgc catttgatac gattagctgt tgtcctggat aaacgaaatt gttcttgata
    14581 ttgttccatt caatcaattg agccatcgta attccgtgat catttgagat cttccaaaca
    14641 gaatcaccag attgaacagt gtatttcgca ccagttgttt gtcctccgtt tgatgtacca
    14701 gcatttcctg aagagttggt attgttaccg gaattattcg tcgaagagcc attttcctgg
    14761 ctacctttga ttgtcagttt ttgtcctgga taaatgaaat tgttttggat gttgttccat
    14821 tggatcaatt gatccattgt gataccgaat ttatttgaga ttccccaaac agaatcacca
    14881 gattggacag tataagtggt cgaagttgct gaacctgagt ttgtattacc agaattgctt
    14941 gaaccgccag tactacctgc acttccagta ttattgccac ctgtagtcgc tccaccgcct
    15001 gcgtttccgc tagctggtgt atcatattgg gtcaatccgt aagttgcgat gatattattt
    15061 aatttgcctg cgtaaccagg atcagtcgca taacgccctg tcaaacaagc tgtcgcatct
    15121 gtataggatt tcgtgttgct cttccaagta ccggcatagt aataaccgtt gccaaatgaa
    15181 gtatttctaa gtacataggc attgtcattg aaagattcag caaaagaagg atattgtcgg
    15241 aaaggctcct ttttatttac ccattgatta tttaaaaatt caagcgtatc catgtagacg
    15301 gtttgtcctt gatagctgcc ttttatccca aaaagattat aataaggtgc ttgagataac
    15361 gcactactgc cccaaccgct ttctacaact gcttgtgcga tcatcactga tgcatataga
    15421 tcgttggctt gagcgattgg ttgagcataa gtagcaattt ctgtgataaa tgccgctgta
    15481 ttgattcttg cgccgaactg aacaggtgtt tcatccgctt gaacaggaac cggctgtact
    15541 aatggggcag cgacagaaca gcctaccatc gcagttccca cgattgctgc ccctcgtttt
    15601 gcttttcgaa aacgtttggt ctgttctaaa cgtctccgtt cttttcttgc aatgttttcc
    15661 atcttctatc ctccaacttc aatttatcta ttattaataa ttataacttc tcttaatatt
    15721 tattaaaagt tatttaagag ctttgttgtt ttttgtaatc atattgtaat ttaccgtaat
    15781 gaacaacttc tgttcatttt caagttcttc ctacgtctac gttcttgttt aaaaggattt
    15841 cgaaaaacac tgattttatt tccctaacat ttcatttgca ttaccaaaaa atgtctttcc
    15901 gattacagtt atttttttta taagaatatt ggttattcaa agaggaatca tacattggtt
    15961 ttatctcttt accgtttttt tcgctggacc aaaaatgcta taataagtca ttgcttcaaa
    16021 ggaggaattg tatgaaatat aaaacatcat ttcaggtggc tggtagcttc tttcttgtcc
    16081 tgtttttcat tttgggctgg atcgtaaagt tccatctgtc gtggctttct ggtttcgatc
    16141 agtggtttac aggcattgtc agagcttctt atcctgatct gaacagctac caactcttta
    16201 tgactaaatt cggtaatcct cttaccgtca tcattttatt tgcttgtgcg gctttatgga
    16261 tgtggtataa gaaaaaaagg gcagaaacat tttggttcgt ttctggattt attgtaattg
    16321 ctggaatcat caacccggtg atcaaactat ttttcatgcg agagcgtcct tcattggcgc
    16381 acttagtagt tgaaacaagt tacagtttcc ctagtggaca tgcagcaggc agtatgattc
    16441 tttacggttc tttactattt ctgcttccag cttttgttca aaaaagaacc ttacgcacat
    16501 tgcttcaatt gctgatgatg tttattatag taagtgtcgg gataagccgc atttatctgg
    16561 gcgttcattt tcctactgat atcatcggcg gctacttact cagtctttct tggctgtgcc
    16621 tgacttatcc agtgtataga gaaaaaagaa aacaaataga taactcttac agaaagaagg
    16681 acttttaatg acttttcctt attcagaagg aaataaaaga tatcattctt ggaattacgc
    16741 tttacgaaat gagtttggcg ggaaaatttt caaggtgccg atcgatggag gatttgactg
    16801 tccgaatcga gatgggactg ttgcccatgg cggttgtact ttttgcagtg tatctggttc
    16861 gggagacatg atcgttgcac ctgaagaccc tcttccaatc caattccaga aagaaatcga
    16921 catgatgcat caaaaatggc ctcatgtcca acaatacatc gtttatttcc aaaattttac
    16981 aaacacccat gcgccagttg aaataatcaa agaacgattt gagcaagtag tcaatttacc
    17041 aggtgtcgta ggattatcag tcggtacacg accggattgt ctgccagatg aagtagttga
    17101 ttaccttgct gaactgaacg agcggatgta tttatgggta gaacttggat tgcaaacaac
    17161 ttttgaagaa acttcaaaac tgatcaaccg agcacatgat tatcaaactt atttagatgg
    17221 cgtggctaaa ttacgcaaac ataatatccg tgtttgtacg catttgatca acggattacc
    17281 aggcgaaagt ttagaaatga tgaaagaaaa tgtcagacgc accattttag attcagatat
    17341 ccaaggaatc aagctccatt tgatgcatct gatgcgcaaa acgagaatgt tgcgggacta
    17401 tcatgaaggt cgccttcaat taatgagccg tcctgactat gtcaatgtca tttgcgacca
    17461 gctggaaatg ataccaaaag agatcatcat ccatcgtttg acaggggatg cgccgtggga
    17521 ttccttgatt ggaccaatgt ggagcttgaa aaaatgggaa gtcttgaatg caattgatga
    17581 agaacttctt cgcagagata gcttccaagg aaaatatgat gtacggaaaa aggtgagcgt
    17641 ctgatgttgc aaactgcttt gcatttcagc catacattac tgcaagaaat cttgcaacca
    17701 ggggatcacg tcgtagatgc aacgatgggc aatggccacg atacggtttt tctagcagaa
    17761 cacatcggaa aaactggtca tgtctatagt tttgatatcc agcaacaagc aatcgatgct
    17821 actcgtgaaa ggctagaaca gcgtcagtta gaagaacgtg tctcattgtt tctacaaggc
    17881 cacgaaacgt taggagaagt gatagctgaa caacaaaatc tcaaagcagg gattttcaat
    17941 ctagggtatc tcccaaaaag tgataaagca atcatcacta tgccagagac tacacgcaca
    18001 gctatggaag aaatattgaa acgacttgtg cctcgcggac gattgatcct tgtcgtctac
    18061 tatggtcatg aaggtggaga aaaagaactg gatatggttg attctttttg ttccaaactg
    18121 ccacaggaaa catataatgt gctgaattat cggtttatca accaaaagaa ccagccgcct
    18181 attttatatt gtattgagaa aaaaagataa ataaaaaacg caaaacataa atgatatgtt
    18241 ttgcgttttt ttctctaata ctcaggttag agcgttgatt tcataacctc tttattcacg
    18301 gtgctcaaaa gcttatatct gcggtaataa gtccaaccaa atcaaaaaca tgagaagctg
    18361 tttttgattg gctgttctta ttacttgatg caggacagct ttttcacaac ctctttattc
    18421 aaatacaaat tgaaattgaa cacatttttt tgacatataa cagatatata aaagaatggc
    18481 aaaaacattg atatataagc atttttaaaa gattttatat ttttgtatgt cattcatata
    18541 tcaatagcta acttaatatc agtcaaatta tgcccctttt ttgcccctca aatatcgctt
    18601 tacaacaaga acgtaagttc gtataatcgt tttgaggtga tttttatgat ggaagaattt
    18661 attagaaaaa atatcagtga tgaatatgca gacttttatg atcaaagcag taaaaaagat
    18721 aaattccaga tggatgtttc aatcttagct atattagctt tttccgaaaa taaacaacct
    18781 gtaactgcaa aaaaagaaac agtattctct gaaggcaaaa taaaaactcg atatatatta
    18841 gaggtagaaa ctaattttaa aaacagatcg gagtaatggt tatgcttttt aatgaga
//
LOCUS       DAIGQM010000058        17799 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.060, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000058 DAIGQM010000000
VERSION     DAIGQM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.060"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(6..1307)
                     /locus_tag="NOA48_002051"
     CDS             complement(6..1307)
                     /locus_tag="NOA48_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0790300.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(1537..3495)
                     /locus_tag="NOA48_002052"
     CDS             complement(1537..3495)
                     /locus_tag="NOA48_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCI0790301.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(3672..3938)
                     /locus_tag="NOA48_002053"
     CDS             complement(3672..3938)
                     /locus_tag="NOA48_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0790302.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(4448..6574)
                     /gene="pnp"
                     /locus_tag="NOA48_002054"
     CDS             complement(4448..6574)
                     /gene="pnp"
                     /locus_tag="NOA48_002054"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCI0790303.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(6762..7031)
                     /gene="rpsO"
                     /locus_tag="NOA48_002055"
     CDS             complement(6762..7031)
                     /gene="rpsO"
                     /locus_tag="NOA48_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCI0790304.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            7282..7845
                     /locus_tag="NOA48_002056"
     CDS             7282..7845
                     /locus_tag="NOA48_002056"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0790305.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(8098..8619)
                     /locus_tag="NOA48_002057"
     CDS             complement(8098..8619)
                     /locus_tag="NOA48_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCI0790306.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(8622..9464)
                     /locus_tag="NOA48_002058"
     CDS             complement(8622..9464)
                     /locus_tag="NOA48_002058"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCI0790307.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(9457..10182)
                     /locus_tag="NOA48_002059"
     CDS             complement(9457..10182)
                     /locus_tag="NOA48_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCI0790308.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            10358..10654
                     /locus_tag="NOA48_002060"
     CDS             10358..10654
                     /locus_tag="NOA48_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790309.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            11222..12814
                     /locus_tag="NOA48_002061"
     CDS             11222..12814
                     /locus_tag="NOA48_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0790310.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            12827..13567
                     /locus_tag="NOA48_002062"
     CDS             12827..13567
                     /locus_tag="NOA48_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0790311.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            13735..15084
                     /locus_tag="NOA48_002063"
     CDS             13735..15084
                     /locus_tag="NOA48_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0790312.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(15212..15802)
                     /locus_tag="NOA48_002064"
     CDS             complement(15212..15802)
                     /locus_tag="NOA48_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0790313.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            15949..17301
                     /gene="brnQ"
                     /locus_tag="NOA48_002065"
     CDS             15949..17301
                     /gene="brnQ"
                     /locus_tag="NOA48_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0790314.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         5117 a         3603 c         3406 g         5673 t
ORIGIN      
        1 ttcttttatt ctatttttct ttccgtggac tctactttga aataatcgat atgtgcatgc
       61 tggtattcta ataccgtgaa acggaatgat gcaatctcaa tgattgttcc tgcttttatt
      121 tctttatatc ggctagaagc aaagcccgca agtgtagtaa aattcgtttc ttcaaactct
      181 ggaatctcta catgaaaata acgctggaaa tcatctaatg ttagtttgcc ggagatgata
      241 taagagccat ctgactgttc cgctatcaat gcttcgtcca aatctgtctc atctcggatt
      301 tccccgacga tttcttctaa aatatcttca atcgtcacta agccgcttgt ccctccgtat
      361 tcatctttta agatagcaat atgctttccc ttttttcgca tgatcgtcaa taattttttt
      421 atagggatcg tttcagttgt tacgatcggc tcttcaatca actgttctac tgtcagctgg
      481 tcatctttat aagattgctt gatcaaatct ggcaaggtga cataacctaa aacattgtct
      541 tttgattcta agataaccgg atagcgagta tgtccttgtt caatcgaagc ttttatcgct
      601 tctttgacgg tttctgaagc ttcgaatact tgcatggacg tacggtctac ttgtatatct
      661 tttgccaagg tatcatcaaa ttcaaacacg ttttccaaat aatgatattc ttctttggtc
      721 aactctcctt tttcataaga attcaatgcg actaatgtca gctcttcttg agacaatgtc
      781 tcttctcctt cagatacgag acgcacacct aatagcttcc ctagccctgc agctgaatga
      841 ttcaataccc aaataaaagg aaacattact ttataaaaat aatgaagtgg tttaactacg
      901 aacaagacga ccttctccgt attgacgata ctatagctct taggaagcag ttcgccaata
      961 accacatcga tatacgtaac taaaataaat cccagcgcca cagagattgt actgctaata
     1021 gccgaactaa aaggtagttt accgatcact ggttctagta aagccgcgac agatccttca
     1081 ccgacccacc cgatgatcaa accggttagc gtaattccta attgactagc tgataaatag
     1141 ttatctaaat ggtgtgtaac atgaagagct agcttggcgt tctttacatt ttccttttct
     1201 agttgttcca atcttgatcg tctgattttc actaaagcaa attcacttgc tacaaaaaat
     1261 gaagtaattg caatcatcaa aaataaaata atgaaattga taaccatatt ctcccgcctt
     1321 tctctttttc tattgtaccc tttttctaca aaaagattga aaataatgcg tattcatatt
     1381 taggaataaa aaaggagatg cggcattttt cagccacatc tccttatcac ttcaaaatca
     1441 ttgcgttact tgttgctaaa cagctttttc atgacctctg ataaacggtg ttcaagtagc
     1501 tgacattcga cattagttca ggtcaaagcg ctactttcac aaccgctctt tcaaccatgt
     1561 tttccgagta tttccaatga taagcggaac agtttcatgt tttacttcgc tgtactctag
     1621 cccaaaccat gtttctggcg aggtagcgat ttttttgatt gccagttttg cctgcatgat
     1681 ttgacgttgc cattttccta gagttgtcac attggaaact acttcatcaa tcaggacaaa
     1741 ttggaaatcg ccaacttctc gccctggtgt cagagagtat ctttgtggct gttttggcaa
     1801 acggccttgt ttcatcaaat catggatgac ttggcgaaca tatacgttga tttcctgttg
     1861 gaccctgaaa cctaagaaca gattcacttg gacaataaaa tcagtgtcca tcatatctac
     1921 ttgatattct ttcgtatatg gctcatccgt cacttccaca tgaacaaacc aatagactcg
     1981 tgctctttta ggccgtttat ctaaaatcga atagatgaac tgtcggccaa ctttatcttc
     2041 agccatatca ggaaccaaga agaccacatt tgtctgatag attggtaaag aagtatcatc
     2101 acgtaattct ctaagctgcg ggatataatc tctcaaagac acatcctcgg ttgacgattc
     2161 gcgaataatg ttcccttgtt cccaaataaa catcacgact aagatgatca aaccaatcag
     2221 aacggctaca aaaccgcctc ggaagaattt gacaacactt gagataaaga aaacgacttc
     2281 tatcgcaccg aagaaaaagg taactaaata tgcaagccaa cgagaatgcc cattttggat
     2341 aagataaaag taaagcagtg ctgttgtcat caacatcgtc acagtgatcg atagaccgta
     2401 agcagcttcc atatgatgag acgttcggaa tgtgacaacc actagagaac aggcgatcca
     2461 taaaatcaga ttgactgctg ggatatacat ttgcccgata ctgttcccag gatacatgat
     2521 ctttaaccga ggcagcagtt tcaacttgat tgcttctgaa actagcgtaa acgaacctgt
     2581 aatcaatgct tgcgaagcaa tgactgcagc gactgttgca aaagcaacgc cgatcacgat
     2641 ccaactttga ggcatcattt ggaagaatgg attcaggttc ttgatttgct gtgcttcagg
     2701 gttttgataa acattcaaca accacgcagc ctgcccaaaa taattgataa ccaaacaaat
     2761 tttgacgtaa ggccagctca gacgaatatt tcgtttgccg acatgtccaa gatcggaata
     2821 aagcgcctct gcacctgtcg tagccaggaa aatatttcca agaatgaaca agcctaattt
     2881 gttatctgca ctaaaaagca gctggatagc ataataagga ttcagtgcac ggataactgt
     2941 ccagtcttga ctgaagttca ttaatcccat tacgcctaaa aaagtaaacc aagcgaacat
     3001 gattggtccg aatgcttttc cgacaatatc tgtaccaaag cgttggacca tgaataaaac
     3061 aaaaataata actaaagtga taatgacgat cacgttctgg ttattaccga accggtcaaa
     3121 aaactgcgga attcctcgca agccttcaat cgcagtcgtt accgtcacag caggggtcaa
     3181 taccccatct gctagtaagg cagctcctcc gatcattgca ggaatgatca aatatttccc
     3241 accttttcgg acaagtgtgt agagtgagaa aattccacct tcaccatggt tatctgcatt
     3301 caatgcaatc acgacatatt tgattgttgt cagtagagtc aatgtccaaa aaatcaatga
     3361 gactgatccg ataacaaaat caggattgat tcctgacaat ccgccattat cttcaacaat
     3421 cgatttcata acgtaaagcg gacttgtccc gatgtctccg tagacgactc ccatcgctac
     3481 aagcaggcca gccattgata tctttttggt attgtgcgtt gttgccacgt ttttccctca
     3541 tttcttgtta tatggatatc ctttaggtaa gcttgaatga tagatgatat tcttatccat
     3601 gacacccgct ttcctaaatt gcttctaatt atccaagtaa cacactgaag tgtcaactta
     3661 tttgaataaa attattcttt ctttggacgt tctctgatac gtcttgccac aaatgaataa
     3721 agagcaaggc aaaaaattgc acccaataat gctggtatca aataaaaacc gccgagttcc
     3781 ggtcccagtg gtcctagtaa aaattcgccg agccaactac ctaaaaaacc gataatgata
     3841 tttccagata cgcctcccgg gacttccttt cctaaaattg cgccagctat caaacctaat
     3901 ataccgccga taaataacga ccataaaaaa ttcagcatct cctttccctc ctttatccat
     3961 atttctcact tttattttac gctttattca gaaggactcc aaaaatatgc gccaagaaac
     4021 tccagaaaaa aagaagttgt aacaaaagtg ttcagcttat ttccgtagaa gctgcttctg
     4081 gaacaccgtg aatcagaggt tgtgaaatca gcggtttgac ctgagtatta gagaaacaaa
     4141 cggaaaaata gttcctcata ttttgccgtt ttttgagcta atatcgaggg acagctgatt
     4201 gaacatcgtt tattggagag gttgtaaaaa agctgttctg catcaagtaa taagaacagc
     4261 caagtaaaaa cagctcctaa tgtttttaac ttggctggac ttattaccgc agatgcaagc
     4321 ttttgaacac cgtttattcg aaaaaaaagg actgtgacac ggcttttgtc acagtcccct
     4381 tttttcgaat aattattgtc cccctgtcac cttcacgatc acaagtacat tattcctatg
     4441 aattaaatta tttttcttca tttttcgttg aaccatcttc gttcaacatt gcttttcttg
     4501 acagatttac gcgtccttgt ttatcgattt cagttacttt cacaaggatc tcatcaccta
     4561 gtttaacaac atcttcgact ttattgacac gatcgtttgc taattgggaa atatggacaa
     4621 gtccatcttt tcctttgatc aagttgacga atgcaccgaa tttttcgata cggacaactt
     4681 tccctagata aacttcacca actttgactt ctttggtcaa atcttcgatg atcttgatag
     4741 cttttttgat catttctgca tcagctgaag caatacttac ttttccatct tgatcgatat
     4801 cgattttcac accagtttca tcgatgattc cgttgatcgt atcgccgcct ttaccgataa
     4861 catctttgat tttagcaggt tcgatctgga tcatttcgat ttttggtgca tattggctta
     4921 attcttcacg tggagcagca atcgttgaag tcaattcttc taagatttcc atacgtgctt
     4981 gttttgcttg agttaatgct tcagttagga tttgttctgt gattccttga atcttgatat
     5041 ccatctgtaa agcagtgata ccatcttttg taccggcaac tttaaagtcc atatcgccaa
     5101 gatgatcttc cagcccttgg atatcagtta ggatcgtata gttttcacca tcagaaacaa
     5161 gtcccatcgc aataccggcg actggcgctt tgattggtac acctgcatcc atcaatgcta
     5221 atgtgccagc acagatactt gcttgggaag aagaaccatt tgattccaat acttctgcta
     5281 ctaaacggat cgtataagga aattcttctt ctgaagggat tacttgtgct aacgcacgtt
     5341 cacctaatgc gccatgtccg atttcccgac gccctggaga gcctgcacgt cctgtagaac
     5401 caacagaaaa ttgagggaaa ttgtagtggt ggatgaatcg tttgctgact tccaccccta
     5461 aaccatcaat gatttggtgc tctcctagag gtgcgagtgt acaagctgat aaagcttgtg
     5521 tttgtcctcg tgtgaacaaa cctgatccat gtacacgtgg caataagctg acctctgatg
     5581 acaatggacg gatttcatcc aatttacgcc cgtcaggacg gatcttatcg atggtgatca
     5641 attcacgtac gacatctttt tcaagatctt ctgtgatttg tttaacttct ttcaacaagt
     5701 gatcttcatc ttcatgacct gcaaatttct cagcataagc ttcgcggata tcgatcttca
     5761 cctgctcgat attatcttcg cgagcaagtt tttcttcagt cattactgct gctttcattg
     5821 tagcgtaaga agcatcaaag atttcttttt tcaatacttc atcaacttgc agtaaagtca
     5881 cttccatttt ttctttccct actgcttgaa cgatttcttc ttggaaagca actaactctt
     5941 tgatagcgtc aaaaccaaac agcaatgcac caagcatgtc ttcttctgaa acttctttcg
     6001 cgccgctttc aaccatattg atggcttgtt tcgttccggc aacagtcaat tcgatatctg
     6061 tttgttctgc ttgttctact gttggattca agacgtactc gccatttaca cgaccaactt
     6121 ctacgcctgc gattgggccg tcaaatggga tatctgagat tgatagtgct aaagaagaac
     6181 ctagcattgc tgccatagct ggcgagcagt ctgtttctac actcatcacg atgttcgtta
     6241 cttggacttc attacggaag ccttctgcaa acatcgggcg aattggacgg tcgatcaaac
     6301 gggcagtcaa tgttgcttcc gtacttggac ggccttctcg tttgatgaaa cctccaggga
     6361 ttttccctgc tgcatacatt ttttcttcat aattgatcgt taatgggaaa aagtctgtat
     6421 cttttgcttc tttagaggcc acagctgcac ttaagactac tgtatctcca taacggacta
     6481 aaacggctcc gtttgcttgt tttgctagct gaccgacttc gatttgtaag ggacggccgc
     6541 cccatgtcgt tttgaatact tgtttttctg acataacttc tccttttcct tctcgtgaaa
     6601 gcaagacgct actaaacaaa tgaaaactgc cgaaagccgt cttttgagca gctttcattt
     6661 ggttagtagg agtccatcta gcttgatcac ggaattttac ttaattgata tacgagtaaa
     6721 aaaagtgaga ttcatgtgaa tcccactctt tttgactaaa attaacgacg caagcctaaa
     6781 cgtttgatca attcgcggta acgttgaacg tcagttttac gtaagtaagc taacaagtta
     6841 cggcggtgac caactttttt cattaggccg cggtatgaat gatggtcttt tttgtgcacg
     6901 cgtgcatgtt cattcaagtg gttgatttct tcagttaata cagcgatttg tacttctgga
     6961 gaaccagtat ccccttcatg gcgagcgtat tcgttgatga tttcattctt gcgttctttt
     7021 gaaattgcca tttctttcac ctctttcgat tattcccctg cgactgagta aaacgttggt
     7081 gattcgctta accaagtggc aggtcatgtg cctagagcac acagctatac tttacctgaa
     7141 accgggttga aaatcaagta gttaatcatt aagaaaaggt agttttcaaa caatcttact
     7201 actacttttc catttttgtg gtaaactata atgcgaaaat agacttgaaa cacagtcttt
     7261 taagaaaggg gtacatattc catgattaca atggatgata tcattcgtga aggaaatccg
     7321 accttacgcg aagttgcaaa agaagtttct cttccattaa gcgaagaaga tatctcttta
     7381 ggaaaagaga tgcttgagtt cttaaaaaac agccaagatc caatcaaagc tgaagaacta
     7441 cacttacgag gcggtgttgg cttagctgct cctcaattag atatttctaa aagaatcatt
     7501 gctgttcacg taccaagtcc tgacccagag gcagatggac cttctctaag tactgttatg
     7561 tataatccta aaattttgag ccattctgtt caagatgctt gtttagggga aggtgaaggc
     7621 tgtttatctg ttgatcgaga agtaccagga tatgttgttc gccatgccaa aatcactgtg
     7681 tcttattatg atatgaatgg tgaaaaacac aagattcgtt tgaagaatta tgaatcgatc
     7741 gtcgttcaac atgaaatcga ccatatcaac ggtgtgatgt tctatgacca catcaacgat
     7801 caaaatccat ttgcactaaa agaaggcgta ttggtgatcg agtagagaat tggcaggttc
     7861 cttcgatact atgctacaag aaagctttat aaaaaagggg agtgctcaaa agctgcactt
     7921 ccctttttta tgtttctcca ctaatcgaaa tttagataga catctagaaa tcgcaattcc
     7981 aaaaaattct gtgtattgga tacgcatctt ttcttatttt ttcttatttc ttccatatgg
     8041 gtgtttatct cagagatgat agaatagttt ctaggataaa aagtagcagc tacgatgtta
     8101 tccttcgtag aggattcctg cttcagctag tttttgtttg atgtttttca gcatatgctt
     8161 ttctgggtag cggatcgtat gcagatggat gccgcctgtt aattcggata acaaagtagc
     8221 attacttttt tgataacgtc tcataaagga atcgatatct tgtggcgttt tgatgtgcaa
     8281 agttcctgct aactcaccgt aaaggggatg ttccacaatt acatcaatga tttcaccacc
     8341 attttcaacg attagtctca gttcttcttc tgtttgatct tttccatgct ggacagcgat
     8401 tttactgatg tgcccagtat tggtttcttc tgtttcgagg atataacctc ttgctgttgc
     8461 cacgatactt ttacctgcag ctcgtagtaa agcaatatcg cctacaatga tctgacggct
     8521 gactccaaaa gttttcgcaa acttgctagc actcactggt ttttctgtat ttgccaaggt
     8581 ttgcatgatt tgttttcgcc gtgtctctcc ttcgatcaca cttattcctc cttcattttg
     8641 ttttggtatt cgcgcgagtg tttcatcaaa tcaacatacg tgtctgttat tgtttcctta
     8701 tatcccttat ttttcagcag actaacaact ttatccaata cttgctgctc tctttttgca
     8761 tcataaactg cttggttttc ttcttttttc acttgtccta ttttagttac cgtatccatt
     8821 cttttttcta ataaagcaac caactctcga tcgatcatat cgatcttatg acgtaatgtt
     8881 tcaagagact cttctgttag ttcttcctct actgtcttga tgatacgagc aggatttcct
     8941 gcaatcacta cattgtcggg aaaagatttg gtcacaaccg aacctgcgcc gactactacg
     9001 ttgtccccta gagtgacacc cggcgtgacg ataactcctc cgcctaacca aacattatta
     9061 ccgattttaa tgggttttgc gtactccaga ccgctgttac gtttcactgg atgtagtgga
     9121 tgcgtcgccg tgtaaagctg gacattcgga gcgaacatgc agttatcacc gatttcaatc
     9181 gtgctgacat ctaaaaatgt acaattgaaa tttgcataaa aattctcccc aacaaatata
     9241 ttatatccgt aatcaaaatt gataactggc tccatataga tttttttccc tgtacggcca
     9301 aaagtctctt tcaacaattg ggatcgcagt tccgctgatt ctgcttggtt gatgatttgg
     9361 ctttgacttc ttgcaaacat acggtcggca accagctcag gatcattggc aaaataaagc
     9421 tcgcctgcaa tcattttttc tttttcggtt ttgaattcag tcataatctg ctcctaattc
     9481 ttgtattttt ttgaaaacaa ccgctccgtc ttcttgaata aacgtataag gctccgctaa
     9541 ataaacaggc gtttgattga ttactaagat tttggctgac ggctggcgaa actgtaccag
     9601 atcacaaaac ggatgaactt gaaaactcgt tccaacaatg acgatcagct ctgcttggct
     9661 gacggcataa gccgcctgct ccatgactcc atcttgaaac ccttcaccat ataacacgat
     9721 gtctgggcgt atttgtcctc cgcatgcttg atgtttgtcg ctgtgaagat attctttcca
     9781 gtctaccgtt tgttgacatt ttcgacaatg acattgatac agactcccat gaaaattgac
     9841 gagttgcggg cttttagcct ttgcgtgcaa accgtcgatg ttttgggaaa caacccaaac
     9901 atttttttct ttcgctagat gtgctatttc caaatgaatg atattgggtt ttgcttcagg
     9961 atgataaatc tttttgacaa attgatagaa tttatccggt tcattcacca ttgcttgatg
    10021 actcagcaag tattccggct gctccatccc gtggtagatt cctgacaaag atcgatagtc
    10081 tggcactcca gaaggtgtgg atacccctgc accggtcaaa aatgtaattt gctgataagc
    10141 taatatctct tttgctgctt cgtctactgt taattgtttc atgttttgtc acctcacttt
    10201 ccattatagc ccatactcga acaaatttat tgttgaaaag tcagaaaaat gggaataaaa
    10261 aagtgttatg ggcatttgag caatttatca caatgttcac tgacaaaaga atgaaaacgt
    10321 gttacaatac tgctgtataa aagtgaggtg aatcgatatg ttaccattct ttatttattg
    10381 gggcgttatt ctggcttgta tcgcctggtt agcgttaagc gtttatttct ctgtttttta
    10441 tcttgtacgc aaagaaaatg gaaatctttg ggcttttgct ttattcaacg tgattgccgc
    10501 aattgtttta gccattacat tagccgtata tcgaacatgg ggctggggaa tcacccaata
    10561 ctcaagtttg atttatctaa tattagccat ttatggcgtc gttgttcttt tgcaagcgat
    10621 cctaggacgt gagccaaaga aagcggcagc ttaaatgatc gagatggaac tggacacagg
    10681 aaattttctg ttctagttct ttttttattg tattacatac atttttgtgt ataattatac
    10741 tatcgtttgc aatggataga tgattcacat tttgattgtt ttttcggtaa aagtaaagat
    10801 ttctatattt atcagtattt tttcaaaaac cagcagttat agattgacaa agcctctcga
    10861 gtatcgtaaa ctttttttgt ataaataact gaatacgaga tgcctcaatc aatgaggtag
    10921 aggtcgcgag aatcattaac cctgtggagt gaagcaaaca tggagaagca ggaataggga
    10981 ggatcgccga aatgtgcact tttttgcttg gagtgtatgt tgggacgcaa gttaagagct
    11041 tgcggactgt cttagcagtg atgctaagtt gcgctatgtt ttgtgagagg tttatcacct
    11101 tatggaattt tagcggcctt tttatatcta taaatcggtc gctttttatt ttttcagata
    11161 aagctttacc gcatttcatc tagaccgctc gtgtatcata taatcagaaa gggagaaaaa
    11221 aatgaaaaaa aatatggttt cagttgccgt actatttgct tttgtcttct cactattcag
    11281 tgtgggatct ctggcaaatg cagatgaaaa aacaccgagc gatgagtttc gcgtaggtat
    11341 ggaggctggg tatgcaccct tcaactggtc tcaacaaaca gatgagaata atgccttgcc
    11401 aattcaaggc caaaatagtt acgccggcgg ttatgatgtt caaatcgcta aaaaagtagc
    11461 agatggttta gggaaaaaat tagtcatcgt ccaaacgaaa tgggatggtc tggctcctgc
    11521 ccttcaatca ggcaagatcg acgcgatcat cgccggaatg agccctactg ctgaacgacg
    11581 aaaagaaatt gattttaccg atccttatta cgaatcacaa ttagtagtag tagttcaaaa
    11641 agatagcaaa tatgcaaaag caaaaagttt agcagatctt tctggagcaa agatcactgc
    11701 tcagttaaat acattccact atactgtgat cgatcagata ccagatgtgc agaaacaaca
    11761 agcaatggat aatttctcag caatgagaac agctttagct tctggaatga tcgatggtta
    11821 tgtcagcgaa cgtccggaag gtgtaacggc aactagtgtg aacaaagact tggaaatgct
    11881 tgaattcagc ggtgcagatg gcttccagac aaacccggaa gatgttcaga tttctgttgg
    11941 tatgcgtaaa ggcgacccgg atatccaaaa agtaaaccag attctttctg gcatctctaa
    12001 cgatgaacga accaaaatta tggaccaagc agtcaaagat cagcctgctg caactgatag
    12061 tgaagaaaaa cctggcatca tttctgattt cactacgatt tggaaacaat acggcaatat
    12121 gttcttacga ggtgctggac ttaccttgtt catcgcattg atcgggacag ttgtcggtac
    12181 tacacttgga ttactgattg gtgtcttccg ttcggtacct gaatcaggaa atgcactgac
    12241 tcgcttcttc caaaaaatcg gaaatgcact tctttctatc tatgtcgaag tattccgcgg
    12301 aacaccgatg atggtacaag caatggtcat cttctacggt ctggcactcg cttttggcat
    12361 ttcattgaac cgaacgattg ccgctttgtt tattgtctct ctcaatactg gagcttacat
    12421 gacagagatc gttcgtgggg ggatttttgc agtagatgaa gggcagttcg aagctgcgca
    12481 agccattggt atgacccatg gccaaacgat gagaaaagtt gttattccac aagttttacg
    12541 gaatatcttg ccagcaacag gaaatgagtt tgttatcaat atcaaagata cagcagtttt
    12601 aagtgtaatc ggcgtagctg atttgttctt ccaaggaaac tctgcttccg gtgcgaattt
    12661 ccaattcttc caaacattta cgatcgtcgg gatcatctac ttagtcatga cctttacgat
    12721 caccagaatc ctgcgggcgg tagaaaagaa aatcgatggt ccttcagctt ataccaagct
    12781 tgaagaaatc gacaattcaa atttgcagga ataaggagga agaatcatga atgaaaaaat
    12841 tattgaaatc aaacatctaa gaaaaagctt cggtgaaaat gaagtattga aagatatcag
    12901 cgtaacagtc aataaaggtg aagttgtgac gatcatcggt tcttccggtt ctggtaaatc
    12961 tactttcttg cgctgtatca atttactgga aaaaccaaca ggcggcgaga tcatttataa
    13021 tggagaaaat gtattagctc ctaaatataa tttacctaaa tatcgaacga atctaggtat
    13081 ggttttccaa tccttcaacc tgttcaacaa tatgaatgtc ttggaaaact gtatgtctgg
    13141 tcaaacaact gtcctgaaac gagataaaga aactgccaaa aaagtagcaa tcgaaaatct
    13201 ggaaaaagtt ggtatggatc gttatatcga agccaaacca gcacaattat ctggtggaca
    13261 gaaacagcgt gtcgcaattg ctcgggcatt atcaatgaat ccagatgtat tgctattcga
    13321 cgaacctact tcggcgttag accctgaaat ggttggcgaa gtgcttaata cgatcaaaga
    13381 cttagcacat actggcttga caatgcttat cgtgacgcat gagatggaat ttgcaaaaga
    13441 tgtatctgac cgtgtcattt ttatggataa aggtgtgatt gcagaagaag gtacaccaga
    13501 agatatcttt gtccatccga aagaagaacg tacaaaagaa ttcctttcac gtattttaaa
    13561 tgcttaggat caatagctga ttgggacaaa gagctgcggt gtttaccgca gttctttttt
    13621 atgaattact cataaaaggt aaatttctga aaattttgga atcttagttg tgtttttcag
    13681 aaaactctct taatatggaa gtaattaaac ttttttagtt aggatgattt aaaaatgaat
    13741 gaagagcaag aactgcagcg tggactgaaa aatagacatg tccaactgat ttctattggc
    13801 ggagcgattg gaacggggtt gtttttaggt tccggaaagt ctatccagct agctggccct
    13861 tcgatattgc tcgcctatct tattactgga tgcatctgtt ttttcattat gcgtgcgtta
    13921 ggcgaacttc tgttatcaaa caccaataac cattcttttc tggattttgt tgcagaatat
    13981 cttggcaaaa aagcggcttt catcactggc tggacgtatt ggttctgctg ggtatcgatt
    14041 gcaatggccg atttaacagc catcggaatg tatgtacgct actgggcgcc tggtgttcct
    14101 cagtggcttc ctgaactgat tgcattaggt cttcttcttt gcttgaatat ggtggctgtc
    14161 tcattgtttg gtgagttaga gttttggttt gcattgatca aagttgtagc gatcattgcc
    14221 tttatcctcg taggagctta tatgatcctc acccactata cgacagatat tggcacagcc
    14281 agtatcacga atctatggtc tcatggcgga ttctttccaa ctggtgcaaa aggatttatc
    14341 ttagctttcc aaatggtaac ctttgctttt gctgggatag aattagttgg attagtcgct
    14401 ggagaaacag aaaatcctga aaaagtgttg ccggaagcta tcaataatat tcctatcagg
    14461 atcatcttat tttacttagg atctcttttt gtcattatgg caatctatcc atggaacagc
    14521 ttgaatccag ataacagtcc atttgtagaa gtattttcgg aaattgggat cacgattgct
    14581 gcttccttga tcaatttagt cgtattaagt gcagcagctt ctgcctgcaa cagtgcaata
    14641 tatagtacag gacgtatgct tcgttcttta gcgcaagaag gcagtgcccc taaaaaattc
    14701 aaaaagttaa caacacatca tgtgccaggg aatgctttga cattttctac tatcgtcatt
    14761 ttcatttctg ttatcttgaa ttacgtgatg cctagtgaag tattcacact agtaagcagt
    14821 attgccacta cttgtttctt gtttatctgg agtatgcttg tctacacgca catgaaatat
    14881 cgtaaaagta tcctcggcaa aaaagctcat tcatttaaaa tgccgttgta cccatttagt
    14941 aattatctgg tatttcttta catggccttt gtgtgtgtcg tcttgttcct aggaaaagat
    15001 acgagaatcg ctttattact aacacctgtg tggttcttgc ttctattact aatctatcat
    15061 atgaaatatg aacgtaagaa gtaagaaagt agttgtgaca gaagtggtca gcttcgagaa
    15121 ataagaagga atttacgaaa attgcttctt aaatttttgt gaaatttcgg cttatttctt
    15181 ggagataaaa gcttctgtcc cagcctcttt tctatttccc cggaaacaac cgctgataat
    15241 aggcatctgc ttttttatag gaaaaaatcc aaataccaga tacaaaaaaa cgtccgaata
    15301 acccgatcaa cggtacaaaa aagacaccgg caatcaagca taagttaatc atcatggaga
    15361 taagacttcg acggtccttt gacaaaactc tcacgacatg ggaatctggt ttatttgctt
    15421 tcatgatttg cctcatcaag ataccaaaag aaaaactcca catcgtgtat actaagacat
    15481 aagccatctc aggccaaaaa gcttcagggt tacgcccgac ccaactagta acagaaggac
    15541 ataaagtcag ccaaaagagc aaaaagatat tcgaccagac cactcggtaa ttaattcgtt
    15601 ctgccatctg aaatatacga tgatggttca cccagatcac cgcaacaaat ataaagctga
    15661 tggtataagc taataatgta tttcggatga cccataaaga atgaaagcta gatgtattag
    15721 ggatcttgat ctctaataca ataactctca aaacaatggc taccactcca tcagtaaatg
    15781 cttctaatct cgactttgtc acgatgattc ctcctcagat gattcagcgc ttttatttta
    15841 tcacttacgt tattaaataa ccatcgtttt atatagggaa ttttctgaaa attgttgcat
    15901 atttttcgaa attttgttac ttttaaaaaa accgtaaagg agttatgtat gacaaaaaaa
    15961 ttatcattta aagactatct ttttataggc tccatgcttt tcggtctatt ttttggtgct
    16021 ggaaatctta tctttcccgt tcatttgggt caagaagcag gcgctgctac cttttgggcg
    16081 aatctaggtt tcttggttac cggtatcggt cttcccttct taggggtgat tgccattggt
    16141 gtatcgaaaa gctcaggtgt atatgaatta gcaaaacgga taaatcaaac atatgcgatg
    16201 gtttttacca tcttgcttta cttagttatc ggaccgtttt ttgctttacc tcgccttgca
    16261 accacatctt tcgagattgg tttagcacca tttatcgatc ctagcagaca gacgctatat
    16321 ctagcaattt tcagtattgt attttttgtg ctggcttggt ggttttcaag aaaaccgaca
    16381 aagatattag attatgttgg aaagttcctg aatcctgcat ttttggtttt attaggtgct
    16441 ttgcttctcc ttgctttttt gaatccacta ggttctgtaa atcaagcgcc tattcagcca
    16501 aattatcaag agcatgcttt tttcacaggg tttactcaag gatataacac attagatgcg
    16561 cttgctgctt tagcatttgg gatcatcatt gtcacaacaa tccaaaacat gggtgtaaca
    16621 aaacctgctg aaatcgctaa agacacgatc aaatctggtg cgatcagcat tatattgatg
    16681 ggaatcattt atactttgct cgcttattta ggtgctatga gcttaggtag ctttgctcta
    16741 agtgaaaatg gcgggatcac gctggctcag attgctgatc attatttagg tacttatggc
    16801 agtatcttat tagcatttat cgttatatta gcttgcttga agaccggtat tggtttgatt
    16861 acagcttttg cagaaacatt cacagatttg tttccgcaaa gaaattacgc attctttgtt
    16921 gcacttgcta gtatccttcc ttgtttagcg gcaaacgtag gcttgacgaa tatcattcaa
    16981 ttttcgttgc ctgttttgat gttcatctat ccattagcaa tgacactgat tttactagtg
    17041 ttagttggtc ctttgtttaa gcagcgtacg gctgtttatc gaatgactac ttattttaca
    17101 ttgattgctt cgatttttga tgggttgaac gcttgcccag aaactatcaa acaaacacct
    17161 attgttcaaa atcttttata tgttgcggaa agctacttgc cgtttttcaa attggggatg
    17221 gggtggatcg taccagcagt tatcggtttt gttatcggac tgatttggag tttcgctaag
    17281 aaagaagaag tagcagattg ataaaagagg ttgtgaaaga gacgttcagc cttgagcaat
    17341 aaaaagtaat tttgaaaaat ggcttctcac atttttgcat aaatttgact taataccgag
    17401 aaactgactt ttgaacaccg tttattgaga ggtcgtgaaa aagccgctta gtttcaagta
    17461 ttaagaaata ttttgtgaaa atggcttctc acatttttgc ataaatttga cttaataccg
    17521 agaaactggc ttttgaacac cgtttattga gcgtctataa actgacctga gtattagaga
    17581 aacaaaacgg caaagtagct ccatatactt tgccgttttg ttttgaacta ataccgaaga
    17641 gaagctgatc aaacaacatt tcttttataa tatagatttt agacatatat atgatataaa
    17701 aatagttttc gcaaaaaaac ttgggagcgt caataatttt gtgtaaataa attgtcctcc
    17761 tgcaaaataa ttagttactc agtaaacatt gaaactaat
//
LOCUS       DAIGQM010000059        17291 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.061, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000059 DAIGQM010000000
VERSION     DAIGQM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.061"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            94..2370
                     /locus_tag="NOA48_002066"
     CDS             94..2370
                     /locus_tag="NOA48_002066"
                     /inference="COORDINATES: protein motif:HMM:NF024867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0790315.1"
                     /translation="MSLKLKGIKIDSFRAFERQKYFDCVNPVFNEISNLIVLYAPNGT
                     GKTSFFDAIEWSLTGEISRLNENKNVRDIASQERKYILKNKYSSAEVDSVELAFDDGS
                     FYALTTKRLNGKQTTDYVEGNETKKTVDLTAKELKILRQKNLLTHNQIDAFLRSQSAE
                     GRYDALSNFWDKENVSEDYKNLVLFVNEMNKVLGQQETKMNQLTKEIEKLESNAKIWQ
                     TINQLKENYAKLNGKNSKKDPLLKNQLGLQELYIESNKLKSNNQIKLNQFEEERQQLE
                     NLITMIQEYRQIPQQIEWSEKQVADVNEKLAHLTEIETIEEKKKALFDEKIDLSNHLK
                     RCNFLINHEADFQALEMAEQNSNREINEWINQRKKCEQALITLQKEHQEQEVTLSECQ
                     NKRALRTNQLTEIKELNSYSDVKAKRQLLDHEIKQQKKKKIGLEAKLGKIKLTLTKLF
                     SLLNLDDHQLSQKDYSKDPDYSFLLEQISQLDDIWQERKKLEVDLTQKKKERSSLEDL
                     GSQLEQLKKLGYSIVTDTSSSVCPLCLHDHQEFQHIIQKIEASTADLLPIEQLTKEIS
                     HLEGMIDESTRRLTEVVSGVKQQIQIQITVKETEINQLDQDLLQVTLKLKQQEEAYLT
                     NEKHWYKLNEYSQKYGIDCEKIAEETQKRVKSLQEELVKLTNEYQNIKEKINQNEQLN
                     VKNTHTLKTIELHYQQAKKSLNDLKGNEQYQHYQQEQAFYEALGISVISDFKRQCKRE
                     LEKINEQETKLIAEKNND"
     gene            2517..3206
                     /locus_tag="NOA48_002067"
     CDS             2517..3206
                     /locus_tag="NOA48_002067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0790316.1"
                     /translation="MEKNKQKLTTAIYKLNEKNQLLGQLSGLTSDFISETGIETKRSE
                     QAKVKKIYDHLSRKVQELKELKDSKLTEIKKQIKSTFNLYTVNQIFQMIEPHPDFRKI
                     SFKINEANPDKLGLDIMCKRTEDEEDAPILYLSSAQVNILSLSIFLGTALENTDKVNT
                     IFMDDPIQHLDSLNELSFIDLLRILAFKLGTQIIFSTHNRQFFDLCQRKLDANYHNAS
                     FIEMNYTENQL"
     gene            3552..3740
                     /locus_tag="NOA48_002068"
                     /pseudo
     CDS             3552..3740
                     /locus_tag="NOA48_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3995..4726
                     /locus_tag="NOA48_002069"
     CDS             3995..4726
                     /locus_tag="NOA48_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0790317.1"
                     /translation="MGNSFKNKALYHQLVDLLKNQMESNMIPHDKLPSERELTAQYGV
                     SRTTVRLALKELENTGYIYRRHGKGTFVSDIKKNVADLAGTYSFTEQMKSLGRTAETR
                     ILAFEKIEADKFIAKQLNLSLGEVVFKLSRLRIADREPLMIEDTYLPVKFFLSLNDQL
                     LRSKPLYDLFSEDFNQTVRLADEELYASVASKEDAKQLIISEGAPVLHLARQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            4739..5911
                     /locus_tag="NOA48_002070"
     CDS             4739..5911
                     /locus_tag="NOA48_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0790318.1"
                     /translation="MFTVGKEKLDQLGAEITTREIRQQPELWEETLDHYQTVQKELDN
                     FLAIVKEKANGQRTRVIFTGAGTSQYVGDTLVPYLRKNGDRQAFSFESIGTTDIVAEP
                     EEYLIKEDPTLLVSFARSGNSPESLAAVEIANQMVDTIYHLSITCAVEGKLAQISQSD
                     SNSFLFLMPARSNDSGFAMTGSFSCMTLGALLTFDQTVLVKKQQYLKVLNNLGNEVIT
                     RVNEIEKIVQLDFERIVYVGSGSLAGLTREAQLKILELTAGKIATIFDSSMGFRHGPK
                     SFINQKTIMFGFVNNNPYTRDYDLDVLEEVRGDEIASGVFAITQPGQRNFTGDKFEFT
                     TEAELLPDGYLALSYIMVAQIVALLSSIKVNNKPDTPSPTGTVNRVVKGVTIHKYK"
     gene            5934..6941
                     /gene="lacD"
                     /locus_tag="NOA48_002071"
     CDS             5934..6941
                     /gene="lacD"
                     /locus_tag="NOA48_002071"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0790319.1"
                     /translation="MITLTRGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEL
                     NDEQIERFKELVSSELTPYASSILLDPEYGLPAASARHEDAGLLLAYEKTGYDVTTPG
                     RLPDLLADWSVLRLKEQGADSIKFLLYYDVDEDPEINHQKHVFVERLGSECAEEDLPF
                     YLELLSYDTQISDVHSLEYAKVKPHKVNSMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     STDEVAYTEEEAAKYFLEQSQATDLPFIFLSAGVSTKLFQQTLFFAKDSGSTFNGVLC
                     GRATWKNGVKPFIKSGEESARAWLKSEGRENIESLNNVLAQTASSWYDKVQVEKEAAV
                     N"
     gene            6953..7891
                     /locus_tag="NOA48_002072"
     CDS             6953..7891
                     /locus_tag="NOA48_002072"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HCI0790320.1"
                     /translation="MIVTVTMNPSIDISYPLASLNVDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGYHGAFIADELKHAGIKQKFTDIKEESRDSIAVLHEGNQTEI
                     LEAGPTVSYEEQQNFLENFKELIKKAKIVTISGSLAKGLPSNFYQTLVQLTEEQSAKV
                     LVDTSGESLHQVLAGKQKPFLIKPNLEELSTLLRHSFSIDRLEEVQEELIQPIFAGIE
                     WIIVSLGKAGALAKHKDCFYRVTLPTIKAVNPVGSGDATVAGFAYGLSQEMDEIELLK
                     FCMATGMANAQEGQTGHVSPVNIQSHIEKITVKKIE"
     gene            complement(7912..8574)
                     /locus_tag="NOA48_002073"
                     /pseudo
     CDS             complement(7912..8574)
                     /locus_tag="NOA48_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370247.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            8725..10503
                     /locus_tag="NOA48_002074"
     CDS             8725..10503
                     /locus_tag="NOA48_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HCI0790321.1"
                     /translation="MNTFEIKEDFLLNGKPFKILSGAIHYFRVDSADWYHSLYNLKAL
                     GFNTVETYVPWNLHEPKKGDFHFEGILDLEHFLSIAEELGLYAIVRPSPYICAEWEFG
                     GFPAWLLNEGTRIRTNETVYLNHVADYYDVLIKKIVPHQLTNGGNILMIQIENEYGSY
                     GEEKDYLRSIRDLMLDRGITVPFFTSDGPWRATLRAGSMIDEDILVTGNFGSKAEENF
                     SSMEAFFNEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAKELAEAIKEVVLRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLDEQGNPTEKYYAIQTMIHETFPDIQ
                     QMEPLTKDTMEMKDIPLIDKVSLFSTLDTISQSVKMKYPETMEMLGQNTGYILYRTSI
                     KKDAEHERLRVIDGRDRSQLFLNQKLQATQYQTEIGEDIIVPMPQEDNQLDILIENMG
                     RVNYGHKLLADTQKKGIRTGVMADLHFITDWNQYCLPLESCEKVDFSKEWHPNQPSFY
                     RYEVTLDEVEDSFIDLSKFGKGVVFVNQTNIGRFWEVGPTLSLYIPKSLFKKGNNEIV
                     IFETEGTFQPEIQLVKAPLYKEMKEG"
     gene            10507..10986
                     /locus_tag="NOA48_002075"
     CDS             10507..10986
                     /locus_tag="NOA48_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCI0790322.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAKNDIEK
                     SGLKLATPPGVKLSVLPIEKAANNILAGKYDSQRLLIIAREPDRLLKLVELGVPIEEI
                     NVGNMSQTNETRSITKSINVVDQDVEVFNKLQAKGVRLVAQMVPSDKAENFMALLAK"
     gene            10999..11895
                     /locus_tag="NOA48_002076"
     CDS             10999..11895
                     /locus_tag="NOA48_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790323.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAVIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGALSWSLSRMIPVFLAL
                     AFGGGLVEQVVVVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGAVKNFEGIFNSLPMLAIALVGFSLAAISYKNGQLIPH
                     SPAPKDVTSNDSDEGEIEDDEI"
     gene            11882..12691
                     /locus_tag="NOA48_002077"
     CDS             11882..12691
                     /locus_tag="NOA48_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0790324.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKLYGDNSPELKEMMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIDGKDTVSGLKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKLSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            12729..13133
                     /locus_tag="NOA48_002078"
     CDS             12729..13133
                     /locus_tag="NOA48_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0790325.1"
                     /translation="MGKQLVLISHGLFCEELKKSTEMIMGPQESIHTVSLLPSESAED
                     FREKFETVIANLDDFVVLADLMGGTPCNVVSKIILEGQVIDLYAGMNMPMVIDFINSQ
                     LIGTELSLIESATSNICYVNGRIFSDDDDEDE"
     gene            complement(13606..14487)
                     /locus_tag="NOA48_002079"
     CDS             complement(13606..14487)
                     /locus_tag="NOA48_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790326.1"
                     /translation="MTFAIYAYLKEKNNLFLWISLYLAFFIFDNTIIYMTEFLNSFAQ
                     SYDQVFMSAPAVKTIIFMGNAFFSISILAELQKEKLSPLHYALLLALAVWMITIPLMD
                     NSAFKVWLYYLGNQLFLFYLGIYCWRGTKKDVPLLNKHYLKQLMFINLFFSILIIIED
                     SFVIFNVDQYSSLVTKIYNRSVSEDIFSIVICVLLLHFFIKKYQPQKEKTQKQDTSLL
                     IQDFCQDHQFTQRETEIFILLLSHRTNQEIADQLFLSLGTVKTHVHNIFIKLDIKKRT
                     QIIPLFEKYKEAIESTV"
     gene            14813..15832
                     /gene="ptcA"
                     /locus_tag="NOA48_002080"
     CDS             14813..15832
                     /gene="ptcA"
                     /locus_tag="NOA48_002080"
                     /EC_number="2.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine carbamoyltransferase"
                     /protein_id="HCI0790327.1"
                     /translation="MGKKDFITTENYTKEEIQQIVDLSLKIKAAIKNGFYPPLLKNKV
                     LGMIFQQSSTRTRVSFETAMTQLGGHAEYLAPGQIQLGGHETIEDTSRVLSRLVDILM
                     ARVERHHSVYDLATNATIPVINGMSDFNHPTQEIGDLCTMIEHLPAGKKIEDCKVSFI
                     GDATQVCFSLGLIATKMGMEFVQFGPEGFQLNEDHRARLDAICKDSGGSYTISDQIDV
                     IEGSDFVYTDVWYGLYEAELSEEERMRIFYPKYQVNTDLIKRAGKQAKFMHCLPATRG
                     EEVTDEVMDGPNSICFDEAENRLTSIRGLLVYLMRDYAEKNPIDETKKAAAKKDLEAL
                     LGETF"
     gene            16069..17106
                     /locus_tag="NOA48_002081"
                     /pseudo
     CDS             16069..17106
                     /locus_tag="NOA48_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355588.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
BASE COUNT         5915 a         2744 c         3508 g         5124 t
ORIGIN      
        1 aattaaaaac gatggctaaa aaagagaaaa aagcacgaat acaagagtat ataaaacatg
       61 agctgtcaaa tcttaacgta aaggaaggaa ccgatgagtc ttaaattgaa agggataaaa
      121 attgattcgt ttcgagcatt tgaaaggcaa aaatattttg attgtgtgaa tcctgttttt
      181 aatgaaatat caaatttgat tgttttgtat gcgccaaatg gaaccggaaa aacctctttt
      241 tttgatgcca tcgaatggag cttgactggc gaaatcagtc gactgaatga aaataaaaat
      301 gtccgtgata tcgcctccca agagcgaaag tatattttaa agaacaaata ttcctcagcc
      361 gaagtggaca gtgtggaact agcatttgat gatggcagtt tttatgcatt aacgacgaaa
      421 aggttaaatg gaaagcaaac gacggattac gttgaaggga atgagaccaa aaaaacggtt
      481 gatttaacag cgaaagaatt aaagatttta cgacaaaaaa atttattgac acacaatcaa
      541 atcgatgctt ttttacgatc gcagagtgcc gaaggaagat atgatgcttt aagtaatttt
      601 tgggataaag aaaatgtatc tgaggattat aaaaatctag tcttattcgt caatgaaatg
      661 aataaagtat taggacaaca agaaactaaa atgaatcagc taacaaaaga gattgaaaaa
      721 ctcgaaagta atgcaaaaat atggcaaaca atcaaccagc tgaaagaaaa ttatgccaag
      781 ttaaacggaa agaatagtaa aaaagatcca ttgttaaaga atcaattagg tttacaagaa
      841 ttgtatatcg aatcgaacaa attaaaaagc aataatcaaa taaaattgaa ccagtttgaa
      901 gaggagcgac aacagctaga aaatttaatc acaatgatcc aagagtatcg acaaataccg
      961 cagcagatcg aatggtctga aaagcaggtt gctgatgtca acgaaaagtt agcccatttg
     1021 acagaaattg agacaatcga agaaaaaaag aaagcactgt ttgacgaaaa aatagacttg
     1081 agcaaccatc tcaagcgttg taactttctt atcaatcatg aagcagattt tcaggcacta
     1141 gaaatggctg aacaaaacag taatagagaa atcaatgaat ggattaatca acgaaaaaaa
     1201 tgtgaacaag cattgattac tttacaaaag gagcatcaag agcaagaagt aacattaagt
     1261 gagtgtcaaa ataaacgagc gttgcggacg aatcaattaa cagaaatcaa agaattaaac
     1321 agttattccg atgttaaagc gaaaagacaa ttacttgatc atgaaatcaa acaacagaaa
     1381 aagaaaaaaa tagggttgga agccaagtta ggtaagataa agctaacgtt gacaaaattg
     1441 ttttcattac taaacttaga cgatcatcag ttaagccaaa aagactattc aaaagatcct
     1501 gattattcat ttttgttgga acagataagc caacttgatg acatttggca agaaagaaaa
     1561 aaattggaag ttgatttaac acaaaagaag aaggaacgtt cctctttaga agatctgggc
     1621 agtcagttag aacagttgaa aaaattaggt tattctatcg taacggatac gtcttcgtct
     1681 gtctgtccat tatgtctcca tgatcatcaa gaatttcaac atatcatcca aaaaattgaa
     1741 gctagtacgg cagatctttt accgattgag caactgacga aggaaatcag ccacttagaa
     1801 ggaatgatcg atgaatcaac taggcggtta actgaggtag tctctggagt aaaacaacag
     1861 attcagatac aaataacggt taaggaaact gaaatcaacc aacttgacca agatctgtta
     1921 caagtaacct taaaattaaa acaacaagaa gaagcgtatt taaccaatga gaaacactgg
     1981 tacaagttaa atgaatacag ccaaaaatat gggattgact gtgaaaaaat tgctgaagaa
     2041 acccagaaaa gagtaaagtc actacaggag gaattggtaa aattaacgaa tgagtaccaa
     2101 aatatcaaag aaaaaatcaa tcaaaatgaa cagctgaatg tcaagaatac tcatacgctc
     2161 aaaacgatcg aattacatta tcaacaagcg aaaaaaagct taaatgattt aaaaggaaac
     2221 gaacagtatc aacattatca gcaagaacag gcgttttatg aagcgcttgg tatttctgtt
     2281 atctctgatt ttaaaaggca atgtaaacgc gagttagaaa aaatcaatga acaagaaacc
     2341 aagcttattg ccgaaaaaaa caacgactag aacaagtaaa tgggaaaagt aaaacagaat
     2401 tagtagaaga acaacgaatc caagcagagc agattcggca gctcgttgta cggaggaaat
     2461 atatcgaaaa gatatcttat caactgtttg accaagtaat cattgcacca gaagaattgg
     2521 aaaaaaataa gcaaaaattg actacagcta tttacaaatt aaatgaaaaa aatcaactgt
     2581 tgggtcaact atctgggctt accagtgatt ttatctctga aacaggtatc gaaacgaaaa
     2641 gaagcgaaca agcaaaagta aaaaaaatct atgaccactt aagtagaaaa gtacaagaac
     2701 taaaagaatt aaaagacagt aaattaaccg agatcaaaaa gcaaatcaaa agtacattta
     2761 acttatatac cgtcaatcag atttttcaaa tgatcgaacc tcaccctgat tttcgtaaga
     2821 ttagttttaa aatcaatgaa gcaaatcccg ataaattagg actggatatt atgtgcaaac
     2881 gaacagagga tgaagaggat gccccgattt tatatctaag ttctgcccaa gtaaatatat
     2941 tgtctttaag tatttttcta ggaaccgctc tagagaatac agacaaagtg aatacgattt
     3001 tcatggatga tccaatccaa cacttagata gtcttaatga attatccttt attgatctat
     3061 taagaatcct tgcatttaag ctaggaacac agatcatctt ttccacccat aaccgccagt
     3121 tttttgactt atgtcagaga aaattagatg ccaattacca taatgccagt tttatcgaaa
     3181 tgaattatac agagaatcag ttgtaacaaa tttagttagt cagaaaaagt gaataaggga
     3241 gctctttgat gagagctgag gttagctgaa agattcagag tataaaacaa aaattgccta
     3301 cagaagtaaa taaagagacg aatagagaat caatcccaac gaataaggga ttgattcttt
     3361 ttttctagat taaatacaga taggaagaat atatagattg gatggagagt tgtactacct
     3421 atacgaaagc agaagctttt ttaggctcta cactttttga tattggcgaa attcgccaac
     3481 atttttttat gatttaaacg gtatagaaaa gacatcattc actatttggg ggctatttaa
     3541 ccagagaaac cgaaacctat acgacaactt tgcgaacatt tagaaagttt ctgacacaga
     3601 tccgaaatgc cctccgctac aattactcaa acggattact agaatgttta aacaagccta
     3661 tcaaagtatt taaacgaaat ttttatcatt tcaaacggcg aatcatgatt cgtcacgata
     3721 aaactttttt aagcaaataa acatactaag attagtaggt ttctatttcc tgtttttttc
     3781 aactggtatc agatttcagc acttatgact gttattttcg ctaggaacaa tttcttaaaa
     3841 atggatagtt ttattatttc aataaaataa tcattgctaa atcaacgatt taagacggtt
     3901 gtagaatttt tttcagattg tttgttgaca aaaataaaaa aaccatctta ccattagttt
     3961 gtggttataa ccagtttaaa agaaggagaa acctatggga aattctttta aaaacaaagc
     4021 tttgtatcat cagttggtag atttacttaa aaatcagatg gaaagtaaca tgatacccca
     4081 tgataaatta ccctctgaac gagaattaac tgctcaatac ggagttagtc gtacaacggt
     4141 tcgattagct ttgaaagagt tggaaaatac aggttatatt tatcggagac atggaaaagg
     4201 aacatttgta tccgatatca aaaagaacgt agcagattta gcaggaacct atagctttac
     4261 tgaacaaatg aaaagtttag gtagaactgc tgagacgcgg atcttagctt ttgaaaaaat
     4321 tgaagcggac aaatttattg caaaacaatt gaatctttca ttaggagaag tagtcttcaa
     4381 attaagtcga ttgcggatag ctgatcggga accgcttatg atcgaagata cctatttgcc
     4441 agtcaaattt ttcttatcat taaatgatca gcttttaaga agcaaacctc tatatgatct
     4501 tttttccgag gattttaatc agaccgttcg attggcagat gaagagctat atgcaagtgt
     4561 tgcctcaaag gaagatgcga aacagctgat aatctcagaa ggagcacctg tccttcattt
     4621 agcacgtcaa acctataata tgaaaaatga aattatcgaa tttactttaa gtgtcgcccg
     4681 tgcggatcaa tttcattatc agatccgcca tattcgaaat agttaggaga atcgaaacat
     4741 gtttacagta ggaaaagaaa aactggatca gctgggtgct gagatcacga ctcgcgaaat
     4801 acgccaacag cctgaacttt gggaagaaac ccttgatcac tatcaaacag ttcaaaagga
     4861 attagataat tttcttgcaa tagttaaaga aaaggcaaat ggtcagcgaa cacgtgtaat
     4921 cttcactggt gcaggaacat ctcaatatgt aggagacaca ttagttcctt atttgcgcaa
     4981 gaacggtgat cgccaagcat ttagctttga aagtattgga acgactgata ttgtcgcaga
     5041 acctgaagaa tatttaatta aagaagaccc aactttactt gtatcatttg cgaggagtgg
     5101 aaacagtcct gaaagcttgg cagcagttga aattgcaaat cagatggttg atacgatcta
     5161 tcatttatca attacgtgtg ctgtagaagg aaaactagct caaattagtc aatccgattc
     5221 caatagtttt ttattcttga tgccagcacg ttccaatgat agtggctttg ctatgactgg
     5281 tagcttttcc tgcatgactt taggagcttt gttgacattc gatcaaacag tattagtgaa
     5341 gaaacaacaa tacctgaagg ttttaaataa tttaggaaat gaagtaatta cccgagtaaa
     5401 tgaaattgaa aaaatcgttc agcttgattt tgaacgcatt gtttatgttg gttcaggaag
     5461 tctagctgga ttaacaaggg aagcgcaatt gaagattctg gaattgacag ccggaaaaat
     5521 tgctaccatc tttgattcat caatgggctt tcgccatggt ccaaagtcgt ttattaatca
     5581 aaaaacaatc atgttcggtt ttgttaataa taatccttac acgcgtgatt acgacttgga
     5641 tgtcttagaa gaagtgcgtg gagatgaaat cgcttccgga gtgttcgcca ttactcaacc
     5701 agggcaacgg aatttcactg gcgataaatt cgagtttaca actgaggccg aattactgcc
     5761 agatggctat ttagcactaa gctatatcat ggttgcccaa atagtcgctt tgttatcatc
     5821 gattaaagtg aataataaac cagatacacc gtcaccaaca ggaacagtta accgagttgt
     5881 aaaaggtgta acgattcaca aatataagta aaaataaact gggaggaaga accatgatta
     5941 cattaaccag aggaaaaaaa gcagcaatgg atcgtttatc gacaaaagat ggtattatca
     6001 gtgccttagc gattgatcaa cgcggagcat taaaaaaaat gatcaaagcc ttaaatgtag
     6061 aattaaatga tgaacagatt gagcgtttca aggagttagt ttctagtgaa ttaacccctt
     6121 atgcatcttc tattttattg gacccagaat atggtcttcc tgctgcaagt gcacgacatg
     6181 aagatgctgg tttgttgttg gcctatgaaa aaaccggcta tgatgtaaca acaccgggac
     6241 gcttgcctga tttattagca gattggtcag ttttacgatt aaaagagcaa ggagccgatt
     6301 cgattaagtt tctactttat tatgacgtag atgaagatcc ggaaatcaat catcagaagc
     6361 atgtcttcgt agaacgttta ggtagcgagt gtgccgaaga agatttgcca ttctatttag
     6421 aattgctatc atatgatacc caaatttcag atgttcattc acttgaatat gccaaagtaa
     6481 aaccgcataa agtcaatagc atgatgaagg aattttcgaa accacagtac aaagtagatg
     6541 ttttaaaggt agaagttcct gtcaatatga attttgtaga gggtttcagt acagatgaag
     6601 tagcgtatac cgaagaggag gcggcaaagt acttcttgga acaaagtcaa gcgacagatt
     6661 tgccttttat tttcttgagt gccggtgttt ctacgaagct attccaacaa acattgtttt
     6721 ttgctaaaga ttcaggttcg acctttaatg gtgtgctttg tggtagagct acttggaaaa
     6781 atggtgtgaa gccgtttatc aaatctggtg aagaatctgc tcgtgcctgg ctgaaaagtg
     6841 aaggtcgtga aaatatcgaa agcttgaaca acgttttggc acaaacagcc agttcttggt
     6901 atgacaaagt ccaagttgaa aaagaagcag ctgtgaacta ggaggagagc tcgtgatagt
     6961 aactgtaacg atgaacccgt caattgatat ttcctatccg cttgcttcct tgaatgtgga
     7021 tactgtcaat cgaacagatc aagttagtaa aacagcaggt ggaaaaggac ttaatgtaac
     7081 ccgagtaatc catgatctaa agggggatgt actcgctaca ggagttctcg gtgggtatca
     7141 tggggcgttt attgcagatg aattaaagca tgccggtatt aagcagaaat ttacagatat
     7201 caaagaagaa agccgggatt caatcgctgt tttgcatgaa ggaaatcaaa ctgagatttt
     7261 ggaagcggga ccaacagttt cctatgaaga acagcagaat ttcctagaaa acttcaagga
     7321 gctaataaaa aaagcaaaga ttgtcacaat ctcaggtagt cttgcaaaag gattgccatc
     7381 aaatttttac caaacgttgg tccaattgac agaagagcag tccgcaaagg ttcttgtcga
     7441 cacctctggg gaaagcttgc atcaggtttt agctggcaaa cagaagccat ttttaatcaa
     7501 accaaatctt gaggaattat cgacactact gagacattca ttttcgattg atcgattaga
     7561 agaagtccag gaagaattga ttcaacctat cttcgcaggt attgaatgga tcattgtttc
     7621 tctaggaaaa gctggagctc tcgcaaaaca taaagattgt ttttatcgag ttacgctccc
     7681 tacgataaaa gcagtcaacc cagttggttc aggagatgct acagtcgctg gatttgccta
     7741 cggcctatca caagaaatgg atgaaataga acttttgaag ttttgtatgg ctactggtat
     7801 ggctaatgca caagaaggac aaacaggtca tgtttcaccg gtgaatattc aatcgcatat
     7861 tgaaaaaata actgtaaaaa agattgagtg aaaaaatcga tctagataaa atcaatgatt
     7921 ttttgagacc aactcaattt ggtagaagtt ccatttttgt aggattcaac gtactccagt
     7981 agttgttgtg aatctctacg tttcgtcact cggacttgca gaacggtcgt ttcatcggta
     8041 agaatcttta atgatttcgc aacatttaaa ggagttggaa atataatttt atttgtttcc
     8101 gtaaaatctt cctcattcat gtggatattg tagtcttgtt taaagcgctg acagctggaa
     8161 ttgtaataac acaattcttg acaattagga tccacatatt gttcgggcaa ataagtttgc
     8221 tgatagatat atgcagtttt ttagtttttc gtaaatgtct gatgtaatca taaaatgcta
     8281 aggctggcag tttaagcttg tttaaatagt gtggatcatt ccctcgaacg attgataaaa
     8341 cttggacttg atcattactg atagtgaata attcaatgtc agaaaactag aacagttttt
     8401 ctttacgtga aacaaatgag tcacgacctt gatgacgaat tatgaatcca tcctttattc
     8461 attcagggag cgaatgactg taatagagct tacgttaaat atttgtatta attctgcttc
     8521 tgtataaagt ttattgccat tttgggatgt ctaaattaac ccttcaaaca acatcaaaga
     8581 attaaacttt tcgttagagt ctttggtttt gtatgtataa tttgatttta acacgttctg
     8641 ttatgttgga tatggttgaa tttctatttc aaattattta atatatcaat atattgaaaa
     8701 cgcttttatt taaggaggga gcttttgaac acatttgaga ttaaagaaga ttttcttcta
     8761 aacggtaagc cctttaagat actctcagga gctatccact attttagagt ggattcagcc
     8821 gattggtatc actcgttata taatctgaaa gcattgggat ttaatacagt tgaaacttat
     8881 gtaccatgga acctacatga acctaaaaaa ggagatttcc attttgaggg aattttggac
     8941 ttagaacatt ttttgtccat tgctgaggaa ttaggactat acgcgattgt tagaccatct
     9001 ccatatattt gtgcagaatg ggagtttggt ggttttcctg cttggttact taatgaggga
     9061 actcggatcc gaacaaatga aaccgtttat ttgaaccatg tggcagatta ttatgatgtt
     9121 ttaataaaaa aaatcgtgcc gcatcagctg acaaatggtg gaaatatttt aatgattcaa
     9181 attgagaatg aatacggttc ttatggagaa gaaaaagact atttacgttc gatacgtgat
     9241 ttaatgttgg acagaggaat aacagtgcca tttttcactt cggatggacc atggcgtgcg
     9301 acactcagag caggcagcat gattgatgaa gatattttag ttactggaaa ttttggttca
     9361 aaggctgaag aaaatttttc ttcaatggaa gctttcttca atgagcatgg gaaaaaatgg
     9421 cctttaatgt gtatggaatt ttgggatggt tggtttaatc gttggaagga accgattgta
     9481 caacgtgatg caaaagaatt agctgaggca atcaaagagg tcgtgctgag aggaagtatt
     9541 aacctgtata tgttccatgg aggaacaaat tttggattta tgaatggttg ctcagctaga
     9601 ggagtgattg atttgccaca gattacttct tatgattacg gagcaccctt agacgagcaa
     9661 ggaaatccaa ccgaaaaata ttatgcaatc cagacaatga ttcatgaaac gttccctgat
     9721 atccaacaaa tggaaccttt gacaaaagac acaatggaaa tgaaagatat tccattaatt
     9781 gataaagtca gtttattttc aacattagat acaattagtc aatcagtaaa aatgaaatat
     9841 ccagaaacga tggaaatgtt aggacaaaat acaggttata ttctgtatcg cacctcaata
     9901 aaaaaagatg cagaacatga aagactgaga gtaatcgatg gaagagaccg tagccaacta
     9961 tttttaaatc aaaaactgca agctacacaa tatcagacag aaattggtga agatatcatt
    10021 gttccaatgc ctcaggaaga caatcaatta gatattctaa ttgaaaacat ggggcgcgtt
    10081 aattatggtc ataaattatt agccgataca caaaaaaagg gaattcgtac aggggtcatg
    10141 gctgatctac attttatcac tgattggaat cagtattgtt taccactaga gtcatgtgag
    10201 aaagttgatt tttcaaagga atggcatcct aaccagccaa gtttttatcg ctatgaagta
    10261 acacttgatg aagtggagga tagcttcatt gatctatcaa aatttgggaa aggtgtcgta
    10321 tttgttaatc agaccaatat tggacgtttt tgggaagttg ggccaacact ttcgctatat
    10381 attccgaaaa gcttatttaa aaaaggaaac aatgaaatag tgatttttga aacagaagga
    10441 actttccaac cagagatcca attagtaaaa gcaccactat ataaagaaat gaaagaagga
    10501 taaacaatga gtattatcgg agtaagaatt gatggacgtt taattcatgg acaagtagcc
    10561 aacttatgga caaccaagtt gaacatcaca cggattatgg ttgtagatga tgaagttgca
    10621 aaaaatgata ttgaaaaaag tggattaaag ctggcaactc caccaggagt taaattaagt
    10681 gtattgccga ttgaaaaagc tgctaataat attttagcag gaaaatatga ttctcaacga
    10741 ttattgatta ttgctcggga gccggatcgt ttattgaagt tggtagaatt aggagtccca
    10801 attgaagaaa ttaatgttgg gaatatgtca cagacaaatg aaacacggtc cattactaaa
    10861 tcaatcaatg tggttgatca agatgtagaa gtatttaaca aattacaggc taaaggtgtt
    10921 cgcttagtag cgcagatggt tccaagtgat aaagcagaaa attttatggc tttattagcg
    10981 aaataggagg ataaataaat ggatatctta tggtggcaga tcttattatt aacattatac
    11041 gcagggtatc aaattttaga tgagttacaa atttattcat cgttgagtgc acccgttttt
    11101 gccggattat ttgctggtct agtgatggga gatctaaaag caggacttat tattggtggt
    11161 agtatgcaat tgactgtact tggtgttggt acctttgggg gggcatcaaa aattgatgcc
    11221 aactctggaa cgattttagc gacagctttc tcagtagcgc taggaatgaa cccagagcaa
    11281 gcaattgccg taattgcggt accagtagct agcttgatga ttcaattaga tatattagcc
    11341 cgttttgcga atacgtattt tgcgcatcgc attgataaat tagttgaaga tatgaactat
    11401 aaagggatcg aacgtaattt cttaatggga gccctctctt ggtcactttc tcgtatgatt
    11461 cccgtttttc tagcattagc atttggagga ggactagtag aacaagtggt agtcgtgcta
    11521 aatggtgatt tgaagtggtt aggcgatgga ttatcagtag ctggagcagt tttaccagct
    11581 gtcggttttg ctattctact acgttacttg ccagttaaaa agcatttccc ttacctaatt
    11641 ttaggattta cattaacggc attactagga accgtcttta ctaacatgca ggttttagga
    11701 acgggtgttg caggagctgt gaagaatttc gaaggaatat ttaattcact tccaatgtta
    11761 gcaattgcac tagttggatt ttctttagca gccatcagtt acaaaaatgg acagctgata
    11821 ccacattcgc cagcccctaa agatgttaca tcgaatgatt cagatgaagg agagattgaa
    11881 gatgacgaaa tctaattata agttaacgaa ggaagacttt aagcagatca atcgcagaag
    11941 cttgtttact ttccaattag gctggaacta tgaacggatg caaggatcag gctatcttta
    12001 tacaattctg ccgcaattac gcaagcttta tggtgataat tctcctgaat taaaagaaat
    12061 gatgaaaact catacacaat tctttaatac atcaaacttc ttcaatacta tcgttaccgg
    12121 gattgacttg gctattgagg aaaaggaagg tattgatggt aaagacactg tctcaggttt
    12181 aaaagctggg ttgatggggc cttttgcagc aattggtgat tcgattttcg cagcgttaat
    12241 tccaacaatt tttggagcct tagcagccaa tatggcaatt aatggcaacc caactggaat
    12301 ttttatttgg attatcgcac aaatcgctgt tatgattttc cgttggaaac aattagaatt
    12361 tgcttatcgt gaaggaatct ctttagttac cacgatgcaa catcgcttaa ctgccttgac
    12421 agatgctgca actttgttag gggtcttcat ggttggagcg ttggtcgcta ccatgattaa
    12481 tgtaaaattg tcttgggcac cgagtattgg tgatgtgacg ttaaacatgc aaaataacct
    12541 ggatatgatt ttaccacgat tattaccagc cggtatcgtt gcagcaattt attggatgct
    12601 tggcaaaaag aatatgactt ctactaaggc aattttcata gtattagtgg tttgtgtagc
    12661 attatcagct ttaggcgtga tttcaaaata agtcaggctg attccaatta gtgatgagga
    12721 gtggttcaat gggaaaacaa ttagttttaa ttagtcatgg acttttctgt gaagaattga
    12781 aaaaaagtac agaaatgata atggggcctc aggaaagtat tcacacagta agccttcttc
    12841 cttctgaatc agcggaagat tttcgtgaaa agtttgaaac agtaattgcc aatttagatg
    12901 atttcgtagt attagcagat ttaatgggtg gcactccgtg taatgtagtt tcaaaaataa
    12961 ttctcgaggg tcaagtaatt gacttatacg caggcatgaa catgccaatg gtgattgact
    13021 tcattaacag tcaattaatt ggaacagaac tttcattaat cgaatctgct acaagtaaca
    13081 tttgttatgt gaatggacgg attttcagtg atgacgatga tgaagatgag taagataaaa
    13141 tatatgagtg atgaagccaa agaaatattt ctctgatcat actatagata aaagacattt
    13201 caaacttgta atttgagttt ggaatgtctt tttatctagt tttgttcaaa attttggaca
    13261 aaaaagagac cctttgtcaa atgatgttgg taaagagaaa ttctagaatg attggtgaaa
    13321 gattgagaaa aaaatgttca gcatcaagga ataagaagga atttccgaaa tttgacaaga
    13381 aacataaata cttttttttg gtgttgatta ttatctactt ggtgtgtctc aaatttttta
    13441 taaatttcag cgaatttttg aagatgccgc ttttgtctca ttctccattt ttttatttta
    13501 tgattaacct cataaaaaag tgggacatta attagatttt ttctgattaa tatcccagac
    13561 tcgtctacag actgagaact tggaagggat acttccagga cttttttaaa cggttgactc
    13621 aatggcttct ttatactttt caaaaagggg gataatttgc gtgcgctttt ttatgtcaag
    13681 tttaataaaa atattgtgga catgagtttt aaccgttcct aatgaaagaa agagctggtc
    13741 agcaatttcc tgattggttc gatgtgacag tagcaatata aaaatttccg tttctcgttg
    13801 agtaaactgg tgatcctgac aaaagtcttg aatcaagaga gaggtgtctt gcttttgtgt
    13861 tttttctttc tgaggttgat attttttgat aaagaagtgc agtaataaaa cacatataac
    13921 aatcgaaaaa atatcctctg agacactacg attataaatt tttgtcacta aggagctata
    13981 ttgatcgaca ttgaaaatca cgaaactatc ttcaataatg atcaaaatac taaagaagag
    14041 attgatgaac atcaattgct ttaaatagtg tttgttcagc aaaggtacat ccttttttgt
    14101 tcctcgccaa caataaattc ctaggtaaaa caggaagagt tgattgccca gataatagag
    14161 ccagacttta aaggctgaat tatccatcag tgggatggta atcatccaaa cagccaaagc
    14221 aagcagtaaa gcataatgga gaggggaaag tttttctttt tgtagttcgg caagaataga
    14281 aatggaaaaa aaggcgtttc ccataaaaat aatcgtttta actgctggcg cactcataaa
    14341 tacttgatca taactttgtg caaaggaatt gaggaactcc gtcatataaa taatcgtgtt
    14401 atcaaaaatg aagaatgcca aatacaaact gatccagaga aataagttgt ttttttcttt
    14461 taaataagca taaatagcaa aagtcatcgt gattgaatat agaatgatca atagaatgtt
    14521 gtaaacaaaa atagctatcg tattgaatcc cctttcattt ttttccttac ctcaaatttc
    14581 ttattttaat tataacaccg atttttttat ctttactttt aattcctata aacttccttc
    14641 taaacttttg taaacccttg gaaaataaat ggtttatatc caaaaataaa ccagcctgta
    14701 gcacgtatag atcggcaatg ataacgttta caactaataa cttatcgtaa actctcactt
    14761 tttttcctaa agtgaagatg caaagcaaac aaattactta ggaggttcca ttatgggaaa
    14821 aaaagatttt attacaactg aaaattacac gaaggaagag attcaacaaa ttgttgacct
    14881 gtcattgaaa atcaaagcgg ccatcaagaa tggtttttat cctcctttgc taaagaacaa
    14941 agtgttaggg atgattttcc aacagtcttc taccagaacg cgggtttcgt ttgaaacagc
    15001 aatgacacaa ttagggggac acgcagaata tctagcacca gggcaaattc aattgggtgg
    15061 tcatgaaacg atagaagaca cgagccgagt tctttctcgt ttagttgata ttttgatggc
    15121 tcgtgtggaa cgtcatcata gtgtgtatga cttagcaacg aatgccacga tcccagttat
    15181 taacggtatg tctgacttca accacccaac gcaagaaatt ggcgatcttt gcaccatgat
    15241 cgaacatctt ccagcaggca aaaaaattga agactgcaag gtttccttta ttggagatgc
    15301 cacacaagtc tgtttctctt taggattgat tgcaacaaaa atgggaatgg aattcgttca
    15361 atttggacca gaagggttcc agttaaacga agaccatcgc gcacgactag acgcaatttg
    15421 caaagattct ggtggctcct atacgatatc cgatcaaatc gatgttatcg aaggttcgga
    15481 ttttgtttat acagatgttt ggtatggact gtatgaagct gaactatcag aagaggaacg
    15541 catgcgtatt ttttatccta aataccaagt gaatacggac ttgataaaac gtgctgggaa
    15601 acaagcgaaa tttatgcact gcttgcctgc cactcgtggg gaagaagtca cagatgaagt
    15661 catggatgga ccgaactcga tctgttttga tgaagcagaa aatcggttga cttcgattcg
    15721 cggtctctta gtgtacttga tgcgagatta tgcggaaaaa aatccaatcg atgagaccaa
    15781 aaaagcagcg gctaaaaaag acttggaagc tttgctaggt gaaacatttt agacgcaaga
    15841 gatgaggaaa ggaaataatc tgcgtatcat gacgatgcgt gaggattgtc tctgttctag
    15901 aggaggggct aacgatctga aaatcgattc tttctagcag aatcttgatc tcacactaat
    15961 gtagctttta tgccgcacta gaaatcatac gaggtgagtc cgcaggttac aagaatcgtt
    16021 caatcgctgg tccaacctta ttcccttgta ccggaaagga agaaaacaat gggagaaaag
    16081 aaaaaattta gtttgatgag tgctatatta tctgttattt gtgttgtatt tgtggcagaa
    16141 gcggctgcac cggtagcagc aatcggaaat tcacaatttt tttggtggat ctttttattg
    16201 attgcattcc ttttgcccta tggattgatc tcgtcagagt taggaacaac ttatatcggt
    16261 gatggcggta tctatgattg ggtgacacaa gccttcggac atcgctgggg atctcgcgtt
    16321 tcttggtatt actggattaa ttatccactg tggttagctt ctctagcagt agtctgccct
    16381 gatttattga tgacgatcac aggcagcgaa ttttcaacag ctgctgctat catgatcgaa
    16441 ctgatcttta tatggatcat tgtttggatc agtttttatc cggtcagtga cagtgtgtgg
    16501 attttgaatg gagcagctgt tatcaaaatg ctgctggcaa tcttgattgg tggcttaggt
    16561 ctctatactg cgtttactaa gggtgtggcg aatgagttta ctctttcttc catgctgcca
    16621 agtttcaatt taaatagttt gtcctttatt tcagtaatca tttttaactt attaggattc
    16681 gaagtgattt gtacattcgc gaatgatatg gaaaatccta aaaagcaaat ccctcaatcg
    16741 atcattgccg gtggactggt gattgcagct atttacattt tttctgcatt cgggatcggt
    16801 gtagcaattc ctacggatca gattagtaca ggcagtggat tgatggatag ttttaagtta
    16861 ttgacaggat caacaggcgg ctggttcatt atttcgatgg cctttttatt cttactgaca
    16921 ttgtttggca atatgatttc ttggtcgtta ggggttaaca atactgcttg ttatgcagcc
    16981 gaaaatgacg atatgccgaa agtatttgcc aaacgcagca aaaaaaacgg catgcctact
    17041 ggtgcggcga ttatgaatgg tattgttgct tctatcattg gtgcgatcat cgttgttgct
    17101 gtagtatcat ttttcttggg acgttcaaga ggttaatcgt caaatatatc agcaatttta
    17161 cctattatct taaggagcag cttttcgctg cttctttttt tgtatagata aactgcttct
    17221 atcactgatc atcgatgttg tctaactgat gtcgccgaat gcaagcatta cctttgccag
    17281 attaaaaaat a
//
LOCUS       DAIGQM010000060        17231 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.062, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000060 DAIGQM010000000
VERSION     DAIGQM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.062"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            6..320
                     /locus_tag="NOA48_002082"
     CDS             6..320
                     /locus_tag="NOA48_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790328.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            875..948
                     /locus_tag="NOA48_002083"
     tRNA            875..948
                     /locus_tag="NOA48_002083"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:909..911,aa:Ile,seq:cat)
     gene            complement(1464..1766)
                     /locus_tag="NOA48_002084"
     CDS             complement(1464..1766)
                     /locus_tag="NOA48_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790329.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(1986..2352)
                     /gene="ssrA"
                     /locus_tag="NOA48_002085"
     tmRNA           complement(1986..2352)
                     /gene="ssrA"
                     /locus_tag="NOA48_002085"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2523..3296)
                     /locus_tag="NOA48_002086"
     CDS             complement(2523..3296)
                     /locus_tag="NOA48_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0790330.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMSNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            3440..3790
                     /locus_tag="NOA48_002087"
     CDS             3440..3790
                     /locus_tag="NOA48_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0790331.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            3771..4487
                     /locus_tag="NOA48_002088"
     CDS             3771..4487
                     /locus_tag="NOA48_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790332.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            4487..5935
                     /locus_tag="NOA48_002089"
     CDS             4487..5935
                     /locus_tag="NOA48_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0790333.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(6005..6514)
                     /locus_tag="NOA48_002090"
     CDS             complement(6005..6514)
                     /locus_tag="NOA48_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790334.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(6504..7229)
                     /locus_tag="NOA48_002091"
     CDS             complement(6504..7229)
                     /locus_tag="NOA48_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790335.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(7452..9572)
                     /locus_tag="NOA48_002092"
     CDS             complement(7452..9572)
                     /locus_tag="NOA48_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0790336.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9802..10980
                     /locus_tag="NOA48_002093"
     CDS             9802..10980
                     /locus_tag="NOA48_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCI0790337.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            10996..11754
                     /gene="aroD"
                     /locus_tag="NOA48_002094"
     CDS             10996..11754
                     /gene="aroD"
                     /locus_tag="NOA48_002094"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCI0790338.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11777..12262
                     /gene="ybaK"
                     /locus_tag="NOA48_002095"
     CDS             11777..12262
                     /gene="ybaK"
                     /locus_tag="NOA48_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCI0790339.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(12333..13586)
                     /locus_tag="NOA48_002096"
     CDS             complement(12333..13586)
                     /locus_tag="NOA48_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0790340.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13703..15052
                     /gene="gdhA"
                     /locus_tag="NOA48_002097"
     CDS             13703..15052
                     /gene="gdhA"
                     /locus_tag="NOA48_002097"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCI0790341.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            15164..16510
                     /locus_tag="NOA48_002098"
     CDS             15164..16510
                     /locus_tag="NOA48_002098"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCI0790342.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16818..17204)
                     /locus_tag="NOA48_002099"
     CDS             complement(16818..17204)
                     /locus_tag="NOA48_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0790343.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5637 a         3037 c         3394 g         5163 t
ORIGIN      
        1 agcttttgga tttttacagt aattttatct taataatagc aatattatta cttctaaata
       61 tttggttttt tgataagagt agaaatgcag ggataggttt tagaaccaaa cgaagtacgt
      121 cttctgaaaa aaagtgggta tattcacaga ctatttttta cggaggggtt atttcaatca
      181 gtttactttc ttcaacactt tattctttta atgttataga cgtttccatg tcaaatttta
      241 tatctattat tggaatcctt atttctgcaa ttattacaca actacttctt gtgtttgaag
      301 agaagtcaaa aaataattaa agcaattatg ccttttagta caggaattat tacttcttac
      361 aaatgtatag cgaatgtgaa gcctgctgtt ttaattgttc tagaaaaact tttgagtgaa
      421 caattatttt atgttaggat gaattaattt ctctagagtt tataattaaa aaacttattt
      481 gaaggaacat gcttaaacca taattgtgtt tttccttcca tcagcataaa agttcacctc
      541 aaaaagagtg tacgaacaaa agttcttttt gtaaacctta aaatagattt tcctgaatac
      601 gtattgggga tttctaaatg tttgaatgtt tttttgaatg caaaatcaat gcaaaaaatt
      661 ttgtatttct ctacttttct ctccttgacc aaaataaaaa aacgttgatt taacaacgtt
      721 tttcatacat gtttatctgt ctcaaccata catatatgga gacgcatatc ttcactatca
      781 ctcataaata gtcacactcc aagatatgcg ataacaggtt tgttgccacg cattctactg
      841 gttgattgtt tatggcttta tgtggcaaca accactaccc ttagctcagt tggtcagagc
      901 agacggctca taaccgtccg gtcgtaggtt cgagtcctac agggtacatt aatgtagcca
      961 attgaatcgt tctgtgttag aattttttga agagtattat acaagctaaa gcttttcttc
     1021 attgccactc aaatgagtgg cttttttatg tatcctttta tggattaatg aaaggatgtt
     1081 tcacatagtt atacttctgt atatttgaaa agttttactt tgatttttaa atggaaagac
     1141 atttgggtta tattgtgaga taataataaa gaagagttta aagcgttccc caaaaaccac
     1201 ttccccataa gtgtgttacg ctttaaactc ttttatattt gaagccatta aaaagcatac
     1261 catataactg taaaaaataa tgggaaaaag acttataatt ggagtggtag ttaattagtg
     1321 acttattttt gattttatag cactgatact ataaaatata gatatcatca tattacacaa
     1381 tcttaatact aacttaaaaa atatcccttt tataagtatg gtgataaaat ccgttccggg
     1441 ctaccttttt taggtagcct actttaatct ttataccttt ctggatcaac gaaagtatac
     1501 ttcaaatagt cataacgccg atgatcgctc cgtgcgtctg gcacatcagt cacgatatca
     1561 aacaaaaaat acacatcttt cttcattctg gtttttgttg ccggaatttt aaagtagttc
     1621 ttattagagt aatagagatt gattaataag ctatcttcga ttgctaaaaa gaaaacttct
     1681 gaatcccaca ccttataaaa atctttgaca aatctattcg aaggatcaaa tttaaaccat
     1741 aattgtgttt ttccttccat caacataatg ttcacctcaa aaagagtata cgaactaatg
     1801 ttctttttgt aaagtaggaa tatcattgat aatatggatg gaacatatat attaaaaagt
     1861 gttctttttg aatgctattt tgaatgccat tttcattcat ttaacgaaaa tctgcgaaaa
     1921 taaaaaatgc tcaaaccctt ataaaataag gatttaagca tctagcgaaa tctgctgaaa
     1981 tctcacaatg gagacggcgg gagtcgaacc cgcgtccaaa cacatcgcca cttaaaaatc
     2041 tacgttcata gtcaactcat ttaaggattc actttacagc ttgccgagtg acaggcattc
     2101 tgtatcgcta gtctgatgtt ctctttttca acttacagac ggaaagttga aacgtatccc
     2161 actaaagtta ggacccttac tcgagcacat gggcgatgcc gagaggatct acgctaactg
     2221 tttttaggca gctaaagcgt aagagttgtt ttcgttttta gcagttatat ttaactgtaa
     2281 cgtttttacg tagacgtaac ctacgaaacg caattcaagc tcgactgtgc ctgtcgaatc
     2341 cgtaacgtcc ccgttagcta acaagggtta cgtgtatttt tcatacaaaa ttagtatagc
     2401 atatattggg ataaattcaa taaaaaagcg aatcatatcc cattatttat ataataactg
     2461 cccctttctt aagaaaaaat aagcgatttt cttaagaaaa gaggtagctt caaaaaaaga
     2521 tcttaaatca gatcaaaata cttcaatgcg tggacaattc cgccttctgt atttttcttt
     2581 gtgataaagg tagaaagttc ttttaatccg tcataggcgt tgctcatagc gattttgttg
     2641 tcgcaagctt ccaacaaggc aaaatcattc ggaccatcgc caaatccaaa agtaggaact
     2701 ttttccagct gaagttcttt ttgcagacgt ttgacacctg ccccttttga gattcctttc
     2761 ttcactgtat cgatcgagta aggaccattc cgataaaaag ttagctcagg aaaatgttcg
     2821 tgatagtatt cgtcacctga ttgagataag atcagcaaca tatttactgt gttttcttta
     2881 aagcctaaag gatcaatttc cggaacatct gaatgaatga agtcgtaagc attgatcatt
     2941 gtttggctat gaccggtaca ccagattttc tgatcgttat agtaagaaag ttcatgaccg
     3001 ttcaactgta catgatcata cattttttga cattcttctg aagaaaatgt ttgagaatag
     3061 atttcttcgc cgtctactcg aatgaaagaa ccattcatgg tgaccgcaga agtaatgccc
     3121 gcatcttcca tgatagagtg gatttctgct tctgtacgtc ctgtagcgat gacggggaga
     3181 acattgtttt cttttaatgc gttcatagct tttgccactt cgggtgtgat ttttgatttc
     3241 gcatctagta atgttccatc aagatcaaag aaagtgattg cacgataatt tgacacaaat
     3301 aaaactcctt ttttattgga ataagtttat cttaacaaag aatgaacaaa agacaaacct
     3361 ttcgtgaaga attcctgaac atattggttc agtcaacaat ttagagtata ctataagaag
     3421 agaatttagg agggaaagaa tgattttttt cagtattggt atcttattct taataattgg
     3481 cagtcttttt cggattctgc cctcaaaagg aaatctgcct ttttatgggt atcattcgcc
     3541 tcttgccgca aaaacagacg ctcattggcg gctggctcaa aagacaagcg gaaactggtt
     3601 ttttcttatg ggcttactga tggcattgat cggctattat ttaaagacat ctgggcatac
     3661 gaattatttt ctgattgaaa tgcttctgct agtatttcca attatgccta tttttattat
     3721 gacagaaaag aaattacaga aatatgacct ggaaactgga gggaacgata atgaatattt
     3781 taatgattga agataatcaa tctgtttctg aaatgatgca gatgtttttc ttaaatgaag
     3841 gttgggaagc aactttcaag tatgatggaa aagaagggct cgatgccttt ttagaaaacc
     3901 cacaacattg ggatatgatt acactagacc tgaatttgcc cacactggac ggtatgctag
     3961 taggaagaga gatccgcaaa gtttcaagta ctgtgccgat tatcatgctg acagctagag
     4021 attctgaaag cgatcaggtg atcggcttag agatgggggc agatgattat gtcacaaaac
     4081 ctttcagtcc tctgacgctt attgctcgaa tgaaagcttt gcatcgccgt agtgagttgg
     4141 cagaagcaag agaagaagca gtagtttcag atgatcattt tgatatcgag actagtcatt
     4201 tcaagatgaa tacgaaaaca cgagaagcgt atctggacaa ccggccaatt gaaggactga
     4261 cgcctaaaga gttcgatcta ttgtttactt tagcaaaaaa accacgtcaa gtattctctc
     4321 gggagcagtt gcttgaatta gtctgggatt atcagtactt tggtgatgaa cggacagtgg
     4381 acgcccatat caagaaatta cgacaaaaaa tcgaaaaggt cggaccacaa gtcatccaaa
     4441 ctgtttgggg agtcggctac aaattcgatg attctggtgt tgcctaatgc gttatttgta
     4501 tcagcaactc ttagctttct gcggaatggt cgcgttgatc ttattgatcg ttggagtttc
     4561 ttttacacaa ctgacaaaac aaacgattga agaaaacaat taccagcaac tgtttggata
     4621 tgctgaatca gttgaaaaga caacgcaaac ctatgccgat acgctcccgc agtttagtca
     4681 agatcaggcg tttcaaaatg cattgctgct gacagagcaa gtactgacag aacaaaatgt
     4741 gaactttata tttatcgata aaaacgaacg tgtcatttat ccgactaata cagctttact
     4801 gaattttacc ttaacagctg atcaatggaa aaatctgagg aatggacgtc aagaaaaatt
     4861 cacatcgaat aaaaatattt taggacaagc acaggcgacc tcttacgcac ttgtgccatt
     4921 taatttgaat catgaattct atggagcact tgtagttagt caacctgcgc gaaatatcga
     4981 taacagcgtt cgtccaatta cactgaacct gttcaaagga tttatttttt ccagtatcgt
     5041 tgcagttatt gccagctatg cttttgcagc attccaagtt aagcgtatca atcggttaag
     5101 gaatgcgacg aaagaagtga cgaatggtaa ttttgatgta cagctccccg tacatgacaa
     5161 agatgaattt gatgagttag cagatgattt caataaaatg acgaattcat tgaaagaatc
     5221 tcaagcagaa attgaagaac aagaaaatcg tcgaagacaa tttatggcag atgcttctca
     5281 cgagatgaga acacctctta cgacaatcaa cggacttctg gaagggttag aatacaatgc
     5341 aatccctgaa aatcagcgag aaaacgcgat taaattgatg aaaaatgaaa cagagcgtct
     5401 gatccgtttg gtgaatgaaa acttggatta tgaaaaaatc cgtacgaatc aaatcagtat
     5461 ggtcattaaa aaattcaatg gaacagaaac attgaaaaat attgttgcac agttagaagc
     5521 taaagcagaa gcagcaggag atacattgac attgaaagcc gttgatgata ttgatgttta
     5581 cgctgattat gaccgatttg tccaaatcat ggtcaatatt attcaaaacg cgatacagtt
     5641 tactgaaaac ggccaaatca cgattacttt agaaaaaggc tatcttgaaa cgatcatcac
     5701 gattgaagat acgggaattg gaatgtctga acaacaaatg aaaagtatct gggatcgtta
     5761 ttataaagta gatccttcaa gaaaaaatac aaaatatggt gaatcaggat taggtttacc
     5821 aatcgtgcag caacttgtac gcttgcataa aggaaaatta gaagtagaaa gcgaactagg
     5881 aaaaggaaca aaattcgctg ttcgtttgcc tgacgtagaa atcaaaaaag agtaaaaaac
     5941 aagcggtata aaagatcatg aatcgatctt ctataccgct tgtttttact ataaaatgat
     6001 tgatttagcc cgcgggctct aaacgatcaa tataaggact ttgagcaata gtagcatcat
     6061 gagtaaagag taagatacct tgattttctt catgagctaa ataagaaagc aagtggagta
     6121 gctcttggat ctccaataca ctaagttcat caaatgtatc ttcaataaca atattgtttc
     6181 gcttggaaag caaggcatga agtaattgca gctttacttt ttcaaaagac gtcaactcag
     6241 ctgccgcaca attaagcaag gaaggagaga tatcaagttt ttcttgatag gccaaacgat
     6301 cttgtttgat ttctttttcc ggtacatcca acaggacatg gtctttaaga ttcagataag
     6361 gaaacatcgg ccaatttttt tggatgatcg caaaattatc cagttttgca acaagaacct
     6421 cttttttcaa gtgctccaat attttatgct gtttttcgag aggacacaaa ataacggtca
     6481 agtgttcagc atgaatcaaa tattcaggtt tcattacgtc caggcctcct actttgcaaa
     6541 tgatggataa aaaaagtgaa agggaataga ctaagaatga gacagcatcc actgagccca
     6601 ataagagttt gggcaaatcc cttaagtata tctgtgaaaa aaagatcatt ttggaaatcg
     6661 atggtaaaaa aagtctgttg atccatcgga attgtaagtc cgcttaccga agtcaagata
     6721 tcacggatat ctggcagttc agtagtcttt aagacaagaa aattgatcct ttgaagaagc
     6781 gcttcataaa ctgactggaa gcttacgatc cacaataaaa ccaagataca acaaagaaag
     6841 agaggaaaga acagctgcca gaaaataaaa aggaataatt tggttttaga aagaccagtc
     6901 aggtgccaat tgatcaattc ctgcttgttt tgcctgactg aatagtaaaa gaaaaagata
     6961 aaaaggaagg caaatagaaa aaataaactg aatatgcctt ttatataaaa tcggctagct
     7021 aattctaaag ccggaagaag ctctgtagat gcagaagcgc caataaatga aagccgatct
     7081 tggacttgat tggctaaagc cgattgcaaa tggtaaagag tcaggcatgc tatcaataaa
     7141 aaagcagaaa agcttgaaaa taaacaatag agtattgtct gctttttgta ataaattaat
     7201 cgagcagtag catagcggat tattttcata cttttcacct ctataaaaag tatagaaaat
     7261 gaatatgaat aaagtatgaa attcctttag tgaaatcacg aattaaaacc agaaaatatt
     7321 ttgtaaaaag caagaggttg tgaagaagct gccctattct attaccgtag atgcaagctt
     7381 ttgaacactg tttattcgaa aagaggagca gcgacaataa ttttgtcgct gctcctttta
     7441 aatttatttt atcattcgga agaacttgtg gtcgttccgt gaagttcttg gtacgtttgc
     7501 gttttataaa gatcaacagt tgattgtccg ttgtgttcac taaagacact agttgacttg
     7561 tcaccaagag atttttcagc ttcttttaat ttctctaagc cattcttgta gtcataatca
     7621 ctggtatcaa ttgggtctaa tccactattc gtatagaacc gaagaagatc accattattg
     7681 atttggtcag aaacagctaa ctgtttatca actttttctt tcagtgaatc aatttcattc
     7741 tgtacttcct cagtaggttc agtaatagct tcaccagttt cgttactata gatcgtacca
     7801 ccgtagtaag tatattttgg tgtaacaaaa tcaccatcac ggaaagaaac aagctgttca
     7861 tgatctttcg agaatagatc ttgtcctaac tgaatataat tttttgtatc tacacctagt
     7921 aagtgaagta atgtaggcaa ggcatcaact tgtccgccgt aagtgtgatt gattccgccc
     7981 tgtgtttgtc cagggatatg gatcatataa gggacacgct gcatttgtgc attgtcgtag
     8041 tttgtccaag tagaacttgt ttttccaact aattcagcta gatttttatt tcttgaattc
     8101 gagacaccgt aatggtcacc gtaaaggacg atgactgaat tatcatacaa gccgctttct
     8161 ttcaaataat tgaagaattc ttgtacggcg gtatctaaat aattggctgt cgcaaagtaa
     8221 ccgttgatcg tttcatcatt tgtattggct aacgggaatc ctgcttcgtc attggtgaat
     8281 tttgaataag gataatggtt agatacagca atgaattttg aataaaatgg ttgttgcaga
     8341 cgttccaagt attgtacgga ttgttggaaa aatggtttat catgcaaccc gtattggaac
     8401 gaattgtcat cattaacatc ataataagaa gaatcaaaga aataatcata tcctaaattc
     8461 ttgtatgtct cgtttcgatt ccagaatgta ccagcgttcc catggaatac cgcactaatg
     8521 taaccttgtg tttgacttaa aatatcaggt gcagcttgga aagtattttt tccgcctaat
     8581 tgtgtgaaca aggagccttg attcaagcca aacaatgaat tttccatcag cgtttccgca
     8641 tcgcttgttt ttcctgcttt tacttgatgg aaaaagttgt caaaactgaa cgtgctgttg
     8701 ctgtggtaaa gactattgat gaaaggtgta acttcatgct ggagaccatt ctcatctgtc
     8761 aatttataat cgatcaggaa ttgctggaag ctttctaaat ggatataaat cacatttttt
     8821 cctctagcga gcccgaacaa atcgtcattt ggtgctgcat aatgttcttt tacataattt
     8881 tctacttctt tcatatcatt gggacttgct tctgcccgca cttggtttgt ctggtaagtt
     8941 tgaacaccgt cataaaccat gaaagcattc aagccaagat atttgaccaa ataatcacga
     9001 gagaatgttc gagtcagcaa ttctggacga tcagcttccg ccataaaaag atttcctgag
     9061 aaaatcataa ctgctaatgt agagatcgca aaagccattc ttgctcggat cgggcgaggg
     9121 tccaacttga ttttttttgc aatcagcaga acagtcaaga taataaaatc gatccaatag
     9181 atcacatcat atgggcgaaa cagtcgaatg gcactttctc ccagaccact cgctactttc
     9241 ccagcaccta aaatcgtgtt gatcgtaatg aagtccgtga attctcgata ataagtgaca
     9301 ttcgaaaaaa caagcaatgt caaaagaaaa taaatgacca tcatcgtgat ataagcaact
     9361 ctagggcgtc tgatataaag agcaattcca agtaataaca atgtagttgc aatagggttg
     9421 ataaacaaga taaagtattg aatgccactt tcgattccga gatggaaatc aactaaatag
     9481 gcaaaaatcg ttttcaacca aagtaaaacg actagtaaag aaaaaaatcc gagcctctta
     9541 ttcaaaaagg caggtgtttt tatacatttc aagataatct tcctttctgc acttcttaat
     9601 cacagaagtg tcctgaaacc atgttacaca gctcacttat tctcatttat tttactagta
     9661 tgacaatata gtgtcaattg aaaccagaag tttatgctgt ttcattaagg ttttctttaa
     9721 gcttcatgaa aaaatgagca gtaagacaag tcctatgttt tttgttatac ttgggaagag
     9781 aaagctaaag caggtgaagg aatgaaagta aaagtaaaaa aaagagcaag caatcgattg
     9841 aaaaaaggat atccactgat ccaaaaagaa gaccttgctc atccccaaaa agaaaccacg
     9901 caatgggtgg aattagttga ttcgcaaaac caatttatcg caaaaggata tctaggaaag
     9961 cagaataagg gaatcggttg ggtattgagc cagcagaaca tcccatttga tcaatctttt
    10021 tttgaagaat tttttgtgaa gtcaaaagaa aaaagaactt tctttttttc agatgattct
    10081 actaccgctt ttcgtatatt caatggagaa ggagacggga tcggcggtct gattgttgat
    10141 tattatgcag gttatgctgt tttttcttgg tataacgaaa cgttatatgc acatcgtgaa
    10201 ttattgattc aagcttttcg tgaaatctac ccggaaatca taggaggcta tgagaaaatt
    10261 cgatttgaat cagtaaatct gcctgagagc cagttcattt acggaaaaga ggcaccggaa
    10321 cccttgatcg taaaagaaaa cggagtaaaa tttgccgttt atttaaatga aggattaatg
    10381 actgggatct ttttagacca aaaagaagta cggggatcat tagcagaagg tttcgcttct
    10441 gggaaaacag ttttgaacat gtttagttat accggcgcct tttctgttgc tgccgcaatg
    10501 ggaggggcaa tcgaaacaac aagtgtcgat ctagcaaaac gcagtttaaa aaaaacacag
    10561 gaacagtttg aagtgaatgg tttggatgtc gatcagcaaa aaatcattgt tatggacgta
    10621 ttcgagtatt tcaaatacgc caaaagaaaa caatttttat atgacatgat tgtattggat
    10681 ccaccaagtt ttgccagaaa taagaaaaaa gtctttcgcg tagcaaaaga ttatggggaa
    10741 ctggtcaagg atagtctgga tattttagca gaagacggga tacttattgc gtctacaaat
    10801 gctgcgaatg tctcgataga acaattccaa acaatgattg aagaggaatt ccatgccaaa
    10861 aatgtttctt ttgaacaact tgctttatat cgtctgccaa aagatttcca gacgacggat
    10921 acctttttag aaggcaatta tctgaaagtg tttgtttatc aaattaaaaa taaccattag
    10981 aaggagcgat gcagaatggt tcgggtaaag ggattgaata taggaagcgg tagaccaaag
    11041 atttgtgcgc ctcttatcgg ggccgtccga gaggaagtat tacgtgaagc agttcttgca
    11101 cgtgaagcag gggccgattt agtcgaatgg cgagtcgatc attatcgtga agttttttct
    11161 tttgatgaag tagcagaaac attggttctt atccatgaga tgcttgatgg actgccgtta
    11221 ttatttacgt ttcgtacctt agctgaaggc ggagaacaag acatatcgat ccgtcagtat
    11281 cgcgaccttt atgaacatgt gatacacaca ggattagtag atatggtcga tatcgagttg
    11341 ttcaaagtag aaagtctagg aaaaagactg atagaggaaa tcaagtcttt aaacattcct
    11401 ttaattatca gtagtcatga ttttaaagaa acaccagcag accctgtctt gctttaccga
    11461 ttgaatgtta tggaacattt tggagccgat atcggaaaac tggcagtaac tcccaataat
    11521 gaacgagatg ttttgcggtt gatggagttg actagacggg caaatgcttt tgtctccatg
    11581 cctattatta cgatgtccat gggaaatctt ggtaaaattt ctcgtctggt tggcggaacg
    11641 acgggttccg ttatgacatt tggttcctta agcagcgatt ctacttctgc tccaggacaa
    11701 ttaccggtca aagcattgaa gcaaattatt caattattaa atgaaccgtt gtagaacaag
    11761 tttgaggtga tattttttgg caaagaaaaa aatagtaaaa acgaatgcaa tccgtatggt
    11821 cgaacaaaaa aagattccct atacagagca cgaatatgag tgggacgaaa gccacctaag
    11881 tgcgtcatcg gtcgctgaac agcttccaga aagccaatct cgtatattta aaacactggt
    11941 tgctgtgggc aatgtgacgg ggcctcttgt tgctgtgata ccgggagaag ccgaattgaa
    12001 tctaaaaaaa ttagcaaaag tttcagggaa taaaaaagta gaaatgctcc atttaaaaga
    12061 tttggaagca acgaccggat acatacgtgg tggctgctcg cctataggta tgaaaaaact
    12121 atttcctact tatttagatc aaattgcaga aagctatgaa caaatcattg tctcggctgg
    12181 cagaagaggg ctacagatgg agttagcacc tcaagatatc tgtgcattaa cgagcggaca
    12241 atttgcagat ataaaacaat aaatcatacg tataaaagaa agaaggaggc cgggatgttg
    12301 tttgtccagt ctccttcttt cttttttata cattatgctc tttgcccggc attcattcct
    12361 gctacatgcc ctgtagcgaa agccgctgtg atattaaagc cgccagtata accattgaca
    12421 tccagtaatt ctcccgcaaa atacagacca tcaatgattt tactctccaa tgttttagga
    12481 taaatttcct ttagagaaac ccctccgcca gttacaaatg atttctcaat aggaaaagtt
    12541 ttgttgattg atagcttaaa ctctttgcat agttgaacaa aatcttgaat ttgtttttga
    12601 gaggcttgtt gtcctgtcag atgatccatt tcaagccgct caagaaagaa aactaacaat
    12661 cgctcaggca atataccatg ccaagcattg accaagttct ttttggttgc tttacttttt
    12721 tctgtcaata tatgaataag ctcttgtttg gtttgtgtag ggaaacaatc cagagaaagt
    12781 gtcactggtt ctcccgtttt ctctaattct ttattgacaa aacttgaaca acgcagtgca
    12841 gccggaccag aaataccgaa atgggtgaaa agtaaatcca tcgtatgttc agtcaataca
    12901 cgaccttttt tatttaaaac gcgtaaagtg atgtcttgta aagaaagccc ttgaagtgtt
    12961 ttctcctgaa tatacggttc atccgatatc aagggggact ctgtcgcata aagaggcgtc
    13021 accgtgtgac ccactcgctt cacgatcttg tacccatctc cagtagaacc agtagatgga
    13081 taagtccgtc caccagttgt taagataatg gcaggagcat ggaactcttc gaattccgtg
    13141 cgtataccgt aaattttatg ttctttgtgg atcaatttct ctactcgagt agagaataga
    13201 agcgtcacat ctagttcttt cagacgattg agcaatgctt cgataatcgt ttttgattta
    13261 tttgttacag gaaacatccg tccatgatcc tcttctttta aatgtacgcc ttgtgattca
    13321 aagaagttca tgatatcgaa attattccat tgcgcaaacg tactatataa aaactttcca
    13381 tttccaggaa tatgtgcaat caaatcatca acaggacgat tgttcgtaac attgcaccga
    13441 ccaccacctg tcatcagtag tttttttcct gcttttttgt ttttttcgat caagagtacg
    13501 cgtgcgcctt gttcagctgc actgatcgct gccatcatcc cgcttgttcc agcgccgact
    13561 acgatcacat catacagttt ttccattccc tcacctcaag gaaagtgtag catatctgaa
    13621 gaaagaaaac agaaaaaaat gttttgagcc aaaagagaaa atgagctaaa atgagggaag
    13681 ataagcaaag gagcgtggaa cgatgacaaa cgcaacagaa tatgttcaag caattcaaga
    13741 aaagctacat caaaaggatc aagggcaaga agaattttta caagcaatcg atgaattcat
    13801 gcccacggtt atgtcttttt tggacactca tcccgaatat atcgaaaaga atatcttaga
    13861 acttttaacg gaaccagaaa gagttattca atttcgagtg ccttggcaag atgatgaagg
    13921 aaactggcga gtaaatagag ggtaccgtat ccaatacaac tcagctatcg gcccttataa
    13981 aggtggattg cgcttccatc ctagtgtcaa tctaagtatc ttgaaatttt tggcttttga
    14041 acagattttc aagaatagtt taaccggtct gccaatcggt ggaggaaaag gcggaagtga
    14101 cttcgatcct aaaggaaaat ctgataatga gatcatgcgt ttttgtcaaa gtttcatgct
    14161 ggaattgtca aaacatatcg gcccatcgat tgatgttcct gcgggagata tcggtgtagg
    14221 agctagagaa atcggctatt tgttcggcga atataaacga ttgaaaaaat atgatactgg
    14281 tgtgttgaca ggtaaacctt tggatttttg gggaagtaag atacgtacgg aagctactgg
    14341 ttatggatta gtgtattatg tcaaacatct attgaacgaa gaaaaagatt catttaatca
    14401 aaaaacagtt tttgtttccg gaagcgggaa tgtagccatt tatgcaatcg aaaaagtgca
    14461 agagctaggc gggaaagttg ttacatgttc agattctagc gggtacatct atgatccaga
    14521 aggaatagat gtgaaactat tgaaagaagt caaagaaatc aatagacaac gtttgacgga
    14581 atacgcaaac caacgtcctt ctgctattta tcatgctgga gaatctgttt ggacattgaa
    14641 agaaaaagcg gatatcgctt tgccatgtgc tactcaaaat gaaatagacg aaagcttggc
    14701 cgaaatctta gtagaaaatg ggatcaaaat cgtagcagaa ggcgctaata tgccatgtac
    14761 agtaaaagct gtttctgttc ttcatgaagc aggcgtgtgg tattgtccag gaaaagctgc
    14821 taatgctgga ggagtagcag tatctgcttt agaaatgagt cagaacgtcc agcgattgac
    14881 ttgggaaaga gagcaagtgg atgagcagct ggatcaaatc atggaaacga tttaccatac
    14941 gtgtcgccaa acagcagccg agtacggcga cgaaaaaaat ctgcttcttg gagcaaatgt
    15001 tgctggattt gaaaaagttg ccaaagcaat ggcagcagaa ggtttagttt gaaaaatgaa
    15061 actttcttgg aaatattgtc agcattttgt ttatttgctt gaaaaataat aaaaaaaaac
    15121 gtaaagtatt acctgtagag taaacctata aggaggagaa caaatggcac acattcattt
    15181 tgactattca aaagtagcac cgtttgtcaa cgaacaagag ttagggtaca tgcaaagcca
    15241 agtaacagca gcccacaacg aattacggga aggtactggc gcaggaagcg acttccgcgg
    15301 ctggatcgat ttaccaacga actatgacaa agaagaattt gcacgtatca aagaagcagc
    15361 taaaaaaatc caatctgatt ctgaagtatt agttgttatc ggtatcggtg gttcttattt
    15421 aggcgctcgt gcagcgatcg acttcttgaa tcacacattc ttcaatttat tagatagcaa
    15481 cacaagaaaa gcaccacaaa tcttctttgc cggaaattca atcagctcaa catatattgc
    15541 tgacttgatc gaagtaatcg gtgatcgcga cttttcagta aacgttattt caaaatctgg
    15601 aacaactact gaaccagcga ttgcgttccg tgtattcaaa gagcttcttg ttaagaaata
    15661 tggacaagaa gaagcaaaca aacgtatcta cgctacaaca gataaagcaa aaggtgcagt
    15721 taaagtagaa gcagatgcag aaggttggga aactttcgtg attcctgatg acatcggcgg
    15781 acgtttctct gtattaactg ctgttggttt gttaccaatc gctgttagtg gtgcagatat
    15841 cgatgcattg atgcaaggtg ccgctgatgc aagcaaagca tactcaagcg acaaactaga
    15901 agaaaacgaa gcttaccaat acgcagcaat gcgcaacatt ctttaccgta aaggcaaagt
    15961 aactgagttg ttgatcaact atgaaccagg aatgcaatac ttctcagaat ggtggaaaca
    16021 attgtatggt gaatctgaag gaaaagacca aaaaggcatc tatccttcaa gcgcaaactt
    16081 ctcaactgat ttgcactctt taggacaatt catccaagaa ggacgtcgca atatttttga
    16141 aacagttgtg aaggttgaaa aacctcgtaa atcaatcaca attcctgaac aagcagaaga
    16201 tttagacggt ctaggctact tgcaaggaaa agaagtggac ttcgtaaata caaaagcatt
    16261 tgaaggaaca ttgcttgctc atacagacgg tgacgtgcct aacttgctag tcaaaattcc
    16321 agaaatggat gcttatacat tgggttatac aatgtacttc tttgaaattg ctgtaggtat
    16381 ttcaggttac ttgaatggaa tcaacccatt cgaccaacca ggtgtagaag cttacaagaa
    16441 aaacatgttc gcacttctag gcaaaccagg ctttgaagat cttgctaaag aattgaacga
    16501 acgcctgtaa gataagggtt tttcgctaga tttaaataat cagtgataga aacatgttcg
    16561 ctttaaaatg aaaactggta cccatttagg tactcaaaca tactgcatcg tttattcaga
    16621 ataaggggct gtgacaagac gtttgtcaca gtcccttgtt tgtatagaaa tcgattgatt
    16681 gccttgctct ttagtttgtt ttaggacttt aagaacagtg aggctgactt cgaaggttaa
    16741 ttctgttttt ttgttttcta gaatcagtaa gcaaaaaagc actcacttcg agtgcttttt
    16801 tgcgatatat tcttagctta agataggcct aatttttctt ttacagatga gggtacctta
    16861 tcgctggtaa ttactttttt ctctatgatc cgcttttcgc ttgctttcaa ctgcaagatc
    16921 gttccttcgg ggtaagcaga accattggca gagtcaccag aagtaatgac atcgaaatct
    16981 aactgtcttt tttcaccgtt ttcagcataa gcatctacgt tgtatttaaa acctcttcca
    17041 attacttccc cattatctgc tttgatatca gtttctgcag gcattggagc tttgactacc
    17101 gcataataat ctttacctac ataagtagac tgatagtagt cccaaccttt ccatcctata
    17161 aaagcaatca atatgataac gatcaaccct aaaatttttt tcatgaaaga tctccttttt
    17221 tatttttatt a
//
LOCUS       DAIGQM010000061        17007 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.063, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000061 DAIGQM010000000
VERSION     DAIGQM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.063"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..126)
                     /locus_tag="NOA48_002100"
     CDS             complement(<1..126)
                     /locus_tag="NOA48_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCI0790344.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="NOA48_002101"
     CDS             complement(230..541)
                     /locus_tag="NOA48_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0790345.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="NOA48_002102"
     CDS             complement(543..740)
                     /locus_tag="NOA48_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCI0790346.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="NOA48_002103"
     CDS             complement(1134..2861)
                     /locus_tag="NOA48_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCI0790347.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="NOA48_002104"
     CDS             complement(2854..4047)
                     /locus_tag="NOA48_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0790348.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="NOA48_002105"
     CDS             complement(4234..4878)
                     /locus_tag="NOA48_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0790349.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="NOA48_002106"
     CDS             complement(4972..5106)
                     /locus_tag="NOA48_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCI0790350.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="NOA48_002107"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="NOA48_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCI0790351.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="NOA48_002108"
     CDS             complement(7237..7710)
                     /locus_tag="NOA48_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCI0790352.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="NOA48_002109"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="NOA48_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCI0790353.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="NOA48_002110"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="NOA48_002110"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCI0790354.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="NOA48_002111"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="NOA48_002111"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCI0790355.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="NOA48_002112"
     CDS             complement(11757..12896)
                     /locus_tag="NOA48_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0790356.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="NOA48_002113"
     CDS             complement(13205..13918)
                     /locus_tag="NOA48_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCI0790357.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="NOA48_002114"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="NOA48_002114"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCI0790358.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="NOA48_002115"
     CDS             15107..16639
                     /locus_tag="NOA48_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0790359.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="NOA48_002116"
     CDS             complement(16830..>17007)
                     /locus_tag="NOA48_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790360.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAIGQM010000062        16856 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.064, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000062 DAIGQM010000000
VERSION     DAIGQM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.064"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..833)
                     /locus_tag="NOA48_002117"
     CDS             complement(<1..833)
                     /locus_tag="NOA48_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790361.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(847..1644)
                     /locus_tag="NOA48_002118"
     CDS             complement(847..1644)
                     /locus_tag="NOA48_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0790362.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1677..1961)
                     /locus_tag="NOA48_002119"
     CDS             complement(1677..1961)
                     /locus_tag="NOA48_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCI0790363.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1958..2959)
                     /locus_tag="NOA48_002120"
     CDS             complement(1958..2959)
                     /locus_tag="NOA48_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCI0790364.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2961..4028)
                     /gene="gnd"
                     /locus_tag="NOA48_002121"
     CDS             complement(2961..4028)
                     /gene="gnd"
                     /locus_tag="NOA48_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCI0790365.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            4027..4875
                     /locus_tag="NOA48_002122"
     CDS             4027..4875
                     /locus_tag="NOA48_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0790366.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            5521..5727
                     /locus_tag="NOA48_002123"
     CDS             5521..5727
                     /locus_tag="NOA48_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCI0790367.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5929..6930)
                     /locus_tag="NOA48_002124"
     CDS             complement(5929..6930)
                     /locus_tag="NOA48_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0790368.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(6935..8847)
                     /locus_tag="NOA48_002125"
                     /pseudo
     CDS             complement(6935..8847)
                     /locus_tag="NOA48_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9015..9521)
                     /locus_tag="NOA48_002126"
     CDS             complement(9015..9521)
                     /locus_tag="NOA48_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0790369.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            9681..10121
                     /locus_tag="NOA48_002127"
     CDS             9681..10121
                     /locus_tag="NOA48_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0790370.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(10147..11304)
                     /locus_tag="NOA48_002128"
     CDS             complement(10147..11304)
                     /locus_tag="NOA48_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790371.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(11307..11663)
                     /locus_tag="NOA48_002129"
     CDS             complement(11307..11663)
                     /locus_tag="NOA48_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790372.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(11961..12935)
                     /gene="sgrA"
                     /locus_tag="NOA48_002130"
     CDS             complement(11961..12935)
                     /gene="sgrA"
                     /locus_tag="NOA48_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCI0790373.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(13131..13970)
                     /locus_tag="NOA48_002131"
     CDS             complement(13131..13970)
                     /locus_tag="NOA48_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0790374.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            14155..15042
                     /locus_tag="NOA48_002132"
     CDS             14155..15042
                     /locus_tag="NOA48_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0790375.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(15636..16331)
                     /locus_tag="NOA48_002133"
     CDS             complement(15636..16331)
                     /locus_tag="NOA48_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCI0790376.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(16315..16713)
                     /locus_tag="NOA48_002134"
     CDS             complement(16315..16713)
                     /locus_tag="NOA48_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0790377.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         5039 a         3423 c         2595 g         5799 t
ORIGIN      
        1 taaaatccgt catcatagtc atcttcgtca tcaaaagatg ctgaattgtt attgcttgtg
       61 gcaggctgta cttgtttccc tttttgcgac tggacaaaga tcaaagcgat aataatccca
      121 aaaatggcat aagtaaccat cgtaatatct aaagatttca aaacaacact cataaaataa
      181 gcaaggaaga aaaagaccag ataatctttt cgaccgataa cgtatacagt tgtcgcgata
      241 ccgattgccg ctaaccctcc acctactact tcaagaatgt ggataacgac tgttccctct
      301 aaagctttga ttacatcagc gatcaatggc gcccctaaat ataaagcaat gaaaacaagc
      361 ggaacgaata ataaaaatga ggcaaccgtt ggataaagaa taattgatcg ggccatagct
      421 tttgtattca aatcttctac agctttgtct gtatatttac ctaaaaaagt attgatgaaa
      481 aaacgaaact gatacaagta acttccgagc aatccgactg gcaccgcaac ggcaatcgct
      541 gcttctggcg acagatcccc taataatgcg actggtactg cgatagctgc tgcaatagat
      601 ggttcagctg gcattgatcc tcctggagaa aaaaccccca tataaatcat ttgcaaagcg
      661 gctgtaacaa tcatcgcttg tgcaacttcc cccatgatca acccgacgac taatccagtc
      721 atcaaaggag aaaaacgtaa ggtcaacgtg gctcctccac ctaaccagcg ggacataacc
      781 gcggctaccc ataaagcaat caacaaactt tgtactacac ttaatgtttc catgtgtcct
      841 cctccttcag atctttctga tataaccttc cagttccatc attgactgta tcagtgattt
      901 ctgtgttacc tctataggaa tcaaatgcac tttctctttc gaatcaataa attcagccat
      961 tttatctatt atctgtttat ctttcggaaa taatcccatt tgttctagag aaaccggcag
     1021 ttctaattcc cgatacaaag gatataactc gtctattttt tcccagcgac cttctagtgc
     1081 cagttgatag aaaatcccat acgctacttt ttctccatgt agaaaacgat ggctttccgg
     1141 aatatattta ctgatagcgt catgcatagc atgtgctgcc gcatttcttg cgtatttatc
     1201 tcctaatcct ccaactaaac cagcaacagc aaagataatc tctgaaagct gtttgaactc
     1261 cgatgtcagt tttctttgtg ccatatcttg gattgcttta gcagaatgat tcaaaatctc
     1321 ttctttgcag atcttcgcag tatcttgtgc tagcttcaaa aatgattcat cttgcaaaaa
     1381 atcttgttct aagatgagct cagattcata ccattttgct agtgtatctg ctaacccggc
     1441 aatgaaatat ggaacagggg aatcaatcac taattgggga tctgttataa aaaaagcagc
     1501 ttgtctgtaa aagtgttctg ttttcccttc tgcttgtcca ttctccttat acatgacagc
     1561 aagaggtgtc catggagcac aattactagc taaagtaggg atgactccga aatcgattct
     1621 tgcaagattg gcactataac ccactagatc ggtcagtttt cctccgccaa cgccaactac
     1681 gaaatcgatt tcattttttt gatgattgta gctattcgtc tggcttcagc ataactacat
     1741 tctccagaat aacgatgata aaaaaattga atcgtttcgt cattcaaaaa tactaattta
     1801 ggtagcgcct tttcccatga taccgttccg tgggtgacca gtactctttt cgcgccgtat
     1861 gatttcaaga gatcagaaac ttttgaaata ccaccttctt catataaata aaattgaggg
     1921 cctgttttca cttttaaacc gttcaccatt ttcttcatca tccttttata tagttgctct
     1981 ttgtctggac agaacgttca ggaagaaggt gctgactgat ctgttcgaca tctctgacac
     2041 atttttcacc cattgcttct aaacattccc ttgtgtaggc cgatatatgt ggcgtaatca
     2101 ctacttgttc aaacgctaaa tacggatgat cttgacgtcc cggttcttct tctaaaacat
     2161 ctgtggcata tcctgcgatc tttccgcttt tcagaccatt aatcatcgct tcttcatcaa
     2221 ctagagcgcc tcttgcacta ttagatagat aaacattttc tttcatctga tcgacttctt
     2281 tatcagaaat catgtgatag ttctcttctg tcaaattcgc acataaacaa atgatatctg
     2341 attgttccag taattcttga agttctactt tttttgcacc aaagctttcg atgtataaat
     2401 ctgatttgta aggatcataa gctagaacat cacagcgaaa accgttacgc aaaatttcga
     2461 ttactccgct tccggtattt cctgcaccaa tcacaccaac tgttttgtta aacagcgtcc
     2521 taccgacgaa ctccgcccga tcttcccatc gatcgtcctt gactcttgct tgtgcttgtg
     2581 tcgtgcgtcg aagcatggac aacaaattag ttatattatt ttctgctaca gcatttcgtt
     2641 caactaaagc aggtatgata gatacgattg tctggtgttc ttttgctgct tttaaatcaa
     2701 tattgttgta accaatacca tgtcgggaaa tcaatagcag ttcatctttg ttttcaaaaa
     2761 aatctcgtcg aaaaaatggc gtaacacttg caataatgat attgaatcct ttaagtaact
     2821 ccgctagttc ttttcctgga atctcttgat caacagtaaa gaaatgaacg tctccaactg
     2881 actttaatct ttccaagtgg tgtggaaaga ctcttccgaa actgctggaa ttaacgattg
     2941 ctatatgata atctggcatt ttactcaccc ttttcaacta tttcatgtcc gccaaaccca
     3001 tttcttagtg ctgaaactac ttttgctgaa aaactatctt cttcctgtga aagattcctc
     3061 atgaacaaac tagttgcaat tactggaact ggaacagcca tttctagcgc tgtttcaacc
     3121 gtccattttg cttcacctga tgcagaaacg attccccgat aattacttaa attgggatgt
     3181 tcgtttaact gatcttccat gatttccatc agccagccgc gaatcaccga accatgattc
     3241 caaacacgtg cgacttgttc caagtcaaaa gcatactcac ttttttgtac aagttggaat
     3301 ccttcaccga ttgcttgcat cattccatat tcgattccat tatggatcat tttcaagaag
     3361 tgtccgcttc cggatgcacc agcatacaga tatcctcttt caattgctac atctttgaat
     3421 aattgttcca cggatagaaa agtttcttta tctcctccaa tcattaagca ggcttgatgt
     3481 cgtgctcctt cgattcctcc agaagtccca caatccaagt aaccgatttc atttttctga
     3541 aactcttctg ctcgacggat tgaatcttta taataagagt ttccgccttc aataataatg
     3601 tctcctggtc cgagttttgg aaaaagtttt cttaacatgt tttcggttat ctctccagca
     3661 ggaagcatta accagatgat ttttttctgc tcaaaagtag ctagaaattc agagatctct
     3721 tgataagcag gaatgtcatt ttctcttgcc tgactaacag ctgtacttga aatgtcgagt
     3781 ccttgtactt tgtgatggtg ctcttttaag tttaaagcta aattcaatcc catttttccc
     3841 aaaccaatta caccaatttc catgatagcg cctccatttc ttataccctc attatacaaa
     3901 aaaatttttt tgtaaataga ttttacaaaa atattttttg tttgattttt tcctactctc
     3961 cttgtatctt taacattaat gagaacggaa aaaatgataa tcttattatg aaaatgagga
     4021 attctcatga gcgtctccat aagactacaa atcaaaacaa tgtacaacga cttcagccca
     4081 aaagaacagg ctatcgccga ttatatttta gaaaatccaa gcaaagtaag tcatagtcct
     4141 attagcaatt tagcaagtga actgggcatt gctgactcta ctttttttca atttacaaaa
     4201 aaacttggtt ataatggatt taaagatttt aaaatggcca tgttgatcca agaaaatgat
     4261 ctatctgcta tttctatcca cgaaaatatt cagaaaacag atactgagct cactatggcg
     4321 caaaaggtgt tcgagtctag tatttcaact ttaaatgaca caaaaaagtt gttacaacaa
     4381 aaggatctaa aaaaagcggc tactattatc aatgaatcta aacgtgtcta ttttttcggt
     4441 gttggcggtt cagagattgt agcaactgac gcttatcata aatttttgcg ttcccctatc
     4501 gcaacttctc acagcacgga ttaccatatt caattgatgg aagcttcttt attgacggaa
     4561 aaagactgtg ctgttttgat ttctcacaca gggcaatcaa aagaaacaat ccatattgct
     4621 gaaaccgtaa gaaaaactgg agcaaaaaca atcgttatta ctagccaagc taattcttcc
     4681 cttgctaaac ttggcgatgt cgtttttatt tctatttctg aagaaacaga attccgatct
     4741 gaagctttag cttcccgtat ttctcaacta agcattttgg actctctata tgtgattttg
     4801 atgttttaca acgaaaaaga atcacgtcgt tctatcgcta aagttcgaca tactatttct
     4861 gaaatcaaag aatagcacca taacagaaaa agcgaaaaat ccataaaaca aaaaaagcca
     4921 ctaccaaata tttggtagtg gcttttttgg ttctgcaagg gtggtacaga acatcaatag
     4981 tcggtgggtt agaacgtatg tcatcgcatc tttggagaag gttgtattgg tattattcga
     5041 gttacttgtt agatgcgata acaaagttag tatacagtag taaaaaattt atcttttctt
     5101 ttttttatta tttttgtttc ttattttcta aaaaattaaa aaaaattttg gtgaattaag
     5161 tatttccttg ataacactgg cttttggcct cattttaggt tatcatttgt aattttattt
     5221 cacagttgat atgattgtta tgtaaaataa aaaagtttag gatacatcga atttttgggg
     5281 aaattctttt gggggtatcc taaatctttt ctattatatt cccatatttt ctattattgg
     5341 tctagacgta tgatggtaaa ctttgtacct atctgattgc tgaatcatta attgcttatc
     5401 attagccatc tttgtttcaa gttcgctaga tgatcatttt attcacatcc taacaaactt
     5461 gtcacattta tagattctta atctatttat catacaatta taaaaaagga ggtgctgctt
     5521 atgaaagcta tccatatttc tttgcttttt ttcgctagtg cattgatttt atttgctatt
     5581 catctttgtt cccagcctta tatcaataac aacggaatat tagtggaacc agcattcttt
     5641 tgcttaccac tcggcttttt gtcccttctt gcctccgcag gcttcggatt tgttgctttt
     5701 tttaaacgat caaaacaaca aatctgactt ataaaattta cgtaaaagag atcgtgacaa
     5761 taatcgtgtg atattcccaa atttcgaata aaaggtgccc cttgccatct ctaactcctc
     5821 agtcacaagt tacaatattc ataaaccatg aaaagcttgt ttattgaaat tgctccttgt
     5881 gacttggagc taagtgacag attacaacct cttttgcatc ataagacttt actccttgaa
     5941 aaacattact aacttttgat atgtttcttg cgcttgttta ttgctgaaat caaactgata
     6001 ttcatggttc aaaacagcat ttttctccgc ataatctact tttgtgactt tcacccccgc
     6061 tttctcaaat acagaagtta cttcttccat ttgtttcgta aacgtatttg tatttccatc
     6121 cgttaagaat gtgttttgcg tccaacgatc cgcatgtctg accaaggcta aacttttgac
     6181 cttctctgat tgttcaaagt ccttattatc aaagtaagcc catccacatt tttcataaag
     6241 aaagctagag attttatcac ttacttgagt aagtgcagaa ggatccaaca gaccagacaa
     6301 agaaataaac ttcgtaatct gcttgttctc caaagtcgga tcaagatgat cagctttttt
     6361 aatttcttca ttttgaagtg ctaacaaata ttctccacta atttgtgcac ctgccgaatt
     6421 tccaccaatc gaaatattcg accaatctgc ttgatctttt atctcttttt tagctgcttg
     6481 aatggcttcg ttcaattgga taactggtgt aggatgtttt gcttccggtg atcgttcata
     6541 atctatattt acgatgattt gctgcgtgtc tgaacataga tattccaaat aatcacgaca
     6601 atcattttta tcccctccta catatgcgcc tccatgcatc cagaaaagaa tcggtaattt
     6661 tttcttttcc actttcggtg tgtagatatc catattatta tttttgtact ttgaaggata
     6721 ggatatttct ttttttatat cgatttgttc gattttttgc tggaaatcat ctggtcgggc
     6781 atatacttgt tctttttcac ttgtgtcaaa ttgttttcta acaagcaagc taatcggctt
     6841 tggtgtgatt tgattaatca aaaatacagt gactaaaata actacgatga taactggtac
     6901 tgcaatcact attcgcttga accatttcat tcatttaccc tctctttctt cgccaaatcc
     6961 atgtgataat cgtgctaaca gataaaaatc cacctgaata aatgagaagc gaatgtttct
     7021 tttctccagt tttcggcaac attctttttt tgcatctgtc tttttttgta ctttcactgt
     7081 catctgaatc ggttgcgtat catcacttga ttgatcctct cgaggttcat tctttccctt
     7141 attgtctgca ttctctgtcg gatcttgctt ttttggtgga gctactggga tttttttgta
     7201 atagaaaata atagttggta tcgtctcatt aaaaatccct tcagtcggtc cttcaacatt
     7261 tgctaattcg tatccttcga atgtcttttg ctctgtcata taattttctc cataagctcc
     7321 gtaaagctgg atttcgtcct ggtctttgag tagactttta ttgttttcat ccacatactt
     7381 tacgtttatc tgatcatgga acactacttt caaaaagtcc gttacatgtt tcgtgtaggc
     7441 agcatggtca acttcctgtg cctttccatg ccctgctcct tctactaata aaagatcttt
     7501 ataccctcct gataactcat ataatttttg cgcgttagac acaggtacta catcatctgc
     7561 tgttccatgg ataatcaatt taggcaatga atctgacatt ccaatcgtag gtagagcagc
     7621 ttttgtatcc aaatgcatct cctgatcaaa atagtattgt ttcaaaaggc ccataaataa
     7681 atcttcatgc tcttgatccc caatgatgtc taactgattt tttatggcat ccggtagtgc
     7741 gggggctact gtctggctgt acgtaaaacg tagttgttca tcaattgatg caaatccgca
     7801 attttcaata attcctttga cattgacagg aatatctttc gctaatacag acatcatcgt
     7861 agctgctccc atcgaaccac cataaagtaa aatcttttga gatggccgct ctcgaacttc
     7921 ttgatttatc cagtaaagga cgtcatctga ctcatattgt ccataggtca cataatcgcc
     7981 tccgctatta ccagtcgctc tggaatcaac aaataataaa ttatacccgg ccttataaaa
     8041 atcattgtat tcttctgtaa cgatcccgtt attccaattc cctcgaaatc cgccatggat
     8101 catgactgtt ttatctgaac cttgatcgac ataatatgca tatacatcca tcattttgcc
     8161 atcttgtttg tttagtacag tttgatgaag ttgttttgta tttggataga agcctgtgtt
     8221 ttctgtaggc gttgtcccat catctgtacc tccaagcatc gacatcaaca cactgttttt
     8281 tgcaaaagcg atatcgtaca atagataagt agcaatcaga tgtttgataa tctctttatc
     8341 tacaccataa tcattaacag caagctcagt gactaataac tctattaatt ttgacttgat
     8401 gtcttctgtt ggtccattaa gtatttctgt catctgttta ccgaagtaat tcaaatattc
     8461 tttaccattg aaattttcac ctttaccgat atcatcattt tctgtcccat tctctttgtc
     8521 acttacttta gcagaagagg attcgtcgtt tgacattttt gtagctgttg cttcttctgt
     8581 ttgttggtta tctgtggtag cggtcgtttc ttgatctgtg ctagtaacag atgtctcaac
     8641 cgttgtttca gtatttgttt ctgtttgtga agtactcgat ttcgtttcat ttccagcatc
     8701 agtagtttct gtggtttcta cctcccgaga ttccgattcg gaagaaatgc tctctccata
     8761 tactgtccat tgcgggacgc ttgtacttac agcaaataag atgaccaacg ctccctttaa
     8821 tacttgtttt gttctcaagc tattcactcc tttttatgtt tctaggagaa ttatatgtaa
     8881 acgcaaacat tttttataca aaaaataaat ggtttatccc ataaaaatag aacaggatta
     8941 ttttctcatt ttacgtaata aagcagaatg gataaaccag tatccattct gcttttttta
     9001 aacgaagaaa caacttattg ctccaaaaat gtcagaaatc gtttatccca aattttctcg
     9061 taaaaagcga ttgtttcctt tgctttcata aaaggattat cataagttgt cgttgctcct
     9121 ctacacatca taagctggta tcctaatcca tgagcaaact tcacagtcgt atctatacaa
     9181 tactctgctt gtgccccaca taattcgatc gaatgacagt ccaattcagt taataaaaca
     9241 ctcaaattag tcttataaaa tgaattcgca tgggtttttc tcacaaaata actgtgctca
     9301 ggaatagata attccgacaa tagctcccat ggttttgttt gtggcactaa ttgagcatct
     9361 tcgtgttgaa cgaaaataac tggtttccca atcgtttcgt atgttttgat tcttttattc
     9421 actaatgctg tcactgtttc taattcgtgt atcggcgaag aatcaaaaca tacccctttt
     9481 tgtaaatcga tcactactat tgcgtcggct gtgtttgaca tacttgtgcc ttctttcttt
     9541 tttcttgatt taatagtatt tcttatctag ctagttccat tatacgtgac aacattttct
     9601 tattttacac ctctaaatgg cacttttcga ctatttcttc atgttattat ttcataaata
     9661 cttagctatt ggaggaatgt atgatgatta aattgtatac aggttctggc tgctcgtctt
     9721 caagacgcgc aaaacgttgg cttatcgtcc atgatatacc gtttatcgaa cagaacttaa
     9781 ttcgtcaacc actaaccaaa aatgaattta tccacttact aaaattgaca aacaacggcg
     9841 tgaccgaaat gctctctact cattctatta gttataaaaa tcttgttcac agaatagatg
     9901 aactcagttt gagtgaacta tatattgaga ttcgtacatc cccttcttta ttgaaaaaac
     9961 cgattatcta cgaccaatct gcaaaacttt tgactggatt tagcgaagat aaaatcagga
    10021 tgttcctttc taaaactaaa agaaagcaag agctcaacga actcttgctt tctggtcatc
    10081 ttgtcgattt taaagaaaat aatctttttg caatgtctta attttggcat aaacaatctg
    10141 cttttcttaa ttaacgaaat ccaatttttc caatatggat ctatttttct cattcctgat
    10201 ttttatgatt tcagctttca gacgcgccca atcatttttt gtaggttgtc cattccagta
    10261 aaatatctgt gtattcgttt gatcatatgc ctttttgtcg ataggataat cgctaatgac
    10321 aatatcaggt aactgatcag cggatgcact atattttatt gggcgttcag tcatagataa
    10381 tatccttttc tttgcccata attcctgtgt tttaccatac tttgattgaa tatagaatat
    10441 gacaggttgt tcgtgtttta taaaaatatc cctgactaac atacagtatt gaaaaatcaa
    10501 ccgtctgttc ttttcataat aagtattaag ctctggaatt ctgcgagcta ccccactaaa
    10561 aaactgttgc atgattggat acatcactgg aaatatatgc tgaaaatctc tgtcttctgc
    10621 tgattttcca aaagcatcca ccttcttttt tgtcccaaaa acccttgaat acaaatggat
    10681 cattgccaaa ttgacatata gataattttt ttctgaagtt gtaaaacaaa tcttgaagtt
    10741 tttttcaaaa ttttctacaa tagacgattc aatccagccc caactttctt gtactttatc
    10801 tggagtatcc aacaaatctt cttccaaata ggtgttcatt acaccaaaca taaaataaag
    10861 gtaagcttgc tctgttggag tgatgtgatt catcgaccag aagtttgctt caaaaaaagg
    10921 ctctagtatg taatgcgtaa actcttcttt tgttatcaat ggatgcacaa atttgttcat
    10981 ctcttctggg acatacgtaa tcgagtggcc ttgtttcatt cgttgcaacg aaattcttag
    11041 taggctgatc catttctttc tatctatact acgcgtatat ggcgcatgtt tcgcaaattt
    11101 ttctaatagt tgacgtttat tttttatact tgataatata tcagaatgat tttcgtcgaa
    11161 tgactgccaa tacatcaagt gaaaaaagta tcggatacgg tattcttctc cttctatcgg
    11221 attacctttt ttcaagctgc aagataaatg atagtttttc aaaatagtat taagttctct
    11281 taattttctt tgaatcgtac gcaaacttat ataatttttt gactaagatt ttctaaggat
    11341 tgataagtac ctttgtaaag tgaatccagt aaaatataac caatcgttcc ctctaaaagt
    11401 atagaataaa ctttactcag taaaaactga gaagaaaact cgacttttat catcttgttt
    11461 tctgaaagaa aagataattt atattctgga tacctttcgc aaaacgattc tgcttgttga
    11521 atcaccgaat tcatcttagc cagggtgtag tttagatcta aagcgatatc cttcaccaca
    11581 tataatttct cgtctctttc ataacaatag ttcaaaaatt gatatacttg cctttcattg
    11641 atatcaataa attcttcaaa caaagtacat actccttttt atctattatt tagacttatt
    11701 ccgacagcta catgaataac gtacaaatag attcgttact gatttttcag agatactacc
    11761 atgcgcagtg tgcattgtca attattcttg ctcttatttt ccatttgtgt tcctgttatt
    11821 tcctgtttct caaatatgtt agtaaacaaa aatagatctg gcaaagctac aacttcgcca
    11881 ggcaatacag cactctcgaa tgaaatattc actcaaaaat ctatcgtttt attcaatttt
    11941 agatctgttg cttttattct ttatttcact cgatggaaga gagaacgaaa atagcttgct
    12001 cctacaatca aaatgagtaa cacacccatc catgtaatta gcttgttcaa ggttctacta
    12061 ccagtttctg gtaaatcgct ttttctatta tctgtttctt tcgctttttc ttgatgatca
    12121 attccacgag aaacaaaatc aggctgtttt agcacacttt ttaggttgct ccctgcattt
    12181 ctcttttgtt ccttagttgg tatgataggt accaaatcaa gttcattatt tacttttcct
    12241 gtgctgcttt cgctgctcgt gcttcctgtg ctactctcac tactcatgct tcctgtgcta
    12301 ctttcactac tcgtactctc cgtactgctt tcgctgctcg tgcttcctgt gctactttca
    12361 ctactcgtac tctccgtact gctttcgctg ctcgtgtttt ctgtgctact ttcactgctc
    12421 gtactctctg tactgctttc accgctcgtg ttttctgtac tgctttcact acttgtgcta
    12481 tccgtactgc ttggcggtcc aacaactgtc caactgcttg gtttcaaatt ctccgtgatc
    12541 gtcatctgtc catcataaaa aacaatcaaa tcaactttat ctttactctt gatctcatca
    12601 atcgatagtt ctgcagaaat cattattgta tactcaatac cagcggtcca ttgtacgtct
    12661 tttaaataaa cttccccaat aactttttct gaacttccat taccatccca accatatgtt
    12721 agaacagcat gtacatcact agcattcacg cttttgtttg gtttgactgg aatagtaatg
    12781 acttgttgtg tcatgtcata aacaatccga tcagttttca cagtaaatga aagattctca
    12841 tttgcccgtt catttgcaga agtactgatt ccaatcattg ctgcaattat actcagccca
    12901 agaataacaa ataatacggt cgctgttttc ttcatttcta tcactctcca tataattacc
    12961 ttctatttga taaaggaatt atataaaatg aaaatgatga gaacacgaca gtcagttgtg
    13021 aaaatctaac aaaagatgtc gtgtattcgc ttgaatttgt ttactttttc gtttaatcaa
    13081 tgacagactt aaaaaagcaa gaccgatatc agccttgctt tcttcatctt ttattgataa
    13141 acagcagtgt atttcttcat ccgctttgtt ttatatgcat agagtaacaa accaacaatc
    13201 aagactaaca agaataatgt agttgatata gatgcttcag ccccaaagtt tcccccagta
    13261 attattgtat tttgcgattg gatcagagtg gagaaaaaac cttgttcttg cgttccgctg
    13321 actggtatac ccaaaatagc tccttgtgtc caattccaag taatatgagc accaatagcc
    13381 gtaaataaac ttcctgtact gtagataagt gcgctgaaaa agcaacctgc taaaaagata
    13441 ttgaaaactg ccagaaatgt catgttagga ttcaatccgt gcaaaagagc aaataatgca
    13501 gcagatccaa tcattgctat taacggacca aatctaagca tctgatgctg aaaaaagcca
    13561 cggaataaaa gctcttctga tgcccccact gcaataaata aaataaaact cgttatcagc
    13621 ggcacaatgt ttgcgtttcc tgaatctaac cgatacgccc ccgtcaaata taatggacta
    13681 gtaataagca gaaacactcc aattccaaca acgagacctc ccgctaaata cccccagtct
    13741 tttcctcgaa cagaaacacc ataatcttct attctttttc cttcgacctt actagcaaga
    13801 aataaagcta gtaaaaaaac agctaaatgt ccgaccgtac cggcaattgc tccaatccat
    13861 tcactatttc caataaacat atccgcaagt gcattattga caagaattcc taaaacaaaa
    13921 ccaactaaga ctattaaaac agatccaatc aaccgaataa tcctgatcat ctttcatccc
    13981 tcctttatat taagtttaac aacccttttc tttcttgtct cgtgaaaact atgtaaatgt
    14041 tctccatcat agagagaata gatttttacg aactaagaat atctacagca accttacgaa
    14101 aatgaaagac tgtctcccta attcttctgt tagactgttt ttaataagga aaggatggga
    14161 aattttttga aaaaacaact actaattatg tgcctttcag catgtgcaat tttactattc
    14221 tcaggttgta gcaagtccaa tgaaacgatt gcaacgttta aaggtggaac acttacagtt
    14281 caggattttt atgataaccc aaaagttaaa tcaaataatc aaacactatt aaaaaaaatg
    14341 attgtcttca aagcatttga tgatgtatac ggaaaagaga tttcttcaaa ggaagtaaca
    14401 aaagaatata atgaacaaat caaaaaactc ggtccaaact acaaggaaca attaaaagca
    14461 gttggccaaa cagaagagac atataagaaa ctctttaaac agatgctggc tttccaatac
    14521 ggtttgaaag ccaatgtaaa attaacagat aaagatctag acactgcttg gaaagaattc
    14581 tatccagaag ttagtacaca gatcattcta ttttcgacta aagaagaagc agataaagca
    14641 aaaaaagaag caaatgaagg agaaaatttc tccaagcttg ttcaagctta tggaaaaaat
    14701 aaaacattaa aggaaactga tggaaaaatg aattttgatt caaccaatcc agagattcct
    14761 actgaagtaa aaaaagcagc atttaaacta aaaaacgggg aagtttctga tatcattcct
    14821 gtaacagatc caacgactta tcagcaaagc tattatctag taaaaatggt aaaaaaacag
    14881 gataaaggtt ctaataaaga caaatacaaa tctgagctag aaaaaattgc taccgaagca
    14941 aaaactcttg atacggaatt catggataaa acaatccgta aagtgatgaa aaaagacaat
    15001 gtaactatta aagatcctta tgtaaaaaat atattcaaat aaacaaattt gacccaattg
    15061 gggatgtggc aaaatttgag aagtgatttt tggaaattcc ttcttatttt tgaggcaaac
    15121 cacttttgcc acaacttcat cggggccttt ttttatttgt accaaaacaa atcactggat
    15181 ttgttacaat catgaggata taatttaaaa aagtttttta tttctatcac atgaatcaat
    15241 gcgccattaa gtagattctt tcatgcttcc ctattttttc acttgccgta tcgcttcaaa
    15301 aacaactatc ataaactcaa actcgactga aaagttattt taaaaaagac taaaaatatc
    15361 ccttctggac ttgttcttct tattctgtta tactagagaa acacgaaaga tatttttatg
    15421 cgacactttt catttgtttt tatgaaattt attcaaaact ggcgtaactt cagagttaca
    15481 aggatgtatt agaggttagg gaatacatcg tttaaatgag aaataagtaa tagttagtaa
    15541 tagtcaccca aactttaaat taatgaatat tgaatcgtca gatagcctcc tcgagttttc
    15601 gagaaggcta tcgtttattt tatggagaaa ttgattcaga agtaatcagc gacctttttt
    15661 agttcaccaa tcgtttctgc ttggaaagtt tgcacccaat cttcttggaa gcccctcact
    15721 gctttatcaa tcgagggcat ctctaatact tgatctagta gctctttacc taacgttatc
    15781 gcatgagctc cagatcgaat ggctgtagtg acttgttcac aatttttgaa actagctgct
    15841 aatatttttg ttggtctttg cgtacgttcg atctcagtcc gcaacgaatc aatcactttc
    15901 atagcatcaa tgccttgatt ttgcatcctg ttataataag gtgcaatata atctgctcca
    15961 ttattaatag ctaaataccc ttgtaattct gtgtaaatag ctgtaccggt aatcaaataa
    16021 ccttcttttt tcaacttttt gatcgcttga aggcctgctt gattcaccgg caccttgata
    16081 aacgtatctt ttcccagttc ttctatgata actcgagcat cctctatcat ttcttcttcc
    16141 gttcttccta ttgtctgaat atggatagga atctgtccga ttattttttt gatttctttc
    16201 atatgcgaga agaagtttga cgctccttct tttttcagaa ttgtaggatt tgttgttacg
    16261 cctgttaaat tcaaaaactg ttgacaagaa taaatacttt ttgtatttgc tgtatcaagc
    16321 atgatttcca tatagctttc ccccattctg atcctcttga tcgattttaa tgattgtccc
    16381 ctttcttaaa tgcggcattt ccttatcttc tacatacatt gttcctggaa gttccggctc
    16441 atgagatcca tcaaatttta tcgtgatatg tcctaattca ttcaaattag tttggacaac
    16501 atctcctact gctgtgatta catacatttg tttatcaaaa cagagcttca tatcacaagt
    16561 tatttctttt cttacctgat tcaattcaat cttataacaa taatctgtta atgtttccgg
    16621 tgcttcatct ccaaataaaa tcattatttt ttctttcctg aatacttctg cttctatacc
    16681 aacatctgtt acaaccgttt caaagatcgt catctctgtt cctcctcgta aaatatcatt
    16741 tgtctaatag tttttattca aaatgtttct agattataaa atttattgaa taacacattc
    16801 ctaacggaat ttgtttcgat attgtgtgat ttctcagagt acaatggatg tatgga
//
LOCUS       DAIGQM010000063        16615 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.065, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000063 DAIGQM010000000
VERSION     DAIGQM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.065"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="NOA48_002135"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="NOA48_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI0790378.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="NOA48_002136"
     CDS             complement(680..1666)
                     /locus_tag="NOA48_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0790379.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="NOA48_002137"
     CDS             complement(1689..2255)
                     /locus_tag="NOA48_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCI0790380.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="NOA48_002138"
     CDS             complement(2269..2685)
                     /locus_tag="NOA48_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0790381.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="NOA48_002139"
     CDS             complement(3142..5076)
                     /locus_tag="NOA48_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0790382.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="NOA48_002140"
     CDS             5357..6313
                     /locus_tag="NOA48_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCI0790383.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="NOA48_002141"
     CDS             6403..7506
                     /locus_tag="NOA48_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCI0790384.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="NOA48_002142"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="NOA48_002142"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCI0790385.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="NOA48_002143"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="NOA48_002143"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCI0790386.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="NOA48_002144"
     CDS             complement(10887..12140)
                     /locus_tag="NOA48_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0790387.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="NOA48_002145"
     CDS             complement(12146..13069)
                     /locus_tag="NOA48_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0790388.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="NOA48_002146"
     CDS             complement(13290..15782)
                     /locus_tag="NOA48_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI0790389.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="NOA48_002147"
     CDS             complement(15789..16256)
                     /locus_tag="NOA48_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCI0790390.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="NOA48_002148"
     tRNA            complement(16392..16465)
                     /locus_tag="NOA48_002148"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="NOA48_002149"
     tRNA            complement(16523..16596)
                     /locus_tag="NOA48_002149"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4907 a         3476 c         2957 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAIGQM010000064        15860 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.066, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000064 DAIGQM010000000
VERSION     DAIGQM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.066"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(12..482)
                     /locus_tag="NOA48_002150"
     CDS             complement(12..482)
                     /locus_tag="NOA48_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCI0790391.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="NOA48_002151"
     CDS             complement(641..1099)
                     /locus_tag="NOA48_002151"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCI0790392.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="NOA48_002152"
     CDS             complement(1270..2415)
                     /locus_tag="NOA48_002152"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCI0790393.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="NOA48_002153"
     CDS             complement(2428..3345)
                     /locus_tag="NOA48_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCI0790394.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="NOA48_002154"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="NOA48_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCI0790395.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="NOA48_002155"
     CDS             4437..4607
                     /locus_tag="NOA48_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790396.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="NOA48_002156"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="NOA48_002156"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCI0790397.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="NOA48_002157"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="NOA48_002157"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCI0790398.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /locus_tag="NOA48_002158"
     CDS             6871..7752
                     /locus_tag="NOA48_002158"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCI0790399.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /locus_tag="NOA48_002159"
     CDS             7749..8465
                     /locus_tag="NOA48_002159"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCI0790400.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="NOA48_002160"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="NOA48_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCI0790401.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="NOA48_002161"
     CDS             9182..10183
                     /locus_tag="NOA48_002161"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCI0790402.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="NOA48_002162"
     CDS             10180..11541
                     /locus_tag="NOA48_002162"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCI0790403.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYGTVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="NOA48_002163"
     CDS             11501..12652
                     /locus_tag="NOA48_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCI0790404.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="NOA48_002164"
     CDS             12627..13796
                     /locus_tag="NOA48_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0790405.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="NOA48_002165"
     CDS             13971..15350
                     /locus_tag="NOA48_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0790406.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="NOA48_002166"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="NOA48_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5184 a         2799 c         3379 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgga
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DAIGQM010000065        15135 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.067, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000065 DAIGQM010000000
VERSION     DAIGQM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.067"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..1198
                     /locus_tag="NOA48_002167"
     CDS             <1..1198
                     /locus_tag="NOA48_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0790407.1"
                     /translation="IASNIRAIYVDEFQDTRELQYNVIAKLLQNNPQIQSMFVGDIDQ
                     AIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCYRSNQRLVDFYSNFQSCPYEIESRGN
                     NKNDRGFISYDCKVTKEDLPNIIKNIIKEKIESGIHEKDICVLAPQHYPLFSLGEYLK
                     KELPYCNFDAINISPIKVNNHSLFFKLAILYFTESGEKVRRRKLIANDILIILKNEFG
                     IEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLNIDEKNYPSIFKHY
                     LFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNEYDTVIAINLLNGK
                     IPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLLYPTQLLDKI
                     EFDYNI"
     gene            1398..1712
                     /locus_tag="NOA48_002168"
     CDS             1398..1712
                     /locus_tag="NOA48_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0790408.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1733..2110
                     /locus_tag="NOA48_002169"
     CDS             1733..2110
                     /locus_tag="NOA48_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0790409.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            2120..2893
                     /locus_tag="NOA48_002170"
     CDS             2120..2893
                     /locus_tag="NOA48_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790410.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2915..4318
                     /locus_tag="NOA48_002171"
     CDS             2915..4318
                     /locus_tag="NOA48_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0790411.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            4500..5684
                     /locus_tag="NOA48_002172"
     CDS             4500..5684
                     /locus_tag="NOA48_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0790412.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5681..5971
                     /locus_tag="NOA48_002173"
     CDS             5681..5971
                     /locus_tag="NOA48_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790413.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5968..6189
                     /locus_tag="NOA48_002174"
     CDS             5968..6189
                     /locus_tag="NOA48_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790414.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            6231..7010
                     /locus_tag="NOA48_002175"
     CDS             6231..7010
                     /locus_tag="NOA48_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCI0790415.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            7077..7571
                     /locus_tag="NOA48_002176"
     CDS             7077..7571
                     /locus_tag="NOA48_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0790416.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            7627..8265
                     /locus_tag="NOA48_002177"
     CDS             7627..8265
                     /locus_tag="NOA48_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790417.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            8337..8732
                     /locus_tag="NOA48_002178"
     CDS             8337..8732
                     /locus_tag="NOA48_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0790418.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8716..11169
                     /locus_tag="NOA48_002179"
     CDS             8716..11169
                     /locus_tag="NOA48_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0790419.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            11166..13193
                     /locus_tag="NOA48_002180"
     CDS             11166..13193
                     /locus_tag="NOA48_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790420.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            13190..14212
                     /locus_tag="NOA48_002181"
     CDS             13190..14212
                     /locus_tag="NOA48_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI0790421.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            14229..>15135
                     /locus_tag="NOA48_002182"
     CDS             14229..>15135
                     /locus_tag="NOA48_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0790422.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQ"
BASE COUNT         5163 a         2520 c         2987 g         4465 t
ORIGIN      
        1 tattgctagt aatataaggg cgatttatgt ggatgaattt caagatacta gagaattaca
       61 atacaatgta atagctaaat tacttcaaaa caaccctcaa attcagtcaa tgtttgttgg
      121 agatattgac caagcaattt atggatcatt agatggtata gctaaatcag ttgaagaact
      181 agaaatgcta actagtcaca cttttcaatc aaagacgcta catggctgtt acaggtctaa
      241 tcagagatta gtagacttct actctaattt tcagagttgt ccttacgaga ttgaaagcag
      301 agggaataat aaaaacgacc gtggttttat aagttatgat tgcaaagtta ctaaggagga
      361 tttacccaac ataataaaaa atataataaa ggaaaagatt gaaagcggca ttcatgaaaa
      421 agatatttgt gtacttgctc ctcaacacta tcctctgttt tcactgggtg agtatttaaa
      481 gaaagaatta ccgtattgca attttgatgc tataaatata tcaccaatta aggtaaataa
      541 tcatagttta tttttcaagt tagcaatttt gtactttact gaatcaggtg aaaaggttcg
      601 aagaagaaag ctaattgcaa acgatatttt aattatatta aaaaatgaat ttggaataga
      661 agttaaagat tattttattg acttagattt attacagcta ataaacagtg tgaaaagaat
      721 gtatagtgga gacgacaacg gtgttgattt atacaaattt gttaccaaac atatatttgt
      781 taatcttaat attgacgaga aaaattaccc gtctattttt aagcactatc tattttttat
      841 taacgaagta gaagatcgga taaaaaataa ttcattatct agtagtgtat ctagttttaa
      901 gaagatgttt aaatctcgag atggtatcac acttactaca gcacataaag ttaaaggaaa
      961 tgagtatgat actgttatcg ctattaatct tctaaacggg aaaattcctc attggaatga
     1021 aatttttaat gtttctgata aaggaattag ttcagcgaga aaactactat acgtaatttg
     1081 ttcaagagca aaaaataatt tatttctttt ctcagaggtg ggttatttta cgagtaaagg
     1141 agacttgctt tatcccactc aattattaga taaaatagaa tttgattata atatttaaaa
     1201 tacctaggta gtcgttgttt taaatatagt aggaatcgga cgctcagtac ggagcgtcta
     1261 tttttttacc caattttgaa aggaagtgaa cttatgaaaa taaaaaatca agaatcaaaa
     1321 ggtcgctctc ccccctttaa aaccatcaca caaataagat tcattcaaac ataaaaacag
     1381 aaaggatagg taaaaatatg gaacttaaat atgtcattcc caatatggaa aaaacatttg
     1441 gacaattaga atatgctggt gaagggaaca ttgaacaacg tcgaataaat ggcagaccaa
     1501 ccattctctc tcgtagttac aatttatact caacgattca acgagcagat gatattgttg
     1561 tcattcttcc ctccgaagct ggcgagaaac attttgaatc cgacgaaaaa gtcaaactca
     1621 tcaacccaca tattaccgca gaaggttata aaattggcaa tcgaggattt accaattaca
     1681 ttatgcacgc agacgatatg gtgaaagcat aagaaaggaa aggtgaaaaa atatgagatt
     1741 agcagaaggt attgtgattg aaaaagacca gacatttggc acattgaaat tttccgcctt
     1801 gcgtcgtgag gttcgtatcc agaatgaaga tggtacggtt tccgaagaaa ttaaagaacg
     1861 tacctatgac ttaaaatcaa aaggacaagg acgcatgata caagtcagta tccccgcttc
     1921 tgttcctttg aaagaatttg actacaacgc agaagtggaa ttaatcaatc ctgtggcaga
     1981 taccgtagcg acggctactt ttcgaggggc agacgttgat tggtacgtga aagcagacga
     2041 tcttgtatta aaaggacaga caaaacctca tcagaaatat aaaaaagaag cgtccgaaag
     2101 tgaaaaatag gtgttgctta tgacaaacac accattgatt ttgaaagaaa ttccgaagga
     2161 tgaagccatt tcttttattc ggcaatacca ttattcaaag atactcccta gattgtgtaa
     2221 atactttcta gggatttttt cagaagaaaa attattaggc gttgtggaat taggctgggg
     2281 tacgcaaccc ctacaaacca tacgcaaact ctttcccgac agttcccttc aaaccacaga
     2341 ttatttagaa attggaaaga tgtgttttct tccagaaatg aatcaaacca attattttgg
     2401 cagtcaagct ctttcagctc taattaagtg gttgaaagaa catacggact gtcatttttt
     2461 atatacactg gcagatggaa ttgagggaaa atgtggctat gtctatcaag cgtccaactt
     2521 cttttactgc gggtatttca agacaagtgt ctatcgtgat aagcagtcat gggaaaagat
     2581 acaccctcga agtgctcgcc ttttattaga ggaaaatgct cgctttgaac aggtagagaa
     2641 aaagcattgg ctttcccagg cattttgcga atacaaaggg attgagaaaa tcaatggacg
     2701 catgtttcgc tatctctatc cgttgacaaa agaagcgaaa aaactgttag gacacactct
     2761 ctatcgacgt cattattatc cgaaagaaaa aaatttacgc tttgaaaagc gaatcgctta
     2821 tcagaaatat gaagccattt ctcaaccaac ttttgataaa caggctcgta tctacaatac
     2881 acaattattt tgataggtgg aaaggaggat ttttatgcca ttgcttcatg acagaggaga
     2941 gcgaatcaaa gccaacgata agcacttggt ctatcatttt gtactaattt cattgctggt
     3001 agtttttcta gtcgtcctac tcccttttca ttggagagcg ttacaatcgg tgaactggca
     3061 agcagttcag ttagatacat ttttctatca acttcatacg ccatactttt ggagcagtat
     3121 tctcactgct ctttttgtat gcggacttat cagctggctt tattatcact atcgtataga
     3181 ttctataaaa cagttagagc accgtcaaaa gttagctcgt atgattttag aaaatcattg
     3241 gtatgaagcc gaagaaactc aatcagaggg attctttaaa gatttaccca gcaagaaaac
     3301 caaacaacga atccgccatt ttcctaaaat atattatcga atgaaagatg gactaatcca
     3361 tattcatgta gaaatcacct tagggaaata tcaagatcag cttttgcacc tagaaaacaa
     3421 actagaaaca ggattgtatt gtgaattagt ggaaaaaacg ttgaaagatt cttatgtaga
     3481 gtatgtccta ctttatgata ctattggcaa tcgaattggc attgaagacg tggtagctca
     3541 agatggacgt gtcaaattga tggaatcggt ctattgggag ttcgattctc tccctcacat
     3601 gttaattgct gggggcactg gtagtggaaa atcctatttt attctcacat tgattgaatc
     3661 tctcctgcat acaaatgcaa agctttatat tcttgaccct aaaaatgctg atttggcaga
     3721 cttaggggcg gtcatgaata atgtctatta ccgtaaagaa gatatgttgg catgtatcaa
     3781 tcaattttac gaagatatga ttgatcgcag tgaaaccatg aaacaacacc ctaactataa
     3841 aacaggagaa aattatgctt atcttggttt gtctgccaat tttcttattt ttgatgaata
     3901 tgtggcaatg atggatatgc taggtcgtga aagtaccacc gttattcata aactcaaaca
     3961 aattgtaatg ttaggacgac aagcaggctt ctttttaatt cttgcctgtc aacgtccaga
     4021 cgcaaaatat tttagtgatg ggattcggga caactttaac ttccgtgtgg ctttgggtcg
     4081 tatgtctgaa atgggctttg gtatgatgtt cggaagcgat acacaaaaac aatttttctt
     4141 aaaacccatc aagggaagag gttacgtgga tacaggaaaa agtgtgatta gtgagtttta
     4201 tacacccctt gtaccaaaaa ggtacgattt cttaggagaa ataggaaaag tcattcaaaa
     4261 aaagcaatct gagcctgtac cgcacgaagt gaaaggtaca ggttcagact tgctttgatt
     4321 ggtgtggcgt tagccacgcc aatcctttag ccccctctat ctaacagggg ggcacaaata
     4381 caactgaaaa caggcaattc tcatcaacca atgttgatgg tacaaaggat tgcggaaaat
     4441 atgaaaggtg taaactcaag ggtcatagtt tacatctttt ttagattgga ggtttgcgaa
     4501 tggaaaacga aaaaatttgg attaaggaat tgaaagaaaa gcgactggct tatggcgttt
     4561 ctcaaaataa actggcggtt gcttctcata ttaccagacc ttacctatcg gatattgaaa
     4621 caggcaaggc agtccctact caacaggtga aagaagattt actgaacgct ttggaacgct
     4681 tcaatcccga taacccattg gagatgttat tcgactatgt acggattcga ttccctacca
     4741 atgatgtggc tcaaattatc ggtgaggttt tacgtttgaa tatggattat atgctacacg
     4801 aagactttgg ctattattct tatcccgaac actatcgttt cggtgatatt gttgtcctag
     4861 tctctcatga tgtaagtaaa ggtgttttat tagaactgaa aggaaaaggc tgtcggcaat
     4921 ttgaaaactt tctattggct caacatcgga gctggtatga tttctttcaa gattgcatgg
     4981 aacataaagg tattttcaaa cgcttggatt tagctatcaa cgataaaaca gggattttga
     5041 atattccaga tttggcaaag aaatgtaaac aggaagaatg catttccgtc tttcgaagct
     5101 ttaaaaatta tcgcagtggt gaattggttc accgtgatga aaaaccatac atgggaaaca
     5161 cactttatat tggctcatta aaaagtgaag tctatttctg tatatatgag aaagattatg
     5221 agcaatacgt gaaaaatgat gttcccttag aagacgcaga agtaaagaat cggtttgaaa
     5281 ttcggttaaa aaatgaccga gccacccaag ccatgaaaga tttattggca catcaacagg
     5341 cggaaaaaac agcctttgaa attatcaatc gctatatccg ctttgcagat aaagacgaca
     5401 ctaaacgtcg gagtgattgg aaaactaatg aacgttggga atggtttatc ggtaaaaatc
     5461 gtggagcatt acgcctaacc acacagccag agccttattc ttttgaacga acattgaact
     5521 ggttacatca tcaagtcgcc cctacattaa aaatcgcaag cattttagat gttctcaacg
     5581 gtacaaccat tatctccacc atgattcagg aagccaaact gacagaaaaa catgagaaat
     5641 taattgaaca acaacatcta gccatggagg atttgattac atgagccttt taacaaaaga
     5701 attaaagaag ttagggtttc agtgtggcat tgagtttcaa gcgtatatac aaaatacagg
     5761 gaaatatacg tctctcatta ttgagggaaa acggcaagct ggtgatacca tctataccta
     5821 tgatttttac aaggtgagat tttataataa ttataccaat cgagtaaccg tctatggaga
     5881 gcatttaacc ccttttcaat tattaaggcg tgtaaaaagc tatatctatt atcgagaaaa
     5941 atatcttaag gaaaggagga caatcacatg aattttgggc agaatttgta caactggttc
     6001 ttggataatg cacagtcatt ggtattgtta gcgattgttg tcattggact gtttttaggt
     6061 tttaaacgag aattttcaaa actcattggc ttcttgatta ttgctctaat cgccgtcgga
     6121 cttgtgttca atgcagctgg cgtgaaagat gtgttattaa acttatttaa ccgaatcatt
     6181 ggtgcttaac agatattttt catgataaaa taggaagtat atattttgtt atgaaaggat
     6241 ttatgaatat gtttacaaat gatcaattta aatctctttt aattaaaaca ttagaaagaa
     6301 agagctcttc aaattattat gaaggaggta acgagattgt ttctaaaatg aaaatatcag
     6361 aggtaacttt agatgagact gacgatttta cttattataa aggatataaa aagggctgga
     6421 atacgctttg cacatatctt aaaataagag ttccttttga tgatttagac ttttttgaaa
     6481 gtcataaaga tttgattacc cagacagcaa gctccatata tgataaacaa ggtgataatg
     6541 tattagtgga tactatttta gtaccacttc cagagaatta cgaagtaatt aactttagtc
     6601 agttgaaaat tagtgatgtg gtttcacaag ctattgaaga cgctgagtct tttatgagta
     6661 atggtgaata tcaacgtgcc tttgacagag ttcacactgc ttttcatgga tatttaattg
     6721 aaatactaaa aaaatatgaa attacagttc ctagagacga aaatctatct aaattatata
     6781 gtaggataca acaattaatt gaaaaagaaa ttcaacctac tgaacttgct gatatagtga
     6841 agacaacgat aaggtcatca aatggaatga ttagctctct taatgaagca agaaataggc
     6901 attcacttgc acaccctaat acaaatatta ttggaaagag agaagcaaaa ctaataatag
     6961 gtatttcaag tacagttaca gattatatta gcggatacct tgataagtag cgtcattaac
     7021 tgattgctac tttttttatg actattttta taaaaaggat gtgataagaa ttggaaatga
     7081 aagtctatgt ggcaaattta ggacggtata atgaaggtga attagtcgga gcatggttta
     7141 ctccaccaat tgatgaggaa gaaatggcag aaagaatcgg tttaaatgag gactacgaag
     7201 aatatgcaat acatgatttt gagcttcctt ttgatgtgga cgaatacacg ccgattagtg
     7261 aaatcaaccg tctatgtgaa gccattcaag aaatcgaagg tacacctatt tataatgaac
     7321 tcaaagaaat tcaaggcatg tggtttagta gcttggaaga attactggaa aacaaagagg
     7381 atattcattg ttatagtgat tgtgattcga tggaagatgt cgcccgttat tacgtggaag
     7441 aaacaggaca gcttggtgaa gtcccttcca atttacaaaa ttatattgac taccaatctt
     7501 tgggacgtga tatggaaata gagggtaatt acctagttac ctctcatggg gtatttgaat
     7561 attgtcagta agtttaacaa tccgtgttat aattaaatta ataaatagca cggagaggta
     7621 taaattatgg taaatgtatt tgaaaatctt aaactattaa aactagacat gaaagataaa
     7681 ggctgggtga tagattcctt ttactttcgt tacaaacagc aaaattatat tgtacttgtt
     7741 aagctatttg aaaaagagga aaaagttcca gaatatgctc tgttaaaact agaattttta
     7801 aaggaaaacg atttttcaga tatgctagct gtctatgcta attcggtaaa attatataca
     7861 gacacgaaaa caataagaga atattttggt atcgaataca gtagtaactt gggagatgtt
     7921 ttatttcaat ttagccaaac tcttgctcga tttattccga cagaagttag tgagaagaaa
     7981 aatgaagacc aaaaagaagc catgtgtttc tcattaagtc aaagtgattc agaagatccc
     8041 agaaaaaaat attgtttttc agttagaaga aatcctttaa agggaaatgg tgagctggga
     8101 aaacgaagtc cttttaatga caataaaacg agattgtata gacccagctt atatgaacga
     8161 ttagggtcag ataccaattt aagtttcaga tattcaatga atccagatga tgaagaaact
     8221 gatgaaggta ttattgcaaa atggacaaaa aataaaattg aatagttaaa gcattgaaag
     8281 agcaatcacc tattttgatt gttctttttc tatttttacg gaaaggacgt gaagacatga
     8341 aaaaaataag aagttacacc agtatttggt cagtagaaaa agtgatttat gcgattaatg
     8401 atttacaact ccctttccca attaccttta cgcaaatgac atggtttatc gtttctttgt
     8461 ttgtcgtcat actctttggc agtttaccac cactttctct gattgacgga gcactactca
     8521 aatacttagg gattcccatt gttctcactg ggttcatgtg ccaaaagacc tttgacggaa
     8581 agaaacccta tggatttcta aagtctatca ttacctatgc tctacgccct aaagtaacct
     8641 acgctggcaa acaaatacga ttaaaaaaag aaacaatgaa tgaatcgatt acgattgtaa
     8701 ggagtgaaca actagatggc atatccgatt aaatatatgg aagataatct cgtatttaat
     8761 catgatggcg aagtattcgc ttattatgaa ttaattccct ataattacag ttttttaagt
     8821 tccgatgaaa aaattcaagt tcatgataat ttctgtcaat tgattgccca aaatcgtgat
     8881 ggcaagattc atgctctgca actagcaacc gaatcaagta ttcgagccac acaggaacaa
     8941 tcgaaaaaag aaatcactgg acgattaaaa gagatagctt acgaaaaaat agatgaacag
     9001 accgaagcgt taatttctat gattggtgac aatcaagtag actatcgctt ttttattggt
     9061 tttaaactct acctcaatga acaggaagta tccgtaaaaa atgttgggaa agaaattcaa
     9121 aaagcatttg cggaattctt tcatggtgtg aatcacaaat taatgggcga ttttgtttct
     9181 atgcctatgg cggaaatcga acgcttttct aagatggaac agttgttaga aagtaaatta
     9241 tccagacgct ttcagattcg taaattggag aaagatgatt ttggttatat tattgaacat
     9301 ctttacgggc aaacaggtgt cccttttgat gactacgact accatttacc gaaacgatac
     9361 gaagataaaa aagtgttggt aaagaaatac gatattctca aacccactcg ctgtttaatc
     9421 gaagaaaatc aacgctattt acggattgaa caggaagata ccactactta tgtggcgtat
     9481 tttacaatta atagtattgt tggtgaattg gatttcccta atagtgaaat tttttattac
     9541 cagcaacagc agtttacttt ccccgttgat accagtatga atgttgaaat tgtcgccaat
     9601 aaaaaagcct tatctaccgt tcgcaataaa aagaaagaac tgaaagattt agatagccac
     9661 gcatgggaaa gcgacaacga aaccagtact aatgtggtgg acgctttaga atctgtcgat
     9721 gaattagaaa gtaatttaga ccaaaccaaa gaatctatgt acaaactaag ctatgtggta
     9781 cgggtatcag caaagaattt ggacgagctg aaacaacgtt gtgatgaagt aaaagatttt
     9841 tatgatgatc tgtctatcaa attagtacga ccttttggcg atatgctagg cttgcataat
     9901 gaatttattc cctcaagcaa gcgatatatc aatgactata ttcaatatgt cacgtcggat
     9961 tttttggctg gtcttggttt cggtgctaca caaatgattg gtgaaaattc tggtatttac
    10021 gtcggttaca atctcgatac aggcagaaat atttatctcc aacctagcct tgcaagtcaa
    10081 ggaattaaag gctctgtaac aaatgcatta gcgtccgctt ttattggttc attaggtggc
    10141 ggaaaatcat tctctaacaa tatgctggtc tattattcag tactctttgg cggacaggca
    10201 accattgttg acccaaaagc tgaacgtggt gaatggaaag aaaccttacc tgatattgcc
    10261 catgaaatca atattgttaa tctcacgagt gagaacgaca ataaagggtt acttgaccct
    10321 tatgtgattt taaaactccc gaaagattca gaaagccttg ccattgatat tctcacgttc
    10381 ttaacaggta tttccagccg agatagcgag aagtttcctg tcctgcgtaa agctattcgg
    10441 agtgtaactc aaagcaaaca acgagggttg ttattggtga ttgatgaatt gcgaaaagaa
    10501 gatacgccca tcagcaatag tattgctgac catatcgaaa gctttgtcga ttatgatttt
    10561 gcccatctgt tattcagtga tggcagtgtc acccaatcca ttagcttgga aaaacaactc
    10621 aatattattc aagtggcaga tttggtctta cccgattcca atagctcttt tgaagaatac
    10681 actaccatgg aattattaag tgtggcaatg ctgattgtca ttagtacctt tgctttagac
    10741 tttatccact ctgaccgttc catttttaaa attgttgacc ttgatgaggc ttggagtttt
    10801 ttacaagtgg cacaaggaaa agctctatct atgcgattgg ttcgagcagg acgtgccatg
    10861 aatgcagggg tctatttcgt tactcaaaac gcggacgatt tactagatga aaagatgaag
    10921 aataatattg gcttgaaatt tgcctttcgt tccactgacc tagtggaaat caaaaagacc
    10981 ttagaatttt ttggtgtgga caaggaagat gaaaacaatc agaaacgctt acgtgaatta
    11041 gaaaatggac aatgtttagt ttcagacatc tatggtcgtg taggggttat gcagtttcac
    11101 ccgatttttg aagagttgct tcatgccttt gataccagac cgcctgtgcg aaatgaggtg
    11161 gaagaatgac acaaaaacaa aagaaatttc ttcactatag ttggataacg ctcctttgtg
    11221 tgggcgttat tttactttta ttaggcacgc tgggcaatgc agtacaagcg acaggcttag
    11281 ttgatgaaac cattgataca agcaatgaat actccaagta tggtttgaat caatatcagc
    11341 ttgattatta tgtggacaat agctggggct ggcttccatg gaattggagt gatggcatag
    11401 gacaatcggt gatgtatgga ttgtatgcca ttactaattt tatttggaca atttctcttt
    11461 atctatcgaa cgccacaggt tatttggtga aagaagccta tgccttagat ttcattagtc
    11521 aaacatccca agcaattggc gaaaacatgc agacgattgc aggcattaca ccgaatggct
    11581 tttccagttc agggttttat gtcggtttcc tccttctttt tattctcatt gttggaatct
    11641 atgttgccta tacaggattg gttaagcgag aaacgacgaa agtgatacga gctgttttaa
    11701 actttgtcgt ggtgtttatt ctatcggctt cctttattgc gtatgcaccc gattatattg
    11761 cgaaaatcaa tgatttttcc aaagatgtca gtaccgccag tctgaatatt gggacaaaaa
    11821 ttgttcttcc taacacggat agtcaaggga aagacagtgt ggacatgata cgtgacagct
    11881 tattctctgt tcaagtaaag caaccatggc tattgcttca atatggctcc actgatgtag
    11941 aagcgttagg ggaagaacgt gtggaaagtt tattgtctac cagtccagat acaaacaatg
    12001 gtgaagatag agaaaatgta gtgattgaag aaattgaaga tcatgacaat acctatttaa
    12061 ccctaccgaa gacgatttcc agattaggaa cagtcttctt tttgtttgta ttcaatattg
    12121 gtatctcgat ttttgttttc cttctaacag gaatcatgat tttttcgcaa gtgctattta
    12181 ttattttcgc tatgtttttg ccaatcagtt tcctattaag tatgttgccg agttttgatg
    12241 gcatgggcag gcatgccatt accaagttat ttaatgtgat tatgacaagg gctggtatta
    12301 ccttgattat taccgttgcc tttagtattt ccactatgct ttattcgctg tcagcaagtt
    12361 ctcccttttt catgattatg tttttacaaa ttgtgacctt tgcagggatt tattttaaac
    12421 tgggcgattt aatgagccta ttcactttac aaagcaacga ctctcaaaac atgggcagac
    12481 aagtgtttcg cagacctcgt caaatgatga atcgacaaac cagaagattt caacgcagta
    12541 tgagtaagat ttttcgtgga aaagcagggt caacgaagca aaagacaatg acaacaaagc
    12601 agaatcaaac caataaagct aaccatactc gtcaaaatga acggactaca ccaaagaaag
    12661 aaacagcact ttccaatgtg aaaaagcaac aaggcggtat cgggcaacga ttaggtgaaa
    12721 agacagccca tgtattggac acgaaaaatc gtctagtcaa taaaagaaag caggcaaaac
    12781 aacagataca ggcgacacca acccatgtca aatatgccct tcatcaagga aaagagaatg
    12841 tcactcataa tgtaacagac tttaaacaat ctatggcaga taccaaagct caacgcaaac
    12901 aacagcgtat gaaccagcag gagcaaaaac gaaagaacat tgctcaaaag cgtttggagc
    12961 tggataaagc aaaagaaaaa agacgaaaag aaaacccatc atctcctgtt cagaataacc
    13021 agcagcatgt tcgcaagcgt cagcaaaccg tcacgcctgt tttgtcacaa aacactaaac
    13081 gtgaaaatca tcagcgacca ttgaaaaaag agcaaaaaca aaagacacca ccgaagcaat
    13141 tcaatcagag gaagctaaat aaaagaacgg ataagcgagg acaacaaaca tgaagctaaa
    13201 aataacagtg atttgtagtg tggtcttctc tctcttcttt tttctcttat tattcctagt
    13261 cattttcttt gcagatgata cggacagtgg cgaaaacaac aaggattctt ctattccaca
    13321 aggcggtgtg accgtttcac cagaagtgtt ggcacaccgt ccgttgattg aaaaatatgg
    13381 taaggaatat gggattgaag actatgtttc ttatatctta gccattatgc aagtggaatc
    13441 gggcggtaca gcagaagatg ttatgcaaag ttccgaatct ttgggtttac cgcccaacag
    13501 tttgagtacc gaagagtcca tcaaacaagg ggttaaatat ttcagtgaat tattaaccag
    13561 tgcagaacaa caaggagtgg atatagattc tgttatccaa tcttataatt atggcggtgg
    13621 ctttttaaat tatgtgagga gtcatgggaa aaaatatacc tatgaattag ccgaacagtt
    13681 ttctaaagag aagtcgggtg gtcaaaaagc agactatccc aatcctatag ccatacctgt
    13741 gaatggtggt tggcgatata actatggaaa tcagttttat gttcagttgg tttcacaata
    13801 cctaaccgac acttccccaa cagaatttga tgatgaaacc gtgcaagtca ttatggacga
    13861 agccttgaaa tacgaagggt ttccctatgt ctttggaggg gcgtcgccta ccacctcttt
    13921 tgattgtagt ggcttaatac aatgggtgta tgacaaagct ggcatttctc tccctcgtgt
    13981 cgcccaagat cagtatgacg ctacgcaaga aatctctatg gaagaagccc aagcaggcga
    14041 ccttatcttc tttcattcaa cctataatgc aggcacatat gtgactcatg tggcgatata
    14101 tttagaggga aatcgctttt atcatgcagg cgacccaatc ggttatggcg acttaagcag
    14161 tcgttattgg caagaccatc tgattggggc tagacgtgtt attcataact aagaaaggaa
    14221 tgaatcaaat gattataaaa atcgagcgaa aagaaaagaa ggagaaacca aagaaatcta
    14281 aaaaaccgag caagcaaaga aaagttccga tgattaaagt tggcacgcat aagaaattaa
    14341 cctttgtttt atgggtttta ttgattggta gtgtcggatt tggaatctat aaaaatttta
    14401 ctgccattga cactcatact gtccgtgaaa cagaaatcat taaacagcag attgtcgata
    14461 ccaaccaagt agaaagtttt gtgaaatcct ttgcgaaaga ctacttttcg tggcaacaat
    14521 cccaagaagc cattgataaa cgaaatgaaa aattgaccca ttatttgacg gaagaattgc
    14581 aggtattaaa tgaagaaatg attcgtaagg atattcctac tagttctagt gtgaacgata
    14641 tacaggtgtg gcaggtttct caagtgaatg agaacacctt tgaggtactg ttttctgttg
    14701 aacaagttat taccgaagac aaagacaagg aaactatatc gtctagcttt catgtggttg
    14761 tccatataga tgaatcagat aatatggtta ttatcaaaaa tccgacaatg agtaagaaac
    14821 ctcaaaaatc ggactaccaa cccaaacagc tagaaagtga ccatacagta gatacagaaa
    14881 cgatggacga aatcactagc tttttagaaa cgttcttcca gctctatcct accgccacag
    14941 aaaaagaatt gacttactat gtaagtaatc atgtgttacc tatgattaac aaggaatatg
    15001 ttttcgagga attggtgaat cctatcttta ccagaaaaga taaccaagta atcgtgaatg
    15061 tcgctgtgaa atatttagat caagaaacaa aggcaaccca aatctcgcaa tttgagttga
    15121 tattagaaaa acaag
//
LOCUS       DAIGQM010000066        14466 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.068, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000066 DAIGQM010000000
VERSION     DAIGQM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.068"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..1235)
                     /locus_tag="NOA48_002183"
     CDS             complement(<1..1235)
                     /locus_tag="NOA48_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI0790423.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="NOA48_002184"
     CDS             complement(1228..2820)
                     /locus_tag="NOA48_002184"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI0790424.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..4055)
                     /locus_tag="NOA48_002185"
     CDS             complement(3330..4055)
                     /locus_tag="NOA48_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790425.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4209..4535)
                     /locus_tag="NOA48_002186"
     CDS             complement(4209..4535)
                     /locus_tag="NOA48_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790426.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4572..4937)
                     /locus_tag="NOA48_002187"
     CDS             complement(4572..4937)
                     /locus_tag="NOA48_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCI0790427.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4974..5189)
                     /locus_tag="NOA48_002188"
     CDS             complement(4974..5189)
                     /locus_tag="NOA48_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790428.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5318..5653
                     /locus_tag="NOA48_002189"
     CDS             5318..5653
                     /locus_tag="NOA48_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790429.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5729..7726)
                     /locus_tag="NOA48_002190"
     CDS             complement(5729..7726)
                     /locus_tag="NOA48_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790430.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7824..8099)
                     /locus_tag="NOA48_002191"
     CDS             complement(7824..8099)
                     /locus_tag="NOA48_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790431.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8331..9065
                     /locus_tag="NOA48_002192"
     CDS             8331..9065
                     /locus_tag="NOA48_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790432.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9104..10246
                     /locus_tag="NOA48_002193"
     CDS             9104..10246
                     /locus_tag="NOA48_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0790433.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10580..11491)
                     /locus_tag="NOA48_002194"
     CDS             complement(10580..11491)
                     /locus_tag="NOA48_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790434.1"
                     /translation="MGERTFEDVKDYVELQSQEKCTVLSAKPEQEFNDLGTEVTVWNV
                     KTDTDGDWWVVEGDNVPMNLYPQSAYYFGTDEVYSFHMGLMERMRVLHEKYDPEDFVR
                     SVTLDTEIAPQLFRKLKNVATLIDSAEEIEDFQSIGVQCREILIELGNHIFIADMAGT
                     KEQPQKSNFKKKAELFIQFYLTGSDNSDYRSIIKKLTESTWDYANKLTHSSTTTKYEA
                     STCVMLVTSLVGVYENITQKVFDPVSQYICSSCKSKKLTIDSDDSDENGMVESLYLKC
                     EECGDITKVVFLTSDKDSSYTKGKIIE"
     gene            complement(11596..13026)
                     /locus_tag="NOA48_002195"
     CDS             complement(11596..13026)
                     /locus_tag="NOA48_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790435.1"
                     /translation="MDDIKEVFLEVLSRYIQDNLLEYQNNGKKYEFSFDIKNYNDSLH
                     VVFQYNKAGKIGITDVHSFQIFLNEINIEASKSHLNYTTILDTNSLFFSKKLLPYLHS
                     YEWALRKLIYLLAPTYFDNWTKDSIPDEMISAVKGKQKQAIGKYDLENLLQWIDLYDF
                     EEYLFGENYLFISTGNEKNIVRYKEIIVEELLNLFRETDDLSLSDPFSLWSEVFSKYM
                     YVDLEEIRKDMELIREGRNIVSHNKEIKYSLYKDLIKNLKKYVKQLNEAFKKILIGEI
                     ADEKLFDMTNDFEAYIGNHYSNINLPNATKLLTSLSAMTVLNTDSTKKMMETIGPALS
                     VQRAVMQNIDTEGFRRATEGMKQSLSAMTVLNADSTKKMMETISSALSAQRAVMQNID
                     TEGFRRATEGMKQSLSAMTVLNTDSTKKMMETIGPALSAQRAVMQNIDTEEFRRATER
                     MKQSLSPKQALKSDYKIADDIEDSNK"
     gene            complement(13195..14124)
                     /locus_tag="NOA48_002196"
     CDS             complement(13195..14124)
                     /locus_tag="NOA48_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790436.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHVRNYSQHGHLPVNIE
                     QQRVYFDLDEILTMPHFDLNEKLKSEIDEIKEDISARFEDFPRISYVYTIAKFNLITT
                     EIYLNYLKEVKPILMEMDKEKNELLLNTKFKLTNSDGKSSDVVFYDFDGENYHCFNRT
                     DNSLSMYASIKKEVKKILREEEQYYKEIKNKNQ"
BASE COUNT         4589 a         2700 c         2050 g         5127 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat
     4081 aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca
     4141 aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata
     4201 catttaaatc aatttaacat taacacctca gtatatggta tctctacata tacacggtct
     4261 ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta
     4321 gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt
     4381 aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca
     4441 gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac gatacctata
     4501 atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg
     4561 attttctctc atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct
     4621 acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc
     4681 ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa
     4741 atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc
     4801 atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct
     4861 gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca
     4921 cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg
     4981 tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa
     5041 agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat
     5101 tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg
     5161 tatcggctga gattacttac ttttttcatg attctcccct cctgttttat tatatacaac
     5221 aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa
     5281 caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa
     5341 ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat
     5401 cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga
     5461 tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt
     5521 tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc
     5581 aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct
     5641 attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa
     5701 ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc
     5761 ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa
     5821 ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc gctagatata
     5881 ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt
     5941 caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc
     6001 tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca
     6061 ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca
     6121 attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt
     6181 tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt
     6241 tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa
     6301 cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct
     6361 ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta
     6421 tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt
     6481 taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac
     6541 tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca
     6601 tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt
     6661 caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt
     6721 tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa
     6781 ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc
     6841 cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta
     6901 agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct
     6961 cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt
     7021 ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc
     7081 tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag
     7141 taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa
     7201 aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt
     7261 attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa
     7321 tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat
     7381 tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac
     7441 tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta
     7501 ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa
     7561 atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat
     7621 ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt
     7681 tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct
     7741 tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct ttattactat
     7801 atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca
     7861 gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca
     7921 tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata
     7981 tactctagag tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc
     8041 tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata
     8101 tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt
     8161 tctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt
     8221 catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat
     8281 ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac
     8341 gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa
     8401 gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa
     8461 ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat
     8521 tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag
     8581 aagaatatat tttgggaatt attctttata gagatagcat tgtactagat ggtataacat
     8641 ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt
     8701 tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta
     8761 acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag
     8821 aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta
     8881 gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag
     8941 acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac
     9001 aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca
     9061 tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa
     9121 gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc
     9181 acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca
     9241 aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga
     9301 tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc
     9361 ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa
     9421 gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag
     9481 taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac gctacggggt
     9541 tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga
     9601 gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt
     9661 taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat
     9721 gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact
     9781 acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa
     9841 aacaagagct tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa
     9901 ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga
     9961 gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg
    10021 gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca
    10081 tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt
    10141 agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc
    10201 taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa
    10261 atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg
    10321 ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt tcaatagcat
    10381 tggtacatga ttcgcgttat aaaagcattt ttcccgctct ggtatatatc actgacagcc
    10441 tatcacagca cttgatatcc cccagaacgt atccaatatc gtacccaaaa aagcaggtag
    10501 agaagttatt tgaggtatca aatttaaaaa cgtgtgcact ttgaattgcg tgatatgttt
    10561 ttgacatgat ccataatcat tactcaatta tttttccttt tgtgtatgaa ctatccttat
    10621 cactagtcaa aaatactact tttgtaatat caccacattc ttcacatttt aaatacaagg
    10681 attcaaccat tccgttttca tcagaatcat cagaatctat cgtgagtttt ttacttttac
    10741 acgacgaaca tatatactgt gagacaggat caaagacttt ttgcgttatg ttttcataca
    10801 caccaaccaa agacgttaca agcattacgc aagttgaggc ttcatactta gtagttgtac
    10861 tagaatgagt taatttatta gcgtagtccc atgttgattc agttagtttt tttataatac
    10921 ttcgatagtc agagttatcg gaacctgtca aataaaactg tataaaaagt tccgcctttt
    10981 ttttgaagtt tgatttttgt ggttgttctt tagtacctgc catatctgct ataaagatgt
    11041 gattaccaag ttcgattaga atttctctac actgaacacc aatagattga aaatcttcaa
    11101 tttcttctgc actgtctata agagtagcaa cattctttag cttccgaaag agttgtggtg
    11161 caatctctgt atcaagagta acgctcctta caaagtcctc tggatcatat ttttcatgta
    11221 aaactctcat tctctccatt aaacccatat gaaacgaata tacctcgtct gttccaaaat
    11281 agtatgcact ttgcggataa aggttcatag gaacgttatc accctcaaca acccaccaat
    11341 cgccgtcagt atccgttttg acattccaaa ccgttacttc tgtaccaaga tcattaaatt
    11401 cctgttccgg cttggcactt aacaccgtac acttttcttg gctctgcaat tctacatagt
    11461 ctttaacatc ttcaaaagtt cgttcaccca ttatttacct ccatgatttt taccaaatag
    11521 attgtatttt tctagtttta tttcacctct ctaattcttt taatagttta ttaattggaa
    11581 aaagttctgg actctttatt tattactatc ttcaatatca tcagcaattt tataatcgga
    11641 tttcaatgct tgctttggtg atagagactg cttcattctc tcagttgctc gtctgaactc
    11701 ctcagtatca atgttttgca tgactgctcg ttgagcggat aatgccggac cgattgtctc
    11761 catcattttt ttagtagaat cagtatttaa tactgtcatc gctgatagag actgcttcat
    11821 tccctcagtc gctcgtctga acccctcagt atcaatgttt tgcatgactg ctcgttgagc
    11881 ggataatgcc gaactgattg tctccatcat tttttttgtg gaatcagcat ttaatactgt
    11941 catcgctgat agagactgct tcattccctc agtcgctcgt ctgaacccct cagtatcaat
    12001 gttttgcatg actgctcgtt gaacggataa tgccggaccg attgtctcca tcattttttt
    12061 agtggaatcg gtatttaata ctgtcatcgc tgataaagac gtcaataatt tagtagcgtt
    12121 gggtaggttt atattactat aatgattccc tatatatgct tcgaaatcat ttgtcatatc
    12181 gaaaagtttt tcatctgcta tttcaccaat tagtattttc ttaaatgctt cattaagttg
    12241 tttcacgtat ttctttagat tctttatcag atccttatat aaagagtatt taatctcttt
    12301 attatgactc acaatattcc ttccttctct gatcaattcc atgtcttttc gaatttcttc
    12361 taaatcaaca tacatatact tgctaaatac ttcactccat aatgaaaaag gatcagatag
    12421 acttaaatca tcagtttctc gaaataaatt taacaattct tctacgatta tctctttgta
    12481 ccttacaata tttttctcat ttccagttga aataaatagg taattttctc caaataggta
    12541 ttcttcaaaa tcgtataaat ctatccactg taaaagattt tctaagtcat acttgccgat
    12601 tgcttgtttt tgttttcctt ttactgcaga aatcatttcg tctggaatag aatctttcgt
    12661 ccagttgtcg aaatatgttg gagccaataa atatatcaat tttcttaaag cccattcata
    12721 actatgcaaa tatggtagta atttttttga aaaaaataat gagtttgtat ctaaaatagt
    12781 agtgtaattt aaatgtgact tgctcgcttc aatattaatt tcatttagaa aaatttgaaa
    12841 tgaatgtaca tcggttatcc ctattttacc agccttatta tactgaaata ctacatgtaa
    12901 cgaatcatta taatttttaa tatcaaaact aaattcgtat ttttttccgt tattttgata
    12961 ttctaaaagg ttgtcttgta tatatcgtga taatacttcc aaaaaaactt ctttaatatc
    13021 atccattttg ccttgtttag ggtaatataa atattcaaca acttgcttgc taatatgtcc
    13081 tcgccttctt ttctttcaac gatttaaaat tttccaaata acttgataac tactaagtaa
    13141 gcctcaaaca acaaccacaa atgaattttt cactaatatt gatgattgtg atatttactg
    13201 gtttttattt tttatttctt tataatattg ttcttcttct cttaatatct ttttaacctc
    13261 cttttttatg ctagcataca tcgataaact attgtctgtt cgattgaaac aatgataatt
    13321 ctctccatca aagtcataaa aaaccacatc acttgatttt ccatctgaat tagttaactt
    13381 aaatttagta ttgagtagca attcattttt ttctttatcc atttccatca aaattggttt
    13441 aacttctttt aaatagttca aatatatttc agttgtaatc agattaaact ttgcaattgt
    13501 gtacacatat gagatacgtg gaaaatcctc aaatcgagca gatatatctt ctttaatttc
    13561 atctatttct gattttaatt tttcattaag atcaaaatga ggcattgtta gaatttcatc
    13621 caaatcaaag tatactcttt gttgttcaat atttaccggt aagtgaccat gctgagaata
    13681 atttctaaca tgtaataaaa atctgtacga gaaatgttca tcataaggct tactcagaat
    13741 tttattctta aaagatttaa aatctttttc tgctaaaaag tttttcatac aaacttcaat
    13801 ggattcagtc aaagttttgg ctgaactaat taagtttatc gtcaaagcat ttatctgata
    13861 ataatactgg tcttccgtta atttttcacc tgtactttca attaaatcat tagtaaaaat
    13921 tgtgaagtgt ttgagcaaat tagttaaatt atatctaaac acattaaaaa gtttatccaa
    13981 ctctataata tgacgtgtta attctacata atttaaaaat attcttttat cagattctgt
    14041 tattgtttct aataatgaat caatctgcct tattagctcg tcatcttgta aattactgac
    14101 gaaaaaccta ctatcacttc tcataattat attctcctaa tatgattttt tcaaaataat
    14161 caatatgtaa catagaagta tactctattg ttacatacct tatttcttat tatatcagta
    14221 tttctctgtg acacataagg gtgtaacata attattttaa acgaaatgac tacaagtagt
    14281 cattgaagca aatctccata agacatttgt aaaatctttt aaaaagaagc gtcgaaagaa
    14341 ggaacttttc ttcaacgctt cttttattga ctcaattttc aatattactt gaacgaataa
    14401 tctgatttct aaactctcga aaaacttctt gtggttgata atagtctgga tctatttcaa
    14461 atgttt
//
LOCUS       DAIGQM010000067        14027 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.069, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000067 DAIGQM010000000
VERSION     DAIGQM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.069"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..411)
                     /locus_tag="NOA48_002197"
     CDS             complement(<1..411)
                     /locus_tag="NOA48_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790437.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLDE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNI"
     gene            complement(514..1809)
                     /locus_tag="NOA48_002198"
     CDS             complement(514..1809)
                     /locus_tag="NOA48_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0790438.1"
                     /translation="MNDSIKKMLRLIDKNLMITGVSYETFQKEKTLIVDAILSPAPCA
                     CSNCGSTVVDGTGKTIVVKNGKKETIVRFEQYNHMPMVMRLKKQRYTCKNCRTHWTAQ
                     SYFVRPRHSIANHVRYKITSLLTEKVSLSFIAKSCQVSLTTVIRILKEFKSYLPKSSK
                     RILPKVLMVDEFRSHASIEDKMSFICADGETGKLIDILPTRKLPRLTSYFLSCTNPEE
                     VEFLITDMNAAYFQLTKRVLPNAKVVIDRFHIVKHINQAFNDLRIREMNELRKAGKKR
                     QAEKLKKNWRFLLKKRSNINHYEYKTWKSFRAPKYPFFTEAMMIDRLLGFSTPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLEELPETLDDAFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVK"
     gene            1990..2300
                     /locus_tag="NOA48_002199"
                     /pseudo
     CDS             1990..2300
                     /locus_tag="NOA48_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
     gene            2808..4100
                     /locus_tag="NOA48_002200"
     CDS             2808..4100
                     /locus_tag="NOA48_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCI0790439.1"
                     /translation="MDGITIPWYAAIIGLIFAVFLILKKMNPVYSLFLGAIIGCLIGG
                     ASLSNTVDILVTGTQSIMGTAIRVLAAGMLAGVMMESGAAESIAHAIVNKLGSNKAIF
                     SLALSTMIITAVGVFIPVAVLIVAPIALSVGKQTGISKLALLTALSGGGKAGNIISPN
                     PNTIAAANGFKLDLSNVMIAGFIPAIFGLATAVLIASLIKKKGGKVKDSDIQEKSEKE
                     LLPLRKALIAPVLSIVLLLINPIGTMLHIQVLADLKIDAMYILPFASIVGTIAMGQAS
                     QIREYSKSGIYRVTDTVLILIGAGAIAGLISVSDLSKQVVHLISITGISGTLLAPISG
                     ILMGLAVGSTSTAVILATGSFGHAILETGTNSLAAAVMVHTGATVIDSVPQGNYFHIT
                     ANSMNMSIKERMKVIPYEICVGGVMTIVATILYGFILK"
     gene            4235..5380
                     /locus_tag="NOA48_002201"
     CDS             4235..5380
                     /locus_tag="NOA48_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0790440.1"
                     /translation="MEKTFVLAPDSFKESMSAKNACEAMERGIRKVFPESKVIQVPMA
                     DGGEGTVDALVDGINGTKIEVMVSGPIPSEKIKAYYGLLADESTAVIEMAEANGIELL
                     AENKRNPLLTSTYGTGEMIKDALDKGVKKIIIGIGGSVTNDGGAGMAQALGVQFLDKN
                     DKELPVGGGALSELAKVDVSTIDPRLKETEVVIASDVTNPLTGPNGASFVFGPQKGAT
                     PDMVKKLDENLVHYAAVIQKNLGIDIKDQPGSGAAGGLGAGLLVFTGAKMESGVDLVI
                     QLTHLEEKIVQADYVFTGEGGMDFQTKFGKAPYGVAKIAKRYDKPVFACAGYIGEQVD
                     VLYEEGMTAIFGILDQAGPLKQALQAGESNLERTVENIVRVLNVCGG"
     gene            5450..6463
                     /locus_tag="NOA48_002202"
     CDS             5450..6463
                     /locus_tag="NOA48_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790441.1"
                     /translation="MSNLLTKEQANMIVSKLMADIPYNINIMNEQGFIIASGKEYRIG
                     ERHRGAERAIKQGEMVEIFKDTSLEKRGTNEPIILNGELLGVVGISGDPEEVRPFTKL
                     VKSIVLLLVEELNEFRKKEKKNQLKADFLKELLSIKDCYSEEMVHQALDDYGINLLRT
                     NRCIGSLEQETLRSCFPLHEVFEWYGMYIVFIDGNTIIDDDLSGLIVSSEQWNLGQGM
                     NEVDNTFLYLKFFQIPINKVFFSEDLYFIHLFDFSIKLDKNLLKKVESIYDEYYETLI
                     YFSSNNGNVKEVSEKLHIHRNTLNYRIQRIQELTRKDPKNWSHLWILMYHLAYCFKVK
                     FRT"
     gene            6855..8054
                     /locus_tag="NOA48_002203"
     CDS             6855..8054
                     /locus_tag="NOA48_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790442.1"
                     /translation="MRDQTSGKMIRFYYTSLQFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFISQVIIKKRKIPLITVLKTMTAGLGVILLAGVLLPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVVFFVILHLLPDVKNQEVFPMTKEQDRPVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSIASISFAVRGFMMLLAGSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTSFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8549..9307)
                     /locus_tag="NOA48_002204"
     CDS             complement(8549..9307)
                     /locus_tag="NOA48_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0790443.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLF
                     KDDIVIFVSLNGETKELITAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9475..10410
                     /gene="pfkB"
                     /locus_tag="NOA48_002205"
     CDS             9475..10410
                     /gene="pfkB"
                     /locus_tag="NOA48_002205"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI0790444.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10407..11852
                     /locus_tag="NOA48_002206"
     CDS             10407..11852
                     /locus_tag="NOA48_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0790445.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSIIAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAVLFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAATVEMKEETNN"
     gene            11880..12335
                     /locus_tag="NOA48_002207"
     CDS             11880..12335
                     /locus_tag="NOA48_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0790446.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12354..13328
                     /gene="lacD"
                     /locus_tag="NOA48_002208"
     CDS             12354..13328
                     /gene="lacD"
                     /locus_tag="NOA48_002208"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0790447.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNQSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13438..13923)
                     /locus_tag="NOA48_002209"
                     /pseudo
     CDS             complement(13438..13923)
                     /locus_tag="NOA48_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
BASE COUNT         4378 a         2264 c         2969 g         4416 t
ORIGIN      
        1 tatattggac atggtttggg gcgtgtagtg atgcccatac attttctcaa tcaagtctgc
       61 gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcat ctaacgtgtc
      121 attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcgccattgc ggtcgcgcgg
      181 aatctggaga tgaagttccc catactcggt cttgaccgta cggtcatagg agccgttacg
      241 agaattaccc gtgttaaaac caatgcgatc atacttttcg taatcgagga aagccgttaa
      301 ctccgttttg agaagcgtat tgactgcttt ctccaaatgg acacggaata attcattcaa
      361 atcgcctttg ttcgctagag tctttagaat ttctgtagta aaatcgttca tagggaagtc
      421 ctctcttctg ggctctttgt caataaggac tgatgaagct gtgcaaaatc aaatctgggt
      481 caggatgaac ctcattctgg ctcagatttt ttgttatttc actttgatta attgattgat
      541 caaaaagatt ctaattctca tgttctcaaa tgatttaaat ccgtaggata ctcgtttcat
      601 tgtctttata tgggtattct ttgcttctat ttttccatta gaataaggat agatcatcgc
      661 attggtgatg ccttcttcat aggtcagaag attttgaagt ttctcacgaa aggcatcatc
      721 taacgtttca ggaagttctt ccaataaaga gaaaaataag tcagggtctt tgtctcgaaa
      781 ggcttctact aactcatgaa aaaagggata cgcctccttc aggggcgtgg agaaaccaag
      841 caatcggtca atcatcatcg cttcagtaaa aaatgggtat ttaggcgctc ggaaactttt
      901 ccatgttttg tattcataat ggttaatgtt tgaacgtttt tttaacagaa agcgccagtt
      961 ctttttcaac ttttcagcct gccttttttt acctgcctta cgcagctcat tcatttcacg
     1021 gatacgtaaa tcgttgaatg cctgatttat atgtttgaca atatgaaatc gatcaatcac
     1081 tactttcgca tttggaagaa cacgtttggt gagctggaaa taggcggcgt tcatatctgt
     1141 gattaaaaat tctacttctt ctggattggt gcaacttaag aaatagcttg ttaatcgagg
     1201 taatttacgc gtaggcaaga tatcaattaa tttacctgtt tcgccatctg cgcaaataaa
     1261 gctcatttta tcttctatag aagcgtgcga acgaaactca tcaaccatca atacttttgg
     1321 gagaatcctc ttagaggact ttggtaaata gcttttaaac tctttcaata tacgaataac
     1381 ggtggtcaaa gatacctgac aacttttcgc aataaaagat aaagacactt tttcagtcag
     1441 taaagaagta attttatatc tgacatgatt cgcaatggaa tgtctggggc ggacaaaata
     1501 actttgagca gtccaatggg ttcgacagtt tttacaggta tagcgctgct tttttaagcg
     1561 cataaccatt ggcatatgat tgtattgttc aaagcggaca atggtttcct tcttgccgtt
     1621 tttcaccaca attgttttcc cagttccatc taccacagta gaaccacaat tgctacaggc
     1681 acaaggagca ggtgagagaa tggcatcgac aatcagagtc ttttccttct gaaaggtctc
     1741 ataagagacc cctgtaatca tcaaattttt atctattaat ctcagcattt ttttgataga
     1801 atcattcata tagcatatcg tcctctcagt ggtttatttt gtcgtgattt aatcatacta
     1861 gagaacgata tgttttttaa tatctaaaat gaaaatgaga ctgaagaatc aattctgatt
     1921 catcagtctc ataaattata gagccacaaa actctgtggt ctttttttgt agtaaaggag
     1981 gaatttggag tggccaaact agatgaagaa tttgcttttt tggtattgtc gatcatatcg
     2041 gagattccca aaggcaaagt agctacctat ggacaaattg ccgagttggc aggatatcct
     2101 cgcaattccc gtttagtcgg taaagtattg agccacgccg aatattatgg tcgctatcct
     2161 tgtcaacgag tagtgaatag tcagggagaa tgtgcgaaag gttggccgga acagccgtta
     2221 ctattgcaag agagggtatt atttttcgcg agaatggacg agtggatctg aaacgctgcc
     2281 attgggatgg agaagagtga tctgtaaagg atcattcact ttaagcaata cagatatgat
     2341 gaaataaaat atctatgaat ttttttgcgt tgcaatggag agattctttg ggagtttgat
     2401 tctaaaataa atcatataca atgggttatt tagtgcccga ttttgttagg agtataggca
     2461 aaaagaatta gtagtgaaaa tcagtattgt atttgggata tattctttta tttaatatga
     2521 gttaggtcct tagaactaaa agaattaaga gattgattga ctttgtaaat agtaaaatac
     2581 ctaataagta tcaatgagtt cccaaatcgt atctagttga atagaagaaa tttctattga
     2641 atactatgtg attctatgaa tttatttaag ttgtctaaaa tagtgaaatt ctgaatttat
     2701 attatcgata tgtgcaaatg aacaaataac attgtaaata taccaatttt atttatgaaa
     2761 taaagcatta aaatgaaaac gtaaacaatt aagaaaggat gtttgaaatg gatggaatta
     2821 caataccgtg gtatgcggcg attattggtt tgatttttgc agtttttttg attttgaaaa
     2881 aaatgaatcc ggtttattca ttatttttag gagcaattat cggatgtttg atcggcggag
     2941 catcactaag caataccgtg gatatattag ttacaggaac acaaagtatt atggggacag
     3001 caattcgtgt gttggcagca gggatgttgg caggagtgat gatggagtca ggcgcagcag
     3061 aatccatcgc ccatgcaatc gttaataaac ttggaagtaa taaagcaatc ttttcactag
     3121 ctctgtcaac aatgatcatt acagctgtgg gcgtatttat tcctgtcgca gtattgatcg
     3181 tagcgccgat cgctttgtca gtcggaaagc agacaggtat cagtaaatta gcattgttga
     3241 cagcattgtc tggtggcggc aaagctggaa atatcatttc gcctaatccc aatactatcg
     3301 cagctgctaa tgggtttaaa ttagatttaa gcaatgtaat gattgctgga tttattccgg
     3361 caatttttgg attagcaaca gcagttctta ttgctagttt gattaagaaa aaaggcggta
     3421 aggttaaaga tagcgatatt caagaaaaat cggaaaaaga attgcttcca ttacgcaaag
     3481 ctttaattgc acccgttttg tcaatcgttt tattattgat aaatccaatt ggaacgatgc
     3541 ttcatattca ggtgttggct gatttgaaga tcgatgcgat gtacatttta cctttcgctt
     3601 cgatagtggg gacgatcgca atgggacaag ctagtcaaat cagagaatat tcaaaatcgg
     3661 ggatttatcg tgtgacagat accgttttga tcttgattgg tgctggtgct atagctggtc
     3721 tgatctcagt ttctgattta tcaaaacaag ttgtccattt gatttccatt acagggattt
     3781 cgggtacatt attagcgccc atctcaggta ttttaatggg cttagcagta ggatcaactt
     3841 ctacagcagt aattttagcg actggatctt ttgggcatgc tattcttgaa accggaacca
     3901 attcgttagc agcagctgta atggttcata caggtgcaac ggtgattgat agtgtacctc
     3961 aaggaaacta tttccacatt acggctaaca gtatgaatat gtctatcaaa gaacggatga
     4021 aagtgattcc ttacgaaatc tgtgtcggtg gtgtgatgac gatcgttgca acgatattat
     4081 atggatttat tttaaaataa aattgtagag atagcgtttt gtcaaatctt ttacaaaaat
     4141 atgaacttga aaaaatattt attgaaaata acaatgaaga aggtaaattc tgtttgaaaa
     4201 gaagattttc agcagaattt tgaggagaag aacaatggag aaaacttttg tattagcacc
     4261 agattcattt aaagaaagta tgagtgctaa aaatgcttgt gaagcaatgg aacgaggaat
     4321 tcgcaaagta tttcctgaat ctaaagtgat ccaagtccct atggcagatg gaggagaagg
     4381 aactgttgac gcactagttg acggtattaa cgggacaaaa atcgaagtga tggtgtctgg
     4441 accaattcca tcagaaaaaa tcaaggctta ttacgggttg ttagcagatg aaagtacggc
     4501 agtgattgaa atggctgaag ccaatggtat tgaactattg gcagaaaaca agcgaaaccc
     4561 tcttttgacc tctacttacg ggactggaga gatgatcaaa gatgccttgg ataaaggagt
     4621 aaaaaaaata atcatcggta taggaggcag cgtcacgaat gatggcggtg caggtatggc
     4681 tcaagcgtta ggagtgcaat ttttagacaa aaatgacaag gaactaccgg ttggaggcgg
     4741 cgcgttgtca gaattagcta aagtcgacgt tagcactatc gatccaagac taaaagaaac
     4801 agaagtcgtt atcgctagcg atgtaaccaa tccgttgacg ggtccaaatg gcgcatcatt
     4861 tgtttttggt ccgcaaaaag gagctacgcc tgatatggtt aagaaattag atgaaaattt
     4921 ggttcactac gctgcggtta ttcaaaaaaa tttggggata gatatcaagg atcagcccgg
     4981 ttctggtgca gcagggggat taggagccgg actattagtt tttactggcg caaaaatgga
     5041 atccggtgtc gatttggtta tccagttaac acatttggaa gaaaagattg tacaagctga
     5101 ttacgtgttt accggtgaag gcggtatgga ttttcagaca aaatttggga aagctccata
     5161 cggtgtagca aagatcgcca aacgatatga caagcctgtt tttgcttgtg ccggttatat
     5221 cggcgaacag gttgatgttt tatacgagga aggaatgact gcgattttcg gcatcttaga
     5281 ccaggccggt ccattgaagc aagcattaca agccggcgaa tccaatttag agcgtacagt
     5341 tgaaaatatc gtccgtgttt taaatgtttg tggaggttaa aagttgtgtt atctatcaaa
     5401 aaaagattaa actaactgta taaccagata attcttagga cggtaatcaa tgagtaattt
     5461 attaacaaaa gagcaggcca atatgatcgt aagcaagctg atggcggata ttccttacaa
     5521 tattaatatt atgaatgaac aaggttttat tattgcaagc ggtaaagaat atcgtatcgg
     5581 tgaacgacat cgtggtgcag aaagagcaat taaacaaggc gaaatggttg agatcttcaa
     5641 ggatacttcc ctagaaaaaa gaggaaccaa cgaaccaatc attttaaatg gcgaattatt
     5701 gggagtagtt ggaatctcag gagacccaga agaagtccgc ccgtttacta agctagtaaa
     5761 atcaatcgta ctgcttttag ttgaagaact aaatgaattt cgaaaaaagg aaaagaaaaa
     5821 tcagcttaaa gctgattttt taaaggagct cctttcaatc aaagattgct acagtgaaga
     5881 gatggttcac caggcattag atgattacgg gataaatctt ctgcgaacga atcgctgtat
     5941 tggatcattg gaacaagaaa ctttacgtag ttgctttccc ttacatgagg tttttgaatg
     6001 gtatggaatg tatatagttt ttattgatgg caataccata attgatgacg acctctcagg
     6061 tttaatcgtt agctctgaac aatggaattt aggacaggga atgaatgaag tagataatac
     6121 ttttctgtat ttgaaatttt tccagattcc aatcaataaa gtctttttta gtgaagattt
     6181 atattttatt cacttatttg atttttcaat taaactagat aagaatctat taaaaaaagt
     6241 tgaatcaatc tatgatgaat attatgaaac actgatttat ttttctagta ataatggaaa
     6301 tgtgaaagaa gtgtcagaaa aactgcatat ccatcgtaat acactaaatt atcgaattca
     6361 gcgtattcaa gaattaacta gaaaagatcc taaaaattgg tctcatttgt ggatattaat
     6421 gtaccatctt gcttattgtt tcaaagtgaa gttcagaacg taagaaataa gaatatgtat
     6481 ccataataaa tgtttggatt taccttatag atataaaaag aaacaaatca ttctgcagga
     6541 atcgattact cgattcctgc tttttttact tcctttgcag caaaaaagtg ctcgtaatct
     6601 aagcgatgtt ggatagtttt tagaatatat atattttctt caattccaga aaaaaatgac
     6661 caagctagta tgctaaaaaa gtacgatgct tctatgatct tttttccgtc tttattaaca
     6721 gatgttttaa ttgatcaacg catattgtaa tctaccctaa tttccatagt tcttcaccac
     6781 ttttaaaaat agtaaaaccc ctacaagtat gctatagtaa attgctaaag aaaaaccaat
     6841 aaggtgggag atgtatgcgc gatcaaacaa gtggaaaaat gattcgtttt tattatacaa
     6901 gtttgcaatt tctctattgg atgatgtttt gttcggtcta tgggtttgcg acattgtttt
     6961 tgatttattt caagattgat ccagctaaaa tcggagggat cttagcattg gtcaatattg
     7021 tttcaacggt gcttcagcct tttatcagtc aggtgatcat caagaaaaga aagattccac
     7081 tgatcaccgt gctaaagacg atgacagcag gattaggagt gattctctta gctggggtat
     7141 tgcttccgaa tttgccgatc attacttata tcttgggtgg gattttagta gtttccatgc
     7201 aatcatttct caatgcgctg gcatttgagt attcaaatac cggctacagg atcaactttg
     7261 gtttttcaag agctggcggt tcattttctt atgctgtaac ttctttttta ctgggacagt
     7321 tgttagcgat ttattctgcc gcgattttgc cgatcttggt tatagttgaa gcagtagtgt
     7381 ttttcgttat tttgcatctg ctgccggatg taaaaaatca agaagttttt cctatgacaa
     7441 aagaacagga tcgcccagtt tctttgagaa aaaaatatcc tttcctgatt ttgttgtttt
     7501 taggtttcag ttttcttttt actttccaca ccatgatcaa cagttttttg gcacagatct
     7561 ttgaaaacat ccacggtggc agtaaagaag tcggcatcgc attgatgatc gccgctttat
     7621 gcgaattacc gggaatgatc ttttttgaac agcttgtcaa aaagaaatcc agcaaatttt
     7681 ggctgtctat tgccagtatt tcatttgctg tcagaggatt catgatgctg ctggccggtt
     7741 cgatcttgat gatggaaatg acgcatctcc tgcaagcctt tagttttgct ttgtttattc
     7801 cagcttcagc ttatttattc aatcaatttc tggcggatga cgaccgtgta tttggacaaa
     7861 cgatgatcat tatcgccaca actcttggtg gggtgatagg aaatgtcttg ggcggcagtc
     7921 tgctgcagca tttcggtgta tgggagatgc tgattttcgg tactagtttt gcggtgctag
     7981 gtgctttatt aactattttg ggcattcgaa aaataccgaa gacaggaaac gatagtgatt
     8041 ctcttgttga gtagcataaa aatacttaga tactagtttt atataaataa catatagtga
     8101 ttattggtgt aattacaaaa aacgagaata acttaagtaa gcatttctaa ataattgaga
     8161 aacctcatct aaaaagataa gaaaatatcc ctaataaaac ttctgtaaca ttttagataa
     8221 ctgattgtaa gctgaataat aaactataag gagacagtta gacggtctcc tttttttgcg
     8281 tattataatt ctagaattgt tggaaattga taataattaa caagaaatat tagacaggaa
     8341 cttcgaactg cttatcacat tcttattatt atatatttgc gtaagtagtc ctggtagtct
     8401 caatgcacta ttctatcttg aaactaagaa gttatagaag gagcaatgat agaaagcacg
     8461 agaatacaaa tagcgattaa atatttttct agacaacctt agttaattca cacagatata
     8521 ttttaggtac agtcttacag atatagagtt agtgctgtgt gaatcctgat gttcgcagtg
     8581 cataggagtc aagtaagatt ctagccagta tagaaagtgg aagtctggag cgtacctcat
     8641 aatctgggaa gaaggagcct tctgatttaa agccaacaaa aggaatctcg atatgttcca
     8701 tcaaacttga atgacgatta gcagtaagca aaattgtccc gatctcagct ttataacagt
     8761 tttcagctgc ggtaatcaat tcctttgttt caccgtttag tgaaacaaag atcacgatgt
     8821 catctttgaa taattttcta ctaatgtttt ttatgatatt gggatcagta tgcatctcac
     8881 aatatttacc ggtaagttga aatttgacca tcatttcctg agcaatcaat tctgaaaaac
     8941 ctcgggcaaa aatcatgatt cttctagcag ccttgattcg ttgaatagca tcttcaatat
     9001 tcccgctttc taccatattg atggtgcgga ttacctcttg ctcattttta agaatagcag
     9061 tctttattcc ttcatcaact ttatcaagag cggcaaaatt gatatttgta ttttcttttt
     9121 cttttaacga atgtttaaaa gacgtaaacc cctcatatcc ttttttcttc atagtacgaa
     9181 cgacggttgc tgttgaaacg ttggcatatt cacttagttt tacaatggaa taggagggga
     9241 tttcgagtat gtgactttga ataaaatccc agagatattt ctccgattca cttaattttg
     9301 tatccatatt ttgcctccga ttagttagga taattctatt gtaaagcggg agtttccttt
     9361 acttcaagtt tatttaatat attttgtaaa agttttcaat gaatttagtc atttatgaaa
     9421 acatttacat tcgatcttga tacataatga atatgtaaga aaggaggagc gtaaatgtca
     9481 gtttatacat gtactttaaa cttggcaatc gaccttttta tcgaaacaga tgaaatgaaa
     9541 ccatcccaag tcaatcgaac aaacgatgat gatatacaag ctaatggaaa aggggtgaat
     9601 gtttcattga tcatgaagca attaggtatc gatagtacag ctttaggatt taaagcaggt
     9661 tttaccggga attatattga ggattatttg catcaaaaag atattagcac tgattttatt
     9721 agcgtaccgg gaatgactag aatcaacgtt tttacacaag ttaataaaac caatgaagaa
     9781 ttcaaattgg ttaataaagg acctgagatt cctcaggaac aaatcaaaac ttttctaaat
     9841 caaatacaaa agctgcaagc tgacgattat ttgtgtgttt ctggcagttt gccgcgaggg
     9901 gtctcacccg aaattcttat tgatatcagt cgtatttgtt ttgaaaataa ggtccatctg
     9961 attattgatt caagctatcc ggaaataatt gattgtctgc cgtatcagcc gttcttatta
    10021 aaaccaaacg aggaggaatt gcaatcttgg tataatgtcg agcttagtga tcgtgaagga
    10081 tatattcatt atgctgaacg cttgattgcc gatggagcga aaaatgttct cctttctcta
    10141 ggaggagagg gaggaatatt tttaaataag gatatcgttt attctgggaa ttctcctaaa
    10201 ggtaaagtag tcaatacagc gtgtgctggt gacactttgt tgggaacatt tcttgcagga
    10261 tatttaaaag gtgaacaggt agatattaat ttgaagaaaa gtttagcagc tggaagttca
    10321 accgcttttc gtaaaggatt aacagatttt tcggatgttg cagagttgga aaaacaaatc
    10381 gaaatcaaag agggagcgag taaaaaatga caacttacaa aattgttgcc gcaacaggat
    10441 gtccaacagg aattgcccac acttatatgg ctcaagaagc attggagcag gcagctaagc
    10501 gcaaaggggt atctatcaaa gttgaaaccc atggtcaagt agggatagag aatgaattaa
    10561 caccagaaga aataaaaaac gctgacgctg taatcattgc agctgacaaa gatgttcaag
    10621 cagaacgttt cgcaggtaag cgtgtaatcg atgtgcctgt cagcaagggg attaaagatg
    10681 ctgaccaatt gatcgaagat gcgttggctg gtaaaggttc aatcattgca gaaaacaaaa
    10741 cagttgacgc tgctggtgag aaagcggaga tgggggttgc agcaggcatt ggtcacagta
    10801 tttataaaaa tctcatgaac ggtgtttctc atatgctgcc gtttgtagtg gcaggtgggg
    10861 taattattgc aatttcgttt gccatctggg gtgtgtactc ttttgatccc aatgatccta
    10921 cttacaatcc gactgccgct atgttaaagg gtgttggtga tgcggcaatg ggaatgatgg
    10981 ttcctatttt agcagcttat atcgctgaag gaatcgctaa acgtcctggt ttggttgttg
    11041 ggtttgttgg cggactgtta gccaattctg gcggagccgg tttcttaggc ggaatttttg
    11101 caggtttctt agcaggctac tttatcttac tattgcaaaa ggtcatgaaa ggcttgccta
    11161 aacaattgga tggtctgaag gcgatcttct tatatccggt gatcggtgtc ttgtttgttg
    11221 gtgtagtcat gtctttatta gcaaatccaa tggaagcagt caaccaagga atgatgaatt
    11281 tcttggcagg attccaaaat tctaatccat taattttagg gattatcgtt ggctgtatgt
    11341 cagcatttga tatgggaggt ccagtcaata aagcggctta tgttacaggg actgcgttgt
    11401 tggcacaagg taaccataca tttatggcag gggtttcggc agcttgtatc gcgcccccat
    11461 tgattactgg atttgccgta ctgttttttg gaaaatattt cgacacgaat gatcgcaacg
    11521 ctggtttagt caactttatc ttgggctcaa cgcacattac cgaaggagca attccatttg
    11581 cggctaaaga tccgctgcgt gttctgccaa ctatgatgct aggttcatca attgctgctg
    11641 tactgacata tatgtttggt gtccaagttc ccgcacctca tggaggtttt ctagtattac
    11701 ctgttgttac tggtaaggtt gcatgggtag ggtcgatttt acttggttca atcgttggcg
    11761 gagtaatttt agggttgatc caaaaacgta gtgtagaaaa acgtgaagca gaagcagcta
    11821 ctgttgaaat gaaagaagaa accaacaact aaaggttatt ctagaaagaa ggatttcaaa
    11881 tgactttgat caaaacaaat aaagttttta tgaataaaaa ttttacgacg caagatgagg
    11941 taatgaactt ccttgcagat cagtcaattg tcttgagcat tagtgaagac cgagatgcag
    12001 tttacgaaaa attgatggaa agagaagaag aaagcacgac tggtatgatg gatggttttg
    12061 ccatccctca tgccaaagat gctagtatca aggatgccga tattgtgatt gttcggttaa
    12121 acggtaaggt cgattggaaa agtttagatg gagaaggaac ggattttgta atcgctctgt
    12181 ttattccaga ttcagaggct ggaacaaccc atctaaaatt tttatctcag gtagccagac
    12241 ttttgatgca caaagatgtg acagaaggtc tgaaacaagc ccagtctgct gaagaaatag
    12301 ctgaactttt aaaccaaaaa ttagaagaaa actaaaaagg aagtagtgaa atcatgcctt
    12361 taacagaaaa aaagaaaact tatattcgtc aactaagtaa tgaaagtggc atcatcagtg
    12421 cgttagcaat cgatcaacgt ggtgccttga aaaaaatgat cggtaaattt caaaatcaat
    12481 cagcaaccga tgaacaaatc atcaatttca aaaaaatcat ttcttctgaa ttgactccat
    12541 atgcttcagc aatcttatta gatccagaat atgggttgcc ggcagccgaa gttcgcgata
    12601 aaaatgctgg tctgttgttg gcctatgaaa aaactggtta cgatgcttca actccaggac
    12661 gtttaccgga tattttatct atttggtctg taaaacgtct aaaggagcaa ggggccgatg
    12721 cttgtaagtt cttgttatac tacgatgtag atgaatctga tgatatcaat gaccaaaaga
    12781 aggcgtttat ggagcggatt ggttctgaat gtgttgctga agatttgcca tttttcttag
    12841 aattggtttc ttatgatgcc aacgatcctg atacttcttc gaaggaatat gccttgaaaa
    12901 aaccgcataa agtaaatgaa atgatgaagg aattttctaa gcctcgctat ggagttgacg
    12961 ttttgaaagt ggaagttcct gttaatatga actatgtgga tggttacact aaaaatgaag
    13021 ttgcttatac caaagaagaa gctgctgctt atttcaaaga acaatccgag actaccaacc
    13081 tgccatttat tttcttgagc gcaggagtaa ctgctgaatt gttccaagaa accttgaaat
    13141 ttgcaaaaga ggctggctct acattcaatg gggtactctg tgggcgcgca acttgggcga
    13201 atggtgtaga accattcgtt actaaaggtg aatatgctgc caaagaatgg atgcagacac
    13261 aaggacgcaa gaacatcgaa gagctgaata atgttttgaa agaaacagca acagctatta
    13321 aattgtaaga aagctttaac tataacctta agtttgtaac ctaatgattt ttaataatca
    13381 atttgagctt ttaaataaag aattggaagc gtcccgacgc ttcctttttc gtttgtctta
    13441 aggcatgata ggttctatgt tgtcgttcaa taagcgcaag aaggtcagca tttttttctt
    13501 agagtatgca aaattgcttt ctacccaatg atttaaaacg gagaggcacc cttggatatg
    13561 gtaaatggtg aagtaacgca tttcttctgt gatcacggtt tttttgtctt cttgtagcca
    13621 gatttttaaa taattttctt cgatcagatt atttaatctc ttttggaatt ggatatctcc
    13681 gtggttgata acgaataact tgtacacgaa cgtatttgta tagacatagt cgatcaaatg
    13741 agcgtataga tcctcgtagc tgtgtgtcgt gtcataggaa atgatttcat ccaagtctta
    13801 gaaaaagcta ttttctagct tttcataaag atcatagata tccgtataat gtttataaaa
    13861 tgtcgaacgg tgaagatcag cagtttcggt cagttcacgg atagtgatgt tttgaatttt
    13921 tcgcgaattg taaaattaag ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt
    13981 atttccgacg aaagaaaaca aaggagtgta accataaatg acctaca
//
LOCUS       DAIGQM010000068        13946 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.070, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000068 DAIGQM010000000
VERSION     DAIGQM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.070"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            136..309
                     /locus_tag="NOA48_002210"
     CDS             136..309
                     /locus_tag="NOA48_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790448.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="NOA48_002211"
     CDS             949..1422
                     /locus_tag="NOA48_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCI0790449.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="NOA48_002212"
     CDS             1431..1658
                     /locus_tag="NOA48_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790450.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="NOA48_002213"
     CDS             2294..2665
                     /locus_tag="NOA48_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790451.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="NOA48_002214"
     CDS             complement(2921..3163)
                     /locus_tag="NOA48_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0790452.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="NOA48_002215"
     CDS             complement(3195..4097)
                     /locus_tag="NOA48_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0790453.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="NOA48_002216"
     CDS             complement(4110..4298)
                     /locus_tag="NOA48_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0790454.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="NOA48_002217"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="NOA48_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0790455.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="NOA48_002218"
     CDS             complement(4913..5806)
                     /locus_tag="NOA48_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0790456.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="NOA48_002219"
     CDS             complement(5884..6807)
                     /locus_tag="NOA48_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0790457.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="NOA48_002220"
     CDS             complement(6856..7206)
                     /locus_tag="NOA48_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0790458.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="NOA48_002221"
     CDS             complement(7239..8141)
                     /locus_tag="NOA48_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0790459.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="NOA48_002222"
     CDS             complement(8134..8991)
                     /locus_tag="NOA48_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0790460.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="NOA48_002223"
     CDS             9325..10134
                     /locus_tag="NOA48_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0790461.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="NOA48_002224"
     CDS             10174..10671
                     /locus_tag="NOA48_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0790462.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="NOA48_002225"
     tRNA            complement(11056..11129)
                     /locus_tag="NOA48_002225"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="NOA48_002226"
     CDS             11316..11639
                     /locus_tag="NOA48_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790463.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="NOA48_002227"
     CDS             11803..12057
                     /locus_tag="NOA48_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790464.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="NOA48_002228"
     CDS             12127..12372
                     /locus_tag="NOA48_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790465.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="NOA48_002229"
     CDS             12448..12813
                     /locus_tag="NOA48_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790466.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="NOA48_002230"
     CDS             complement(12874..13437)
                     /locus_tag="NOA48_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790467.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4089 a         2577 c         2304 g         4976 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaat
//
LOCUS       DAIGQM010000069        13924 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.071, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000069 DAIGQM010000000
VERSION     DAIGQM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.071"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            79..2008
                     /locus_tag="NOA48_002231"
                     /pseudo
     CDS             79..2008
                     /locus_tag="NOA48_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            2134..2688
                     /locus_tag="NOA48_002232"
     CDS             2134..2688
                     /locus_tag="NOA48_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCI0790468.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQFFVLYAVEYRKMFQRK"
     gene            complement(3418..3732)
                     /locus_tag="NOA48_002233"
     CDS             complement(3418..3732)
                     /locus_tag="NOA48_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCI0790469.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(3746..4006)
                     /locus_tag="NOA48_002234"
     CDS             complement(3746..4006)
                     /locus_tag="NOA48_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCI0790470.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            4176..4490
                     /locus_tag="NOA48_002235"
     CDS             4176..4490
                     /locus_tag="NOA48_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0790471.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4492..6147
                     /locus_tag="NOA48_002236"
     CDS             4492..6147
                     /locus_tag="NOA48_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0790472.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            6230..8365
                     /locus_tag="NOA48_002237"
     CDS             6230..8365
                     /locus_tag="NOA48_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0790473.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            8540..9049
                     /locus_tag="NOA48_002238"
     CDS             8540..9049
                     /locus_tag="NOA48_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790474.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            9046..10350
                     /locus_tag="NOA48_002239"
     CDS             9046..10350
                     /locus_tag="NOA48_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0790475.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            10446..11315
                     /locus_tag="NOA48_002240"
     CDS             10446..11315
                     /locus_tag="NOA48_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0790476.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(11427..11747)
                     /locus_tag="NOA48_002241"
     CDS             complement(11427..11747)
                     /locus_tag="NOA48_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCI0790477.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            11850..12296
                     /gene="dhaM"
                     /locus_tag="NOA48_002242"
     CDS             11850..12296
                     /gene="dhaM"
                     /locus_tag="NOA48_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCI0790478.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            12271..13281
                     /gene="dhaK"
                     /locus_tag="NOA48_002243"
     CDS             12271..13281
                     /gene="dhaK"
                     /locus_tag="NOA48_002243"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCI0790479.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            13309..13914
                     /gene="dhaL"
                     /locus_tag="NOA48_002244"
     CDS             13309..13914
                     /gene="dhaL"
                     /locus_tag="NOA48_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCI0790480.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
BASE COUNT         4664 a         2445 c         2956 g         3859 t
ORIGIN      
        1 gctgtgttct atccttttat ttatctctag gcccttattt attttgggac aggtatctct
       61 tcaagaaaag gagagaatat ggacaacgaa atgattagtc aattacaatt tgatcggatc
      121 aaaaaggaaa tccaagcaag agcaattgga aactatagca aaaaacgaat cagcgatatg
      181 acggtctcga caaacctaca aactgtcttg gatcgtcaag aagaaacaag agaagcacgc
      241 ttgatcttag aaagcagtca gcatgttcca tttatggggt tgccgaggat cgatgcactg
      301 acagaacaag tcaaaaaagg gttgattctg cagccaactg atttgatcga atatgcggat
      361 tttcttagaa gcagtcggat gatcacaaag ttttttgata agaatcaata ccagacaccc
      421 ttgttgtttg cttatagcaa acatcttcct gatttgataa atgtagaaga gttgattgac
      481 cagaaaataa aaaataataa agtcagtgac gacgcgtcac gtaatttgcg taaagtacgc
      541 aaacaattac aactaatcga aaaagaaatc cagtcaaaat tactgaaatt cttgcgtcat
      601 ccgaaaaaca aagaaatgat ccaagaagca atgattgttc aaaaaggcga atactatacg
      661 attcctatca aagccagcta taaaaataaa atagatggaa cgattatcga tgaatcaaat
      721 aaaagaacga cggtttttat tgaaccaact gtgatttcta aattgaatga acactatcag
      781 ttgttaaaag ctgaagaaat cagtgaagaa tatcaagtcc tggcggcatt gactggtgct
      841 atcgcagaaa acgaagaagt gatcgattta ttgatcgaaa cgatcacggt gttagatatc
      901 atctttgctc gggcaaaatt tagccgagaa atcaatggaa gcacacctag aatcaataaa
      961 tcggaacata tcattatcaa gcaaggcaga catccatttt tacctgagca tgcggtacca
     1021 ttggatgttg aaatcggtaa agactatcga ggcttgatta tcaccggagc aaatgccgga
     1081 ggcaaaacag tcgtgttgaa gacagtcggt ttattgactt tgatggcgat gttcggtatg
     1141 caagttccgg caaaagaagg gacagagctt gctgtctttg atgagatttt cgtcgatgtc
     1201 ggtgaccacc aaaatttaga aaatgcgttg agtacatttt ctggtcatat gcaaaacatc
     1261 gctgctattt tgaaaaagat aaaaaggaat acgttggtac ttttagatga gattggcagt
     1321 ggaacagagc caaatgaagg ggctgcacta gcgatcgcaa tcatggaatc tatgtatgag
     1381 caaggggcat tgatcattgc cacgacccat tatggagaaa tcaagaaatt cgccggagat
     1441 catgaagatt ttgtgccggc tgctatggct ttcgatcggg aagcacttcg tcctaaatat
     1501 cagttgcggg ttggaagaaa caggagaaag ccaagctttg tggattgctc ataaaatgga
     1561 tatgtcgatg aaattgatcc atcaagcaga gcgttacttg gcggaaaaag cctatcggac
     1621 acagaaaaaa gaatttcttc ctaagacagc agttacaaat aggaaggaga ataaaaaaga
     1681 acgtcagctc tttgcaaaag gtgatcggat atttgtcaat gaataccaaa aagaagcgtt
     1741 agtttatgaa gatataggtg aagatacgat tgatgtatat ttagacaaaa aaataatcca
     1801 cgtgcctcgt cagcgtgttc gtctggtgcg ttcagcagaa gatctgtacc cgacaggtta
     1861 cgatttagac agtctgttta tcgattataa aacacgtaaa cggcagcgtg acctagagcg
     1921 aggatcaaaa aaagctcata aagtactagt aaaagaaatg cgcaaacgac aggaagaaag
     1981 aagagtaaac gatgaaaaca gcaagtgatt atctcaaatt agctcataat atcagtgtct
     2041 gtaaagaaaa ataaaaacag tgaaatcatt ggttttattc cccgtgtaag ctaaaataaa
     2101 aagaaaagag tgctgaggag gtagggcgat aaaatgaaat taagcacaga ctggcgtaaa
     2161 gaaatacaaa cgattccgaa tcttttatcg atattccgta tttttttgct gccgatttat
     2221 ctttattttg tgctgagaca gtcattttat atagcaggag cggtcattgt tgtctcaggt
     2281 ttgtctgatt atctagacgg ggtcattgct cggagatata atcaggtaac agacttaggg
     2341 aaggtgcttg atccgtttgc agataaattg acacaacttt ttctgatttt gtctatggca
     2401 tggtatcgac cgtggctttg gctgttgttt ggtctattct tgataaaaga aggctttatg
     2461 tttgtagctg gattaatcgg gctatctaaa aatatcaaat taagtggagc gaagtggtat
     2521 ggcaaagtag cgactgctgt catctatgtt ggcatgatcc ttttgctgct tttcccagaa
     2581 ttaccaacgc tgtgggtgag agtcattttt gccgtcatca cttacggtct tttacaattt
     2641 tttgtcttgt atgctgtcga gtaccgaaag atgtttcaaa gaaaataaaa aaggggtgtg
     2701 acctatgtcg cattcctttt tttgataaat agactcccag tagctacttc tcgataataa
     2761 gccaaccgaa ccaaaaacag gagaagttgt ttttgaaatt atttcttgtg attcggagtt
     2821 aaatggtagg ctcacaacct cttggtaaac ggtgttcaat cagctgacct tcggtattag
     2881 ctcaaaaaac ggcaaaatat gagcagctat ttttccgttt gtttctctaa tactcaggtc
     2941 aaaccgctga ttttacaacc tcttccttaa acggtattca aaagccagtt tctcggtatt
     3001 aagccaaatt tatgcaaaaa tgtagaaatc cattttcaca aaatttttct taatactcga
     3061 aactaagcga ctttttcaca atctcttcct taaacggtgt tcaatcagct gaccttcggt
     3121 attagctcaa aaaacggcaa aatatgagga gctattttcc cgtttttttc tctaatactt
     3181 aggtcaaacc gctgatttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc
     3241 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatt
     3301 acttgatgca ggacagcgtt ttcacaacct ttgattcacg gttttccaga agtagcttct
     3361 tcgaaaaata agccgaaatt tcttgaagct gatcacttct gtcgcaacct ctactgacta
     3421 aggcttgata taagcataac cttgggattg cagttcaact aaatcaagga cacctgctgg
     3481 tacaacgatt acttgttcag gtaaagaact ttctgaaata tgattagcac gcatagcatt
     3541 ggcgcaagcg tgaaaaacga ctccttgcaa atctaagaat tctgcattgg cagagtctag
     3601 ataaccggta atcgcgatgc catttacaga tacgacaatc gtcgtttctg gagaagcttt
     3661 tatcaggttt tttacgtttt tccctgtttc tgaccatttt tctaattcat caatatggaa
     3721 aacgactttc attgaaatca ttcctttact ttttaataat catcttgatc gcttgttcta
     3781 gtttagccgc ttgttcttct ggattactat caggtttctc aaagcaattt ttcagattat
     3841 ctgcaacgat catgcccatt acgcgatcaa tactagaacg aacagcgctt aattgagtga
     3901 tgacatccat acattctttt tcgtcttcga tcattttttg gataccacga atttgtccct
     3961 ctgtacgttt caaacggttc aggatatttt tattatcaat ctccataaca cattctcctc
     4021 tatttttata attagataat accccttatc ggtattttat gcaaatataa aaagtagtga
     4081 aaaaaatgaa gagtcattct ggttgacata ttaataaagc tcctgtttaa tataccccat
     4141 gaggtattta taaaaatgta aatgaggtgc agaaaatgaa tttgctattt caatcaataa
     4201 aatcgataac agtcccagaa ttaaaggaaa agcttttgga aaatccagcg ttacttgatg
     4261 ttagaacacc tgcagaatac cggggcgggc atataaaagg agctaaaaat gttccattac
     4321 aaagtataaa cagatatgat ggagacaaag aaaagaccgt ctatgtgatt tgtcaatcag
     4381 ggatgaggag taaacaagca gctaaagaat taaagaaatc tggttatgat gtagtgaatg
     4441 tacgtggtgg catgaatcaa tggtttgatc gaacagtagg agggaaataa gatgaaaatc
     4501 gttattgtcg gaggtgtagc aggtggaatg tctgctgcta cacggcttcg ccgattaatg
     4561 gaagatgcag aaatcgttgt ttttgaaaaa ggaccgtatg tttcttttgc aaattgcggc
     4621 ttgccttatt atctttcggg agaaatcagt gaacgggaaa atcttcttgt ccaaacgcca
     4681 gaatcattat ccgctcgttt ttgtttagat gtgcgtccaa atcatgaagt gacagccatc
     4741 tttcccgaaa acaaaacggt agaagtcgta catgagggtc aaaaacacat tgaacagtac
     4801 gatgcattgg ttttatctcc tggtgcaaaa ccagttgttc catcgattcc agggataaca
     4861 gaagccgaca atgttttttc tattagaaat gtaccagata tcgataaagt gatgcatgca
     4921 ttagaaaaac agccaaagcg tgccgtgatc gttggtgcag gattcatcgg attggaaatg
     4981 gcagaaaacc taaaaagaag aggtttagaa gtcatggtga tcgaacaagc accacatatt
     5041 cttccaacac tggatgaaga aatggcagct tttatagaaa aagaattgtc tcatcaagga
     5101 gtagaagtga ttacttctca tgctgtcgct ggatttgaag accacgggaa acgattgcga
     5161 ctggatgatg ggcgtaccat ccctgctgat ttagttattt tatccattgg tgttcgtcct
     5221 gataaccagc tagcagtgac cgctggaatc gaattaggca tacgcggggg tatcctagta
     5281 gacgaacgtt atcaaacgaa tattcctgat atttatgcgg tgggggatgc tatcgttgta
     5341 aaacagcaaa tcactggaaa agatgcactt atttctcttg cttcaccagc caatcgtcaa
     5401 ggtagacaag ttgcggacac gatttccgga atttctcgaa gaaatcaagg cggtattgga
     5461 acagcaatta tacgaacgtt tggaatgact gccgcatcca ccggtttaag tgaaagaaca
     5521 gccaaagaaa acgaactgtc ttttgaagtc attcatgtat caggaaaaga tcatgcaagc
     5581 tattatccag aagcaacaga tattttactg aagttgatct tccatccaga gactggcgag
     5641 atttatggtg cacaaggtgt tggggcaaaa ggtgtggata aacggatcga tattttagca
     5701 acagcaatca aagggcattt gacgatcttc gatttaccgg aattagaatt gacgtatgca
     5761 ccgccatttg gctcagccaa agatccagta aacatgctag gatatgcagc aatgaacatt
     5821 gcagaagggc ttagtgaaac cgtacaatgg catgaattgc cgacagaact agcaaaagga
     5881 aaaattttat tagatgtgcg aacagcagaa gaattggaaa agggcaaatt caaggaagcc
     5941 aaacatatcc ctttgaatga acttcgggac cgattaaatg aattagacag ccaacaagaa
     6001 tatatcgtca gctgtcatag cggattacgt agctatctag cggaaagaat cttgaagcag
     6061 tctggctacc acgtaaaaaa ccttgatggt gcattttctt tatatcaaac tgtccgacct
     6121 gaagaactga tatatcctaa caaatgatac tcgttaaaaa gcttgcattc gactcttaaa
     6181 agaggtaaac taatcggttc caccacttta aaaaaagagg agaatgtgta tggtcaacac
     6241 acaaaaacag ttagaagaag catatctgaa gaacgtgtat caaaagctaa ttgataaaaa
     6301 aaacgaactg cgggaatcga tggatacggc aaaaatagaa ggaaaccagt cgttgaaaga
     6361 aatggctggc gagcttcgat tgaattttga cagttactta gataacctgg atactttttc
     6421 gatgattgaa atgaaaaata gagaaatcga tcagatgaat atcaaacaga aaaacgcaga
     6481 aaatcagcta gcaaagatcg aacgtttatt gaaaagtccc tactttggaa aagtcgttgt
     6541 agactttctg gataatgagc caaaagaatc cttttatatc ggtacagcaa atttcacaga
     6601 tgatgcagat gaaaatcttg tttatgattg gcgttcacca attgccgaac ttttttacaa
     6661 taacatgatt ggtccatctt cttatacggt tcgtcaaaat aaaatcgata cggttattaa
     6721 agaaagacga caatttcttt tggaaagaga tcgtttggtc aagttttttg atacgtctgt
     6781 agctattcaa gatgacgtat tattagaagt cttaggccaa gatgagacca atgaaatgaa
     6841 ggctatcact gctacgatcc aatcggaaca aaacacaatc attcgggatg tgaaaagtca
     6901 aaatatcttg gtaaatggcg tagcaggaag tggtaaaacc tctgctatca tgcagcgtat
     6961 tgcgtatctg ctctatttat atcgagatac gatgacatcc gatgacttgc tgattctatc
     7021 acctaatcat cggtttatcg actatatttc gaatgtccta ccatcattag gtgaaagaaa
     7081 tccactgaat ctaaccatca tacagctggt ttcacagctt tcagcagagg aaatagaagg
     7141 tgaagaggct tatttcaaac gtatcacggg agaaaatgta tcggagcaga cagaacgttt
     7201 gcgtagcaaa aagtttatcg ataatctaaa acaatcagat cctttgtttt tagatcatcc
     7261 gaattttatc cgtggactta ctaaaaatgg aaaaacagtc ctttctaaaa aaacgatcga
     7321 aaaaatatat gagaaagttc ctgctcatcc taaattgatc gataggcttc aagcaacgaa
     7381 aaaggcactg atgagcgaat ggaagaatca tcttttgaaa caagcaaaaa gtcctgctgt
     7441 gcagaatcag gtactctcgt tgacagaaga taggcagttg gaattattcg gtaaattgat
     7501 ttctgatgat tcggaacaaa gtattgtagc ttatgcaagg aaacttttac aaaaaaaata
     7561 tcgaaaaata accagacaaa tcgaagaaat ggcatgggtg gatgagcatc agttgtttga
     7621 aagaatttat gaaaaacgat atggctcagc ttatgcttgg caacccacac gtactgttga
     7681 tgaagcagtc attatattag ctattcgtca tttacttgtt gaaaaggtaa atgtaccagc
     7741 atttcgctat ctattgattg atgaagtaca agattatacc ctggcacaat taggtctatt
     7801 gatcgaatta tttccaaaaa ctcactttac tttagtaggt gacgagaatc aggcaatctt
     7861 taattcttcc actacttttg ctgatattat gcgttgtttc gacgactacc atctgccgat
     7921 ccatcggtat gatcttagaa atagttaccg ttctagcgga gcaatcacag agcttttcaa
     7981 aacctatgct gtggatcaag agaagatcga catcgtatcg atccgaccgc aaggaaaaga
     8041 acccgaatac cgctcttttc gatcctctga agaattgttg aaaatactag ctgagatttt
     8101 ggtttctcta aaaggagaaa aagcggcagt tatcacccaa acagaagagg aaacccaaac
     8161 gctacaagaa tcgattaaaa aaaattcata tggattagaa aactgccaaa tcattccttt
     8221 gagtctagca aaaggactgg aatttgatca tgtaatctta tatccatttg aaaacgatgg
     8281 agatgagcaa agaagacgca gacaaatgta cacggcgata tctagaggaa tgaaaagcat
     8341 tgtcgtattg gaaagagcaa cataattaag agataaaaaa taaaaagaac aactgataaa
     8401 aagaacaaaa tatttttcat ttgctgatga gaaatgtttt gttctttttc ttaggaaaaa
     8461 tttaggaaca ctttatgtga aaagaaatga aatgtatggt aaactcctac gtcgtaacaa
     8521 aaaaacgtga ggtgaggata tgaaaaaagt aacaagagaa gaagttgcat caattttggt
     8581 gaaagataag tatttttcaa aaggtaatta ctggttaaag atttggcaaa cgttagtggc
     8641 tcttttagga tggatgatcg ttgttcttcc ttttatatgg gtctttttcc cattaacgag
     8701 accagaaaga gccaaggatt tttccttgta cgctttttta tcagaaaaga aaatgctgta
     8761 tttcttaatc ggcttttttg tattgatttt tttcagtttc ctgattacct catttgtatt
     8821 gactaggtgg aacaatcgaa atctatacaa aaaagtaaat aaatcttttg aatatgaaga
     8881 tgaaaaattg aaaaaaagac aagaattact tgaagaagtg tatacggaac gttttggaac
     8941 aaaagaagag agagaaacgg tccgttttta ttctgtctcc gaagagaaaa atctagatac
     9001 gacattcatt gcagatttgt ataaagaaaa tggggtggaa ctgaaatgat ctcaatcacc
     9061 catacaggta atttattctt agatacttgt ttgtctatta tgtatttttt tctcgtttct
     9121 tatccgattt taggcggatt tgtatggttt attggtgtct ggtgttatgt gtttttatac
     9181 aaacataagc aaaaagaatg ggtagatgtt cccttgagtg tcgaaccgtt catcacgatc
     9241 atggtgccag cccataatga agaaattgtg atcgaatata caatcgagta tttgatgacg
     9301 aaattgaatt atcacaacta tgaggtatta gtgacagacg atggttcaac ggaccaaaca
     9361 ccagaaatat tagctagact gatgaaaaaa tacgctaatc ttcgtgtggt tcggatcgaa
     9421 aaaaataaag gaaaagccca cgcgtttaat atcggacttg cctttgcaaa agggaaattg
     9481 attttaagca atgatgcaga cacggtaccg gagccagatg cactgattag gtatgtgaat
     9541 tatttcattc gccctggtgc aagacatatt gctgcggtca ctgcaaatat ggatgtccaa
     9601 aatcgtacca aattgattgc aaaatctcaa acggttgaat tctcaagtat cgtgggcatc
     9661 attaaacgaa cacagtcagc tgttttcggt ggtctttatg cgtacagtgg agcaaatacg
     9721 atgtatcgaa aagaagcctt gatcgatgtg ggcggattca gacaagatcg agcgacagaa
     9781 gacatcagta ttgcttggga tcatcagtta aatgactggt tatctgtttt tgctcctgag
     9841 attatctttt tcatggaagt acctgtgacg ttgaagatgc tatatcgaca cagaaaacgt
     9901 tgggcaaaag gtggaacaga agtctggctg acgaatttca aaaaagtgat gctccatcct
     9961 tttaaacata ttggaagaac gatcatcttc attgatcaaa cattgagtat tgtctggtca
    10021 atattctttt gtatttccgt agttcttttt gctggattaa tcgggcatta tgtatatcaa
    10081 ggaaactacg aacagattta tattactttt acattcagtt ttgtgttcat ctgctttgaa
    10141 atggtcgcag gatttttcca gttgctagct tcgctgattg tagatgatcg acgaagaaaa
    10201 ttgaaatacc ttcttttcgc accactatat atgcttttgt tctggatagt gaacgcgata
    10261 acgatcgtga cgactttcat tccagcagtc aaaacgattt taggttatgg aagcgggaca
    10321 tggaaaagcc cggaacgtac aaaaaaataa aagatgcacc gttttttaga caaacagcct
    10381 gttgtgttta tggttcttcc aaacattttt gcttataata agaaattagt taaaaagtag
    10441 taaggatggg aaaagtgatg aaaaaaagaa tgaagccgtt aatctggcca attgctgttt
    10501 ccagtatttt cttattggga cagacagctt ttgcggaaac ttctgaacct gctcaaacag
    10561 aaccttcaac aaccataagc tcttctggtg ctgaaaacgg tgcctcggaa acagaaatga
    10621 cttccaatgt accgacagat aattcaggag aaacgatttc atcttcagaa gatacatcaa
    10681 taaatagttc tacctcttct gaccaaatcg atcatttgca agacttggaa aataaaagaa
    10741 aagaactcga agaagcatta gaagctgcaa aaaacaaatt gaaagaagac caagcagcaa
    10801 tcgatcaaga tttagctgat cttaaaaata aagtgggaaa tgaccgtgca caacttgaga
    10861 aaaagcttgc cgaagcgaaa gcaaaagcgg aagctgtcca aacagatctt gacgggaaga
    10921 tccaacaagc aaaagaattc aatcagcaat taaatcaggt tgctcaaaca gcttctggaa
    10981 agctaagtca aactcaagcg gatatcacag cggccagtca agcaatccac ggaaagatca
    11041 gcgaagcaca aacagttgct aatgattttg aagcaaaaaa agctgactta gcagctagtt
    11101 tccaacgaat aaaagatatt ttgcattcgg caggagaaaa atcagtgacc tctggaagca
    11161 cgacagaaac agttcagcaa acgacagagc catccaaatc aacaagtcag actttgccaa
    11221 aaacaaatga aaaaacagct tctgtcagtt attccttagc aggggcgggt gtgttagtcg
    11281 cagcagctta cggaatcatc cgcaaaaaga aataaaaaag agaggatggg aaggtagagt
    11341 acctcgaagt tagactgaaa aatctaattc ttgagtgcca ctacatgtcc catctctctt
    11401 tagttattaa aacagatgtc ccctacttat ctcgtggaga cagctgttcc actacatgtg
    11461 accatcagca tgccattgtc gctgcctaat acttcatagt ccatttttac gccaatgatc
    11521 gcatcagctc ctaatgcttt tgcacgttcg gccatttcgg caagtgcttc ttctcttgca
    11581 cccattagtt cgttttcata gctttttgag cggccgccaa agatatttcg caaccccgcc
    11641 tccaagtctt taaatgcatg gatcccagta atgacctcac caaaaacgat ccctttataa
    11701 gctactacgg cttttccctc tacactgttc gttgttgttg taatcattcg atcactcctc
    11761 tcttttaatt aaagtataac aaacttcaag aagcactaca catattttcc caaaattaga
    11821 aatttattat atacttgaat tgttcattaa tgaaagcgaa accaatcgtt agcaactatg
    11881 taaaagaaag gaagattctt gtgaaaaaaa gtattttgct tatttctcat agtcaaaaag
    11941 taacagatgg tattaaagaa atgattgagc agatgcaaaa atccgaagag gtgcaaattt
    12001 tttctctcgg cggaataaat ggcgagatcg gatcagaccc gatgaaaatc gtagaagcag
    12061 tcaatgaatc aagcgatgca gctagttatt ttgtttttgc ggatatcggt agcgcggtat
    12121 tgaactcgga actggcaaaa gacatgttgg aagaagagca gcagcaacgt tatcatctgg
    12181 tggatgcgcc tttagtggaa ggagcttttg cagcagccat cactgccggt ataacagatg
    12241 atactcagca aatcttaaca gaagcacaaa atgccggaaa gaaaggatgg gaataaattg
    12301 aaaaaaatca tgaatgatcc aagcaatatt gtcgaagaaa tgctggaagg attagtaaaa
    12361 agctatccag aacttgttca tcgtgtagaa tcttcccgtg ttgtagccaa gaatcagaaa
    12421 gcggaacaag ttggtttggt ttctggtgga ggaagcggac atgaaccatc ccatgccggg
    12481 tttgtagggg aagggatgtt aagtgcagcg gtgcttggtg atgtgtttac ttctccaact
    12541 ccagatcaga ttcagacggc tattaaggaa gccgatagtg gaaaaggagt tttgctgatc
    12601 gttaagaatt atacagggga tgcattgaac ttcgatatgg caaaggaatt agctgctatg
    12661 gacgatattg aagtagaaag tgtgatcgta gatgatgata tcgccgttga aaatagtacg
    12721 tatactgctg gaaaacgcgg agttgcaggt actgtccttg tacacaaaat cgtgggcgat
    12781 gcagcaagaa acggtgcttc cctagctgag ttgaaagaac tgggagaaaa ggtcgtacag
    12841 gcaactaaga cgatcggtct agcgcttcga gcagcaactg taccagaagt agggaaacca
    12901 ggattcgaac taggagaaga tgagatcgag tatggtgttg gtatccacgg tgagccaggc
    12961 tatcgtcgag aaaagatgca gccttctaaa gtactggcaa aggaacttgt tactaagatt
    13021 ttagatgatt actcgaattt accaaaagaa gcaggtgtac tagtcaacgg aatgggcggg
    13081 acgcctttga tggaacagtt cgtgttcatg aatgatgttt tagctctgtt ggaagaaaga
    13141 ggcgtcaatg tagttttccg aaaagtcggt aattttatga cctcactaga tatgcaaggt
    13201 ctttctctaa cactgatcga cttgacggag acacaatgga aagattcttt agaaagcaat
    13261 gtacagacga tttcatggta aaaaatctca agataaaagg gtgataatat gaaactaacc
    13321 gttcaagaaa tccaagaatg gctcacgcaa tttgcagagg caatcaatca gaacaaacaa
    13381 tatctcagtg atctagatac cccgattggc gatggagacc atggaaataa catgggaaga
    13441 ggggtttcag cttatgaaga agcttttcaa gccgatcatc ctgaaacaat cagcgataca
    13501 ttcaaagtat tctctatggc gatgatatcg aaagtcggtg gggcttctgg tccgttatac
    13561 ggatctgcat tcatgaacat gatgaaagcg acaaaagagg tcgattctat tgattctcaa
    13621 gaaaaattag gcgaagtgat cgagcaggga acagcgggta ttcaaagccg aggaaaggca
    13681 gaagctgacg ataaaacgat gttagatgtt tggctgccag tcacagaggc attgaaggca
    13741 gggaatttaa caaaagaaat cattgaccag gcaaaagaac acaccaaagt cttggtagct
    13801 aaaaaaggac gagcttccta tctaggagag cgtgcaatcg gacatatcga cccaggagct
    13861 gcttctagtg ccattttatt ttcaacgctt ttagatgtga tcaatcaacc ttaagttcaa
    13921 taaa
//
LOCUS       DAIGQM010000070        13694 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.072, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000070 DAIGQM010000000
VERSION     DAIGQM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.072"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..903)
                     /locus_tag="NOA48_002245"
     CDS             complement(<1..903)
                     /locus_tag="NOA48_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCI0790481.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSES"
     regulatory      complement(927..971)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1186..2154
                     /locus_tag="NOA48_002246"
     CDS             1186..2154
                     /locus_tag="NOA48_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0790482.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2267..2545
                     /locus_tag="NOA48_002247"
     CDS             2267..2545
                     /locus_tag="NOA48_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0790483.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2663..2899
                     /gene="secG"
                     /locus_tag="NOA48_002248"
     CDS             2663..2899
                     /gene="secG"
                     /locus_tag="NOA48_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCI0790484.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3002..3757
                     /locus_tag="NOA48_002249"
     CDS             3002..3757
                     /locus_tag="NOA48_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0790485.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3760..6117
                     /gene="rnr"
                     /locus_tag="NOA48_002250"
     CDS             3760..6117
                     /gene="rnr"
                     /locus_tag="NOA48_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCI0790486.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6139..6603
                     /gene="smpB"
                     /locus_tag="NOA48_002251"
     CDS             6139..6603
                     /gene="smpB"
                     /locus_tag="NOA48_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCI0790487.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6905..7624
                     /gene="atpB"
                     /locus_tag="NOA48_002252"
     CDS             6905..7624
                     /gene="atpB"
                     /locus_tag="NOA48_002252"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCI0790488.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7677..7892
                     /gene="atpE"
                     /locus_tag="NOA48_002253"
     CDS             7677..7892
                     /gene="atpE"
                     /locus_tag="NOA48_002253"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCI0790489.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7983..8507
                     /gene="atpF"
                     /locus_tag="NOA48_002254"
     CDS             7983..8507
                     /gene="atpF"
                     /locus_tag="NOA48_002254"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCI0790490.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8494..9036
                     /locus_tag="NOA48_002255"
     CDS             8494..9036
                     /locus_tag="NOA48_002255"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCI0790491.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9059..10615
                     /locus_tag="NOA48_002256"
     CDS             9059..10615
                     /locus_tag="NOA48_002256"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCI0790492.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10629..11531
                     /locus_tag="NOA48_002257"
     CDS             10629..11531
                     /locus_tag="NOA48_002257"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCI0790493.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11554..12960
                     /gene="atpD"
                     /locus_tag="NOA48_002258"
     CDS             11554..12960
                     /gene="atpD"
                     /locus_tag="NOA48_002258"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCI0790494.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12974..13396
                     /locus_tag="NOA48_002259"
     CDS             12974..13396
                     /locus_tag="NOA48_002259"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCI0790495.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4527 a         2449 c         2986 g         3732 t
ORIGIN      
        1 actttcggaa aaaagacgag tatctacttt tgtcataatt ttactgttag caggtttctg
       61 ccaaaattca taacgatcaa ccaatgtttg tccacgactt attccctgag tttccacagc
      121 ggtgaagctt ttgaaacctt cacagatggc cccctcgatg aaataagcaa cagctaacgg
      181 atcattgatg acacatccta aaattctttc ttgtttccag tggaagtcaa aataaaaacg
      241 agtgatcgct tttaaatact ctccctcttc aggattcatt tgacagcagt attcgaggat
      301 agtcggtgtc aagacgattt ctcttgtcac atctaaccca accatttcta tcgtttgttt
      361 gagattctcg aatacataag aagctgcttc aggatcacac cagtaattgt attcagcaac
      421 tggcgaacag ttaccatggc ttttgtaagt tccacccatc gagacaaaac gatccatatg
      481 tttcccaata tttgggttga ctttcaaagc aaaagcgata ttggtcaaag gacccaaagc
      541 aatgactgat gtatttgtct tttctttgaa ataatcagcc aaaaaatcaa cggcatggag
      601 aggttctgcc tgttttctca agatcatcgg gaaatttgtt tcccctaaac catccatacc
      661 atgagtgtct tgtgcactga tgaaaggttg cttcaaaggt ttttccattc cttgataaac
      721 aggaatgtct aaacgatcac agcgttccag gcatttcagc acattctgcg tacctatatc
      781 tgcagggaca ttcccacaaa ctacggtaat agcaactact tcgatatcag gggatttgac
      841 agctaatgat aaagctaaag tgtcgtcgat ccctggatcg caatcaataa ttacttttcg
      901 cattatttcc aatctccttt ctttagagat acttagtttt ttattctggg aagtttccga
      961 accagtccaa gacgagcgtc ttgattataa tgcacgaaat tagtatactg gcttttattg
     1021 cgaatgtaaa tgctctctta caagtaaatc tattgaggag aactttaagt aaatgataca
     1081 atgaaaaaga aatggaattt acgtgtgccg aaaataaaga atcctatgga tcggtacatt
     1141 ggataataga tagattatag tttggcagaa agcggcgggt gtacaatggt tattttttat
     1201 ttcattctta ttctgataat tatagggatc agttaccatt ttctttctta tttttatgca
     1261 aagaaattag taagagcggg agtacagaga ggatatgact ggtatgaaga cactggtcat
     1321 cgtttgatgg accctgctgc agtcacgtca gtagaaaaaa aacgacaaaa attagaagaa
     1381 gagtgtgaaa gcttttggga gcagggaaca cccaaaacaa tcaaaagtta tgacgggttg
     1441 aaactagctg gtcagatgtt catccatcca aataagcaga ataaatgggt catttgcgta
     1501 catgattacc gaagcacagg gaaaagagac atgtctcata taggtaaaag atatgcagag
     1561 aaaggattca acgttcttgt acctgattta cgtgcgcacg gagaaagtga aggagaaatc
     1621 atcggaatgg gatggctaga tcggctagat ttaattgcct ggatccaact catcttagat
     1681 gaacagccga atgcgtccat tattttacac ggcggatcaa tgggagcttc tacgatcatg
     1741 atggcaagtg gtgaaaaact tccatcagcg gtcaaaggat ttattttaga cagcggatat
     1801 gtttctgttt atgcagaatt ccgatatatg ttaagtaaaa tcactgtctt tcctaaaaaa
     1861 atggtcatga gatatgcgaa tcattatgcc cagaaatacg ccggttactc cttaaagcaa
     1921 gcatcagcta cgagacagct tggcagcaac catctgcctt tattagtcat ccatggtgaa
     1981 agagatcatt ttgtccctac agaagcagcg tacacgattc aaaatgctac ggcaggggat
     2041 aaagcactgc tgcttgttcc agaagcagaa cacttggaag catcgatgaa agatccgaaa
     2101 acctattgga cagtgatttt ttcatttatt gaacaaagaa taacgatgga ttaattttct
     2161 cttctttttt gtaagtaatt cgaggataaa taattgttta tagatctgga gactgctaaa
     2221 ataaggtagg aataaaaaaa tatcagttat ttgaggagtg cggcatatgg aaatcaaaga
     2281 agaaaaaaat cgtcttgctt tattcaatga tgagcaacaa gagattggag aaatgacatg
     2341 gtcagatgcg ggcccagaca tcatgatcat tgaccataca tttgtagatc cagcatatcg
     2401 tggtcaaaag ttagctgaaa agctagtgta tactggagta gaattagcaa gacgagacgg
     2461 gaaaaagatc attcctttat gcccttatgc aaaaaaagag tttgaaaaga aaccagaata
     2521 tcaagacgtc ttacgtcagt cataagaata acagctgaaa gttttgaact ttcagctgtt
     2581 attccattta tatagagttg tcacggactt ttatctatga taaagttaaa gagacgatat
     2641 cttttgggaa ggaggctgcg atatgtataa tttaattttg ggaatcgtga tcgttttatc
     2701 gattgttatg gtcattgcga ttatgatgca gccaagcaag caaaatagtg cagcgagtgc
     2761 atttaccggc ggtgcggatc aactattcgg caaacaaaaa gctcgcggct ttgaagctgt
     2821 catgcagcga tcaactgcag ttatgggagc tatctggatg atcttattat ttgtcctagc
     2881 atatttatct tcgaagtagt tgaataagcc tctcgcaaaa cggcgggcgg ctttttttat
     2941 tgcaaagaga acgcttaaga agaagttatg aaagaaacta tggtaaaatg aggcgaaaga
     3001 ggtgagacga gtgagacaat taccaaaacc cctttatgca aaacatggaa agcgagcggt
     3061 tttgctgctt cacgcttact caggaagtcc aaacgatgtt cgaatgctcg cacgattttt
     3121 ggaaaaagca gattatacag tttatgcgcc gctttttaaa ggacacggaa caatggagcc
     3181 atatgatatc ttgcaagaaa aagcagaaag ctggtgggca gacactaaaa aagccatcca
     3241 ttttttacag tctgagcagt tttctgatat tgccgtatta ggattatcaa tgggcggcat
     3301 ctttgctgta cgagcactag aagaagaatc agtgattggc ggcggttttt tctgttcgcc
     3361 tttgtctcct gtaaaaacaa acgtgcctga aaactttgaa aaatacgtac gtcaagtgct
     3421 gaagacagca ggtaaatcag agaaagaaat caatgaaaaa gcagttgctt accgctcgtt
     3481 agctgaacaa caattaatgg atatacaaga tcaggcagca atcgtagaaa gtaggttgtc
     3541 agatatccaa cagccgatat ttttagctca agctgggaaa gatgaaatga tcgaccctaa
     3601 tggcgtattt gaaactgcac gcaagttgag ccgtcagcga gtgacacttc aatggtatcc
     3661 tgaaagtggt catgtgatta cagttggtac agcaagacgc gaattagaaa aagacgtctt
     3721 ggaattttta gaaaaattac cttggaatga ggaataaata tgacaaaaga aacgataaaa
     3781 gagaaaattc tctttttcat ggaaagcagt cgcaaacgca gtttttctat ggaagaaatc
     3841 gctgaaggtt tagggttcca aaaaagcgat gattttaaat tactagtaca aacgattgct
     3901 caaatggaaa gagaacagag tatagttttc aataaaaaag gaaaagtgaa acttccttta
     3961 aaaccaatct tgatcgaagg aacatttcga gcaaatgaac gaggatttgg atttgtaacg
     4021 attgatcccg aagaagatga catctatatc ccaaaagaag cgactggttt tgcaatggat
     4081 ggagacaccg tagcaatcga tatcatgaag cgagcaaata cagatatgga tcgcggagca
     4141 gaggggaaag tagtcgagat tcgagaccgg gcgactactc agttagcagg ggaattcgtt
     4201 gcttattcag aagaagaaat acaagaaaca gatctttacg gcgttgttat cccgaaagat
     4261 agaaagctca accaatttaa agtatatgca gcagcagagg gagttcgtcc agttgacgga
     4321 agtattgtgc tgatcgaact gacccattac cctgaaaaag ggtatgcgac tagtttagaa
     4381 gggataatca agcaagtgat tggtcataag aatgaccctg gcatggatat cctctcaatt
     4441 gtcgtggcta atggtatccc tacgaaattt cctgatgatg tattgtctga agcagatgaa
     4501 gttccagatc aaatcagcga aaaggatata actggacgta gagatttaag aaatcagctc
     4561 attgttacga ttgatggaga agatgcaaaa gatctagatg atgcagttac ggttaaaaaa
     4621 ttagataacg gtaattattt tcttggagta cacattgcag atgtttctta ctatgtgaca
     4681 caaggcagtc aattggacag agaagcatat gaaagaggga caagtgtata tttgactgat
     4741 cgagtgattc cgatgatccc gcaacgttta tcgaatggta tctgttcact gaatccccat
     4801 gttccaaggc tgaccatgag ttgcgaaatg gagattgatc caaatggaca agtagtctct
     4861 catgatattt tcccaagtgt gatccaaaca acagaacgga tgacctacac agctgtcaat
     4921 caaatcttag aagatcaaga cgaagaaacg atgcaacgct atgctcagct cgtacctatg
     4981 ttccaagaaa tgggtgaatt gcatcgaatc cttgaaacga tgcgaatcaa acgtggcgcg
     5041 atttcttttg aggatcgcga agcgaaaatc cttgttgatg ctgaaggaca cccaaatgac
     5101 atccagctaa gaagcagagg aattggtgaa cgcttgatcg aatctttcat gcttgcggcc
     5161 aatgaaacgg tagctgaaca ttataataaa ttaaatctgc cgtttattta ccgaatccat
     5221 gaacagccaa aagaagaaaa aatgcagcgc ttctttgatt ttgcttcagc tttgggcatt
     5281 ctggtccgag gaacgaaagg aacgatcaca ccaaaagatt tacagcatgt gatcgaagga
     5341 gtagaagaca aaccagaagc tgcagttatc aatactatgt tgctaagaag catgcaacaa
     5401 gcacgctatt cagaagacaa ttttgggcat tatggcttag cggcagatta ctacacacac
     5461 tttacatctc ctattcgacg ctatcccgat ctaatcgtcc atcgtctgat ccgttcttac
     5521 agtgaagata aaagtgaaag caatcaaagt tcgtgggctg cggaacttcc tgaaattgca
     5581 gatcatagtt ctaagatgga acgtcgtgca gtagaaacag aacgtgaagt agattccatg
     5641 aagaaagcag aattcatgat ggacaaagtg ggagaagaat tcgatgggat catcagctct
     5701 gttgtgaaat tcggcctgtt tatcgaactg ccgaatacag tagaaggatt gatccatatc
     5761 aatgaattga aacaggacta cttccatttt gttgaaaatc atttagctct tgtaggtgaa
     5821 agaactggtc tgacttttaa aatcggacaa aaagtgcgcg taaaagtagt caaagctgat
     5881 ccagatgaac gagcagtgga ttttgaactc gtttccgcag aagaggtcac tgcgttggaa
     5941 cgtccaaaag cacgcaatgg aaaatttgga aaacgagaag gaaaacaagc aggcaaacgc
     6001 tcagaaaaaa atggcaagaa gaacaaacga tatagtgata gtaagcaaac gttcggtaag
     6061 aaaaaaggga aaaagccatt ttacaaagat gtcaaaaaga agaaaaagaa aaaataaaat
     6121 gagttggagg aaacagctat gccaaaaggc gagggaaaac taattgcaca aaacaagaaa
     6181 gctcgccatg attattcgat catcgacacg atggaagcag ggatggtctt gcaaggaacg
     6241 gagatcaagt cgatacgaaa cagccggatc aatctgaaag atggatttat tcgcgtccgc
     6301 aacggggaag ctttcttgca taatgttcat atcagtcctt atgaacaagg aaatattttt
     6361 aatcatgatc cgttgcgcac gagaaagtta ttattacaca agaaacaaat cgttcgtctt
     6421 gaaaacgaat tgaaaaacac tggaatcact gttgttcctt taaaagtcta tattcgtaac
     6481 ggctatgcca aggtattgat tggtctggca aaagggaaaa aatcgtatga taaacgggaa
     6541 gatttgaaac gaaaagatat cgatcgacaa attgatcgaa cattaaaaaa tttctctaga
     6601 taatttcatt atcctttttc gcatattcgg tgcttttgct tttacttaat gataaaattt
     6661 gttagcattt aatctgataa aacatgatta tcacaggttt tttcttagat caggagcacc
     6721 gtgcatgggg aaaaattcgc ttcgtttttg actgaaataa aaaagtgtct aattttcatg
     6781 aaaatgtttt gaattttctg tttcatggtg gtatgatacc gtgtggttag aaaccgattg
     6841 gaaaaaacca gatacgcaca tgaattgatt ttatgtgaat ttcggggaaa agaggtgaaa
     6901 tggattggat gaacgctcgc taacgtttca cattggacca atttggtttg atggtacagt
     6961 ttgtataatg gtgttactga cctgtttgat tgttttcttc ttagcttact tttttacaag
     7021 aaatcttaag ttgaaaccaa caggcaaaca aaatgcgata gaatgggtca ttgattttag
     7081 tcgaggaatc gtaacagata atctgcctag aaaagaattg agcaatttcc atttgttggc
     7141 atttacattg tttttatttg tttttgttgc aaacaacata ggtttagtaa caaaaatcgt
     7201 cttacctaac gaaacaacac tttggaaaag cccgacagca gacccgtttg ttactttaac
     7261 tttggcattt ataatgatct tacttactca cttattcggg gtgaaaaagt taggcttcaa
     7321 aggatatttc gtaaattcgt tcttgaaacc ctatagtttt atgtttccga tgaaactgat
     7381 tgaagaattt acaaatttat taacacttgc tttacgtctt tatgggaata tttatgcggg
     7441 ggaagttttg ctaaccttga ttgcaaaaat gatgacaagc ttaggctggt tctcattacc
     7501 attagcaatt ccattagaga tggtctggat cgcgttctcc ttgtttattg ggagcatcca
     7561 agcatttgtc tttgtcactt tgtcaatggt ttatatgagc cataagattg aagtagaaga
     7621 ataatactcg gttaaaaaac aaactactat ttatctattt taggaggaaa acaattatga
     7681 attatatcgc agcagcaatc gcaatcatgg gagcagcaat cggagccggt tatggtaacg
     7741 gtcaagttat ctctaaaaca atcgaatcaa tggctcgcca acctgaaatg tctggtcaat
     7801 tccgtacaac aatgtttatc ggggtagctc tagttgaagc tgttcctatc ttaggggtag
     7861 ttatcgcctt gattctagtt tttgccgttt aattgaatca gtattaaggc agaaacaaca
     7921 tcgtttgtta ctgctttttt acatggaaac tagaaatact ccaaagaaag gaaggctcgc
     7981 ctatgctgaa tcaattggca attgcagaag ttggcaatgc gatgttaggt aatatcatcg
     8041 ttgtcagcgg ctcatttttg atactactgg ctctcttgaa gcactttgct tggggaccaa
     8101 tcagcgatat tttgaaaaaa cgtgaagaca agatcgccaa tgatttagat tctgcagaac
     8161 aatctcgcat caactcagcg aaaatggaac aagaacgcga acaacaattg ttagcctctc
     8221 gttctgatgc agctgatatc atcaaaaatg cgaaagaaag tggagaatta agccgccaaa
     8281 atattttgaa ggatgctcaa gaagaagcag ctcgtctaaa aagcaaagcc caagctgata
     8341 tcactgtaga acgtgattca gcgctgaact ctgtaaaaga cgacgttgca gaactctctc
     8401 ttcaaatcgc ggaaaaaatc ttgaacaaag aattatctcc agaaatgcat gaatcattaa
     8461 tcaatcaata cattgaaggt ctaggttctt caaatgaaac tagataaata tacagtagga
     8521 agacgttacg ggaaagcttt atttgaactg gcgatcgatt caaatcaagc agaagaaatc
     8581 tatcaagatc tcgtaagttt acgtcaaatc tatgaacaag tacctggatt agggaatatg
     8641 ttaagtgatg ttcgtctaga acctcatgaa aaacgagaaa tcatggacaa gcttgtcagc
     8701 ggttatgatg ggatcgttaa aaacttttta gaagttgttt atgagtataa ccgaatggat
     8761 gaccttttgt tcatgatcga agaatatgaa cgtcgatatg atgaacatca agggttacta
     8821 ttgggaagtg tcacaacagc agtcccactt tcagacgaac aacgaataca attagaaaag
     8881 aatgttgcaa aaacaatgga ctatcaatca gttgaattaa aacaaatcgt tgattcttct
     8941 attattggtg gcgcgattgt tgaagccaac catcgagtaa tcgacggaag cattcgcacg
     9001 caattagaaa aaatgcgtaa tcaattaaac agatagtaca aagaggtagg tgaatcgaat
     9061 ggccatcaaa gcagaagaaa ttagtgcctt gattaaagaa caaattgaaa attatcaaaa
     9121 cgtgctttca gtcgaagaaa tcggtaccgt aacttatgta ggtgacggga tcgctcgtgc
     9181 acatggttta gaaaacgcga tgagtggtga gttgcttgaa ttttcaaacg gctcatacgg
     9241 aatggcgcaa aacttagagt caaatgatgt aggtatcatt atccttggcg atttcgagtc
     9301 cattcgtgaa ggagataaag taaaacgaac aggtaagatc atggaagttc cagttggaga
     9361 ggccttgatc ggtcgggtag tcaatccgct aggtcaacca atcgacggac taggtgaaat
     9421 cgttactgac aaagctcgtc cagtagaagc gatggcacca ggtgttatgc aacgtaaatc
     9481 tgttaacgaa ccaatgcaaa cagggctaaa agcgatcgac gcccttgtgc caatcggacg
     9541 cggacaacgt gaattagtca tcggtgaccg taaaacaggg aaaacttcta ttgcgatcga
     9601 tacgatcatc aaccaaaaag gtcaagatat gatctgtatc tatgtagcaa tcggacaaaa
     9661 agattctaca gttcgtacac aagttgaaac attgaaaaaa tatggcgcaa tggattacac
     9721 aatcgttgtg aatgccggtg cgtctcaacc agcaccattg ctttatatcg caccatatgc
     9781 tggtactgca atgggtgaag aattcatgta caacggtaaa catgtattga tcatttttga
     9841 tgatctttca aaacaagctg ttgcttatcg tgaactttcc ttgctgcttc gccgtccacc
     9901 aggtcgtgaa gcttatccag gggatgtttt ctacttacac tcacgcttat tggaacgtgc
     9961 agcaaaatta agtgatgatt taggtggcgg ttcaatgact gccttaccat ttgttgaaac
    10021 acaagctgga gatatctctg cttatatccc aacaaacgtt atttcgatca ctgatggaca
    10081 aatcttctta gaaagcgact tgttctacgc aggtactcgt ccagcggttg atgccggact
    10141 atctgtatct cgtgtagggg gttctgcgca aatcaaagca atgaaaaaag ttgctgggac
    10201 tttacgtcta gacttagcaa gttaccgtga attagaagca tttacacaat tcggttctga
    10261 cttggatgca gcaacacaag caaaactaaa tcgtggacgc cgtacagtag aaatcttgaa
    10321 acaaaaattg catgcaccgc tagctgttga aaaacaagta gtgattttgt atgctttgac
    10381 acatggattc ttagatagta tccctgtaga cagtatttta gacttcgaac atgaattatt
    10441 cgaatatctg gataccaatc attcagatat ctttgaaaca atccgtacaa caaaagatct
    10501 tccagaagaa gaagcgttga acagtgcgat tcaggaatat aaagacatgt tcttagctac
    10561 aaaaggaaat aattcctcta cagaagataa attgaaatcc attcaaaatg catagtgagg
    10621 tgagatgaat gggtgcttca ttaaatgaaa tcaagacacg tatcgcttca acgaaaaaaa
    10681 cgagccaaat cacgcgggca atgcagatgg tgtctgcttc taagttgaca aaatctgaag
    10741 cttcttcaca gaagtttcag gtttatgcaa caaaagtaag agaaatcgtt acgcatttga
    10801 ctgctactca gttaaatgat attgcctcag aaaatcctag aggggatatc aattacaaca
    10861 gcatgttgct cagccgtcct gttaagaaaa cgggttatat cgtcatcact gcagatggcg
    10921 gtttagtcgg tggatataac agctcgatat tgaaacaaac gatgtctatt ttagaagaag
    10981 accaccaatc acccgatgat tacgtgatga tcgcaattgg cggaactggt gcagacttct
    11041 ttaaagcacg cggtatcaat ctagcatatg agctgcgcaa tctatctgat cagccaagct
    11101 ttgatgaagt ccgcaaaatc gtaaatatgg caacaactat gtaccaaaac gaagtattcg
    11161 atgaattata cgtatgttat aaccatcata tcaattcgct aactagtcag tttcgtgtag
    11221 aaaaaatgct gccaatctca gacttagatc cagaagaagc aactactttc gaacaagaat
    11281 atatttttga accttcaaaa gaagaaatct tgtctcagtt attgcctcag tatgctgaaa
    11341 gtttgatcta cggtgcgatc gttgacgcca aaacagcaga acatgctgct ggtatgacag
    11401 caatgaaaac agcaactgat aatgctgcta atatcattga tgagctgacg gtttcttaca
    11461 accgtgcaag acaaggggct attacccaag aaattaccga aattgttgcc ggagcttcgg
    11521 cactagaata gtattgagat tggaggaaaa aagatgagtt caggcaagat tgttcaagta
    11581 atcggtcccg ttgtcgacgt ggaattttct ttagaccaat ccttaccaga tatcaacaac
    11641 gcattagttg tttataaaaa tgacgaaaat aaatcaaaag ttgttcttga agcagcgtta
    11701 gaattagggg acggagtgat ccggaccatt gcgatggaat caacagatgg tttacaaaga
    11761 ggaatggaag tcattgatac aggcaaagca atctctgttc ctgtaggtaa agaaacatta
    11821 ggtcgcgtat tcaacgtact aggagatacg atcgatttag aaacaccttt cccagaagat
    11881 gcggaaagaa gcgaaattca taaaaaagca ccagcctttg acgaattaag tacaagtaca
    11941 gaaattttgg aaacagggat caaagttatc gatttgcttg ccccatattt aaaaggtggg
    12001 aaagtcggac tattcggtgg tgccggtgtt ggtaaaaccg tactgatcca agaactgatc
    12061 cataatatcg cccaagaaca tggtggtatt tctgtattta ccggtgtagg tgaacgtact
    12121 cgtgaaggta atgacttgta ttatgaaatg aaagattcag gagttatcga aaaaacagcc
    12181 atggtgttcg gacaaatgaa cgaaccacca ggtgcacgta tgcgtgttgc tttgactggt
    12241 ttgacgattg cggaatattt ccgtgatgta gaaggtcaag atgtactgtt gtttatcgac
    12301 aacattttcc gtttcactca agctggatct gaagtatcag ccttgttagg acggatgcct
    12361 tctgcggttg gttatcaacc aacattggca acagaaatgg gtcaattgca agaacgtatc
    12421 acatctacga aaaaaggttc gatcacatcg atccaagcaa tctatgtgcc agccgatgac
    12481 tacactgacc cggcgccggc aacagcattc gcccatttgg atgcgacaac caacttggaa
    12541 cgtaaattaa cagaacaagg gatttatcca gcggtagatc cattggcttc ttcttcaagt
    12601 gctttagcac ctgaaatcgt gggagaagaa cattataaag tagcaacaga agtccaacac
    12661 gtattgcaac gatatcgtga attacaagat atcattgcta tcttaggtat ggatgaatta
    12721 tccgatcaag aaaaagtgtt agtttctcgt gcccgcagag tccaattctt cttgtcacaa
    12781 aactttaacg tggctgaaca atttactggt cttccaggtt catatgtccc tgtagaagaa
    12841 acagtgaaag gattccgcga aatcttggaa ggcaaatacg atgatcttcc tgaagaagct
    12901 ttccgaagtg ttggccgaat cgaagacgtc gtagaaaaag cgaaaacact aggctactag
    12961 aaaggggtgc cccatggatc aatatttaac agtaaatgtg gtaactcctg ccggtttggt
    13021 ctatgatcac catgcagcta tcgtcgttgc acgtacgaca gctggtgagc ttgggatttt
    13081 gcctaaacat gcaccaatca tcgttccatt gacgattgat gaagttcgtg taaaacgaac
    13141 agattcagat acccacgtcg attggatcgc tgttaatggc ggaatcatgg aagttcgtga
    13201 taatgttgtt tcaatcgttg ctgatagtgc ggaacgtgaa cgtgatatcg atgtatctcg
    13261 tgcggaacgt gcaaaacaac gcgcagaacg ccaaatcgaa gaagcaaaag caaaacaaga
    13321 tacgaacgaa ttgaaacggg caactgttgc gttgcaccga gcaatcaatc gtatcaaagt
    13381 atctaagcac tcataaaatg agatgcggat gtttatccgt gtttaagaac agtaaaaaga
    13441 ggttatgaca gaagtggtca gcttcaagac ataagaagga atttacgaaa attgcttctc
    13501 aaatttttgt gaaatctcag cttatttttc gaagaagcta cttctggaac accgtatatc
    13561 ggaggttgtg aaatcagcgt tttgtcctga gtattagaga aacaaatgga aaatagttcc
    13621 tcatattttg ccgttttttg agctaatacc gagggtcaga tgattgaaca ccgtttattt
    13681 ggaataaggg actg
//
LOCUS       DAIGQM010000071        13399 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.074, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000071 DAIGQM010000000
VERSION     DAIGQM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.074"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(59..601)
                     /locus_tag="NOA48_002260"
     CDS             complement(59..601)
                     /locus_tag="NOA48_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCI0790496.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            736..1125
                     /locus_tag="NOA48_002261"
     CDS             736..1125
                     /locus_tag="NOA48_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790497.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1129..1893
                     /locus_tag="NOA48_002262"
     CDS             1129..1893
                     /locus_tag="NOA48_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0790498.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2022..2969
                     /locus_tag="NOA48_002263"
     CDS             2022..2969
                     /locus_tag="NOA48_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790499.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3099..3839
                     /locus_tag="NOA48_002264"
     CDS             3099..3839
                     /locus_tag="NOA48_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790500.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4130..4798)
                     /locus_tag="NOA48_002265"
     CDS             complement(4130..4798)
                     /locus_tag="NOA48_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0790501.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4932..5219
                     /locus_tag="NOA48_002266"
     CDS             4932..5219
                     /locus_tag="NOA48_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790502.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5635..7173
                     /locus_tag="NOA48_002267"
     CDS             5635..7173
                     /locus_tag="NOA48_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCI0790503.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7170..8135
                     /locus_tag="NOA48_002268"
     CDS             7170..8135
                     /locus_tag="NOA48_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790504.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8122..9444
                     /locus_tag="NOA48_002269"
     CDS             8122..9444
                     /locus_tag="NOA48_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0790505.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9507..9611
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9685..10428
                     /locus_tag="NOA48_002270"
     CDS             9685..10428
                     /locus_tag="NOA48_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790506.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10443..11435
                     /locus_tag="NOA48_002271"
     CDS             10443..11435
                     /locus_tag="NOA48_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0790507.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11447..12184
                     /locus_tag="NOA48_002272"
     CDS             11447..12184
                     /locus_tag="NOA48_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790508.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12174..12896
                     /locus_tag="NOA48_002273"
     CDS             12174..12896
                     /locus_tag="NOA48_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0790509.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(12980..>13399)
                     /locus_tag="NOA48_002274"
     CDS             complement(12980..>13399)
                     /locus_tag="NOA48_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0790510.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4411 a         2295 c         2787 g         3906 t
ORIGIN      
        1 aaaactgtct aacatttaaa atttaattta gatattagac agtttttaag tttgtgagtt
       61 attttccttg tcgttttctc acttttttag tccagaaacc acctgaaata tattttggct
      121 cataagaaat gataaaagca cgctcttcga tttctttgat caggcgatac agttcacgtt
      181 cgctttttct aggagaaagt atttcgagaa ctagccgctc accttccagc cccattgcag
      241 aagtctgtgt cacaccataa ccgtgttctc tcagtatacc cggcaaactt ttatcttctg
      301 cgctatttgc tggcaaaatc gttgtgacca tgatgtatcc taatgccaat ttgtcttcaa
      361 tcaaaattcc gacactgata cctactgcgt aacctaacgc atagacaaat aaattcagtg
      421 gattatctaa acgatctaaa acaagggata agccgacgat ataaatcgtg atctcgacca
      481 tactgacaag tggagcaatc agtcgatagc ctttcattgt caacatgaaa cgtaacgtgt
      541 tcagagtgat ataagcaaaa ttaatgagga agatcatccc caacattttt ggatcaatca
      601 tttgtaaaac tcctttcatt tatataacaa caatatcaaa aaaaatcgta agtgaagaaa
      661 aattgaaact ttatacatac aaaaaaatga taaaatgatt ataatagaat tataaagata
      721 ggttaggtga ttaaaatgaa aacggtcaat cgtgtgtttt gtgccagcca cgtgctaagt
      781 ctccttctca gtatatactt aggtgtctat tcgattcaac agccaattga ggtagagaac
      841 attgtttttc agatgtcgct gacagatggt ttaattttaa gcgttttttt ctttttgata
      901 ctgtttattg gtaatatttt cggtagcgtt gccagttttt tgaatttttc tatttatcca
      961 ctcctttcgc tagcattagg agtggtggga ctttgttctc tgtgcttatt tcccgagcca
     1021 ttcagtcctg catttatatt atttggtaca ctgaacctgt tccagacaac tgttggagca
     1081 tggttgctat ggcgatcagg aaatttaatg aaaataggtg agtaacaatt gaatccaatt
     1141 atattgaaac gttctgtcca tcatattcca gtgttagaag ttgttctgaa agaattaaga
     1201 gaggaacgta ttcccgttgt catctattat cacggatggc agacaagtaa ggagttagtt
     1261 ttgacgcaag gaagaaaaat tgcgcagcag ggcattcgtg tgatcctgcc agatgcgatg
     1321 aatcatgggg agcgcaaaca gccggtttct tctattccat cctatacatt ttgggatagt
     1381 atctacggaa atctgtttga atttgacaca cttatcaagc atttagaaaa aagaggtctt
     1441 ctacatgatc agcttgcagt tggcggggtt tcgatggggg gaatgacaac atgcgccttg
     1501 ttggctaaac atcctcatat agtagcgggc gtgtgtttga tgggttcccc tgcacctttg
     1561 gaatatggaa aagaaatcgt aaggcgcgca tcggaatata attatgtcgt accaaaagac
     1621 tattttgatt tgatttcatg ggttaagagc tatgatttgt cattgcagcc ggaaaagtta
     1681 gctggacgtc ctctgttctt ttggcatgga caagctgacg aaaaaatccc ttatatacaa
     1741 acggaacgat ttgtagaaaa aaatcggcat aagtcttacg gaaaagaaat tgtttttcgt
     1801 tcctcaaaaa cacagcgaca tatggtacaa ataccactaa tggaagaagc ttccactttt
     1861 ttagcaaaaa atttgataaa aaagtataaa taattgaaac ggaaaatcac tcatgacgat
     1921 agaggatttt ccgtttttta ttttgggcta taataaactc tgttaggaaa atttggtata
     1981 attgatagta agaatgacaa catgttagaa aggaagagag catgcccact ttagcagatg
     2041 ttgcaaaacg tgccaatgtt tcaaaaatga cggtctctcg agtcatcaat catccggaac
     2101 aggtgactga cgaattgaaa gagttagttt tctcagcaat ggctgaactg gattaccgtc
     2161 caaatattgc tgcaaaagca cttgtcacga atcggtcgca gatcatcaaa ttatttatac
     2221 tggaagaaat cgacacaact gagccctatt acatgaattt gctgatggga atcgctaaac
     2281 ggatcggtaa agcgcattat tctctccaat tagttacaaa tgatgccttc gacgtcggtt
     2341 cttgtgatgg atacatcatc acaggtgtca gaaaaaaaga cttcgattgg atcgaccgtt
     2401 tggaaaaacc agttgtcttg tttggggaaa attctgaagg atatgattat gtagacagcg
     2461 ataatgaata tggtacagca aaagcaacgc aatatgcctt agaaagagat tatcaaacga
     2521 ttatttatat cggtatcgaa gtggacgagc cttttgaaat ttcaagggaa actggttatt
     2581 tatctgtgat gaaggaagtt gatcttccta gtaaaatctt gcggtttcca aatcattcga
     2641 cagaagtaga aagatatatg acagaaaact gggcagattt tacagataaa acttgttttg
     2701 tatgtagttc agatcggcta gcactaggag cagtaagagg gattataaat gctggaggac
     2761 acttgcccga agaatttggt gtgattggat ttgatggggt atttttagac caaatcagtt
     2821 cacctaaatt gacaacgatc aagcaagata ttatacgtat gggtgaagta tgtggagaaa
     2881 tgttgttaaa aaaaatagaa gaaaaagggg cgagtcaagg ttatcgtcgt ttttttcctg
     2941 aactagttat cagagagaca acgaattaag tcttattact atatatatat ttatgaaatt
     3001 catcgctatt ttcttaaaat aatcagcgca ttgctactga aaacaatgaa tctgtgctat
     3061 tattgagaaa agttccattt ttgagaagga tggtttgaat gaaagaaatc agacgaaaac
     3121 atttccgttt tcctgcgtac gatgatgagt taggcgtaaa attaaccaac gacaagaagc
     3181 gagtattatt tgacggacaa gaagatcttt tgactgaaca gaatcagtcc ccgtttgaac
     3241 agatgaaaga atttcatttc acgaacacga acaccgagaa aatccgtcgc aagcgtcgtg
     3301 caacaaatgg attgaagtca gctccgcgta aggaaaattt ggaaaagcat aaaggaaaat
     3361 taccggatta taccggccat taccaatcag aaatcacatc gacaggacga aaaaaacttt
     3421 ttggtgattc ctctcgttct gtcagacaaa gtgaaacaag gacagagtcc aagcatacta
     3481 cacgaaacgc atctgttgac acgaaggtgc gggagcgttc ttattttgtt cctaaatatg
     3541 tacccgcatc gattatccca gaccctagag aaagcaaaat ttctgaggat catttaatcg
     3601 aatcgatgaa aaaaacggat gactcttatc tgttgttcga tacagaaccg acgccgtatc
     3661 aagaaaaaag aaatggtgag ccgtctgtac gaacattcaa tcgaacaaaa acgttagagg
     3721 aaacaaagca gtcagaagaa aaaaaatcga aaaaaagcca tggtatctta gaacgctcat
     3781 tacaaggatt gatcgatgat caaggaaact ctttgggaga aaatagctat tttaaataag
     3841 tgatatacaa atttatattc ggctacagtt ggaaaggaaa cgctgcggcg tttccttatt
     3901 ttatactcta tccgaaagtt tatatcgtat cctcaaattt ttttgagttt aagcgaattt
     3961 tttctcccaa taagtaagaa aataatggca aaataaaaaa acaaactatt ttcgcagatc
     4021 gtttgcaaaa atagtttatt tttttataaa gaagatttta ctgaataata tcattttagt
     4081 ttacataatg atatttctgt aaattaaata aagtagtgaa aaataagaat cagtgctcta
     4141 actgttcaag aggatcaagt ggttcaaatg tttctgtagt ctgttttgct tccaattggg
     4201 gcaaaacaga tccaatttcc agatacttca ctttattcaa tgtataagat agaatagaac
     4261 agctaagtaa tgtatacaga aaatgtgtga gatccaaata aagcaaggag acaactaaaa
     4321 taccaaaagt aatcaagaaa agacttttgc caatcttaat atgaaaatat ttttcaatgg
     4381 cttgataaat gatatctgtt ccgcctgtgc ttccgccgaa tcgaaagacg agaccgcaac
     4441 caatgccaga aagaatacct gtcatcaaac tattgatcag tagactatct acagcaaaat
     4501 gtatatgaag gctctcccat aaatgtaaaa agaaaactag cgcaaatgtt ccgacgatcg
     4561 tccggagaaa agcgtgtttt ccaaaaagaa acaatgagat aagcaataaa ggtaaattaa
     4621 aaagcagtga agtgacagaa ggagcgaatc caaaaagatt atgcaaaagc aaagcaatac
     4681 cagtaacccc accatctgcc agcttagatg gaatattgat tcctgtcaca gctaatccgt
     4741 agattcctgc gcctaaaatg attccgcaca attctgtaaa taaatttaat tttttcattt
     4801 ctagcctctt ttcttttgaa aattttcagc aacttcttta ttatactgac ttatactctt
     4861 acttcaagag gaaaatgaaa aaaaattatt tttggctgtt tctttttatt tatcaaataa
     4921 ggagtggaaa aatgcgagca gcagacttat tgacaattct tacaaaatca cccaaaaaaa
     4981 cagagtatca aggagttttt ttggctcaag aacaaaaact ggtgcctgtg acaatggtcc
     5041 agataaataa agcaaatcaa tttatctttt tatttgaaca cggcaaagca ccacttgcta
     5101 tgaaagacat ctttcttttt ttgatgaaga accgtgagaa agctgtttat tatcagtcaa
     5161 aagaagaact cattcctctt tatggagtga aagagataga aaataaagtg gtgatataag
     5221 taaaaataag aaaacaagac gtttatgatg tcaaaacaac cattttttac atttttggca
     5281 aaaaagtgtc atgatacagt ataatattcg ttgaacaggc caataaaggt gttctccccc
     5341 acgagatttc tactttattg gctgtttctt tttattaaaa taaaagttgt gtgtgtaaaa
     5401 aagatatagc tgattccaag tgacaatttc gtatagattt ttatggtatt cgtagtgaaa
     5461 aaacgagaac caaaaagttg atccgacttt gttgcttgga ttcttttttt gtcagcatat
     5521 ttagaggtat ttttttcttt tttttgttcg tgctgtaagg ttaaggcaag acaagttagt
     5581 tgggaaaaag gaaagaaatg tttatactta aagaataaca gaaaggaagg tcgcatgaat
     5641 aattttatac aaacattaag tgaaagaaaa ggcgagttgc tggaagctgc atttcaacat
     5701 ctgtccattt ctctcatttc tttgctgatt gcagcactga ttgctattcc tttagcgatt
     5761 tgggcagcca atcataaaaa aatggcagaa gtcttattgc agatcacggg tgtgctccaa
     5821 acgattcctt cacttgcctt attaggttta cttatcccat ttgtagggat cggaactgtt
     5881 ccagcattga ttgcacttgt tatttacgct ttgcttccga ttttccaaaa cacgtatatt
     5941 ggtctagctg aaattgaccc gtctattgaa gaagcagcgg tagcatttgg tatgtccaga
     6001 atgagacgct tgctgaaagt agagcttccc atcgcattac ctgtcattat ctcaggtatc
     6061 cgaactgcct tagttttaat catcggtacg gctactttgg cagcattgat cggagcaggt
     6121 ggattaggga catttatttt gttaggtatt gaccgaaata cacctgtttt gacattgatt
     6181 ggtgcgatca gttctgcctt gcttgcaatt atattcagcg gactgattcg ctggttgcag
     6241 cataagaaac ctcgatattc catcattact ttagcagcag tggtgtgttt atttggcggc
     6301 gtttctttat atcagtctgc cttgtttaaa aatgaaacca tcacgattgc tggaaaatta
     6361 ggagcggaac ctgaaatcct gatccaaatg tataaagaat tgattgaaga caacacaaaa
     6421 acagaagttg aattaaaacc gaattttggc aagacgagtt ttttgttcaa tgcactggat
     6481 caaggtcaaa tcgatatcta tcctgagttc acaggtactg tcctagaaag cttggtgaag
     6541 gtacctgaag caatgaaaag tgctgatttg acaaaagaaa aaacatatga cgaagcagaa
     6601 gaattattga ataagcaatt cgatatgaca ttattaaaac caatggctta ccaaaatacg
     6661 tatgccttgg cagtcaagag atcttttgcg aacgaacatc aacttaaaaa gatttccgat
     6721 ttggcagcta tctctgatca gatcaaagcg ggattcacac tggaatttat tgatcgttca
     6781 gatggatata aaggaatcca agaagcatat ggcttgaatt tttcaagtgt acaaagcatg
     6841 gagccaagtt tgcgttacca agcaatcaat aatggagatg tcaatattgt ggatgcctat
     6901 tccacagata gccagctcaa ggagtacgat ctagtgactc tagaagatga tcgagggtta
     6961 ttcccagctt atcaaggcgc accgctgatg aaaaaagatt ttgctaaaga acatcctgaa
     7021 atcgttaaag cactgaataa attaagcgga aaaataacag aggatcaaat gattgatatg
     7081 aattaccaag tcaatgtcga aaagaaaaag ccgacagaag tagcacgaat cttcctgaaa
     7141 aatgaaggat tagtaaagga ggaagatcag tgactaaatt aatcgagttc aaacatgtgc
     7201 aaaaaaagta tgatggaaag tatgtcatcg atgacctaaa tctggcaatc aaaaaaggag
     7261 aaatctttgt tttggttggt ccttccggta gtggaaaaac aactactttg aaaatgatca
     7321 atggattatc taaaccatca gcaggagaca tctacttcaa aggaaaatcg ttaaatgaat
     7381 ataatctgca gaaaatgcgg tggaatatgg gatatgtgct gcagcaaatc gctttgttcc
     7441 cgaccatgac agtcaagcaa aatattgaag tcatccctga aatgttaggt tgggaaaagc
     7501 agaaaagagc agaccgtgta gatgaacttc ttcaaaaagt tggcttatct cctgatattt
     7561 atcgagatcg tatgcctaga gagttgtctg gaggagaaca gcaacggatc gggatcatcc
     7621 gagctattgc tgcaagccca gatgtgattt tgatggacga gccatttagc gcattagatc
     7681 cgatttcaag aaactcatta caagaattgg ttttgtcctt acacgaagaa ttgggcacga
     7741 ccatcgtttt cgttacgcac aatatggaag aagcaatcaa gctaggtgat cgtattgcat
     7801 ttatgaagga tggagaaatt atccaatgtg acacaccaga gcagttattg atgaatccta
     7861 aaaacgacta cgttcggcat ttctttgatg aaccgaaaca gacgaaagag tggcgagtag
     7921 aagatttagt cgtcaatgga tatttcttaa atgaaatacc agaaaatgct cgtcaacaag
     7981 tttgctttga tacgcctatg aaagaagtat attcgcttct ttcggtgtat ccaagcattg
     8041 tgatagtaga aaagcaaaga agtattgggt cgctgacaag taaagaaatc tttgcttttt
     8101 taagtcgaga ggaggaagga aatgaaaaca tatgatgcaa tcatcatcgg ttcaggtgtg
     8161 agcggcttaa gtgctgctta tggattgaaa gaagcaggta aaacagtact agtggtcgaa
     8221 gaagatctat ggggcgggac ttgtcctaac cgtggatgtg atcctaaaaa agtcttgtta
     8281 agtgcagtag aggcacgtaa tcgggtaaaa caattgagtg gaaaaggttt taacgagatc
     8341 ccaactgcca actgggaaga acttcaaaaa ttcaaacgaa catttacgga tccagtccca
     8401 gaaagccgaa aaaaacaatt agcagaagct gaaatcgatc atctttcagg aaccgctcgt
     8461 tttttggatg attcatctat tgaagtcaac gaagaagtct tccatgcgga ttacttagtt
     8521 ttggcaaccg ggcaaagacc tacgatctta ccagtggagg gaaaggaata cttgaaaact
     8581 agtgcagact ttttatcatt gcctgtactg cctaaagaaa tcatttttat cggtggtggt
     8641 tatattgctt ttgagctagc tacgattgcc aatgctgcag ggagcaaagt aaccattgtc
     8701 catcataatc aacggccatt aaaagaattt gaggcgtctt tggtagagga agccgtccat
     8761 caaatggaag catctggcat tcagtttgct tttggtgttg aaacccaaaa gatcatttca
     8821 gaaggtactc gctatcgttt agtcggaaaa gagacggaat tagtagcaga tatgattttt
     8881 tgtgcgactg ggagacagcc gaatacagaa tctttagcac ttgagcaagc gaatatcgtc
     8941 tttgataaac acggaattgc agtcaatgat tatctgcaaa cgagcaatcc aaaaattttt
     9001 gcgtgtggag atattgtttc aaggaaaacc ccaaaattga caccagtcgc cacttttgaa
     9061 ggaaattatg tagctaagcg gataacggat gcaacaagcg aacctatcaa atatccgatt
     9121 atacctacga tcgtctacgc cagtcctaaa cttgctgaag taggagttac aaaaagtcac
     9181 gcctcttcgt cagatcaagt ggtagagatg gatcttacca gttggttcac ctatcatcgt
     9241 gtcaatgaac cagttgctaa ggctgaattg acctttgacc agcaaaatta tttgattggt
     9301 gctgcagtga ttagcgagca agcagacgaa ttgatcgatg atttgacact cgtcatcaat
     9361 caaaaattga ctaaaaaaga gttggatagc tatatcatgg ggtatccgac attggcaagt
     9421 gatctctcct atttattgaa ataatcagca tgataactaa agcgcttgtt gctttttcct
     9481 tcttgtgcta cactttaaaa aatgaatacc tgtttctggg gatgtcgtag acgacatgag
     9541 agtaagttgt gaacttagac ccattgaacc tgtcagttaa tactggtgaa gggagaaaca
     9601 tagcagacgc ttgaagcggg ttactatgtc gtgcccattt caagcgtttt ttgttattca
     9661 tattagaaga aaggaggtaa caaaatgaag aaaaatcttt atccagcagt cagtatggca
     9721 ttcattttaa ttatttggca gattgttgtc atagtttgga aaatacctgc ctttatttta
     9781 cccggacctg ctgctgtatt ttctgcatta gcggcagatg cacaagtatt actttcccat
     9841 tctgtcacga cattaaatga agcagtgctt ggtttggtaa tagctagcgt tctttctttt
     9901 attactgcct tggcaatgga ttattggaag tttttagaaa tgtcttttta tccgttacta
     9961 gtgatttcac aaatgttgcc aatcatggtg ttagggccat tacttaccct atggtttggt
    10021 ttcggtatgc ttccaaaagt gatccttgtt gtcttgataa gctattttcc gatcgtagtt
    10081 tctttttcgg atacattgag gaaagtatca aaagagcaaa tcatcttttt gaaaacgatg
    10141 ggggcagata cagggaagat ttatcgaata tataaaatac cagcgggttt atccggcttc
    10201 ttttccggtt taaaagtggc tgctacttat tgtgtcagcg gagcagtcgt tggagaatgg
    10261 ctaagcgctc aagcaggctt agggtattac atgatacgcg taaaaaacag ctaccagatc
    10321 gataaagttt ttgctgcgat catttgtgtc attctattga gtttattgct gaatggcgct
    10381 tgttcattat tgaaaaaagg gtattatcgt atgctttata ttttttaaga gaaggggatc
    10441 aaatgaaaaa attatggctt ttattaccgc tactgttgct tttatccgct tgtggcactg
    10501 caaaagaaac aagtagcaaa caagaaataa aggatttgaa aaaagtgaca cttgttttgg
    10561 attatgtacc gaatactaat catactggca tctacctagc aaaagaaaaa ggctattata
    10621 aagaggctgg tttaaatgtc caaatcatcg aaccaggaga taattcgaca agtattggtc
    10681 tagtaggtgc ggacaaagca caatttggtg taagttatca agaagatgtc acttatgctc
    10741 acgcagatgg acagaatata ccagtcaaag caattgctac agtgatcaaa cataatactt
    10801 ctggattcgc caccctatca gacagtaaca tccattcacc aaaagatttt gaaggaaaaa
    10861 catatgcagg ttggcaaagt ccaagtgaag aagctgtctt aaaagctgtg atggaaaaag
    10921 acggcgggga cttttcaaaa ctgacaatgg taggaagcaa tggagaaggg ccagaaagct
    10981 taggaaaatc ctcagatatc caatggtact ttgaaggttg ggatatgatc aaagcaaaag
    11041 aagcgggtat tgaactaaac tatatcccat tgaaagaatt agatgaacgg ttagattact
    11101 atactccggt aattattacg aatgatcaac tgatcaaaag tgatccagaa ttggtacagt
    11161 cttttatgga tgccacgaaa aaaggctatc aggaagctat taaggatcca aatgacagtg
    11221 ctaaactgtt gcaaaaatat gcaaaagaaa atgatcggac gtttttagaa gaatcacaag
    11281 cattcttgtc aaaaaattat acggatgatc ctgagaattg gggattgatg gaagaaaaag
    11341 tttggcgcaa ttatacagct tttatgcagg aaaacggatt gatcaagcaa gatgtacctt
    11401 cgcaagaact attcactaat cagtttataa aataggagtg atagatatgt caatccaaat
    11461 cagccacttg aatgtagtca ttgaaaacct gaaaatatta gaagacatcc atttcactat
    11521 ccctaaagat acctttacat cgattgtcgc gccaagcgga gccggtaagt caacattgct
    11581 gaaaacttta acaggagtcc agcctatgac ttctggaacg atcaaagtag acgatcaaaa
    11641 agtaactggt ctccatacag catttagtta tatgccgcaa gaagatatgt tacttccttg
    11701 gctgagcgtc tatcaaaacg ttacgttata tcaaaaaatc aatcatctaa caatcaatga
    11761 ggaacaagta agggattatc tggatatctt tgggttaaac ggctacgaac attttttgcc
    11821 ggaacaatta tctggcggga tgaagcagcg aacggccttg ttacgaacaa tcatgaatcc
    11881 ttcttcttac ttgcttcttg atgaaccatt tggagcgtta gatgctatga ccagagggca
    11941 gatgcaagac tggatgttga agctgcctaa aaaagcaaag cggactactt tacttgtgac
    12001 gcatgatatc gaagaagcaa tttatttatc agacaggatt cttgtgcttt ccgcccgtcc
    12061 ggcacatgtg attgctgaga ttcaagtgcc tgaaaaacga cggtcacgtg aatggctact
    12121 gcagcaatca gagttgaagc aaacgattta tcagttattg gcaggtgaat tagatgttaa
    12181 gtgatgctca ttgtcattta gatgggagtc agagtttagc actccttcag caggaacaca
    12241 cgattttgac gatcatcaat tgtgattcgc cagaagaatg gaaggaaaac agacagcttg
    12301 cagcaagtaa gactcaagcc ttaagttacg gtatccatcc ttggaaagca gatagctata
    12361 cgtttgaaca agttgagcct tttttgaaaa aagcaaggat catcggtgaa atagggttag
    12421 ataatatttg gacgaatgta ccgatgacta cacaaaaaaa agtatttgag cgacagcttg
    12481 cttttgcagc cataaatgag aaacctgttg tactgcacac aaaaggatgc gaaaaagaga
    12541 tcttaaatta tatccaagct taccctaatc actatttgat ccattggtat tcttctttgg
    12601 actatcaaca agactatatt gatttaggct gttatttcag cattggtctt gatttgaaaa
    12661 agaatccagc agtctggcaa ctagctaaag cagtcccaat cgaccactta cttattgaaa
    12721 cggatggact acatgcagca gagtgggctt taggggggat tttttcagaa aaagattatg
    12781 tctcactgct tgaagaacag ttaaagacaa tcgctgagat caaagagcta tcagttgaag
    12841 aagttaaaaa aaatacttat caaaacttgg aacgtttcat tagattaggt aaataaaaaa
    12901 gagatgtgac acaactagtg tcgcacctct ttttggcttt ctttgtataa aagtaaactg
    12961 tttgattaat aaatgaatct tagtaccaac cgtttgcttc ccagaatgct ttcgccgctt
    13021 cccaagaacc ataacgtgaa gtaacatatt gttctgctac tctttcttgg tttgcagcag
    13081 agtagtcacc atttaagtaa gaagaatcta attggtaacg tccgatgtaa cgtccgttcg
    13141 ttgctgtgta agaaccgctt gattcttttt gtgcgatcca ttcttttgca gagcttgtgc
    13201 ttgctggagt agcagcagtt tctgttacag caggagcagg ttgtgtttca gcaacaggcg
    13261 ctgcttgttt ttccgtttga accgtttctt gtacaacagg ttgttcagct tggactggtg
    13321 cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc agagccttct gttgggattg
    13381 ttaattgttg tcctgagta
//
LOCUS       DAIGQM010000072        13351 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.075, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000072 DAIGQM010000000
VERSION     DAIGQM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.075"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(45..1364)
                     /locus_tag="NOA48_002275"
     CDS             complement(45..1364)
                     /locus_tag="NOA48_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0790511.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="NOA48_002276"
     CDS             complement(1361..2014)
                     /locus_tag="NOA48_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790512.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="NOA48_002277"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="NOA48_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="NOA48_002278"
     CDS             complement(2724..3440)
                     /locus_tag="NOA48_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCI0790513.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="NOA48_002279"
     CDS             complement(3490..3699)
                     /locus_tag="NOA48_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790514.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            3976..5249
                     /locus_tag="NOA48_002280"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="NOA48_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="NOA48_002281"
     CDS             complement(5356..6387)
                     /locus_tag="NOA48_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790515.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="NOA48_002282"
     CDS             complement(6394..7224)
                     /locus_tag="NOA48_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790516.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="NOA48_002283"
     CDS             complement(7221..8036)
                     /locus_tag="NOA48_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0790517.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="NOA48_002284"
     CDS             complement(8033..8857)
                     /locus_tag="NOA48_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCI0790518.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="NOA48_002285"
     CDS             complement(8847..9947)
                     /locus_tag="NOA48_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0790519.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="NOA48_002286"
     CDS             10125..10910
                     /locus_tag="NOA48_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HCI0790520.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="NOA48_002287"
     CDS             10943..11326
                     /locus_tag="NOA48_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI0790521.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="NOA48_002288"
     CDS             11402..11533
                     /locus_tag="NOA48_002288"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0790522.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="NOA48_002289"
     CDS             11502..11738
                     /locus_tag="NOA48_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0790523.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="NOA48_002290"
     CDS             complement(11816..12787)
                     /locus_tag="NOA48_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCI0790524.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4057 a         2914 c         2307 g         4073 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttatccag a
//
LOCUS       DAIGQM010000073        12772 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.076, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000073 DAIGQM010000000
VERSION     DAIGQM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.076"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(56..235)
                     /gene="rpmF"
                     /locus_tag="NOA48_002291"
     CDS             complement(56..235)
                     /gene="rpmF"
                     /locus_tag="NOA48_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0790525.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(293..862)
                     /locus_tag="NOA48_002292"
     CDS             complement(293..862)
                     /locus_tag="NOA48_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCI0790526.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1048..1950
                     /locus_tag="NOA48_002293"
     CDS             1048..1950
                     /locus_tag="NOA48_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0790527.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(1985..3769)
                     /gene="pyk"
                     /locus_tag="NOA48_002294"
     CDS             complement(1985..3769)
                     /gene="pyk"
                     /locus_tag="NOA48_002294"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCI0790528.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3843..4805)
                     /gene="pfkA"
                     /locus_tag="NOA48_002295"
     CDS             complement(3843..4805)
                     /gene="pfkA"
                     /locus_tag="NOA48_002295"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCI0790529.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(4973..8287)
                     /gene="dnaE"
                     /locus_tag="NOA48_002296"
     CDS             complement(4973..8287)
                     /gene="dnaE"
                     /locus_tag="NOA48_002296"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCI0790530.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8518..8703
                     /locus_tag="NOA48_002297"
     CDS             8518..8703
                     /locus_tag="NOA48_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCI0790531.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8765..9961)
                     /locus_tag="NOA48_002298"
     CDS             complement(8765..9961)
                     /locus_tag="NOA48_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0790532.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10131..11567)
                     /locus_tag="NOA48_002299"
     CDS             complement(10131..11567)
                     /locus_tag="NOA48_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0790533.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11860..12669
                     /locus_tag="NOA48_002300"
     CDS             11860..12669
                     /locus_tag="NOA48_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0790534.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3806 a         2682 c         2263 g         4021 t
ORIGIN      
        1 aacctcaagg ctccatggtt agccttgagg ttttacattt tctaattaaa atgtattaag
       61 cttcttttga cattacgtcc ttaccatcat agtaaccaca atttgcacat acgtgatggc
      121 tttttttcat ttcaccacag tttggacatt cgtttaaccc tttgattgtc aatttgtagt
      181 gtgtacgacg ttttgctttt ttagcttttg atgttcttct agctggtact gccattttgc
      241 tacacctcct tgtaaagtct tgtatctaaa ttagacacaa tatattccaa tcttacttgt
      301 tatcgtcgtc ttttgattta gaatcaaaaa gttcagatag ttttgcaaga cgaggatcaa
      361 ttttattctc ggcttcttcc atttttctgc gctggtattc ttcttcggaa acaacttccc
      421 aatcattgcc ttttggaagt tctgttgctg cttcctcttc ttttgtcaat acccgcattg
      481 gaatcgccaa taagatgttg tcttcaatcg actctgctaa attcaataat ggaccttcaa
      541 ttagcaaaat ctcatctgca gacatttgtt catctctact ttggaattgt tcttctgtca
      601 tgaatacttc gtctacagaa aaatccatgg gcagttcaac aggttctagt gaacgtgttg
      661 aaggaactgt caaagtcgtc tgcacagtgt aatgaacgat atagcctttc ttatcaactg
      721 agaccaaacc ttcgacttcc actggcgcaa catcaagtat taaattgtct cgcttcatga
      781 gagcggcttt caagtcgagc gtctcatgaa aagttaacgg tgtctcctgg tattttctca
      841 attccaataa agaccatttc atttttcatc actcctaagc aacaaaagca attatacagg
      901 gcaaaaagca tgttgtcaat gaaattttct tgacaccttg cagttcataa aaaaacagaa
      961 aaatctttat tagaaagcct ctgtttgcta tcatcctcag aatcatttac aataatcatt
     1021 attccattaa aggagcggat gatcttcatg aacacgaaag atatcgaata ctatgtccaa
     1081 atcgtcaaac aaaaaaattt tacgaaagtg gctaattatt tccgtgtgag ccaacctact
     1141 attacatatg cattacaacg tcttgaaaaa gagtttgaca ccgtacttat tacaagagat
     1201 cgatcgcatc acgaattaat cgtcacgcct tctggaaagc agctgtttct ccatgcacaa
     1261 accattctcc aagagatttc tactgcaaga gctgaaatca ctcagttgca aaagaaaaag
     1321 cttcgttttg gcatgcctcc tattatcggc aatgaatact ttcctaaact gtcaagttac
     1381 tttatcaagc atgaattgat gaatcaaatt gagattaccg atggaggctc tcgggactta
     1441 tacgggatga tccgacaagg gaggatcgat ttagctgtat taggctcaac acagccaatc
     1501 gtggatcaat atttagaaac agagttactt ttggacaaac gtttcatgat cgtcgtgcca
     1561 cctacacatc ctctttccaa gcaggatact gtctctttca aagatatagc agatgaacag
     1621 tttgtactat tgaacgaaca ttatgtccac cccgcagcat tcactaagct ttctaaacaa
     1681 acacatactc atccaaaagt tgtttatcaa agcaatgact tgacgatttt aaagagtatg
     1741 gtccgagaaa atgtgggtat cggttttttg gcagagattg ctgtccatcc tgaagatcat
     1801 ttagtttgcc tccctctttc agatgaagtt cagcctcgct tcttgatttc attggcaaaa
     1861 cgaacacagc agatcgtcac gcctcttcaa gaacaagtag tccaagttat ccatgaattc
     1921 gttacagcac aaaaaaacag ctcttcgtaa aagaagagct gtttttattt tttattaagc
     1981 taaattagat agctgttgtt tcgccacggt aaacgatgcc gcgacgtgaa tcaacggtaa
     2041 tcaattcacc ttctgtaatt gttgttgttg cgcctttagc accaacgatt acaggaatat
     2101 cttgtgcaat tcctacaact gcagcgtgag aagtcaatcc gccttcttca acgataacag
     2161 cagctgcttt ttcgattgca ggcatatatt ctttgtcagt tgatggtaca actagaacca
     2221 ttccgtcttt tgcttttttt acagcttctt cagcagatga agcaataact gcatttgcaa
     2281 cgacagattt ttgtccaacg ccttgagctt ctaataattt agaaccaatc atttgaattt
     2341 tcatcacgtt agttgttccg cgttcaccaa ctggtacacc agcagtgatc aagattaaat
     2401 cgccttctga tgcgaaacct aattcaacag cttttttagc tgctagttca aacatttcat
     2461 cagttgttga tggtttttca gcaactgttg ggtaaacgcc ccagtttaac atcaaaccac
     2521 gttttgtgcg ttcgtcaaaa gtaacagcca agatatctgc atctggacga tattttgaaa
     2581 tcatttttgc agtgtatcct gattcagttg cagcaacgat tgttttcacg cctagatttt
     2641 ttgcagcacg agctacagat aaaccgattg tttcagttac atctgtttta tcgaattcgt
     2701 tcaattggaa tgtacctaat tctgataatg cattttcagc ttcttggtcg atacgtgcca
     2761 ttgttgaaac agcttcaact gggtagtccc cgtttgcaga ttcaccagat agcattgttg
     2821 catctgtgcc atcaaataca gcgttagcaa cgtcagaagc ttccgcacgt gttggacgtg
     2881 ggttttcttg cattgattct aacatttgtg tagcagtgat aactgggata ccagcagcat
     2941 tacatttttt gataatgcgt ttttgaacca ttggtactag ttcagctggg atttcaacac
     3001 ccatatctcc gcgggcaatc ataacaccgt cagaaacttt gatgatttcg tcaatgttgt
     3061 cgataccttc ttgagattcg attttaggga agatttgaac atgagtcatg tctttttctt
     3121 ctaagatttc gcggatatct agaacgtctt gtgctttacg tacaaaactt gcagcgataa
     3181 agtcgatatc gttgtctaaa ccaaaacgaa tatcgtcagc atcttttgga gtaatacctg
     3241 gcaaactaat agaaacgcct ggtgcattta cccctttacg tgatcctagc atacctgcat
     3301 ttttaacttc tacgactaat tcacggtttg cttcgtcttt ttcaatgatt tgcatatcga
     3361 tcaaaccatc atcaaataaa atgtgtccgc caacgtgaac atcgtcaaat aatcctgggt
     3421 aagtaaccgc gattttttct tttgaaccta catgttcagg atccatagag atgcgtgttt
     3481 gatctcctac ttcaaatttg atgtatcctg cacgaccaaa atcagcttct gttgtgcctt
     3541 gaacagttgt acggatttca gctccttttg tatctaaaag aataccgaca tcttttcctg
     3601 tctttttaac tgcttcacgg accatagtca tacgtgataa ttgttcttca tggtcaccat
     3661 gagaaaaatt aaagcggaag acatttgccc cagattcaat caattgagaa ataatttcta
     3721 ctgagttact tgctggtcct aatgtactaa cgattttggt ttttttcatt taaaaaactc
     3781 tcccattcaa ttttgtttat ttaaagctgt acacagctta aatagcttgg tttctttcac
     3841 tcttaaaatg aaagtgaatt atttagatca tatagtgata agtctggttt atgtttgttg
     3901 ttttcaagtg tatcaatgat gtcagacgca acgatttcgt tgtcatggat accgacacat
     3961 aatccacctt ttccttcttg aagcaattcg acagcgtaag caccgaattt acttgccaac
     4021 acgcggtcgc gtgcgcttgg tgctccacca cggacaacgt gtcccaagat agatacacgt
     4081 gtatgatagt caccaaattc tgaaagtttc tcagcgaatt catttccgcc cattacacct
     4141 tcagccaaga tgatcaagca atgtttcttc ccgcgatcgc ggccttcttg gattttttta
     4201 gcaactgaag ccatatcaaa atcatgttct gggatgatga tttcatccgc tccgccagcc
     4261 acacctgacc ataaagcgat gtctcctgca ttgcgtccca ttacttcgat aacgaatgta
     4321 cgaacatgag aagtcgctgt gtcacgaata cggtcaattg attctagtac tgtattgatt
     4381 gctgtatcaa aaccgattgt gaaatcagtc ccaggaatat cattatcgat tgttccagga
     4441 atacctactg ctgggaaacc gcgttttgtc aaagccattg cgccatgata agagccgtct
     4501 cctccgataa ccactagacc ttcgattccg aattttttca attgttcgat tccttttaat
     4561 tgaccttctt cagttgcaaa ttctggataa cgtgcagaat acaagaatgt accaccacgt
     4621 tggatcttgt cacctacatc tgccacatca agacgacgaa tatctccagc aactaaaccg
     4681 gcaaaaccat aattgatccc gtatacttcc agtccttcgt aaataccttt acgaacaacg
     4741 gcacgaacag ctgcattcat tccaggtgcg tctccgccac tggtcaaaat tccgatgcgt
     4801 ttcataataa acattcacct cattaaaata ctttatccta agtatgactt aggtttacaa
     4861 ccatttttgc gttaaccacg actaacattc taacattatt tttctcactt gtcttgattt
     4921 acggataaaa aaatgaaaaa aaatgaaagc aagtagtatt ttttaccgta agttatttga
     4981 aaaccacatt atcttcgcca agcagataaa taagttgccc ctttatactc ttgctgtcat
     5041 ccacccaata agcatctgac agaactactt ttcgttgcgt tttttcgtga tacataacta
     5101 ctggtatata tcctgggtgt ttctgaaaaa tcacttgtaa ttgtttcatt atctcgggat
     5161 cttcccgttc ttctgtaata cgcaaatagc aagtttgtga aggatactgg gcttctaact
     5221 ggttaggatc agcaaagctt tctccaatta gttgcagttc ctgattatat ttgctgattt
     5281 cgctccgccc ttgaacaaag atcactcgat caacggcaaa caaattacga tatttacgat
     5341 aaagagttgg aaaaactgtg acagaaattt ctccactact gtcggttcct tcaacaaagg
     5401 ccatcagttc tccttttttt gtccgaattt ctctaacttc cttgatcatc actaataaat
     5461 tgactggttg attagggacg atatctgtaa tcagctgaac ttgtttagct aaacgaagac
     5521 gatcaaaccc ttctgcagga tgacctgaca aataaatacc taagtactcc tcttccagct
     5581 tcaagcgttc ttctagtgta tagtcagcga cttcttcttc ttttaatgcc atgattccca
     5641 gcaagtcaag acttccacca ctgtaaacga tattttggat ttttccttcg agatcaagca
     5701 tcaattgttt cctgttagga gataattcat caaaaactcc tactgctgtc agtgattgca
     5761 gtaactctaa tttcagccaa cgcttatcga tccgtatgag gaattgatcc actgactgga
     5821 acgggccatt ttgttttctt tcgtttaata tatcttctac aaaatcacgc cgaatacctt
     5881 ttatcgctgt cagtccgaat ctgatttctt ccttattgac caactcaaaa ctggaattac
     5941 tttgattaat ggacggcgag gaaagtttga gtttattttt acgtgcttct gcaatatatt
     6001 ctttcaattt tgatgtgtta tgccgaacag aattcatcag gctggtaaag aaagcacctg
     6061 gatgatgggc ttttagatac gccatttgga atcccacgaa tgaataagca aatgcatgtg
     6121 accgattgaa tccatagttt gcaaattttt cgatatattc atatacggtc gctgctgttt
     6181 tttccgaata tccctgttgt aatgctcctg atacaaaatg cgacttttct tcatctaata
     6241 cgtctttttt ctttttactc actgcccgtc gcagaatatc tgactgccct aatgtaaatc
     6301 cagccatagt cgaggcgatc tgcatgattt gttcctgata gacgatcact ccatatgtgt
     6361 ttttcaaaat cgggatcagt gaatcatctg ggtagcgaat ggcttctttt cctttcttcc
     6421 tggcaatgaa ggtatctata ttttgcatag ggcctggtcg atacaatgca ttgactgcgg
     6481 caatatcttc gatgttttct ggatctaatc ttcgtaaaac gttccggata ccagcagatt
     6541 caaattgaaa tactcctgag gtttcgcctc gttgaaacaa gagcagcgtt tttgcatcat
     6601 ttagcgggat ctcttttaat cggatctcat acccttctac tcgcttaaca gctttcaaag
     6661 taaaatcaat aatcgataag ttgcgtagtc ctaaaaagtc cattttcaaa agaccgattg
     6721 cttctacctc attcatcgta tactgggtca gaaaagcttc atcagaaccg cgttggagcg
     6781 gaactagttc aagtagattc ttatcgctga taactacacc tgctgcgtga gtcgaaacat
     6841 gtcttggcaa tccttctaaa atcactgcag ttttgaataa aagttggttt ttttcgcttg
     6901 cctgaactaa ttctactaat tgatgcgaag ttttataagc ttgggtcaat gtgattttca
     6961 attgattggg tattgctttt gaccagcggt ttgcttcact ttgcgataaa ccaaacactc
     7021 tagctgcatc tctaagaacc atttttgctg ccattgtgcc aaatgttgcg atttgtgcca
     7081 tatgatattg tccatacttt tctcgaacat aattcaatac ttcttcacgt cgattgtcag
     7141 gaatatccaa atcgatatct ggcatcgtaa agcgttcggg gtttaaaaag cgttcgaaca
     7201 gcaaatcata ttctaatgga tccacatctg tgatttctaa cacataggct actaatgaac
     7261 ccgcagcaga accacgacct gcaccggtaa cgattttgtt tctatgagca aaagccatta
     7321 catcccatac gatcaagaaa taatcatcga atcccatttg atggatgaca gataactcgt
     7381 agtccaaacg ttcttggtat tcctttgtat agtcagtgat tcggcgttcc acttgcgaat
     7441 agcataactc tcttaaatat tctccagctt gttttccatt aggaactgga taatgcggaa
     7501 gtaatttctg atggaactgg aattcaaatg aaatcgattc agctaaacgc tgggcgccta
     7561 ttacagcttg ggaaagaccc gctttttcga atcgtttgat catttcttgt tctgaaagaa
     7621 gatagacatt tgctgttagt ggtaaagatg cagataaatt ttctaaaggt atttggcttc
     7681 cctctttgat atgtttcatc acttcaagtg caaaaagttc ttcttgttgt aaactagcga
     7741 tgggatgtaa tgcacaaagc gaataatttt cttttatcac atactgatac cattcaggca
     7801 attgatcagg cgtgttttct gtcaagccga tataaaaatt tctagtaaaa acattttcaa
     7861 gtaaaaactg ccaatgaccg aaaaagttat cctctttatt gaaagcctca gaaacagaat
     7921 gatttgccgg aacaacaaac gctagatggt cggtttctgt catttctgca agttccaatt
     7981 tttcttggat catttttcgg ctggaaagtt tcatcagctg ctgataacct atttcatctt
     8041 ttgcgtacgc aagcaagcca taattttttt cttcataagt ataactaaga tgtaatccaa
     8101 tgattggctg tactccttct tctacacaaa tacgatagaa ttcaggtgca ccgtataaga
     8161 catctttatc cgttatggct aatgaagtgt agccttgttt ttttgcttct tgtacatatt
     8221 ctcgaatacg tatcgtactt tgtaaaagag aataagaagt aattgtataa agttgtggga
     8281 aaaacatctt gcattccgcc ttttttttcg ttaaaattca ctagcgttaa aaggtttgat
     8341 ccttttactt tcattaagat agcaggcgct gaagttgatt attccacttc atttgcttgc
     8401 ttgtaatctg taggaatgag ttctttcgca agaactcaaa ttttattgag atttggtctc
     8461 gtttctttac attcaaagaa aatctggtaa aattaagata gaaaagaggt gttctttatg
     8521 cgatatatcg ttacattatt ctgggctgtc gttctaggtc aagtagtcgg ttatattggt
     8581 gctgcattaa caagcggaac atatgatttt actttgacaa caatcatttc attcattgcg
     8641 ggtgtcatta tccttttgat tggtgcagtt gcgccaagaa aagaaacctc tgcccattcg
     8701 taaaaaaaca gccaagagct tgagatttct caagctcttt tttattttct actcctcacc
     8761 accattataa tctgctgcga agaactttac gaaagttgaa taaagaaaga agaatatttg
     8821 acagaacaaa caaacttgtc acaataaaaa cagcactgta attataagca tgcgcgactg
     8881 tcgatcctag catgggacct aaaacttgtc caaagttgct aaacatctga ttgtagctat
     8941 agattcggct gactccttct tgaggcgtaa tcttactgat cagtgtattg acagaaggca
     9001 tcaaagcgcc agttgaaaag cctaaaataa agcgaagtat acctaattgg agcggtgtag
     9061 tgacgaatgc cataggtaaa taacagcaaa atgataaaat gagtcctcca attagaactt
     9121 tttgattccc aatcttatcc cctagttttc ctagtttcgg tgaagaaaag acagcggaaa
     9181 caccagctat cgaaacaatc aagccgctga caaaaaggat attttctgta cttccgctca
     9241 attcacgaat atataaggtc aaaatagggc tgatcgtagt gattcctatc tgtaaaatca
     9301 aggtcgtaat gaagagaccg atcaaaatag agagatgatc catttttgaa aaaatttctt
     9361 tggtgcttat cagatctttt ttctcgattg gatggaagtc ttctttgact aagaaaatgg
     9421 tcaataccgt tgtgatcatc aacaaagccc ctgtgatcaa gaatacattt tccataccaa
     9481 accactgagc cagtgcaccg cccattgaag gtccgatcag atttccagca atcgctccgg
     9541 tagacaatgt tcctaacgcc catccgctct tttctctagg tgcctgtgaa gcaatcatcg
     9601 ctgtggcatt tggaatatat ccagacaaaa tcccattcca aaaccgcatg atcaaaagcc
     9661 aatacgcgtt tggtacaaaa gccaaagatc ccattgttaa tgtcatccct gctgctgcac
     9721 ggatcatcat gagttttcgg ccttttcgat cagctagatt tccccagatt ggtgcaacca
     9781 cggcagatgc aaaagcagtc acagagattg ctagtcccga aaacaattcg atttgatctt
     9841 ttggtgttcc tagttgctca acataaactg gtatgaatgg cataactaaa ctaatacttg
     9901 caccagtgaa aaaacagcca atccacgcaa tcactaaatt ttttctccaa ttaatctcca
     9961 tctatcatcc ctctttcgtc tcttttatca tacctatttt cgaataaaca agcaacgatc
    10021 tcgccagtaa aaagagaaaa atcccgcaaa ggtcatttta tatgtaacgt tctttttatg
    10081 taaaacaaaa agagatcaga acaaatactg ttccaatccc ttctctttag ttaaattgtt
    10141 gctagaatga tgaagttgat aatgaataaa atatcaacga tccacaaagc aacagaaact
    10201 tgattgtatt ttcctttgat tactttcaca attgtataga aaataaatcc tgctgcaatc
    10261 ccataggaaa tgctatagca caatcccata aagatcgatg caaagaaggc cggtaaagct
    10321 tcttccatat ctagccattt gatgtctgca aaagaagcca tcatcattac tccaactaaa
    10381 atcaatgctg gcgcagttgc ttgatttggt acaatggcga tcagtggaga gaataaacta
    10441 cttaatgcga atagcactgc cactactact gaagtcaaac cagtacgtcc accggccccg
    10501 atcccagctg cagattcgac ataagttgtt gtattcgatg taccaaagat agcccccaca
    10561 gaagtagcga tcgcatcggc aaatagtgct ttatccattt ttgttttgaa cccacgacca
    10621 tcttccaacg cgatctcgtc ttcttttgag aaaatacctg tgcggcgtcc tgtaccgata
    10681 aatgttccga tcgtatcgaa agtatcagat aaactgaatg cgatgatcgt catcaatact
    10741 tgaggaatct tggaagaatc actgaataaa gattgcatgc cttcagaacc aaatgctgca
    10801 ccgaaagttg ttcctaattc tttaaatgaa ttacctaacg aattcgtttg ccaatcaatg
    10861 gaacttaaat caacaacacc cataaaaata ccaaggactg tggtcgctac gataccgata
    10921 agaatagccc cacggacatt ttttacaact aaaatggctg tcagtaccaa accaatcaca
    10981 gccaataaga taggagcgtt gtcaaagttg gctaacgcag ggacgattcc accatttatc
    11041 gtaacatttg tcgcttttcc gccttcaacg acagagctcg aaatagctga ctggtctgct
    11101 gaaaaagata agaatcctgc atttttgatt ccgacatacg caacgaaaat accgatcccg
    11161 ccaccaatcg catgttgaag actttcggga atcgcccgaa taatcatttt tcgaatattt
    11221 gtgacagtaa taaaaatatt gattaatccg caaataaaca ccattgccaa ggcttgttgc
    11281 caagaataac caagcccaaa aacgaccgta aaagtgaaaa atgcgttcaa tcccatacca
    11341 ggtgcctgag catatggtac atttgcgaac aatcccatta ccagcgtacc aataatcgat
    11401 gcaatgattg tcgctagaaa tactgcttgg aagggcatac ctgatgctga caaaatcgtc
    11461 ggatttacga ataagatata actcatggca aagaatgtcg ttactcccgc cattatttca
    11521 gttgatacat ttgtattgtt tttctttaaa ccgaaaaact tttccataaa aagttccact
    11581 ccctgaattt ttttctgatg gaaaactata ataataaaaa ataagtaaaa tagggcaaat
    11641 ccatcgaaca atttcaaatt atatagacgt ttcattcgct tttcaacgtt tttttaacaa
    11701 aaaaagcgaa aataatactt aacgttcgtg tttagcttat gtttagctat ttatatagcc
    11761 ataactgtag tttttgttag gaatagctga ttgctcttgt taattaccta aaatatgcta
    11821 gactaaaaca aatgctagtt gaggaaggaa ggacccttat tgaataaaaa attaattgcc
    11881 atcgatctgg acggaactac cctcaatcaa gattcgatga ttacatctaa aacaaaagag
    11941 actctaaaaa aagcaatcaa tgccggtcat catgtcagta ttgctacagg acgcccattc
    12001 cgaatgagcc atcagtttta ccaacaatta gaattaacaa caccgatggt taattttaac
    12061 ggcgcattag tacacatccc taatcagcac tgggatggtg aaagagaaac gttgatcaat
    12121 cgtgaaatcg cttttgaaat cttatcgcaa aaaaagcagc taaatttaga ttttatcgct
    12181 gctgaaaatc gtgatacttt ttttattgac agttttgatt tctttgatga aaaaattttt
    12241 gcttcttctc gtccaggaga gaagaatttg ctttctccta aaaatttgac gacaaatcct
    12301 acatctttgc ttgtccgaac agacaaacgt tttgcaggag ctgtatctgc tgaattaaca
    12361 cgtcaatttg gcagttatgt cgatgttcgg acatggggtg gacctactgc catcttagag
    12421 attgtttcaa aaggaatcca aaaagcaaaa ggcgtgcaag agattgctaa ctacctgtct
    12481 atcgatcaaa aagacgtcat tgcctttggt gacgagcata atgatttgga attgttggat
    12541 tatgcaggtt ggggagtagc tatggctaac ggtactgacc aactcaaagg cattgcaaat
    12601 gatgtcactc ctttgagcaa tcaggaagac ggtttagctg tttatctgga aaaactactt
    12661 aaactataat agagaattag attccacaaa aaagaggttg tgacaatttt tgtcacaacc
    12721 ttttttgccg agtaaacggt gttcaaaagc cagtttctcg gtatgaagtc aa
//
LOCUS       DAIGQM010000074        12771 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.077, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000074 DAIGQM010000000
VERSION     DAIGQM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.077"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOA48_002301"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOA48_002301"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCI0790535.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="NOA48_002302"
     CDS             complement(2261..2512)
                     /locus_tag="NOA48_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCI0790536.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="NOA48_002303"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="NOA48_002303"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCI0790537.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="NOA48_002304"
     CDS             3462..3680
                     /locus_tag="NOA48_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790538.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="NOA48_002305"
     CDS             complement(3969..4481)
                     /locus_tag="NOA48_002305"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCI0790539.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOA48_002306"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOA48_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCI0790540.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="NOA48_002307"
     CDS             complement(6934..7377)
                     /locus_tag="NOA48_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCI0790541.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="NOA48_002308"
     CDS             complement(7378..8166)
                     /locus_tag="NOA48_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0790542.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="NOA48_002309"
     CDS             complement(8163..9104)
                     /locus_tag="NOA48_002309"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCI0790543.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="NOA48_002310"
     CDS             complement(9281..9868)
                     /locus_tag="NOA48_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCI0790544.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOA48_002311"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOA48_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCI0790545.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11699..12709
                     /gene="gap"
                     /locus_tag="NOA48_002312"
     CDS             11699..12709
                     /gene="gap"
                     /locus_tag="NOA48_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0790546.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3530 a         2858 c         2270 g         4113 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgtaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgtattaa ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat
    11701 gacagtaaaa gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat
    11761 caaagaagtc tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat
    11821 gttagcacaa ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc
    11881 aacagaagac tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc
    11941 aagcaaaatc ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt
    12001 ttatacatct gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat
    12061 ttctgcccca gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga
    12121 tgaaaacgac aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc
    12181 ttatttctta aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta
    12241 cacttccaca caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg
    12301 ttcagctgct gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt
    12361 tatccctgag ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg
    12421 ttcattaact gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga
    12481 agcaatcaaa aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt
    12541 ttctagcgat gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt
    12601 aacaactgct ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg
    12661 atttacttgc caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc
    12721 aatcgataaa agaagccttt gactggatcc agtcaaaggc ttctttcttt t
//
LOCUS       DAIGQM010000075        12638 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.078, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000075 DAIGQM010000000
VERSION     DAIGQM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.078"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            22..591
                     /locus_tag="NOA48_002313"
     CDS             22..591
                     /locus_tag="NOA48_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCI0790547.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            578..1438
                     /locus_tag="NOA48_002314"
     CDS             578..1438
                     /locus_tag="NOA48_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0790548.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            1628..2332
                     /locus_tag="NOA48_002315"
     CDS             1628..2332
                     /locus_tag="NOA48_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790549.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2337..4172
                     /gene="walK"
                     /locus_tag="NOA48_002316"
     CDS             2337..4172
                     /gene="walK"
                     /locus_tag="NOA48_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCI0790550.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4169..5485
                     /locus_tag="NOA48_002317"
     CDS             4169..5485
                     /locus_tag="NOA48_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790551.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5486..6355
                     /locus_tag="NOA48_002318"
     CDS             5486..6355
                     /locus_tag="NOA48_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCI0790552.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6410..7219
                     /locus_tag="NOA48_002319"
     CDS             6410..7219
                     /locus_tag="NOA48_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0790553.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7322..7951)
                     /locus_tag="NOA48_002320"
     CDS             complement(7322..7951)
                     /locus_tag="NOA48_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCI0790554.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8121..9413
                     /locus_tag="NOA48_002321"
     CDS             8121..9413
                     /locus_tag="NOA48_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790555.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9489..10151)
                     /locus_tag="NOA48_002322"
     CDS             complement(9489..10151)
                     /locus_tag="NOA48_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0790556.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10376..10660
                     /gene="groES"
                     /locus_tag="NOA48_002323"
     CDS             10376..10660
                     /gene="groES"
                     /locus_tag="NOA48_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCI0790557.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            10711..12336
                     /gene="groL"
                     /locus_tag="NOA48_002324"
     CDS             10711..12336
                     /gene="groL"
                     /locus_tag="NOA48_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCI0790558.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4207 a         2153 c         2750 g         3528 t
ORIGIN      
        1 atgaaaaaag gagcggttat gatggaaaaa atgcgtcagc aattaatgga gtgggggaag
       61 gaactagaaa cattccgtct gcctcactgg gaagaactcc ctgacttaga actttatatg
      121 gaccaagtca gaacgttagt tgatcgttat ctttcacctg tgatacaagg agaaaagcat
      181 ccattgctta cctcttctat ggtaaacaat tacgttaaac taggtttgat accagcacca
      241 gttaaaaaaa gatataacaa agaacacgta gcatttttac ttgcaatcac tacgttgaaa
      301 caagtattga ctattcctga aatcaaagaa gggatattgt tccaaggaaa aacagtagga
      361 attcgtgaag cctataatct attttgcgat gaacaagaag cagctgtgtg gatggtcagc
      421 caattagcac aaggtaaatc tcatccgcaa aaattcgacc aggcaacccc tgtagaatat
      481 attgctgtaa gagcggcaac tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt
      541 gttctagaaa ccgaatattt aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat
      601 tttagtagat tcaggtacgg atgtgccaga agaattgata aaaaaatacg agatgtatat
      661 gatcccattg aaaattattt ataaagatca ggtatataca gataaaattg acattacctc
      721 tgaagagatc tatcaacgtt tgccagagga aatccctggt acatctttgc cggatggtga
      781 gtcgatcaca gaaatctttg agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt
      841 aacaatttcc agtggattga gcgggacata taatgtggtt cgtttaattg cacaacagca
      901 agaagaattg gaagcatatg tactagatac gaaaaatatt ggtattggtg caggtttttc
      961 tgcgatccaa gcagcaaaat ggctggaaga aggagtagaa tgggatcaac tgatcagtaa
     1021 tctgaatgag ttagtcgaaa gaacaaaagt tttctttaat gttgcgacat tggaatatct
     1081 tcaaaaaggt ggacggatcg gtttagttgc ttctattgta ggaaccgctt taaagcttaa
     1141 cccaatcatc tcatgtaatg aagaagggat ttattacaca gtaggaaaag ctaggggacg
     1201 taaaaaaagt ttggataaaa cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt
     1261 cttcaactta gctgttgccc atggggatgc gaaagaagaa gcaattgaaa tggaagcgag
     1321 acttaaaaga gagttcccac aagcaaacca aatctacttt ggccagattt ctccggcatt
     1381 agtagtccac actggtccgg gattattggg tgtcggtgta caagttttag aaggataaat
     1441 caaaaaaagg aaacactgag gtgaaaatca gtgttttcct tttttattga agttagaaca
     1501 aaaaataata aagtattttg cactttcatt ttaattttct cttttgtttt ataggcaaag
     1561 atgaaacaaa agcagaaata cggtataatg agaaggtatg acaataatat ataagaggtg
     1621 gctctttatg aaaaaagttt tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa
     1681 attcaattta gccaaagaag gctatgatgt ttatactgca tatgatgggg aagaagcctt
     1741 ggaaaaagtt gctgaggtag aacctgattt gattttactt gatttgatgc tacctaaaat
     1801 ggacggctta gaagttgctc gtgaggtacg caaaacttat gatatgccga tcattatggt
     1861 aacagccaaa gattctgaaa ttgataaagt cctaggctta gagttaggcg ccgatgatta
     1921 cgtgaccaag ccattttcca accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg
     1981 cggtgccacg gctgcgaagg aaccagaaga ggcagcacct gcggaattga cgattggtga
     2041 tttgacgatc catccagaag cttacatggt gacgaaacga ggagaaacaa tcgagttaac
     2101 acatcgtgaa ttcgaactac tcttttactt ggcgaagcac cttggacaag tgatgacaag
     2161 agaacattta ttacaaacgg tttggggtta tgattatttt ggagatgtac gaacagtgga
     2221 tgtaactgta cgtcgtttgc gtgaaaagat cgaagataat ccaagccatc caaattattt
     2281 agtgacacgt cgtggtgtcg gttactattt gcgtaaccca gaacaggagt aattggatga
     2341 aaagaaaagt ccgctttttt cgatcagtca attttaagat cgctattacc tttattctga
     2401 ttttattgat ctcgatcgaa attattggtg cctactttat acgtggttta gaacgttcca
     2461 cgatcaatac atttattaaa gatatgaatc aaacggtgga atcattagca acaacaatca
     2521 gcccggaatt gaatcgaaaa gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa
     2581 gatttattga aaacagtgcg actagcgata tcatcgaaat acgggtcgtt gacgaaaaag
     2641 ggatcatccg aggaacaacc gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt
     2701 atgttgatat caatgatttc acgactaaac gttatgttgc tttagataac gacgataaac
     2761 gggtgaatat caatgttcaa ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc
     2821 tttacgtcaa aagtaatatc gaacaaaaat attcggaaat caataacaca gcagtcattt
     2881 tctttactgc ctcactaatt gcggcattta tttcaatgat cgtatctgtt ttagttgctc
     2941 gttcgattac acagccgatc ggtgaaatga gagaacaagc cattcgaatc gctagaggag
     3001 actacagtcg gaaagtcaaa gtgcatggac aagatgaact tggacagctg gctgatacct
     3061 tcaatcagtt agctgaacgt attgaagaag ctcaagatac aatggaagct gaacgcaatc
     3121 gtttggatag cgtgctatcc catatgacag acggcgtcat tgcgacagat cgcaggggta
     3181 aagtcattac gatcaatgat atggctgttt ccttgctaga tatcaaaaac gaggaagcaa
     3241 tcggacaatc gattttgaca cttttagata tcgaagaaga atatacgttg cggaaattat
     3301 tagaagatcc aaacgaaatg gtacttgacc gttcaaccag tacattggaa agtgatcaga
     3361 tgatcttgcg agtagacttt tctatgatcc gtcgcgaatc aggttttatc agcggattag
     3421 tagctgtctt gcatgatgtg acagaacaag aaaaaacaga acgggaacgt cgtgaattcg
     3481 tctctaatgt ttcccatgaa cttcgtacac cgttgacaag tatgcgtagt tatatcgaag
     3541 cattgagcga aggtgcgtgg aaagacgagg aagtagcacc aaattttttg aaggtaacgc
     3601 tagatgaaac agaccgaatg attcgaatga tcaatgacct cttaaatcta tctcgcatgg
     3661 atacaggtaa tacccagctt caattagaat atgtcaattt caacgagtta gtgaattttg
     3721 ttcttgaccg gtttgatatg atggtgggaa atcaggaaaa aaattataag atccgtcgtg
     3781 aatttacgca aagagatctt tgggtcgaag tagatacaga taaaatcatc caagtagtcg
     3841 ataatatcat gaataacgcg atcaagtatt caccagatgg gggaacgatt acttgtcgct
     3901 tattagaaac gcataataac gtggttttaa gtatcaccga tcaaggattg gggattccta
     3961 aaaaagatct gaaccgagtg ttcgagcggt tctatcgagt agataaagca cgtgcaagag
     4021 cacaaggtgg gacaggactt ggattagcta tttctagaga agtgattaag gcgcatcgag
     4081 gcgctatttg ggcagagagc aaggaaggaa aagggtcgac tttttatatc tcgctgccat
     4141 atgaacctta tgaggaggaa tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg
     4201 actcattttg atggttgcgt taagcatata cttctcttat gcaatctggc tgagcccagc
     4261 aggaaaaagt tcaatcaacg tagatgagac aaacactcaa atgatcgagt ctcaaagcaa
     4321 tcgaaaaact tccgaagtct ttcttccgct tcatgttaca tggcaccatt cgggaatgat
     4381 ccaagaaacc aacagtgaaa atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag
     4441 atttggaaag ctttctgaag tagtttcagg agacaaatca cagtttgaac aggtgaaaaa
     4501 tctgaactct ggttttgagt tggcctataa tgcgcctttt ttgctaagag aatacaagga
     4561 agcatttgat ttagatttag atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt
     4621 tactagaata caattcgatc aaggaaataa aaaaatccga tttttgaatt attcgaacca
     4681 tctcgtatat gaagcaaata tttcgttgaa ttggacagat atcaataaag aattaacagc
     4741 aaaagacaca aaatggacag aaatgacaac agaaccatcg acgatcgaca cgcaatatgc
     4801 tacgaaacat tcgatcaaac tgaaaaagta tagttatatc ctgtcacagc aaccctatac
     4861 actttttaga aatgcttttt tccagaaacc agatagcgtg aaaaataatg atgaaagcaa
     4921 tgaattgatt ttttacggtg ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt
     4981 tgattttcgt ggagagctgc cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt
     5041 cccctatatt agcaaattag gcagttcttt agggaacctc agatattttg accgcagtga
     5101 caatacgatc gattatcgga tattcgtgga aggcttcccg gtttttggga cagacagcag
     5161 aggacagatt ggtgtggaag ttggcggtga aacgaatggt tctgtgcaag tgaatatcca
     5221 aaccagtttg aatacgattc aagtgccgat accttcagac gaagaagtag aacttgcaag
     5281 tacgaatgaa atcatccagc agttaaaagc taagggagca gatagcaaca agattggttc
     5341 agtgatcgtt ggctatacat ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt
     5401 acctgaatgg tatgtgaaat ataaagataa ctggtattca gctaacgacc ttctggaaaa
     5461 attacctgga ttggaggcga attaattgga tttcaaaaaa atcgaatgga tatttttcgt
     5521 cgctttttta gggttgaatg tgtttttatt cagcagttat catgacgcgg tataccaaga
     5581 aaacaatgtc attcgctcta atcagactga atcaatccaa caacgtctgg ctagcgacga
     5641 tatcacttac acggggaaga tttcgtctga gaacaagcaa ggctattatc ttagcgcgga
     5701 gcagaccaat cttagcactt cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct
     5761 ggcaagtggt gtgtttttag acggtgatgt tttgacgaaa tctttatcca gttcagatgc
     5821 tgaaaagaac gtgatcgatc cagataaaat tagtagttcc ttggaagatt ttttatctaa
     5881 caaagacaat attttattcg gtaatgatta tgtgtacacg aaaaactttt ctcatttaga
     5941 agaagaacca ctagaaatcc aagcaagcca agagtatgaa ggcatcccat tcaatgatga
     6001 tacagcaaaa atcgttcttt ctttagaaaa aaacgataat gattatagca tcacgaaata
     6061 catgcagacg catttatctg atatcgagca gctgcgcgaa aagacggaac tgtatacgga
     6121 agaggaagca atcaatacat tgtacatcaa taacaaaata ccaagaggat caaaaatttt
     6181 atggcgtcag ctagcttatt cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc
     6241 tgtttggcat gtagcgatcg aaacaagcga taaagtggtc caaattgaga gtgtcaacgc
     6301 tttcagcaat acgatcgtga caaacaatac tgtaccaaaa gtggaagatc aataaaaaag
     6361 cgagtataat gaaaaaagtt tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga
     6421 aaaaccagct tttaaaatca gtatcctagc aagtggaagt tcgggtaatt cactttatat
     6481 cgaaagtgaa aaaaaacggc ttttggtcga tgcaggactt agcggtaaaa aaatcacttc
     6541 cttgatggct caaattgatc ggacaccgga ccaattagat ggaatacttg tgacgcatga
     6601 acatcgagat catatacatg gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt
     6661 tgccaatcag cagacttggg aagcgatgga accactgatt ggaaatgtac cagtggaaca
     6721 aaaacatcta tttgagatgg ggaaagtcag aacattcggc gatatcgata ttgagagttt
     6781 cggcgtctcc catgacgcag cggctccgca attttatcgt ttccataaag aaaatcggtc
     6841 attcgtcatg ttgacggaca ccggatattg cagtgattat atgcgaggtg tcattgaaaa
     6901 tgccgatggt tatttgatgg aaagtaatca tgatcttgag atgttacgca tgggacctta
     6961 tccgtggaat ttaaaacagc gtattttagg agatagagga catctttcca acgaagacgg
     7021 tgcacttgtc atgactgatg tgatcggtaa tcggaccaaa cgaatctatc ttggccatct
     7081 tagcaaggaa aacaatatga aagaacttgc tcatttaaca atggaaaatg ttttgaaaga
     7141 aaaagatttt ggcgttggac atgattttga aatctatgat acagatccag atgaagcaac
     7201 tgagctattt tcgatttaaa cagttcaatc aataaaaata taaaaagcag aagataaaat
     7261 caatcagggt tggttttatc ttctattttt atttttttag catattaaaa aaataaccgt
     7321 attatcgact gactacactg atgtgctgct tttcatgttt ctcatccagt atctcatcta
     7381 ctaatgcaat cgcgtaatct gccatgctga tcgtactgtc gccagcagcg tttctttgta
     7441 aataatcatc acttaacaaa taagtacctg tacgtttgcc atgtggatca aataaagaag
     7501 ctggactgat ataagtccaa tgtagatttt tagattgttt caattttaac aatccttcgt
     7561 acatattgaa agctgttgga tagaagggtg catttttagg tacttggtca atcatacgag
     7621 tcgtcttttc tgtatctaag aataacgaag aggcaccccc aacgacaatt aagcgtgtat
     7681 cggttccttc aagcatctca atcaaatggg acaaagaagt ttgatgcatt tcttcttttc
     7741 ctttgggagc gttgaaagca tcaacgacaa catcaaaaga tgcaagatca gtagttgtca
     7801 actcaaataa atccttttgt ataaacggaa catctgatgg caatttttct ggatgacgca
     7861 cgattgccgt cacgtctaaa tctctggaca atgcttcgtc taaaataaat gaacctgcat
     7921 ggccagtagc tccaatgagt gcaattttca taaaaaacct ccttttttat tcctgtccat
     7981 tgtaagcagt tgctgaatat tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt
     8041 cctttcatgg ttcgtgatca ttgggtatag ttaaattaag aaaactgatt gataaaaata
     8101 gaagttgaag gagataagaa atgaaagagt ggttagatcg tgccttttta ccaatgataa
     8161 catctgttgt gaatcttaga cccttaactg ctttgcgtaa tggaatgact tacacgatcc
     8221 caataattat tgttggctcg ctgtttttct tatttgctca ttttcctgtg gattacatcg
     8281 ctcagtggat agacaaaaca ggattttcta tgtattttac acaagtatac caggctacat
     8341 ttgatgtgat agccttttgg atcgtttttg ccattgcata cgcttatgca aaagaagaag
     8401 acatcgatcg cttaccagtc ggcataacag ccttgtctgc ttatctactg cttattcagc
     8461 cactaaatac tcagatagat actgtctgga caggtgctga agggatacta ggagcagtta
     8521 caactgggct catcatcgga tggggctatg cacgtttagt aagacttgcg aaagggtgga
     8581 agcaaagaga gaagatacct gaaaatgttt ggcagtcttt tacttcattg attccaatca
     8641 ttgttatagt cacttttacg cttatcggtt cagcggtttt tcaacagttg ttcagaatga
     8701 ctgttgttca aggagtatgg acatatgtcc agcttcccat tcaatcgttc atagacacgt
     8761 tgtttggtgt gcttttatta ggtttttttg ttccgttttt atggttattt ggtcttcatg
     8821 gatctgcgat ggtcaatggg ttggttagtc ccgtcttgca agcgaattca ttagcgaatg
     8881 cagaaatctt agcctcagga caagagttga cggtggcaaa tggcggacat atcgttactc
     8941 agcaatttct cgatcagttc atgacggtta cgggtgctgg attgacgtta ggggctgtat
     9001 tttttatgac ggtttttgcg aaatcgaaga aatacagaga attaggaaat cttgctcttt
     9061 taccagcctt tttcaacatc aatgaatcaa ttattttttc cacaccgatc gtgatgaacc
     9121 cgatgatggc tgttcctttt attttcgcac cggtcgtttc aggattgatt acctattccg
     9181 ctttatattt tggattcgtt cctttattta cagcagtcca agtcccttgg acaacaccgc
     9241 cgatcctctc gggtttctta gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt
     9301 tgtcaattag ttttttcatt tatttcccat ttttgaaaaa aatagattct gcaaactgca
     9361 aaaaggaaag acagacaaaa aatgatggag cagcagaaaa gatgaacgac taaaaaacaa
     9421 aaatactcct gtcgctttag attgggaaaa tcaccaatct aggatgacag gagtatttat
     9481 agtcatgttt atactagccc tttttggaca gctaattgaa caagaacaac taatgtgttc
     9541 attcctacgt gtgtgatcat cgatgtccag atccgaccag ttgctttgta ctctaggctg
     9601 aagaagaaac ctaggaaaaa gtagattagc agatgaccat cattatgagc aaacgcaaac
     9661 agcaaagagc tgatcactgc tccgacccaa aaatttgaat atcgactgat gatccccagt
     9721 atactgcggc ggaatacgaa ctcttccatg atgggtccag caacagttgt cgccaaaata
     9781 aaagcgggtg cttccatgat catctggatg atattttgtg tattctcgga aggggttgct
     9841 ttgccaaaca atacagattc taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag
     9901 attccaacca atccataaat aacaatcttt ggagcagaag ctttttttac cgctgattcg
     9961 atcgctaagg gttcacgttg cttaaaataa aaaatagcta ggacaacggc gcctagtata
    10021 tacatgactg cagttgctgt gatcaattca gacgtagatt ttacaagtcc tatcgaagct
    10081 aggatcaagg gtgagataaa aattagacca tagcaaaaaa tgctgaggaa gctatatttt
    10141 tttaaagaca tgtaattcct ccttttaagg gataacaagc atgcaaggca agcttatatc
    10201 gattgatttc aattatatca taatttcaat aagcagctgt cagaataaaa tttcttttct
    10261 ttgatttaaa agcttgcaaa aaagagggag aatgagtatt attaaaaatg taggttagca
    10321 ctcgaaggtt aagagtgcta acagattaaa aaaagagtta tcggagggat ttatcgtgtt
    10381 aaaaccatta ggtgatcgcg tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg
    10441 aggaatcgtt ttagcttctg ctgctaaaga gaaaccccaa actgggacag ttgttgcagt
    10501 cggtgaaggc cgtttgttag aaaacggtga aaaagttcct gccgctgtaa aagcaggcga
    10561 ccaagttatg ttcgaaaaat acgccggtac agaagtaaaa tacgaaggaa aagaatatct
    10621 gatcgtcgca ggaaaagata tcatggcgat tgttgagtaa atttggaaga taaaaaaata
    10681 atcaaaaata atcaatgagg tgaatcaatc atggcaaaag aattgaaatt tgcagaagac
    10741 gcacgcgcag ctatgttacg cggggtagat aaattagcag atacagtgaa agtaacatta
    10801 ggacctaaag gccgaaatgt cgtactagaa aaatcttacg gctctccatt gatcacaaat
    10861 gatggtgtga cgatcgcaaa agaaatcgaa ttagaagatc attttgaaaa catgggtgca
    10921 aaacttgtat cagaagtagc atcaaaaaca aatgatattg caggagacgg tacaacgaca
    10981 gcaactgttc tgacacaagc aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct
    11041 aatcctctag gcattcgtcg cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg
    11101 cataatatct caactgttgt tgattcaaaa gaagccattg cacaagtagc agctgtttct
    11161 tcgggttctg ataaagttgg acatttgatt gctgatgcaa tggaaaaagt tggaaacgac
    11221 ggtgtcatca caatcgaaga atcaaaaggg atcgaaacag aactagatgt tgtagaaggt
    11281 atgcagtttg atcgtggtta cttatcacaa tatatggtaa cagataacga caaaatggaa
    11341 gctgttctag aaaacccata tatcttgatc acagacaaaa aaatctctaa catccaagat
    11401 attctgccat tgttagaaca aatcttgcaa caatcacgtc cattgttgat tattgctgac
    11461 gatgtagatg gtgaagcatt gccaactctt gtattgaaca aaatccgtgg aacattcaac
    11521 gtagtagctg taaaagctcc tggtttcggc gatcgtcgta aagcaatgct tgaagatatc
    11581 gctattttga caggtggtac agtaattact gacgatctag gtttagaatt gaaagatgta
    11641 acaatcgaaa acttaggaaa tgcttctaaa gttgttgtag ataaagacaa tacaacgatc
    11701 gtagaaggtt ctggagaaaa agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa
    11761 attgctgaaa caacttctga ttttgaccgc gaaaaattac aagaacgctt agctaaatta
    11821 gcaggtggtg tagctgttgt taaagttggt gcagctactg aaacagaatt gaaagaatta
    11881 aaattacgca ttgaagatgc attgaatgct acacgtgccg cagtagaaga aggaatggtc
    11941 tcaggtggtg gtacagctct agtgaacgtt atcagcaaag tttctgctgt agaagcagaa
    12001 ggagacgtgg caacaggtat caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa
    12061 atcgctgaaa acgctggtta tgaaggatca gtgattgttg ataaattgaa gaacgtggaa
    12121 ctaggcactg gtttcaatgc tgctactgga gaatgggtaa acatggttga agcaggtatc
    12181 gtagacccaa ctaaagtaac acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg
    12241 ttattaacga cagaagcagt cgttgcagat aaaccagaac cagcagcgcc agcagctcct
    12301 gcaatggatc catcaatgat gggcggtatg atgtaagaaa aagcaacttg cttatctaca
    12361 actgatcatt agtgaaagac agataaaaag aggctggaac agaagcgttt aactccaaga
    12421 aataagaaga aattcacgga aattgctttt caaatttttg tgaatttcag cttatttccg
    12481 aaggagttgc ttctgcttcc gctgtttata cgtgtttaga gcgtgagaca aaagtgttct
    12541 ttacttttgt cccacgctct tttttgtgtg taattataat gaaaatagtt atttttaata
    12601 gttataatat tttatctatt aaaagtaaat atccattc
//
LOCUS       DAIGQM010000076        11344 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.079, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000076 DAIGQM010000000
VERSION     DAIGQM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.079"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(51..878)
                     /locus_tag="NOA48_002325"
     CDS             complement(51..878)
                     /locus_tag="NOA48_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790559.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKFLQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            1444..2679
                     /locus_tag="NOA48_002326"
     CDS             1444..2679
                     /locus_tag="NOA48_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI0790560.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(3678..3938)
                     /locus_tag="NOA48_002327"
     CDS             complement(3678..3938)
                     /locus_tag="NOA48_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0790561.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(3965..5266)
                     /locus_tag="NOA48_002328"
     CDS             complement(3965..5266)
                     /locus_tag="NOA48_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790562.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            5701..6660
                     /locus_tag="NOA48_002329"
     CDS             5701..6660
                     /locus_tag="NOA48_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0790563.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(6624..7082)
                     /locus_tag="NOA48_002330"
     CDS             complement(6624..7082)
                     /locus_tag="NOA48_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0790564.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLNFVCQIKLDKSSFVT"
     gene            complement(7095..8426)
                     /locus_tag="NOA48_002331"
     CDS             complement(7095..8426)
                     /locus_tag="NOA48_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCI0790565.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(8437..9879)
                     /locus_tag="NOA48_002332"
     CDS             complement(8437..9879)
                     /locus_tag="NOA48_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0790566.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(9866..10516)
                     /locus_tag="NOA48_002333"
                     /pseudo
     CDS             complement(9866..10516)
                     /locus_tag="NOA48_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
     gene            complement(10535..>11344)
                     /locus_tag="NOA48_002334"
     CDS             complement(10535..>11344)
                     /locus_tag="NOA48_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0790567.1"
                     /translation="KKLNHNAVLIDDDGIEKIAMGKGIGFSAKVSKPFDVEDADKLFV
                     LDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARISSPLDSNIYITLTDHIYFAIQR
                     KREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHRYQTELGSNEVGFITMHIINAEL
                     GEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLTYHRLMVHIKFLVKRLIYQEETP
                     VENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQENEIIYLAIHLARIY"
BASE COUNT         3685 a         2290 c         1744 g         3625 t
ORIGIN      
        1 ttttttcgaa taaacggtat tcaaatcaga acactgattt cacaaccact ttatttcagg
       61 tcgttttcaa tcacctttac cgcgtaatca tttccgttga aacgcgctat tttttttgcg
      121 tccatatatc tttctaaata atcatcttct cctaattgct tatggcaaga agcaatttca
      181 taaagcaagt attccaatgc ataagtcgat ttatgtttct tattatactc aatacccttc
      241 tcacataatt ggattgcttt atcataatcc tcgattttac ggtaataggt ggcgatatca
      301 taatatacaa tgcagaccat cagattatca aaatcagtct cactcaatat tttaagtgta
      361 cgctccacat aaactttcgc aaaatctaat tctccttttg acaagtagat cattgccacg
      421 tttgcagctg cttgtaagtg atggatatct gtttcggtcg tttgttccaa cacttgatta
      481 aaataaaata atgctgcatc tggttttttc gcataaagat gatcaagcag tccttgataa
      541 aataaaattt gatttaaaag atcagaatta cttacttttt cctgatcgat cgtttgtaaa
      601 aatttataag attcttggta ttttgataca gaattcaatg attgaatctc atttattttt
      661 ttcctgattt tgtcttcttc tgtttctact aatatatcgg agatctcgac attcagcttt
      721 ttgcaaagcg cacttaagat attgatgcct ggcgacatat tcttgttttc gatattgctg
      781 acagttgctt gttcacaaat gccttctgct aattgtactt gtgttaaccc ctttttcttt
      841 cggtattctt ttagtaatgc tccatctact ttaatcaaaa caatttcctt ccctttaaaa
      901 aattatttct cctttatatc atacacaaaa aaaagttcta aacaaccaaa aatgtttaga
      961 acagaataaa aattttaatt ttaaaataat attcaaatta aacaactggc gtatctgctc
     1021 cttgatttct ttttgtgtta tctgaataat tatcgtttac agttataaca catagtgaaa
     1081 attgtcatgg cgagaaagtc taagaatatt tttaaacata actatttctt tcttacgtgt
     1141 ataatgacga cagcacacct atcaattaat ataattattt tattttttta tgttctcatg
     1201 tttattttta atgacacaac ttctcgtatt tatctggcac aacatataaa tcgatcaaaa
     1261 aattgttgcg tgtttttttg aaaattggag tttcaacttg attacaaaat ttaaatttag
     1321 aagttgtgaa aacagcgaga gacagtttaa tattcaaaat atacataggc tactcgaacg
     1381 ctgtgttttt tagtatacta gtaagaaacg aagggataga ctcattccaa taaggaggat
     1441 ttcatgaaga caattctttt tgctcctgca gtattcaatt tagctgagac aacacgaatg
     1501 attgaggttg ccaaagctat gaaagaccgt tattactgtg tattctttgg cttttctaaa
     1561 acttttgctc ctttgatcac agaaagtggc tttgagtatc atttactagc gccgatcctt
     1621 acgaaaaaac aagaagaaca aatcataaaa tttgaccagt tgcgtacact taaaaaccct
     1681 tttaccaaag aaatggttgc ctctcgtatc actagtgaac agagtctgat tgctaagttt
     1741 gagcctcgac tgattgtgac aggttcgaat gtgacaattt ttttatcggc ccgcaataaa
     1801 aagattcctt tagtatatgt taaaccctat gctttgagtg aacctttttt tcaatcagag
     1861 catgcgctga tgccccacga gttacgtttc ttcggccctt taagcaatcc cctttggcac
     1921 tggacaaaaa agcgtatagt aaatacccga tggatcccca atgccttcaa acacgctgca
     1981 caaaaagaaa tgcttccttt accaaaaaca agtttacaaa tgatggatgc tgatctaaat
     2041 ctcatcacaa cgcctaaact atttttggaa gaagaacagc tgccggaaaa ttatcgaatc
     2101 gttggtccaa tttttgctaa gctcagtact tccttgcctg aagaagtgct aacttttata
     2161 cagcgaaagc aacaagaaag aaaacgtatt atctatttcg caatgggtag ttcaggcaat
     2221 ccgcgtatgt tacgcaaaat tttgttcttc ttacaaaaac aaccggatct agcggttatt
     2281 gcacctattg actatctgct tgatgacatt caatctgact cagaagatct tttaataaca
     2341 gaatatctgt ctagtcatct tttgcatgaa ttcattgatt tttcttttat ccacggcggg
     2401 gaagggaccg tccaaactgc ctgtgaatcc ggcaaaccgt ttatcggtgt ggggatgcaa
     2461 tttgagcaaa gctgtaatat tgactattgt gtaaaatacg gaaacgcaat cgccctcaca
     2521 aaaccagtga ctgaaagaaa actgcagatt gctctgcgcg aagtttcttc acccaagatt
     2581 cgtcagcagg cacgcacgct gcaagccgtt tttccaataa atggtccaca acaagcaatt
     2641 caagaaatcg aaaccttcct gagcaaccac ccaatatagt ttcaagtaga aaaagctttt
     2701 ttaatagaga ctcatcagta atttcgctat tcgagaccca gacagtgaaa atacaaaaaa
     2761 agtaaatagt ggattgaaaa gttagagtta cttaaattac ggtgtctaaa aaacacaaaa
     2821 tcatccttaa aataaaagat ctgacgctat ccaaatgagc ataggtagcg tctgccattt
     2881 attcttagtc aaattctttg acacctttct ctggttggat catctcaacg tttcttcaaa
     2941 agaaagacca taataattag gcaaatacat tttcttaaaa tgtgtcatat agatctagaa
     3001 gcatcgcttt gtagagattt gtgccgctag tcccctcaac aattactaaa tcaaatgtag
     3061 gatttaccac tttatctttg ataatcaacc tccctcttct gttgagacaa tgatctcgca
     3121 atccgatgca tactcctata taaactgcca gcaatcccca catattgagt agatcatgtc
     3181 agaatgttct atgtcgtcag caacgataca ctaaaagtca cgttcaccat gactgattgc
     3241 tattcccagc acaattattt ctatacacgt ttcatgattt gaataaacac tcacatcata
     3301 catattacca ttcatacacc atactgcagc ccctactata tggttgtaag ctcccaaatc
     3361 tatatttgac ttgatcactt tggtagtaga tctactaatt ctaaatccat tgctgataaa
     3421 atttccattt tttcctcctt ctttctgcca aaacagttaa aacaataata atctttatgt
     3481 aaaaaagggc tgtgacaaaa gccttgtcac agtcccatat tccgaataaa cggtggtcaa
     3541 aagcttgcat ctgcggtaat aagttcaacc aaacgaaaaa taagccaaca tttcacaaaa
     3601 atttaagaag caattttcgt aaatttcttc ttatttcttg aagctaacca cttctgttac
     3661 aaccactttt agaacattta aagcttcgat gtgacaaacc atctatgctg ctcgatcata
     3721 aaattgatag caaaaattcc acaaagtaca tatgtccccc atgaaaacaa aacattcata
     3781 tgcggtacaa tgatctttgg aagaatcacg atcaaaaatg atgccagtgc ccaaatccat
     3841 cgattgattt gaatatgata tgtagctagc atattcaata taaggtgact agccgttaat
     3901 aaaaagataa aaacaaaaaa taaaatcagc caatacattg tttcccacct tctaaaaacc
     3961 aaacttagac agtctggact tcgttttctc cacgactttg ttcatctgac agcatctttt
     4021 tatcataagc ttttacaaat ggataataga taataaatgc tatcaatgtg ttgatcatga
     4081 tcaagataac aacacgccag tcatttcctg ctgaaagata accgccgatt ggagctggta
     4141 atgtccatgt tggcaaaaca gtaaatctat tgaccatttc taatttgact gcaaaataac
     4201 tgataatagt caaaactaaa ggaactaagt tgaacgggat gaacatgtaa ggattcaaca
     4261 tcataggagc tccaaaaatt atgggctcat tgatattgaa gataccagga ataatagaaa
     4321 aacgaccaac ctctttcaag aattttgatt tacagaagaa tataaacaaa acagatacca
     4381 cgatcgttgc tcctgcacca ccaattgtta ccgtccattg ataaaactgt tcaggagcga
     4441 tatagggtaa ttgggtggca gctgtaccat ctgccaatgc ctttgcattc tcatccaaca
     4501 tgatcagcca cattggacga acaacagccc ctacaatact catgccatgg ataccaaatg
     4561 accacaacaa atggatcaaa aacattggta gtaaaacacc aagcaaatta ttccctaaaa
     4621 tattggttaa aggctcgaat aacgataata aggcagcgtt tacatcaaag cccgcgacgc
     4681 ttcgaatcag ccaagtaatt gttaaaatga ctgcacctgg aatcaatgcc tcaaaactac
     4741 gggcaacagc aggtggcact tgttctggca ttttgatagt aatatttcga tttttaaaga
     4801 aacgatatac ttccactgca aaaatcatag ataagatccc cgcaaacatc ccagatgctc
     4861 ccaaagaact cataggtaag acccagccaa gaggtgcctc ttcaggagtt aaaacgttta
     4921 caggaacttg taacataaag aacgttccta aagataatat accacctgtc acactatcta
     4981 atccatatga tttagctaga tccgaaccca taacaaaagt tgcataaata gccatcaatc
     5041 ccatcgtcat cctaaagggt aaaacaatcg ttgccgaata aggggcaata aattcattcc
     5101 atccaggaaa cggtaaattg ataaagacca taaaaaatgt cccaatcaaa atcaatgaca
     5161 atgttgaaac aaccccatta cgaattgcta ataaatgacg ctgtgtacca atttttgcca
     5221 ttggtgggac aagtttctct tcgacccatt tcatcagctt ttccactaaa accactcctt
     5281 ttcaataaaa tatgaaccat tcattgcatg acaacgcaaa gaatgttcat aactaattat
     5341 ataattaaga aattttattt caatatattc tcttaaataa tcaaatttat ttttaagaat
     5401 cctgaaaata agttttctaa atcataggag caacaaaaaa attcgataat taacaaaaat
     5461 caaaatgatt aaatctagtg attgaaacat atcatttcaa aaaaattttg taaattcacc
     5521 cataaatatc accctattta acttttttca tcgtacacta aaattcaaaa caactatctt
     5581 taatctttac ttcttggttt tgttttcgcc gattgtaaaa ttaagctaga caactaaaaa
     5641 aagtcatttg tgctacactc aaaatagttc cgacgaaaga attataagga gtgagtacaa
     5701 atgacctata accatcttac accaactgaa ctcgtaatga tagaagctta tttcaatcaa
     5761 tcacaacctg tttcaaaagt agccaatctg ttacaacgtt ctcgacaaac tatttataag
     5821 gtctatcgtt ttcttaaatc tggtggaagc gcaatgagct actataaaca atataagaaa
     5881 aacaaacgta actgcggaag acatccgatt gttttacctg atgagcaaca ggaatacatt
     5941 caaaaaaagg ttgttcaagg gtgggctcct gatgtcctta ttggtcgagc agagtttcct
     6001 attgcttgtt cggtacgcac actgtatcga atgtttaaag ataaaacctt tgacactcac
     6061 gatttaccaa tgaagggaaa aagaaaacca aacggtcata aagaaaaaag aggaaaacaa
     6121 gggtttcgcc ggtcaatccg agacagaaag acagactata cccagtttga tcatgaattt
     6181 ggtcacctgg aaggtgacac tatcgtgggt ggaaaacata aaagcgcggt catcacatta
     6241 gttgaacggc tatctaaagt catcattacc ttgaaacccg aaggcagaca ggctaaagac
     6301 attgaaaata ggctgaatca atggtttcgt tgtgtcccaa aaaacttatt taaatccatc
     6361 acatttgatt gtggaaaaga attctcaaat tggaaaaaga ttagtaatac caacgatatt
     6421 tcaatttatt ttgcggatcc aggaacacct tctcaacgag gattgaatga acattcaaat
     6481 ggcttattac gtaaagatgg tttgtataaa gctatggatt ttaatggtgt atctgaaacc
     6541 tttatccaat cggtggcatc gaaacgaaat catattccta gaaaatcatt acactatcgg
     6601 acaccaatgg aagtattttt gagttacgtc acaaaagatg atttgtctaa cttaatttga
     6661 caaacgaaat ttaataaatt tccttcaaaa atgcctggag aaactacaat gatcaccgta
     6721 tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt cccttctttt
     6781 acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc aactgtatct
     6841 aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat ggcatgtcgg
     6901 gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc atcatgattc
     6961 gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt tactgctgtt
     7021 aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt aaagaaatgc
     7081 actttttatc acctctactt taatgctggc caatattttt tgtttacttt gatcatttca
     7141 tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt aaatgcttgt
     7201 aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc tactgcaact
     7261 tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt aattggctcc
     7321 acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg tagattcgga
     7381 atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt caacaaggaa
     7441 atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa tacttcttcc
     7501 acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg tccatccatg
     7561 accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc aggatataag
     7621 taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat gactgacatc
     7681 atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac ttgcatttct
     7741 tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc tttatcataa
     7801 atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca attcttacga
     7861 tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc acaggcatta
     7921 atcattttta cattcggata tttacgacga acagcttcag aaacgatcga ctctggattt
     7981 gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac aatttccaat
     8041 aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt ttcttgtcct
     8101 actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa tcctccaaca
     8161 cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc atccgttgca
     8221 cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat caagtacata
     8281 tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt
     8341 tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata
     8401 gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa
     8461 ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg
     8521 tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc
     8581 cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc
     8641 tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa
     8701 ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt
     8761 ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa
     8821 aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc
     8881 aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc
     8941 tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact
     9001 aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat
     9061 tcctttgacc atctctttat tttctttata agctgcttta tagatagcta gacatatagc
     9121 tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag cctgaggatc
     9181 tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct
     9241 tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa
     9301 acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga gcagttttgc
     9361 aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa cagctgcgat
     9421 tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac
     9481 tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat
     9541 aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc cttttttcaa
     9601 ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa
     9661 accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc
     9721 tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga tcaatcccgc
     9781 taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt
     9841 aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag
     9901 gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgggtac
     9961 gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca
    10021 tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca
    10081 cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct
    10141 caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat
    10201 catatttttt tgctaatgta acaactacct cctgattttc atccaaagta tgagtatgat
    10261 gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat
    10321 tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg
    10381 atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt ttgccacacg
    10441 tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcat
    10501 gctcgaaacc cggcatgata gttacgccct tattttaata gattcttgct agatgaattg
    10561 ccaaatagat gatttcattt tcttgaatgg caagttgaaa ttgctgttcg atgatatctt
    10621 taatctttag tgctgtacaa tacgctttgc tatgtttaaa tgtttcagta aaaaaaccaa
    10681 tattttctac tggcgtttct tcctgataaa tcaagcgttt aaccaggaat ttgatatgaa
    10741 ccattaagcg atgataagtc agtgattctt tatcataaac gtttgaatag gatttttcta
    10801 gatgggacaa aatcgtggtc gtcatttcta ctatttttaa gctctttaaa ctattaggct
    10861 ctcctagctc agcattaatg atatgcatag tgatgaatcc tacttcattt gaccctaact
    10921 cggtttgata tcgatgattg attcgctcga ccacttctac tgctatatca tattcatttg
    10981 gataaaggaa tctcatttct ggcaacataa ttgctgtgac atctctatct tctctttttc
    11041 gttgaatagc aaaataaata tgatctgtca atgtaatata gatatttgaa tctaatggag
    11101 aggagatcct agctgttatc agttcaatca cttcttccgc aaaatccata aattcgattg
    11161 gaatctgcga gactatctca ctgaatcgtt tgatcttttc tttagaatct aatacaaata
    11221 atttgtcagc atcctcaaca tcaaatggct tactcacttt agcagaaaag ccaatccctt
    11281 tccccatcgc aattttttct attccatcgt catcgatcaa tacagcatta tgattcagct
    11341 tttt
//
LOCUS       DAIGQM010000077        11253 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.080, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000077 DAIGQM010000000
VERSION     DAIGQM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.080"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOA48_002335"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOA48_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCI0790568.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOA48_002336"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOA48_002336"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCI0790569.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="NOA48_002337"
     CDS             complement(2169..2906)
                     /locus_tag="NOA48_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0790570.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="NOA48_002338"
     CDS             complement(2997..3524)
                     /locus_tag="NOA48_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790571.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="NOA48_002339"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="NOA48_002339"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCI0790572.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="NOA48_002340"
     CDS             complement(4401..4886)
                     /locus_tag="NOA48_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCI0790573.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="NOA48_002341"
     CDS             complement(5039..5236)
                     /locus_tag="NOA48_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790574.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOA48_002342"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOA48_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCI0790575.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOA48_002343"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOA48_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCI0790576.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="NOA48_002344"
     CDS             9211..9423
                     /locus_tag="NOA48_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCI0790577.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="NOA48_002345"
     CDS             9425..11104
                     /locus_tag="NOA48_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0790578.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAIGQM010000078        10800 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.081, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000078 DAIGQM010000000
VERSION     DAIGQM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.081"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            185..1183
                     /locus_tag="NOA48_002346"
     CDS             185..1183
                     /locus_tag="NOA48_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0790579.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="NOA48_002347"
     CDS             1295..1804
                     /locus_tag="NOA48_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCI0790580.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="NOA48_002348"
     CDS             complement(1833..2492)
                     /locus_tag="NOA48_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCI0790581.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="NOA48_002349"
     CDS             complement(2494..3258)
                     /locus_tag="NOA48_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCI0790582.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="NOA48_002350"
     CDS             complement(3266..3943)
                     /locus_tag="NOA48_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCI0790583.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="NOA48_002351"
     CDS             complement(3980..5365)
                     /locus_tag="NOA48_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0790584.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="NOA48_002352"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="NOA48_002352"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOA48_002353"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOA48_002353"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCI0790585.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="NOA48_002354"
     CDS             6304..7161
                     /locus_tag="NOA48_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790586.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="NOA48_002355"
     CDS             complement(7242..7577)
                     /locus_tag="NOA48_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790587.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="NOA48_002356"
     CDS             complement(7644..9014)
                     /locus_tag="NOA48_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCI0790588.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="NOA48_002357"
     CDS             complement(9092..9628)
                     /locus_tag="NOA48_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0790589.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..>10800
                     /locus_tag="NOA48_002358"
     CDS             9937..>10800
                     /locus_tag="NOA48_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790590.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFL"
BASE COUNT         3285 a         2185 c         1753 g         3577 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgcttttg gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
//
LOCUS       DAIGQM010000079        10651 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.082, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000079 DAIGQM010000000
VERSION     DAIGQM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.082"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            23..646
                     /locus_tag="NOA48_002359"
     CDS             23..646
                     /locus_tag="NOA48_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790591.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="NOA48_002360"
     CDS             1096..2145
                     /locus_tag="NOA48_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0790592.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="NOA48_002361"
     CDS             2142..3023
                     /locus_tag="NOA48_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790593.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="NOA48_002362"
     CDS             3026..3796
                     /locus_tag="NOA48_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0790594.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="NOA48_002363"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="NOA48_002363"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCI0790595.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNGTDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="NOA48_002364"
     CDS             5107..6270
                     /locus_tag="NOA48_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0790596.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="NOA48_002365"
     CDS             6387..6797
                     /locus_tag="NOA48_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0790597.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="NOA48_002366"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="NOA48_002366"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0790598.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="NOA48_002367"
     CDS             9370..9654
                     /locus_tag="NOA48_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790599.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="NOA48_002368"
     CDS             9814..10050
                     /locus_tag="NOA48_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0790600.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="NOA48_002369"
     CDS             10047..10445
                     /locus_tag="NOA48_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0790601.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3718 a         1772 c         2253 g         2908 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgga
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaaactaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat t
//
LOCUS       DAIGQM010000080        10590 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.083, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000080 DAIGQM010000000
VERSION     DAIGQM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.083"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            108..311
                     /locus_tag="NOA48_002370"
     CDS             108..311
                     /locus_tag="NOA48_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0790602.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(412..1074)
                     /locus_tag="NOA48_002371"
     CDS             complement(412..1074)
                     /locus_tag="NOA48_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790603.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(1087..2589)
                     /locus_tag="NOA48_002372"
     CDS             complement(1087..2589)
                     /locus_tag="NOA48_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790604.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3137..4816
                     /locus_tag="NOA48_002373"
     CDS             3137..4816
                     /locus_tag="NOA48_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0790605.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            4943..5422
                     /locus_tag="NOA48_002374"
     CDS             4943..5422
                     /locus_tag="NOA48_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCI0790606.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            5641..6321
                     /locus_tag="NOA48_002375"
     CDS             5641..6321
                     /locus_tag="NOA48_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCI0790607.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            6329..7660
                     /locus_tag="NOA48_002376"
     CDS             6329..7660
                     /locus_tag="NOA48_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0790608.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            7675..8637
                     /locus_tag="NOA48_002377"
     CDS             7675..8637
                     /locus_tag="NOA48_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCI0790609.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            8748..9086
                     /locus_tag="NOA48_002378"
     CDS             8748..9086
                     /locus_tag="NOA48_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCI0790610.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            9165..9872
                     /locus_tag="NOA48_002379"
     CDS             9165..9872
                     /locus_tag="NOA48_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCI0790611.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(9975..>10590)
                     /locus_tag="NOA48_002380"
     CDS             complement(9975..>10590)
                     /locus_tag="NOA48_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HCI0790612.1"
                     /translation="STSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVF
                     FELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLI
                     QHLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQH
                     EKISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3392 a         1883 c         2250 g         3065 t
ORIGIN      
        1 acagctctaa ctatcttttt tagaaaacga gcgttctgtt tgtctgtatc tgttgttgat
       61 gttaccctga aggtagatca ataaacaaac taagaggagg aagcacaatg gcagatttaa
      121 aaggacgttc taaagatatg aaagataaag tagtcggtga aggaaaagaa gcatacggca
      181 aagcaacaga cgacaagagc aaagaaacag aagggaaagc acaatcacta ggtgctgaca
      241 tcaaagaaaa agctcgaaat ttaggcgacg aagtcaaaga caagttttct cgaaaagacg
      301 aaaaaaaata aaaaccactt attactaatt gaatcaagca aataaaaaat ccgaaccata
      361 tctgcgagac agatatggtt cggatttttt atttgatcat tatcctgttt tttaaacttc
      421 gattttttga aattttttat tttttagttc aaagacttca tcacagcttt ttgctacttc
      481 aatctcatga gtcacgatga taatacagcg attttgttca tgggcgattt cttggaaaag
      541 tttgacgata tcttgtgaag ttgtttcatc tagatttcca gtaggctcat ccgctacgat
      601 tagttgatgt tcacagcaga tagcacgaac gatagcgact cgctgctgct gacctcccga
      661 aagtttggtc acctgttttt ttgctaatat ttcatcaatt cctacacgag ccagtcgatc
      721 taaagcaact tgtcgataat tctcttgctt ggtcttagtg atttccattg ctgctatgac
      781 gttgtctaga gccgataaat aaggaagcaa gttgtaagct tggaaaataa tcgagacatc
      841 atttttacga taacttctta acccgatttt gttcagtgaa cgatcttgat agtatacctt
      901 tccttctttt ggtgcatcta gtccagaaat aagcgaaaga aaagtcgttt ttccagaacc
      961 acttgctcct aaaatagcgt acatttttcc agcttcgaaa ttcagttcta catctttata
     1021 aagcgcatct tgcggatctt gataccaaaa tcccaattgt tctgtccgta acatcaaatt
     1081 cctcctttag tttaatagga tttttcttgg gtttaatctt aatatcccta tagaagctaa
     1141 aaagacagaa aacagactga ttccaaatgc tactccggct aatagtccca attgtgcagg
     1201 tttgacattg atttccaatt cgctgacttg atcagaaaca gcaaatggat tattcgtggt
     1261 tccttgttga ccatcgcgtt gaccgccttg ttcttgtctg ttacctggca tttgtccacc
     1321 gccaggagct tgctggtttt gtgtcgtggt ttctgtctgt tggtcaagta gctgctgtcc
     1381 cacggcattc gcgacgacgt ttccgctaag cgaagcaact cctaatgcaa gaatcataca
     1441 aatagccact tcggtaaaca attggagaat gattttactt ctggattctc ctaaagatag
     1501 caagacgcct aactcatgcc gacgctcccg aatggtaatc ataatgatca gagtaagtat
     1561 gataataccg gctacagcca ctagtaaaac aacattttta gaaaaacttg ccacgttgtt
     1621 taaaggttcc aacattgact gatacatgga atcatttgat tgtaagctaa atgtatctgt
     1681 gtcgatcagc ttctcagctt ctttgagaaa ctcatccatt ttatctggat cagatagagt
     1741 gtaaatagca gaatctatcg tgttatcgtc agatgtccca tttagttcat ttgcaaaagt
     1801 gtaagaagtg taaagtgtat tcgacggatt catgaagttg aatttcatac ccatactgcc
     1861 gcttgtttcg ctggattcat aaattccttt gatcgtcatt tcataagtgg tatcttcatc
     1921 ttcagtactc gtgattgtga aagtatctcc gactgccagg tcatttgttt ctgctagagt
     1981 agaatcaatg actacattgt ttgtgccttt gtcgctgtca tctattcctt caccatccgt
     2041 gatttttgct gttccatcag aaaaattact attttgtgca gttgctgaca caccactgat
     2101 ttgaaagtct gcttgagtca tttgcggatt cccgcccatt cctccagcag gttcaccgcc
     2161 tgcatcagta gtttctgaac tgtcttcact tgaatcagaa ctagtgatgg cagttattcc
     2221 atcttttgcc atagctgagg cggaactttc aaaggaataa ctctttacat tatctaattc
     2281 agctattttt tccgcgtccg ttaaggaaac tggtgtaaga gaaaaactgc ctggatctgg
     2341 acgttcttca gtggtagaac cgcttgaaga agtttgttcc tgttttttaa atgaagcttc
     2401 tcgattggca cttaaagtca ctgttgctcc aacttctttt tgtgcttgat tcgctgcttc
     2461 ttctgcagcg cttcgaatcg tgaggccagc tagcacaaaa ataagaatgg ctgtgaacac
     2521 ggcaaacaat aacaatgaac gtccccattt tacttttgta cttttccatg cacgtttcat
     2581 aaaattcata ttttgcatcc ctcctagtag atgcatttga taatagacaa cctatcttaa
     2641 agctagctta aatcttatgc tgtttgcaca ccatcaacat gaggttctgt atatataaaa
     2701 agtcactata gttattgcaa aaaatgtggt aaaatgaaaa aagtatgttt caaaccgacg
     2761 aagaagaaat gaaagaggaa tagcaaaaga aatcctagat gctacagagg gatttttacg
     2821 tgcatagttg ttctaacaat tgctgatact agcgatttag tttatttgtt gtataataat
     2881 ggggaacagc tgaatactta tataagtatt ctggctatag cgtttcgcaa aagatccatt
     2941 ttgttaatga agtatatcca aaataaaatg cccatccaac tgtcagaacg cggatgtgct
     3001 ggtaattttc ctgctgattc tccataagtt gagaaatagt gattttgcat atgcttcatt
     3061 ggaatggctc atatatttag ataaagaaga aaatcgacat ctttaaactt ggatgtcata
     3121 agaagaggtg aagtttgtga gtaccattaa aattatccca ttaggcggcg ttcgtgaaaa
     3181 tggaaaaaac atgtatgtcg cagaagtggg cgaggatatt tttattttag attgtgggct
     3241 aaaatatcct gaaaatgagt tgttggggat cgacgtcgta atccctgatt ttacgtattt
     3301 agaagaaaac attgatcgtg tagctggtgt ctttttaaca catggacatg cagatgcgat
     3361 cggggcactt ccttacttgt tgtcaaaaat ttctgtacca gtattcggga cagagttgac
     3421 gatcgagtta gcaaaattga atgtcagtcg taatgaagca gccaaaggat ttaaggattt
     3481 ccatgtggta gatgagcata cagaaataga ctttggtgaa acagtagtga gctttttccg
     3541 taccactcat acgataccag attcagtggg gatcaatctg aaaacaaaag aaggtagtat
     3601 cgtttatacg ggagatttta aatttgacca aacggctatc ccaatgtatc aaacagatta
     3661 tgcacgattg gcggaaatcg gcaaagaagg agtcttagcc ttactaagtg aatcggcaaa
     3721 tgcagaaaat cctcagcctg tagcttctga agcccaaata gcagatgaag tatttgatac
     3781 gatcaaatat tgggaagggc gtatcatcgt cgcttgtgta gcaagtaatt tgcaacgagt
     3841 gcaacaagta ttggatgcag cagaaaaagc acaacgaaaa gttgtcttga ctggtcaaga
     3901 tttcgaacga attattcgca cagcgatgcg tttagaaaaa cttcaattac caagtgaaga
     3961 tctgcttgtt acgttgaaag acatgaaaaa ctatgatcca gaagaactga tcattttaga
     4021 aactggccga atgggtgaac ccatcaagtc tctgcaaaaa atggcaaacg gtacacaccg
     4081 taatgtcaag attgaagaag gagatttggt ttatatcact actacgccaa gcatcgcgat
     4141 ggaaaccatc gtggcgaaaa cggaagatat catttatcga gctggtggaa cagtgaagtt
     4201 gatctctgag aatatgcgcg tttctggcca tgccaatcct aatgacttgc aattaatgat
     4261 caatttgatg aaaccaacat attttgtgcc agttcaagga gagtatcgtg aattagctgc
     4321 tcatgcagat ttggctcatg cagtagggat gccatacaaa aatatctata ttactggacg
     4381 cggagacgtg ctggaatata agaacaagcg tatgagtgtt gcaggaacta caagtgcaga
     4441 aaatgtaatg attgatggat taggcatagg tgatatcgga aacattgttt tacgtgatcg
     4501 aaaaatcttg tcagaagacg ggattttcgt agcggttgtc actatcagtc ggcgagaaaa
     4561 gaaaatcatt tcaaaacctc aaattacttc acggggattc gtttacgtaa aagctagccg
     4621 tgatctgatg aaagaaagca gcaatatgat tgaaacaatc gttgagaaac atttagaaag
     4681 caatgatttt gagtggagca aattaaagca agacatccga gatcaattag gccgttactt
     4741 atttgaacaa acaaaacgcc gcccagtgat cttgccagtc attatggaag ctactcaacg
     4801 tcgaaataaa aaataaacaa aaagagtaag atgaacctct ctatagagtg ctcgtcttgc
     4861 tctttttttg cgaaaaacaa ataatttttg aatacagcat ccctcgcttt ataataaacg
     4921 atagaataaa gggagtgaat caatgatgag tcaaacaaaa gtcgaacgtt atttagaaga
     4981 acaaaagatc agctatcaac cacttgattt tagtcatgtg gtagaagaat ctttcacaga
     5041 agaactacaa aaaagaggga ttgatccagc tttgatatgt aaaactctcg tagtgaaagg
     5101 aaacaaaact ggggtgatca tcgcattgat tcctttgaac gatcacttag attacaaaaa
     5161 aacgagacaa gtgacgaaag atcgtaaagt tggttttcct ggaatggatt ttgtattaat
     5221 gcatacagga tatccccacg gagcaaacac ccctattgga ataaaactcg cacatcctga
     5281 ttattgtttt ttagcagaca gttctttaaa agaaaaagaa gaagtaattg tgtcaagcgg
     5341 tgaaatcggg agaagccttc ggataaaagt agccgattta gaaaagatcg tccatcctat
     5401 ttacgctgat ttaattagtt aagggacgag aagagaagct aagcagagca gagacctcaa
     5461 acttgagatt atatctgctt ggtacttggt gcatcctgta ttatctgtta caattgcttt
     5521 gtacatactg tactatcaat ccaatgaaaa tatatttagc agctatattt tttcattgat
     5581 gtgcaagtga tgaaatcgtt tttaataaaa aagatacaga gaaaacgcga ggtgtaaaat
     5641 atgaaaatta cgtatcatgg acattcctgt ttaacaattg aaatggaaaa tggccaacgc
     5701 gtgatgattg acccgtttat tacaggaaat ccattgacag acttaactgc agaagaagta
     5761 aagacagatt ggttgctgat tactcatggt catagtgacc acataggaga tatgattcct
     5821 attgcaaaag aaaatcaagc cacaattatc agtattgttg agattgctga ttatgcgaac
     5881 agcagaggag tagattcatt cggtatgaat atcggtggaa aacatgcgtt tccattcggc
     5941 gtggtaaaat tcgtacatgc acagcatagt tcaagctatg aagtagacgg tatcgttcag
     6001 tatatgggcg agcctagcgg aattattatt caagcagaag gaaaaacgat ttatcatgca
     6061 ggggatactg cttatttcag tgatctagga ttgcttgcag aagaattcga tattgatgtc
     6121 gctttcttgc cgattggcga taactatacg atggggccag aagatgcagc aaaggctgcg
     6181 caaacaattc gtgccaagaa agtagttcca atccattaca atactttccc tgtcattgaa
     6241 caagatcccg aatcttttgt agagttactg gaagatagtg aaggaaaaat aatgagcgtc
     6301 tcggaaacgc tggaagtgta ggcagaaaat ggcgacaaaa catgatttga ttttagaata
     6361 tattgaaagt ttacctgttg gcaatcgaat ttctgtaaga agcatcgcaa aagaattgaa
     6421 tgtcagtgaa ggaacagcgt accgtgcaat caaagatgca gaaaatgtcg gactagtttc
     6481 aacaattcaa cgagtaggga ccatccgtat cgaacgcaaa ttaaaaaaac atattgaacg
     6541 tttgacattt ggcgaggtcg tcaggatcat tgaaggggac gttttaggcg gggcggcagg
     6601 attagacaag gtcttgaata aattcgtcat cggcgcgatg actaaacatg ccatggaacg
     6661 ctatattacg ccaggatcac taatgatcgt cggcaaccgg gcggaagtcc aaaaattagc
     6721 attggaagat ggcgccgcag tattgatcac aggaggattc aatacgactg ctgagattgc
     6781 aaagctagct gatgatcttg aaatgccgat cttacgcacc tcttatgata catttacagt
     6841 cgcaaccatg atcaaccgag cgttaagcga ccaattgatc aaaaaagata tcatgcttgt
     6901 cagtgatatc tatatgccag ctgaaaagac tcattatttg cagcagacag atacgatttc
     6961 tgattatcag cgtttgtcag aagaaacgca gcattcgcgt tttccagtcg tcaaccgcca
     7021 tcatcgtttg atggggattg ttacggcaaa agatgtttta gggaaatcgc caaaccagat
     7081 catcgatcgg gtgatgacga aagaaccaat cagtgtaaag aaaacaatga gtattgcctc
     7141 tgttagccat caaatgatct gggatgggct agaagtcatg ccggtcgttt ccgatgactt
     7201 gacattggaa ggcttgatta cccggcaaga tgtaatgaaa gcgatgcagc ttgtccagcg
     7261 acaaccgcag attgcagata cgatttcgga tcagatatct ggaaatatcc atacgattga
     7321 tactgaccgt gaaggaaatc gtttggaaaa ccctaagttc aaattcgtag tagcaccaca
     7381 aatggtcaat ggcgttggaa ccatttcttt tggcgtactt agcgaaatca tttctgatgt
     7441 cgcacaaaaa acaatggtga tgaaccaaaa acgaaatatc ttgattgaac aagtgaacct
     7501 acattatttg cggctgatcc aattggaaag cgaattagac attcgtccac gtgtattgga
     7561 aatcggcaga cgttccgcta aactggatat cgaagtgttt attgaaaaca ccatcgtttc
     7621 caaagcaatc gttgtttgtc aagtaatgga acgttcttag aaagcaggag tgaaatgaca
     7681 gtacagcaag aaatagtaga tacaataaaa aaatacgata aaatcattat ccacaggcat
     7741 ttgcgccctg atcctgatgc attaggatca caagtaggat tagccgaact attacgggaa
     7801 agtttcccag aaaaagaaat acgtcaagta ggtgaaacga ttgaagggct tcgcttttta
     7861 gcagaaatgc aagaagttga agatgtcttc taccaaggag cgctagtcat cgtgactgat
     7921 acagctaatt cacccagaat cagtgatcaa agatatcagt tggcagaaaa actgatcaaa
     7981 atcgaccatc atcccaatga tgacccttat ggagatcttg tgtgggtaaa tacaaaagca
     8041 agtagctgta gtgagatgat tgcagaattt gctttgatgt ttcctgaatc tttaaagatg
     8101 aacgttaagg ctgcacggtt actttatgca ggaatcgtcg gagatacagg gcgctttttg
     8161 tatccctcca cgacgtcccg tacattagag attgcttcga tattgagaaa ttatccattt
     8221 gatgcaagtg ctttgaacag agagattgaa caaatgccga tgaaagtcgc taaactttcc
     8281 ggttatcttt atcaaaatat ccaggtggat gaaaatggtg caggaagaat aatccttccg
     8341 caagaaattc ttgataaata tggaatcgat gattcagaga cagcttcgat cgtttcactt
     8401 cctggagtga ttgacgaagt gctggcttgg gggatttttg ttcagcagcc ttcagggtat
     8461 taccgcgtac gtttacgttc taaggggccg atcatcaatg aattggctaa acgccatcat
     8521 ggaggaggcc atccattagc aagtggtgcg aatgcaaaag atttagcaga agtagaggaa
     8581 atctataaag agatccaaga tatatgccaa tcgtataaga gcagaaaaac agaatgatac
     8641 ttcgttcgaa aacgtgcctt ttgtagtaaa aatcacaaat gtatcttttc aagatcttct
     8701 ttttccgtta caatagtgct cactaaagat tttaaaggag aaagaagatg acattaccaa
     8761 attgcccaga atgtggctca gagtacacat atgaagatcg aggcttgttg atttgcccag
     8821 aatgcgggaa cgaatggaac aaagaagaac aagaaactgt catagaagac ggattagtgg
     8881 tattagatgc aaatggaaac cgtctgttag agggcgatag cgtgacagtg attaaagact
     8941 tgaaagtaaa aggtgcgtca ggtgccatta aacaaggaac aaaagtcaag aacatccgtt
     9001 tagtagaagg cgatcataat atcgattgca aggtagaagg atttggaccg atgaaactga
     9061 aatcggaatt tgtgaaaaag aattaaagaa tattcaaggt cttttcacat tcttttccta
     9121 ctactaatga taaaataaag taaacgaaaa ggagtgaaac gaaaatgtat ggttatggaa
     9181 tgtatggttt tttagatccg acatttcttt tggtcattct tggattagtt atttccggaa
     9241 ttgcgtcagc gtacgtcaat agtactttcc gaaaatacga tcaagtgaga agcaaaaaca
     9301 atgtgactgg tacacaagca gcacaatata tattacaaag tcaacagata aataatgtcg
     9361 gtgttcaaca aattgccgga gatctcacag ataactacaa ttcaggtaat aagatgttga
     9421 gtttgtctca agcaactgca cagtctactt cagttgctgc gataggtgta gcagctcatg
     9481 aatgcggaca tgcggtacaa gatgcttcgg gttatgtccc attgaagatt cgtgcagcac
     9541 ttgttccagc agctaacttt ggttcgatga tttcgttccc cttgattatg gtaggtgtat
     9601 tgcttagctg gaactctacg ttaatcaata tcgggatttt cgctttttct ttagcattac
     9661 ttttccaatt ggtgacatta ccagtcgaat ttaacgcgtc tcggcgagca atccaaattt
     9721 tgagtgaagg cggactactg acggaagaag aagtaccgat ggcaagacac gtattatttg
     9781 cagcagcact gacttatgtt gcagcagcgc tttcgacatt cctgcagctg ttgcgcttga
     9841 tcttattgtt cggcggcaac cgaagagatt aaaataaaga agttgtgaaa tcagcgcttt
     9901 gatctgagct aataccgaga gttagctgat tgaataccat ttatttggaa taagaggatg
     9961 tgacaagaat tttgtcacat cctctttgtt ttgttctcat aacctttttt catatacagt
    10021 tcatgaaccg cttttattaa cttgccaaat aacactgtat tgtgcgttgt atccagatag
    10081 aaagtctccg tttcatctga aattttctca tgctgatctg taatgatcaa atcagcatgt
    10141 tctgaatatg cggtaatttt aacagcatct ttgcgaaata actgctgcaa atggctttga
    10201 agatgataat ttcctgtaaa ctgtttggtt atctgcaaat ggatgagtaa ctgctctttc
    10261 gtttctgttt gtagtaagtg ttggatcaat tgactaaggt attgactgat ttggtttctt
    10321 tccccatttt ttgaaaaaat tgtatcgatt ttttctctta atttcttttc ctgtataaaa
    10381 gaactagaat gattggacgt ggcttctgga aagcaaagtg tagaaaaact actgctggat
    10441 tcacccaaca gttcgaaaaa aacaactgcc aacacaagaa aataaaaata aattggtatt
    10501 ttattttcta aatggttgag aggaaactgt tgagttaagt aagtcatcaa ttgaccgact
    10561 tgtcgacaaa taaggttttt gcttgtggaa
//
LOCUS       DAIGQM010000081        10123 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.084, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000081 DAIGQM010000000
VERSION     DAIGQM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.084"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(561..1601)
                     /locus_tag="NOA48_002381"
     CDS             complement(561..1601)
                     /locus_tag="NOA48_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0790613.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="NOA48_002382"
     CDS             complement(1950..2276)
                     /locus_tag="NOA48_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790614.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3066)
                     /locus_tag="NOA48_002383"
     CDS             complement(2263..3066)
                     /locus_tag="NOA48_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0790615.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="NOA48_002384"
     CDS             complement(3419..3709)
                     /locus_tag="NOA48_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0790616.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="NOA48_002385"
     CDS             complement(3845..4024)
                     /locus_tag="NOA48_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790617.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="NOA48_002386"
     CDS             complement(4021..4371)
                     /locus_tag="NOA48_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790618.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..5689)
                     /locus_tag="NOA48_002387"
     CDS             complement(4364..5689)
                     /locus_tag="NOA48_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0790619.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6139..6753
                     /locus_tag="NOA48_002388"
     CDS             6139..6753
                     /locus_tag="NOA48_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0790620.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6918..7742)
                     /locus_tag="NOA48_002389"
     CDS             complement(6918..7742)
                     /locus_tag="NOA48_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790621.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(8379..8636)
                     /locus_tag="NOA48_002390"
     CDS             complement(8379..8636)
                     /locus_tag="NOA48_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0790622.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8629..8898)
                     /locus_tag="NOA48_002391"
     CDS             complement(8629..8898)
                     /locus_tag="NOA48_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0790623.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9029..9208)
                     /locus_tag="NOA48_002392"
     CDS             complement(9029..9208)
                     /locus_tag="NOA48_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790624.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9589..>10123)
                     /locus_tag="NOA48_002393"
     CDS             complement(9589..>10123)
                     /locus_tag="NOA48_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790625.1"
                     /translation="QTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
BASE COUNT         3098 a         1842 c         1454 g         3729 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgtcaattt gcttttgtgg atcactaaat aaatccagct
     4561 gaagcgaatc ggtgtacaca agcttgctat aggttattcc aacgtgcctt acttcttgtc
     4621 cttcataata cttatcaaac aagaaaagac aataattctg caattccttt gtattatctg
     4681 tgataggtat tttcatctgg tgtgaaaatc ctggtctcgt ttctaagatc gacgtaccaa
     4741 tgtttaaatg aacacatcct gttttacaat tatgctgcct gatacgaatg gctacttgtt
     4801 ccgccatttc ttttaccacc agctcgattt catttcttct agtataatct cgtggtaaca
     4861 cttgtgaatt accataagat ttttcctttg tcggttctgg cgggattgct atatctgttc
     4921 gatcgattcc gttagcatgg aagtacagct gtaatccaat cacacctaat ctattcttaa
     4981 tcgtataagg attccagtta gcaaggtctc taatgctcaa aattcccatt tggttgagcc
     5041 tttttttcat tcgcgaacca attccccaaa agtccgtcat ttcgggaata ttccatactt
     5101 tctcaggaac gttttcgtac gtccattccg caataaatcc ttcattatgc tttgcttcat
     5161 tgtctaaggc taatttagcc aaaaggggat tatcgccgac gcctaccgta gcaatcaaac
     5221 ctaactcttc tttaatacgt tcttggatca tttgagcgag cttcttcctt cgctgacttc
     5281 gtgtttcttc agtcgtaaaa agattcagtg attttgtcac ttttaaaatc gattcatcga
     5341 tcgagtaaat cagtagatct tcatcagcca catatcttct gaaaatatta tttacctgca
     5401 tatttcgctt gatatatagg ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg
     5461 gttgtggtaa gtcacgtggt ctactcacat ttgtaatacc ataccgcttt tttgcttcag
     5521 gagaagaagc taatatcaat cctgaaccag tattatcaga tcgactcata acaacaagtt
     5581 ctgttgttaa tggatctaaa tttctttcta tacattcgac acttgcgtaa aagcttttca
     5641 tatcgattaa aaagtaatca tttactggct cttttgaata atccatcata aataacactc
     5701 cattcttcca cattatacaa acatatgttc gatgttgtaa agaagaaata gctaaataca
     5761 taaaaaaaga agcataggta tgctatcacc ctgcttcttc ttttgatttg tatgatcaat
     5821 ttgttctatc actttactaa ttaatttgaa aatctaataa aaactctcac tctaaaagag
     5881 tgagagactg caaattagag tacggacttt tttggagttc cgttctttaa tattaacaaa
     5941 tgaataaaat ccttacaaca tttgagaata agttatcagt agacacttac aaaaaattct
     6001 catactattt cctccatcat tagtttttgt ctatataagg tttaccctaa atagacactg
     6061 gtataacatt gaaaaatatg gcttcctcgt gtatgattag ggtgtatttt aaatagttgc
     6121 agaaagtagg taaaagtttt gagagttgca tacatacgtg tctcatcgat cgatcaaaat
     6181 gaacaacgcc agattgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa
     6241 caatctggcg caacgattac tcatcgacct gttttccaag aagcattaga ttacgtccga
     6301 gatcaagata tttttattgt ggaagctatt gatcgacttg gaagaaatta tgacgagatc
     6361 atcgcttcag tcaattactt gaagaagaaa aatgtgaagc tgatcattac tagtttaccg
     6421 atcatggctg aagcaattgg caatcctctc ctggataaat tcattaagga tctgatcatc
     6481 caaattttgg ccatgatcgc tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa
     6541 ggaattaaga tcgcaaaagc aaacggcgtc tacaaagggc ggcccaaatt atacagtgca
     6601 gacgcaaaag atccccaacg tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat
     6661 ggtgttgcga ttgctaagat tgctaaagac tacaatgtta cgagacaaac cgtgtataga
     6721 ataaaaaaag acagcatggt caatgacaaa tagttgatca tgctgctttt attatcttct
     6781 catctttaat ttcctacata taattactat ctataaaatt aagtcttact cagaacagat
     6841 aaagcataaa attccaacaa accatttttt acttaactaa ataaagagtc tgttaatata
     6901 atcttcactt atttacgtta atcccctact gtatttgttg gttccttatc tatattttct
     6961 acaaaatcct tattatcttg tgatttagct tcgtataatt ctttgtatgt cgacacattg
     7021 gttatactaa ttcctatagc tagttcttga gactctactt ttctctctag ctcctttgac
     7081 aaagtgattt gagatttatt tggttccgtt ggagtcaatt ctatagattc ttcataaaaa
     7141 tctctataca taaagctatc attaatttta taaaaaaaat taaatgtttt tagcactgcc
     7201 atataacatt caaaacattc ttctatagtt ggtttacttc cttgaggaga atgaaccaat
     7261 ttattacgtt tttctatgaa atttttaatt tcctttctta tttctttcgg aaactcaata
     7321 ttaaagtacc ctttaaacat gctccctaat aatttgtcta cagggggaga ttgtaaattc
     7381 tcaaatatta gagttaaatc aggtttctct tgttgataaa attcctttac ccctatttca
     7441 caggctgtaa ttatcgaaat aaacctatct ctagtatttg atatattttt acttctttta
     7501 aggagtataa gagaaaaggg gatactttcg tgtccatgca tgtaattaac taattgttga
     7561 gcttcagaag ttatatctct aattatatag ttaacggaat taggaagtgt ctttaactct
     7621 aatgaaattt ctatccaatt actatcttct aatctgtata tgctcgaagt ataatttgat
     7681 tcgtcagcaa gcatcgctac atcccaaaca ctgatcataa aatcttttaa acgttcaatc
     7741 atttcagcaa tattgctaaa atcagctaat ttttctttag aataaaaaaa acatttatat
     7801 cagaatcaat aaattctatt tttttattac tatatcgtca tcattatctt gaccatttat
     7861 gtttattgtt ccctgagtgg ggagtacttc tttcaaattc aagttaaatt tatattccat
     7921 tacttctcct ccaatatata aaaattactt aactgtatcc aaatttaata tgtaaataaa
     7981 tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg ctaattaact
     8041 aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc tattcagtca
     8101 tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta ttataacata
     8161 tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc ctcaacttta
     8221 gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc attaataaca
     8281 atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata aggatcaaaa
     8341 acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc ttttgcagaa
     8401 taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc tgtaattctt
     8461 ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa tccagcaaag
     8521 ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct tttgtttcct
     8581 tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt aatcatcaga
     8641 ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt catctcctcg
     8701 acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt gcatagaatc
     8761 ataatctctt tttgataata caacaactgt atcttctaca tctttacttg ttacaataag
     8821 tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc ggaaatttga
     8881 ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca attgtacatt
     8941 atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa agtgctatca
     9001 cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc tcaaatcctg
     9061 ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat tcacttttgc
     9121 cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac gtaacgggta
     9181 accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga aataacccta
     9241 tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat acaaagcgcc
     9301 aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa tgcacagctg
     9361 cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga atgattttat
     9421 tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat ttcgcaccac
     9481 ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc cttagttact
     9541 aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt attgcctttt
     9601 tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt ggatttcttc
     9661 tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc agtcgtcgcc
     9721 tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag cgagttcata
     9781 atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag taaatacaag
     9841 gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt cttccattaa
     9901 ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt tcctgcaaat
     9961 cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat tcatgatgta
    10021 tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag gacgacgttt
    10081 atacacgtct aaacgattat ggctgactgt gaccttcgtt tga
//
LOCUS       DAIGQM010000082         9826 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.085, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000082 DAIGQM010000000
VERSION     DAIGQM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.085"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..658)
                     /locus_tag="NOA48_002394"
     CDS             complement(<1..658)
                     /locus_tag="NOA48_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0790626.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     K"
     gene            complement(663..1430)
                     /locus_tag="NOA48_002395"
     CDS             complement(663..1430)
                     /locus_tag="NOA48_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0790627.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1920..2345
                     /gene="lacA"
                     /locus_tag="NOA48_002396"
     CDS             1920..2345
                     /gene="lacA"
                     /locus_tag="NOA48_002396"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HCI0790628.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2362..2877
                     /gene="lacB"
                     /locus_tag="NOA48_002397"
     CDS             2362..2877
                     /gene="lacB"
                     /locus_tag="NOA48_002397"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HCI0790629.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2888..3820
                     /gene="lacC"
                     /locus_tag="NOA48_002398"
     CDS             2888..3820
                     /gene="lacC"
                     /locus_tag="NOA48_002398"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HCI0790630.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3823..4803
                     /gene="lacD"
                     /locus_tag="NOA48_002399"
     CDS             3823..4803
                     /gene="lacD"
                     /locus_tag="NOA48_002399"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0790631.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPAIKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4831..5148
                     /locus_tag="NOA48_002400"
     CDS             4831..5148
                     /locus_tag="NOA48_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0790632.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5148..6854
                     /locus_tag="NOA48_002401"
     CDS             5148..6854
                     /locus_tag="NOA48_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0790633.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7001..8407
                     /gene="lacG"
                     /locus_tag="NOA48_002402"
     CDS             7001..8407
                     /gene="lacG"
                     /locus_tag="NOA48_002402"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0790634.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8530..8703
                     /locus_tag="NOA48_002403"
     CDS             8530..8703
                     /locus_tag="NOA48_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HCI0790635.1"
                     /translation="MKLPPLLKCGKWYVLTGKEWICHSDLELSAFEWEFLQSLDVEIR
                     ETIHFEVNYLPFQ"
     gene            8724..9623
                     /locus_tag="NOA48_002404"
     CDS             8724..9623
                     /locus_tag="NOA48_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI0790636.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNCPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDKL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3094 a         1666 c         1976 g         3090 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagcagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttt cgtgtattta ggaaaagcaa catcagacca acatctgaaa cgtttgtaaa
      541 tgttatctat ttgttggata tcaatcgttg gaaaacattt ctcaacgcta cgtttaaagg
      601 ggagttgatg gtcataaaga gtgtcatcaa ggtcaaaaac aatattttta taagtcataa
      661 ttctagtccg cttttaaaat agtagtgtac tggctaaatt cctctaagtg ttgagggcta
      721 atctggttat ctgtaatgat ggtatcgagt tgatctagat tatagaagtt aaagaaatcg
      781 tatcgatcga atttagtact gtctactaat aagaattttt ctacagcatt gtttagggca
      841 agttgttgaa tcacaccttc cttgtcacta tatgtagcaa tagaattatg ggtaacagca
      901 tttgcactaa caaaagcttt ggcaaatcta attgctttta aatttgtcga agccattgaa
      961 cctacaaaag ctccagttat ttctctatat tcaccgccaa gaagcaataa atcaatggtt
     1021 tcgctatcat ttagaatcaa gaacacaggg agactatttg taatgacacg aattttataa
     1081 cctttacgac ctttcaattc taatgccagt tgttcaagtg tagttccggg tccaataaaa
     1141 atagtatcgc catctttgat taaagagcag gcttttttag caatgtcaat tttttctttt
     1201 gtatttagac ttttcttctc gatatgtgtc ttttcaagtg gctttttaga ggaaagcaat
     1261 tgtgcaccac catgagtacg tgttaaaagt ccatcagctt ctagagcatc aaggtctcta
     1321 cgggctgtca tatcggaaat atctagttca tctattattt cttttatggt tatggtccca
     1381 tcaatcttta acatatctaa aattttttct aatcgtcgtt ttttgttcat atgaagaccc
     1441 ttctttcata aagtaatttt tttccaaaga taattctctt ttaattgtat cataaaagac
     1501 aatattttca aggtaaaaca aacaatttca aacaaaaaca aatgttagat gatgaaataa
     1561 gaacagtgga ttgacgtata ttagcttagg tcagattttg tataagacga aaataaagta
     1621 ggacctctta atcagtaagt tatagaaagt aaaagacttt tgtaatactt gaatagatat
     1681 ttcacgtcca ttttgtgatg gattaaatga acaaaaatga acaataattt aacggtgtta
     1741 tctatttttt aaaaaaacaa ataaaaaaaa caaaaaataa acaaaaaaag tgttgctttt
     1801 tgtttgaatg cttgatatta tataaacaaa gaaatgatga aaacgttttt tcgaacattt
     1861 tgcaaaatgt tttctacttc tacgtagcat ttctttctaa aatttaggag gtggtcaaaa
     1921 tggctattgt tgttggtgca gatctcaaag gtacgagatt aaaagatgtt gtgaaaaatt
     1981 ttcttgtaga agaaggtttt gaggtaattg atgtgactaa ggacggacaa gattttgttg
     2041 atgttacctt ggcagttgcc tctgaagtaa ataaagatga gcaaaactta ggtattgtaa
     2101 ttgatgctta tggagctggt ccattcatgg tagcaactaa aattaaaggt atggttgcag
     2161 cagaagtttc agatgaacgc tcagcttata tgacacgtgg acataacaat tcacgaatga
     2221 ttacggttgg cgctgaaatc gtcggtgatg agcttgctaa aaacatcgct aaaggtttcg
     2281 tcaatggtaa atatgatggc ggacgtcatc aaatccgagt agatatgctt aacaaaatgt
     2341 gttaagaaaa ggagttaagg aatgagaatc gcaattggat gtgaccacat tgtcacagat
     2401 gaaaaaatgg cagtatcaga attcttgaaa tcaaaaggac atgaggtcct tgatttcggg
     2461 acatatgacc acgcacgtac tcactaccct atctatggta aaaaagtcgg tgaagcagta
     2521 gtaagtggtc aagcagactt gggagtatgt atctgtggta caggtgtcgg cattaacaat
     2581 gcagtcaata aagttccagg tgttcgctca gcgttggttc gtgatatgac atcagctata
     2641 tatgcaaaag aagagttaaa tgcgaatgtt atcggtttcg gtggaaagat tactggtggt
     2701 cttcttatga atgacatcat tgaagctttc attgaagctg agtacaaacc aacagaagaa
     2761 aataaaaaat tgattgcaaa aatcgaacac gttgaaacac ataatgcaca tcaagcagat
     2821 gaagatttct ttacagaatt ccttgaaaga tgggaccgtg gtgactacca cgattaaggt
     2881 ataacaaatg attctgacag tcacactaaa tccttcagta gacatctctt atcctctaga
     2941 aacattgaaa attgatacag tgaatagggt gaaagatgtt agtaagacag ctggtggaaa
     3001 aggcttaaat gttactagag tcttgtatga atctggtgat aaagttactg ctacaggttt
     3061 cttaggtggt aaaattggtg aatttattga aagcgaatta gaacaatctc ctgttagtcc
     3121 agctttttat aaaatctcag gaaacactag aaactgtatt gctatcttac acgagggtaa
     3181 ccaaacagaa attttggaac aaggaccaac aatttctcat gaagaagcag aaggctttct
     3241 tgaccactat agcaatctta ttaaacaatc agaagttgtg acaatttcag gaagtttacc
     3301 ttcaggactt cccaacgatt attatgaaaa acttatccaa cttgcttcgg atgaaggagt
     3361 agcagtcgtt ttggattgtt caggtgcacc tcttgaaaca gttctaaaat cgtcggctaa
     3421 acctactgcc atcaaaccta ataatgagga actttcacag ttgcttggaa aagaagtaac
     3481 aaaagatatt gaagaactca aagacgttct taaagagtca ctttttagtg gtatcgaatg
     3541 gatagtggtc tcattaggtc gaaacggtgc ctttgcaaaa catggtgatg ttttctataa
     3601 ggtagatatt cctgatatcc cagttgttaa tccagtcgga tcaggggact caacggtagc
     3661 tggtattgca tcagctttaa atagtaaaaa aagtgacgct gacttattaa aacatgcgat
     3721 gacattgggt atgttaaatg ctcaagaaac aatgacaggg catgtgaata tgactaatta
     3781 cgaaacacta aactcacaaa ttggagtaaa agaggtataa aaatggtact tacagaacag
     3841 aaacgcaaat ctttggaaaa aatttcagat aaaaacggtg ttatctcagc tttggcattt
     3901 gaccaacgtg gtgctttgaa acgtttgatg gcacagtatc aagatacaga accaactgta
     3961 gctcaaatgg aagaactaaa ggttttggtt gctgatgaac ttacaaaata cgcttcttca
     4021 atgttgcttg accctgaata tggacttcca gcaataaaag cattggataa agaagcaggt
     4081 cttcttcttg cctatgaaaa aacaggttat gatacatcaa gtacaaaacg tttgcctgac
     4141 tgcttggatg tttggtctgc aaaacgtatc aaagagcaag gcgctgatgc cgttaagttc
     4201 ttgctttact atgatgtaga cagctcagat gaacttaacc aacaaaaaca agcttatatt
     4261 gaacgtgttg gttctgaatg tgtcgctgaa gatattcctt tcttcttgga aatccttgct
     4321 tatgatgaag aaatctcaga tgcaggttct gttgaatatg caaaagtgaa acctcgcaaa
     4381 gtcattgaag cgatgaaagt tttctctgat ccacgcttta acattgatgt tcttaaagta
     4441 gaagtaccag ttaacgttaa atatgtcgaa ggttttgctg atggtgaagt ggtttacagt
     4501 aaagctgaag ctgctgactt ctttaaagca caagaagaag cgactaacct tccatacatc
     4561 tacctaagtg caggtgtatc tgctaaattg ttccaagaaa cattgcaatt tgctcacgac
     4621 tcaggtgcca agtttaatgg tgtgctttgt ggacgtgcta cttgggcagg atctgtagaa
     4681 ccttacatca aagaaggtga aaaagcagca cgtgaatggt tgcgtactac tggattcgaa
     4741 aatattgatg aacttaacaa agttcttgtt aaaacagcta gtccatggac tgataaagta
     4801 tagtaaaaac ataaaacgga ggatattgtt atgaacagag aagagatgac tctcttaggg
     4861 tttgaaattg ttgcttatgc tggagatgct cgctctaaac ttttagaagc gcttaaagcg
     4921 gctgaaaatg gtgatttcgc taaggcagat agtcttgtag tagaagcagg aagctgtatt
     4981 gcagaggctc acaattctca gacagctatg ttggctcgag aagcttctgg ggaggaactt
     5041 ccatacagcg ttaccatgat gcatggtcag gaccacttaa tgactactgt cttattaaaa
     5101 gatgtgattc atcacctcat cgaactttat aaaagaggag caaaataatg cataaactca
     5161 ttgaacttat tgagaaaggg aaaccgttct ttgagaaaat ctctcgaaac atctatcttc
     5221 gtgctattcg tgatggattt atcgctggta tgccagtcat ccttttctca tctatcttta
     5281 tccttattgc ctatgtccca aatgcttggg gattccactg gtcaaaagac attgagacct
     5341 tcttgatgac tccttatagc tattcgatgg gtatcctagc attctttgtt ggtggtacta
     5401 ccgctaaagc tttgacggac tcaatgaacc gtgacctacc tgcgaccaat cagattaact
     5461 tcttatctac gatgctagcg tctatggtag ggttcctttt gatggcagct gagcctgcaa
     5521 aagaaggagg cttcttgaca gccttcacgg gaacaaaagg tcttttgaca gcatttattg
     5581 cagcctttgt gacagttaat gtttacaagg tctgtgtgaa aaataatgtt actattcgta
     5641 tgcctgaaga ggttccacca aatatctctc aagtatttaa agacttgatt ccattcactg
     5701 tagcggttgt tctcctttat ggatttgaac tcattgttaa gggaactctt ggtgtaaccg
     5761 ttgcagaatc aatcggtacc cttcttgctc ctctcttctc agctgcagat ggttaccttg
     5821 gaattacact gatctttggt gcttatgcct tcttctggtt tgttggtatc cacggtcctt
     5881 caattgtcga accagcaatc gctgctatca cttatgccaa tatcgatgcc aacttgcatc
     5941 ttatccaagc tggacaacat gcagataaag ttatcacttc tggtactcaa atgtttattg
     6001 ttaccatggg tggaacagga gctacattga ttgttccatt cttgttcatg tggatttgta
     6061 aatcagaacg taaccgtgcc atcggacgtg cctcagttgt tccaacattc tttggggtta
     6121 atgagccaat cttatttggt gcaccaatcg tattgaatcc gattttcttt gtaccgttca
     6181 ttttcgctcc gattgtcaac gtttggatct ttaaattctt tgttgacaca ttgaacatga
     6241 actcattctc tgccaacctt ccatgggtta ctcctggtcc gttgggaatt gtactcggta
     6301 ctaacttcca agttctatca tttatcttag ccggactctt ggtagttgtt gatactatca
     6361 tttattaccc atttgttaag gtatacgatg aacaaattct tgaagaagaa cgttctggta
     6421 aaacaaacga tgctcttaaa gaaaaagtag ctgcaaactt caatactgct aaagcagatg
     6481 ccgttcttgg aaaagcaggc gttgctaaag aagatgtagc agcaaacaat aatatcacaa
     6541 aagaaactaa tgtccttgtt ctttgtgcag gtggaggtac aagtggcttg cttgccaatg
     6601 ccttgaacaa agcagcagca gaatacaatg ttccagtcaa agcggcagcg ggtagttatg
     6661 gtgctcaccg tgaaatgttg ccagagtttg acttggttat cttggctcca caggtcgctt
     6721 caaacttcga tgatatgaag gctgaaacag ataaattggg cattaaactt gcaaaaactg
     6781 aaggagctca atatatcaaa ttgacacgtg atggacaagg tgctcttgca tttgttcaac
     6841 aacagtttga ttaataaatt tgtaaaagtt atttgagacg agattattct ttcagttcct
     6901 tataatattg ttaaccatat cattgcattt catttcattt ccttggtttc cggaactcag
     6961 aatatcgtct caaatgcttt ttttgaaagg atttatagtt atgactaaaa cactccctaa
     7021 agattttatt tttggtggtg ctacagctgc ttatcaagca gaaggtgcga ctcacacgga
     7081 tggtaaaggc ccagttgcat gggataagta tcttgaagac aattattggt acacagcaga
     7141 gcctgcaagt gatttttacc ataaatatcc tgttgattta gaattagctg aaaaatatgg
     7201 cgttaatggt attcgtattt caattgcctg gtctcgtatt ttcccaactg gctatggcga
     7261 agtaaatgaa aaaggtgttg aattctacca taatcttttt gccgagtgcc acaaacgtca
     7321 tgttgagcca ttcgtgactt tgcaccactt tgacacacca gaagttcttc actcagatgg
     7381 agatttctta aaccgcgaaa atatagaaca ctttgtagat tatgccgctt tctgttttga
     7441 agagttccca gaagtaaact actggacaac tttcaatgaa attggcccaa ttggagatgg
     7501 tcaatacttg gttggtaaat tccctccagg cattcaatat gatcttgcca aagtcttcca
     7561 atcacaccac aatatgatgg tttctcatgc acgtgctgtg aaattgtata aagataaagg
     7621 ttataaaggc gaaattggtg tagtacatgc gttgccaacc aaataccctt atgatccaga
     7681 aaatccagca gatgttcgtg ccgctgagtt agaagatatc atccataaca aatttatctt
     7741 ggatgcaacc taccttggac actattcaga taaaacgatg gaaggggtca accacatcct
     7801 agctgaaaat ggtggagaac ttgatcttcg tgatgaagac ttccaagcac ttgaagcagc
     7861 taaagatttg aacgatttcc ttggtatcaa ctactacatg agtgattgga tgcaagcctt
     7921 tgatggtgag actgaaatca ttcacaatgg taagggtgaa aaaggaagtt ctaagtacca
     7981 gattaaaggt gttggtcgcc gaatcgcacc agattatgtg cctagaacgg attgggactg
     8041 gattatttat cctgaaggct tgtatgacca aatcatgcga gtgaaaaatg attatccaaa
     8101 ctacaagaag atttacatca ctgaaaacgg tcttggatac aaagatgagt ttgtagataa
     8161 taccgtttat gatgatggtc gtattgatta cgtgaagaaa cacttggaag ttttatcaga
     8221 cgcaattgcg gatggtgcaa atgttaaagg ttacttcatc tggtcactta tggatgtctt
     8281 ctcatggtca aacggatacg aaaaacgtta tggactattc tatgtagact ttgacacgca
     8341 agaacgctat cctaagaaat cagctcattg gtataagaaa gtagcagaaa ctcaagtgat
     8401 agagtaatat tacttgaaaa tgtaaaaaat tgttatccga tactttagaa aaagtacaac
     8461 acttatttag accaggcttt gaaaaggtat atattgttag tttcgaagat tgtcctatga
     8521 ttcctgagct tgaagctacc cccgttgcta aaatgtggta aatggtatgt tttaactgga
     8581 aaagagtgga tttgccattc tgatttagag ttatcagcat ttgaatggga atttttacaa
     8641 tcactcgatg tagaaatacg tgagactatt cacttcgagg taaattattt gcctttccaa
     8701 taataaaaag aaaggaatta gttgtgacta tcgaattaaa aaacgagtat cttactgttc
     8761 agtttaaaac acttggtggt caactgactt cgattaaaga caaggatggg atagagtatc
     8821 tctggcaagc tgatccaaat tattggaatg gacaggcgcc tattctattt cctatctgtg
     8881 gtagtttacg aaatgattgg gctatttata gacctcaaga aagacctttt tttacaggtc
     8941 ttattcgtag acatggtttt gttcgaaaag aagaatttat tctggaagaa gtcaatgata
     9001 atagcgtgac ctttagtatt aaaccaaatg ctgagatgct tgataattac ctatatcagt
     9061 ttgaactgag agttgtttat accttgaatg gtaaatcaat tagaaccgaa tttcaggtaa
     9121 cgaacttgga aatggaaaaa acaatgcctt actttattgg agcccatcca gcattcaatt
     9181 gtcctttagt agaaggtgaa aactatgagg attattatat tgaatttagt gaggttgagt
     9241 cttgctcgat accaaagagt tttcctgaga caggattatt agatttgcaa gatcggacac
     9301 cttttttgga aaatcaaaag attctcgatt tggactactc acttttttcc catgatgcca
     9361 ttacacttga caagctcaag tctcgtagcg taacgcttcg gtcaaggaag tctggtaaag
     9421 gtcttcgagt agattttgat gattttccga acttgattct gtggtctaca actaataaaa
     9481 gtccattcat tgctttggaa ccttggagtg gtctctccac ttcacttgaa gaaggtaatt
     9541 tcttagaaga taaaagacag gtaacgaaaa tttcacctca agaaacttct agaaaaatct
     9601 atgatattac tatccttaat taaaatttgt tattatttga gtcttcaata agaattgaat
     9661 actcttacct tgtgatgata gattggtctt ctccgtgcca gtcttacatc gcaaggtttt
     9721 taagtttttt gtgggtctat gtcaactgta gtgggtgacg aaaagctaac atctaaagac
     9781 agtctggtag taaaaaaata agattattta ctacttcttg atttaa
//
LOCUS       DAIGQM010000083         9607 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.086, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000083 DAIGQM010000000
VERSION     DAIGQM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.086"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(489..1103)
                     /locus_tag="NOA48_002405"
     CDS             complement(489..1103)
                     /locus_tag="NOA48_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0790637.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1709..2086)
                     /locus_tag="NOA48_002406"
     CDS             complement(1709..2086)
                     /locus_tag="NOA48_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790638.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2386..3267)
                     /gene="galU"
                     /locus_tag="NOA48_002407"
     CDS             complement(2386..3267)
                     /gene="galU"
                     /locus_tag="NOA48_002407"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0790639.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3310..4329)
                     /locus_tag="NOA48_002408"
     CDS             complement(3310..4329)
                     /locus_tag="NOA48_002408"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0790640.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4962..5966)
                     /locus_tag="NOA48_002409"
     CDS             complement(4962..5966)
                     /locus_tag="NOA48_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0790641.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5979..7028)
                     /locus_tag="NOA48_002410"
     CDS             complement(5979..7028)
                     /locus_tag="NOA48_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0790642.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(7045..7866)
                     /locus_tag="NOA48_002411"
     CDS             complement(7045..7866)
                     /locus_tag="NOA48_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0790643.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7853..8632)
                     /locus_tag="NOA48_002412"
     CDS             complement(7853..8632)
                     /locus_tag="NOA48_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790644.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8649..9119)
                     /locus_tag="NOA48_002413"
     CDS             complement(8649..9119)
                     /locus_tag="NOA48_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0790645.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9131..9550)
                     /locus_tag="NOA48_002414"
     CDS             complement(9131..9550)
                     /locus_tag="NOA48_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCI0790646.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
BASE COUNT         2839 a         2057 c         1526 g         3185 t
ORIGIN      
        1 gcaaaaaaaa taataaacac ttataaatat ccattatcta tccttcaatt tttgtgtatt
       61 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
      121 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
      181 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
      241 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
      301 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
      361 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
      421 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
      481 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
      541 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
      601 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
      661 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
      721 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
      781 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
      841 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
      901 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
      961 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
     1021 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
     1081 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
     1141 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
     1201 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
     1261 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
     1321 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
     1381 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
     1441 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
     1501 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa cataaaaaaa
     1561 ggaatggctt atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga
     1621 aaaaagcttt tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt
     1681 atcttttttt gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt
     1741 cgagagaatc tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact
     1801 ttcttttcat atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata
     1861 cgcaagcttc ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg
     1921 ctgcatacca gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa
     1981 atagactaat aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact
     2041 tgagtatatc aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc
     2101 tttttttata attaaaaaat tcgccttttt attctactat gaatcttctg gcttggcttt
     2161 catttctctt atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca
     2221 taatattttc tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa
     2281 ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt
     2341 taataacaaa tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct
     2401 tagcttttta ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg
     2461 aagtccatat tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt
     2521 tcctttaaac tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt
     2581 tagctgtatc tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg
     2641 agtcagtaga taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt
     2701 ttctacaaac ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat
     2761 tccgtattta gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt
     2821 ttcttcataa tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc
     2881 ccccagcatg acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc
     2941 ccccagtcct cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc
     3001 aactaaagcg agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt
     3061 tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc
     3121 gattcccgaa tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg
     3181 aagcatttct tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc
     3241 aggaatgact gcttttttga ccttcacttg ctgttcctcc taaacgacga ttaactattg
     3301 atcatctatt taacgaagag aaaattcatt ctccattttt ccgtcacgta acatgatttc
     3361 ttttgctgct tttttgatat cttctccatt atacaaaaca ttatagattg tttgagtaat
     3421 tggcatctca acacctagct gttgagctag ctctactgct gcttttgtcg ttgccacacc
     3481 ctcaacgacc attcccatgt tttctagaac ttcttccagc ttatgtccct gtcctaacaa
     3541 gttaccggca cgccaattgc gagaatgaac acttgtacaa gtaacgatca agtcccccac
     3601 accactcaaa ccgataaatg tcagaggatt ggcacccatc gcgacaccaa gacggctgat
     3661 ttctgccaat cctcgagtca tgattgctgc ttttgcatca tctccgaatc ctaatccatg
     3721 gatagcgccg gcaccaattg caatgatatt tttcagtgct gcaccagttt ctacgccaat
     3781 cacatcatta tttgtataaa tcctgaaata atcattcatg aacagttttt gtacataggc
     3841 tgctgctttt tgatcaatac ttgcagctgt aattgttgtg atatcatgta ctgccacttc
     3901 ctcagcatgg ctaggaccag ataatacaac aattgcctgt cttttttctt ctggaatttc
     3961 ttcagccaaa acttctgaga ttcgtttatg cgtatcttgt tctagtcctt tacttgcatg
     4021 tataatgatt ggcttagtat tcattttacc aataagttcc tgtgcgactg aacgaatcgc
     4081 ttttgttgga acaacaaata aaatagcatc tgcgttatcc actgcttctg ccaattcttt
     4141 atatccgata atcgattctg ggatcgtcaa atcaggtaaa aaatgctgat ttgtatgata
     4201 cttattgatt tcatcaatct gttcaggtac atttccccaa atacggacat catgcccgtt
     4261 ttctgccaat gtttgtgcta aagcagtgcc ccaagatcca ggaccaagaa ctgcgatttt
     4321 ttgtttcatg gatattcctc caaataaata attgataatt tccattatag tatacatttc
     4381 ttaaagttgg gactaatttc cattgttttt aagtgtttgt ttacttcttt tatcgttttt
     4441 acttgaaata atcaatgata tgttacaata gtctacattt tatttttaca ctcgttatgc
     4501 tttgcttgtt cctaagagga agcagttttg acaatgttac taccagcatt actattagga
     4561 ggttaggaaa cttctcctag tgagtattga tttaaaatac ataagagaca gattgaacat
     4621 ttctaaatct gtcaggtcct gcaacggaca gattgtctct gttgacggtt gacataggaa
     4681 cttttgtttt agtcaacatt ctggatacaa aacgctatgt aaactggcgc aactcgttgt
     4741 acttggactt ttactacgga tccatgcaac aactaaatag tactattgca taacaaaaaa
     4801 tggttggcac ccacatgtcc cattaaacag attataagtt gaactgtaga taatgcaaaa
     4861 aatgtgtttt ataacgtaat tgatgccaat attttaaaaa aataaaggga gcagttatcg
     4921 ctgctctctt tattttttat attcttttta tccagtctat cctaataatc aaactgacga
     4981 tagtagcggc gtatctctaa tggatggcag ttcaactgct ccacatgagc atcgatgcgt
     5041 tgtgtcacta catgcatcaa taagaaagac aaaacacgtc cgcgatattt ttcactgata
     5101 ccttctactg gatagtcttt tgtgtctatc aatgtataat tgctgcaaat ttttggcaaa
     5161 agtttagcca cacgttcaga taacactctc tgttcatctt cgcctaaaaa taatgtgact
     5221 ggggttgttt cttctacgat ctctaacgtc ccgtgaagaa actcggcagc atggatagat
     5281 ttcgatggaa gccagctttg ttcttcccag taacacatgg catatgaata aacagctccc
     5341 cattgattcc ctgctccaat aaaataatgc atactatcac gtcgatgttt ttctgcaaat
     5401 gataagccaa atgcatctgc ttttttctct gcttccacta accctgttgg taaataacgt
     5461 tcgagctgtt catagtattc tgaataagct tcgaattctc cattcaaata catcaatcga
     5521 tctgctgcca taaaaaattt gatttgttct gttccaggag ctggataagt gaccacaaaa
     5581 tcgcatagct gagacaactt actgttcgct ttatcgataa atccaatcag tgtcgctcct
     5641 actttcttga tttgttctac tgctttcact acttcttgag ttgtaccggt aacagaggac
     5701 aaaataacga tagaatcttt tgttaatctt ttgtttccag tagtgtaata ttctgcagca
     5761 tgctgtacaa agacaggcaa gttgcttttc ccattcatat aagtgacagc ttgcatcgag
     5821 gaagcatacg ttccaccgat tcctagataa tagacagcgt caaatttttc cgcataaagt
     5881 ttatcgatga tttcttctac ttgcggacgt aaagctagtg cgccttttat tgctttgatt
     5941 tgttcttctt cattgaattt cagcatgatt tccacctctt ataatttact tttcaagact
     6001 gtatcaaagt cttcaaaaat ctttttgttc aagtcaatac ctttagctac tgcggtttta
     6061 taagcgaata gttgaaacgg aacgacaagc gctaatacag acagatattc atcacattct
     6121 attgctaatc caagtgtttt ctcgtttctt gctttttttg tggtaatggt gagagtctct
     6181 ccaacgtacc gactcatata tctttgcaac ttttgcgaac gttccttatt tacactttcc
     6241 ccttcaataa agaatagcaa atgcgaagca tctgcctcca ggtatgggcc gtgcatataa
     6301 gcttctaact caaatccttg tgacggaacg cggattgttt cagtcaattt cgtctctgct
     6361 tctttagctg ttccccagtt tggaccatat ccaatggtga cgaaacgctg tgctaaacga
     6421 aataaacttt gatatccatc aaaaaattct tccgtttttt gaataatcgc tggtaaatgg
     6481 ttgattattt tgcgcaactg ttgcatgtag tcttgttcta tttttttgct gattttattt
     6541 ttacttattc caattcctat ccctaagagt agtaactgta aaacagtcgc agaatagcct
     6601 tttgtaacga agcctactga ttctaccccg gcacctaaat caataatttg tgcagcttct
     6661 aaagcaagtg gactttgcac gtcatttgtg atagcaacaa caggtaaccc ttgtttttgt
     6721 atcattttta ctgcttcaac agtagaagca cttttcccgc tttgtgacac agcaatcaca
     6781 gtatcgattg aaggagaaag ttttccataa ttgaaaaaat aaaaaggttc ttgaatatcg
     6841 acagtaagat caccataaga ttccaatgct ggcttcgctg ctaaacaagc gttataagat
     6901 gaacccgttg ctaagatcag taaattcact gtttttttca tatgttctct tgtcgaaaaa
     6961 tcattctttt tcaagatcgt acttagtact tccttttctt catagatata atcttgcatc
     7021 gtaaacattt tctctgctcc ttttttaaaa aatccctatc cacgaaccaa aaattccaaa
     7081 gaaagctagt ccgatcaaga tcgttaatgg tttcacttct ttcttcaata gataaaacac
     7141 tatgccaaat gctccaagac ataagatatt tggaacgata tcatcaaaaa tactttgaac
     7201 agtcacagca ttttctcctg aaccgatttt taaaggaata ttgatggtga tcatcgtggc
     7261 agtcattgct ccaacgacca tcagtccaat aatagacgcg cctaatgtca aactttccat
     7321 cataccgttt gcctggatct ttttcaaaaa acccgttcct aagcgatatc cccaacctgt
     7381 tgctagatag cgaaacagaa tgtgcggaat attgaaaatc aaaatgaaca agatagggcc
     7441 taaaatattt ccttgcatgg ctaaagaggt acccacacct gtggcaatca atcgcaaagt
     7501 tccccaaaag aaagaatctc ctaaccctgc aagaggtccc atcaaagatg ttttgatact
     7561 atcgatcgca gtcacatcaa attcaggatc atccttattt tcttcctcca ttgcagccgt
     7621 gattcctaaa atcagtgtaa cgatatgtgg ggtcgtgtta aaaaactcta gatgccgttt
     7681 caaagctgct gccatttctt ctttcgactg atataacttt ttcaaaatcg gaatcattgc
     7741 ataaacataa gccatattca tctgacgttc ataattccaa gaaaactcca tttgaaaaga
     7801 acgccaaaat acgtgattta gctctttttt cgttattttg ctgtttttga tctcagaatt
     7861 cttcatcttc ttctacctcc cctgcagttg tttgaagtgg tagttgacgg acattcataa
     7921 tattgactac cacaactgct aaaatcgcac caaaaatagc tactccggtc acaggaatct
     7981 ctaagtaaga agctatagca aaacctaaga aaaaatatgg tgcaacttgt ttgttgatca
     8041 gcaaacgagc aagcatcgca aaaccaagag ctggaatcaa ccctgtagct actgacaacc
     8101 ccttttgaac gaagtcagga atcatattta atagatttcc gatcgtattg cttcccacca
     8161 tataagaaac cattaccaca acaccaagca tcaaggaaag accgataccg gcaagcaagt
     8221 gcatatgctc gactccttta taatttcctt cttctgcata attgtctgct ttatggttca
     8281 taattggaat caaaagccct aagtaaatat ttttcaatat caatgtcaac gtagcaatcg
     8341 gcaaacctag taaaagcgcg gtttctgtac cggctccagc tgtaatagca aaagccgtcc
     8401 ctaaaatccc accggtcaca acatcaggtg gaatcgaagc acctactgag aacgatccga
     8461 taaatgctaa ctctaaagtt gcgcccataa tgatcccagt ttttacatca cctaacacga
     8521 ttcctgtaaa cagccccgtc acaatcggac gagaaagcaa cgatgtccct agtgcatatt
     8581 ctgattgtgc gacaaatgca acaattccta ataagactgc ttgtacaatc attgaggttc
     8641 ttcctttctt acaaaacttc tcttacatcc acttttttat ctgctggtac ttgacggatt
     8701 tctacttcta tttgtttgtc aattaatcgt ttcaagcgtt cctcctcttc tggtaaaata
     8761 tttaccgctt ttccgatgct gcgagtacca ggttttgcct tgatccctcc taagttgatg
     8821 gttttgattt ctggatacgc ttctgccagc ttatatgcat cctcgatcga ttccactacg
     8881 atgaataact tatatttatc tgtcaccccg cttttcaacg cggcaatcga gtcatcaatt
     8941 gatttgatca ctagtttgac tccttgtggc ttggctaatt tgatcgttgt ctttcgtatc
     9001 tcattcgtag gtacatcatc attagcaatc aaaatacagt ctgcgcctat tgtttgtgtc
     9061 catgaaaaag ctacttgtcc gtgtaataac cgatggtcga ctcttgtcaa tacaatcatt
     9121 tttcttcctc ctaaaattcg tcttcttcta ttttctgatt gagccgctcg ttacaaaact
     9181 ggatcatttt ttttgaatca gttagcacct gctggatcaa aacagttgtc tctacttcag
     9241 cgtccaaccg agatactagc tcaatcaata gtggcaaatt caatccggca acgagataga
     9301 catgatcccg attgatatat tgtaagaatt cgttgttgac acttccgcca aaaagatccg
     9361 tcagaacaat gatttcttta tctttgtacc tcataaaaag ctgccttact gtttccgcta
     9421 aatcaaaatt ctcatcagta tagcaatcga atacagtaat agaatgattt ttcccataga
     9481 tcagctctaa tgaatctaat atccctgaag caaattttcc atgggaagct aagataattt
     9541 ctctatccac tttttcatct cctcttttca cttacacata ctaaaaaagc aagttgcatg
     9601 ccaaaat
//
LOCUS       DAIGQM010000084         8593 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.087, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000084 DAIGQM010000000
VERSION     DAIGQM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.087"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(52..1518)
                     /locus_tag="NOA48_002415"
     CDS             complement(52..1518)
                     /locus_tag="NOA48_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCI0790647.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1905..2501
                     /locus_tag="NOA48_002416"
     CDS             1905..2501
                     /locus_tag="NOA48_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0790648.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2559..3041)
                     /locus_tag="NOA48_002417"
     CDS             complement(2559..3041)
                     /locus_tag="NOA48_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790649.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3147..3344)
                     /locus_tag="NOA48_002418"
     CDS             complement(3147..3344)
                     /locus_tag="NOA48_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790650.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3639..4397
                     /locus_tag="NOA48_002419"
     CDS             3639..4397
                     /locus_tag="NOA48_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI0790651.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4457..4885
                     /locus_tag="NOA48_002420"
     CDS             4457..4885
                     /locus_tag="NOA48_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790652.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4931..5003
                     /locus_tag="NOA48_002421"
     tRNA            4931..5003
                     /locus_tag="NOA48_002421"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4964..4966,aa:Gln,seq:ctg)
     gene            complement(5153..5524)
                     /locus_tag="NOA48_002422"
     CDS             complement(5153..5524)
                     /locus_tag="NOA48_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0790653.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5739..5924
                     /locus_tag="NOA48_002423"
     CDS             5739..5924
                     /locus_tag="NOA48_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790654.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6007..6195)
                     /locus_tag="NOA48_002424"
     CDS             complement(6007..6195)
                     /locus_tag="NOA48_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790655.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6219..6482)
                     /locus_tag="NOA48_002425"
     CDS             complement(6219..6482)
                     /locus_tag="NOA48_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790656.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6640..6897
                     /locus_tag="NOA48_002426"
     CDS             6640..6897
                     /locus_tag="NOA48_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCI0790657.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6968..7159)
                     /locus_tag="NOA48_002427"
     CDS             complement(6968..7159)
                     /locus_tag="NOA48_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790658.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7300..7620)
                     /locus_tag="NOA48_002428"
     CDS             complement(7300..7620)
                     /locus_tag="NOA48_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790659.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7643..8077)
                     /locus_tag="NOA48_002429"
     CDS             complement(7643..8077)
                     /locus_tag="NOA48_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0790660.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8412..>8593
                     /locus_tag="NOA48_002430"
     CDS             8412..>8593
                     /locus_tag="NOA48_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0790661.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2724 a         1695 c         1362 g         2812 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta
     1681 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
     1741 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
     1801 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
     1861 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
     1921 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
     1981 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
     2041 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
     2101 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
     2161 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
     2221 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
     2281 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
     2341 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
     2401 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct ggggaaaaag
     2461 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
     2521 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
     2581 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     2641 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     2701 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     2761 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     2821 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     2881 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     2941 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     3001 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     3061 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     3121 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     3181 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     3241 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     3301 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     3361 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     3421 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     3481 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     3541 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     3601 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     3661 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     3721 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     3781 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     3841 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     3901 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     3961 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     4021 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     4081 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     4141 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     4201 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     4261 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     4321 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     4381 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     4441 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     4501 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     4561 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     4621 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     4681 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     4741 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     4801 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     4861 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     4921 gttgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     4981 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     5041 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     5101 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     5161 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     5221 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     5281 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     5341 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     5401 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     5461 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     5521 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     5581 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     5641 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     5701 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     5761 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     5821 aacataaaga acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa
     5881 atatcgacag tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt
     5941 tgtaaaatca aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac
     6001 ttcatactaa aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc
     6061 ttttcccacc acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa
     6121 ttcttctctt tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg
     6181 ttcatatgga ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt
     6241 tcatatgctt ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt
     6301 tctactggga tactataata acttccttca ccattattga atcggtgaac gtctttcttt
     6361 gctaaaatac catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca
     6421 tagtaaatca cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc
     6481 atgaaaatcc cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa
     6541 tcgatacaga ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt
     6601 tattttgtat catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt
     6661 gttttttata ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca
     6721 aaaaagaagt tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt
     6781 ttttctttta ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg
     6841 ctttcagtaa tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc
     6901 cctcgcatgt ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc
     6961 gttttttcta ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt
     7021 ttaattctat aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt
     7081 cgatcaggct tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta
     7141 atacttttcc tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt
     7201 taagttatac gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg
     7261 aactaatcag ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt
     7321 ctgctcttct gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata
     7381 gctgtataat tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc
     7441 tgtgacaggg aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt
     7501 ttttcctttc cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc
     7561 aataattgct aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat
     7621 tttctattcc tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata
     7681 cgacataaga agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc
     7741 ccataacgat caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg
     7801 gatctccagt ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga
     7861 tttttttcag catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg
     7921 cataggcact atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt
     7981 cattgtcctt tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt
     8041 caactgctac catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt
     8101 attgtaacat ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa
     8161 caaaagcaat ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta
     8221 atcccattat ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca
     8281 ttctgttaca aaaaacgtgg atttgtcata aattgtcatg cttcttttac ctatgaaata
     8341 ttttcacgtg ttaaagtatt cctcgttgaa cacaacaaat aaaacttttt aacgaataaa
     8401 ggagattttt catgacatca cttaaaactt tactttttgg aacaactttg gctgccggcg
     8461 ctgcattctt catgggaacg actgctcatg cggacgaagc ttataccgtt caatcaggtg
     8521 atactctatc aacgatttct caaaaatacg ttggtgataa ctccttgatc aatgccattg
     8581 cagaatcaaa ttc
//
LOCUS       DAIGQM010000085         8517 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.088, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000085 DAIGQM010000000
VERSION     DAIGQM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.088"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            166..360
                     /locus_tag="NOA48_002431"
     CDS             166..360
                     /locus_tag="NOA48_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790662.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            629..928
                     /locus_tag="NOA48_002432"
     CDS             629..928
                     /locus_tag="NOA48_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790663.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1025..1459)
                     /locus_tag="NOA48_002433"
     CDS             complement(1025..1459)
                     /locus_tag="NOA48_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0790664.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1691..2401)
                     /locus_tag="NOA48_002434"
     CDS             complement(1691..2401)
                     /locus_tag="NOA48_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0790665.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2391..3251)
                     /locus_tag="NOA48_002435"
     CDS             complement(2391..3251)
                     /locus_tag="NOA48_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCI0790666.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3256..3894)
                     /locus_tag="NOA48_002436"
     CDS             complement(3256..3894)
                     /locus_tag="NOA48_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCI0790667.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3909..4208)
                     /locus_tag="NOA48_002437"
     CDS             complement(3909..4208)
                     /locus_tag="NOA48_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0790668.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4251..5735)
                     /locus_tag="NOA48_002438"
     CDS             complement(4251..5735)
                     /locus_tag="NOA48_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0790669.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5755..6216)
                     /locus_tag="NOA48_002439"
     CDS             complement(5755..6216)
                     /locus_tag="NOA48_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0790670.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6234..7301)
                     /gene="ulaG"
                     /locus_tag="NOA48_002440"
     CDS             complement(6234..7301)
                     /gene="ulaG"
                     /locus_tag="NOA48_002440"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCI0790671.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7519..8289
                     /locus_tag="NOA48_002441"
     CDS             7519..8289
                     /locus_tag="NOA48_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0790672.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
BASE COUNT         2667 a         1754 c         1359 g         2737 t
ORIGIN      
        1 agaacaatag ccttttatta tatatattat tcaaattagt tatatcgagt gaaaaaaact
       61 ttcaaattga ttctttttat ttatcataaa gatatagata cataatcatt ttcacttaca
      121 tatatttgaa tattaactaa aaacagcaag aaagaagagg atcaaatgta ttatgtagaa
      181 gtaaaaacaa aaggcgtcaa aaacaaacaa tatgtgaaag gtatcagtaa cgaatatcct
      241 ttacttggtt catggaaaga agctgctcct ttttccaaac catgtgccat aaaaataaag
      301 aacgagctag aaaaagaact gacttgtggt aaagctgttg tagatatcat cgaaaagtaa
      361 atccaatgta tagaaaggaa gatcacacat gaaaagcgac gtacaaattg ctaagattat
      421 agaattagaa gaagaagacg cagtgttgac aattgaaaaa aaataaatgt ttgtatacca
      481 tatgattatt tcaatatgta tcctggaatt ggagatctcg tagagctata tcaagatgaa
      541 tcaaatatac ttgtcattca tcatgaaata tagagactta taaaattgtt tatttttata
      601 atgtatcagt atagaaagga aataaaacat ggattatact gttgaatttg acagtgaact
      661 acttaagcaa tttccacaag aagaacattt catgtataaa gaagcaattt cccacaaagt
      721 gacagagtat ttggagcata atttttttcg tataaagcca gtgcgtactc gttcggcaaa
      781 aggaatatac gagatgaaag tcaaaattaa taaaaaaaat tatcgcatag catttgcttt
      841 aaaaaaaaat catgtgttca ttttttatat tagttcgaat ttgcaaaaaa ttgtatttga
      901 taaagaggtg agtaaaaaaa taaaatagct gagcattgga ggatagattg agtgatacta
      961 agtctatcct cttgtttttc taaagaacta agctagaatt ttttcttttg tacgttatta
     1021 tatgttattt gtcattacca aaaagcacct tttttcttct agtatctatg acataagaaa
     1081 taccacccat ttcctttact tgaacaaatc ctactgattc ataaaatttt tttgttttct
     1141 cagtatcatc tgtcaataat tcgatttgga ctggtccata actagtgatc ttctccaaag
     1201 cttcattcaa aagcactttg cctattcctt ggcgctgata cctcggatga atgaggatat
     1261 cttgaataaa tgcgatcgtc gcaaaatcag tgatccaacg aacgattccg ataatcttcc
     1321 cttccccatt acgctttatc agagattcag attgttcaaa tgctctagct aaccttgcag
     1381 tgtcttttgt gtaattcgtc caaccaacgc tcttatataa ttcagaaatc tcatcgatca
     1441 taagggaatc aatattcatt tttttcttcc tttcttatac aattctccct ctaataatac
     1501 agttctttga ctatttaatc tatcacatat aactctcctg taaagattct ctcgattcct
     1561 taaaattcct ctttcctttt agaatgcata ctttttgata aataaaaagg ttgtgataaa
     1621 ttttcttcac aacctctgtt tctctctatc aagtgttatc ttttaatttt ctacccttac
     1681 cctagcatct ctattgcccg tagtatgcat actttccatg tttgcgaaaa taatgtttat
     1741 ctagtaaata ttgcgggatt tcacatatat tggggttgat cagctcgttt tctttggcca
     1801 tcagacaaat ttcatctaag atcaaactgt tttctactgc tttcataggt gaatcccccc
     1861 atgtgaacgg tccatgtcca tagacaagta ctccagggac ttcgtttgga tctaattttc
     1921 tttccttaaa cgtctcgaca atcacattcc ctgtatgaac ttcgtaagct tctcttactt
     1981 cttctttcgt taattggcgt gtacaaggaa ccttaccata aaaagcatca gcatgagtcg
     2041 tgccataagc tggcaaatcg cgtcctgctt gcgcccacat gacggagtgc gtggaatgag
     2101 tatgagtaat agcagttata tcttcaaaag tttgatacaa aacaacatgt gtggggagat
     2161 ctgaagatgg ttttaagcta tcttcttcta ttatatttcc cgacaaatct gttaccacca
     2221 tttgatctgc ttgcatgcat tcatatctga caccgcttgg cttaatgacg atgactccta
     2281 gctcacggtc cacttcactc acattgcccc aagtcaattt gactaatccg tatcgcggca
     2341 atgccagatt tgcttcaagg acacgttgct tcattgctgc aattttttct tcacaagaca
     2401 tcatagccag cctccttcaa tttagaactt aagtagtctt ttgcctgctg gatttctctt
     2461 cgaaagtctt ggcttttttc actccacatt tcaatcagaa atgttccatc ataatctaga
     2521 cgtttcaaat gtcttaataa tccaagaaaa tcaacacaac cgctaccaaa aggaacatca
     2581 cgaaactggc ctgaatattc ttttgttaca gggtaagtat cttttaagtg gatagcagtg
     2641 atataatcga tccctttctc aagttctcga gccggattat tttccggcca tgcggacaaa
     2701 ttgcctaggt ctggatatac ttgtagaaaa ggtgaatgaa tctgttcttt gatttctaaa
     2761 aattttgaaa tggagttcat aaatggatca tccatgattt ccacggaaag aatgatgcca
     2821 tatttagaag cttcctttac gctttctttt attccttcga taaagtcttc tctggaattc
     2881 attgatttct cttcataata aacatcgtat ccagctattt ggattacttt gacgcttaga
     2941 ttatgcgcca aatggattgc ttttttcatt agttgtttcg ctgctttttt cttttctgga
     3001 tcagcagaac caaacggaaa tcgccgatgc gcacttaaac aaatcgaatg gatacgtaca
     3061 ccggagctga acatctcttc tctcagctca gctatctttt cttcagacca atctaatcgt
     3121 gctaaccgct catccgtctc atcaatcgac atctcgataa aatcgaagtc catttctttt
     3181 acaagggaaa aacgttcttt ccatgaaata tctttgggta acgctttttc ataaatccca
     3241 atttgagcca tttccttacc cccagatacg aatgatctca tctttgaagt tttgtgcggc
     3301 cttcatcgga tcatttgctg ctgtaatacc acgaccagtg ataaaggtat acacatcgat
     3361 cccttcaaat aagtgtaatg tgtgtggatt taatccacca gttacagaaa cattaaagcc
     3421 tagttcaatc agttttttga tcttcgataa atctttttca ccccaagttt caccagataa
     3481 cagcgcatca cggctttgat ggtagattac ctgccggata ccgatgttat gccaatccat
     3541 ggcttgttca aaagtccaat tgccgtagag ttctacttgc aattcaccta tttctttttg
     3601 tgctgcctcc atagttggaa tcgttgcaca acaaatgact gtcatccagt ctgctcctgc
     3661 ttttgcaaca ttactcgcca ctgttcctcc agcgtctgca catttcgtat cagcgactag
     3721 ttttttatct gggaacatac tgcgaataca gcgaatcgct ttttgtcctt cctgtaagca
     3781 aagaattgtg cccacttcaa taatatctac tacatcacca actttcataa catctcctaa
     3841 tgcatgttct aagtcattgt gatctaacgc aatttgcaaa ttcggcctgc tcatcttagt
     3901 tccttccttt acttgttttt ttggtaccac tttgtttcag caaatttttc actgatttct
     3961 ttgactgaca tcacattttt gataccgata actgtaactc cttttttctc tgcctgagta
     4021 aacatattca aaaaattgac tggcgtaaaa actacatcgt attggccagc tgaacttttt
     4081 ccctctgaaa tggcacaatg atggattttg gtaattggta cgtttagttc tttcattgct
     4141 ttttccacac ttctcatcat catcaagctt gttcctgatc catttgcaca cgatactaaa
     4201 attctcatct taatccctcc attatgagtg ttgtctaatc agattttctt ttatactctc
     4261 tgcttttctg catatgtgtc atagtcttct acaatcaaaa aataaccatc aggatttttc
     4321 cgatattgta actgcggaat agccaataaa ccaatgacaa ctacggcaat tccagcataa
     4381 cctaggactt tcatgattac tgtaaacaat ggccaagctg ttgcccagtc gaacatcccg
     4441 atataaccac cgtatgttga catcccaatc catgtagcga ataatgctga accgcctact
     4501 tgtatgattc ctgaaagaaa cgggaacagg caagcggctt tgaatccacc tcggttattg
     4561 gcataaactg ctataacggc attatcaaag aacaacggaa tgaaaccggc tatgacgatc
     4621 gttggtgatt tcaataaaat cagtaaacca atcatcaaaa actgtcccaa agcaccaaac
     4681 aagaacccaa tcgttaccgc atttggcgaa ccaaagccaa aagtagcagc tacgtcaatt
     4741 cctggaacag ctcctggtaa aatcgtgttt gagattcctt ggaaagattg agttagttca
     4801 tcgacgaatg tccgaacacc taattgcaag atcgccagat ataccgcaaa atttaaagaa
     4861 gtcgtcataa tgtagaataa gaaactctgc ccttcttgca tgaattgcgc ttgaatcaaa
     4921 taatctttgc ctagtacaat cagaatgatc ccaaagaaaa atagcatgag taacgaagta
     4981 gcaaccatat tctcattgaa aatcgacaag aatcctggta atttgatatc ttcaattttt
     5041 ttgtcttgct tgattgatct atttttcttt tcatcccgct ttttcatcca ctcagctaat
     5101 tttgcaaata taaagattcc gaacatttgc tgatgtgcca ctgcaaatcc ggcaccttct
     5161 gtcaattcct gcgtgattcc tactgttaag ttagaagcta ctgtccaata acaacctaaa
     5221 atcagtccca taaaaatcaa tgcttgtatc ctacctagat caggaaagca aaacagtaaa
     5281 atccaaaaag cggtagctgc ttgttgaacc tgaacgtttc cggtagtgaa aacggaacgc
     5341 agtttcgtat atttctgaaa acggactaat aagatattta aaacaaatgc aatcagtaat
     5401 aaaatcatca catctccaaa ggtacggcca aatgtctcca ttaatccagc atccacagca
     5461 ttttgtccaa aataaggatc tgtaaccatg gcatccaaat tgaaccgttc ctttagtcca
     5521 accaagattg gccgaaaatt attgaccaaa ccaccagagc caacagtcaa aataaagtaa
     5581 ccgaccgttg cctttaagaa tccagcgatg cattcatgaa gcgggcgttt cagcaaaata
     5641 tagcctaata acacgataaa accaatcagg tatgctggct gcgtcaagat atttgttgca
     5701 aaatacgtcc aaatgcttaa caaaaattcc cccatctttt ttctcctcta tcaattaatt
     5761 atattctgcc atcacaactt ggtaatcatc gatggagttc gtagagatga gacgctcaac
     5821 caatccatct gtcattaata attcggataa tttttggata ttttctagat gttcttctgg
     5881 atcttttgct gcgagtgtaa aaaacaaact agccgttttc tcctcattct ccccttcact
     5941 ttcaaaacgg attggctgtt tcaacttggt aaatgaaata gctgttccaa aaacaccatc
     6001 acttttttct gaagaatgcg gcattgctac ttgaggtgcg atcacaatat aaggaccgta
     6061 tttttctaca caatggatga tctcctccac atacgtttca tcaataattt ccttatcgat
     6121 caatacaaga cagctttcgg cgatagcttc acgccaatcc gtgatttctt tatctgggta
     6181 atgaatcaat tgatggtcaa aaaagtattt cagcaagaaa ctccccttct ttcttataaa
     6241 aacgacggaa acggtgtatc attttcaatc gagaagacat cttcaaatcc tcgataaaaa
     6301 ttaaactcaa gatcatcttt gtttgtcgga tagatgaatt tcccgcctac ttgccagata
     6361 taaggtttaa atccatactt caggcgatcc tttttgaatt tccaaatttc agtgatctct
     6421 tttggatcag ccataaaatt agaccaaata tcgtagtgga caggaatcac tacttttgca
     6481 ttcaatgact ccgccatgcg cagcatatca acagaagtaa ctttgtctgt tatccctcgt
     6541 gggttttcac cataggcccc taaacagaca tcgattttgt gttcattacc atgtttggca
     6601 aataaattgg agtaatgtga atctcctgca tgataaagat tccctcctga tgtttcgaat
     6661 aaatagttta ctgcaatttg atccatctcc tgaggcattt ttccttttaa tacctcttct
     6721 ggatcttcac aagtgaccaa cgctgtccga tcaaacgctt ctaaagctac tacattgatg
     6781 tctttgattt tgactgcatc acctggcttt actgtaatcg ttttttcttc aggaattccc
     6841 catttttgcc acgtgcgaac cacttctttt ggcccaatga atgttgcttc aggacaattt
     6901 tgatgaactg ctgcggctgt atggatatct agatgatcgg aatggatatg tgtaacgatt
     6961 aaagcgtcta cattttttat cgcaaaagga tcgattacga aaggctgagt acgtaaatta
     7021 ggctgcatat tttgaacgcc actcatacgc atcatctgat ggcctttttt catcatgcca
     7081 ttcccatgac tacgttttcc cgtcccacac catagatcac ataaaatatt cgttccttca
     7141 tgacttttca gccaaattcc cgtacagccc agccaccaca tagcaaaagt tccaggatcc
     7201 actacttctg tttcgatttc ttcattcaag tatgtgcccc actcaggaaa tgtttctact
     7261 aaccactttt cttttgttac ttcattgaca gttttactca tttgcttgct ccccccatat
     7321 cgttgttcca acttacaagt aaatattaat gtgtatcagc atccatgaaa acccttttat
     7381 atgaccgttt gttttttata tgattttctt tcagtaatca atgattgttt cagtataata
     7441 aagacagata tgaatgttta aatgaacaac tagtcaaata aatccatgga tcaagatgtc
     7501 cctcaggagg caaaagtcat gaaaaactca cttgtcaata ttgaaaaacg tcaaaaagaa
     7561 attttggaac tgcttcagca gactgaacaa ctatcaactt tcgaattagc tgaatccctt
     7621 gatgtatcta ttagtacgat acgaagagat ttaaatttat tagaagaaaa aaacgagatc
     7681 atacgcaatt acggttattg ttcttataat tacaaaaacc agactgattt tgatcaatct
     7741 ggtcctgaaa ggattaaaca agcgattgcc agagaagcta gtaaatacat taacgattat
     7801 gatacgctgt ttatcaattc tagctcgact gcgttgaaaa cactggattt tcttcaatct
     7861 aaccatttga cagtcattac aaacaacgtg aaaatcaatt actctccgca caaagataat
     7921 tgtagttata ttttaactgg tggagagatg cgctttccaa aagaagcact agtgggcgac
     7981 atcgcattaa atacgatttc ttcagtcaat gcagacattt gtatcattgg ctgtagcgga
     8041 gtcgatgtag tacatggggt cacaacaaag atattaaatg aatcaacgat caacgaaatg
     8101 atggtcaaca agacaatcaa atgtaagatt ttagtcgctg atcatcgaaa aatcggactg
     8161 acatcaaagt tcaagattgc tgatatttca gtctttgatt atttgatcac tgataaattt
     8221 tgttctgaaa aagtattaga ggagatcaga aatacgggga taaaaaccat tcaagtagat
     8281 tcattttaag aaccaggacg taaatatgta aataggatta tcaaaaaaat gaataacaaa
     8341 tttatcgata aatgaaaaac acgctacgct caaattgata aaggaatccc aagatgtatc
     8401 catccaatcg ataccatcat aatctattgc ttcttttata accgttatat gttgcctaaa
     8461 taggaatcaa acaatatcga aaaaaggagg tatgacaaaa gtcacacctc ctttttt
//
LOCUS       DAIGQM010000086         8229 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.089, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000086 DAIGQM010000000
VERSION     DAIGQM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.089"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            329..1252
                     /gene="truB"
                     /locus_tag="NOA48_002442"
     CDS             329..1252
                     /gene="truB"
                     /locus_tag="NOA48_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCI0790673.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1256..2197
                     /gene="ribF"
                     /locus_tag="NOA48_002443"
     CDS             1256..2197
                     /gene="ribF"
                     /locus_tag="NOA48_002443"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCI0790674.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2592..3377
                     /locus_tag="NOA48_002444"
     CDS             2592..3377
                     /locus_tag="NOA48_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0790675.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3390..4241
                     /locus_tag="NOA48_002445"
     CDS             3390..4241
                     /locus_tag="NOA48_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCI0790676.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4365..4817)
                     /locus_tag="NOA48_002446"
     CDS             complement(4365..4817)
                     /locus_tag="NOA48_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790677.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5282..5650)
                     /locus_tag="NOA48_002447"
     CDS             complement(5282..5650)
                     /locus_tag="NOA48_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCI0790678.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5800..6282
                     /locus_tag="NOA48_002448"
     CDS             5800..6282
                     /locus_tag="NOA48_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCI0790679.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6319..7329
                     /locus_tag="NOA48_002449"
     CDS             6319..7329
                     /locus_tag="NOA48_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCI0790680.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7444..8157)
                     /locus_tag="NOA48_002450"
     CDS             complement(7444..8157)
                     /locus_tag="NOA48_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790681.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2785 a         1337 c         1667 g         2440 t
ORIGIN      
        1 attaagaaac tgaaaaaata aataaaaaaa aacggaaaaa agactggaag aatggacagt
       61 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
      121 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaaaacata
      181 acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
      241 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
      301 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttaactttat ggaaagaacg
      361 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
      421 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
      481 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
      541 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
      601 agatatgtct ttatctgaag aaaaaataga tgaagtgatg gcttcattta ttggtgagat
      661 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
      721 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
      781 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
      841 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
      901 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaaaga
      961 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
     1021 gctgccaata gaaaaaggag tgaaacgatt caaacgagta gatattactg atgaagtatg
     1081 gcagaaagta aaaaacggta tgagacttaa ttatactgta tttgcgctcc cagaaatgcc
     1141 gtcagaagaa attgctttgt tttataaagg caaagttgtc agtatctatc agccaaaccc
     1201 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
     1261 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
     1321 agtactagga ttttttgacg gcgtgcatat tggacaccag aaagtcataa agacaggtat
     1381 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
     1441 gattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
     1501 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
     1561 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
     1621 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
     1681 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
     1741 aggtgaaaaa atcagctcta cccgtattcg aggattacta gacagcggac aagtaaaaga
     1801 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
     1861 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cagttcattt
     1921 gcctaaagaa ggtgtttatg tatcggaaat aaaaattggg gaaatttggt atccagccat
     1981 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagaattgta
     2041 tattttggac tttaatcaag atatctatgg tgaacatgtc gcagtacgct ggaatcaatt
     2101 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaagagga
     2161 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
     2221 tttatgtata actagcaatt tcaataaaat gggtgataaa taagcccagg aaaggggctg
     2281 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
     2341 tcggaaataa gccgaaattt cacaaaaatt tgagaagtaa tttttgtaaa ttacttctta
     2401 tttcttgaag ctggccactt ctgtcacaac ctctttcttt atagaaataa aaggacacta
     2461 gcaattcatg aaaacgattg ctaaagcgta tcatttgctt tagactatat atcttggtgt
     2521 acactcactt taagacggaa ataaaagtta tccgtaataa caggtttagg tatgaaaaag
     2581 gagtgggtac tatgtataag gaattagaaa acaaagtcgc agtagtaact ggtggctcaa
     2641 aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca
     2701 actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg
     2761 gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag cgtttacttg
     2821 atacggcttt agaaaatttt gggacactgg acgtttggat taataatgct gggatggaaa
     2881 atcagcatcc aacccatgaa cttagccttg aagattggga aagagtatta aaagtcaatt
     2941 tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag aatgataaaa
     3001 aaggaaatat catcaatatg tcttctgttc atgaacaaat cccatggcca acgtttgctc
     3061 attacgctgc ttcaaaaggc ggagtaaaac tattcaccga aacggtagca atggagtacg
     3121 caccaaaggg aatcagaatc aatagtatag gacctggtgc tatccgtaca cctattaatg
     3181 cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc ccactaggac
     3241 gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca gacgaatcca
     3301 gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat ccttctttcc
     3361 aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg atcccggcag
     3421 ttgggtgggg gatccagcca ctgattttga aaaagattgg tggcagacca acaaatgaga
     3481 tattaggaac tggtattgga gccgtgctcg ttggcttact tgttcaatta ttcgcttctc
     3541 cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca ttctgggtca
     3601 tcggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa acgatgccaa
     3661 tttcgactgc attacagtta gtcggaacct cattgattgg tgtcttcgct tttggagaat
     3721 ggtctggaag tatgggaaaa atcattggtg cagcagcaat cattcttctt gtatttggtt
     3781 ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca aaaggaatca
     3841 gtctattagc atcaacaagt attggttatt gggtttacag tgcattgccc aaactagttg
     3901 atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta ggggcagtga
     3961 tttatgtgat tttccgaaaa ccaaccgcat tttctgaaga caagagttgg aaagcaacaa
     4021 tagttggagc catcttcagt gtgtcagcat tggcttatat tttttcagca aatgaaaatg
     4081 gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca ttaggcggta
     4141 tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt atcggattat
     4201 tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga tggtaaaatc
     4261 tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa aaaatagcgc
     4321 tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga tacaagtgaa
     4381 atatctgtct gcatcaataa tttttcattg atccattgac taaaatttac gacatgattg
     4441 aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga
     4501 cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc tcggatttga
     4561 ttgattgctg taaaatcacg atactgaagg ttgaaacgca tcgtgattgg tgcatttagc
     4621 atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa
     4681 agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag ttttccttca
     4741 tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa ttcatttact
     4801 gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac ttagttgata
     4861 tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt aaaaatcaag
     4921 tcagaaaatt ctaacttttc tttctctaaa gaaattcgtt ctctcctaaa gtgatattat
     4981 atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata ttttctcgta
     5041 ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt tactaagtgg
     5101 aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc cttataaaaa
     5161 tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat aggattgaac
     5221 aaaacctgta taagctgatg aatagtttcc tcgccagtaa aaggtttatt cgtataaagc
     5281 tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa atcaattgtt
     5341 caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta tccgtatata
     5401 cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt tccggtgcga
     5461 tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg tcagtaaaca
     5521 taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt atcttagcaa
     5581 aaaggtcttt gatcttttgt tgatgttctt tttctttgat ctgattgatg atcggctgaa
     5641 atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca gaaaaacaat
     5701 agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata tttatatgat
     5761 aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt ggcaaagaaa
     5821 ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta tacaaatgaa
     5881 gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa aagcttattc
     5941 ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa acaaacggat
     6001 ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg
     6061 gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga aaaacagatt
     6121 ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc accaggtaga
     6181 ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca gctacttgag
     6241 atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat
     6301 acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc aacgattggg
     6361 gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga atcagcttta
     6421 aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg gacgcaagat
     6481 aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat gatgcaagat
     6541 gaaaatatcc aaatgatctt tccgccttgg ggaggagaat tattgattga gattctcgat
     6601 tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga tattagtacg
     6661 ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac caaccttatt
     6721 gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca
     6781 agagaaggag aatcgattct acagcaacct tctgaaaagt atcaaaaaga gtggccccat
     6841 gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca atcagtcagc
     6901 ggagatgcag taaggatgaa gggacgatta ttaggtggct gtattgatac gatcagtcat
     6961 ttaatcggta ccccttatgg agatgtccaa tcttttaaaa gaaagtataa tgatggaaag
     7021 ccgatcttgt ggtttctaga aaattgtgag ctatcgtcag ttgatttaag aagatcactt
     7081 gttcagatga aactggcagg atggtttgat ggcagctcgg ggatcatgtt cggtagaagt
     7141 gcagcagagg atttgttaga ttataaaatg aaggatgtat atgaagatct gtcaaaggaa
     7201 ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca actgacattg
     7261 atcaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt tttgcaaacg
     7321 tttatttaaa aaattttttc ctgccttgga gtttatcaaa gaccaacaaa tctaaataga
     7381 aaagaaaatg aaagaagctg acagtatttt gccagcttct ttttgtatga tctattagaa
     7441 attttaatta tccataacta tcacattgat cagctgtttc acatcatttg gattacctgt
     7501 aggaatagct actacagatg cattatcaat aatttcttga gttgtttctc taatgaacgc
     7561 tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat aactagtgat
     7621 tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt tcccagtgag
     7681 cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga taggtgttcc
     7741 tgcaggataa tgaataacat gtagttcgaa atcacccgat gtatctctaa aagtattacc
     7801 tctaattgct agccaaacac gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg
     7861 atctattgac tgagaagact gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt
     7921 ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac tgcttgttga
     7981 agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag ctgaactggt
     8041 ttgtttgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt tactaggaga
     8101 cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact ttttcatata
     8161 aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt gaatccgtaa
     8221 aaccttgtc
//
LOCUS       DAIGQM010000087         8114 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.090, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000087 DAIGQM010000000
VERSION     DAIGQM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.090"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..280)
                     /locus_tag="NOA48_002451"
     CDS             complement(<1..280)
                     /locus_tag="NOA48_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0790682.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKNKNKKSFYSWKMDETYIKIKGKWHYLYRAI"
     gene            608..835
                     /locus_tag="NOA48_002452"
                     /pseudo
     CDS             608..835
                     /locus_tag="NOA48_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            961..1932
                     /locus_tag="NOA48_002453"
     CDS             961..1932
                     /locus_tag="NOA48_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790683.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            2073..3386
                     /locus_tag="NOA48_002454"
     CDS             2073..3386
                     /locus_tag="NOA48_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0790684.1"
                     /translation="MKRRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNDKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIISLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3429..4295
                     /locus_tag="NOA48_002455"
     CDS             3429..4295
                     /locus_tag="NOA48_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0790685.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4292..5140
                     /locus_tag="NOA48_002456"
     CDS             4292..5140
                     /locus_tag="NOA48_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0790686.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5154..6626
                     /locus_tag="NOA48_002457"
     CDS             5154..6626
                     /locus_tag="NOA48_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HCI0790687.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWINDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMTAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKGLVYDQHYLRLEINLKQATKLELHYAKGPHHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            6643..7515
                     /locus_tag="NOA48_002458"
     CDS             6643..7515
                     /locus_tag="NOA48_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0790688.1"
                     /translation="MIYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(7749..8114)
                     /locus_tag="NOA48_002459"
                     /pseudo
     CDS             complement(7749..8114)
                     /locus_tag="NOA48_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2488 a         1420 c         1719 g         2487 t
ORIGIN      
        1 cgatggctcg atacaaataa tgccattttc ctttaatttt gatgtacgtt tcatccattt
       61 tccatgaata aaaggatttt ttatttttat ttttccaaat ttgatagagt agtttgccat
      121 attcttgcac ccaacgataa atcgtcgtat gagaaacgtt aatgccacga tcatataaga
      181 tttcttgaac ttcacgatag ctaaggttat aacgaagata gtatcccacg gctacaataa
      241 tcacatcctg ctgaaattgc tttcctttaa aatgattcat cgtcattcct cctgctatct
      301 ttttctatta ttctacctta tttgatagta gatttaaaac tttgcaacag aaccacatta
      361 attttgttgg caaatatagt ttccgctatg aaaaagaatt atcgaatgga atactacgtc
      421 cgttaaatat agagaattat tgagaatgtt cgtcttttgg ttcctaccgt gcattttcgc
      481 acggatgttc cagatactat ttttgaatgt ataaaattga aaacacaaga atcctattaa
      541 atcaacgatt cttgtgtttt taatttttca ctaccgtgca ttttcgtttc tatgttccat
      601 gtaccccaat cttgaaaaat taattaaaga cttatataaa gccattgacg acttagtcgt
      661 ggtgctaccg gagtatcaat gtttaaccag tatcccaggt attggtcctg tttaggctgc
      721 tggaatactc gctgaaattg gtccaattga acgtttttct gatgaaataa aattgacaaa
      781 gtatgccggc ctatattggc gacagagtca atccggtaaa tctgaatacg aaaatttttt
      841 tacgaaaagc ttcacgtcta atatctattt taaaataaaa atattcctgc taatttggaa
      901 tcgtttcctt cttttggtat aataatacct gaaattcttt tgagaggagt tgttcgtgaa
      961 gtgaaaacta ctatgaagga tgttgctgcg ttagcaggag ttggtgtggg tacggtatct
     1021 agagtaataa atggagtaaa ggtgaaagag gttaccaaag aaaaagtaat ggctgcaatt
     1081 agtgagctta attatgagcc tgatgaatat gccagaggta tgaaaacgaa tagcagcaat
     1141 acaatagctc ttattttacc tacgatttgg catcccttct tttccgagtt tgcctactat
     1201 gtagaggaag ctctcagcca aaaaaattat aagctttttt tgtgtaatgc gaacggcagt
     1261 gcggaaaaag aaaaagaata tatccaaatg gtcaagcaga gtaaagtaga cggaattata
     1321 ggtattacct attcagacat tgataaatat gtatcatcaa atttaccatt tgtcagtata
     1381 gaccgccatt tttcggaaca ggtttcttat gtaacggcag ataattattt aggtgggcaa
     1441 attgccgctc aagaactact tactcgtaac tgtaaaaact tgtgctatgt tgggggtgtt
     1501 tcaccttacc ctaacgaaac aaacaatcgt aaagctggtt tttacaatat ttgtgaggaa
     1561 aataaaatag ctgtgaaggt attggatatg cctgaaccaa ttagcaattt ggaggaacaa
     1621 ttgctcgctt ttttttcgga taatcctgaa attgatagca tttttaccat caatgatttc
     1681 atggctttgg atgtgataaa agcccaaaaa aaactaggga aggaagcacc taaggatttt
     1741 caaattattg gttttgatgg agtcaagcta tcgttgcaaa aagactattt actatcaacg
     1801 attgtacagc cgatagagga aatggccaag gtttcagtag aaacactcat ggcgatgatt
     1861 ttaaatgaag aaccgcctaa gcgtgtggta gtaccggttt tctttcacgc tggagaaacg
     1921 actaaagagt aaaaaaccgg tttataacga ttttttttga gataggttga cagaaagtgg
     1981 tttcaatgat atcttaaaac caattaattg gaaacgttac caattaattg gaaaataaaa
     2041 cggaaacgtt tcaaaaaata ggaggaacat cgatgaaaag gagaatgtta gcaattgcag
     2101 caattttagc attaacagct ggaggacttg caggatgtgg cagtaaggag aaaagttcag
     2161 gcagcagtga ttcaggagaa attaagattt gggttcagtt ttctgatgaa acgcctgaag
     2221 gaaaagcttg ggcagagatt gtgaacaatt ttaatgatga atacgagggt gaatataaag
     2281 ctgttactga gtatattcct cgtagcggaa gcggcggtgg atatgaggat aaagtaaatg
     2341 ctgcaattac aaccaatacc cttcctgatg ttattacgtt agatggaccg aatactgcag
     2401 cttatgctca ttcaggagtc attgctccat tagatgatta tttgaaagat gcggacatgg
     2461 atgatgtatt agacagcatt attcagcaag gaacctacga tggcaaaatg tatgcgtttg
     2521 gtttctcaga gtccagtgtg ggtgtctatt acaataagtc gttgttcaaa gatgctggaa
     2581 ttacagaaga tcaattgccg acgttagaag atccttggac ttggacggaa tttcaagcaa
     2641 tttgccaaaa gctgactgat aaatacaaaa cgcctgcaat tgatatgcaa atggcgtcgg
     2701 gagacgaaat gctgacctac gcatatacac catttgtatg gtcgaatggc ggcgatgtcg
     2761 ttaatgctga tggaaccaaa gccgaagact attttaacga taaaaaatcc gttgaagcgt
     2821 tggaatttat tcaagaattg gttgaaaaag gttacaccac aatcagtcct attgaaaaag
     2881 gatttgaaac tggcaaatat gccatgctgc tgagcggttc ttggacaatg gcagatttag
     2941 aggaaaacta tcaagagatt gattatggta ttttgcctta ccccgtttca gatgcaactg
     3001 gggagttagt ttcaccaacc ggcagctggc agttagcaat gactgagaaa acagagaaaa
     3061 aggatgcttc tgcggccttt attaagtttg caaccagtac agaatctagt cgtattatta
     3121 gtttagggaa cagtgttcta cctatcagaa attcaacagt tgatttaatt aaagatgaag
     3181 tgtcggaagg aatgcaggta ttaattaagc aaaaccaaat ttctggacat gcccgcccag
     3241 tggttgtagc ttatccgcaa gtatctagag cattccaaca agcagttcaa gatattagct
     3301 acttcgagga aaacccagat gtacaaaaag tagcagatag tcgcgctgct gaaatgcaac
     3361 aggcaattga tacttcacta aaatagaagt ttctaaaggg ggccaatcaa gtgttaaaaa
     3421 aaccgacaat gaaagacaat ttgataggtt acggctttct agcgccagct ttgctgctgc
     3481 tgacgatttt tctgatcata cccgtaatca tggtaattta ttatgccttt actgattatt
     3541 atttgttaac gccagatgct agacaattta tcggcttaga aaattttaag cgactgttcg
     3601 ctgatccaat ttttgtaaaa agtatttgga acacggctaa atttgttgtt tggattattc
     3661 cggtccaatt aggggcagct ttaggaatgg cacttattat caacaaaaat cgtaaaggaa
     3721 atatcttttt taaagtagcc ttttttgcgc cagtcgtgat gtccttagtc gttatttcga
     3781 ttttatggtt gtacttgtta aatcctaatg aaggtctggt taatacgcta tttgcaaaga
     3841 ttggaattgc ttcgcagcct tttttgacta gtcccaaaca agcaatgtat acgcttgttt
     3901 tcgtatcggc atggcaaggt gcaggatatc agatgctgct gtttttaggg ggaatgcaaa
     3961 atattccgca agacgtttat gaggcagccg aaattgatgg tttttctaag tttcagcaat
     4021 ttcgctatat caccatgcca ttattaaagc ccacggcgat ttttatttta cttaccacat
     4081 tgatttcggc ctttaaacta atcattcagc caatggtaat gactcaaggt ggaccaatga
     4141 attctactat gacaatggtt tattacattt accaaactgg atttacagac cgtatggtag
     4201 gctactccag ctccattgcg ttaatcttta ccaccatgat tggtttaatt acaattgctc
     4261 aaagaaaatt ggtaaaggag gatgatccag catgaccaag aaatttggac cgctaatgat
     4321 cgtagaatat tgtttgctgt tccttttagc ggcattattc attttcccaa tgctgtggat
     4381 ggtagtttcc tctatgaagc ctgaagcaga tgtctatcaa aatttagctt ccttcaaagc
     4441 ttttttacct agtttgaatc cagctaattg gtttaaaact tatcaagaag ttatttcccg
     4501 gttcagtgtg ggaacttatt tattaaacag tattttttat ggtttaacct ttgcctgtgg
     4561 gtcaatcatt gtaaactctt tggcgggttt tgcctttgcg aaggttaatt tttcaggcaa
     4621 gaaaattatc tttggagctt tgttagctct gctgattgtc ccgatggaga cggttttaat
     4681 tccgcaattt accatcgtta attcactagg cttagtgaat actcgcttgg cagtgatttt
     4741 accagcgatg gccagcgcgt ttaatatcta tttgtttaga aatttcttta tcgcgattcc
     4801 agaagaaatc attgaatcag cgaaattaga tggtgcaaat attgttaaaa ttttctttca
     4861 catcatgctg ccaatgtcta aaccagccat agccacagta ggtgtcttat cctttatctc
     4921 cagctggaat gattatattt ggccgttaat ggtcttaact gacagcagca aattttcaat
     4981 gcaagtggca attactacga tcaatactac acagccagtt tatatcaatc aagtgatggc
     5041 tgttttaacc attgcaacga ttccactgat tattgtttat atcgttgcac aaaaatatat
     5101 tctgcaggga cttggcggtt ctggaacggg tataaaatag gagtgaatag tgaatgttgc
     5161 aaaaactttt aaaggccaat gagtttattg agaaaaatgc tcaaacagtc aatcaagaat
     5221 accggaataa atttcatttg atggctccga ttggctggat caatgatcca aatggttttg
     5281 tttattatca agaggagtat cacttgtttt atcaatatta tccttacgat agcatctggg
     5341 gaccaatgca ttggggccat gctaaaagca aggatctaat tcactgggag catttgccag
     5401 tagcactggc accaggtgaa agctatgaca aggaaggctg tttttccggc agtgccatag
     5461 aaaaggatgg caagctgtat ttgatttata caggacacaa tgttgtggaa gggcaagttc
     5521 gacaagttca gtgtttggca gtttcagaag atggcattca ctttgaaaaa tatgccggaa
     5581 atccaatcat cgcagaagat cacttagctt ctgttgcaac gaccgaagat ttccgcgatc
     5641 ccaaagtgtt tcagcgaaaa gaagactatt ttactgtagt cgctactaaa actgcagatg
     5701 ctcgtggaca aattgtgatg ttccattcca aagatttact aacttgggag ttttattccg
     5761 tattgctgga gggaactcca gaacaaggca ttgtatggga atgcccagac ttgtttgaac
     5821 tagatggcaa agaagtcttg attctttctc ctattcaaat gactccacaa ggcaatgctt
     5881 accaaaatac gaactcaact gttgctttca ttggtactgt cgattggcaa acaggcaaat
     5941 ttctagtaga gaattttcat gaaatcgatg gcggtttaga tttttatgcc ccccagacct
     6001 gtgaaaacga agcaggccaa agaataatga ctgcttggat gcaaatgtgg cagcgtaaaa
     6061 tacctacgaa tgatctgggc catggttggt caggttccat gaccttgcct agagagctga
     6121 gggtggctga taatcaattg ttgcaacggc cagtttcatc aatttatcaa gtaattgatc
     6181 cgcaggaaag gattgaatgg gcgaagactg aagagaatcg attcttactg aagggcttag
     6241 tatatgacca gcactattta cgcttggaaa tcaatttaaa acaggcaacg aaactagaac
     6301 ttcactatgc gaagggaccc caccatacat tactgcttaa ctatgatgtt gaacgggagt
     6361 gctttactgc ttccagggaa cacatgccgt atgatttatc aggagctgaa aaggaagtgt
     6421 tgaaaaagcg cagtgtgacg attcctttgg aaaataattg tctaaccatc gaaattttcc
     6481 gtgatacttc agctattgag ctttttctaa atgatcgtct gactatgagt acaacttttt
     6541 atgagacaga aaaaggacag gattttcttt tgctggcaga cagtgaagta accttttcat
     6601 tggaaagcgg cttaattaat ctatagaagg gagagctcag tgatgattta tggtgcaatt
     6661 gaagcaggcg gcacaaaatt tgtgtgtgcc attggcgatg aagaaatgac gatcaaggaa
     6721 agagtgagct ttccgacaac gacacctgag gaaacaatgc ctttagtcat tgacttcttc
     6781 aaacaatacc aagcagattt agcagggatt gggattggct catttgggcc tatcgatatc
     6841 catcgcgatt ccgccactta tgggtacatt acctcgaccc cgaaattggc atggcaaaat
     6901 tttgatttca tcggtaccat gaaaaaagaa tttccgatcc cgatttcttg gacaacagat
     6961 gtcaatgcgg ctgcctatgg tgagtatgtc ttcggcagtg gcaaaggatt gagcagtgtc
     7021 gtttactata cgatcggtac gggtgttggc ggcggtgcct tacaagaagg gcgctttatc
     7081 gaagggttta gtcatccaga aatggggcat atgctcgtcg tccctcatcc aaaagatgac
     7141 tttgctggca gctgtccatt tcatggcaac tgtttagaag ggatggccgc tggacccgcc
     7201 atcgaaaaac gcttagggaa aaaaggacaa gaggttgcag aagatgatcc ttattgggaa
     7261 atcgaagcct cctatattgc tcaatgtgcc tacaatacaa ccttgatgtt ttctccagat
     7321 gtgatcattt ttggcggtgg tgtgatgaaa caacgccata tgctgcaaaa cgtccacgac
     7381 gcatttgcaa aattggtcaa tgggtatgtc gaaacacctg agttaagcaa atatatcgtg
     7441 accccagcat tagaagacaa cgctggaacg ctcggttgtt tggcattggc tcgagaagcg
     7501 gtcttacatt cataaacgaa aaaaggctct tcgacattta gtgttggtag agaaagatac
     7561 aactgaaaat ttagtcataa ccagttaggc agagtgctta actggttttt gttttacttg
     7621 gaagatcaag ccttgaatga gataaattct tgctcgaaag ttatggaaat ttcgatagcc
     7681 gtaggctact tgtattgtgc aatagttttt tacaaaaaaa aggggtgcgg atattttttt
     7741 ggaccttttt aacaaatata tctttgcttc ttccgatatt gaagagggct tagccctcct
     7801 aaagataact taattcgttg attattatac caatgaatat aattatccaa tttgtttata
     7861 aactgattga ttgttgtatt cttccagtca cgttgataaa acatctcgtt ttttaatcgt
     7921 ccaaagaaac cttcgcacgc tgaattatct ggtgaataac cctttttaga catagagtga
     7981 agcaagttgt ctttgttcca atagtccaac taacaatagc accatcgtaa caatcgacaa
     8041 gtggtgataa gtagattttc cctgcgggaa ttctaaattc agtaatatct gttaaccatt
     8101 tttcatttgg cttc
//
LOCUS       DAIGQM010000088         7600 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.092, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000088 DAIGQM010000000
VERSION     DAIGQM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.092"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(943..1356)
                     /locus_tag="NOA48_002460"
     CDS             complement(943..1356)
                     /locus_tag="NOA48_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCI0790689.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="NOA48_002461"
     CDS             complement(1812..2297)
                     /locus_tag="NOA48_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790690.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="NOA48_002462"
     CDS             complement(2436..2651)
                     /locus_tag="NOA48_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCI0790691.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="NOA48_002463"
     CDS             2875..3675
                     /locus_tag="NOA48_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0790692.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="NOA48_002464"
     CDS             3694..5562
                     /locus_tag="NOA48_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0790693.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPTNRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="NOA48_002465"
     CDS             5555..6046
                     /locus_tag="NOA48_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI0790694.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="NOA48_002466"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="NOA48_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCI0790695.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="NOA48_002467"
     CDS             6606..>7600
                     /locus_tag="NOA48_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCI0790696.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1443 g         2236 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccaccaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAIGQM010000089         7581 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.093, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000089 DAIGQM010000000
VERSION     DAIGQM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.093"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..662)
                     /locus_tag="NOA48_002468"
     CDS             complement(<1..662)
                     /locus_tag="NOA48_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0790697.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HD"
     gene            complement(1099..1668)
                     /locus_tag="NOA48_002469"
     CDS             complement(1099..1668)
                     /locus_tag="NOA48_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0790698.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1742..2065)
                     /locus_tag="NOA48_002470"
     CDS             complement(1742..2065)
                     /locus_tag="NOA48_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790699.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2219..3031)
                     /locus_tag="NOA48_002471"
     CDS             complement(2219..3031)
                     /locus_tag="NOA48_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790700.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3385..4233
                     /locus_tag="NOA48_002472"
     CDS             3385..4233
                     /locus_tag="NOA48_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCI0790701.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4378..5319
                     /locus_tag="NOA48_002473"
     CDS             4378..5319
                     /locus_tag="NOA48_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCI0790702.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5309..7480
                     /locus_tag="NOA48_002474"
                     /pseudo
     CDS             5309..7480
                     /locus_tag="NOA48_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2259 a         1507 c         1360 g         2455 t
ORIGIN      
        1 ttgtcatgaa aatcttgtgc tccaccctta gtatttcctt ctggatcgtt tgtcgcacgc
       61 atcatgacgt atactttctt attagggaaa tcacgcatat tgaaagatac atgatagcca
      121 acatttccta aagtattata agcttgattt acgtctggtc tataaatccc atcagctctt
      181 actctagcta gttcttttcc agtattgtag tccataatga aaatatactc gtatttataa
      241 ttagcaatgt gccatccagc tacatgcaag tttgcgtttt cgatttctcc gaactgatca
      301 atgtgggcgt aatttgttcc atctgtcagc gtagaatttg cagcacctgc tcgagttgga
      361 tcaattactg gtttatcctc cgaagtagtt ggattatcat ccgtaaaacc atgagccaaa
      421 tcataggcta gtttttcttt acttacacct atttcagaaa gataaccgta aggatctgta
      481 tgatcgcccc aaatattttg tgttacccat aaatgcgatt tgattcctgg ttggttataa
      541 ggagtgtcta atgttaatgg aataccatat ttcattgctg aatctcttgc caattcaacg
      601 tatactttat agttcttttc aaaagtttct ttatcatgtg tgtgttgtaa ctcgatttgc
      661 acaggacttt tggctcacga ggttgtccta ctctacatct tgctgataga tatgctgaaa
      721 ggaaaacacc aacattatgt tttgcttttt cagctagaac gagacaagca ggaatacctt
      781 tagaagatat caaaggtttt ttaggtcata aagatgtttc cactacacaa gtctatgccc
      841 atatttctcc cgaagtgaaa aaaagatcaa tgaatcaact agaaaactat atagaagagc
      901 aaataaaaaa gcactcaaat tgagtgcttt tttaagctca ctatcactaa aactatcact
      961 aattttattt ataagcgaac atgtttctat cactgatttt ttaaatctag cgaaaaaccc
     1021 ttatcttaaa ggcgttcgtt caattctttg gcaaggtctt caaagcctgg cttgcctaga
     1081 agtgcgaaca tggttttctt atagctcatg tagaaaaatt ttcttgatga tgattttatc
     1141 catcaattga gattgactgt tttgctctcc tatgatttca gctatgattg tccgattttg
     1201 cggttttctt cttaactggt agttgatttt cccagtttcc atcaactcgc taagcatatc
     1261 cacgactccg ccaaatccgg tctttttcgt aataaaacct agtgctacca ttcgttcatc
     1321 tagatttttt gctgtaatcg tcacaccagt aatgagcgag tgctgtaatg tttgggccag
     1381 ctcttccatc ccttcagcat tggatacgac ggaagctgtt ttgttaatag gttcttcgtt
     1441 tatttctttt ggttctttcc tctccacttt cactgtttga cgaaggacat ctagttcttg
     1501 caagagcgtt tcgtattgtt cttgggtcag catcacgcca gctacttttt cacgattaaa
     1561 tatatatacg ccagttcccg cgtctcgcgc ttgagcaaat acatccatcg gcgatcgttt
     1621 cacttctgtg atcgaagatg tgggaacttc taatttcttt aattccaatg gatttcctcc
     1681 tttactaatc gctttttatt atagcacaga ctgacttgtt ttgatctttt ttccaaaggt
     1741 tttatcggtt tttgcctaac cagtaattga tatcggtaag aagtctttcg ataccaaatg
     1801 aaggatggta cagatacgtt ttttgatctt cgttatggtc tagtggaaaa aaatgatcga
     1861 tgatcactag atctgcatac cgaggcggct tatttcgagt acatacatgt atagagatcc
     1921 gttttcgatg tcttagcgtt ttgttcagta ccccagcaag tcttcttgct tcttggtgtt
     1981 catagcgaaa aaaaaagacg attttcactt caggagggtg gacatctaaa taccctcgtt
     2041 cctggagtgt tttcagtaaa agcatccccc actctactgc ggggtgtgca agtgcttgtt
     2101 ggatcgctag ccgaaattga tatagtttat ctttggaatt gggaaatttt tctaatgttt
     2161 cctgataata acgaacttct tctatcagcc ggtcatggat accaattacg taacgaagtc
     2221 attcttggta aagtactttt gtcagctttg atttgctttc gctctcaaat tcgctattca
     2281 gccaaaacag cgaatcaagc ttttcagtca caatcgtcaa tttccgatag tcttgtgtct
     2341 cttctatccg tttccaccgc ttttcagtaa tctggttaca gctcaagcgc aaaattgcta
     2401 gataattttt ttcttttatt ggcaaaatct gctcctctct aaatagcaat tcaggaaaca
     2461 attcaaagaa tagtgttcga ctgtctccta aaatctcgat ttctgccgga tcctttcttt
     2521 gcttcaataa ttggatgaac atctcagaaa aggactgctc tccatcatct gcaaaaaaat
     2581 gcggaaaatc tttcaaaaag caaaacagca gatatcttac ttttctttct gaaccaaaga
     2641 tctgtgcttt tttataagaa aaagaaaggt ggtactcgcc aaaccacttt ctcaatcgct
     2701 cttgcgtaga acgatcgtac ttctgctcgt aaggttcatt caatagcaga tttttcagta
     2761 aacaaaacgg gggtgattgg atcagaaaaa caaacaagag ataaggttcg ctatatcctt
     2821 gatcataaac taactgaacg gttttcttat gaagaatcag ctgaatggga cagtcgcttt
     2881 ccgccaaacg tttcagatgc cgatccactg ttttaacatc gattttcagt tcttcagcta
     2941 aatcagcttt tcgccagatc aaatctttca ttagattgat tagtgaaaat aaattctgtg
     3001 cattttttga taatagtttt tgccatctca tcgatcattt ctcacctgat ttctaaacat
     3061 attgtttgat caaaatgggt tcactcctaa aaagataaaa aactcccttt ctatttattt
     3121 aaatgcgcaa atcttcctca ttatttttta ttttactcaa tttaatcgta ttctcatttc
     3181 aaaacgaatg tactttaaaa aaacataata agatcacttt gcttgtagga tgtattccct
     3241 tccattacaa tgaaataaat agcgatttta tgagaaggtg atgtgaaaat ggaagaaaaa
     3301 atagaagaat ccaaacaaaa aatcgatcag ttgatataag aattagaaaa agcggtcatc
     3361 ggcaaacgtt caactatcca attgatgatc gtggccctat tagcaggtgg tcatgtctta
     3421 ttcgaagata ttcccggtgt aggtaaaacg ttactggtca aagcactagc aaaagctgta
     3481 cagggaacct tcagcagagt ccaatgtact cctgatctgc tgcctagtga tattcttggt
     3541 ttttccgtat acaattcaca atcaaaagag tttgaatttc gtccgggacc gatctttacc
     3601 acgatcttgt tagcagatga gatcaatcgt acgactcctc gtactcagtc agcactttta
     3661 gaagcaatgg ccgagaatca tgcaacgatc gacaacaata cataccctct agacaatcat
     3721 ttttttgtct tagctacgca aaatccaatc gagtacgaag gaacatatcc tttgccggaa
     3781 gcacagctcg atcgtttttt attccgacta caaatcggtt atccttcttt tgatgacgaa
     3841 cttttgctac ttttggataa attcgaaaaa gtgttggata acttaaatga agtattgaac
     3901 agttatgaaa tagaagaaat aaaaacaaat gtggcgaatg tctttgtcag tcccgaagtg
     3961 gcatcttatg ccttgcagtt agtgtcagca acaagaagtc atgctgccat ccagcttggc
     4021 atcagtccac gaggaagcct ttcctttatt caggcagcaa aagcttatgc tttaatccat
     4081 gggagaaatt acgtcacgcc caaagatttg caggatttag ttccttacgt gttttcccat
     4141 cgcctgattt tttacgatcg ttcattgaag gaagacgaaa agaaacaaat cattcatact
     4201 cttgttgcac aaattcctat tcctgtgagg tagattgagg tagacaatgg aaaaaatcaa
     4261 agattatttc attaattttg tgttatttct ggtatatttc atcattgtgc tttttgctct
     4321 tgtattcaac aattctttag gctggttctt gttggccttt tttactcttt atgtatcatg
     4381 gagcttgatt tcattaagca gctttctaaa gaaactttcg gttacttgta cattgcagcc
     4441 actcgtttat cgcaaaaaaa gtatgcaggt tattttttcc atagcaaaaa agagaacttt
     4501 ttctttacct ctccctcgtt tacaaatcgg cttcccagca atctttgcag aaaaaaacaa
     4561 gagattttga ttcttacaaa taaaccgcaa gaagtccaat tgctttggca gccaaaagaa
     4621 agaggatgcc atgaaacatt aactgtcatt tttacagcct atgatagtct aggacttttc
     4681 agaaaaagtg caaaaagaga gatctctttt cctgtgactg ttctgcctgc tttttgtaag
     4741 attcaagcag aaaaattaca gagagttctg gaaaaaaaac agcagctgaa cgcgtaccaa
     4801 agaggtcttg attttcggga acatcgcgct tatcgtccag gtgattcttt caaccgaatc
     4861 gattggaaat tgtctgctca tactcaagag tggttatacc gtgaatacga ttatcaagaa
     4921 gaagaatgtt ctcctctttt ttgcttttgg ggttcgccca gtccaaaatt tgaacctctg
     4981 ctagacttgt atttttcttt atggcatttg agaaaagaaa agcagccgga acttctgata
     5041 ttaggcaacc gcgcctttca tggcaaagac cccggtcata cctattttgc ttctttggaa
     5101 gctggcgatg agaaaacttt tttcgcacac ttgaaaaaat atgcaaaaaa acaaatcgtc
     5161 ctctttgttc ctgagaattc tcctgaagtc tcagaagcta ttgaaacatt gtcaaaagat
     5221 cgaacggttt atcttgttta tttcgtagaa aaacaactca tggtccaaga aaaagacaag
     5281 atatgttcat tgccaggagg tgaatggatt gacgattaaa cgggaaaaat ggctgcgtgg
     5341 cgtttactcc tttgtgatac taagtgtagg tgctccgata tttgtagtag ctaatcaatt
     5401 gcaaaacagc taccttctta tcctaactat tggtgtccta tgccttattg tctgctgtat
     5461 tcctaaaaaa tgggtacgtt tgctgctttc tttgccagta atgataggtt gtttgttttt
     5521 atattttcct tcgaagacat tttccatatt atggatctta cagttttttt cgtcagttac
     5581 agaggaattc ttccatctat cccaaggtaa actttattat ttgccagaaa agacagcttt
     5641 ttttctcata atgttgctga tctatttatt tattacattg accgtggatt acgactattg
     5701 gtacgcaccc tttctttctt tgatggctta cttcatgatg cttaccgttt ttcggaaaaa
     5761 agatttactg tacgaaatga ttgcggtagt aactgttttg ttcgtgtatc tggcagcaag
     5821 gcaatttttc tccatccggt tgttgtcgag aaacactcga ttccagtcat tgactacagt
     5881 tctgcttatt tgtttcttaa cttttagcgc tatcttgcct ttatatcttc cgaaagtaca
     5941 ccaatctctc gaggaaacga gtgaaccgat ccgagaatat cttaatgatg aagggcttta
     6001 tgacacactc catgagtatc aattaaccgg aagtgcaaga acaggcttca gtgagaatga
     6061 tgaacagctt ggtggacctt tatatgataa tggcgaagtt gtttttacag cgaaccaaaa
     6121 aggaaatggc tattggaaga tcgaaaataa aaatcattac accggttctg gatgaataga
     6181 agatcaggac gcacccatcc aaccaatcca agaattccct gttgacatca cgagctacca
     6241 aaccgttata gaagacaaag aaaacattac attgacccta aaaaaacaag ctttcttacc
     6301 ttatccttat ggaaatacta ccttgactga tttttcatta gctagtggac aaacgcttta
     6361 ctatttgcct gaaagccagc gattcattcc tgtcccgaat gaatcgacac gttctgcaac
     6421 tttacaaaca gaaaggttag tttttacgag agaagaatta aaaagcagtc agttaaaagc
     6481 tgatgattta gaaaatcagc agacaaatct tcaattgcca aaaagtttgc ctaaacgtat
     6541 tgaggacttg gcggtcgaat tgaccaaaaa tgaagcaact ttaattcgta aagtcgaagc
     6601 tgtctaacag tatttaaaaa caagcggaaa tttccgctat tccaaaacgg ataccgggca
     6661 tactccaaaa gaacacgatt atgtggatta tttcctcttt gattcaaaag tcggctattg
     6721 tgacaacttt tcaacttcta tggtcgtcct tcttcgaaca cttggtatcc cagctcgctg
     6781 gacaaaaggt tttacaaatg ggctcagaac aggcacagat aatcaaggga atgaggaata
     6841 cagcattctc aatagtcatg ctcattcttg gccagaggta tactttcctg gatttggctg
     6901 gcttccattt gaaccaaccc cttcatttgc caatccaatg ggttcacaac cagttgctga
     6961 aacaaccgaa accgtccagc ctgctatcga acaaccaaat gaaagcgaaa atatggcaga
     7021 aactatttcc agtgagagat ctgaggtcat tccatcagaa gaaacaacac tcacaccagc
     7081 ttataaaatc gtcttattca gccttggagt gtgtttatcc gtcttgttgt tctttctatt
     7141 gttattcaga aaatctctgc gctggacaag ttatcttatc tatcttcatt tttttgcttc
     7201 tactaatacg attgcatatc aaaaacttct taaccctttg gaaacattgg taccgcgcaa
     7261 acccgcagaa tctttgcagg aatatagcct gcgaatagaa caagaattca agctagatct
     7321 gcgtttcatt cgattaacta ctcaatatga agcagaaata tatggacgac aagcagatcc
     7381 ggtaaaattc gataaaaaaa cctatttaga aataacgcat ataataagaa aaacggtata
     7441 caaaaaaatt ctgacaaaag ggagccgctt caaaaaataa gataaaattt ctggagaatc
     7501 tacttctcga atgccgagaa ccagctgatt gagtatcgat tactcgaaaa aaaggttgtg
     7561 acacgttttt tgtcacaacc t
//
LOCUS       DAIGQM010000090         7497 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.094, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000090 DAIGQM010000000
VERSION     DAIGQM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.094"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..115)
                     /locus_tag="NOA48_002475"
     CDS             complement(<1..115)
                     /locus_tag="NOA48_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0790703.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="NOA48_002476"
     CDS             246..698
                     /locus_tag="NOA48_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790704.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="NOA48_002477"
     CDS             712..1401
                     /locus_tag="NOA48_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790705.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPILPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="NOA48_002478"
     CDS             1526..3877
                     /locus_tag="NOA48_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HCI0790706.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="NOA48_002479"
     CDS             3957..4352
                     /locus_tag="NOA48_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790707.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="NOA48_002480"
     CDS             4677..5294
                     /locus_tag="NOA48_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0790708.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="NOA48_002481"
     CDS             5335..5634
                     /locus_tag="NOA48_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCI0790709.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="NOA48_002482"
     CDS             5668..5835
                     /locus_tag="NOA48_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0790710.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6485)
                     /locus_tag="NOA48_002483"
     CDS             complement(5880..6485)
                     /locus_tag="NOA48_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0790711.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6745..7425)
                     /locus_tag="NOA48_002484"
     CDS             complement(6745..7425)
                     /locus_tag="NOA48_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HCI0790712.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2527 a         1101 c         1444 g         2425 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattttgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttccatc
     6421 attgccaatt gtcgatccaa attttgatct tgtgaagata ctcgaatata gccaattttt
     6481 cccataaaaa actccttttt aaaagtgata taatttacat gtaaaattta cttgtagttt
     6541 tactgctatc atagcatttt taaaaataaa ttttatgtag acttaaaatt tacttcatgg
     6601 agggtttaaa tggatgaaat caaaagtaac aaaaaagcat ttggcattta tttaggagaa
     6661 cctagtacag aacaattaaa ccaatttttt ggttctgttg cgaagtttga aaatcaaacg
     6721 cgccctctct gaactccaaa tatcttaggc tgttattccc attaatacct tgatttcagt
     6781 agacaccgaa aagccgaaga gcgttccatt tcttcggttc tttttatata ttcctcgaat
     6841 ggtctccatg cccttaatcg tggaagaggc tgtacggaga ctttgataaa atttatttcg
     6901 tcgtttaata ggtcgatggt cttgttctat taaattgtta agatacttca cagttcggtg
     6961 ctctgtctta gtatataaac ccacactctg taactttcta aaggcggagc caagagaagg
     7021 tgctttatcg gtcacaattg ctttcggctc accaaactgt ttatggagtc gttttaagaa
     7081 agcataggct gcttgcgtat cccgtttctt tcgtaaccag atatctaagg ttaagccgtc
     7141 cgcatcaatt gcacgataaa gataatgcca acgtccctta attttgatat aggtttcgtc
     7201 cattttccat gaatagaagg attgtctatt tttcttcttc caaagataat agaggacttt
     7261 gctgtactct tgcacccaac gataaatcgt agtatgacaa acatttattc cacgatcata
     7321 taacaattcc tgaacttcac gatagcttag attgtaacgc aggtagtaac caacagcgac
     7381 aataatgacg tcttttttga attgtttgcc tttaaaatga ttcattactc tgtcctctct
     7441 gtcttttttc tcaattttac actaaaatag attttttgga aaactttgca acagaac
//
LOCUS       DAIGQM010000091         7337 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.095, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000091 DAIGQM010000000
VERSION     DAIGQM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.095"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(482..907)
                     /locus_tag="NOA48_002485"
     CDS             complement(482..907)
                     /locus_tag="NOA48_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790713.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1281..2252
                     /locus_tag="NOA48_002486"
     CDS             1281..2252
                     /locus_tag="NOA48_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790714.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2284..3681
                     /locus_tag="NOA48_002487"
     CDS             2284..3681
                     /locus_tag="NOA48_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0790715.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3840..4463
                     /locus_tag="NOA48_002488"
     CDS             3840..4463
                     /locus_tag="NOA48_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790716.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            5212..7305
                     /locus_tag="NOA48_002489"
     CDS             5212..7305
                     /locus_tag="NOA48_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0790717.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         2503 a         1230 c         1489 g         2115 t
ORIGIN      
        1 aaaaccaaac gacgggaaag aaaaattact acgtgatgta gaataagcct ttctatcgtt
       61 tggttatttt atattcaaat atttgaaata aataaatctt tactctttga tttgtaaact
      121 gaaatgatcc actgtttgtt ttactgatga agcttgatca aaggaagaag ctgagtttga
      181 agttcataaa aatcagccat agtgagtttt gcttggattt gtttatcttc ttctactttt
      241 tacataattt tgaacaggat aagattcaaa tgttttaaat gaatctttga ctagtttgtg
      301 acagttgtcg catatgctca agcttccttg gtcattaaat tctgtatgga tatttttgtt
      361 gttattacat gtacaataat caggactatc gatcatccat ttcgtctcct ttacaatcat
      421 cttgcttctt tactatagca gaaaagaagg ggagaaacaa aagaagatcc aacagacggc
      481 actatagact gtagatgttg ccatcctcat ccttcaaacg gtaattaccg atttttgtaa
      541 atatgactgt tgtttctttt ttattttctt ttcctgaaat aatatattcg tcatctttgg
      601 tagtgatctt gatatctgtc agcactgttt tttcttcaga tgattcagaa gaatcagttc
      661 cttgtgtctg atacgtgcgt gtccattcca tttttttatc tgtaaatgtc aactgtcccg
      721 cggataaatc catatcttta cgtactttta gcgtatatac actgttggtg gtatctgctt
      781 tttccgcttt taagacagaa gaatcggttg tttcgtccga ggattggtca gagccgccaa
      841 acaaatcaca gccagtcaat gtcaaaagtc ccgcagacaa aataaatagt acgattaatt
      901 tcttcaaaat acttccccca tttgatagga taaagaaatt ataccattgg aatgtaaaac
      961 ttcaaacgga tggaagagaa aaacgcacaa aacacccaca aatagagtaa attttagaat
     1021 aaaattttaa aaaggcaaaa aatccgccac tttcagaaag cgttttaaaa aagtgttgca
     1081 atcttttaaa aaaatgctat attaaaaatg aaccggttca aatacttgtt taagtataat
     1141 taatagtgag aggaagttgc tctactgaag actttagtta tatggatatt gatgacaagc
     1201 aacactatgc aaagaatgcg gtcatcataa tcgaacaaca agaaagagaa atcaaatgta
     1261 actggcagga gtgagaatgt atggcatcga tccgtgatgt ggctaagatg gctggtgttt
     1321 cagtgggaac agtttcccgt tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa
     1381 aaatagcaga agcgatttca gcgttggact ataaagaaaa catcattgct aaagggttga
     1441 agaataatcg aagcttctct attggacttt tgataaacgg gatttccagc cgttttgggt
     1501 cggaagttgt ctcagggatc gaaagagtag ctgaagaaaa tgggtatagc ttattattaa
     1561 gcgggtttgc cgatcagcca gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg
     1621 tgatcgatgg gctgattgtc ttcttatccg aagaagagtg gtctggattt gaaatgctca
     1681 caaaaatgag tattccagtt atcgcattga attgtccaga aggaccagca ggtattgata
     1741 caatattagt gaatgatcga gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag
     1801 gacataaaaa aatcggattt attgctgcca ctcaaacaga ctacgtagca agagaacgtt
     1861 tagcaggagc caaagaagcg gtccaaaatg atccatcgat ccaattagag gtctttacag
     1921 gagactattc tagaaaaagc ggctattacg gggcaaaagc attattagaa aaaggggcaa
     1981 ctgctatttt tgtcagcaat tacaatatgt cgattggtgc catcgaatgt ttcaatcaag
     2041 aaggtgtcag aatcgggaag gatattgcgt tcagtcacta tgattattta gataaaaacg
     2101 atctgagtat ccttccgaaa atcacgatca cgccaccaac agataaaatc ggggaacgag
     2161 cagcagaaca gctgttaaaa cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg
     2221 tgatggaaaa tatcatacat ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct
     2281 ttgatgaaaa aatatcaatt tccagcaaat ttttggtggg gttctgcagc aagtggccca
     2341 caaacagaag gaaggatttc aggcgatgga aaaggagaga acatttttga ttattggtac
     2401 aaaaaagaac cgcaaaagtt ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat
     2461 acgaagtatc aagaggatgt acagttgatg aaacagactg ggcataattc atttcgaaca
     2521 tctatccaat ggagccgttt gatacctgat gaatctggaa caatcaacga agaagccgtt
     2581 cgtttctatc atcgttattt tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat
     2641 ctgtatcatt tcgatatgcc gatgtatctg caagaaaaag gcggatggtt gaaccgagaa
     2701 acggttgaag cctatgaaaa atatgccaaa agttgttttg aattgtttgg ttcgaaagta
     2761 aaaaaatggt ttactcataa tgaaccaatc gttccagtcg aagcaggtta tttatatcga
     2821 tggcattatc cagaagagtc agatatgaaa aaagcgatcc aagttggcta tcatgaagcg
     2881 ttggcttcag cgttagccat caaatcttac catgaaatgg agcaaggtgg tgttattggt
     2941 atcatcttga atctgacacc aagctatcca agagacgaat caaaccctga agatgttaaa
     3001 gcagcgcaaa tagcagatgc gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc
     3061 gagtttccaa gtgaattgat tgagatagta aaagaacttg atctcatgcc tgtgatccat
     3121 gcagaggatt tgacggttat caaagaaaat acagtagatc ttttaggtat caattattac
     3181 cagccacgcc gggtaaaagc aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct
     3241 gaggattatt tcgacaatta tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg
     3301 gagatctatg aacaaggaat ctatgatatt ttgatcaatg tacgagatca ttatggaaat
     3361 atcgactgct ttatttctga aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa
     3421 gaagatggca tgatccacga tgattatcgg atcgaatttg tccaatctca tctgaaatat
     3481 gtccatcaag ccattcaaga aggtgccaat tgtttaggct atcatatgtg gacatgtatg
     3541 gataactggt cgtggaccaa tgcatataag aatcgatatg gctttatttc agtagactta
     3601 gcacaagatg gaaaaagaac aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat
     3661 aaaaacggat ttgaggctta agaaagaata gttgagagca aatgcgtgaa attctccatt
     3721 cttaccattt tgtgaaaaag aagttcaatt atttacgatc tttttcaact tttttgtctt
     3781 tctatttcat tttttgtata taatagaata gtcaaaatta aataggagtg gaggaaagca
     3841 tgaggaaaaa aagaccgttt cttctctttt ggttattcgg ttttttctta ctgcttattt
     3901 tatccgcagc attttcagga aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa
     3961 tcgtagcaag caaagaatca gtagataatt tcaaaaaaga attctcaact tattggtggg
     4021 cggagtataa aataactgcc aattacgaaa aaggcgaatt ggacatttat ttgccaaaag
     4081 gaaaagaaga aaatcaattt attaatatcg atgacgtact tagtgcgatt tctctcagac
     4141 aatatcaatt taaagacaag catttgaccg ttttgctttt gactcatgat ggcgacaaag
     4201 tagcccgttt gaaaaatgga aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag
     4261 tggtcgccga tcgtttagcg gaatggaaaa agacaaatga acaagtcaag aaaacaactg
     4321 tctcttctca aaaaaacgag tcgacaggaa caagtccttc agattctggc agtggacaaa
     4381 cgataacggg aagtgaagaa aatcaagcct caattattac gaatgagtca tcacaaggac
     4441 aatatcaatc ctatggacaa tgaaaaacag aggttgtgaa atcagcgttt tgacctgagt
     4501 attagagaaa caaacggcaa aatagttcct catattttgc cgttttttga gctaataccg
     4561 aaggtcagct gattgaacac cgtgtatcaa gaggtcttga gcctgccgtt taactctgag
     4621 ccacaaggag caatttcaaa aaatagctcc ttatattttt cgtttggttg ggcttattac
     4681 cgcagatgca agcttttgaa caccgtttac caagaggttg taaaattagc gtcctgacat
     4741 aatctaatac cgagggtcag ctgattgaac accgtgtatc aagaggtctt gagcctgccg
     4801 tttaactctg agccacaagg aacaatttca aaaaacagct tctcatgttt tataaatatt
     4861 gtgacttgtg gccgaggagt tggcaggaga acaccgttta aggaagaagt tgtgaaaaag
     4921 ctgtcctgca tcaagaaata aggagctgcg acaagaattt tgtcacagcc tctttttttg
     4981 tacgaatacc gagaaactgg cttttgaata ccgtggagtg aagcggtcac cacaagactt
     5041 ttatctcttc attagtttaa tcgcttacat cgcagcggtt ttatgctgtg aaaagtggac
     5101 ggaataatct ttagaaagaa taaaaaaatc ttaagataac aactttttta ggaaattttc
     5161 atttttcagg agcaaaataa gaaaaaatgt gaatagagag aagtgatata cgtgacacaa
     5221 cttaaaaaat tgtgccaaaa tcgtttagca atcgttttga cagctgtttt ctttttctgg
     5281 ctgaagacga tcattgccta ctatgcagat ttttcattag gtgtggaagg tacgatccag
     5341 tactttatct tgtggatcaa cccaattgcg actaccttat tgttttttgg cctttctttg
     5401 tatattaaaa agccaaagcc agcgttagct attcttttga tcattgatat tttaaatacg
     5461 cttttgttgt acttgaatat tattttttat cgggaattca cagatttcat tacagtcaaa
     5521 tctgtattag gcttttcgaa agtgtcgcaa ggattgtcag gaagctcctt ttctttgatg
     5581 aagccccatg atgtcatcta ctggctggat atcgctgtgt tcattgggct actggtttgg
     5641 ttgaaggtca agaaaatacc tatcaaaagc aaccctgtcg gcaaaccgat ggctatcgct
     5701 gttacctgtc tttcagggct tattttttca ggaaatctag cgctgagcga agccaaccgt
     5761 ccacaattgc tgcagcgaac atttgaccgt tcatatattg tcaaatatct aggaatcgat
     5821 gcgtatacta tttatgacgg aatcaaaaca ggaatgacta gcagtgttcg cgcgcatgca
     5881 agcagtaatg ggattgatga agttttagat tatacaaaga aacattatgc agagccaaat
     5941 cccgaaacat ttgggatcgc taaagggaaa aatgtgatcg ttctccattt agaaagtttc
     6001 cagcagtttt tgattaatat gaaggtagac ggacaagaag tcacaccgtt tttaaatagt
     6061 attttccaga atcaagcaac gatcagcttt gacaatttct ttcatgaagt aggacaggga
     6121 aagacaagtg atgctgaaaa tatgttggaa actggcacat ttggtttacc tcaaggctca
     6181 ttattcacag aacttgggtc agacaatgtc tttcaagccg caccagcgat ccttggacaa
     6241 aagcaaggct atacaagcgc tgttttccat gggaatgtag ctagtttttg gaatagagat
     6301 catgtatata aaaacttagg ttatgacaat ttctttgatc gatcttattt tgatgaatcc
     6361 gacgaaacgt taggttatgg gatattagat aaagatttat tcagagaatc tgcccaatat
     6421 cttgagcatc tacaacagcc gttttacacg aaatttcttt ccgtaaccaa ccacacgcct
     6481 tattatacgg atgacaagaa tttcgacttt ccatctttga atactggcaa tagcacagta
     6541 gataattatg ttcgaacggc acattatctg gatcaatcat tggaacaatt ttttacgtat
     6601 ttgaaaaaat ctggtattta ccaaaattca atctttgtga tttacgggga tcattttggg
     6661 atctcgaata cagataataa agatttagca agcgctcttg gtaaagatcc agatacatgg
     6721 gatgaatttg acaacgcaca gatgcaacga gtgccattga tgatccatat gcctggttat
     6781 actaaaggga cagtcaatca tgaatacggt ggagaaatcg atgttttgcc gacattacta
     6841 catctattgg gaatcgatga taaagattat cttcattttg gtacagactt attatcttct
     6901 cagcatgatc aagtagttgc ttttcgaaat gggaactttg tgacacccaa atacaccgtc
     6961 ctaggaggaa aagcttacaa taatcagaca ggagaaatca tcgatacgaa agcagcagga
     7021 atcgatgagg aaatctccaa agatcaggaa aaagtcaaga ctgcgttaag tctttcagat
     7081 aagctgaatc aggaaaatct cttgcggttt tatgtgccaa acggatttga gacgattgat
     7141 ccgaaaaaat atgactataa aaatgaagcg gaacgtaatg aagcaatcga aaagcaaaaa
     7201 ggcgaacatt cgacaagtgt cttttcaaaa aatggtaata aaacaacaac caacttatat
     7261 ccagtaacaa gaacagacgt tgaacagcaa aaaaataatc aataaacaat caaaccaacc
     7321 ttcagtagtt agacaac
//
LOCUS       DAIGQM010000092         7189 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.096, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000092 DAIGQM010000000
VERSION     DAIGQM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.096"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(31..1437)
                     /gene="lpdA"
                     /locus_tag="NOA48_002490"
     CDS             complement(31..1437)
                     /gene="lpdA"
                     /locus_tag="NOA48_002490"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCI0790718.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            complement(1445..3088)
                     /locus_tag="NOA48_002491"
     CDS             complement(1445..3088)
                     /locus_tag="NOA48_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCI0790719.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            complement(3113..4090)
                     /locus_tag="NOA48_002492"
     CDS             complement(3113..4090)
                     /locus_tag="NOA48_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCI0790720.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(4093..5202)
                     /gene="pdhA"
                     /locus_tag="NOA48_002493"
     CDS             complement(4093..5202)
                     /gene="pdhA"
                     /locus_tag="NOA48_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCI0790721.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            complement(5663..7087)
                     /locus_tag="NOA48_002494"
     CDS             complement(5663..7087)
                     /locus_tag="NOA48_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0790722.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT         1855 a         1612 c         1297 g         2425 t
ORIGIN      
        1 ttcagttgcg tttcgcctgt attattcaaa tcaaatatgg attggtaaac ctaatgctaa
       61 ttccgaagca tccatgacga tttcgccaag agatggatga ggatgaatcg tcaaggcgat
      121 atcttcagca ttcattcctg attcgattgc taaagctaat tcagagacca tatcacttgc
      181 gccgactcca ccgatttgcg cgccaataag cacgttatct tcgatcgtcg taactagacg
      241 gatgaatcct tctgttttac caagcgataa tgcccgaccg ttccctgaaa atgggaattt
      301 atatgctttt gcttcgatac cagcatcttt tgcttctttg atcgtcatac ctacagaagc
      361 caattcagga tcagtgaagg ctactgccgg cattgcttta taatctacag ctactttttt
      421 gccagagatt gcttcagcag cgatttttgc ttcataactg gctttgtgtg ctaatgccgc
      481 ccctggaacg atatcaccga tggcatagat gttaggtacg ttcgtacgtc cttgtttatc
      541 caccgtgatc aatcctcgtt ctcctacttc gacacccgct tgttctaagc ccatatcatc
      601 tgtattcgga cgacgaccta cagtgaccat cacataatca gcagtaacgg attcttcttt
      661 cccgtccact gcatatttca ctgtcacgct gtcaccgtta tcgactgctt ctttcgccat
      721 tgcattcgtt acgactgtta cgcctttttt cttgaaatca tcttctacta attttactag
      781 atctttttcg taagttggta aaatttgtgg tgagccttca agaatcgtta cttctgctcc
      841 taagtttgcg tacgctccgc ccaattcggc accaatcaca ccgccaccga tgatcacaaa
      901 tttcttaggt acttctttca atgctaatcc gccagtagaa tctaacacac gtcctccgaa
      961 tttaaatcct ggaatctcga ttggacggga acctgttgcg atgattgcgt tattgaacga
     1021 ataagtttga gctgaatctg gatgaatgac gcgtagtgtg tgatcatcta cgaagaacgc
     1081 ttctccttcg attgtttcaa ccttatgttt ttttaatagg aaaccaacac cagaagtcaa
     1141 cgtatggaca actttgtttt ctttccattc ttgtgttttt gcaaaatcta gtttgacgtt
     1201 ttcactagtt actccaaaca tttcagaatc tagtgactct tgataatggt gtcctgcagc
     1261 tatcagtgct tttgaaggaa tacagccgac attcaaacaa acaccgccaa tatactctct
     1321 ttcaatgatt gctacttttt gtcccatttc agcagcgcgg atggcagcta catagccacc
     1381 aggtcccgca ccaattacaa ctgtatctaa ttctacagca aaatctccaa ctaccatttg
     1441 tttatcatcc ttccatcatt aatagctctg gatcagctaa aagacgtttg atattattca
     1501 ttgcttgttg cgcagttgct ccatctacga tacggtgatc gaaacttaat gacagtttca
     1561 tcacacgacc gacaacgatt tcgccttcag catttacgat tggttgttgt gcaatcgttc
     1621 ctacacctaa aatagctact tctggatagt tgatgactgg tgtaaaccaa ccgccaccta
     1681 cagatccgat attgctgatc gtaattgttc cattgcgcat atcttctgca gatagtttgc
     1741 cgtcatgagc taattttgct ttctcattga tttcgtctgc aatagcaaac attcctttgc
     1801 ggtctgcatc tttcacattt ggtacatata gtccgtgatc cgtatcagtt gcaataccga
     1861 tattgtagta atgtttataa acgatttctt ggtttgcatc gtcgatagat gcattcaata
     1921 ctgggtattt cttaacagtc gctgttaaag ctttcacgac atatggcaag aaagtaagtt
     1981 tcgtaccatt tgcagcagca acttctttaa atcgtttccg attatcccat agtttagaca
     2041 cttctacttc atcatgcaat gtcacgtgtg gagctgtatg cttactgttg accattgctt
     2101 tagcgatagc tttacgtgtt ggcgtcattg ctacacgttc ttccaagtct cctaagttgg
     2161 acttgaatgg ttttgctggt gcagctggtt tgctttctgc tgcaggagct gcttctttcg
     2221 gtgctgccgc ttctggcgct tctgatttcg ctggtgcact gcttggacca cctgccaaga
     2281 agttttcgat gtcctctttt gttactctgc caccttttcc agttgcagtt acttgtgaga
     2341 tatctacatc tttttcacgg gcaaattgac gaacagatgg catagccaat acacgtttat
     2401 ttggatcggc agcttcaacg acacttgctg aacctgatgt ttccactttt tcttttggtg
     2461 cttcagctga tggcgcacta gttgacggtg cactattgtg tccaggagca tcgatttcta
     2521 ctaatacatc cccaacattt gctacagtgc cttctggaac aatcacgttt ttaactgtcc
     2581 ctgtgacagg tgacggaatt tcttctactg atttgtcatt ttgaacttct agtaatgtat
     2641 catcttcatt gatcgtatct cctggtttga cgaaccattt gacgatttca ccttctgcga
     2701 ttccttcacc gatatccggt aacttaaatt ggaagactcc ttcgcttgac gatccagctg
     2761 attctgtatc aacagtgggt tcagcagccg gtttagctgg agtttgggat tctgcggcta
     2821 caccactgtc cccttcattg tcttcgtgtc ctggtgcatc gatttctact aatacatccc
     2881 caacatttgc tacggtacct tctggaacaa tcacattttt aaccgttcct gtaacaggtg
     2941 acgggatttc ttctactgat ttgtcatttt gaacttctag taatgtatca tcttcattga
     3001 tcgtatctcc tggtttgacg aaccatttga cgatttcacc ttctgcgatt ccttcaccga
     3061 tatccggcaa tttaaattga taagccatga ctttgtttcg tcccttcttt tcttaaaatt
     3121 ccgcgatttc ttttactttg tcttcgatat cttttgcatt tggcaaccag acattttctg
     3181 cttgtccaaa tgggaagact gtatcaggtg cagaaactcg tccgattggg gcttctaatg
     3241 aaaggatagc gcgttctgag atctcagaaa ctacttgcgc ggcaacgccc gcttgtcgtt
     3301 gtgcttcttg gacaacaact acgcgaccag ttttttccac ggattgaatg atcgtttcta
     3361 catctaatgg cgcaactgta cgaagatcaa tgatttcaac agatatattt tcttttgcaa
     3421 gattgtctgc tgctttgatt gcttcacgca ccattgctcc gtatgtgata atagatacat
     3481 ctgttccctc acgagtaact gctgctttat ccaaaggaac ttcgtaagct tcatccggca
     3541 cttcttctcg gaatgagcga tatagtttca tgtgttctag gaaaacaacc ggatcgttac
     3601 ttctaataga agaaatcaat agtccttttg catcataagg gttggaagga atcactactc
     3661 gaataccagg agactgagcg atcaaacctt ctaaattatc cgaatgcaat tctggtgtat
     3721 gaacaccgcc accaaatggc gaacgaattg tgatgggtag atttctagtg ccgctcattc
     3781 gatatcttgt acgagccatt tgagctacta cttcgtccat tgcttcgaaa ataaaaccaa
     3841 agaattggat ttcaggaact ggacgaaatc cttctaacgc aagaccgaaa ctcaatcctg
     3901 cgattccaga ttcagctaaa ggagtatcga atactcggtc ttctccgaac ttttcctgca
     3961 atccttcagt tgcccggaaa actcctccgt ttttcccaac atcttcacca aaaacaacga
     4021 cattctcgtc attttctagt tcaagtgcta aggcatctgt gattgcttgg atcattgttt
     4081 tttgtgccat gattatttcg actccttcgc ttcataaatt gcaatttgtt ctttgattga
     4141 ttgtggagat acttcgaaca tgtttttcaa gaaatctgaa accttttgtt ttggtacttt
     4201 gtcggcttca gcaatagctg ctttgatttc ttctttagtt gcttcgatga cttgttcttc
     4261 tttttcttca gaccaaagtc ctttttccgt caaatattta cggaagcgga tcaatggatc
     4321 ttttttctgc caatcgtcat ctgtgtcttt tgtacggtag cgggttggat cgtcaccaga
     4381 tagtgtatgt ggtccataac gataagtcag tgtttcgatt aggactggtc catttccact
     4441 gatcgcccat tcccgtgcca ttttagatac agtatatact gcaagcggat ccattccatc
     4501 gacttgaata ccaggaatcc cagctgcgac agctttttgt gcaagtgttt ttgctgcagt
     4561 ttgtttttca cgaggtgtag agatcgcata cccgttgttt tggatataaa atacggcatt
     4621 tgcatggtaa gcgccagcga aattgattgc ttcgtaaaaa tcaccttgtg atgaaccgcc
     4681 atcaccagta taagtgaaga cgacattttt cttgtttcgt ttcttcaaac ctaatgcaac
     4741 accggctgct tgtacatatt gtgcaccgat gataatttgt ggtggtagag ctttcaattc
     4801 ttccggataa gaattacctg cagcatgtcc tcgagaccat aaaaaagctt gagataaagg
     4861 taaaccatgt tttactagtt gaggtacatc ccgataacct ggaagaagaa catcttcttt
     4921 atcaaatgcg taagcactag ccagctgact tgcctcttgt ccagcagttg gtgcaaaaaa
     4981 gcctaggcgt ccttggcggt tcagcgctgt tgaacgttgg tctaatacac gagaccatac
     5041 catatgagtc attaattcaa cgagttcatc atcggataaa tcaggtacta aatctttgtt
     5101 aactacgttt ccatcttgat caagtgcttg atatactggg aaatctgcat tgacttcatc
     5161 tagcagtgct tggaagtcga tcggtgcttt tttgtttgcc atttgtcaca cattcctctc
     5221 tcatctataa gaaaatctct tcattctgcg attgaaacag tgaataaaac tgtatcacta
     5281 tttaaccgtc ttcattaata aattatcatg gatttatgag aaatacaagc taaaagcaca
     5341 aattttcacg atgaaaggaa attatgccaa tccgcatatt aacagcatta gtgaataaaa
     5401 tcacaataag gaaagcgttt tatatttcat ctgcattttt tctattttct aatcaaactt
     5461 acaaccatct gtttctattt aaaaacgttg gtgttataca gttttgttgc aaacatttat
     5521 tttatttaca catcgtgaac ggacgtacaa ataatggttt tttcttagtt tctttatatc
     5581 gtattctttt tccgaaaaaa aagaaacagc ttgaaattta aatccaagct gttatattct
     5641 ttaatctatt tactttgtga aattattctg ttaaccactt ttctagaatt ttcatctttg
     5701 aataaaacaa cggtatttgg ttttcatcca gcctactgta attgattctg attccattta
     5761 tatcttgccc aaaaagtaga cttggtgcaa ttccaagacc catatctact actttttctg
     5821 ctagttcggg gtctagtttt ttcccatccc aagtaatcca ggcatagtaa ccacctaaaa
     5881 ttgaatgaag cttgaaaaac gattgtgaat ctccccaagc gcttatcagt cggctttttt
     5941 ctttcaactt ttttcttaca tcttgcattt tcaaatcaat tgcttcatta aatacattag
     6001 ccactgtgat ttgtgtaagg atattcatcg aaaactccat catttcttgc gcttgagcta
     6061 gttgcgagat aaaagtctca ggtcctatca cccaaccgat tttcgttgtt tttcctaaaa
     6121 ccctagataa cgaaccgacg tataacacat tatccggatc aatcgttcgt ataggaagga
     6181 cttcttcttg gtttagaaat gaaagatccg taaatacatc gtcttcaata attggaagcc
     6241 gatactgtcg acacaattct actagctttt ctcgtcgttt ttgactcatc acttttcctg
     6301 tagggttttg aaaattcggg ttgataagca ctgctttcaa tttattttta tggatcgatt
     6361 ctttcagttt ttctaagtcg atcccttctt catccatcgg tatcccaaat aaacgcgttc
     6421 ctgaagcttt gaaaagaggt aatcggtaaa aaaaagaagg tgactctaca gctatcccct
     6481 ctccagctga aagaatcgtt tgtaaaatca aaaagattgc ttgctgaccg ccaccagtca
     6541 caagaagctg gttgggggaa aatgccaatt caaatttact ttccaaatac cgtttgattt
     6601 tgttacgtaa cggagtatag cctaaaagat ccatttcttt ttcttccgct aagatttctt
     6661 caagagaata agaaggaaac tcaaaattcg gcaaaagctc atctggcatc tcgctagcgt
     6721 ataaatcaag aaacgatgtt ttttggatct gctttgcttc tcttattttt tgctcatacc
     6781 agtccgtctg ctcataacga ggagagatca tttgccgcca atcgattctt ggaacagcga
     6841 atttccccca ttcagtctga ttaacaaacc atccgctgcc acgtttgctc gttagtaccc
     6901 caagctccct aagctcttcc aatgcatgga caacggtgga acgattcaca ccaaaaagtt
     6961 gccctagttt tcgttctgat tcaagttgac ttccaggatt gatccttccg ttttcgattt
     7021 ctctcataat ctgttccata atttgacgat aaatcggtcc ttgttttttc tctacttttt
     7081 cccacataag cttctctttt ctattgtcta ttttttcttt tgattttacc gaatttacga
     7141 gaaaaaagaa aaactttttt tgcaaaacat aagggactgt gacaaaaat
//
LOCUS       DAIGQM010000093         7162 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.097, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000093 DAIGQM010000000
VERSION     DAIGQM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.097"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            236..1627
                     /locus_tag="NOA48_002495"
     CDS             236..1627
                     /locus_tag="NOA48_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0790723.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
     gene            1665..2495
                     /locus_tag="NOA48_002496"
     CDS             1665..2495
                     /locus_tag="NOA48_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0790724.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            2467..3456
                     /locus_tag="NOA48_002497"
     CDS             2467..3456
                     /locus_tag="NOA48_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0790725.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            3570..4565
                     /locus_tag="NOA48_002498"
     CDS             3570..4565
                     /locus_tag="NOA48_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0790726.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            4569..5711
                     /locus_tag="NOA48_002499"
     CDS             4569..5711
                     /locus_tag="NOA48_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCI0790727.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQFYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSEK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNLMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELLERDIK"
     gene            5708..7135
                     /locus_tag="NOA48_002500"
     CDS             5708..7135
                     /locus_tag="NOA48_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI0790728.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
BASE COUNT         2558 a          932 c         1260 g         2412 t
ORIGIN      
        1 tatgaatatt gtaacttgtg aataaggaat tagcaggaga atactagttc agcataaagg
       61 aagtgatggg acttctgaga caactttctg ttatgcagaa atacacatat aaacagacaa
      121 taaacgcttt tccccgtttc ttttaatttc ctttacaatt tggttattca ctaggttttt
      181 aaactttgct atggtaagat gatagaggca ttattttatg gttaggagtg tatatatgaa
      241 taaaaatggg gagtggaatg cggcacgcag aatattcatt attcttatgg atgtacttgt
      301 attaaatgta tcgatctatc ttagtttttt gctgaaattc cagggagaag taccagtgag
      361 aaacttagaa acctttcagc attcagcaat ttttatttcc atcatcttta ttgcgttgaa
      421 tattttgtta ggagcttatg tattctataa ccgaatgatc agtgatattg tcttcattac
      481 tgttattgga caagtactaa tagcattggg gatcatggta gttacttttg ctggccgatg
      541 gtttgcattt ccgcgtggcg tcattttgat ctcgtttatc ctaggtacga tattacttag
      601 tgtttaccgg atagtcgttt acaaactgta cttaagagtc agtcgtgata agaaagtcct
      661 tatcgtgggt ttggagaaag atgtcgcacc agctatccaa aattttcaat ctaagaaaaa
      721 caataaacat aaggttgaag cagtggcaat cgataattat tacgaaaata caaaaaaatt
      781 gatcgatgat atggatatcg tctatttggc ttctaaaatc ccagaagatg aaaaaatcaa
      841 catttatcaa ttagtgacta aaaaagagaa gaaattattt ttaaatacga cttttgagaa
      901 tctgacaatg ataaatccga atattatgaa ttttgaagat gaaagcatca ttgaagcttc
      961 tgggttcaga atccaaccag aatacgaact attcaagcgt ctctttgata tcatcgtttc
     1021 gcttatttta ctgatcctcg cctcaccttt tatgctaatc acagcgattt tggtaaaaac
     1081 aacttcacct ggaccaatca tctataaaca agtacgtatt acgaaaaatc aaaaggaatt
     1141 ttcaatctat aaattccgtt ccatgagtgc gacagctgaa gcaaaatcag gaccagtctt
     1201 ggctaaaagt aacgatgcac gtgtgacacc agtaggtaaa tttatccgtg ctgtacgttt
     1261 tgacgaatta cctcaaatct ttaatgtatt gaaaggcgat atgtcgattg tcggtccaag
     1321 gccagaaaga ccatttttcg ttgatcagtt caatgaagaa aatccttatt attacttaag
     1381 acacaatgta cgtgcgggaa ttaccggata tgcacaagta tacggaaaat atgtatcaga
     1441 ttataacagt aaactacgtt ttgatttgtt gtatatcaaa aagtattcct tactattaga
     1501 tttgaagatt ttacttcaaa caatcaaaat cttatttgat aagatgtcct cacaaggact
     1561 agatgaagat gaaaatatca gttcattagc agaaagtgca tttccaaaag aaaaaacgta
     1621 tcgttagatt ggaaaaattt tgagcaaaga agtaggagag aacattggaa aataaaaata
     1681 taagtatact gctttctttg tatgataaag aaaagccgga atatttaaag gaagcattag
     1741 ctagtatctt tgagcaaacg gtgatgccgg cagaaatcgt attggtttat gatggcccta
     1801 taaatgagaa gcttcaggca gttgtcactt atttccagca aaaagttcct cacttgttta
     1861 cagttgtaaa attagaaaaa aatcaaggat tggggattgc tttagcaact ggattagaac
     1921 atactaaaaa tcgcttagtg gccagaatgg atacagatga catcatggaa ccacacagat
     1981 tggaaaaaca attagagatc ttccaagaat atccagaaat agcgattgtt gggagtaata
     2041 ttgaagaatt tactggcaca cttagcaatg ttatcggaag aaggattgta cctgagtata
     2101 atgatgaaat ccgtgtgttt tcgaaaagaa gaaacccttt taatcatatg acagtcatgt
     2161 ttgataaaaa tgctatttta gaagtgggaa actatcgccc attaattgga tttgaagatt
     2221 attatttgtg ggtaagacta ttgaaggcgg gatataaagg atataatatc caagagattc
     2281 tagtacatgc tagagcaggt gctgacatgt atgctagacg tggaggaagt aaatatcttt
     2341 taccaggaat taaaggccga tatcgcgtat ggaaagatgg tctaggatca ctaaaagatt
     2401 ttctgatagt tatttgcgga catcttgtaa ttagtttatt accgaataaa attaggggaa
     2461 aagtatatga atcaaaactt agaaaaacaa actaaacttt ctataatcat acctttttac
     2521 aatgcaaaga atactttaag aagagctgta gacagcgtct taacgcaagg ttatcccaat
     2581 attgaaatct tgttaattga tgatggatct acagatggta gtagtgacat tggtgacgaa
     2641 attgctaatc tagagagtaa agtagcatgt tatcacttgg aaaacgctgg tccatcagtt
     2701 gctaggaact atgggataaa agaagcaact ggaaatttgg taggattttt agatagtgac
     2761 gattattttt tacctgattg ttttaataat gttttgaaag actaccatag gaatcacccc
     2821 gatatcattg cttttggatt aagtaaagga aaaaatatag aaaatgcaaa tttatttgtt
     2881 cccgaaaaga agattggttg ttcaagtgaa gaagcaattg agcaaatgtt tagaagtaag
     2941 gcagtggact tttacgtatg gaataaattt tttaaaaggg aattattcaa tcatatagtt
     3001 tttccagaaa ataaattata tgaggatatg gttcctatgt atgaagcttt tagggcggct
     3061 agtaaaattg atattttgcc attttcaggt attttttatt atcaaaataa cgatagcatc
     3121 gtttatcagt cttttaattc aaaacagtat gataatattt tgcagagaaa aatattagtt
     3181 gatgaagtaa agaaagatta tcctcgactt attaatttgg ccaatgctcg gttagtagac
     3241 ggatatcttt caacagggtt taaaattact ggcaaaaatc aaaatcagaa agaaaaacaa
     3301 aaatattata atcagtctaa aagagaaata aaaagtatat attcaaaaat aagaagtaac
     3361 aatgagatat caattgctaa aaaattagct ttatttttat acttaattaa tcctaaaact
     3421 tattttattt tatataaaaa agttctaaaa aaataaagtt tttttcgata tgttattttt
     3481 tatgtttatt aacttcggaa gactaaaatt gttactggta atgatacatt tgtaaaaata
     3541 aaaaagatga tttttaggaa gtgaagagag tgcataaaat tagtgttata gtacccgcat
     3601 ataacgtaga aaactattta gaaaactgct tagaatctat ttccaatcag acacattcaa
     3661 atattgaaat aatagtagtc gatgatggtt ccccggatcg aagtggggaa attgcagaag
     3721 aatataaaaa gaaagatatg cgattaaaag tgatacatca agtgaatggt ggtttaagtg
     3781 cggctaggaa ttctggtctt gattctgcaa caggagattt tgtgtgcttt attgacagcg
     3841 atgattggat agaaccagac tatcttgagt tactatattt tggtacgcaa acttatggag
     3901 cagatatctc ggtgctaaaa ataaaaaaga tttcaagttt agaacaacta aaagaacata
     3961 caattgctga gagaaaatgg gaaatatttg atagagaaca agcaatgaaa aacttattta
     4021 taaataataa aattggctat tctgcaaata ataaattatt caatagaaat ttatttgata
     4081 atataagatt cccactgggt aaattaatgg aagataaggc tactacttat ttgttgatcg
     4141 atcattccga aaaagttgct gtcaattcat ctgctaaata tcactattac caaagcccta
     4201 aaagtatact gagaggaagc ttcaatccta gaatttttga ttcttttgaa gtccatgaag
     4261 atatactagt attcatagat aagttttatc cggaattatc aattaatgtt agaactcgct
     4321 atgtctatga agcaataagg atgatgatga caatgattaa aaataactat accaataaag
     4381 aagattattt acgttctata aatattttac aacgctttga aaaagaagtg aaaattgatc
     4441 ccgacttttc accaaaatta aaaaaattag taaagttttt attaataaat aaaaacttgc
     4501 cttactatat gtcaagtagt aagatagcaa gtaaattttt gattaagata gaatctgtga
     4561 ggtaagagat gaagaatata aaaaaatttt tttcaaggaa tattttcccg gtttttatta
     4621 aaatattacc tattcaaaaa aatttaattg tattttcaag ttttggcggg cgtaattatt
     4681 ctggaaatcc aagagttatt tcagagaaaa ttcatgaaaa aaaattgaat tacagaatta
     4741 tttggttaat caaaaaagaa gcgattataa ctgatttacc agattatatt aaaagaattg
     4801 attccgattc ttttttagct gccttttatt tgtatacagc taagtattgg atagacgata
     4861 gtcggaaaac gattaagtat gcaaaaagga aaaaacaatt ttattttcaa acatggcacg
     4921 gtacgccttt aaaaaaaatt gaatttgatg caaaagataa gttacctaaa cgttacctaa
     4981 gctatgcgaa aaaagatagt gagtcaatta catatttatt atctggtaat cgctatagtt
     5041 ctgagaagta tgtttcagca ttcaatatcg ttccttctaa aatattagaa gtaggaactc
     5101 ctagaaacga tgaattagcc tctagtaaag agcaagtgtt tgacttgaaa aagaaacaaa
     5161 tcaatgtctt atttgctcca acttttcgaa ataatattga ggacaacgga attacgcaac
     5221 tagaatggtt aggtgtggat aacttacgtg aattttttaa aaagcaacaa caagaattaa
     5281 atttaatgac taaatttcat cctaatgttc atagtaaatt agcaactgat tctaaaagta
     5341 tagaatatat gaaaaaacat caaattactt taattaatga tgggattcct cttgaaatgc
     5401 tttttgaaga gatagatgtt ttaatcacag attattcatc tatttttttc gattttgcgc
     5461 taacaaaaaa accaattatt ctttttaact atgatgaaaa agaatatagc ttagaaagag
     5521 gtttttatat acagttaagt gagttaccaa ttataagcgt acaagatagt tatggccttg
     5581 ttgatgtttt taaaaaccaa caagaaaagc ttttgaaaag ttctcaagag ttacttgatt
     5641 atattggaaa ttatgaaaca ggggcaagta cagaaaaggt tcttgagttg ttagagaggg
     5701 atataaagtg aaaaaaacag taaaagatat attttataat gcgatatatc aagtcttttt
     5761 gattgttttg cccttactta ctatacctat acttagtcgt agaataggtt caactggttt
     5821 agggatttat gggtatgttt tctcaatatc acaattttta atgactgtca ttgctgtggg
     5881 aatgaatcct tttcgtattc gaaatatcgc taaatcaagg aaagataaaa aagcactatc
     5941 tttacaattc tggaatattt actttcttca atttttaata ggcttgagtg tttcctttct
     6001 ctatatagcc tatatttatt tttttgatgt aaagtataaa aatttatact taattcaatt
     6061 gatatttatt gcagggctaa cattagatat ttcttggttt tttcaaggaa ttgaagaatt
     6121 ttcgaaagtg gttattagaa atacagttat caaattatca tcggtattgt taataatcct
     6181 ttttgtttca actaaagatg atttgtggat ttatgtgttc attacttcaa ttactaactt
     6241 tttaggaagt ttagttttct ggttgagtat ccacggaaaa gtaggtaaac cactctttaa
     6301 ctctaatgtt tttaaacagt tgtggaaacc agcttttatt attttgactc ctcagttgtt
     6361 tatgcaagtg tacacaactt tagacaaaac gatagttggg tattttgtgg atccaacagc
     6421 attatcttat tatgatcagt ctcaaaaaat tgctcgtatt atattggcag tcttaacatc
     6481 aattactatt gttatgttgc ctaaaatatc taaagcacag gcagagggaa aatcagaaaa
     6541 tattttagtt tacacaaaaa aatcttttga ttacacgatt attattgcat taattctttt
     6601 tagtgtggtg tttatcaata caaaagaatt tgttccatgg ttttttgggg agaatttcaa
     6661 accgatgaca ataaacatgc ttatttcttg tctaattata gttgttagtc caattggtgg
     6721 agtttttgct aaccaatttg caattgctat agaaaaagat aaggagtatg cttatccaat
     6781 gatcattggt gcgattgtaa gtattattgg aaatgtagct tttgtgccta cttatggcgc
     6841 tgtagcggct acaatcgtac tcgtggtagt agaattatta gtctttttct ttagagtatt
     6901 ttttgtacga aaagaaataa aaatatccta tttctttggg aagaacgttg tcttattttt
     6961 tatagtcaat cttactttga ctacttcggc ctattacttt cttccacaat tattctcttc
     7021 ttcattttta gatatggcaa ttaaatcaat aatgattttc attatttatc ttccgtttgt
     7081 ttattttctt tttccagata tacgaaatga agtaagaaag attattcgaa aataaaataa
     7141 tgttgtaaaa aagtagttct tt
//
LOCUS       DAIGQM010000094         7022 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.098, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000094 DAIGQM010000000
VERSION     DAIGQM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.098"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..813
                     /locus_tag="NOA48_002501"
     CDS             <1..813
                     /locus_tag="NOA48_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI0790729.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="NOA48_002502"
     CDS             807..1229
                     /locus_tag="NOA48_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790730.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            1531..1911
                     /locus_tag="NOA48_002503"
     CDS             1531..1911
                     /locus_tag="NOA48_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI0790731.1"
                     /translation="MSEQNQNLASNYSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            1893..2807
                     /locus_tag="NOA48_002504"
     CDS             1893..2807
                     /locus_tag="NOA48_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0790732.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3047..3736
                     /locus_tag="NOA48_002505"
     CDS             3047..3736
                     /locus_tag="NOA48_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790733.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GFIFYLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3857..3943)
                     /locus_tag="NOA48_002506"
     CDS             complement(3857..3943)
                     /locus_tag="NOA48_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI0790734.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            4580..5524
                     /locus_tag="NOA48_002507"
     CDS             4580..5524
                     /locus_tag="NOA48_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI0790735.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            5545..6081
                     /locus_tag="NOA48_002508"
     CDS             5545..6081
                     /locus_tag="NOA48_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0790736.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTPILSEET
                     ESIEKHTKKKQKWWQLWK"
     gene            6097..6267
                     /locus_tag="NOA48_002509"
     CDS             6097..6267
                     /locus_tag="NOA48_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790737.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            6681..>7022
                     /locus_tag="NOA48_002510"
     CDS             6681..>7022
                     /locus_tag="NOA48_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI0790738.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2652 a         1212 c         1238 g         1920 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatctcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcgatta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acatgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacggaggca tttggctagc aaatatagag cttgccaaac
     1441 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
     1501 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
     1561 aattattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
     1621 gaatccgaat ttgcaaagct gaagcaatcg gctgaagctt tgcaaatgag tgtgccggct
     1681 ttcgtgaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
     1741 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
     1801 tggtgcaata cacaccaaca tgacgttgct tctggtgacg ctcaacgttt atccgaaaac
     1861 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac aattaaggta agccgaacca
     1921 cttcttgtag tcgtgcaatt aattatgcag aaccacgagc aaccattaaa acaggaataa
     1981 actgtgacgt cgattatgcc aaaagtgaaa tgaaacaaat tcgcatgctg tatggaaaag
     2041 acgaccgtgt acaggcacac ttattgattc aatcttttcg accaggagaa attaccgctg
     2101 aaaaagctaa tcaactaggg gcagagtatg caaaaaaaat agcccccgat caccaaatag
     2161 ctatttacac acatacagac aaagaccata ttcataatca cattgtcatt aactccgtta
     2221 atctggagac tggaaaaaaa tttcaagctc atggtcaagc atttctaaac aaatgttatg
     2281 acctaaatga cgagatttgt cttgcacata acttaccaat cactgagcga ggaaagaagc
     2341 cagaaaaacg aaccatgtct gaaataaaat taaaagaaaa aaatgaacct gtttggaaag
     2401 acgaaattcg gattgcgatc gatcaaacaa tgaaaaacaa aaaaaccaga acctatgacc
     2461 aattttgtaa ttccctcaaa acattgggga ttcattgctt caatcgcggg aaaaatttca
     2521 cttacgaatt gatccacaaa aagaaaaaag tacgatccaa cagactagga aaggactacg
     2581 aaaaggagac gattttacat gagctggaca gacgagaacg aacctataac caacagcgaa
     2641 ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcagaagaa gtacgaagag
     2701 aacaacgaac tcttacgcct gaacaaccgg aaattagacc ggctcgaaga aaccatgaac
     2761 aacacgttga aagaggaaca gaccaccaac aagaattatc gctctaaaac gttaaaagac
     2821 atagaaaacg aaataaagaa acaacgtgct tttctcgttc cttatacgca agaaaggata
     2881 caaactacga ttgatttaca agttaaaaaa ctccatcaag agctattaga ccagcgaaat
     2941 aaggaacaga aaaaggtgct tattcaacga tcattggatt ttcttgcccc cttatgttgc
     3001 ttagtcctga cactgttcgc attttggtta gtatggggag gctaaaatgg cattttattt
     3061 accctatcta ctcatttttg ttagtatttc aggaagtatt tggctcatct ataaaatttt
     3121 tcaaacaaga tattcattaa aaggctctaa aattcgattt aagcgatttt tctttcttgg
     3181 ctttatattt tacttgataa tcgtttcaag cggcttattc ggcgttttag agggaaataa
     3241 gcgcgtttct agaagtattt tattaggaaa tgtcactcaa aagtatgaat cagcgcgtga
     3301 taaaaagaaa aaagagcaag cattagcaca aaaaatggaa gagtttacca cttgttatga
     3361 ggaaatgaac gatatttttg tgaatcaaga aaaacgtttg acggataaaa atatggaaac
     3421 actcactcga ctttatcgga atttgccaga agaacagcaa aaagagtacc aagaaaaata
     3481 tgaacaagta aaaaaagacg tgcaatatgt gaaagatacg aaagtggaag aagcttgtag
     3541 tgatttattt ggagatacaa ttcctttttc aactagcgaa caagaacgaa aagaacgaca
     3601 acaatcagtc acatatgaac gctatgaaat cttgcttcaa caagcaacga acatacaaaa
     3661 tccaacgaaa aaagaaacgg cattaaatta tctaaaaagt gtcaaggaat ggttagatca
     3721 gcaacagcaa aattgaattt gatcggcaat catgttaaac taaacatgca aatgatcaaa
     3781 cattagatac acgaaagccc cagagaggtc ggattctctg gggctttttt tcaggttgat
     3841 gtcgccttta ttgattttac ttcttgtttc ggttattcaa ccaataactg aataaagaga
     3901 cacaaacttc tataagaagg gggcaaatga acaattcaaa cattagatac acctccttcc
     3961 agtcgcaaga ctgtcggata ggcgacaagt tattatatct taaaaaatta aacttgtgtg
     4021 gtgtttttaa gtatcgctta ttttagggtt gttagggctt gccctgaccg cctgtaaggc
     4081 gctttaaagc tagataagga tttttatcca agactgtctt aaaacggctt agataagcat
     4141 tcagaaccgc tcaaaggcct ctttaccaac atgtttttag caaaggagcc tttaggcgac
     4201 tgcgcagtac aatgtgagag cgtagcgatc acaccttttt ggcgaccgta ggaagcaagg
     4261 ttttggattg gcagttttga aaaatgcgcg aacctgttta aagaaaaaag aagtggtttt
     4321 taggcgggaa aattagcccc cctcttttta tatctctttt taaacctctt tttaaacctc
     4381 tttaccgtaa gctgtgtcct tactctacca atggatacag aatgttatga aggacatttt
     4441 gtctgtttat gaaggacatt ttgtctgttt atgaaggaca ttttgtctgt ttatgaagga
     4501 cattttgtct gtttgaacgt caaatatgaa tgtcttgaca tttaaaaaat gtcattcata
     4561 attggattga ggtgattata tggctaatga gattgtaaaa taccaccatg aattaaatac
     4621 aattccttta agaaaattta caccggttga aatgaatttg tttttttcca tcgtgtctag
     4681 aatgcgtgaa aaaggggata agacagttcg ttttacgttt gaccaactaa aagatttaag
     4741 taactacaaa gcaactgcaa atgtacgatt tgtagaagat ttaaaagcaa cttatgaaaa
     4801 aatcttatct ttacgctttg gtcgtagaag tgagtctggg ctttcttacg atatgtttgt
     4861 aatgtttaca gaatttaaaa tcaacgggga cgtagaaaat ccttacgtag atatacgaat
     4921 ttacgaaaaa gcactgcctt tgttaaataa tttagacgag tgggtacgct attctttaca
     4981 acaattcaac gagctacaaa gtggctatgc aaagactatg tttcgtctgt taaagcaata
     5041 cagaaccaaa ggtttcgcat atttctccaa agaagacttt cttgaattat tagatattcc
     5101 taaaagttat aagcaacctg atatagataa acgagttata aaacctatac gtcaagaact
     5161 aactgcaatc ttcaaaggac taacaatcaa aaagaaatac ggaaaaggac ggggaaaacc
     5221 tgttattggc tatcaattta cgttcaaacc tgagatcaaa aaagcagacg actttaacaa
     5281 acatgcacca accaaagaag accaaaataa agcattggct ttagctgata aacaaaaaga
     5341 atacgaagaa cccgctacaa caattaacga aaaaatcaaa cagaagaaac gagaacttga
     5401 actcctccaa caaatcaaac aactagaaaa agagaaaaaa gctcttgaaa aacaaacaga
     5461 gtccgcactt tcggaaaaag agaaaaaaag tttattatct gatttagata atttattcca
     5521 gtagcaacct aggaggcaac cagtatgcaa ccacaagaaa cctttacaat aaaggaattg
     5581 tcagatcttt ttaagatgag taggcaagca atatcgaaac atatccaaaa attagattct
     5641 tccatgatag ctaaaaatga gcgtggttat aaggttgtat tgcgttctgg agtattgcaa
     5701 cttgctcgca acttagacaa tcaaaggttg ctagataagt tgcataaaca tgaacaaaac
     5761 aacgataaaa atgcttatat accaaacaaa aacgtggttg caaacaagtt gctagatcag
     5821 ttgcgtgaag aaaatgaatt tttacgagaa caacttgccc tcaaagagca aaataattct
     5881 aatatgcaaa aattactcga ccagcaacaa cagctcaccc tacaggcaaa tcaacagatc
     5941 gaaaaattgc aagaacagtt acaattagct tatacggaag aaactccaga agatgaatca
     6001 actcctattc tttctgaaga aacagaatcg atagaaaaac acacaaaaaa gaagcaaaaa
     6061 tggtggcaac tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc
     6121 ggttctattt tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa
     6181 gggaataaac atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa
     6241 ttgtttgtaa aagaaacgga taaataataa aaaagactgc tttttcgagc agccagttaa
     6301 aaaaataatg agagtttatt cttgaaaaag cagcgcactt ataaagcgct accaaaaatt
     6361 tatcatattt tatgaaaaat aacaacccag taaaaaatga ctggtaaaaa ttcacaaaga
     6421 aacggaaaga agcaactgca gaaaatcaag ccttaaaaag agctttttac ctagaccaat
     6481 ccaaaatcac aaagtgagcc cctgtatcgg ttgatacaag ggctacttgg catactgtac
     6541 attatgttaa ctagctcgat aaataacgat tatgttccca aaacaatatt ttatgaacta
     6601 taacaaaaat ttgttatcgc atattgtata ttttaattat ataattatag gtgtatacca
     6661 cttaaattta acacaaagac gtgattattt tgaaacccaa aaagaaaatt tatctaggtc
     6721 tcctcttttc cttgatgatt ggaattttta gtataggaat tacaaatacc tatgcttcag
     6781 aaaattctaa tttcaatatc aactcccaac caattgaaga acaagcaatt aattttgcga
     6841 aaactgattt tgaacactcc ataacttcaa ttcttttaat ggaaaataac accgaaactg
     6901 atattaacta tactcttggt tcgccattta aaatgctcga tggagaaaat acggcaaata
     6961 gttctatttt ctttccagta ttttcagacg ctgataatac gattaaatat atttataccg
     7021 tc
//
LOCUS       DAIGQM010000095         6758 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.099, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000095 DAIGQM010000000
VERSION     DAIGQM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.099"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(193..1104)
                     /locus_tag="NOA48_002511"
     CDS             complement(193..1104)
                     /locus_tag="NOA48_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0790739.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1561..1989)
                     /locus_tag="NOA48_002512"
     CDS             complement(1561..1989)
                     /locus_tag="NOA48_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790740.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(2017..2655)
                     /locus_tag="NOA48_002513"
     CDS             complement(2017..2655)
                     /locus_tag="NOA48_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790741.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2659..4641)
                     /locus_tag="NOA48_002514"
     CDS             complement(2659..4641)
                     /locus_tag="NOA48_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCI0790742.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4821..5486
                     /locus_tag="NOA48_002515"
     CDS             4821..5486
                     /locus_tag="NOA48_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790743.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2178 a         1231 c         1021 g         2328 t
ORIGIN      
        1 tgatattgtt ttctttattt aagattatac agaaaaatat ctagggtcgc tggattctaa
       61 gtaaaaaaaa tttttaaaat aaaaagaact aaatcaagta gtaattaaac tactgttgat
      121 ttagttctaa taaaaagatt tagatgaaca gttttattga tttaaatagt tcatattttt
      181 tatttatacc gcttatttac tacttgctgt actagaatct gaagtgaatg tactcaaaac
      241 attttcaaag tctttgtctt tgatttttac attagcgtct ttcaatactt cgccaattac
      301 tttattctgg aaggtactgt cacttaattt tgtgtctgtt gcaatttctt tcaattcttt
      361 tttgtattta tccatgtcgt tgcctttgtt ttggtttttc accattttaa ccacataata
      421 ttccgtagta taagttgaag cattggtaga agtgatcaca tcagaaactt gaccatcttt
      481 caacttaaag gctgcttctt tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt
      541 cacttttccg ccatcttctt ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga
      601 gaaatcgtct cccttatcag cagctttctt cacatctttt gcatcatctt cacttgctac
      661 ttggataatt tgagcttcca cttctggatg gaaagattcc caagccgttt ttaaatcttc
      721 atcggtcaat ttgatatgtt tctttagacc ttcttgaaag gctagacttt gtttgatact
      781 gtctttgaat gtttgttctg tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc
      841 caattgtttc tttgtttgat catattgaga atcgatttct ttggttgata cgtcatctcc
      901 atatttatct tcaaatactt gataaacgat caactgttgc acagcggaat ctgctccttg
      961 catttttttc aagctatcca ttacttcttg ttcgctgatt gtaccgcctt tataactaac
     1021 ggctgttttt tcaccggcat tcgtacagcc tgacaataag ccagtgccta gtacgatggc
     1081 aagtgctaaa aatctttttt tcatttatca attctcctac ttttcgtttt ttgcgaattg
     1141 ctaaaaacaa aggtgttcaa gatgaaaatc atcaagaaca cctttactaa tctgctcgat
     1201 acgtcctgaa tagatataag gctacacaat ccagaaagtt cgctcagcag aataaatgtc
     1261 aagtagcaca tcacacctta atatactact tcttttgtta ccgtttttca agtctatctt
     1321 gcgttccgta tttaacgtaa ctaattctta gaacaaatgt tatcgatttt gtttttcttc
     1381 ttccgctgct gggatattca aatcagacac ttttatgttc gattttccag acattttttt
     1441 gttgttttta ttatgatata tttttataca actaaaaatg aatatattaa aactaccaaa
     1501 aataactttt aacgctgttt cattatatgt tttttctatt ttatataaac ttttggatac
     1561 ttaataccaa ccggttggat tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc
     1621 acttgcatag gcccatactc cttttgttgc atttgctgat cgaatagagt ttccaacttt
     1681 cgcttttgca ccgtgacgat tatagacacg actatagtgg ttagaatgac ctgtttttct
     1741 cgtacaagtt gtatcactat aataaaccca tcttccagag ctatgattaa ttgctgttct
     1801 agaaatttcc cggtctactg gtaaatttga cttaataata ttacctttag catcaaaatg
     1861 aatctctcct ggctttaaag atttgtaata gatttcaccg tgaactgaat ttgcttccac
     1921 ttcagatgac atagcgtttc ctccaacaaa acctatccct agtgcacaaa taataactgc
     1981 ttttttcata aaacgacatc ctttcctttt tgatttttaa agcatgatct tcttgtttcc
     2041 tattttggtc agatatggat catgcgtgac tacgataact aacgtacctt gggaagcttg
     2101 ttgcgataag atttcaacta ctttatcctt atttctttta tccaatgacc cagtcggttc
     2161 atcggctaaa atgattttgc tattcttcaa taagactctc gcacaggcga ttctttgctt
     2221 ctcaccacca gataatgtgt agataggcgt acttagcttc ttgtttatat ttactttttt
     2281 caatgcctca tactttgctg ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc
     2341 aatatctaaa ttaaaatcga ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa
     2401 agatatggta tttcttttta tcaagcgctt ctctctccca gttaattgtt tcgtctcttg
     2461 atcgaacaaa tagaattgtc ctgaactgaa ctgatcattc aatcctaata tattcaataa
     2521 cgtactttta cctgctccac tttctccaac aacagtcaca agatccccag catccgcagt
     2581 gaaacgatcc aaatgaagaa tcgttttgtt tcgaatgatt tttttcgcac cttttatcac
     2641 tatcaacggc tccaattgtt aacctccatt catcagcaat aactgacttt tcttttctgt
     2701 agacaaaata aaaacaactg aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa
     2761 aagatattta ggctctcttt ctataagaaa aaggaagatt acacttgtcg ttccccattt
     2821 gatgaggttc atcatgaaga aatctttata cgtttcaaag agcgaataac cacttgaacg
     2881 aaagatagcg attttccgac aattgtagac aaaatatatg cataacatga catagctcaa
     2941 caagaagaaa gaaaagaaag tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct
     3001 taacactttg acagctatct cttcagtctg agtatacgga aatgataact gcaagttatc
     3061 acgtaactga ctttcttcaa tcagctcaaa taacctttct ttcgacaaag agcctatctt
     3121 gatctttaac ggtggataga tttctccgct gagaatattt ctttccaaat acatactgtt
     3181 tttcaatgtc agtatttcaa caaccggata atgttcgatc caggggatag aaggaataaa
     3241 tgtataaatg ggttgattgt tttttataaa tagaaatttc ggttcttttt cactgatttc
     3301 ttgataatat tctgttattt gcgccaggtc attttttaaa tctgtatgtc tatatcgttc
     3361 agggatcaat ataacagggt gcgtttcttt ttcggttatt tggatcaacc ttccagagac
     3421 atcaatcaaa ggaaatttct taagataatt cagatttatt tttatccctc tgccaaactg
     3481 ttcattttct tcattcaagt aatctgatac attgactaat atacttccgt ttttattcaa
     3541 agtttcatat aattcctgat ctgctgctga tgcaaaacga ttggaataaa taaaatccac
     3601 gtggtttttc ccgatggtta ctggataaaa tacatgatag tcctcaccag cgatttcttt
     3661 tggtggttca tgggaaacag ctaactgtga agaagaaaaa acgatagttg ctaattcgac
     3721 attggcaacg gtcaaaagaa gagaaaacaa caatccaaat gtaaaaagaa tgtattggat
     3781 atagttgaac gcttctctta acgaagcgat tttttcaact aataaaagag aaatcaaaga
     3841 gataccatat attccgctga acaagaaaac gtacatctgg aacaaataaa gaaattgctc
     3901 cttataatac ataaaaataa aaccaccaat gattcctgca attatgaatg taataatgat
     3961 tttctttttc cccaataaac accacaatac ttgatgtaat gaaaagtcat tattcaacaa
     4021 taaactgatt tctttattca tcaataagaa aaaggatgat aacaaaagga ataaaagaat
     4081 caatccaata gttaaataca ctcgataatt atatacgtct gtatttgaaa taaccgaata
     4141 cgaatagcta ttttcaaagt cttcaaaaat attagtggca taatcagtgt gaaatgcttg
     4201 attgaatcga tcagtgaata gtgaaatgaa ccgttcatag gcttcttttt ctctcgtcat
     4261 caagaaaaat tcaccttcaa aatcttttat tttgatcgat tcttcaatgg acgttacgcg
     4321 aaaggaggta ttagaatagg gtaccttctc gtgagaagat ttgacatccc cttgataata
     4381 caatgtcatt tcaagctttg gctgtatctt gaagttccaa gatgtatcta cttcattgga
     4441 ttcatttact gtttttttca tataagaaag ctcagtttct gatgagacat tttcaaatac
     4501 catgattagc tgctcatatt cttcttgccc aataaaatgt tgtggcaatc gaatcggagt
     4561 ataagtatct gtttgatgga aaaattcatt tgtccgatag agtacctgtt tatttatact
     4621 aaccaaggca aaaccactca tgataccggt cactatgatt gtgagtaaaa ctgtgaactt
     4681 ttttttgatt atcaccactc tcccttactt aaatgattct ttgataaaat cataccgttt
     4741 ttcatcaaaa aaacgtatct atcaagtgta taggtcatgt agaataaatc tatatactgt
     4801 agaatcgaaa ggagaagaag atgaacaccg gagaaaaaat acgaacttac cgcagaaatt
     4861 gtaagcttac gcaaaaagaa ttaggcgaaa aaattggtgt ttccgataaa acgatttcta
     4921 gttgggaaaa ttctcgtaca atgccagacc ttgaaatgct gtcactttta catcatactt
     4981 taggtctgcc gattgatttt ccttctattg aatcagctac cgaatcaata gaaccaacat
     5041 tgccagatga acctcttgtt aacaagaaat cttattcatc aaaacaaccc ttctcactca
     5101 aaaagacact atctttcttt ctgctcgtct tttgtttggt ctatcttttt cttatcaatt
     5161 atcaatacaa aaatgaaacg atcgatcgat tcaatccttt tttgaaacca caaatcggct
     5221 ataccacact ccctgtagga tacgtggaca attccatcga acgttgggta tgtaatgata
     5281 tctttggcca tggtacatgg ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc
     5341 atgctgtaat caaacacaaa ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag
     5401 ccattccctc agattaccaa gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa
     5461 gccctcagga gccagatagg cattaagtag gagatgaacg tagagataga aaaaatcaat
     5521 gcacatgatc ttatccaaaa aacaggggta caaattaatt gaaaaagcct tgagatgaaa
     5581 gttcctaaat aaaaaagttc agaatgatag gtatttctgg cttatagtat aatatttacg
     5641 ccacagcctc ccaatgattc tttttggaat cataatcaag gatggacatt cacaaaaata
     5701 ttttgctcat tcgatccgaa tagattaacg accaatctag taagtaatat agattggtac
     5761 gtagtcaagc tgcacataat ttagatcaat tttagttctt ttttatattt ctatgatctg
     5821 ctcatttact tttatatgat ggcttacagt aacataaata aatatgataa tcgctggtag
     5881 tttatccaag agtactcaat aaaatacaaa atggattgtt caagcgccta tcataatgat
     5941 aaaatgaaac aaataaacga tacaaggagg aagagacttt gagtaatggc agaacaattt
     6001 tttcattgta aaaattgttc agttgttaat ctatgggatt tcggtagcat gggcattttt
     6061 ttatagagga atcacaccaa cctggccgtt ttatctcttg ttagtgggaa tattagtagg
     6121 aaattttgcc cctcttcact atcgtacgaa cttttttcca actgattctg gcctttttct
     6181 taaaacaaag acgcgaaaat tagaaaacat tattgaaatg acaattacct gtataatcat
     6241 tttcttagtt atattcctaa acgtcttcta ataagaatct cttaaaatta gcttgttaca
     6301 gttagttacc tagtttatat aacacagtta tcttatcttc cttatcaaca tcttttgcca
     6361 actctttgtc ttaaattcga aacatataag cagagctacg aacaccaaga ctgtttcggc
     6421 tctgtttttt gcatcaaatt cactcttata tagctgataa tctcggctct ttaaaagaaa
     6481 ttattttcgc ttcattttat tataaaaagg ctaggaacct tgatgttatc aggttcctag
     6541 cctttattta agtattaccc cacagaccct tccatataga tttttaaatt acacactagt
     6601 ttaaactaaa acaaacaagg aaacacttac catttaatca taaaattagc tcatatgaat
     6661 atattagaat gtaaaataga ctggtcaaaa tctggtcaaa aaagaggact aatacaggta
     6721 gtcctcagac tgtagacaaa gtccatttta tggatgat
//
LOCUS       DAIGQM010000096         6558 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.100, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000096 DAIGQM010000000
VERSION     DAIGQM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.100"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            123..1394
                     /locus_tag="NOA48_002516"
     CDS             123..1394
                     /locus_tag="NOA48_002516"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0790744.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            1391..2686
                     /gene="rho"
                     /locus_tag="NOA48_002517"
     CDS             1391..2686
                     /gene="rho"
                     /locus_tag="NOA48_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCI0790745.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            2785..3048
                     /locus_tag="NOA48_002518"
     CDS             2785..3048
                     /locus_tag="NOA48_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCI0790746.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            3493..3942
                     /locus_tag="NOA48_002519"
     CDS             3493..3942
                     /locus_tag="NOA48_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0790747.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            3999..5417
                     /locus_tag="NOA48_002520"
     CDS             3999..5417
                     /locus_tag="NOA48_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0790748.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            5417..6277
                     /locus_tag="NOA48_002521"
     CDS             5417..6277
                     /locus_tag="NOA48_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCI0790749.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            6451..>6558
                     /locus_tag="NOA48_002522"
     CDS             6451..>6558
                     /locus_tag="NOA48_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI0790750.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEA"
BASE COUNT         2173 a         1156 c         1454 g         1775 t
ORIGIN      
        1 ttttgaagtc gctctccatt cttttttact taaaacggca gaccatgctc gtttcttttt
       61 tttatctatg ataaaataca agcatatcca tgaaaaaaga ttaataaaca aggtggaaac
      121 agatgaaaaa aatcgtaatc aaaggaaacc gacctttagc tggtgaagta acgatcagcg
      181 gtgcaaaaaa tagtgcagtc gcattgattc cagctgcaat cttagctgat tccccagtga
      241 tcttggaagg tgtgccggac atacaagatg ttcattcatt aattgaaatt ttagagatca
      301 tgggcgcaac tgtccatttt tccaacaaca tactagaaat cgatcctcga gaagtcgtat
      361 cgattccgat gccgcacgga aaaatcaata gtttgcgtgc ttcttattat tttatgggaa
      421 cactgcttgg taaatttggc gaagcggtag taggcctgcc aggtggctgt tatttaggcc
      481 ctagaccgat tgacctacac gtcaaaggat ttgaagctct aggtgctgaa gtgacaaatg
      541 aacatggtgc catgtattta cggacagaaa ataaaggatt gcgtggcaat cggattttca
      601 tggacgtggt ttcagtcgga gcaacgatca atgtgatgtt agctgctgta aaagcaaaag
      661 gacagacagt aattgaaaac gctgcacgag aaccggaaat catagatgtg gcaactttac
      721 tgaataatat gggggcaaaa gttcgaggag cgggtacaga tgtgatccgt atcgaaggag
      781 tcgaaacatt acatggctgt cggcatttca tgattcctga ccgcatcgaa gcaggaacct
      841 atctagcatt agcagctgca gtaggaaatg gtatcaaagt gaaaaatgtg atctttgaac
      901 atttggaaag ctttatagca aaattgcagg aaattggtgt ccatatgaaa atcagcgaag
      961 atgaaatcga agtttacccc tcgaaagaat taaaacccgc aaacatcatg acctatcctt
     1021 atccaggatt tgccacagat ctgcagcagc cacttactgc gttactattg atgactacag
     1081 gcacttcaga aatcatcgat acgatctatg cgaaacgtgt gaaccatgtg ccggaactag
     1141 cacgaatggg cgctgatatt accgtggaag gaaatatgat catcgtgaat ggtccaaata
     1201 aacttcacgg cacagaagtc gtggcttctg atcttcgggc aggtgcttgt ttagtgattg
     1261 ctggactatt ggcagaaggg acaacgacga tttacaatgt agattatatc ttacgcggtt
     1321 atgatcatat tatcgagaaa ctaacagcct taggggcatc aattgaaatg atagaggaag
     1381 tgggagctga atgagcgatt atttgacaat ggcagaacta gagaacaaaa cgttaaaaga
     1441 agtttatagt tatgccaaag aatttaaaat tccttattac agtaagatga ataaaaagga
     1501 attatctcta gctgtgattc gtgcacaagc agagaaacaa ggattttatt atatggaagg
     1561 aatattggat atcgttggtc aagatggtta cggtttttta cggccaatca attatggacc
     1621 aagtgcagaa gatatctata tttctgcctc acaaatcaga cgattcagtt tgagaaatgg
     1681 ggacaaagtg gcaggaaaag cccgtccacc taaagaatcg gaacgttatt atggtttgat
     1741 gcacgtggaa agcgttaatg gaaaagatcc ggaagaagca aaagaacgtc cgcattttcc
     1801 agccttaaca cctctttatc cgcaaagaca gcttcaactg gaaacaacac cgcaaagact
     1861 atctacccga atgatcgata tcttttctcc aatcggtttt ggtcagcgtg gattgatcgt
     1921 cgcaccgcca aaagcaggga aaacttctgt attaaaagaa atcgcaaatg gtatcaccga
     1981 aaactatccg gaagtagaat taatcgttct actgattgat gaacgaccgg aagaagtaac
     2041 ggatctagaa cgaagcgtga aaggcgacgt ggtatcttct acatttgatc tgcagccgca
     2101 aaaccatact cgagtttctg aattagtatt ggaacgcgca atgcgtttag tcgaagataa
     2161 acgagatgtc gttatcttga tggatagtat tactagactt gctcgggcct ataacttagt
     2221 cgttccacca agcggacgta cattgagtgg cgggattgac ccagccgcat tgtataaacc
     2281 taagaaattt ttcggggcag caagaaacat cgaagaaggt ggcagtttga cgattttagc
     2341 gaccgcttta gtcgatacag gaagccgtat ggatgacgtg atctatgaag aattcaaagg
     2401 aactggaaat ctagaattac aactttcacg tgaattatct gaacgtcgga tcttcccagc
     2461 catcgatatc aaaaaatcag gtacccgaaa agaagaatta ttgatgccaa gtgaagaatt
     2521 agaagaaatt tggaaacttc gaaaaaatat gactggagat tcattagaat atacggaaca
     2581 actgatccgc tttttgcgta aaacaaaaaa caatcagcaa tttttcaaag aatttcaaga
     2641 tgtctccttt ggtaaaaaaa atccgaccag aaatctgaaa agataattgc aaccttgact
     2701 gaaacatgtt aagatgttaa tgttgtaaat cgacaaatca actctggttc agcaaatgga
     2761 gcagggcaaa ggagcgaaaa aatcatgaaa gaaaacatcc atccagatta ccacccagta
     2821 gtattcatgg attcaacaac tggtttcaaa ttcttgtcag gttcaacaaa aacttcacaa
     2881 gaaacagttg aatgggaaga cggtaataca tacccagtca tccgtgtcga agtaacttct
     2941 gactcacatc cattctacac tggacgtcaa aaattcacac aagcagacgg acgtgtggac
     3001 cgtttcaaca aaaaatacgg tctcaaagac gcaaacgctg cggaataata aaaacgctga
     3061 taactcaacg tttagcagac tatctgatag ggatagtctg tttttttatg ttttttgcca
     3121 atttaaaact tcgtttgatg ctgaaaaagt cgtaggatca taatgcacaa aacaatgaaa
     3181 aactagtata tagttttaat tatccacttg ataaaaacac cttatattaa cgaaatgaag
     3241 aggggttatt tcgaagtaaa aaaccattta cctaaaatta gaagctaagc tttcctttca
     3301 aggaaggctt tttgttttgt tatagacttg cgattgtttg tgagctagat cgttcatttt
     3361 aatgacttat acacgcggat gatgggtctt tttcctctgt tcattcataa tattgaacgg
     3421 tacagctagc gatgctatac tgacctcagt tccaagaaaa cgttaacatt ttttgtgggg
     3481 gagaggtttt ttatgaggtt tgatcaattg atcgcagaag aactgattgt tttcgatcca
     3541 tcgatagatt caaaaggatc attatttgag cgaatagggg atgtgttgaa aaaaacaaat
     3601 aaggtaagaa atgttcaaaa agtcgttaag gcactattca aacgagagga ggagatctcc
     3661 acaggaatag aagatggatt tgggattccc catgcaaaaa gcaaatatgt gacaaaacca
     3721 gcactgtgtt tttttcatac agccaaatta acggactata gcgggataga tgaaatgcca
     3781 attgaatata tttttgccat cgtagttcct gaaaaatcag cagatatgca tctagagatt
     3841 ctcagcacac tctccagacg attgatgaat gcagatttta gaaagggaat aaaagaagcc
     3901 actacgccag cagatatcat cagacagatt agtcaagaat gaaaatagta gagtctttgt
     3961 ccgagtatcg atagtgaaga aaaaggagga aaataatcat gaaaatcgtt ggtgtaactg
     4021 cttgcccgac tggaattgct catacttata tgtcggcaga aaaattagaa gtaacagcaa
     4081 gaaatctaaa ccatcaagca aaattcgaaa cacaaggtgt aaaaacagaa aatcagttat
     4141 ctgaacaaga aatcaaagag gcagatgcaa tcattcttgc agtagataaa gaaatcgaat
     4201 tggaccgatt tgccgggaaa aaagtaaagc gtgtctctac aagccgagca atcaaagaac
     4261 cgcaagtagt aatagacgaa gcattgagag atattggcgt attcgttgtg tctaatgaaa
     4321 aagaaccagc tgcaaatgag aaaaagccga caatctataa tcatttcatg aatggtgtga
     4381 attacatgct tccatttgtg atcgcaggcg gaatcatcat cgcactgagt tttgcctttg
     4441 ggattacagc ggctgatccc aactcagcag actataatgt gttagcagct gcattttcaa
     4501 ggatcggagg agatacagcg tttgccatga tggttcctgc gttaggcgcg gggattgcta
     4561 catcgattgc tggaaaagca ggttttgccc caggaattgt tgccggatta ctggcctcta
     4621 caggtggttc aggttttctt ggcggaatga ttggtggcgt gctagcaggg tatatctgtg
     4681 attttctggc aaataaaatt agcgtaaaaa aagaattttc tgctatttat cagctgattg
     4741 tcgtcccctt tttatcgatc ttaattattg ggcttttgat ggtatttgtg attgaacaac
     4801 cgatcacatg ggtgttggat gctttgacaa attggctgaa tagcttggga aatacatccg
     4861 ggctattgtt cggattactt atcgggatca tgatggcagc tgatatgggt gggccgatca
     4921 ataaatcgac ttcgactttc tcgatcggtt tgatgtcagc tggagtaaat gcaccgattg
     4981 ctgcttgtat ggctgcagga atgacacctc ccctaggtat tgctttagcc actttattat
     5041 tcaaacataa atttaccaaa gaagaacgga cttcaggtca atcatgctgg attttaggcg
     5101 cttcgtatat tacagaaggt gctataccgt ttgcggtatc tgacccgatc cgcgtgatac
     5161 ctagtttgat gacaggttca gcagtcgctg cagggatttc catggcagta ggagttactt
     5221 caatggcacc tcatggaggg atttgggtga tgctaattcc aaatgttatg aacaatttac
     5281 ctatgtatgt cttggcaatt gcatcaggta cagtcactac agcctttatg cttggactat
     5341 tgaaaaaaac agtgaaagag aaaaaacaag acaagtggac gaaaaatgaa aatctaacaa
     5401 atgaggtgga agcgtaatgt tatatacaat gaaagagtta ttgaaagtgg ctaaagagaa
     5461 tcaatttgca gtaccagcct tcaatatttg cagctatgat atgatgaaag caatcatcga
     5521 agaagcagag agattagaag caccagtaat cttagaaatt catcctgatg aaatcgccta
     5581 tttaagtgat gagtttgttg cggcagtaag agcctatgct tatacaagta aactgccgat
     5641 cgttatccac ttggatcatg gcggtacgat agaagatgtc ttacgggcga ttcgaaacgg
     5701 ctattcttcc gtgatgatcg atgcgtcttt gaaatcattc gacgacaatg tacagattac
     5761 gaaaaaagtg gttgcgttag ctcatgcggt aaatgtctca gtggaggctg agcttggaac
     5821 gattgggaat aatggttctg ctgaaggagg tgctgaaaca atcatttata cagatcctga
     5881 tcaagcgaag atttttgtga aagaaacagg aatcgataca cttgctgtag caattggaac
     5941 agcgcatggc ttgtatccga aaaacagaac tccaaaatta aatatcgact tactgaaaga
     6001 attgaaccaa caaatcgatc ttccatttgt tttacatggc ggttcaggta atccggacgc
     6061 agaagtcagc gaagcagtaa aatacggagt tgccaaagtg aatttgagct cagatcttaa
     6121 aagcgtcttt ttcaatgctt tgagagaaat attgagtgaa aatccatcga tgtacgagcc
     6181 gaatgcaatt tatccagcag ctaataaaaa ggtacaagaa gtggtcaaac ataaaatgga
     6241 aattttgaac acagtaggca aggctagttt atactaaaaa taaaaatgtg tggtcaagag
     6301 ggtatgacaa tagtcttgtc ataccctctt aaccacacac gatgttcaga agtagttttt
     6361 tcgaaaaatt tcttcttatt tctcgaagcc aatcacttct gtcacaacct cttttttcct
     6421 gttactatat aaagtaaatg gggtgatttt atgttgaatg aagtggagaa tagacagcag
     6481 gagattgtga attatctaaa aaacaaccaa tttgcaagag tcaccgattt gatcgagtta
     6541 gtaaattata gcgaagcc
//
LOCUS       DAIGQM010000097         6381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.101, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000097 DAIGQM010000000
VERSION     DAIGQM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.101"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            152..2095
                     /locus_tag="NOA48_002523"
     CDS             152..2095
                     /locus_tag="NOA48_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0790751.1"
                     /translation="MLSKRESQLIELLLEEENFQPASFFSEKLNVSNKTIYQDIQKLG
                     QFLNRFELKIEKKPRMGIYLIGTSTKKNDAKIFITSKEAMSTKVKYSSNYRRVYLFAN
                     LIFKTDKKRYEYFEKKFFVSIATLRKDYEEIIKYCRLAGIRITSNHVIDTQKTPEELI
                     QRTFVNYFEKNIGVGNEKCQYHFVFDQAMVKFVDDFVKNFYQQSKQQPTNYIVHSLKL
                     SLLTLIGRVKHGYHSQTNKNPLFVEIKKMELYMVALDFSNGVKDELNCSFTINDLYFI
                     CSLFMGHGVRPFVNLATHSQQIMETTKQFIQDMSTLVEKDLGQDSQLLQSLFAHIEPM
                     VYRLQMGITIKNPLKEDIIRQYSTMYTLATYCIPKLEKAMGIRVTDDEITFLTIHFQL
                     AFEKIVNTKHVFLICPTGLGTSQLLFQRIRHSSPSTVVYEVIDVQKLQDYNLDSVDLI
                     ISTVKLENEYQTPVIYVRPLPTKEEIALINRHLLTLNQQDNTFLPSIAPDKTILKKYL
                     KDGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFLEVVLQREKLGATGLSSGVAIPH
                     ANPKYVVKTKISIITLKNKITWGDVDIRVVLFLAIAEEDMIQVKNMIALLYDVFVSPE
                     RIKSIASKETRNEIINEIIGKRK"
     gene            2097..2558
                     /locus_tag="NOA48_002524"
     CDS             2097..2558
                     /locus_tag="NOA48_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0790752.1"
                     /translation="MTSYFGKKIALFQSEVKSQKEALSIIATCLYQTGLVKDSFAENV
                     LKREEVFPTGLLINDVGIAIPHTDAEHVNDSQIAFMSLKTPVTFYEMGTADKEISVSL
                     IFMLALKEPHAQLEMLQKLITMFQKKEVVQKLRAVNNTEEYYQIIEKEGFV"
     gene            2582..3928
                     /locus_tag="NOA48_002525"
     CDS             2582..3928
                     /locus_tag="NOA48_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0790753.1"
                     /translation="MLDLLQKFVDLGSIVVLPILIFVFGLILGTKPSKAFISALTVGV
                     GFVGLNLVIDLLTNSLGPAAQAMVERFGLNLTTIDVGWPAAAAISYGTVLGSLAIPVA
                     IVVNVLLIIVGLTKTLNVDIWNIWHAAFVASLVYAVTNDFAMGMLATVIYTMMILLFG
                     DILGPIINKFYGFPNITFPHGTSAPGFVFALPLNWLFDRIPGLKDWHADPETIQKRFG
                     IFGDSTVMGFLIGLVMGILAGYDVAGIGQLAVKTGAVMVLMPKMVALLMEGLTPISES
                     ANSFVQKRFPGRELYIGMDAALSVGHPAVLSSSLILVPITILLAVILPGNTTLPFGDL
                     ATIPFLICLMAAVFGGNIIRTILGGTIYMVTILYITSWVAPFLTKAAQGANFDLQGHS
                     SVTAMAEGGLWTTLLYVGGAKLFGYFALVGIGLIITGLLFYVNRILPKRAAKQTEA"
     gene            3951..4235
                     /locus_tag="NOA48_002526"
     CDS             3951..4235
                     /locus_tag="NOA48_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0790754.1"
                     /translation="MKKLLIMCGTGVATSTVVTGKVKEWLKSKGLENEVKLYQSKVAD
                     EIGKIDDYDIVVSTTVVPDNIKDKVIMGLPLLTGIGIDGLFDEIEAKIKA"
     gene            4262..5089
                     /locus_tag="NOA48_002527"
     CDS             4262..5089
                     /locus_tag="NOA48_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HCI0790755.1"
                     /translation="MLVTTKEMFEKAQKENYAIPAANFFDLDSARTFVEVAEKMQKPL
                     ILAFAQAHIEECPLEEAALIATYLAKKASVPVALHLDHGQDEEIIKQAIELGFTSVMI
                     DASQDEIETNIRRSKAIAEYAHERGVVVEAEIGHVGTGNSYEFKETTDTIYTEVEEAA
                     RFAKETGVDSLAVSIGTAHGQYKGTPKISFERLEEIKNEVSIPLVLHGGSSSGDENLH
                     KCAVSGINKINIFTDFITAAMDVINEEKPEDYFTLKRLANQAIADTLSHYYEVFATK"
     gene            5102..5797
                     /locus_tag="NOA48_002528"
     CDS             5102..5797
                     /locus_tag="NOA48_002528"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI0790756.1"
                     /translation="MRTVRKPFFVVNPKSYLYGEQALKLAKTADQLAAAYDIDIIFTC
                     QHVDVRLIKEQTTQLIVSVQHIDGIVPGRGMGHVLPEGVVAAGAEATFLNHAERPLSV
                     SELCDAVKRAKELGLLTIVCANSLEEAKLVASLKPDVMVCEPTELIGTGQASDISYMI
                     QTNEAVRKMDPEIFVLQAAGISTVADVRKALDSGADATGGTSGIVCAKDPVDTLKAMI
                     EEVSKWKKEQSTK"
     gene            5794..6309
                     /locus_tag="NOA48_002529"
     CDS             5794..6309
                     /locus_tag="NOA48_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016380999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HCI0790757.1"
                     /translation="MITYTEQLVLTSNGQRVTYHNITEQVKEIVAKSGIKNGICLVQS
                     PHTTCSVIFEEFMHDLDFNGDEFLQVDLNRILDRIIPRELTENTDYRYPGPKHLDFLL
                     SLDDPDYAGDAGTILNGDAHIRASFFGASENFIVKEEILMTGTVGSIYFIDFDQNRVR
                     NRKCHILVMGE"
BASE COUNT         2114 a          968 c         1362 g         1937 t
ORIGIN      
        1 ttaaaaaaat tgtcgtgagt tttactgaca tcaaaaagta tagggtcata ataatctgtt
       61 ccacattaat gtggaacaga ttacgtattg atctttagtg agaaaaactc tatgatatag
      121 acaaggaaaa cgttttctga ggtgatgatg gatgttatca aagcgcgaga gtcagttaat
      181 tgaattactt ttagaggagg agaattttca accagcaagt ttctttagtg aaaaactcaa
      241 tgtttcgaat aaaacaattt atcaagatat tcagaagctg ggacagttcc tgaatcgttt
      301 tgagttaaaa attgaaaaaa aacctcgcat ggggatttac ttaattggaa cgtcaactaa
      361 aaaaaatgat gccaaaatat ttatcactag taaagaagct atgtcaacaa aggtaaagta
      421 tagttcaaat tatcgtagag tgtacttatt cgccaatcta atttttaaaa cggataaaaa
      481 aagatatgag tattttgaaa aaaagttttt tgtcagtatt gcaactttgc gtaaggacta
      541 tgaagaaatc atcaaatatt gtcggttagc tgggattagg attacttcaa atcatgtaat
      601 agacacacaa aaaacacctg aagagttgat ccagcggaca tttgttaatt attttgaaaa
      661 aaacatcggt gtagggaatg aaaagtgtca atatcacttt gtttttgatc aagcgatggt
      721 taagtttgtg gatgattttg taaaaaattt ttaccaacag tctaagcagc aaccaacaaa
      781 ttatattgtc cattcactca aactttcgtt gttgacgttg attggtcgag taaagcatgg
      841 ctaccattca caaacaaata aaaatccttt gtttgtcgaa ataaagaaaa tggaattata
      901 tatggtggca ctagattttt caaatggggt caaagatgaa ttgaattgtt cctttacgat
      961 aaatgatctt tactttattt gttcgttgtt tatgggacat ggagtgagac cgtttgtgaa
     1021 tctggcaacc catagtcaac aaatcatgga gaccaccaaa caattcattc aagatatgtc
     1081 gacactggtt gagaaggatt tggggcaaga tagtcagctg cttcaatctc tatttgccca
     1141 tattgagcca atggtttatc ggttgcaaat ggggattacc attaaaaatc ctttaaaaga
     1201 ggatatcatt cggcaataca gcacaatgta tacgctagca acttactgta ttccaaaatt
     1261 ggaaaaagca atggggatca gagtaacgga tgatgaaatt acttttttga ctattcattt
     1321 tcagttagct tttgaaaaaa ttgtgaatac gaagcatgtt tttcttattt gtccaacggg
     1381 gttgggaact tcgcaattat tatttcagcg tattcgtcat agttctccta gtaccgtagt
     1441 ctatgaagtg attgatgttc aaaagttgca ggattacaac ttagatagtg tcgatttgat
     1501 tatttcaaca gtcaaattag aaaatgagta tcaaacgccg gttatttatg ttcgaccatt
     1561 accaacgaaa gaagaaattg cattgattaa tcgtcatctt cttaccttga atcaacaaga
     1621 caatacattt ttaccatcca ttgcaccgga taaaacgatt ttaaagaaat atttgaagga
     1681 tggttggatg tttttgaatc aagattttga tagtagagaa tctgtacttt ctttcatcac
     1741 tgagaaatat aaagaagaac aattagtaaa ggataatttt cttgaggttg tacttcaaag
     1801 agaaaaacta ggagctaccg gactttcatc aggcgtagcc atcccacatg caaatcctaa
     1861 atatgtagtc aaaacaaaaa tttctattat cactctaaaa aacaaaatta cttggggaga
     1921 tgtggatata agggttgttt tattcttagc gattgcagaa gaagatatga ttcaagtgaa
     1981 aaatatgatt gcactacttt atgatgtctt tgtctcacct gagagaataa aaagtattgc
     2041 aagtaaagaa acaaggaatg agattattaa cgaaattata ggaaagagga agtaagatga
     2101 cgagttattt tggaaagaaa attgcattat ttcaatctga ggtaaagagt cagaaggaag
     2161 ctttatcaat tattgcaact tgtctatatc aaacaggttt agtgaaggat tcgtttgcag
     2221 agaatgtact gaaaagagaa gaagtgtttc ctactggctt attaatcaat gatgttggga
     2281 ttgctatacc acatacggat gcagaacacg tgaatgattc tcaaattgca tttatgtcat
     2341 tgaaaacacc agtaactttt tatgaaatgg gaactgcaga taaggaaatt tcagttagct
     2401 tgatcttcat gttggcgttg aaagaaccac atgcacagtt agaaatgtta cagaagttaa
     2461 ttacgatgtt tcaaaaaaaa gaggtggttc aaaagcttcg agctgtaaat aatactgagg
     2521 agtattatca aattattgaa aaagaaggat tcgtttaata accattttga gggggagcat
     2581 tatgttagat ttattacaaa aatttgttga tctcggatca atcgttgtat tgccaatctt
     2641 aatttttgtt tttggtttga ttttaggaac aaaaccgagt aaggctttta tttcagcatt
     2701 aacggttggt gttggatttg tcgggttgaa tttagttatc gatttattga ccaatagctt
     2761 aggaccagca gcacaagcga tggttgaacg ttttggacta aacttaacaa ccattgacgt
     2821 tggttggccg gcagcagctg cgatttctta tggaaccgtt ttaggtagtt tggcgattcc
     2881 agtagctatc gtagtcaatg tgttattaat tattgttggc ttaacaaaaa cactgaatgt
     2941 tgatatttgg aatatctggc atgcagcatt tgttgcttca cttgtctacg cagtaacgaa
     3001 tgactttgca atgggcatgt tggcaacggt tatttataca atgatgattt tattgtttgg
     3061 cgatatttta ggaccaatca tcaataaatt ctatggattt ccaaatatta ccttcccaca
     3121 cggaacatca gcacctgggt ttgtttttgc cttaccttta aattggttat tcgataggat
     3181 tccaggattg aaagattggc atgcagatcc agagacgatt caaaaacggt ttggcatctt
     3241 tggtgattca acagtcatgg gctttttaat tggtttggtt atgggaattt tagctggcta
     3301 tgatgttgcg ggaatcggtc aattagcggt gaaaactggt gctgtaatgg tcttaatgcc
     3361 taaaatggtg gcacttttaa tggaaggctt aacacctatt tcagaatcag caaattcatt
     3421 tgttcaaaaa cgtttcccag gaagagaatt atatatcgga atggatgccg cattgtcagt
     3481 aggacaccca gctgtattgt cttcttcgtt aatcttagtc ccaatcacga ttttattagc
     3541 agtgatttta ccaggtaaca caaccttgcc tttcggtgat ttggcaacta ttccattctt
     3601 aatttgtttg atggcagctg tctttggtgg aaacattatt cgaacaatct taggtgggac
     3661 gatctacatg gtcaccattt tatacatcac ttcatgggtg gcaccatttt taacaaaagc
     3721 agcacaaggg gcaaactttg atttacaagg acattcatca gtaactgcga tggcagaagg
     3781 tggactgtgg acaacacttc tatacgtggg tggtgcaaaa ctatttggtt actttgccct
     3841 agtcggaatt ggtctgatta ttacaggctt actattctac gtgaatcgca ttttacctaa
     3901 aagagcagct aaacaaactg aagcttaata caaaatagga gagatgacag atgaaaaaat
     3961 tattaattat gtgcggaaca ggtgtggcta cttcaacagt ggtaacagga aaagtaaaag
     4021 aatggttgaa atcaaaagga ctcgaaaatg aagtgaaact atatcaatca aaagttgctg
     4081 atgagattgg caaaattgat gactacgata ttgtggtcag tacgaccgtg gttcctgaca
     4141 acattaaaga taaagtaatt atggggcttc ctttattaac cggaattggc attgatgggt
     4201 tgtttgacga aattgaagcg aagattaaag cctaaaaaat acttgaaaag aaggtaatca
     4261 aatgttagtt acaacgaaag agatgtttga aaaagcgcaa aaagaaaact atgcgattcc
     4321 ggcagcaaac ttttttgatt tagattctgc aagaaccttt gtagaggttg cagaaaaaat
     4381 gcaaaagcca ttaattttag cctttgcaca agcgcatatt gaagaatgtc ctcttgaaga
     4441 ggcagcgtta attgcaacat atttagccaa aaaagcaagt gttccagtag cacttcattt
     4501 ggatcatgga caagatgagg aaatcatcaa gcaagcaatc gagcttgggt tcacttctgt
     4561 gatgatagat gcttcgcagg atgagattga aacaaatatt cgtcgttcaa aggcgattgc
     4621 ggaatatgct catgaaagag gcgttgtggt agaggctgag attggacacg tgggaacggg
     4681 aaatagttat gaatttaagg aaaccacgga caccatttat accgaagtgg aggaagcagc
     4741 acgttttgcg aaagaaaccg gcgtcgattc attggcagtt tcgataggta cggctcatgg
     4801 gcaatacaaa ggaacaccga aaatcagctt tgagcggttg gaagaaatta aaaatgaagt
     4861 ttcaattcca ttagtgttgc atgggggctc atcatctggt gatgaaaatc tccacaaatg
     4921 tgctgtttca gggatcaata aaattaatat ctttactgat tttatcacag cagcaatgga
     4981 tgtaattaac gaagaaaaac cagaggatta ttttacactt aaacgattag cgaaccaagc
     5041 gattgcggat acgttatcgc attattacga agtatttgca acaaaataga ggagggttct
     5101 catgagaaca gtaagaaaac cattttttgt ggttaatcct aaatcttatt tgtatggtga
     5161 acaggcattg aaactagcaa aaacagcgga tcaattagct gcagcatacg acatcgatat
     5221 catttttact tgtcaacatg ttgatgttcg gctaattaaa gaacagacaa cgcagttgat
     5281 tgtgagtgtt caacatatcg atgggatagt ccctggtaga gggatgggac acgttttacc
     5341 tgaaggcgtt gtagcggctg gagcagaagc gaccttcctt aatcacgcag aacgtccttt
     5401 atcggttagt gagctgtgcg atgccgtcaa gcgagcaaag gaacttggtc tattgactat
     5461 tgtttgtgca aattctttag aagaggctaa gctcgtagct tccttgaaac ctgatgtgat
     5521 ggtttgtgag cctacggaat taataggtac aggtcaagca agtgacattt cttatatgat
     5581 tcaaaccaat gaagctgtac gcaagatgga tcctgaaatt tttgttctgc aggcagcagg
     5641 gatttcaacg gtagcagatg ttcgcaaagc acttgattcg ggggctgatg caacgggtgg
     5701 aaccagcggg attgtttgtg ccaaagatcc tgtggacaca ttgaaagcga tgattgaaga
     5761 agtaagtaaa tggaaaaagg agcaatcgac aaaatgataa cttatactga gcaacttgtt
     5821 ttgacttcaa atggacagcg agtgacgtat cataatatta ccgaacaagt aaaagaaatt
     5881 gtggcaaaaa gtgggataaa aaatggcatt tgtcttgttc agtcgccaca tactacttgt
     5941 tcagttattt ttgaggaatt catgcacgat ttagatttta atggggatga atttttacag
     6001 gttgatttaa atcggattct tgatcgaatc attcctcgag aattaacgga aaataccgat
     6061 tatcgttatc ctggtccgaa gcatcttgat ttcttgctgt ccttagatga tccagattat
     6121 gctggtgatg ctggaacgat tttaaatgga gatgcacata tccgagcatc attcttcgga
     6181 gcaagtgaaa atttcattgt caaagaggaa atactaatga caggaactgt cggctccatt
     6241 tatttcattg attttgatca aaaccgtgtt agaaatcgaa aatgccatat tttagtaatg
     6301 ggtgaataga aaagtaataa gaaacaaaca tttgggaaac taattgaatg atcacaccta
     6361 taaaaattaa tacgaaagat a
//
LOCUS       DAIGQM010000098         5983 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.102, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000098 DAIGQM010000000
VERSION     DAIGQM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.102"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(48..917)
                     /locus_tag="NOA48_002530"
     CDS             complement(48..917)
                     /locus_tag="NOA48_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCI0790758.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(1209..2819)
                     /locus_tag="NOA48_002531"
     CDS             complement(1209..2819)
                     /locus_tag="NOA48_002531"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCI0790759.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOA48_002532"
     CDS             complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOA48_002532"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCI0790760.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(5380..5772)
                     /locus_tag="NOA48_002533"
     CDS             complement(5380..5772)
                     /locus_tag="NOA48_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0790761.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1755 a         1278 c          982 g         1968 t
ORIGIN      
        1 caaaagtcgt tctccattcc tatatatcgt atctgttatg tggatgctta cgctttgtta
       61 gctgaaccga accagtcgat atgagattta gcatcttcaa cgattgctgc tttacctgga
      121 gctaataatt tacgagggtc gaatccttta ccttctttat ctttaccagc ttcgatatat
      181 ttacgagtag ctgcagcaaa tgataattgg aattcagtgt taacatttac ttttgagata
      241 cccattgaga tagctttttc gatttgatct tgaggaatac ctgatccgcc atgtaatact
      301 aaaggcatgt ctggacctac agcatcagca attgcttgta agtggtcaaa agctaatcct
      361 ttccagtttt ctggatattg accatggatg ttaccgatac cgcaagctaa gtagtcgata
      421 cctgtagcaa ccatttgttt gcattcttca atatcagcta attcgccgtt accgatgatt
      481 ccgtcttctt ctccgccgat tgaaccaact tcacattcaa ctgagatacc ttttgcatgt
      541 gctttttcaa caacgtcttt agctaatttc aagttttctt caaatggtag atgtgaacca
      601 tcgaacatta ctgaagtata gcctaattcg atacattcca aagcagcttc gtaatcacca
      661 tggtctaagt ggatagcaac tggaacagtg atgttcattg cttcaactaa atcagtgatt
      721 aaatctttac agattttgta accacccatg tatttagctg cacccattga tgtttggata
      781 agtactggtg cttgttttgc ttcagccgct tcaaggattg cttgagtcca ttccaagttg
      841 tttgtgttga atccgccgac agcgtaaccg cctttacgag cagcttttaa aaattcagct
      901 cctgatacta ctggcataat aaaattcctc ctaagttttg taaaactaaa tttgttaaga
      961 caattcttaa ccaacgaccc tattttacca aacatttcgg tagttttcta ctaaaatcaa
     1021 tgaaaatgaa aattttcaag aagttttttg caaaaaataa aatatccaat agcgctttaa
     1081 tcgaaaaaag tcttttgctt tctatctttt ttcctacaaa taataacaaa tcagaaaaag
     1141 agaaaagtga caagaaaatt gcttatcccc ttctcttgct acttttctct ttctatcaag
     1201 ttcaaaaatt attttgtttc gtgatctgct aatgatgctc cgacaaatgc tttgattaat
     1261 ttttgcgggc gatttggacg agaaatcaat tctgggtgga attggcatcc cacaaagaat
     1321 tttttctctg gcagctctac gatttctact aaacggttat ctggtgagac acctgaaaag
     1381 actagccctt gttcttcaaa caattgacga tatttgttat tgaactcata gcggtgacgg
     1441 tgacgttctt gcacaacatc ggctccatca tatgcttcag ccgtcttcgt tccttttttg
     1501 attttacatg ggtataatcc aaggcgtaaa gttccaccca aattctcgat gttttcctga
     1561 tcagccatta aatcaataat attgtttgct gtatctggat tcgtttcagc tgatgacgca
     1621 tcttctaatc caacgacgtt acgtgcaaat tcgacacaag ccatctgcat accaagacaa
     1681 atacctaaaa acggaacgtc attttcgcga gcataacgaa tcgcttcgat tttcccttct
     1741 actccgcgat caccaaatcc accaggaacc aagattccat ctgcgtcttt caaacgttct
     1801 tctacatttt ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat gtctgaatta
     1861 taggcgaaac cagaatgttt caatgcttca actactgaga tatatgcatc tggtaactcg
     1921 acatatttac cgacaagcgc aatccgtact tttttcttca agttcaagac acgttcttct
     1981 aattctttcc attctgtcat gtctgcttct ggtgtatcta gttttaaatg gtcgcaaaca
     2041 atttgatcca ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt atctacatct
     2101 ggcgactcga taactgcttc tggttcgaca tcacaaaatt gtgccaattt gtttttcacg
     2161 ctttgagaaa caggttgctc tgtacgtacc accaaaatat tcggttggat acctaaacca
     2221 cgtagctctt ttacactgtg ctgcgttggt ttagttttca tttctccagc agctttcaag
     2281 taaggaatca atgttgtatg gatatacata acattatctg taccgacatc tgctttcatt
     2341 tgacgaagtg cttcaaggaa tggcaaagat tctatatccc ctactgttcc ccctacttct
     2401 gtaatgatca catctgaatc agtcatttta gctgctcgca tgattttttc tttgatctca
     2461 tttgtaatat gaggaataac ttgaacagtt gctcccaagt attcgccctt acgttcttta
     2521 cgcaaaactt cagaatagat ttttcctgtc gtcacgttgg agtatttgtt caaattgatg
     2581 tcaataaaac gttcgtagtg gcccagatcc aaatctgttt cagcaccatc atctgttacg
     2641 aatacttctc cgtgctgata tgggctcatc gtccccggat ccacgttgat gtatggatca
     2701 aatttttgga tagttacttt taagccgcgg tttttcaata agcgtcctaa agaagctgca
     2761 acaatccctt ttccgattga tgaaacgaca ccgccggtca caaaaatata ttttgtcata
     2821 agttcaaaaa ctccttttta atttatgtgc aggaaaagtc tcagacaata aacaaagctc
     2881 cctattcttc aataagaata gggagccgaa atttctgtaa acttctgacc ctctaaaagg
     2941 gtgcccaagg tgtataatac aagctgacta agggaaagtc aagtactcaa atgaatacta
     3001 tccgcttaca attttttctt tttcgatatc ctttgagaaa ttatttctta agtcctttat
     3061 gagtgcaaaa aaaatttaac ccacataata agcttgatat aaacatagct aacgttaaac
     3121 ctaagcaaat cagaaaatcg ttactgaaaa attttaagtg aaataataga taaaaaaata
     3181 aaacaaacat tatgatagat aatatcccac ctaacaaaga actacttttt cctacttgca
     3241 gcaacagttt atatagctta tcgtagaaac aatctttttc tttcaccctt atttacctcc
     3301 tttacgtaaa aaacgtagtc cacagttctc ggatttttgg catatctttt ctattaaata
     3361 atatcaaaaa caaaacaatt ccactaattt tttcaaagat gacctttttt tcaacaaaag
     3421 tgccttgtag ggattcattg aaggtaacga atcacataag taaaaaataa ggagatgcga
     3481 caaaagtcgt gcctccttat ttctaaataa acggtgttct cctgccaact cctcggtcac
     3541 aagtcacaat atccatcaaa catgagaagc tgtttttgaa attatttctt gtgattcgga
     3601 gttaaatggt aggctcacaa cctctggata aacggtattc aaaagccagt ttctcggtat
     3661 taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttaatactcg
     3721 aaactaaacg tctttttcaa aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
     3781 taataagttc agccaattca aaaacaagaa aagctgtttt tgcttggcta ttcttattac
     3841 ttgttgcagg gcagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct
     3901 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt tttccgttag tttctctaat
     3961 actcaggtca aaacgctgat ttcacagcct ctaattcacg gtattcctgt tttaataaag
     4021 ttctagatat tgttctcttt cccactcgga aacagtttgt ctgaatgccg cccattcgag
     4081 acgttttgct tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa tcattacatt
     4141 atccttacgc aattctttga tagcattatg gatagttgaa ggtaagtcct ggatatgtgc
     4201 agcttctctt tcttcctcat ccattacata aatgttacgg tcaacagctg ctggcggtgt
     4261 gatctgatta cggataccgt ctagtcctgc ttgcaacaat actgccattg ccaagtatgg
     4321 gtttgcagat ggatcaactg accgcaattc caaacgtgtg gataaaccgc gagattctgg
     4381 tacacgtact aatggcgaac gattacggcc actccatgcg acataaacag gcgcttcata
     4441 acctggaacg agacgtttat aagaattgac tgttggattg caaacggctg tgtaggcacg
     4501 agcatgtttc agcaaaccac ctaagaaatg ataagctgtt tcacttagtt ccaattcacc
     4561 gtctttatca tagaaaacat ttccttcatc attgaacaaa gacatattgc aatgcatacc
     4621 agaaccattg atcccaaata acggtttcgg catgaaagtc gcgtgaagtc catgcttgcg
     4681 tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta tcacaagcat ctaccacatc
     4741 tgcatattta aagtcaattt catgctgtcc tggcgctact tcatgatgtg aagcttccac
     4801 ttcaaagcct agactttcta attccaacac gatgtcacgg cggcaatttt cacctaaatc
     4861 tgttggtgca aaatcaaaat aaccaccttt atcattcaag gtcgttgtga tcccaccgtc
     4921 ttcgtctaat ttaaataaga agaattctgg ttcaggtcct aaattgaaag aggtaaaacc
     4981 aaggtcgcgc atatctttca atgctcgttt caaattcccg cgaggatcgc cggcaaatgg
     5041 tgtcccatcc ggattataga tatcacaaat taaacgagca acttttccat gagcactttc
     5101 ccacgggaag atcatccaag tggagagatc tggatacaaa tacatatcgc tttcttcaat
     5161 tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt ttattttcta atactttgtc
     5221 gatctggctc actggaactt ctacattttt gatcgtacct aagatgtctg tgaacatcaa
     5281 tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg atttcttcac ctgttatctg
     5341 tttctttacc atggtatccc tcttcctttt ttaatttatt cagtcaaaga attgtctttg
     5401 caatccttgc gactgataat gacctgtttt gcttaaccca ccttgcgcca aaatctcatc
     5461 acgaaaaatt tgtcgaacgt catgatctgt caacggcttc ttgttttttg cttcttgttt
     5521 tttcgcctgt gccatttcgt atacacgttt gatcccagcc atattcaatc cctctgaaag
     5581 atagtcttta atctcaagca acatatcaat atcattcagc gaatacatac gtcggtttcc
     5641 ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa tagcgaattt gccgagcaga
     5701 caaatcagtc agcttcataa ctgtaccaat tggaaatacg gacatagatc ggcgcaattc
     5761 cttttctccc atcagacgtc ccctttcgtt ttataagttg gctaaagtgt accaattaaa
     5821 aaaaatattg tcaactgcat atgttaggtt ttctaacatg agatctctat tttttataaa
     5881 ataacaaaaa aataagaaca caaaaaaggt atctagttga ttttcgtacc agataccttt
     5941 tattttttat tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DAIGQM010000099         5856 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.103, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000099 DAIGQM010000000
VERSION     DAIGQM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.103"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOA48_002534"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOA48_002534"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCI0790762.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="NOA48_002535"
     CDS             complement(1172..1867)
                     /locus_tag="NOA48_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCI0790763.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="NOA48_002536"
     CDS             complement(1880..2596)
                     /locus_tag="NOA48_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCI0790764.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="NOA48_002537"
     CDS             2926..3531
                     /locus_tag="NOA48_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCI0790765.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLCEHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="NOA48_002538"
     CDS             3856..4179
                     /locus_tag="NOA48_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI0790766.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="NOA48_002539"
     CDS             4361..5731
                     /locus_tag="NOA48_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCI0790767.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT         1665 a         1154 c         1096 g         1941 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gtgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttt
//
LOCUS       DAIGQM010000100         5466 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.104, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000100 DAIGQM010000000
VERSION     DAIGQM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.104"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            118..1107
                     /locus_tag="NOA48_002540"
     CDS             118..1107
                     /locus_tag="NOA48_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0790768.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="NOA48_002541"
     CDS             1089..1550
                     /locus_tag="NOA48_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0790769.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLVLMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="NOA48_002542"
     CDS             1600..2064
                     /locus_tag="NOA48_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0790770.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="NOA48_002543"
     CDS             2078..2827
                     /locus_tag="NOA48_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790771.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="NOA48_002544"
     CDS             2827..3657
                     /locus_tag="NOA48_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0790772.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="NOA48_002545"
     CDS             3657..4304
                     /locus_tag="NOA48_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0790773.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="NOA48_002546"
     CDS             complement(4402..5178)
                     /locus_tag="NOA48_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0790774.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="NOA48_002547"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="NOA48_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1871 a          739 c          974 g         1882 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattagtttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttat
//
LOCUS       DAIGQM010000101         5413 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.105, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000101 DAIGQM010000000
VERSION     DAIGQM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.105"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(151..426)
                     /locus_tag="NOA48_002548"
     CDS             complement(151..426)
                     /locus_tag="NOA48_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HCI0790775.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(398..1351)
                     /locus_tag="NOA48_002549"
     CDS             complement(398..1351)
                     /locus_tag="NOA48_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0790776.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1963..3456
                     /locus_tag="NOA48_002550"
     CDS             1963..3456
                     /locus_tag="NOA48_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HCI0790777.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3591..3887
                     /locus_tag="NOA48_002551"
     CDS             3591..3887
                     /locus_tag="NOA48_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0790778.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3988..4839
                     /locus_tag="NOA48_002552"
     CDS             3988..4839
                     /locus_tag="NOA48_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790779.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4860..5143
                     /locus_tag="NOA48_002553"
                     /pseudo
     CDS             4860..5143
                     /locus_tag="NOA48_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1863 a          834 c         1009 g         1707 t
ORIGIN      
        1 tttagtatag taaaaactag aaacaataaa atttgtgaat gttgtatacc cccaaacaat
       61 acacatattt tgaaggatta ggattaataa agctaaaaat atagtaagta tactaaatat
      121 atttactata tctagtatac ttactatatt ttaatctttt gatcgtctat tatatataat
      181 ccgttcctcg tcgtttaaag tatcaacata ggcgtccatt gcaagtttga ctatttcata
      241 cataggaata tcttttgcat aactaagatc ccgaatggtt tttagtacgg gaggatctac
      301 ttgaactggt tttctttctt tcgcagtgta ctttcgttcc cctaactcga cattaatatc
      361 atctttaatt gaaatatctt cagcaccaat tttcttctta tctttgttcg ttggtaataa
      421 tgccatttag tttaatctcc tttccaagag gtaggatatg attggccatt gagtcagcat
      481 atttaggtgt ataatcaaat ccttcaatat caccatgttg ttcatagtat tcaattcttt
      541 cttctaattc tgtaaagatg tctgcaaaaa tagcccacca tcttcgatct acataatcat
      601 ttaattggat accattctca ccatacattt ctaaccgatc cgagccttta acaatgcttt
      661 taaaaatgtt tgattcacca tacttatcaa ttgttttttg atagtttgcg tgttgagagg
      721 aacgtcgcac tgagaaaaga acaggcaaaa ttccaatgat ttgaagatga gactcttcaa
      781 aattcgtgac aatcggaact aaaactttat taataaaatc ttctgttcct tccattgcgt
      841 accgttttaa ttcttgcatt gcaataatat aatctgcagc agttaagaat gcacgaacca
      901 cattatctgt tgatggtggg cagtcgataa agatataatc gaaatttttt ctcaattctt
      961 ctaaaggttt aatgaaggcc aatgatctct tacgacgatc aggatatttt tcggacaagt
     1021 attcattaag ttcttcagat ccaggagagc cagccataat atataaatgt ggacttactt
     1081 gagtaatacc tgaaacccag tccccttttt tgattgctgc agacatggat cgatcaaagc
     1141 tagtaatttg atacgttgat ccaatgttgg aagtagtatt tctttgttgg tcataatcaa
     1201 ttagcaacac gtctttttca aaaagttgac tagaaacaat cgctaataaa tcattgtctg
     1261 tagtcttacc aatgccgcct tttctacctg taagcattac aacttttcct agtttatctg
     1321 atgttttaaa tgcagtccgt aagttttcca tagttccctc caatttccta tactaaatat
     1381 atttagtata cttcatatac ttaatatatt cgatatatct aatatactcc aaattgataa
     1441 gaattcagac tttataagga atatagtgga tatactaaat atatttgcta tattcagtat
     1501 atcagatata ttcaaaatgt caaaatatat ttgtgcgttt tgcgttgaca atttagagtg
     1561 aaaagaggta aacttaattc tatagaaacc acagataatt cactatttac aaagtagcaa
     1621 aagcagtggt actctttaaa cagaaaaatt acataaaaaa aagagacgga aataattgat
     1681 tttagcagaa tcaattattt ctgaatcaca tggttaggac atgtgttcac gctcgtctca
     1741 agaatatgta agtagctacc aactacttat attaaaagtt gatcggatac cttttccgat
     1801 tgcctttatt ctaccaaaaa aaggcgagca actcaacaga agaaagttta tttagtgtac
     1861 ttaaattaaa tattcttaaa cactgaagag agaacacata ctatggctga gattaaagct
     1921 aaactgtgtt ctctttttgt ttgagaaagg acgttacaat cgatgttgag cgaaatttat
     1981 tcagctattc ttaaaaacgg cttacgtaca tacaaatatc gaaacagcac catgaaacct
     2041 gcaggtcata ttgattccag taggagtggt gctatctttg cgtaccgtag caagcaatta
     2101 atgaatgttg ggcgtggtat ggtcattact tcggaagaag ctattttaga gaacgaaaag
     2161 aaactaacgc attggacacc taatacctat cgctttggta cttatgcgga tgattatcga
     2221 acagtggtta aaggtcattc tgagaaaaac ttaagtcaaa tcaacacatt tgtagttgat
     2281 atcgattcaa aagagaacca tcaaggcgaa attattttag cctgtttaga tcaagtgggc
     2341 tacatgccaa cgctaatttt agaatcagat catggttatc aagtttattt tgtactaaag
     2401 acaccaggct atgtcacaaa gaaaagcaat ttcaaggtga tcgatgtagc aaaaaaaatt
     2461 tcaaaaacaa ttcgtctaca gttggctgaa aaattgtccg gagtggatct aggatgtaac
     2521 cacttcggaa ttgctcgatt cccacaagaa aataatattg tttttaaaga aatgaactat
     2581 cagtattctt ttgctgactg gattcaatgg tcgatgaagc ttgaatcaga tcaaaaaaca
     2641 aaagaagatc gagaacgaaa actaattgtc tttcctgaga aaaaagaaat tcgtcaagta
     2701 gatgaaccgt ggttcgatat gttacttcat aaagcaaaca tcgtcggcgg agaaggacgt
     2761 cttggtcgaa ataatgtgat tttcacgctt tctttagctt attactcttc aggttatgca
     2821 ttggatactt gcgaatacaa tatgttcaca ttcaacgaac ggttacagga accgctatct
     2881 gaagcagaat tagtaaagat tgtacgtagt gcttattctg gtaattatca agcagcaagc
     2941 agagaattca ttattgaatt gtgccagcaa tgggtttcac caaccttaaa aaataatgat
     3001 ctgttcattc aacgacgtgg ctggtggaaa tttaaaaagc cacgagatca aagaaaatat
     3061 agtcataaaa atgaatggaa agaagatcta ttggcttatc taagcgaaaa aagtcttgct
     3121 agtgagcctt atttgaacct gtcaaaaaaa gaattggctt cacaactaac gatgcccaag
     3181 cgaacacttg ataagatctt aaatgagtta cgagaggaga ataaagtctt ctacaaggta
     3241 acacgaggaa gaaatggcgg aatgatcatt gcttcagtca aaacgttgtt cgcgagggtt
     3301 attcaactaa gtaaagaaaa gagactagat tattcaacaa ggatcacaga ggtatttgga
     3361 ctcaacgaga gcttagtaga agagacattt agacaattat caaccccctt gaaccctctt
     3421 aaagaagtga atctttttga agtagataca ggttgaaaaa taaaaggtgc aaattgccct
     3481 atacaatata tctatgatac ttctgtaggt gttgctccct ttgcctagct acgtgtaggt
     3541 ggtatactta taactgcgta tgcagtctta tgtatcatgg aggaagttgt atgtcgttaa
     3601 aaaattatgt ctattcacat cctgttaatg tgtttatcat tggtcgtttg ggattatctg
     3661 tggaagtgtt ctgtgagctt tatggtttta agcaggggac tttgtcttct tgggttacca
     3721 gggaaaaaac agttgcttct ttgccgattg agtttcttca tgggttgtcc ttagcttctg
     3781 gggagactat ggatcaggta tatgattgtt tgtgtgtgtt agagcaggag tatattgagt
     3841 ataaaatagc taacgagtta agaaaaagga agaagtatat ccagtagtag tttttattta
     3901 cttaaaaaat tggttcattg agcaacctat cgctgctaaa gtagcaaagg aaaacgttaa
     3961 aggaaagaat ttagggaaga aatcgaaatg aaatcggacg actggattga acacacctgg
     4021 cttcctctga aaagaaatag caaacgaaag aaattttggg tattgcaatt atggccatta
     4081 ggaaaacttt gtagttacgg ggcacgactt attcttgatt taaccgttta ctcgattgga
     4141 gtatttggaa cggcttatta cttgataaat gatcccaata ggattgcagc atcagacatt
     4201 tttacagtgc taatgacgtt gatttttgtc atgctattgt ctatttttac tcaattagtc
     4261 atgcaattta ccaggcaaaa attaacagca ggaaaacttt tcaaaagcct attcgattta
     4321 attgttgtaa atgcaattct agcgacttta ataaaacaaa ttgaacaatc tggaagaaca
     4381 acaaaaggag tgaaggattt tttattgacg tttattcact ttgtaaatgg acacatgtat
     4441 ttgtttgaag tgggtattat tctctttttt gtcgggtatg tatccacgaa acttattaaa
     4501 cgttcaattg aaaaagaaat tgaaattgac ctgattccga cacttcttgg ttatgagtac
     4561 aatgttgatt ttggaagata tgacgaattg atcaatacgg atatcgttca cacgagtatc
     4621 catgaatcta ctgttaaggg catcagatct attttaaaaa atggccagga aatgaaagca
     4681 atagatcgaa gaaaagagat ctacaatttt tatgaagtcg aagcaagcct acgatatggc
     4741 atcggaaaat tgtggttaga tggaagtaat attcgtcaaa acaaaccata cattttttgg
     4801 aacagtagtg atttagaact tccaatgaaa gataaataat tatggagaat cgtttgaaaa
     4861 tgattcctct atacaggatt gtgcttatag ttggcatgga gttaaaaacc ttaaagaagg
     4921 agcagttatt caaagtgaaa gaacgtcata atcagttact atgtagtaaa acgggtacga
     4981 tgaacattga ataccgaaca gaatatttag aattaacgaa tcaaactgat tttttgttga
     5041 ttcgaaagca acaagagcaa gaaaaaaatt aatggctact tatagccaat tgattgatga
     5101 atgggaacaa ttcaaggaat ctaaaattcc agaacgtctc taaaagcctt tatttgtaaa
     5161 gagcataagg aaacgtggga acacttttta aaaaaagtgt tccaataggc tgtgcctatt
     5221 acgtttctca aaaataaatg tgggaacaaa atatttaaaa ataggatagt gaaaggatag
     5281 tgaaggatag taaaaggagg gtagtaggat agcaaaaagg ataggctcct tttcgctatc
     5341 ctttttaaat tggaggaatt aatatggaag taagaataag aaatgtggat gagaaaatcg
     5401 taagagaaat tga
//
LOCUS       DAIGQM010000102         5312 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.107, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000102 DAIGQM010000000
VERSION     DAIGQM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.107"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(96..698)
                     /locus_tag="NOA48_002554"
     CDS             complement(96..698)
                     /locus_tag="NOA48_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0790780.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            821..1021
                     /locus_tag="NOA48_002555"
     CDS             821..1021
                     /locus_tag="NOA48_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790781.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            1033..1359
                     /locus_tag="NOA48_002556"
     CDS             1033..1359
                     /locus_tag="NOA48_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790782.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            1512..2564
                     /locus_tag="NOA48_002557"
     CDS             1512..2564
                     /locus_tag="NOA48_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0790783.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            2640..2858
                     /locus_tag="NOA48_002558"
     CDS             2640..2858
                     /locus_tag="NOA48_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790784.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2845..>5312
                     /locus_tag="NOA48_002559"
     CDS             2845..>5312
                     /locus_tag="NOA48_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790785.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKIN"
BASE COUNT         2025 a          701 c          986 g         1600 t
ORIGIN      
        1 tatcgtgcac cgctttttgt tgtgtacttt tgtattgaca taactaatct ctccaatctg
       61 ataacttggc gagttggctg attgaataat tagttttatt gaagttttga tattaatcga
      121 gctgttatct ctctttttag attgttaacc tgtacttggg ttaagttgcc aaataactca
      181 gattctaact cttttctttc atcgatattt aagtttaaag ctttattaat aaacttcttt
      241 tgtttggcaa atagaatcgt gtattcaaag gagtcctcta gaatactttt taaaaaaaga
      301 aagtcggagt catcttcttg aagtttgact tcaagtaaag aagtcatgga aaagtataga
      361 ttagataatt cagtaaaata atctgagtca agactggcaa tattcttgac tattttgtcc
      421 tttttttcta aacgagcagt ttttattcta tcaagattag gttgttctat ggaatttgtt
      481 tcgtctaatc ccatcaaata acttacagga acatggaaat aatcagcaag gatattccat
      541 gtttcagtat ttctaggatt tcgctcacca cggtaatagt tcgtaagagt tgtatagtta
      601 ataccagttt ctgtactaat ttgtttaatg gtctttttac tggaatcaat ataaaatttt
      661 attctattca aagtaacgcc ccctatagta aattccaaac tattatagca tgaaaaccac
      721 aaattgagta atattttaat tgatattact cgttttgtgg tttaaaatgt gcttattaag
      781 ataaaaacca caaagtgaat aatttgaaag gaggcgctga atgataactc ttaatgatca
      841 attcattaga agcttaagaa gacatagagc cgatcttata cttactaaaa acgatgcagc
      901 aaaattgata ggtataaatc ggaaaacata tgtcaaaatc gaaaatggga gcaaagaaag
      961 tattagagca tctacttatc aaaagttggt aaattggtta cttaatgatt tgaaaatcta
     1021 aataaataca acttggcgag ttggctgatt gaagaaatag aaaatgagag gagaaaaata
     1081 atggatgcag gaattacagt aatgttagat aaacaacaaa cgaatcaatt gaaaaattat
     1141 gtttttgaaa tgacaaaaga ggctattgat caagcaagaa ttgataccgg attagaaaga
     1201 ccatttctaa aaggaaaaga gatggctaaa tatttgaatg tatcatatac aacttttttg
     1261 aaatttaaaa gaatgggatt gccagttatt ttattagaaa aaatggagtt gttttcaaaa
     1321 gaagaatgca aaaaatggat attgagtcat caaatttaaa aaacacctcg ttttttaaat
     1381 ttgatgaagt agaaaaaatt aaaaagagtg ttcccgtcag tttgcagatc gggggaacac
     1441 tcaataataa agttctgaga aaactttatt tgaatctatt atagcaaata aaatcagaag
     1501 caggtgtgac aatgaatgaa aaagaagttg aaagcttagt tgaaaagcaa ggctattcta
     1561 attctgatat atatgcagaa ttatactatc aatatcctat ttttttaaac gtaaatgaaa
     1621 aatataagaa aatgaaacta agttctaagt tagtttatat gttactaaaa gatagaaata
     1681 gactttcatt gaaaaataac ttgtatgatg agaatcaaaa aatttttttg atatttgaaa
     1741 tcaaaaatct cgtagaaatt tcgggaatgt caaaaaatac aatcttatca gcactagatg
     1801 aacttcaaaa agttaaactt cttgtgaaaa gaaaaaatgg cttcaataaa agtaaaatgc
     1861 aaatgttccc aaatttttat tatttgttaa agcctgttct gtgcaaagat gatgtttata
     1921 aaattaataa gataacccat caagaaaata gacaaaaaaa cttgatagtt caaaatttga
     1981 actatggaac aaatcaatat tctgttgata attcaaaatt tgaactatgc gacacatcaa
     2041 tgaaaacaag agacaaaaac aattttgctg atagttcaaa aaatgaacta gaattatata
     2101 agtcttataa agatagtaaa gatattaaag aatcacataa tgatgatctt cttgaatcac
     2161 tttcaactaa aaataataaa ttagatgaag aattgatcga aacatttatt gaagaaaatc
     2221 ttcttaaaca aatatgggga gaaagtattg tgaattgctt aaaactggct agcaatagtg
     2281 attatcgtca attcgacaac tggtacaaaa aattcaaata tgcgattaga tctgctgaaa
     2341 aagaacaaaa aattcaactg aaaattatct atgaaatttg taataacaag tattttgtag
     2401 atcatgttag agaacagcta tcaatgactt tacgtgactt gatacgaaga gcaaaaacag
     2461 atcatcgtat caaacaaaaa gacgattata tctttgcttc tctaaaaaat aaagcgttag
     2521 aactaattga attgcaaatc agcgaaggaa tagataagca ataagaatag aattgagtca
     2581 aatgaaatgg aggggtatct ccacttcatt tgagaacttt gaatatagga ggggttattt
     2641 tgattaaaaa tcgtttaata gatcaagttt ggtgtctaga tcaaaataca gatagtctcg
     2701 aattaatcga gactatttgc ttcaacacta tagttctcga tttaagagct gaaaatgata
     2761 attgtgtaac tcatgtcata attaatcaaa aaatggctca gaagctctct gagagcctca
     2821 gaaaatgggc taagggaggt aacgatgaaa ataattgaaa aaaagattgc caataaaaaa
     2881 ataaattggt tggttgttaa ttttcttgtt ctgatagcta tgattatttt tacaagtaat
     2941 attgctcatg cgagtatttt caattggttt gatgacacaa aaagtcaaac agagtttttg
     3001 aataattctc tttatagacc ttacctaaaa aagtacaatg gagatttcct tagtcagttc
     3061 gggatttggc tcggatgggc tgtggtaaaa ggcatgttta ctgtgacaga ttcgattcaa
     3121 aatatgattc cagatgtgct ggatttgttc aatttcattg aaagtacagg gctaaataat
     3181 gtttatcaat cagccgtaaa tacaattgtc attggattaa tgatcctttc attgatgttt
     3241 gttggttaca aaatgattac tggaaaagga acagtggatt taaaatcggt tggaatgaac
     3301 gtagtgatgt ctatagcatt aatactttta atgccaacca tgatttctag tggtattcaa
     3361 tttgctaaaa cattttataa ggactctact acgattacaa attcagatga cggagtcgct
     3421 tggtcattga taaaacaagg agtaacagat ttagcatata ttaataaaac agatcagtac
     3481 tcaagcattg ataaaacgga ggatcgaaat aatttaacac gaaaaaattt tcaacagacg
     3541 gatctcacac aagtgttaac ggataaagtg attgataaat tggaaaaaga aaatccaatt
     3601 gcggacaatc ttcgttatga attagttgaa aattctaata atgaatttgt tgctacaaag
     3661 ttttctgaca acttcttatc aacattttct gatagcttga aatcaggcta ttaccgatac
     3721 caagcaaatc tatgggggat ttcaattggg ttgacagcgt tagcaatcgc ctatgtgttc
     3781 agcgcgtttg tgatcattac agcaatacta gaacttgcat ttaaacgtgt gttaggtgtt
     3841 cttgtttttg caacagatat tgagacagga cagcgttcaa aagttgttct atcagatatt
     3901 ctacaatgtt acttaactgt tgggtttcaa ggatttgggt tatcaatgtt tgctatgttt
     3961 atcaattttc tgaactcagg acaaggtatc tcaacaaata tttttataaa aacaattgct
     4021 tatatctgtg ccgtttttgt tttaatcaaa ggcagtggaa cagtcatgag atactttggt
     4081 gttgatattg gactcaaaga aggctatggg caacttgctt ctgcttttgg aatgggcgca
     4141 atgctgttta gaaaaggatc aaatggattt aatcgtgcta aaggaagcgg agaaggagaa
     4201 gatcgaaaac cagaaaagaa tttcggcgaa actctatcaa aaaaagctgg caaaactgga
     4261 agagctttgg gatatgccca tgaacgtgga ttatccggtt tagcttcaga tggagctaca
     4321 atggctagtg aaagagcaac aaaaccattt aagagtatgc gtgatatagc taatgatacc
     4381 aagaataagt ttaaagaagg tttagatgat ggtacagtgt ccgctattaa taaaaatagc
     4441 aaacctatgt tagctaaaaa taaagaagat gaaactggaa aatatgctga ttccgtgcca
     4501 acacgtcttt cagatagaaa agatggtgct aaagttgaaa atgccgatag aattatgtct
     4561 agttctgaac gtatgcgtga agcaatgaaa aataatgctg aatcgaataa taatcctgca
     4621 agcgcaattc agcaaaaagt ccaacaagat attgaagaac gtaaaaatgc tatgcacggt
     4681 caagctaagt ctgctgaaga attaattaat cagaagcgtc atgaagcgaa atacacgcct
     4741 gaagcaatga atcgcgagga aataatgtta aggaaacgtg tagaagggcg gacaggcgct
     4801 aatattgacg gaaaagaagc gttgaccaaa gaaagaattc aagaagctaa aaattcaaat
     4861 acaggattag aaaaattagt caaagaaaat ccacaaaatt ctacaagtag tcatggtggc
     4921 cgatcagtag atgtccgaga aaatattcaa ggttcactga atggtcatgt tggacggaat
     4981 gttgatgtaa gagagaattt acaaagttct tcaaatgctc aaggtactaa gacaattgat
     5041 gttcgagaaa atctgcaaag tagcagtaca agtcaaccaa aaacagtaga tgttcgagaa
     5101 aatgtacaaa attctacaag tagtcaaggg tttaaatcag tggatgtccg agagaatgtg
     5161 caaggtagca gtgcaagtca accaaaaaca gtagatgtcc gagaaaatgt acaaagttct
     5221 acaagtagtc aaggattcaa aacagtagat gttcgggaga acattcaaaa agatagtgga
     5281 gaaatgaaag aaaaaacaca aaaaatcaat at
//
LOCUS       DAIGQM010000103         5197 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.108, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000103 DAIGQM010000000
VERSION     DAIGQM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.108"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            21..692
                     /locus_tag="NOA48_002560"
     CDS             21..692
                     /locus_tag="NOA48_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0790786.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            751..1191
                     /locus_tag="NOA48_002561"
     CDS             751..1191
                     /locus_tag="NOA48_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790787.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1203..1871
                     /locus_tag="NOA48_002562"
     CDS             1203..1871
                     /locus_tag="NOA48_002562"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0790788.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1935..2558
                     /locus_tag="NOA48_002563"
     CDS             1935..2558
                     /locus_tag="NOA48_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCI0790789.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2614..3000
                     /locus_tag="NOA48_002564"
     CDS             2614..3000
                     /locus_tag="NOA48_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCI0790790.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3213..4604
                     /locus_tag="NOA48_002565"
     CDS             3213..4604
                     /locus_tag="NOA48_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCI0790791.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1727 a          861 c         1094 g         1515 t
ORIGIN      
        1 atgaaaaaag ggggagaaaa atgaattttt tagttgtttt aaaagatact ctgattgagc
       61 gatctacatt tctatatgtt caattgcagg aaaataaaac attgctgcat ttttcaccag
      121 agttccatct agaggggcta acattaggag aaatctatca agcagaaggg ctgtcggctg
      181 ttttgcactt ttttaaggta gaattggaat taccagtaaa agattatatc gagctttctc
      241 ttgaatcttg ggatcgagca gtggttgaac tgtttccaga aggtttaatg atcgatacaa
      301 acgatgggaa gatccatctg actgcagcag aactgcaaaa acaaatgcgt tatcaaatag
      361 atgacgaaaa ttctttttct atttttagac gtcagcaaaa gattctaaaa agctttttaa
      421 aagtgatcag taaaaaacgg aatctgatca aaacgacaca gctgttgaaa aaatatccag
      481 gtctgcttca cacgtctatt caatttcctc aattgattac gatgatccat cgttttatac
      541 gtatgcaaca gctaccatct aagaagctgt ttcttccatt gacggacaca tttcgagtag
      601 tcaacagaga agataaaaag aaagtgattg tgattgactt taccagaaat cggaatgtcc
      661 ttcaccaagt tgcaatggaa aaggccaatt aaggcttttt ctttttggat ttttttgtca
      721 taataaatat tagatgatgg aggagataat atgatgcaaa catggttaga aaggctaata
      781 cgatttcagc agaactatca caaacttatg cagggaagat atgcgaaatt tgatcagttg
      841 aatcgcggtc tattgatcgc tgcgcttgtc tttagtttgc taagtcgttg gttgccctat
      901 agaatcggac aattgttgtt catcgtcttt ttcggatgga tgatatttcg tttcctatca
      961 aaaaaaatct accccagact aaatgagaat caacgttatt tgaaatatct tgatagagtc
     1021 aaagaaaaat atcatcagat aaaaaacaaa aagcaagtca aaatggatcg aaaaagttat
     1081 actttttttg agtgcccgaa ttgtcatcaa aagcagcgtg cacctaaagg aaaaggacga
     1141 atacgtgtga catgcaaaac atgtggtata aaattcgaaa cgaatgttta agggagaaaa
     1201 gaatgaaatt agtattatta cgtcatggcg aaagcgaagc aaattttgaa aattactgga
     1261 caggatggct agatgtcgcc ttaacagaaa aaggaaaaga acaagcagca gttgccggtc
     1321 aaaaaatgct tgaagccgga cttcaattcg atgccgttta tacctctgtt ttgaaacgtg
     1381 cgattcttac cggacaagtc gcactagaag aaatgggtca gttatggctt cctataataa
     1441 aaacatggcg tctaaatgaa cggcattatg gggatcttgt gggtaaaaac aaagataaga
     1501 tgaaagaaat atacggaaaa gatcaagtaa aaacatggcg cagaggatat acggaagttc
     1561 cgccgttaac cgcagaaaat agatttgacc gcagatatga tcacttggat ccgcatttga
     1621 tcccatacgg agaaagtctg gaaatgacag tgaatcggat cattccctta tggcaagatc
     1681 atctagcacc aaaactaaaa gatcggcaag atttactagt tgtgggtcat ggtaatagca
     1741 tccgagcact gacaaaatat ttagaagatg ttcctgaaga tcaaatggat acgatcgata
     1801 tcccaaatgc acaaccaatc cagtatacat tagcagatga tttgacaatt ctggacaaaa
     1861 aaatacttta aagaacacct ttatctaaaa gtgagagata gaaaaaagaa gcaaaggaat
     1921 ggaacaaaag gaacatgaaa aattatatat gggactttga tggtacattg tttgatacgt
     1981 atcccgcaat ggtagatggt gcatggcaag cactaaaaga ttttggtatc agtatggaca
     2041 aaaaagaaat ctacttcaaa atgaaaaagt attctactag ttatttgatc aatgaatcaa
     2101 acttgaatgc cagagagttt aatgaattat ttcaccgata tgaaaaagaa agtacggaag
     2161 tttcccgtcc atttccagaa acgaaacaag tactggaaat gctaaaagac aacggcggtc
     2221 gtcatttcat cctgacccac cgtttgacag aatcaacatg gggcctgtta aaagaacatc
     2281 gattggcaca tctgattgag gaagtagtag ggatcgatca ggactttcct cgtaaacctg
     2341 atccagcatc tttaaattat ttgatcgata cttttcattt agaaagaaca gacacgatga
     2401 tgatcggcga tcgtcgttta gatatcgaag cagggaaaaa tgcaggagtc gctacttgtc
     2461 tttacgacat cgatcatttt ctgggtgaga tcccggcaga ttatgtggta ggaaatctga
     2521 atgaaatcct taccttgcag agcatcatta aaaagtagta tcccctttca aaggagatat
     2581 gttataattt tcataaagga gtgataaaat tatatggaaa tcagaagaca aaaagaagtt
     2641 gtagaagcat ttcattatga tatgagattg ccgaaccaag aagtagaaac agatttgaaa
     2701 gtaggcttct cgcctttaaa agaaacgatc gaaaactatc cgaaagaaca tagcatcgta
     2761 ggagcacgct tagagttccg tttagtgttt gatacatatg ttttatctgg aagtgtgagt
     2821 cagatcaatc atatcctcaa tcggaaaatt gaaggtcaaa atgatgtcac acaagaagaa
     2881 gtggacgagc tagtagcacc gttattcgat atcgtacgcc gaatgtctta tgaggtgaca
     2941 gagatcgcct tagatcagcc tggggtaaaa ttgaattttc aatcagaaaa acaagaatag
     3001 acagtaaaaa catacctgcg atagattaaa gctatcacag gtatgttttt ttattactaa
     3061 ttgtaagcaa aaagaatgtc atttcgataa aaatcgtcta aaatataaaa gtcactgaaa
     3121 aaaatttttt caggaggatg gttgaagaat cattctcggg aacctttact tccttcgatg
     3181 gacttgtcat taataatatg aggaggagaa aaatgacaac actcatcaca gttttagtgg
     3241 ttctagtttt tgcggcatta ttatatgtgt tctatcgtat gcaaaagcgc catacaaaat
     3301 tttcaacacg cgtctttaca gcattaggag ttggtatcgt ctttggcggt ctgcttcaat
     3361 tgatctttgg tgtagacgac aaagtcgtta ctcaatcaat ggaatggatc gggattgtag
     3421 gtcaaggata tgtatcattc ttgcaaatgc tagttatgcc tttagtgttt atttcgatca
     3481 ttggtgcatt cacaaaaatg aaagtttctg aaaagctagg gaaaattagt gcgactgtat
     3541 tgacttcttt acttggaaca acagctattg cagcattgat cggaattggt tcaacaatgc
     3601 tgttcggact ccaaggagct aaattcacac aaggagctgc agaaacagca cgaatctctg
     3661 aactggcaac acgtcaggaa acagttgaaa acttatcgat tccacagcag attttatcct
     3721 ttatccctaa aaacgttttt gctgatttag caggtagtcg tgcaacaagt acgattggag
     3781 tcgttatttt cgcggcattt gtcggaatcg cttatctagg cgtgaaaaga aaagcgccaa
     3841 aagaagcagc attcttttca gatttagtcg acagtctgta taaaatcatt atgcggatcg
     3901 tgacgcttgt tttgcgtttg acaccttatg gagtatttgc tttgatgaca aacgttttgg
     3961 caacaagtga ttttgcagct atcgtcaatt taggtaaatt tgtcgttgct tcttacgtag
     4021 cattgcttgc tgttttgatt gtccactcac tgattttgat tggtgcaaaa gtcaatccaa
     4081 tcaactattt caaaaaagcc tttccggtat tgagctttgc gtttacttca cgttcaagtg
     4141 ctggagcttt gccattgaat atcgagactc agacaaaagc tttaggagta gatgatgcaa
     4201 cagctaattt ctcagcaagt tttggtttgt ctattggaca aaacggctgt gctggcgttt
     4261 atccagctat gttggcaacg atcgtcgcac cagcagctgg agtgaatgtc tttagtttgg
     4321 aatttatttt gatgcttgtg gcaattgtaa caatcagttc ttttggtgta gctggagtcg
     4381 gtgggggcgc aacatttgct tcactgatcg ttttaggggc aatgaacttg ccagtagcaa
     4441 tcgttgggtt agttatctct gttgaaccat taatcgatat ggcacgtaca gcagtaaacg
     4501 tcagcggtag catggtagct ggtatcgtga caagtgcacg catcaaagat ttagatcgcg
     4561 atgtcatcaa tgatgattct aaagtgatcg atgtgaatgc atagtcaaaa agaggttgtg
     4621 atagaagtgg tcagctttaa gaaataagaa gaagtttcct aaaaatagtt tctcaaattt
     4681 ttgtgaaatt tcggcttatt tccgagaagc tacttctgaa acaccgtgaa taagaggttg
     4741 tgaaaaagct gccctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt
     4801 ttacgtttgg ttgagcttat taccgcagat gcaagctttt gaacaccgtt taagaaagag
     4861 gtcgtgagcc tgccgtttca ctctgagtca caaagagcaa tttcaaaaaa tagcttctca
     4921 tgtttgttga atattgtgtc ttgtgaccga ggagttgtca ggagaacacc gtttaccaga
     4981 ggttgtgact tgtttttagt cacgacctct ttttttattt attccatata aatacacatt
     5041 atttattccg aaaagtgaaa gcgcaaataa caaaaacaac caacttattt attattaaag
     5101 aaaagcgtat ttaagtagga cgattctgtt gagagctttc gtagattttc ccattttcct
     5161 atggtaaact gacaaagttg agaatgttag aacagat
//
LOCUS       DAIGQM010000104         5029 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.110, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000104 DAIGQM010000000
VERSION     DAIGQM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.110"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(141..1085)
                     /locus_tag="NOA48_002566"
     CDS             complement(141..1085)
                     /locus_tag="NOA48_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCI0790792.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1219..2610)
                     /locus_tag="NOA48_002567"
     CDS             complement(1219..2610)
                     /locus_tag="NOA48_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCI0790793.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2736..3146
                     /gene="tagD"
                     /locus_tag="NOA48_002568"
     CDS             2736..3146
                     /gene="tagD"
                     /locus_tag="NOA48_002568"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HCI0790794.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3322..3735
                     /locus_tag="NOA48_002569"
     CDS             3322..3735
                     /locus_tag="NOA48_002569"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790795.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3892..4149
                     /locus_tag="NOA48_002570"
     CDS             3892..4149
                     /locus_tag="NOA48_002570"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790796.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4236..>5029
                     /gene="istA"
                     /locus_tag="NOA48_002571"
     CDS             4236..>5029
                     /gene="istA"
                     /locus_tag="NOA48_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI0790797.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVN"
BASE COUNT         1746 a          908 c          791 g         1584 t
ORIGIN      
        1 agttctcttt ttcatgtaaa atatttaatt atatatttcc taaataaaaa gtaaaacaag
       61 aattaaatag ttggttatac aactttaatt cttgttttac tttttagaat tatttatcca
      121 aagatgcaat cattttttca tcaaatttct gtctttaaat accgttccat tccgctcaat
      181 atatcaaatt taggctgata gcctaaagaa cgaatttttg aaatatccgc taaggaatca
      241 cgaatatccc ctgaacgctc cgcttcatat ttaagcgcta gctctgttcc taagatttga
      301 tcaattgaat ggatcaattc aagtagcgta gtgctttttc ctgtaccgac attgaattgc
      361 tgtcctaaag ctttttcttc cttggcaaca agtaaaagtg cttgtataac atcttctata
      421 taaacaaagt ctctagactg actcccatcg ccaaataaag taaattccgc tttttctcct
      481 gccaattgtt ttttgtaacg atccactaga atcgaaatga ctccgctata tggagagttt
      541 ggattttgat ttggaccata aacgttaaaa aatcggacag cactagtcgg aacatcatat
      601 aaatgacagt aatccaaaac atattgttct gctgcaaatt tatcgatagc atatggtgtt
      661 aatggacgga tgactgattc ttcttttttt ggcagtgttg gttcatcacc ataaactgca
      721 gctgatgaac taaatactaa tcgttttaaa ttagattgat atttccgtgc taactcaagc
      781 aataaaagcg cactgtcaaa atttacacga tgtgtttcta caggccgttc tacagaatct
      841 gccacactag ctacagcagc tagatgaaaa atataggcaa actgatattc tttcatgatt
      901 ctttccatca attgagaatc tgatacatcc ccctcaatga aagtcacttg tttatccata
      961 tccaagtttt ctttttttcc cattgataaa tcgtcaacta ctacgatttt gttttctttt
     1021 cccaaataat tcgctagcgt tgaaccgata aaaccagctc cgccagtaat caatatagtg
     1081 tccatcaaat tcactccaat tgcacatttt cgtatcaaat aatattagtt taccattttt
     1141 atattgtaaa aactataaaa tttgttgaag ttgggataac tagttttctt ttctactttc
     1201 atatacctaa aaatagtttc aattagttac tccttcttct ttagatatag ttttttggat
     1261 agaacccaga tatccccaaa aaataaatga acctatcgta ctaaccaaaa tgagttctgt
     1321 gataaataat gccgaaactg ctattgtaag aatcattaaa atagcaaaaa agtgcttatc
     1381 ttttactaga tttggttgtg tgaaacaata acgcaaggct ttaaagcatt ggataaataa
     1441 gaaggttaac aatgtcaata gacctaatcc tcctgtagca gccatcacta agaaaataaa
     1501 attatgagca gttaaagtat cttttcccat taatgtatat ggtagtttat catgtgcata
     1561 ttcaatatag tagcctggag aacctccgga tatcggctta ctcttgaata tttcaattgc
     1621 acttttccaa agttcaaacc ttaaattaga aacatccccg ctatcagtgt cagggcgttt
     1681 taaatcaact ttattgctgc tagttgttcc tgatgaatca gatgtatctt tttttacttc
     1741 tgtaatatgc ggaacatgtg cccatgcatg agcagttata tctgttacat aatacatcgc
     1801 aattatactt agcaatccta ctactaatgc agttagccat ctttttaaag tattagtttt
     1861 aagaaaacga ctactataac ttgtaaagaa actaaaaaca aaagttgtta ttaataaaca
     1921 aactaatgtg gtgcgtgaac ccgataaagc aataaacgag aattgaataa aaatattaat
     1981 tacaaaaaat attttaaata gaagatttaa atgcttgtaa gtgaccaaat aatatatagc
     2041 aataatgatg acgattaatg atataaccgc accaaaattt ggatctgtat atacaccaaa
     2101 taaacggttg cctaaccacc ctaaacgaac tgggtaatac ttatatttta ttggaatttt
     2161 tatgccatat tgaatgacaa accagtataa tgatactaaa ttagctaaaa accataccaa
     2221 tgaaagtatc caggtaaata ctttgaaaaa aaagttacta ctatagtctt tgccaaactg
     2281 ataaatcata aagaaaaaga ttaattgcca catgattaac ttaatatttt cgctatatcc
     2341 atattttaaa ttcattaaac tgcttactag catcgcgcca ataaaagcaa ttaatagcca
     2401 atcatatttt tttagatttt tttctctaaa tgcaataatt gcatctataa tgatcaagac
     2461 aactcccgct attccagcag gccaaaaaag taaagtatca tatctagtag gtaatagtaa
     2521 atacgggcct attgctcgta acattaaaat aaaaccaaaa taaataaaat accaaccttt
     2581 cacatatttt aaaaatcttt cattcaacat ttttcctcca tccacctatt tctcataaat
     2641 atttcttatc ctttttagga taaactggtc ctttcaattc taacaaaaaa atgctaaact
     2701 aacaatgtat attaatgaat ttcgagaggt gaaagatgaa aagagtaatt acttacggta
     2761 cctttgattt gcttcattac gggcatatca atttactgaa acgagcaaaa caatacggag
     2821 actatcttat tgttgccctt tctacagatg aattcaattg gaatgcgaaa caaaaaaaat
     2881 gttattttag ttatgaaaaa agaaaacagt tacttgaagc tattcgctac gttgatttag
     2941 ttattcctga agaaaattgg gaacaaaaag taaaagatat aaaagaatac catgcagatt
     3001 atttcgtgat gggcgatgat tgggctggac attttgatga acttgaacaa ctaacagatg
     3061 cacaagtgat ttatttacca agaacacctg agatctctac aactcaaata aagaacgaac
     3121 ttaattcttt aaatagtgat aaataatatt ttttaaacaa taaaagaaca atatatctgg
     3181 ataagacgta aaaaaatggc tctataattt ctaggactga tagaattttc tgtcggtcct
     3241 agattttttg taaaaaaaaa cagacataaa aaaattccga tagaatagag tcgtctaaaa
     3301 catcaatctg aaaggaagtt tttgatatcc atttctcatt ctatcaaaga gctcttcact
     3361 attaaagata aaaatattga aattaattct tttcaagaaa ctttttataa ggacaagaaa
     3421 gccatcgtaa tcgaaggtcc attagttcgc acttttagac attgtctatt ttgtaaagaa
     3481 tctgcaaagc agatcgagaa aaacggcaag aagatttcaa tgattatctt aaatcgcagt
     3541 gggaataaac aaacctattt gcgtcttaga aaacaacatt accactgcca atcatgcggg
     3601 aaatatttta ctgctcatac gtatcttgtc gctccttcat gttttatttc gaaacaagtt
     3661 cattacacga tattagaaga gttgaccgag cgtcaagcat taaagacaat tgcgaaacgt
     3721 tgtgattttc agtaacgaca gttcaacgga cattatctgc tctatcggca acgctgcgac
     3781 agaagctaga ctatttacct cattgtttac tattcgacga gtttcgctct ctttcaattt
     3841 tccatgggaa gttctccttt tcttgtatga attgagagac agggaagctc tttgacattt
     3901 tgtccagccg gagaaaaaaa agatttgatt gcttatttca tgcgttttac aagaaaagct
     3961 catatggggg ttcgatacat tgtcacagat atgaatgccc cttatttttc attagtcaaa
     4021 gaacccttcc caaatgcaca aatcatcatt gattgctttc acattgggca acacttgaac
     4081 aagtttttcg atcgtgttcg aaaacgtgtg atgaagcagt tgaatcaaaa atgtcaacgg
     4141 cacctttaaa atgtaggaaa acggcaattt aaaattgttg gtttacctac atttttgtat
     4201 gctcttctta tcccaaatga aatggaggct cagggatgag aaaagacata cgcgaaggag
     4261 tgatgatcta cgtgatcaat gaaatcaaac ccaattatgc tgcactagca aaacaatacg
     4321 actgcgacta ccgaacagtt aagcatgctt acgaagaagc ccaagttaaa gaatcaaaac
     4381 ctccagaacg taagaagcgt ccaagtaagt tagatcccta cagagaaatc atccaagaca
     4441 aaatcaaaga ccaatgcagt gcttacagca ttttcaagtt tattgagcac aaaggatttg
     4501 gaggaagcta cagtttagta aagacctatt gtcgccagat taagcaggcg aaagtacaca
     4561 aggcaaccgt ccgagtcgaa catagccctg ggctttctgc tcaggttgac tggaaggaag
     4621 atatgcgact aatcagtaat cagggcgaaa tttttgagtt caatatcttt ttgtacgtct
     4681 tgccatattc caagaaaaaa tatgtcacac taactttcga ccgaaaacaa gacacactct
     4741 ttgagtgctt agatgatgcg ttttatcaaa ccggtggcgt tcccaaagaa atctggttcg
     4801 ataatatgaa gacagtcgtt gaccattctc gtagtcagtt ttccaaaccg catttcaaca
     4861 aacgttttta tgctttcagt aaggatgccg gcttcacacc aattgcctgt cggccatttc
     4921 gtccgcaaac aaagggctgt gtcgaagctt tagccagaac tgttgaccgc ctacgggtct
     4981 ataatcatga attttatgat gccgttgagc tgtgtcattt agtgaataa
//
LOCUS       DAIGQM010000105         5017 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.111, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000105 DAIGQM010000000
VERSION     DAIGQM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.111"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..863
                     /locus_tag="NOA48_002572"
     CDS             <1..863
                     /locus_tag="NOA48_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790798.1"
                     /translation="QGLQKKFGKFQALKDVSFTVNAGEVVGFIGPNGAGKSTTIRTLL
                     GIINRDEGDVQIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFIKLHGGGS
                     KAKRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVESDLYILDEPTSGLDPLMEA
                     VFQEEVEKIKNDGKAILLSSHILSEVERLADKVAIIRRGEVVETGTLDELRHLTRSTV
                     TLVTEGDIEKLATLSGVHDFVQKDGKATFSADNEAMNTILTEATKLGVTKIESVPPTL
                     EDLFMRHYEG"
     gene            887..2500
                     /locus_tag="NOA48_002573"
     CDS             887..2500
                     /locus_tag="NOA48_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0790799.1"
                     /translation="MNEKFARWNVLFIQYVKRDWKKIIVWVLGLGLFSGAFVPAFEEI
                     AKGQGLLGMFETMQNPAMISMVGPTPIKIGTDYTLGAMYAQEMLLFCGLFAMIISALH
                     VVSHTRKEEELGLTELVRSFRVGRQANSLAVISEMLLINLLLGLLIGGLMMSFGVKTI
                     DAEGAFLFGGSIALAGIIGGVLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSN
                     LDLSMFNPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPERE
                     GRATAKKSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQM
                     FTQSGVSIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLY
                     WTTIFLAIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGL
                     AALALGWLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGT
                     IFAVITVISIVFLFVGYLGYKRRDMVEGA"
     gene            complement(2572..3084)
                     /locus_tag="NOA48_002574"
                     /pseudo
     CDS             complement(2572..3084)
                     /locus_tag="NOA48_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            3347..3463
                     /locus_tag="NOA48_002575"
     CDS             3347..3463
                     /locus_tag="NOA48_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI0790800.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOA48_002576"
     CDS             complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOA48_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0790801.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(4588..4671)
                     /locus_tag="NOA48_002577"
     CDS             complement(4588..4671)
                     /locus_tag="NOA48_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI0790802.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
BASE COUNT         1546 a          869 c          992 g         1610 t
ORIGIN      
        1 tacaaggctt gcaaaaaaaa tttggtaaat tccaggcgtt gaaagatgtc tcattcacag
       61 taaacgccgg tgaagttgtt ggttttatcg gaccaaatgg agcaggaaag tcaacgacga
      121 tccgtacact gctaggaatc atcaacagag acgaaggaga tgtccaaata ttcggaaaag
      181 atgtttggaa agatagtcta gaaatccata aacgaatttc gtatgttcct ggagatgttg
      241 ctctttgggg cagcctgact ggtggagaga tcattgatct atttatcaaa cttcatggcg
      301 gcgggagcaa agcaaagcgc gattatttaa tcaaacgatt tgaacttgat ccaaagaaaa
      361 aagccaaagg ttactctaaa ggaaatcgtc aaaaagtcgg tttgattgct gcactttcag
      421 ttgaatctga tctgtatatt ttagatgaac cgacttcagg actagatcca ttgatggaag
      481 cagtattcca agaagaagta gaaaaaatca aaaatgatgg caaagcgatt ctattatctt
      541 cacatatttt aagtgaagtt gaacgattag cagataaagt agcaatcatt cgacgtggag
      601 aagtagttga aacaggtaca ttagatgaat tgcgtcattt gactcgctca acagttacat
      661 tggtgacaga aggcgatatt gagaaacttg cgacgctctc tggcgtgcat gattttgttc
      721 aaaaagacgg caaagcaact ttttctgctg acaatgaagc gatgaatacg attctgaccg
      781 aggcaaccaa attaggtgtg acaaaaatcg aatctgtacc gccaacgctt gaagatctat
      841 tcatgcgtca ttacgaaggc tgattgtcgg aacggaggaa aagaaaatga atgaaaaatt
      901 tgcccgttgg aacgtattgt tcattcaata cgtgaaacgc gattggaaaa aaataattgt
      961 ttgggtttta ggtttgggtt tgttctcagg agcatttgta ccagcatttg aagagattgc
     1021 taaaggacaa ggtcttttag ggatgtttga aacgatgcaa aatccagcga tgatctcgat
     1081 ggttggacct acaccaatca aaataggtac ggattatact ttaggagcga tgtatgctca
     1141 agagatgttg ctgttttgcg gattgttcgc aatgattatc tcagcacttc atgtggtgag
     1201 ccacacgcga aaagaagaag aattaggttt gactgaattg gttcgctcat ttcgagtagg
     1261 acgacaagcc aattcattag ctgttatcag tgagatgctg ttgatcaatc ttttattagg
     1321 tcttttaatc ggcggactca tgatgagttt tggtgtaaaa acgattgatg ccgaaggagc
     1381 tttcttgttc ggaggatcaa ttgcattggc gggaattatc ggtggtgtat tggcacttgt
     1441 gatgtcgcag attatggcga cttctactgg agcaaccggc tcgacattaa gtcttatagg
     1501 acttttgtat atcgtgcgcg ctggaacaga tgtgtctaat cttgatttat caatgttcaa
     1561 tccaatggga tggatttact tgacctatcc tttcacagaa aataactggc taccattatt
     1621 atttgctttg atttttagtc ttgtttttac cgtacttgcg tttgtgttgg aagaacatcg
     1681 cgacatgggc gcaggttatc ttcctgaacg agaaggacgt gcgacggcga agaaatcact
     1741 actttctgta cctggtttgt ttttcaagat taataaagga gtaatgattg gttggctgat
     1801 cgcatttgtc gttatgggag ctgcgtatgg ctccatttat ggagacatgc aagtctttct
     1861 tggcggaaat gaactgatga aacaaatgtt cactcaatct ggcgtttcca ttgaagaatc
     1921 ctttacggca acgatcatga tggtaatgat tggattagtc acaatcttgc caatcgcggt
     1981 ggtcaataaa ttatttgcag aagaaacaag actgcatctg agtcaactgt atgtaacgaa
     2041 gattacgcga ggccaattat attggacaac gatattttta gctatttttg ctggagtcgt
     2101 aggtattggc ttagcatcag cgggattagg tggaacggcg atttctgcga tgaaaaatga
     2161 atcgactatg gatctgaccg atttcttagc tgctggatac aattttctcc cttccatctt
     2221 attttatatt ggtttggctg ctttagcgtt aggctggttg ccaaaatttg gaaaagtaat
     2281 ctatgcttat ctaggctatt cctttgcttt gaattatttc ggcggaatct tagatttgcc
     2341 ggattggttc tcaaaaactg caattcaaag ttggattcca cgcttaccga tggaaaaatt
     2401 tgatggaacg atttttgcag taattactgt tatcagtatc gtcttcttat ttgtcggcta
     2461 tttaggatac aaacgccgtg atatggtaga aggcgcttaa aaattgaatt tctaaaaaac
     2521 cgttcatatt tacgaaagtc gatttgagcg gtttttttat ggcttcaatt gtcaaattaa
     2581 gtgcaacgat tcattaaaaa atacttcata aggggttttc caatttagac atttccgtgg
     2641 tcgcgtgttt aatttattcg cccattcttg aatttgacta tcgaaaatac ctgaaatatc
     2701 ttcacctttg ggtgaatatt ctcgtaataa accattagta ttttcgtttg taccacgttg
     2761 ccatggagca tgtggatctg gaaaatacac tttagtgcca tttaattcta gcgttattcg
     2821 actatgttgg gagaattctt ttcctctatc gggtgtaacg gttttacatt tatcttctcc
     2881 tacatttctt agtagattga tcatacaatc aaccacattt ttagagattt tcttttcaac
     2941 cttaccaagt agggagaaac gagatctacg atcgactaga gttacaatac gagccctacc
     3001 tgttttaccg gctacagtat cagcttccca attaccaatc tcaaggcgct cattggcagc
     3061 agatggcctt tcatggatct tattgtatgc agatgatcca atgacagcta gggcaccacc
     3121 aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa cccttcataa
     3181 aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac tctattcaag
     3241 cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa atcgtaaagt
     3301 atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg ttcaaaatca
     3361 acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa ttggaaagct tgcagccacc
     3421 tacaccacca atacccaaaa cacctaaact tccaggtatt taaaccttaa aaaaggaaaa
     3481 gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc tcatgttggg
     3541 gtcccgagcg cctacgagga atttgtatcg ataagaaata gatttaaaaa tttcgctgtt
     3601 tttttctaat ttcattttga ggtgaattaa ttggtagtta ttagaggtgc cctataccta
     3661 ataatttatc tacattccct ttagtaacgt gtaactttcc aaatttacaa aagcgactca
     3721 tagaattatt tcctcccgtt aaataataga taactattaa aaatagacaa tacttgctca
     3781 taagtaacgg tacttaaatt gtttactttg gcgtgtttca ttgcttgatg aaactgattt
     3841 ttagtaaaca gttgacgata ttctcgattg acccattttg aaacaaagta cgtatatagc
     3901 ttccaatatt tatctggaac atctgtggta tggcgggtaa gttttattaa gacactgttt
     3961 acttttggtt taggatgaaa gcattccgct ggcagcttaa gcaattgctg aatcgagact
     4021 tgagtgtgca agagcaaccc tagtgttcgg tgaatatcca aggtacgctt gtagaatcct
     4081 tcttcaacaa tcagatagat gtcagacgca tggctttcaa aaaccacttt tttaataatt
     4141 tgtgtgctta aatggtaagg aatactccca acaattttat acctctgttt gttagggaat
     4201 tgaaactgta gaatatcttg gtgaattaaa gtgacacgag tattcagttt taatttttct
     4261 gacgataagt tgaatagatg actgtctaat tcaatagacg ttacctgttt acttatttta
     4321 gccagtttcg tcgttaaatg ccctttacct gttccaattt cgtaaacggt atcggtttct
     4381 tttaaattca attgttttat tatttggttg agtacttttt cactcgttaa aaagttttga
     4441 gaatatttta tatttttgtt catgtaatca ctcctgaagt gattacatct ataaacaaat
     4501 acagaagtta aacgatttgt ttgtaatttt agttatctgt ttaaaaagtc ataagattag
     4561 tcactggtag gaattaatct aacgtattta tttatctgcg taatcactgt ttttagtctg
     4621 tttcaaaaca gtagatgttt tatctacata acgcatttgg aataccaaca tgacgaatcc
     4681 ctccttctta attacaaatt tttagcatct aatttaactt caattcctat tatacaaaat
     4741 ttttaatgca ctatcaacac actcttaagt ttgcttctaa gtcttatttc cataacttta
     4801 gggttaacca tacgcaagac caatcactct cggacaatac tcatgatttt aatgataaaa
     4861 tccatgttaa acccatagat aagaaataca cctgcaataa ccgttacctg tttgtgccaa
     4921 tttaaaaatg caccactttt ttataattaa aacggttgaa aactgtacca ctaataactc
     4981 acaatagaga gatgtcaccg tcaagttaaa tgtacaa
//
LOCUS       DAIGQM010000106         4953 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.112, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000106 DAIGQM010000000
VERSION     DAIGQM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.112"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(148..1110)
                     /locus_tag="NOA48_002578"
     CDS             complement(148..1110)
                     /locus_tag="NOA48_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0790803.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1112..2551)
                     /locus_tag="NOA48_002579"
     CDS             complement(1112..2551)
                     /locus_tag="NOA48_002579"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI0790804.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNKNWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2736..4682
                     /locus_tag="NOA48_002580"
     CDS             2736..4682
                     /locus_tag="NOA48_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HCI0790805.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1603 a          824 c          803 g         1723 t
ORIGIN      
        1 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacaagttga
       61 caactccttt ttgtttacaa atcaattgga tatctacaaa ttgtattttc taacgaattt
      121 tatagacatt aaaaaattaa tttaacgtta aatacttcct ccagaaagta ttgagattgg
      181 taaaatataa tccttatttg tcttttcgcc tttaattttt ttcagaagaa tatcaacaat
      241 aagacttgca atttcatcaa ttggttgtct tattgttgtc aattgtggga aaaatttctc
      301 aataaaagag gtaccatcgt atccaataat ttttaaatct tctgggatat taagtttaag
      361 ttgatgagca attttcatag tgagaatggc tgttaaatca tcagaaacaa aaataccatc
      421 tggtttgtga tttataatag ttgactttat ttccatttca cgacggatag tagacagatt
      481 attaggaatt ttgaaaattt ttccatttgg attttgaaaa gaaaaaccta gtgcacgtaa
      541 ttctgtggga gaatccgtgt tatcatttcc tgtaatcata atggtatttt gacaaccatt
      601 tttttgtaaa gtcttagctg caagttttcc cccttcaaag ttatctgaag aaacaatgga
      661 aacattagga gctaaatttc tatcaaaagc aacaataggt gctctcacac gctcataatc
      721 agcaattcca agattatggc ttgatgagat tatgccatca acttggttgg cttcaagcat
      781 ttcaatgtat tctctctctt tagcaggatc attttgacta ttgcaaataa tcgttttata
      841 tccatgttta aataactcta tttcgagata ctcaatgagt tcagagtaaa agatattact
      901 aatattagga aaaataagac caataagctg aggtgacttt ccttgaagtc cacgtgctaa
      961 attatttggt ttataaccaa gagttttcat agcttcatga actttttgtt ttgttttttc
     1021 tgataaatat cccttattat taatgacgcg tgaaacggtt gttgggctaa ctccagctaa
     1081 ttcagcgaca tcagttaatt ttgctaccat tttaatattt taattcaaag tattttccag
     1141 taggttcgcc tgatttgatt tgaataccat tttggtgatt ttcagggaat acacgactag
     1201 taaacacttt ttctccttta ttaataaaaa tctcaatgat tgagttatct acaaaaatgt
     1261 tagcagttgt ttctttagta tcaattgagc attcacgaat cgtaccaaag tcagtggcat
     1321 attgaatgcc tgctttgctg cgatctaaaa taatttttcc ttctttggta tctacaatca
     1381 agctaagtcc atttccttta ctatcagaga aaagaagtaa ctccgatttc tgatttggag
     1441 gaaaagttag ttcaagctca taagtattat ttgtttctgc ttttgctgta aattgttcag
     1501 aactagcacg taatgatgta atagcttcta ctggatattg gtaaagttta ccatctttta
     1561 ttgaaagttc ttttacaaga ctcattgctc cctgataatc atacttatca gttggataat
     1621 cgatatcagg tagtccaatc caactgacaa tcagagcacg accatcagga gtattgaatc
     1681 cttgagtcgc atacgcttca aatccataat caagattttg aatttctgaa gcgcccacaa
     1741 gttttacttt ttctatgtca agcgattgac agatcttaaa agtattcgga tagatattcc
     1801 cataatttag ctcagattta tccaaccctt gaggacaata aatgagaaca ggttttttgt
     1861 ctacaaatac tagatttgga cactcaatca tgtattctga accagtgccg ccaaaatcaa
     1921 ggttgccaac ttcctcccat gtttccacgt tattgtcatc cgctttgtaa agtttgataa
     1981 agcctgattt ttctaaattt tgtgctccaa caatcgcata caattgtcct tcataattaa
     2041 acatttgtgg atcacgaaaa tgatcagtta catcagcagg tttatgaata agaacattct
     2101 cacctttcgt aatgttgtag tctttatcca tccatgctcc gatttgaagt gtatcacgtt
     2161 cccaattttt atttcgaacg tttcctgtat agagtaagaa tagattcccc tctatttcat
     2221 atgcagaacc ggaataagcg ccgtggctat ctcgttttgt gtctggaaga agttctgctc
     2281 ctgttacatg aaaatgaact aaatcatctg attcattgtg tacccattct ttcaacccat
     2341 gagcagctcc aaatggccaa ttttgataaa aaagcgtata ttttccgtta aaaaaagaaa
     2401 aaccattagg atcgtttaac aatcctgttt taggttcgat atgatagcta gcacgccaag
     2461 gtgatcgttt tacattatcc ttaattttat ccatctcatc tttagtccaa tcagaataag
     2521 cacgatatcg tatttctcga ggtaagttca tattttactc cttcaattta tctttttaca
     2581 actagtatgg taaacgtttt ccgttgaaaa atcaatcatt tcatttaaaa aaataaacta
     2641 tatgacaaac gtttgacata tttttaagat atgctaaaat aaatttgcat ttcagtgaac
     2701 cgttttcacg taaaaataaa aaaggagtga ttcgaatgaa ttacagtaaa gtagcttccg
     2761 acgtaataca agcggtcgga aaagataacc ttattgcagc tgcacactgc gctacacgtc
     2821 ttcgtctcgt actaaaagat gacacgaaag tgaatcaaaa agctttagac gaaaatccag
     2881 atgtgaaagg cacatttaaa attgatggac aatatcaagt gattatcggt gcaggtgatg
     2941 ttaatttcgt ttatgacgaa cttatcaaaa aaactggact ttcggaaatt tcaacagatg
     3001 atttaaaaca aattgctagt aaagataaaa aattcaaccc cattatggca ttaattaaat
     3061 tattatcaga tatttttgtt ccaattatac ctgcccttgt tgcaggtggt ttattaatgg
     3121 cattacaaaa ctttttaaca gctgctggac tttttggacc aaaatcaatt gaagaaatgt
     3181 atcctgcgat tgaaggtatt tcctcaatga tccaactgat gtccgctgca ccattcatgt
     3241 tcttaccaat tttagtaggt atttcagctg ctaaacgttt tggagcaaac caatttcttg
     3301 gtgctgcaat tggtatgatc atgacaacac cagatcttgg tggctcaact gaatattgga
     3361 atatttttgg ttatcatgtt tcacaaacaa actatgctta tcaagttatt ccagttttag
     3421 cagctgtttg gatattatct atattagaaa aattctttca taaaaaattg ccatcatcta
     3481 ttgactttac attcacgcca ttattatcag taatgattac tggatttttg actttcacag
     3541 ttattggccc tgtaatgtta ttgttgtcta atggaattac agacattatt gtttggctat
     3601 ataacactac tggatttatt ggaatgggta tttttggagg aacatattca cttatagtca
     3661 tgactggttt acatcaatca tttccagcta ttgaaactca attactttca gcgtggacaa
     3721 atggtatcgg acatggagac tttatctttg tagttgcatc tatggcaaac gttgctcaag
     3781 gtgctgcaac atttgccatt tggttcttaa ctaaaaattc taagacaaaa agtcttgctt
     3841 cctctgcggg tgtctcagca cttcttggaa ttacagagcc tgccttgttc ggagttaact
     3901 taaaataccg ctttccattc ttttgtgctt taattggttc aggaattgct acagcagtag
     3961 caggattact taaagtagtt gctgtttcac ttggttcagc aggtttcttg ggatttcttt
     4021 caattaatgc aacatctatt ccattttacg tattgtgtga attgattagc tttgtagttg
     4081 cttttgcaat tacttacttc tacggtaaaa caaaagctgc tggtatcttt aaagcagaag
     4141 aaattgctga acaaacacca gttaattctt caaaagtagc aacaacagat ccaatatcta
     4201 ctgatgttga atcaacacaa acaaaagttt catcagaaac aattgttagt cccatttctg
     4261 gtaaagtgat tagtctttct tcagtaaatg atccagtctt ttcatcagaa gctatgggaa
     4321 aagggattgc cattaaacca aatggaaaca cggtccattc tccagtagat ggtactattc
     4381 aactcacgtt tgaaactgga catgcttatg gtattaaatc aaataatggt gctgaagttc
     4441 taattcatat tggtattgat actgtatcaa tgggaggaaa aggatttaca caaaaagtta
     4501 ctactaatca aaaagttaga aaaggcgata ttcttggagc atttgaccgt tcaatgattg
     4561 agaaagaagg tcttgatgat acaacaatga ttattgtgac caatacttcg gattattcag
     4621 aagtaaatat agtagctgaa aatacagtca ctgagggtac tgatttactt gaaatcaaat
     4681 aaatatattt ccctgagtaa agatggaatt ttctttccaa aatcaaataa tatagattaa
     4741 tcaaatattt gagaataaca ttttatttaa tcttttcata tatcaattgt atgaaaaatt
     4801 attagaattt taaaaaatga taaaaattca aaaagaaaaa atagtagtta tttacttgtc
     4861 atgttactaa ataaaaaaat aatttaaata tgatatatag tcatttattt agtgatttca
     4921 ttctaaaata aagggagaaa tgtctatgct ata
//
LOCUS       DAIGQM010000107         4930 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.113, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000107 DAIGQM010000000
VERSION     DAIGQM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.113"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            84..971
                     /locus_tag="NOA48_002581"
     CDS             84..971
                     /locus_tag="NOA48_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0790806.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1111..2037
                     /gene="cysK"
                     /locus_tag="NOA48_002582"
     CDS             1111..2037
                     /gene="cysK"
                     /locus_tag="NOA48_002582"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCI0790807.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2273..2719
                     /locus_tag="NOA48_002583"
     CDS             2273..2719
                     /locus_tag="NOA48_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0790808.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2992..4344
                     /locus_tag="NOA48_002584"
     CDS             2992..4344
                     /locus_tag="NOA48_002584"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCI0790809.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4515..4802
                     /locus_tag="NOA48_002585"
     CDS             4515..4802
                     /locus_tag="NOA48_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790810.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1694 a          813 c         1030 g         1393 t
ORIGIN      
        1 attaaaagta taatttaatt aattaagttt gttttaagaa gagaactttt tattaagttt
       61 ttttattttg aggaggaatt tgaatgcaag agctgaagac ccgcagtgcc cggcaccata
      121 gacctaaaag aaaaatggtg atcaataaaa aagcgattgc tcctttaatt ggaacgagtc
      181 ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca gatgaacaag
      241 gatctcaaac agtcgctgat cctcaagcgt ttatcgatca aatcggctgg tctgcgtcag
      301 aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg ttgttggaaa
      361 gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc ggtgtgaaag
      421 gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaaac ggacaatggg
      481 taacgatgaa tgagccattc cgaaaatatt cttcttattg ggaatccttc caagaccatg
      541 cgaatgttct tcgttcaacc agtttttcca cgggcgatta tcattatgct ggcgtgtgga
      601 aaagcaatac aacaagtttt tatgatgcaa cagcgtactt gacaggtcgt tatgctaccg
      661 atccaaatta tggggccaaa ttgaactcat tgattaatac ttataattta acccgttttg
      721 atacgccatc aacaggttcg gctacaacaa ccacaagtac aacaacaacg actactacga
      781 cgacttcaac gtcatcatct tcaacaacag atgtaaatac aaataatggt cagacatata
      841 cagtcgtgtc aggtgatacg ctatgggata ttgcacaaaa atttggcatg tctgttgatg
      901 atctaatggc gaaaaatggc atgtctatgt ccagttattc tttattagtt ggtcaagaac
      961 taaacgtttg atttagataa aaaggcaaag aaattaccat atatggtata tctttgtctt
     1021 ttttttgcta gtcaaagacg aatcactcgc cataaatgaa cagattgtat tatgataagt
     1081 aagaagagca aagacaagga ggaattgaag atgacagcta tctataactc agtcaccgaa
     1141 ttgattggca aaacgccaat cgtcaaatta aataaaatcg taccagaaga ttcagcagat
     1201 gtttttgtaa agcttgagtt ttttaatcca ggaggaagtg taaaagatcg tattgcttta
     1261 agtatgatag aaaaagcaga acacgatggt ctactgaaac caggtgatac tatcattgaa
     1321 cctacttctg gaaatacagg aatcggattg tcgatggtag gagttgcaaa aggatataaa
     1381 gtaatcatcg tgatgcctga gacgatgagt atcgaaagac gtttattgat gaaagggtac
     1441 ggcgcagagt tgattttgac tcctggtgcg gatggtattt ctggatcaat cagagaagca
     1501 gaacgtttgg caaaagaaaa cggctacttt ttaccattac aatttgaaaa tgaagcaaat
     1561 cctcttgtgc atgagaagac gactggtcct gagatacatc aagcatttgg agtaaatggc
     1621 ttggacgcgt ttgttgcagg tatcggtaca ggaggaacga tcactggcgc tggccgagaa
     1681 ttaaaacgtg tgtatccgaa aatcgaatta atcggggtag aaccagcaga atctgctatt
     1741 ttagaaggga aagaagcggg acctcacaaa atccaaggaa tcggtacagg ttttgttcct
     1801 aaaacactgg atacttctgt gtatgataaa gtcctttcta ttagtggaga cgaagcgatg
     1861 gaaacagcta gagaagttgg gcgaaaagaa gggattttag taggcatctc atctggcgct
     1921 gcaattgctg ccgcgctaaa agtcgcaaaa gaattaggaa aaggcaagaa ggtattagct
     1981 gtggttcccg acaatggtga acgttattta tctacagccc tttaccaaga gatataaggc
     2041 acttggtttt tctccagata ggtttatgta aaaaactttt aaagatgaaa agaacacaca
     2101 aaaatttatg atgagaaaaa ttatttgaat agagacgtag aatagtgaac gcgactgttt
     2161 tacgtctttt ttcattaaaa tacaataaaa ttgaattttc ttttcatgtt aagtggattt
     2221 taaaatgtaa aaatagtatg ataagacgag aataacaacg tggggtgttt acatggaaaa
     2281 taagttagtc gaagaggtta tcgaaaagtt aaaaaaagag aacattcgaa tcacacctca
     2341 acggtacgcg gttttagaat atttgattga acatcattcc catccaacgg ctgatgagat
     2401 ttataaagca cttgaacatc ggtttccaaa tatgagtgtt gcgactgttt acaataacct
     2461 tcgcttattt acttcgattg gatttgttca agaaatgaag tacggcgatg cttctagccg
     2521 atttgatttc agttcaaagc gtcattatca tgtaatttgt gaaaactgcg gtaagattgt
     2581 tgattttcat tacccagggc ttgaagatat agaaatggct gcaagcagac tgactgattt
     2641 tgagattaat gaacatcggt tggaattgta tggactctgt ccggattgta aagagtcagc
     2701 aaaaaaggcg caaatgtaaa aacagtttct acaagtgtta tacctaaaaa aagctagctg
     2761 tgtaaaaaaa acgctagctt ttttattttt ttgtctttta ttcacaatct tagatataaa
     2821 agtgaatatt attaaaataa gaatcttgta gatattgggt tcttatgctt gaaaaggaat
     2881 gaaactacaa acaaaccttt gtgaattcac aagcattaaa ctgttgtatc cgttttattt
     2941 ctgttatagt agttttgtcg aaggacaaaa tgttaatcgg agggaccata aatgaaagta
     3001 gtagtaattg gctgtactca tgcaggtact gcagctgtaa aaagtatttt aaaaaatcat
     3061 ccagaagcag aagtgacagt atatgaaaga aatgacaata tttctttctt atcttgcggt
     3121 atcgcacttt atgtcggcgg agtagtaaag gacccagcag gcttgttcta ctcaaatcct
     3181 gaagaattat cttcattagg agcaacagtt aaaatggaac acgatgtaac agacgtcgat
     3241 acagaaaata aaacagtaac ggcaaaagat ctgaaaacag gagaaacaga aacggtttct
     3301 tatgataaat tagtgatgac aactggttca tggcctatta tcccaccgat tagtggaatc
     3361 gatgcgaaaa atgtactcct atgcaaaaac tacaatcaag caaatgaaat tattgcacaa
     3421 gcgaaagaag caaaacgtgt agtaattgtt ggtggtggat atatcggtat tgaattagta
     3481 gaagcttttg tcgaatctgg aaaacaagtg acattgattg atggattaga tcgcatcttg
     3541 aataaatatc tagataaacc attcacagat atcttagaaa aagaattgac agaccgcggt
     3601 gttactcttg cgctaggcga aaatgttact gaatttatca cagatgaaga aggaaaagtg
     3661 aaacaagtag ctacaccaac agatacattt gatacagata tggtcatttt atgtgtgggc
     3721 ttccgtccaa atacaaaact gatcgaagga aaagtagata cactgccaaa cggggcaatc
     3781 aaagtgaatg aatacatgca gacaagtaat ccagacattt ttgcagctgg agactctgca
     3841 gtagtcaact acaatccaag tggcacgcaa aactatattc ctttggcaac aaatgccgtt
     3901 cgtcaaggtt tgcttgtggg aaataacttg acagatcata aaatggcgta tcgtggtact
     3961 caaggaactt caggacttta cctatttggc tggacgatcg gttcgacagg tgtgaccaaa
     4021 gaaagcgcaa ctttgaacga tctagaagtc caagcgactg tatttgaaga taattatcgt
     4081 ccagagttca tgccaactac tgaaaaagta atgatggagc tagtctatga aaaaggaacg
     4141 aatcgtatcg taggtgctca gttcatgtcc aaatacgaca ttacacaatc agcaaatacc
     4201 atgtctttag ctgttcaaaa taaaatgact gtagaagatc tcgcactttc agatttcttc
     4261 ttccaaccac attttgaccg cccatggaat tacttgaacc tacttgcaca agcagcgcta
     4321 ggcgaaatcg aaactgcaca ataaagaaaa agggttgtga cacaattttg tcacgaccct
     4381 ctgtcttttt ttgtgaaaag tacaattagt tgtctttctt cgaatttttt gtcacaataa
     4441 gcagcaaaga taaagctgtt acataaaaga acaagcagct ttatttgatt ttgaaaagaa
     4501 aggtgagaaa gaagatgaat aaagaatatt ttgtccaaca agatgcattt ttagaagatt
     4561 ataaaagtgc ttcgaagaaa ttaacgatca atattgatga gttggcagat caagtactct
     4621 ctcagttgaa tgaaacgcaa gaggaatatt acacgatgcc agcaaatgac gccaaagata
     4681 atgtttctca tcgttttcct ttcagtagac gcatctactc agatgaaaat gacggcacat
     4741 tgaatacaga gtacacatat gaaggtcagc catatgtgct agaaactgat gatgatcttt
     4801 aaagacagtt tttgaaaagg ccgctcatcc ttaagtgatg acaaaaaatc atcacaatta
     4861 ccgatgactg tctctttact atcttttaat cagaaaaagg ggttatgaca agctttgtca
     4921 accccttttt
//
LOCUS       DAIGQM010000108         4922 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.114, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000108 DAIGQM010000000
VERSION     DAIGQM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.114"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..498)
                     /locus_tag="NOA48_002586"
     CDS             complement(<1..498)
                     /locus_tag="NOA48_002586"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790811.1"
                     /translation="MVEILKEITTYEIIEKTTGLTCYTYQQANEKYRLHFFCYVFDNQ
                     DELLANYEEINDQIAYSFQSQLKRKIERWNIYFFLFVKAKVAKPIKASIEQDKYATRK
                     VIVDNFREFATNDAQKEAQKEAQKEAQKNKIQKRLLLNLEQTKPVKKLAKDERQNDEK
                     IIHLLA"
     gene            complement(514..1353)
                     /locus_tag="NOA48_002587"
     CDS             complement(514..1353)
                     /locus_tag="NOA48_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790812.1"
                     /translation="MYVEREGKCYLTGIITKLQSAGQQGIVEGIHIAHIVAFFLEEFD
                     IMLVPRCLNDFSEYLASIINELREVGGQENKLIFLIEKCYRECFSDITPKLIHNRLSD
                     YLFLPSQKNEDYTNKFLWIAWLEILLYKLLQTNIAFEIDDCFKLLTQEKERAGIHVLF
                     TNHLTLDRFIGSLFRSTLYDKLDKQDVLFVTNQRRKFRGGSIAKREQIEGIVVNIDHP
                     EVSDRLTIDNPNEKKLFPIVHVDYIENEIDQILHDTKGLTAVEFSQRFPEELTRLFEE
                     IAN"
     gene            complement(1806..2900)
                     /locus_tag="NOA48_002588"
     CDS             complement(1806..2900)
                     /locus_tag="NOA48_002588"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790813.1"
                     /translation="MQGQDCNEREMITVKALPAYDGDCLIVQYGEEDQRTNLFVDGGQ
                     GQQVVRQLKEEIATISQKGECIDLLVLTHIDADHIRGFLSLFSQSSFDKSCIKRVFFN
                     SRKLLSQKFDTKVVYDDQLEIVQEKSEISFKQGESFDRYLENLRIEKMTVIDNSCQPK
                     LLNGAKMTILTPDEASLRKLYTDWEKAIQKETRDQLISGRNVNHQGSVEELIKKAFQE
                     DRAVANGSSISFILEYEGKRLLMLADAHPSTVTAKLKELYGEKELHFDLVKVAHHGSK
                     ANTSDDLLKQIECENYLISSNKGNRHGFPHKEALSRIVYHNYTKKRPTNFYFNYSDAS
                     EGLFTNEEIKKYGIQLIKKKMNERVLTIDI"
     gene            complement(3319..3729)
                     /gene="arsC"
                     /locus_tag="NOA48_002589"
     CDS             complement(3319..3729)
                     /gene="arsC"
                     /locus_tag="NOA48_002589"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HCI0790814.1"
                     /translation="MKKIYFLCTGNSCRSQMAEGYARQLLSASDVEIKSAGIETHGLN
                     PRAVQVMAEDGIDISNQTSDLIDQDYFTQADLIITLCGDAKDKCPTIPVGVQHIHWDL
                     TDPAQAVGTEAEITSAFRKTRDRIKAMVIELKNQ"
     gene            4283..4846
                     /locus_tag="NOA48_002590"
     CDS             4283..4846
                     /locus_tag="NOA48_002590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790815.1"
                     /translation="MFGFIALMFFLPLTKTHADVTVTNDCTDPSHSFTASINADNGKD
                     VSSDYYKVTVGQTESWRRNDPRGHILAIVYLEQLRTYYTPTNAAYSFKDGKLYSQGST
                     TEITPLKVETNSLVTRSMNVNMINLSTSLTTVSLSKWKSGGSTDYFALNHLDSETWSR
                     NDDPRGFLVSVLYNGGFSKEYIYYLPI"
BASE COUNT         1491 a         1025 c          719 g         1687 t
ORIGIN      
        1 tgctaacaaa tggatgattt tctcatcatt ttgccgctca tccttagcca gtttctttac
       61 tggttttgtc tgttccagat tcaataataa tcttttttga attttatttt tttgtgcttc
      121 tttttgtgct tctttttgtg cttctttttg cgcatcatta gtagcaaatt ctcgaaaatt
      181 atccacgatc acctttctgg ttgcatactt gtcttgttca atactggctt tgattggctt
      241 cgctactttg gctttgacaa aaagaaaaaa ataaatattc catcgttcaa tcttcctttt
      301 taattgactt tgaaaactgt aggcaatctg atcgttgatt tcttcatagt tggctaataa
      361 ctcatcttga ttatcaaata cataacaaaa aaaatggagt cgatactttt cgtttgcttg
      421 ttggtacgtg taacaggtca atcccgtcgt tttttctatt atttcatacg tagtgatttc
      481 ttttaatatc tctaccattg ttacctacct ccattagttt gcaatttctt caaacaaacg
      541 agttaactcc tctggaaacc tctgagaaaa ctcaacggct gttaaccctt ttgtgtcgtg
      601 taaaatctga tcaatttcat tttcgatata atcgacatga acaataggaa ataatttttt
      661 ttcattggga ttatcaatcg ttaaccgatc agaaacttct ggatgatcga tgttcacgac
      721 gattccctca atttgttctc gcttggcaat actcccaccc cgaaattttc tcctttgatt
      781 agttacaaac aaaacatctt gtttatcgag cttgtcataa agtgtacttc taaataaact
      841 cccaatgaaa cggtcaagtg ttagatgatt tgtaaataat acatggatac cagctctttc
      901 cttttcctga gtgagtaatt tgaaacaatc atcgatctca aaagcaatat ttgtttgtaa
      961 taacttgtaa agcaagatct ccagccaagc gatccacaag aatttattgg tataatcctc
     1021 atttttctga gaaggaagaa acaggtaatc acttaaccga ttatggatca atttaggcgt
     1081 tatgtcggaa aaacattcac gataacattt ttcaatcaga aaaatcagct tattttcttg
     1141 tccacctact tctcgtaatt catttatgat agatgccaaa tattcactaa aatcattcaa
     1201 gcaacgaggt accagcatga tatcaaactc ttctaaaaag aaagcaacga tatgtgcgat
     1261 atgaatccct tcaacaattc cttgttgccc cgctgactga agtttcgtaa taatcccagt
     1321 caaataacac ttcccttctc tttcgacgta cactcctgat cctgagcaac ctcgtatgtt
     1381 ctcatactcc gtgttgttag acgatcctat ttcattgtcc agtaccaatt taaaaatatc
     1441 tggcttactg atttgagttg cctttcctcg ataaggagtt ccaccgtctt ctttcataca
     1501 ctctggataa ccataaaata cgatttcttg cttattttct ggttccatta taagcagttc
     1561 aggataacct ttttttacct tcactttgat aatcgctaaa tctagactat ctgagcatct
     1621 tggcggttct aagatttcta gttcagattg ggtataatca aacagtttga agtcattaat
     1681 tgtttcccca accacacaat gttttgcggt gatcacaaaa cccgtttcac aatcctgctg
     1741 atacaacaaa cctgaaccat aagtattggt tcctctaata ttcactgata actcttcaaa
     1801 atcattcata tgtcaatcgt tagtaccctc tcattcattt ttttcttgat caattgaatc
     1861 ccgtattttt ttatttcttc atttgtaaat aacccctcac tcgcatcgga ataattaaaa
     1921 taaaaattcg ttggtcgttt ttttgtgtag ttgtggtaaa caatccttga taaggcttct
     1981 ttgtgcggaa aaccatgacg attcccctta tttgaactaa tcaaataatt ttcacactca
     2041 atctgtttta ataaatcgtc actagtattc gctttactcc catgatgagc cacttttacc
     2101 aagtcaaaat gcagctcttt ttccccatat agttctttta acttcgcagt gacagtactt
     2161 ggatgagcat ctgctaacat caacagtcgt ttgccttcat actccaatat aaagctaata
     2221 ctgctcccat ttgcgacagc gcgatcttct tggaaagctt ttttgatcag ttcctctacg
     2281 cttccctgat gattgacatt tcgaccgctg atcagttgat ccctggtttc tttttgaatt
     2341 gccttttccc aatctgtata taatttcctt agacttgctt catcaggtgt caaaatcgtc
     2401 atttttgccc cattgagtaa tttgggctga caagaattgt caataactgt catcttttca
     2461 atcctcaaat tctccaaata ccgatcgaaa gactcccctt gtttaaaact aatctctgac
     2521 ttttcttgaa cgatctccag ttgatcatca taaacaacct ttgtatcaaa cttttgcgat
     2581 aacagctttc tagaattaaa aaacactcgt ttaatacatg acttatcaaa actcgactga
     2641 gaaaacaaac tcaaaaatcc ccgaatatga tcggcatcaa tatgtgtcaa aaccagtaag
     2701 tcaatgcact cgcctttctg gctaattgtt gcaatttcct ctttcaactg cctaacaact
     2761 tgttgtcctt gacctccatc gacaaacaga ttcgtccgtt gatcttcttc tccatactga
     2821 acaatcaaac aatcgccatc ataagcaggt aaagctttca ctgtaatcat ttctctttca
     2881 ttgcagtcct gtccctgcaa tctcctcctt cttctgcttt cttttcgctg atcttgttat
     2941 tctttactaa ccaaaatcac acacaataaa cttctattca tttgttattg gcactggaat
     3001 tcagctgaca agaagagctt tcagtccatt agttaattgc gcgaaataca ctcttttctt
     3061 tcttatctta ctccccataa cattgttatt gtaaataaat tttgattttt aaacgccaag
     3121 cattctcata accagaaata attgcttgat tcataactcg ccaaataatt gagaaggcga
     3181 ccaaaaaata gcacaagcaa aaaaagccag caagaccatt ttaaggcttg ctgacttcaa
     3241 ttcttgattg ttaaaattta gcactataca gacaaatgaa gctcaaatga tcactcaatt
     3301 cccaaaaaat actgactctc actggttctt gagttcaatt accattgctt taattctatc
     3361 tcttgttttt ctaaaagctg atgttatttc tgcttcggtt ccaactgctt gtgcggggtc
     3421 tgttaaatcc caatgaatgt gctgaacacc tacaggaatc gtcggacatt tatcttttgc
     3481 atctccacaa agcgtaataa tcaagtctgc ttgtgtaaaa taatcctgat cgatcaaatc
     3541 agacgtttgg tttgaaatat caattccatc ctcagccata acctgaaccg ctcgtggatt
     3601 cagtccatga gtttcaatac ctgcgctttt aatttccaca tccgaggcag ataataattg
     3661 acgtgcatat ccttccgcca tttggctacg acaagaattt cccgtacata aaaaataaat
     3721 ttttttcatt tttatttctc ctcctggata tgagcattca atatagctcg gtcattattt
     3781 tattctctaa ctaaaagcaa gcatacagga atttttgtag gaaagcatca aaaaagagtg
     3841 aaatgattga aaagttacgt catcaattat cagtttggta tgttttggcc atcagttctg
     3901 atcttctttt tacctgataa ataataaatg gcattatcca tggatcgcct aaaattgaag
     3961 aaaattcatc atattcgatg tcatgaatca tttcctaaaa gaattttttt actaacgaat
     4021 gctaaatgaa cgctttgttt taaacggtag tttgaagaac cttattctat tgaaagaagc
     4081 tagaataacc gtagctatta gcaccccacc cataatttca ctacatttgg ttttatacta
     4141 aaaaaatgaa ataaattgat tgattgaaca cattgaaacc taaacttgtt cctttaaact
     4201 taaattgtaa gcgaagatcg tttacataaa ttatattaaa gggaggaata ccataaaaaa
     4261 aaaattacca ttggtcagcc tattgtttgg tttcattgct ttaatgtttt tcttaccact
     4321 aaccaaaaca catgctgatg tcaccgtaac aaacgattgt acagatccgt cacattcatt
     4381 tacagcttcc attaacgcag ataatggaaa agatgtctcg tcagactact acaaagtaac
     4441 agttggacaa acagaatctt ggcgtagaaa tgatcctaga ggccatattt tagccattgt
     4501 ttatttagaa caacttagga cctactatac tccaactaac gctgcctact cttttaaaga
     4561 tggaaaactt tattcccaag gtagcacaac agaaatcact ccgttaaaag ttgaaacaaa
     4621 ttcgcttgtt acgcgaagca tgaacgttaa catgattaat ctttctacaa gtcttacgac
     4681 agtatcgtta agtaaatgga aaagtggcgg atcgacagac tactttgcgc taaaccacct
     4741 tgatagtgaa acttggagca gaaatgatga tccaagaggc tttttagttt cagtcctata
     4801 taatggcgga ttctcaaaag aatacatata ttatttacct atataaattg agttaaattg
     4861 tattcgtttt tcctcctata ggcgtatact aaagaaaaca cttgaggagt ggggaacatg
     4921 ga
//
LOCUS       DAIGQM010000109         4801 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.115, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000109 DAIGQM010000000
VERSION     DAIGQM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.115"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            5..862
                     /locus_tag="NOA48_002591"
     CDS             5..862
                     /locus_tag="NOA48_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0790816.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQRRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            884..1393
                     /locus_tag="NOA48_002592"
     CDS             884..1393
                     /locus_tag="NOA48_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0790817.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1430..1831
                     /locus_tag="NOA48_002593"
     CDS             1430..1831
                     /locus_tag="NOA48_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790818.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1943..2296
                     /locus_tag="NOA48_002594"
     CDS             1943..2296
                     /locus_tag="NOA48_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790819.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2330..2773
                     /locus_tag="NOA48_002595"
     CDS             2330..2773
                     /locus_tag="NOA48_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0790820.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2790..3875
                     /gene="uxuA"
                     /locus_tag="NOA48_002596"
     CDS             2790..3875
                     /gene="uxuA"
                     /locus_tag="NOA48_002596"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0790821.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3868..4581
                     /locus_tag="NOA48_002597"
     CDS             3868..4581
                     /locus_tag="NOA48_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0790822.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         1659 a          734 c         1083 g         1325 t
ORIGIN      
        1 ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca cgaaaaaaga
       61 tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact cttttgaacg
      121 ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac tttataaaga
      181 tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca ctcaattaag
      241 ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcgaa gagcagaaga
      301 agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca cgaaagcggg
      361 attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg tccaatatat
      421 ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg cactttttcc
      481 ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa gacaagcttt
      541 cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga cagcgattga
      601 aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact atgtaaaagt
      661 agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg aaattcttga
      721 tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact tgttctatac
      781 gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat taattgtgct
      841 agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg tagtcaattt
      901 agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat ctcaaaaaag
      961 tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat ttatgagaga
     1021 tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta caccagagaa
     1081 agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt tgatcgcaaa
     1141 aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag aattgaatat
     1201 tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat ctgtttattt
     1261 aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg taaagaatat
     1321 ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat tgaacaagtt
     1381 tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa tgaagaagaa
     1441 cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc gccgtacaaa
     1501 aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta tgagaacaga
     1561 tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt atgttggaga
     1621 tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc atgcattagg
     1681 aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact ctatattatt
     1741 gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata acaaaaatcc
     1801 tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag catttgggag
     1861 ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa cttttattcg
     1921 aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg atccgagtgt
     1981 agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca gcgtgagatc
     2041 gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag atacaccgct
     2101 acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag ttgataagtt
     2161 gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc agttcttcta
     2221 tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca atcagattat
     2281 tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa tgttggaaat
     2341 catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg aagtaattgt
     2401 cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca tccaaacatt
     2461 cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca tgctagtatt
     2521 tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca atgaactgac
     2581 tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa tgttgttaga
     2641 agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac aaattgtcaa
     2701 acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa aattagatga
     2761 ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg tatggtgaaa
     2821 aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat gggataattg
     2881 gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt gaggagttga
     2941 aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta gcgatccacg
     3001 atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat atacgaacaa
     3061 tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa ccaatttttg
     3121 gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct cttttatacg
     3181 atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata cacagccagt
     3241 caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc gctcagctgg
     3301 aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact tattttttag
     3361 aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat ccagatgatc
     3421 cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac ttgaagaaaa
     3481 ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga tctttagggg
     3541 caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc atccattttg
     3601 tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg gcacatccct
     3661 ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa gaagggttcg
     3721 acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct atgcctggat
     3781 atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat gaggcgataa
     3841 gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat ctttgatatg
     3901 gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa atcagcacaa
     3961 aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca aacagaaatg
     4021 gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat caaatggcga
     4081 gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt atatacgaaa
     4141 aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac aatcgtggct
     4201 tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct atatgccttg
     4261 tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc agagatcttt
     4321 ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt tgaagactcg
     4381 attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat caaagatcat
     4441 ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt aagtttatat
     4501 gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg atttttagaa
     4561 agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta tttattgtcc
     4621 tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt atctacctta
     4681 tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta ccagtagatg
     4741 cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta tgcagatttt
     4801 t
//
LOCUS       DAIGQM010000110         4788 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.116, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000110 DAIGQM010000000
VERSION     DAIGQM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.116"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            564..989
                     /locus_tag="NOA48_002598"
     CDS             564..989
                     /locus_tag="NOA48_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790823.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            1019..1183
                     /locus_tag="NOA48_002599"
     CDS             1019..1183
                     /locus_tag="NOA48_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790824.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            2141..3118
                     /locus_tag="NOA48_002600"
     CDS             2141..3118
                     /locus_tag="NOA48_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0790825.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     YFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQIYSEKDPTSLQEKIKEQKRKLELL
                     QQLEELERKQNNLNKENKEINEQIPDNNSDIPPELKKGLLDNLQNLFKE"
     gene            3128..3625
                     /locus_tag="NOA48_002601"
     CDS             3128..3625
                     /locus_tag="NOA48_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790826.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            4001..4282
                     /locus_tag="NOA48_002602"
     CDS             4001..4282
                     /locus_tag="NOA48_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790827.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            4284..4700
                     /locus_tag="NOA48_002603"
     CDS             4284..4700
                     /locus_tag="NOA48_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790828.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1757 a          817 c          786 g         1428 t
ORIGIN      
        1 aaaaaaaaaa gaaaaatccg cttctgcgaa ttcttctttt ttcattttgg ggcgctgccc
       61 taatccctaa gtcccggtta ttcaatagca tggaaactca aagaataaga cgttccctgg
      121 aataaaaaaa aggctgctcg ttcgagcagt ccatacatag gaaaatgaaa aaacgacgtc
      181 ccttactgag aaacgctatt aaacttttaa caaatcctct aaaaaataac aagtctttaa
      241 aaagtgaccg gtaaaaatgc acaaagaact aaaaaagaga aattgcatca aatcaagcat
      301 tagaagctag taactagcta gaccaattga aaatcacaaa gtgagcgcct gtatctattg
      361 ctacaggcgc tacttggcat agtcgacatt atgtcaacaa gaatttaata taacatattt
      421 ttctagtttg ttataacaat gccactctaa caaaaatgta agcattatcc ttattaaaag
      481 ctccttgaca aggactatac cttttatttt atgattttta catagaaaac gttttctcta
      541 ttttttgttt agaggtgatt tttatgattt gcaagaacaa gaaaaaaatt attgctatta
      601 ttgctagttt ctctttgatt tttagtactg catgtactgt cttattaaca aataatgcta
      661 atgttgaagc tgcaagctct tcttacaaac ataatcatgc tggttataga tgttacaaaa
      721 tgagttatta tgtaagtcct tctaaatgca aacaattggc tcgccaaact aataaactta
      781 ataccgtctc agctattgca aactttattg gactatctgg attaacaccg gggattatat
      841 cattagtttt cggatcagca gttagtgcta ataatgtatt tgttacagcc gctagaagag
      901 gaaaaggcgt tcaattaaat tatattgccc attttagtaa taccactacc tataattata
      961 gttctaacca aaattatgtt ataaaataat taaaacttta aactaggagg aatgctttat
     1021 gaaattaaca aaaattgctg taattttagc tgttattgct ggcattattt tatattttgt
     1081 attgcctgct aatcaattct tcctttactt tggaatacct gcgattttaa tagtaaatgg
     1141 cgtaagaatc tttgaacaac gaaaaaaatg tagctctacc taatcgttac aaaacaacaa
     1201 tttcaccttc ggtgaaataa gcgaaacttt acaaaaagtg gctagcaaat gctagccttt
     1261 tttgtattgt agagcgtgaa ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1321 aagcggttat ttgcaccaaa tacctccgta tttggctagc aatccttcta aaaaatacac
     1381 ctatcgatca gagtcaaaac aaatcaattt tcgagtgagc gaatccgaat ttgcaaagct
     1441 gaagctttgc aaatgagtgt gccggcttcc gtaaaaatac atatggctat aatttgcgtt
     1501 ttaaggcgtt ttaaacgttc tggtatataa ttataccaaa acaactttaa aacgccttag
     1561 atctaatttt agaggtctta tagaacattt tagggttgtt agggcttgcc ctgaccgcct
     1621 gtaaggcgct ttgagaacaa gataagggtt ttatactaag actgtcttaa aacggcttaa
     1681 acaaacgctc agaacttttc aaaggagttc tttatgaact gtttttaagc aaaggagcct
     1741 ttaggcgact gcgcagtata atgtgagagc gtagcgatca cacattttta gtgaccgtag
     1801 ggagcgagtt tcccagttta gaaaaattcg cgaacttgtt tgaggaaaaa agcaggagtt
     1861 ttttaggcgg gaaattttgc ctcctctttt ataatctctt tttaaacctc tttttaaacc
     1921 tctttaccgt cggctgtatg cttactctcc caaggtgtgc agaatctttt gggggtcttt
     1981 ttgtctgttt ttaggggtct ttttgtctgt ttttaggggt ctttttgtct gtttttgggg
     2041 gtctttttgt ctgtttttag gggtctttaa ttaggggctt gacccctatt agaaagctct
     2101 ttataatttt gttaagtagt taatcttgaa ggaggatttt atggcaaatg aaattgtgaa
     2161 ataccaccat gaattaaata cgattccttt acgcaaattt acgtcagtag aaatgaattt
     2221 attcttctct atagtatcta gaatgcgtga cgtaggcgat aaaaaagtac aatttacatt
     2281 cgaacaatta aaagatttaa gcaattataa agcaactgca aatgttcgat tcatagatga
     2341 tttagaaaca acgtatgaca aattaatgga tttacgtttt ggtagaagaa gtgctgacgg
     2401 tttgcaacgt gaacgatttg ttttatttaa tcaatttaaa atcgatggaa aagctgatat
     2461 tccttttgct gaaatacaag tccatgagaa agccttaccc ttacttaata atcttgaaga
     2521 atgggttcga tattctctcc aacaattcaa tgaattagaa agcagttatt ccaaaaccat
     2581 gtttagatta ttaaaacaat acagaaccaa aggaattgcc tatttttcaa aagaagactt
     2641 tcatgaatta cttgatatcc ctaaaagtta tagagaaagt gatataaata aaaaaattat
     2701 aaagcctatt cgccaagaac taaccgcaat cttcaaaggt ctgacaatca aaaagaaata
     2761 cggaaaagga agaggaaaac ctgtcattgg ctatcaattc acgtttaaac ctgaaataaa
     2821 aaaagcagac gactttaata aacacgcacc aacaaaagaa gaacaaaata aagctttaga
     2881 actagttaat caacaaattt actctgaaaa agaccccact tcattacaag aaaaaatcaa
     2941 agaacagaaa cgaaaattag aacttttaca acaattagaa gagctagaaa gaaaacaaaa
     3001 taatctgaat aaagaaaata aggagattaa cgaacaaata ccagataaca attccgatat
     3061 tcccccagaa ttaaaaaaag gcttactaga taatcttcaa aacttattta aagaataagg
     3121 ggtttttatg acagataaaa ctatcaaaga attagcagat attctaggtg tttcaaaaga
     3181 taaagtgaag tatcaactga ggaaattacc tagtaatttt acctacaaaa aaggaaatat
     3241 tatctacctg aaaaaagaag cagtaacaac aattacaaag gttttatcag gtaatgagcc
     3301 gggtaactta cctagtgaat tacctgattc attacctacc gattacctac tcaaggagat
     3361 tgaaactaag aataatcata ttgaagaaaa agataggcaa attgaaaaac ttcaactagc
     3421 tttagaaaca caacaaaaat tactcgacca gcaacaacaa ctcaccctgc aagccaacca
     3481 acaaatcgag aaactgcagg aacaactaca gttgacttat acggaagaat cttcggaaaa
     3541 taaatcaacg actctttctg aagaaacaga atcgatagaa aaacaatcaa agacggagaa
     3601 aaaatggtgg caattctggc aataaaacca gcaatttaaa ttaataaaaa ttgctggttt
     3661 tattcttctt tttgcttttg cgagcagagc aacatgggcc catgttgcga tattttggtg
     3721 gcgccccaat ccccgttttt tcgttgaatc ttactcggac tgcactcgtt ttacagctga
     3781 tttttctgaa ttttgaaaga gcataaggaa acgtggtatc actttcttac gaaaggtgct
     3841 agataagctg tgcctatcac gtttctcaga aaaaaatttg ctatcacttt tttgccattg
     3901 tggctaggct atgtatagtg ttttggcgaa aaatagctat acaaatacta tatttgtatg
     3961 atatacataa attatatact gatacgaaag gaaaatttcc atggacattt tagttcgaaa
     4021 tatcaatccc aaaattatta caagaataga taaacgttgt caggaactaa caaccaaaac
     4081 gggcaaaaaa tggagtcgaa atcaatacct aaaaatttta atcgaaaacg attttgacca
     4141 cgaacttatg aattacaaaa aagatcaatt cgatttatta ttcgaaaaat ttattgccat
     4201 tcaagcagaa aatacgaaca tactaaatga ctatgttcac acaaacaacc aactcattga
     4261 aacacttatc ggaggaatat aacatgagaa aaacttctgt tcaaaaacac gtaacccttt
     4321 atcccagtca cgttgacgtt ttagattcca tcatcgaaaa aaatccagac gtcaacaatt
     4381 attcagaagc cattcgcttt ttatgtatga gttatgaacc tgctaccaat acaaccacaa
     4441 ccagtaacca agcaaaactc aatgccatgg gaaaagaaat ttctatcatg acagaaatca
     4501 tggcagaatt tgctgattta tatctaaaag atactggtgt tcttatcggt acaaattcta
     4561 aagtatatca agaagtgaaa gaaaaaattg aaaatcaact caatccttcc cgacgaaatc
     4621 aacccaaaaa tcgtcaaaaa gaaaccaatc aaacctttac ttctggaaat tttgacccaa
     4681 caaactttct aaaaagataa aaaaagaaac cgaaaaataa aaaaattcct cgatttcttt
     4741 ttagggatcg gtcttccagc aagatttgca agttggtacc aacttgcg
//
LOCUS       DAIGQM010000111         4629 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.117, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000111 DAIGQM010000000
VERSION     DAIGQM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.117"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..183
                     /locus_tag="NOA48_002604"
     CDS             <1..183
                     /locus_tag="NOA48_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0790829.1"
                     /translation="QRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLS
                     RTQRRFEGTLRYSLGY"
     gene            270..1124
                     /locus_tag="NOA48_002605"
     CDS             270..1124
                     /locus_tag="NOA48_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0790830.1"
                     /translation="MENSLYLVKEPNTHLRDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINEQKYYLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGELVEYY
                     LKEIGVGKENLTFKVENLNSFKGIIFETLSYDQDNLISELSRQTQVYKFLELLLNSAS
                     YLKEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKSDMGISI
                     KEYISEIKLSIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGAYRKRRL
                     GLGIINGE"
     gene            1221..3470
                     /locus_tag="NOA48_002606"
     CDS             1221..3470
                     /locus_tag="NOA48_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0790831.1"
                     /translation="MYKNNEMNIIYRSENQQFHLFNQEISYIFKISDDGKLLHLYYGE
                     NLPDNDYTHLIEMHHRPMTTYRKENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLTDFIYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3473..>4629
                     /locus_tag="NOA48_002607"
     CDS             3473..>4629
                     /locus_tag="NOA48_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790832.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
BASE COUNT         1624 a          661 c          851 g         1493 t
ORIGIN      
        1 caaagaaaaa cagttgagac tgttttttct tccttagaaa aattaggttg tcaaaatttc
       61 aactcacgtt ctgttaaagg gctagagagt agatttgaaa gcatattact ggcttacagt
      121 gttctattaa gtcgaacaca acgacgtttt gaaggaactt tgagatattc tttaggatat
      181 taaaattaac tagcaccacg ggtgatatta tgtaataata taaacatgat gaaacaaaaa
      241 ttatccaaat ctaacttagg aggactaata tggaaaattc tctatattta gtgaaagagc
      301 ctaataccca tttgagagat tgttacttta atttttgtgg atactcaaaa acagaaccta
      361 gacatagttt tggaccagct attcgagaac agtacttaat acacatagtc ttagaaggtg
      421 aaggttatta ttcaattaat gaacaaaaat actatctgaa aaaaggacaa ggttttgtga
      481 ttccaccagg agtatctact ttctatcaag cagatgaaaa aaatccttgg tcgtatgtat
      541 ggttgggatt aagtggagaa cttgtagaat actatctaaa agaaatcggt gttggaaagg
      601 agaatcttac ctttaaagtc gaaaacttaa attcttttaa aggaataatc tttgaaactt
      661 tatcttatga tcaggataat ctaattagtg aattatccag acaaacacaa gtttataaat
      721 ttttagaact cctcttgaac tcagcgagtt atttgaagga agggataatt actaaaaaga
      781 tgaatccttt tgttcgtcaa acaattgaaa taatacgtga gaatgcgtat caaaaattat
      841 ctgttaaaga tattgctgtc agtctatcga tacacgaaaa ttatttatca cgattgttta
      901 agagtgatat gggaatatca ataaaagagt atatcagtga aattaagctt tcgattgcaa
      961 atgacctact atcatcaact gaatattcaa ttcagcaaat cagtgataag ataggattct
     1021 caacagttca atctttttct aaagctttca agaaggccaa tggtgtttca cccggggcgt
     1081 atcgaaaacg taggttaggt ctaggaatca ttaatggtga ataaactaaa catttgattt
     1141 tgataaatat tcgttacttt aaacgcttac tatttatgta agcgtttttt ataatgcaat
     1201 aaagaagtgg aggagagcgt atgtataaga ataatgaaat gaatattatt tatcgatcag
     1261 aaaatcaaca atttcatttg tttaatcagg agataagtta catttttaaa atatcggatg
     1321 atggtaaatt actgcattta tattatggtg agaacttacc agacaacgat tatactcatc
     1381 taattgagat gcaccatcga cctatgacta cttatagaaa ggaaaacgat ttattatact
     1441 ccctagagca cttgaaacaa gaatttcctg aatatggtac aacagatttt agacatcctg
     1501 ccatttcact actacagaaa aatggctctc gtctaacaga ttttatctat caagggtacg
     1561 aagtggaaga aggaaaacca aaattagaag gtttacctgc tacctatgtt gataataatg
     1621 atgaaagcaa aacattgaaa gtttatattt tagattcagt tacaaatgtt caagtagaat
     1681 tattatatac aatttataga gattatcctg ttattactcg tagcgcgcga gttatgaata
     1741 aaggaaaaga tattcaaata atcgagaata ttagcagttt atcattggat ttacccgatg
     1801 caaattatga atggcaacaa ttatctggtg cttggggtag agaaagaact attaagtcgc
     1861 gtactttaca acaaggaatt caatcaatcg aatctactcg aggtatttca agccatcagc
     1921 ataacccatt tgttacttta aaaagaaaaa atactgatga aaatcaagga gaagctattg
     1981 gtgcagcact agtttactca ggaaacttct taattcaagc agaagtagat acatgggatg
     2041 ttactagact acaagttggc atcaatccat ttggatttaa ttggaaactc aatccaggag
     2101 aaatatttac agcaccagaa gcgattctgg tttattcaag taagggttta aatgccatga
     2161 gtcaaacttt tcatcaacta tttagaaaac gcttagctcg tggtaagtgg cgagaaaaag
     2221 accgtcctgt cttaattaat aattgggaag caacatattt tgattttgac gaagaaaagt
     2281 tggtaaatat tgctaaaaaa gcatttgatg ttggtattga attatttgta ttagatgatg
     2341 gctggtttgg agaaagagaa aacgattgtg caggattagg agattggcat gtaaatccta
     2401 aaagactacc tagaggaatc ggcagccttt cagaaaaaat tcgtagtttt ggtatgaaat
     2461 ttggtttatg gtttgaacct gaaatggtga ataaggatag tgagttatat cgcacacatc
     2521 cgaattggat tatttctaca cctaatcgaa aacctaatca tggtaggaac caatatgtat
     2581 taaattttgg gttagatgag gttgttgaaa atattttcga tcaaatgtgt aaaatcattg
     2641 atgaatcaaa cttagattac attaagtggg atatgaatcg tccattgact gatgtatttg
     2701 acagtcactt gtcagcagat caacaaggag aagtattcca cagatatgta ctaggcgtat
     2761 atcgcttata tgaaaaactt ataacaaaat atcctaacat actatttgag tcttgttcat
     2821 caggtggtgg gcgctttgat cctggaatgc ttcactatgc acctcaagct tgggctagtg
     2881 atgattcaga tgcaattgaa aggttaaaaa ttcaatatgg aactagtatg ctgtatcctc
     2941 tttcgtctat tggtgctcat gtatcaattg ttccaaatca tcaaacaaac cgtataacac
     3001 ctataaaaac tagaggaaat gtagcttttt ttggtgcatt tggatatgag cttgacttaa
     3061 atgaattaag tgaaggcgat ttgaggattg taaaagaaca aattgccttt tataaaaaat
     3121 atagaaccat aattcataat ggtacttttt atagactatt atcaccattc gatgatgata
     3181 atcaaaccgc gtggatggtt gttagtcatg ataagaaaac ggctattgtt gctcattata
     3241 aaacattaaa tgaggtaaat gctccttacc gccgactgaa attaaaaggg ttagataatg
     3301 acggacttta taatgtagga caaaatagtt tgcgatctgg aatggaattg atgagagcag
     3361 gactagtctg ttcagatgca tctagtggac aaataaatga tcagaatcga cgcccagaaa
     3421 catttgattt tgattccaag atttgggtta taacacagga ggaaaagtag agatgaataa
     3481 ccaaaaaagc ttacttcaaa aaggagcaat cttaagtatt tcactaatgt taacaagctc
     3541 tcaagcaatt aatggtgtta ttccacaaat gaaacagtct ttggggatat cacaaagtca
     3601 aagtgaactt ttaggaactg caccaagtat aactgttatt ttgtttatct tattatctag
     3661 ttactttgcc aaaagaatag gaatgaaaaa gacaataatt ttaggtttat tattagctgg
     3721 tataggagga attattccag tatttacagc taccttccaa accgttctta ttagtcgagt
     3781 aatattaggt gccggtttag gagtatataa ttcattggct gtgacatata tcagctcttt
     3841 atactctggc aatactagag caacgctatt aggtattaga aattcaatgg aagctttagg
     3901 tcagacaatc cttatttttc ttgctggagt tttagtgaac attaattgga cggcttcgtt
     3961 tttagtctat gcaattgcgt ttcctgtagc tctcttattc gcgctaaaag ttcctgaaat
     4021 tagagatgaa aatagtgaca tacctgaaaa tcatgtaaaa gaaaagatga atccaatggt
     4081 ttttgcccta gttctatttg caatcttact cgtaatgaat agtattgcta tttctgtacg
     4141 atttgcatca attgcaactg aaattaaagg ggtaaacttt aatgctagta actatttagc
     4201 tctaatgcct atcttaggaa tactagcagg atttatgttt ggaccaataa ataagtggat
     4261 aggaaaagga accctatact tgggaattat attctttata atttcaaatt tgttaattgc
     4321 tgtgtcaaac ggtaatatga cgttcctgct aacgggttta tttttatcaa gtataacagg
     4381 atcatggtgc ttcccattta tctttagtaa cttagataaa gtcactacaa agaatacaat
     4441 taattttgct acttcattga tttttattgg ctgtaatatt ggtaatttta tagctcctat
     4501 tgctatgcaa ttagcacaat ttctaacaag aagtacaaat ttgactgctc cattttttgt
     4561 attcgcagga atatttattg tgatcctatt tgtaacattt tttgcgacaa ataaaaaaaa
     4621 tactagagt
//
LOCUS       DAIGQM010000112         4461 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.118, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000112 DAIGQM010000000
VERSION     DAIGQM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.118"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            574..1008
                     /locus_tag="NOA48_002608"
     CDS             574..1008
                     /locus_tag="NOA48_002608"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790833.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="NOA48_002609"
     CDS             2298..3221
                     /locus_tag="NOA48_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0790834.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="NOA48_002610"
     CDS             3237..3776
                     /locus_tag="NOA48_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0790835.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DAIGQM010000113         4430 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.119, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000113 DAIGQM010000000
VERSION     DAIGQM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.119"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(543..2048)
                     /locus_tag="NOA48_002611"
     CDS             complement(543..2048)
                     /locus_tag="NOA48_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0790836.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="NOA48_002612"
     CDS             complement(2045..2731)
                     /locus_tag="NOA48_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0790837.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQFKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOA48_002613"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOA48_002613"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCI0790838.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          918 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgaattggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAIGQM010000114         4386 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.120, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000114 DAIGQM010000000
VERSION     DAIGQM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.120"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            2..74
                     /locus_tag="NOA48_002614"
     tRNA            2..74
                     /locus_tag="NOA48_002614"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="NOA48_002615"
     tRNA            78..150
                     /locus_tag="NOA48_002615"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="NOA48_002616"
     tRNA            155..225
                     /locus_tag="NOA48_002616"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="NOA48_002617"
     tRNA            238..311
                     /locus_tag="NOA48_002617"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="NOA48_002618"
     tRNA            323..394
                     /locus_tag="NOA48_002618"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="NOA48_002619"
     CDS             660..1853
                     /locus_tag="NOA48_002619"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCI0790839.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="NOA48_002620"
     CDS             1983..3455
                     /locus_tag="NOA48_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0790840.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="NOA48_002621"
     CDS             3538..4326
                     /locus_tag="NOA48_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCI0790841.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
BASE COUNT         1282 a          732 c         1021 g         1351 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 atagga
//
LOCUS       DAIGQM010000115         4375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.121, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000115 DAIGQM010000000
VERSION     DAIGQM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.121"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(83..1051)
                     /locus_tag="NOA48_002622"
     CDS             complement(83..1051)
                     /locus_tag="NOA48_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0790842.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1500..2906)
                     /locus_tag="NOA48_002623"
     CDS             complement(1500..2906)
                     /locus_tag="NOA48_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI0790843.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3127..3489)
                     /locus_tag="NOA48_002624"
     CDS             complement(3127..3489)
                     /locus_tag="NOA48_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790844.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENATMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDGLFGVITNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3493..3831)
                     /locus_tag="NOA48_002625"
     CDS             complement(3493..3831)
                     /locus_tag="NOA48_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790845.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3810..4229)
                     /locus_tag="NOA48_002626"
     CDS             complement(3810..4229)
                     /locus_tag="NOA48_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790846.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4222..4362)
                     /locus_tag="NOA48_002627"
     CDS             complement(4222..4362)
                     /locus_tag="NOA48_002627"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790847.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1251 a          978 c          603 g         1543 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgtgtc cagcgttgct cgactttatt tttttgctct
     1261 tttttcagtt tatttatttg ataactcaat aatagcactt ctctttagct atgcaaatat
     1321 ccaaaaaata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaggtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacaaaccg cctccggtac cgttgactgc acatcgtaac
     1501 taccactcga tctcatcttc agaacgctct aatttacgct gtgagacgtt ttgacgataa
     1561 aataaggttt tctcctgctc taacacttct aattcctcag aaagccccat atccttttct
     1621 gcaagaccaa aacggataga caaacgagtg atcgattttt gaaatgcgtt ttttaatcgc
     1681 tctaaacgct ggcgtaaaga gcgattttct tctttcagct ttttattttc cacttgtaaa
     1741 tctgctaatt gttttctacc agacaaatga cgctcttctt ccaatgtagc tacatactca
     1801 tttaattctg tattttgctc aagcatctgt aaatattgct cactcatgtt atcagcattt
     1861 ctcttggcat ttgttgctct cgtagctcgt tgatacaaat caacaaaatc attcccagat
     1921 aaatgatacg aaccatcagg aagcctcttg aaactttcta aaggaacaat atctttttgg
     1981 aaaatgaccg ccatctcttt ttttacattc agcatatttt tcttctcttc ttcaatcttc
     2041 actctctcag aagccaccag agccttttct cgctcatttt cttctctttg cctagaaata
     2101 tacctcaact catcagaaac gctctcacgc tcttttacgg ccgtttgacg caattctgaa
     2161 atctcgctca tgatttcttt atattcgtga acatctttga ttttgttagt accgactaac
     2221 tcacgctccc aaccaaaatc tgccatcaaa cgttcaattg actcaacttc ctgattccta
     2281 aaattattcc aaatcactcg accattctct ttatctgctc gtaaaccctg ctgttgcaag
     2341 gctttgttaa aacttggttg cttttgaaca ccccgtttat acccttcagc aacaggaaca
     2401 atattcaaat gcaggtgcgg acttacttcg tcattatgaa taacagcatt gtagacggat
     2461 aaattaggat tccgttcttt aaattctttg aaatattcaa ctaaaatttt gttggcaatc
     2521 actcgatttt gttctgcttg ttgttccgat atgccagtag aagaaccatc atcacgagta
     2581 gtacgaaaat catcaagagt accaatttgc acgataaatt ctcgctgtgg ttccaatttt
     2641 ttatccttgc gaacctttgc taaatagtcc tcgatttttc tatcggctct tttctgcttt
     2701 gcattatatt tttctacggc ttcaccgaat aattcttcat atttttcacg aatatttgtt
     2761 tgttctaaat agatattttc atccgatttt gtgaaatcaa tatgcttatg ccagtcattg
     2821 attttttggc tatcagttaa ctcacgatta ttatgagaaa tgcttgtatt ctttgttccc
     2881 tttttgaacg aaatactgaa ccccaagtta aaaccctcct tcggctgtcg ctaataaaaa
     2941 gagtgtaaac ctttctgtta ctctttgtca aagagtaaca ttttcctaat tgtgacatgg
     3001 ctgtcacaat tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag
     3061 gagccgaaag cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat
     3121 aatcgcttat cgtaaattca cgtcattaaa tattgacgta aatttactct cactcatctg
     3181 acttttctta ttcgttatca ctccgaataa gccgtcagat tcatcgggat aatctcgttc
     3241 gcttggcgct gatttttcat cagcaagcca ctcattatcc actgtttttt cgtgttgctg
     3301 atcgtcagaa attgacgata accaccgctc aaaatcagca aaagattcaa acccaaaacg
     3361 cttgcgaaga gccttgccca ttgtagcatt ttctttctca atcaagcgtt ttttctgttg
     3421 acgaagtttc gcttgttctt tttttaattt ttcttcttgc gctttaatat ctgctaaagt
     3481 cattcccata aactacatct ccttttcttt ggaattaata acggaaattt ggtttaactg
     3541 cataacatga ctcattaatt tcaaccaaaa ttctttttct gattcatcag ttgtttgcgc
     3601 taaatgctta tgaacaaatt cattagtcaa aactgaagat tttgctaaat cagcattgat
     3661 aaccgagttg agaacatcca taattcgttc aagcatttca ctataattat cttcatccgg
     3721 caaattcaaa taatcagcta accgttcata catcaattca attctatcga ctgtttcttc
     3781 tctcaaatca attttatcca tgtcacacct cacttccaga attgccacca ttttcgattt
     3841 tttaattctt gattttctag taacaactga tcgttttttt gttgctgaag caaagtcaat
     3901 ttttgttggt cacgaatcat ttccgttaat tcagaaatat gcctatcttt ttccgctaat
     3961 tgttcacgca aaaattcatt ttctttttct aacgggaaat cattgcctgc atcattgacc
     4021 ggtaaatcac cagtcaattg accacctttt gaccgataaa ttgaccgcac aacaccaatc
     4081 aattccttgt ctaacatgat aaccccatta tctttatacc gagcaaggtc ataacctgca
     4141 ttgaccagtt gattgcgcac tgtattttta gatataccca actcatcagc aaggtttttt
     4201 atggtcattt tttctggcaa atcagtcatt atcttctccg ttactttcag ctaccccata
     4261 aacatattta acagcatgct tagggataat gattggggaa tcaattttat tatttttcaa
     4321 aatcaactca tactgcgtta catcaagtaa cttaccggac atttttttgc tatcc
//
LOCUS       DAIGQM010000116         4336 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.123, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000116 DAIGQM010000000
VERSION     DAIGQM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.123"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..665)
                     /locus_tag="NOA48_002628"
     CDS             complement(<1..665)
                     /locus_tag="NOA48_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCI0790848.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENE"
     gene            780..2492
                     /locus_tag="NOA48_002629"
     CDS             780..2492
                     /locus_tag="NOA48_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790849.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            2495..4267
                     /locus_tag="NOA48_002630"
     CDS             2495..4267
                     /locus_tag="NOA48_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790850.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         1339 a          753 c          923 g         1321 t
ORIGIN      
        1 tgctcgtttt ctcttctttt attttgttgg cataagcctt caatataggt ttgtgcactc
       61 gttagaaaga gtgctttttc attcaattct gcatgggact gcatactttc tttaaatccc
      121 tctaattgat tttcaactac ataattacgc ataaatagaa ctgtttcttt caaaaattca
      181 tttccgtcca taattttttg tcgaagctgc tgttcatgct gctgatccat taactgtcca
      241 atcaataaat tgtggagaga ggcaatggcc tgatgacttt gggtgactga aaatccttca
      301 cgaacaagta attggatcat ttgctccaaa tgttctaatc gactcggaaa agcgggcaca
      361 gtattgattt ctaattctgc cccacaaggg aaacgtgtat aaaggtcata gtaattttcc
      421 atatactgca gcaactgttc attccaaggc aaagttggat ctggaagcgc taattcttct
      481 tccattgttt cagccatttt ttgcaagagc tgttgtttgt ttttgaaata ccaatataaa
      541 gcaggtgctt gaacatgaat tctgtttgcg atgtttcgca tggaaagctg cgaaagagct
      601 tgtgtttcag ccaggatatc aaaggcggcc tgaatgatga ttgcttgaga aagctttatt
      661 tccattttat caacctcgtg tattgcatta tctttttaaa catggtaaat tgttagtcgg
      721 tctaatttta cagtgttaaa ttagtcctgt caatttaaac aaaggggtgt aatcaacgaa
      781 tgaaattaat cttacgacat gcgaaaaaat ataaagtagc tgtttttatt tccttgctgt
      841 ccgtagcagt catggttgca gcagcattat ggcaacctaa gttactacag caagtattgg
      901 aagctattat tacagaagat aatgatgaaa tgaaaacaat tggtatttac ctgatcagtc
      961 tggctttgct aggattagcc gcaggtgtaa cgaacacgat tttctctgca aaagtagctc
     1021 aaggcgtaag tgcagatatc cgagaagaag catttcgaaa gatccagaca ttttcatttg
     1081 gaaatatcga acagttctct gctggaaatc ttgttgttcg tctaacaaat gatatcacgc
     1141 aaatccaaaa tttagtgatg atttctttgc aatcactttt tcgaattcca ttcttattta
     1201 ttggtgcctt cattttagct atgatcacga tgccgcaatt atggtggatc atcgtagcgc
     1261 ttatcgttac ggtatttctg attacggcac tttcatttac aaggatgggc aagcacttca
     1321 tgatcattca aaaactgatt gatcgtgtga atagcattgc aaaagaaaac ttactaggga
     1381 ttcgtgtagt gaaatctttt gtacaagaag aaaaccaatt gaagtcattc agcaaagtaa
     1441 gtgaggactt aacaaaacac aacatcatag tcggtacatt attttctgtg atgatcccgt
     1501 ccttcatgct ggctgccaat ttggctgtgg ttggggcgat cttttttgtg agcgatcttg
     1561 ttaaagatga tcctacgtta attggtggaa ttgcttcatt catgaactac ttgatgcaga
     1621 ttatgatggc aatcattatt ggcggaatga tgatgatgat gacttcaaga gcagccgtat
     1681 cgctgaagcg gattgcggaa attttagatg ctgaaccaga tcttacttat ttagacgttc
     1741 cagaacaaga gttgacgggt tctgtcactt ttgaccatgt ttcttttcgt tatcctggtg
     1801 aggatacaga tacgcttaaa gatatcagct tttctatcaa acctggagaa atggttggta
     1861 tcgtcggggc gactggtgcc gggaagtcaa cactagcaca attgatccct cgtctatttg
     1921 atccgacaga aggcaaagtt gaagtaggtg gtgtagatct tcgtcaagta aatgaaaaga
     1981 gtttaagaca aacggtttcc tttgttttgc aaaaagcaat tttattctca ggaacgattg
     2041 ctcaaaactt gcgccaaggg aaaaagaatg caacagaaaa agagatggaa catgcttctt
     2101 ctattgctca agcaaaagaa ttcatcgaaa agttatctga tcgttacgaa gcaccaatag
     2161 aagaacgtag cagtaacttt tctggtggtc aaaagcaacg tttatccatt actcgtggcg
     2221 ttatcggtaa tccaaagatc ttgatcctag atgacagtac gagtgcactg gatgctcgct
     2281 ctgaaaagct ggtccgagaa gcactcgatc gagatttgaa gggaacaacg acgattgtca
     2341 tcgcacaaaa aattgcttct gttgtcaaag cagaccgcat cttagtattg gatgaaggca
     2401 gattagtcgg cgaaggaacc catgaggaat tggtagctgg aaaccgtgtc tatcaggaaa
     2461 tctttgaaac tcaaaaagga acggaggagt aagtatgact gatctaataa aagcaagtaa
     2521 atttttctat cactatttga agcggtacaa actctccttt ttctttatct ttatcacagt
     2581 gatcattgct acctatctac aagtaaaggc acctcaatac atcggggaag cttttcaaga
     2641 attagctaat tacgtaggag gcttgatgca aggcgtagac gataaaagca aatttgtttc
     2701 tgtaatatgg aaactcttgc tgttttatgt actagctagt gcagccaact ttatctatag
     2761 tattttgttc acacaagtag tagggaagtc aacgaaccga atgcgtatcg gtctattcaa
     2821 caaattggaa aaattgacga tccgtttctt tgattctcat caagacggtg aaattttaag
     2881 tcgttttacc agtgacttag ataatattca aaatagtttg aaccaagctt tgcttcaagt
     2941 catcacgaat gctgttttac ttgtcgggat cttgatcatg atgttccgcc aaaatgtaga
     3001 gttagcttgg gctacaattg cttccactcc agtagccgtt ttgatagctg tcttgattat
     3061 ccgcaaagca cggaaatatg tggatcttca gcaagatgaa gtggggaaac taaatggtta
     3121 tatggatgaa aaaatcagcg gacaacgtgt catcatcaca aatggcttac aagaagaaac
     3181 gattgaagga ttcttagagc ataatcaaag tgttcgcgaa gcaaccttca aaggacaagc
     3241 ttattctggt ctactatttc cgatgatgca aggaatgtca ctggtcaata cagcgatagt
     3301 tatctttttc ggcggctggt tagcattaaa tggtgatttg gaacgttcgg tggcattagg
     3361 cttagttgtg acattcgtcc agtattcaca acaatattac caaccactga tgcagatttc
     3421 atctggatac agcatgatcc aattagcgat tacaggggca agacgattga atgaaatatt
     3481 tgatgaaaaa gatgaagtca aaccagaaaa cggtaaagca tttgatggtg ttgaaaaagg
     3541 tcttgcgttg cagcacgtag attttggtta ttctccagaa aaactagtct tgaaagatgt
     3601 ctcgatcaat gtggacaaag gagaaatggt tgctcttgtt ggtccaacag gatcggggaa
     3661 aacgacgatc atgaatctgc taaaccgttt ttacgatgtc aatgatggtt cagtagtcat
     3721 cgatggaata gatatccgag attatgatct tgatgcatta cgtagacatg taggaatcgt
     3781 tttgcaagaa tctgtattgt tctccggaac gatcaaagac aatatcacat tcggcaaacc
     3841 ggacgcttca gatgaagaag tcatcaatgc agcaaaacaa gcgaatattc atgacttcat
     3901 catgacgtta gaaaaaggtt atgatacaga gatatccgaa gaaaataact tattcagtac
     3961 aggtcaaaag cagttgatca gtattgctcg aacgatcatc acaaatccat ctttattgat
     4021 tttggatgaa gcaacaagta atgtagacac ggtaacagaa gcaaggatcc aaaaagcaat
     4081 ggatgaagca atcaaaggaa gaaccagctt tgtgattgct caccggctga aaacaatctt
     4141 gaatgcagat agaatcgttg tcttgcgtga tggggaagtc attgaagaag gcagtcatca
     4201 tgagttatta gcagaaaatg gattttatgc ggaactttat cataatcaat ttgtatttga
     4261 aagttaaatt aaaagaacct cgttataacg gggttctttt tatatatttt atgttgtttg
     4321 tttttataag gggcag
//
LOCUS       DAIGQM010000117         4298 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.124, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000117 DAIGQM010000000
VERSION     DAIGQM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.124"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..429)
                     /locus_tag="NOA48_002631"
     CDS             complement(<1..429)
                     /locus_tag="NOA48_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0790851.1"
                     /translation="MTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISV
                     FGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLYGIGDCI
                     FTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVL"
     gene            complement(487..1539)
                     /locus_tag="NOA48_002632"
     CDS             complement(487..1539)
                     /locus_tag="NOA48_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790852.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(1552..2490)
                     /locus_tag="NOA48_002633"
     CDS             complement(1552..2490)
                     /locus_tag="NOA48_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0790853.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(2940..3590)
                     /locus_tag="NOA48_002634"
     CDS             complement(2940..3590)
                     /locus_tag="NOA48_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790854.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(3690..4199)
                     /locus_tag="NOA48_002635"
     CDS             complement(3690..4199)
                     /locus_tag="NOA48_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCI0790855.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
BASE COUNT         1388 a          907 c          618 g         1385 t
ORIGIN      
        1 cagaacaagt aacaatggga aaagtagaaa gcctgcatag cctagcccag aacctgtatt
       61 atggatccaa gtcgatagat tccaagagct ttcattcgta ttgatactga ataacccagt
      121 aaaaatacaa tcacctatcc catataaacc aactgttgca acagcaagta ttgcaagtgt
      181 ttttgatgtt ccaacaaata ggtgatacaa cgcaggcaac gaaagaacaa aaaaaagtcc
      241 agatacaact gaccagacca agaaagcacg tctgactgga ctatctacgt caccaaacac
      301 actaattacg gtagtcattt gattcagttt gggataaaaa aggccaagga tatacggtgt
      361 cgataaatca ctaatcacac ctaataataa aaaataaaaa ccatattttg gcaaaaaaac
      421 gtaagtcaga tgttgttgac atctcactta cgcatccatt gattgaaaat ttcttagtaa
      481 aatctactag cctaaaaatt tgaagacttc ttctcgatca tacagtttaa atactttctc
      541 gcataaaaat tgagtaatta gtgccgcaaa aacagggatg actaaccaac aaagaacaac
      601 aagaaagcca tttagccctg catctaaaga agccaacgga ccaacaagtc cgaccacacc
      661 gaaaccagca gaagcaggcg tacctgaaat agaaaataga gcgacaggaa tagctgtaat
      721 cactgcacta actaaacaag gaataagaat cacaggtttt ctaaatagat taggcatcat
      781 catcttcata gcgcctaaag caatcgcaat tgtcacacct gacttattaa ccttccaaga
      841 gttcactact aaaacaaaag tggttgcagc tacgcccatc gcagccgcac cagcagaaac
      901 accatctagt tggattgcca ttccgattgc tactgttgaa ataggagaga taatcaaaaa
      961 ggcaaaggaa caaccaatca agatagacat taacagcggt tgtaaggtag tgaagttatt
     1021 aatcaatgat ccaattgcag aagtaattgc tgttacaaaa gggaataaat aaaaaccaag
     1081 taaacctgca cctacaccta caacaatcgg tgttaacaca atcgacactg acccaaaact
     1141 atttccaatc agtaaaatca gcccgacagc aatcgatgct gtcagcatcg tattaataat
     1201 atcgcctgta ccagcaccaa cgtaaacacc cgtttcaccc aaatcaggtg tgaatttgac
     1261 tacaccagaa ccaacaaaag aagctccggc tacaaccatc attctcatcg gatcaaatcc
     1321 aaattgtaag gcaatcaaac caccaatgat caaaggtgtt gctaattgaa aaataactgc
     1381 taactgtgcg atcgttaccg caaagggata cgcactaaaa tattttaaaa tagcacctaa
     1441 tactgcatta ggaatcaatc caataatgat tcctgttgct gtaccagcga ggactttatt
     1501 cagaaaaatt ttcggtgata ttttttgtga agtttccatt caatctctcc tttattttac
     1561 gttcaaacta tcttcttttg catggacaag ctcagtcaag aaatcacaat aaggcgtcgc
     1621 aacaccatat ttcttccctt ttctagaaat tgcgccattg atataatcga tttctgttaa
     1681 tcgatggttc ttaatcaagt cttgatacat tgaaggataa tgtaacccaa ttgtttccgg
     1741 gtcaaaacaa gattcacaat gtgcaatgac ttctgggaca tctagttcaa tcttctctac
     1801 tgctgctact ttggcaaact cattgacaat cgtcgccacc attttatgag cagtcgatgt
     1861 ttttcctagc tcagccatat taacgtctaa gattgtgcat agtccgttca ttgttccgtt
     1921 cacacatgct ttgcgataaa tagaatagtg aatattgtca gaaaaatgag catttaatcc
     1981 tgattcagac aatttgtctg ctaatttttt tgcagctgct tcttttccat cacctaaatt
     2041 ttgtaattct actgaaccac ttccaaataa tttgacctga ccaggacctt caagacctgc
     2101 cgtccacatg gtatttccaa tatagatatt ttccattggt acaaatttct caataatatc
     2161 ttcatgcccg ataccattta atagacataa gacctctgta tcttttttga ttaatgattg
     2221 gatatcctgc agcatttttt ccagctgcat cgctttggta aatagaataa tcagatcaac
     2281 ttgatcttct ttttctactt cggattgaag aacgattggt agttttgctt ctacctcttt
     2341 accattaaaa tttgcttgta atccatgttc tttgatttgt tggacatgtt ctgcccagcc
     2401 atcgattaat aatacttcgt tcccactttg gtgaagcatt aacccaaagc gacttcccat
     2461 tgcgccagcg cctgcaattg ctattttcat tgattcttcc tcctttttct ttctattata
     2521 cttatttgag aatcatttca caaccttgtt ttgttattct tctcttattt atcatgttta
     2581 tatccaccat tcaagttatt ttatcagcaa atcaataaaa ctggaataga atcccaattt
     2641 catcgtaaga gaaactagac tagcaataag aaaatagaaa cattcataga aaaaacctca
     2701 ctcctctgat tataaaagag ggggcattaa cctcgtgtat actaaaacct tccattcatt
     2761 cgatggatga ttttcttttt gtgaaaaaat attcattgta gtacgatgtt gcgcaacaca
     2821 gacggatggt attgcttatt atttattaaa atcgaacaat acacttattc aaaaacttct
     2881 ttcccagatt ttcttccatt tttacagtta taactagtat tatcatgaaa aatagccttt
     2941 tattgtctat gggaataata atttaaaatt ggtacttttt tattaattag ttcatcgccc
     3001 aataatctct ccagtttctt agcatctcct gactcaaccg gaattatcca agcccagtcc
     3061 aaataatttt ttaaaatctc atcatatttt gcaaatattt cattgccata ttccgtcctt
     3121 aaaattatat tttcagtgcc agacaagtga tttgtattga gttgataaaa aagatctcca
     3181 tctaaaaaaa tatcattaga agaagatttc cccacagtaa tgaccattcc atcagctcta
     3241 tgtgttacat acaaataatt gtatgacctc atttcaccta atgaatcaat tatttcttgc
     3301 cctttagctc taatatattg atctctatta cctatctcac tcttatttaa caaaagtttt
     3361 ttcatgtcaa atttaatcgg ctgttttatt tttgtaaatt cgcttctact actaatccaa
     3421 tccgagatta atttttcaac atgtcccaga gtaaactctg atttattcgc taaatacttt
     3481 ttttgttgta ttaaagacat ctttccccga agctcaaaat tgagcctaca tcgattctct
     3541 atctcttcaa aaagcatctt atcttcatca ttcttatatt catcattcat aaaaccaatc
     3601 cagctcctcg attaagataa tattttaatc tcatacaaaa actagctctc atcaaaacaa
     3661 ccattgtttt gatttctcat gaaatttctt tatacttttc tccgattata aattcctaac
     3721 cccttgagaa aattacgcat atatttatct ccgcaaggct taaaatttcg ttggccttct
     3781 tttctcaaaa atgccccgat ttcgcctttt gatggataga tttctgcctc agcaaaaacg
     3841 tctaaaatat catcagtggt catagacaag gcgattttta atttttttag caacacattg
     3901 ttgatatatt tgatttcctt gcttttttgc ggcgtgtcta ctatcggctt atctttttgc
     3961 ggaccacgtg ccaagagaat caggccattt aggaatgcgt caaaaacttg gttgttgatg
     4021 gttttttcat acacattatt ttctgcatta tctttgttct tatcctgtac tttggtcagt
     4081 accgcctgag cttcttcttt agtcagtggt acaccgccta gctcaaaagc tttaatcaaa
     4141 tccgtatctt tcaaatcaat cgcataacgc aatcgcaata acctatcatt gttattcatt
     4201 tgttcctccg aagtatttag tctttacttt cttacgtact ttttgtcttg ctaagatttt
     4261 taggatcaat gataaaaacc gcatcactta tgataagg
//
LOCUS       DAIGQM010000118         4292 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.125, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000118 DAIGQM010000000
VERSION     DAIGQM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.125"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(144..1055)
                     /gene="vanY"
                     /locus_tag="NOA48_002636"
     CDS             complement(144..1055)
                     /gene="vanY"
                     /locus_tag="NOA48_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI0790856.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(1483..2091)
                     /locus_tag="NOA48_002637"
     CDS             complement(1483..2091)
                     /locus_tag="NOA48_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0790857.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(2097..3128)
                     /gene="vanA"
                     /locus_tag="NOA48_002638"
     CDS             complement(2097..3128)
                     /gene="vanA"
                     /locus_tag="NOA48_002638"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0790858.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(3121..4089)
                     /locus_tag="NOA48_002639"
     CDS             complement(3121..4089)
                     /locus_tag="NOA48_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0790859.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         1183 a          997 c          762 g         1350 t
ORIGIN      
        1 ctctaattct tttgtttaag ttgtatcatt agtatagcaa tgtcctagtt aacgtgggtt
       61 ttaaattaaa aagctaacgt taccccaaaa gtgctagtac aataatgctg ttcattaatt
      121 tcgttggttt cattccgcca tccttacctc cttgaattag tatgtgttga tccgggaaac
      181 actgtcacaa ttacaccgtc tatattgttt cctgatatct cataacgaag attagtcggc
      241 acatgaatgg tggtattttt agtaacagga taataaaaga tctcatattt ttccccattt
      301 acactaacag aaatggtttt ttcttctttt aggtaatcca tatattcctc gagaacgaaa
      361 ttcttttctt tcataatcgc actatgtggt aaaccaacat agcgaatatg ccatagttca
      421 tattgaattc ctgttaactc tgttttgtcc tctggataac gtaaaatgaa cccgtatttc
      481 caagcatttt cttctatcca ctttccttca ggggctcgtt ccattttcgt caagcttgat
      541 cctacatcta gtgataaacc tgaattatgc tcactataac ctgctggtaa ggcatactca
      601 gcccccattt cttggtaaag cacactttgc tcatcaaagt ctcgatagcc actattaata
      661 ataaaatgac taacgccacc ctttacagca tcattgacca tctctgaaaa tttttgtgct
      721 atttcttttg acatataaat attactatca agcaacccgt atccatttat taattcgtca
      781 tgtttagata aattcacgat atctgacttc acactttctt ggcgaacagg atatttacta
      841 ttgattaata gcagatttcc ttgataaacc tgttcttctg taattgtttt ctcttgggta
      901 ttttcagaag tcccactatt ttctaaatgt tctttgggat tttgatcata attttgaaat
      961 tcgacttttt cctgagaaaa cagtgcttca ttaacgtagt cataacctaa gtatattaag
     1021 aataacaata acaataaaaa aaacaacttc ttcattttca gtctcctcct taactatata
     1081 gttggaagta tgaaatattt ctagaatctt ccccttaaac ggcacaatct cgtttgagat
     1141 tgtgccgttt tgccccgtaa attacagtca attatttcgc cctactggat ttactattat
     1201 caccaatgta gatgaatttt cataagtgat acccatgctg aatttaacga ggctgaactg
     1261 cctgttgaca atgggcggtg tgaaatacca cccctctatg cgatcagtct tattatcagg
     1321 ctatcttgcc gcagcgcacg cagataatga ccgcaatatc gctctgcctt acatcttcaa
     1381 tactatctac tatatataaa ttccctaaga accagttaca tacgtcgggt ttcctgccga
     1441 aagagttagc ttatatagtt tgtccgtgca acggttaaaa gtttatttaa cggggaaatc
     1501 aaaatagcta ttggggtatg gttcgtctct taatacatag tgccaccatt cgaggctata
     1561 tgcttcaaac ccactgtttt ccatgatgga gcgcaaacgt ctgcgatttt gcgcttcatt
     1621 gcatgatatt ccatttgccg catgatgaga gcgttcatcc ataaaatcaa atcggctccc
     1681 cattggtaca agctcacccg tgtctaatcg ataaagcgta agatcaatgg cactgccgcg
     1741 gctatggctt gattttgaag ccacgtatcc ttttgaaatc atctcagttc ggtcaatatt
     1801 gggataataa ctttcctttg tcaggttatt ttccggctgt gcagcccatt gcataaaaca
     1861 gtttacagca cgattaggac ggtaaccgtc ccatagaagc aatccgtacc cttgggtagc
     1921 agccagttct tttgccttca aaagcgattc agccaactcg tatgtcccta caatgcgatt
     1981 tacttcataa ccgtcaaccg gttttccggt gaaattatcc caagtggcat atttagcgtc
     2041 ccaacgaaca ccgtgtacta tttcatctaa aaaagtaaat cctatttcca tgcttatcac
     2101 ccctttaacg ctaatacgat caagcggtca atcagttcgg gaagtgcaat acctgcagcg
     2161 gccatcatac ggggataacg actgtatgac gtgaaaccgg gcagagtatt gacttcgttc
     2221 agtacaatgc ggccgttatc ttgtaaaaac atatccacac gggctagacc tctacagccg
     2281 agcgctttat atattttttt tgccgtttcc tgtatccgtc ctcgctcctc tgctgaaagg
     2341 tctgcgggaa cggttataac tgcgttttca gagccttttt ccggctcgac ttcctgatga
     2401 atacgaaaga ttccgtactg cagcctgatt tggtccacct cgccaacagc taacgcggca
     2461 ctgtttccca ataccgcaca accgacctca cagcccgaaa cagcctgctc aattaagatt
     2521 ttgctgtcat attgtcttgc cgattcaatt gcgtagtcca attcgtccgc gctattgact
     2581 tttttcacac cgaaggatga gcctgaacgc gccggcttaa caaaaacagg ataggtaaac
     2641 gtagctgcca ccggcctatc atctttatta ataacccaaa aggcgggagt agctatccca
     2701 gcatttttcg caacgatgta tgtcaacgat ttgtccatac aaattgctga gctttgaata
     2761 tcgcagccta caaaagggat accggacaat tcaaacagac cttgtatgga tccatcttca
     2821 cctgacttgc catgcaaagc tgaaaatgct acatcaacat ggttgatttc atattcatgg
     2881 ttctttttaa caagtaatcc gtgcattttt ttatccggcg agagtacagc tgaatagcaa
     2941 ttgtcgtttt cccattccgc gcaaggtttt tcgcacattt tccatacacc agatttcgta
     3001 attccaatgt ataacggctc gtatttttct ttattaatgt tagcggctat ctctattgca
     3061 gattttaccg atacgtcatg ctcctctgag caacccccaa acagtattgc aacttttatt
     3121 ctattcatgc tcctgtctcc tttcaaaatc caaacagttt ttaatggttt tttcaacggt
     3181 atcacgcaac gcttgctcgg tataataggc cgtatgcggt gtgattatca cgttaggcat
     3241 tctttgaagt ttaagtaaaa attgattatc aattggtttt tgggtgcaat cagagtagaa
     3301 aaactcttcc tctccttcca atacatccaa tgcggcaccg cccagtttcc cgttttctaa
     3361 tgctttaacc aactcatagg tatctacaag tggaccgcgc ccagtattga taagaaatgc
     3421 tccttgcttc attctctgta tttgttcgtg gctgataata tagtgcgtat ccgtattgag
     3481 cggcacatga agcgtaacga tatcgctatt ttgcagcaac tcatcaaacg gtacatagtt
     3541 tacctctata cttcggctgc gactataagc caacacttta catccaaatc ctcgcagccg
     3601 ctcaataacc gctttgccta tctggcccgt tcccaccaca ccaactgtca tgtcgctgag
     3661 taccttgcca cggtcgctgt ccaacctgaa atcatgtttt tccacagagc gcacaatcga
     3721 ttttacgttg cgtactgcca taagaattag catcatagta taatcggcaa cgctatccgg
     3781 cgagtacgcc acattgtcga cagtgatgcc cattctctta gcagcagttg tatctatatg
     3841 attgcagccg atgcttcggg tagaaatata tttcacaccg gctctcttca gcgcaagaag
     3901 aatagaggcg gaaatctctg atttatgtcc cacactgata cattgattga aaggcgcgga
     3961 tttggcgttg gattccgaca cgttggcgtt aattatcgtt gccataacgc caaagcgagg
     4021 cgaaagagca tggaatgcat ctgcctcatc ctgctcacat ccataaacag taatgccgat
     4081 gttattcata attaagacca accctttctg tgaaaggcac caaataaaac ggggatgcca
     4141 atggtaatct tgtcaaatct ttctctgaag aacgaaaacg gctcgttctt acggtattaa
     4201 gtctaccgtg taagaacgag ccgtttctta atattaaatt gttaatttcc taagaaaaag
     4261 taaagataac cttgagattt tcctaaaaaa tt
//
LOCUS       DAIGQM010000119         4116 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.126, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000119 DAIGQM010000000
VERSION     DAIGQM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.126"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            7..1197
                     /locus_tag="NOA48_002640"
     CDS             7..1197
                     /locus_tag="NOA48_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HCI0790860.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            1331..3520
                     /locus_tag="NOA48_002641"
     CDS             1331..3520
                     /locus_tag="NOA48_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0790861.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            3517..>4116
                     /locus_tag="NOA48_002642"
     CDS             3517..>4116
                     /locus_tag="NOA48_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0790862.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNI"
BASE COUNT         1468 a          640 c          745 g         1263 t
ORIGIN      
        1 ttccctatga acgattttac tacagaaatt ctaaagactc tagcgaacaa aggcgatttg
       61 aatgaattat tccgtgtcca tttggagaaa gcagtcaata cgcttctcaa aacggagtta
      121 acggctttcc tagattacga aaagtatgat cgcattggtt ttaacacggg taattctcgt
      181 aacggctcct atgaccgtac ggtcaagacc gagtatgggg aacttcatct ccagattccg
      241 cgcgaccgca atggtgagtt caagcaacag actgttcctg cttatagacg gacgaatgac
      301 acgttagagg agaccgtcat tcacctcttc cgaaaaggta ttaccatgtc ggaaatcgca
      361 gacttgattg agaaaatgta tgggcattac tacacgcccc aaaccatgtc caatataaca
      421 aaatcattta cagaagaggt aacggcgttt aatgggcggg agcttcatga ccgttatgct
      481 gctatttata tggacgcaac gtatattccg ttaaagcgga aaaccgtcgc caaggaagct
      541 attcatatcg cagttggcat tcgcccggac ggatcaaagg aagtattgag ctatgcgatt
      601 gcaccgactg aatccatcac gatttgggag gaaattttat tggaccttca agagcgcggt
      661 ttgaaaaatg tcctcctgtt catcacggat ggcttaaagg ggatggtagg agcgattagt
      721 cggttctatc ccaaagctcg ttttcaacat tgttgtgtac acgtttcccg taatatcagt
      781 cataaagtgc gtgtcgatga tcgtaaggaa gtctgtgatg attttaaaat ggtgtatcaa
      841 gcctcatcta aagaggtggc gttggaagca cgtggtactt ttgcggaaaa atggaaaacc
      901 agctatccaa aagtggttga atcgattctt tcgaacgatc acttgctcac tttctatgat
      961 ttccccttgg ccatacgcaa gagtatttat tctacgaact tgattgaatc ctttaataaa
     1021 caaatcaaga aatacagcca ccgcaaggaa cagttccaaa atgaagagtc gatggaacgt
     1081 ttcttagtct cgtcttttga tacttacaac caaaaattcc taggtcgcag tcataaaggt
     1141 ttccaacagg ccgaaggcga gctcgaacaa atgctaagcc aactgattga gaattagaaa
     1201 caatctgcag tagggaagaa tcatttacac aaaattattg acgctccctt ataatgagaa
     1261 cttttactaa cataatttat gataaactta ctatataatc atattaatta aatagttagg
     1321 agatctgctt atgtttatat ctactcttca aattcgaaat tttagaaatt atgaatccga
     1381 aatctttcga ttcgataatg agacaaatac tattataggt gagaatgatt cagggaaaac
     1441 caatgctctt actgcattga gaatcttatt agatgatagt tattactata gtagtaaaac
     1501 actaaaagaa tcagattttt ttcatggaat tcaaaatggg tggcaagggc attggattat
     1561 tatctctgcg acatttgaag gaatcagcga agaagaattt gacaatgaga tttgtgcttc
     1621 catttcttta aattctgaaa gtcaaacaat cttagaagaa ttgatttcaa atgcagataa
     1681 aggtgtaggt agtatttctc tatttattag acctaacaaa gctattagaa agcaattatt
     1741 tgatatttcc actgaattag actctcatca atttaacgaa tttagaaatt ctattcgtct
     1801 atccgactat gaattttact acacatctaa atcaaatcta aatttctgta tcaatgaaaa
     1861 ttatgataaa ttggtaggaa gactcaatga caatatagct agtaatcctg aagaagacga
     1921 tgaagctctg ttgggctcaa gaattgacat gtcagatatt ttcaagcata tttcggttgt
     1981 ttatgttgac gctcttcgag atgttcttag agaaatgaaa aacaatcgaa acccagtcaa
     2041 aagaatcatg gaaacaattg aatcaaaaat atcatcagat aatgttgagt cattaaaaac
     2101 aattatacag caattaaatg agactattac cagtgttcct gaaattagga aaattggcga
     2161 aaatattaat cggcaactaa atagcataat tggttcagtg tattctccta atcttcttct
     2221 ttcctcaact atgtcagatg atatgggttc tttagcaaaa tttctttcaa tgaagccaga
     2281 acaaaatatc gacttagact tactagggtt aggacatcta aatatgattt atttagcttt
     2341 gaaaatagtc gaatttgaag cgtgtcgttc aagagaacta cttaatatta tgttgattga
     2401 agaaccagaa gctcatattc atcatcatat tcaaaaaact ctgttcgaag gattaaatct
     2461 tcaaaaaaac tatactcaga ttctcatgac cacacattct gtacatttag ctgaagtgtc
     2521 tgaaatatct cggatgaatg tattaaaatc gtttaatggc aaatctatcg ttatgaatcc
     2581 agcaaataat ctgaactcat ttgctaaaga aaagttaaaa aagaacaatc taaatctaat
     2641 aaacgcagta gagagatatt tagatgttaa aagaaatgga ttgctttttt ctaaaggtgt
     2701 tatcttagtt gaaggagatg ctgaagaaat acttattcct caaatagtaa aaaaattatt
     2761 tggtataaac ttagacgaac ttggaatagg tttgattaat gttggtagta cttcgtttga
     2821 atatatcgct agcttgtttg acgatgatag aatacagaga aagtgtgcta ttgtaactga
     2881 tttagatgaa caggcaatcc catcagaaca tcgattgtat aaaagcactg cacaagagaa
     2941 aggtcaagca agaaaagaaa aattatcctc cctttttaat gaaaacaatt gggttaattg
     3001 tttttatgct aatacaacat ttgaaattga gtttttagat gtgaataaag aaaatattct
     3061 aacttatgtc agtccaatta tagatgacgc attcaaagat aaaaaaacaa taactgctta
     3121 taaagaagaa atacaaagtg aacaatattt agaaagaaat ttagcgatgt taaaactagc
     3181 caatcatgtt ggtaaggggt ggtttgcaat tgagttaggt gaaaaaattg actttttaat
     3241 caaaattcct aagtatattc ttaatgctat tgcttttgca tgtcaggaaa tagtagatct
     3301 ctcaatttat aaaaaaattc tactccatac aatcgacttg tacgaggaaa ctacagaatt
     3361 gtcagcttta tcagctagtt taaaaacaag tgatacagct gatttgaata tagcaataat
     3421 ttctttatta gagtactttg gtaaagatga ggatgttgtg tatctaatca atcagataga
     3481 aaattacaca aaaatacttt atgctgaggt ttcaaaatga caaatatctt cgaaaaaatc
     3541 gtaaatgatt taaatttaga acaaaaagat gttgtggaaa gtgaagataa cctttatgta
     3601 aatgcatgtc ctgggagtgg gaaaacaagg gtacttacaa ggaaaattgc ttaccaagca
     3661 attaaacacg atggatcact aaaaagaata attgctatca catacactaa tagagctgct
     3721 gaagaaatta aggaacgcct aagtttactt agtatagatg atgatattaa tatttgggtg
     3781 gggacaatac atcagttttg tcttgaattt attatttatc cttttaaaat gaatctctca
     3841 agagtatcaa aaggatttac aattattgat gattatactc aaagagctta cgtcagccaa
     3901 attaataata tgctgaattt aaatctcaaa acgtatgaac tgaacaaaat tgatttgtca
     3961 ctttctcatg attttaaaat taatgaagtt cagtatactc aagtttctga aatgtatcac
     4021 actatgttgg aaaaaaataa agaaattgat tttgatatga ttttactagt agcgtataaa
     4081 attttaactg taaacagtaa cgttgcacgt aatatt
//
LOCUS       DAIGQM010000120         4039 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.127, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000120 DAIGQM010000000
VERSION     DAIGQM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.127"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            179..775
                     /locus_tag="NOA48_002643"
     CDS             179..775
                     /locus_tag="NOA48_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0790863.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="NOA48_002644"
     CDS             899..2698
                     /locus_tag="NOA48_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0790864.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESMKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="NOA48_002645"
     CDS             complement(2976..3188)
                     /locus_tag="NOA48_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790865.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="NOA48_002646"
     CDS             3650..3799
                     /locus_tag="NOA48_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790866.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
BASE COUNT         1188 a          689 c          711 g         1451 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagta tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaata
//
LOCUS       DAIGQM010000121         3970 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.128, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000121 DAIGQM010000000
VERSION     DAIGQM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.128"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..356
                     /locus_tag="NOA48_002647"
     CDS             <1..356
                     /locus_tag="NOA48_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0790867.1"
                     /translation="EIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKS
                     LEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGN
                     VFKIEYTKKRQRLAY"
     gene            591..827
                     /locus_tag="NOA48_002648"
     CDS             591..827
                     /locus_tag="NOA48_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790868.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            834..2786
                     /locus_tag="NOA48_002649"
     CDS             834..2786
                     /locus_tag="NOA48_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0790869.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOA48_002650"
     CDS             complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOA48_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0790870.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3585..>3970
                     /locus_tag="NOA48_002651"
     CDS             3585..>3970
                     /locus_tag="NOA48_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0790871.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVE
                     PSKPEQREMLLDALLEISDSDPLLRY"
BASE COUNT         1415 a          640 c          697 g         1218 t
ORIGIN      
        1 ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta
       61 ccgaatctga acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattggaac tcgaacaaga ggaaagcata agatttcaga
      181 attgttctct gttccctctt tatcatggaa gtgcaaaaag taatataggg attgataacc
      241 ttatagaagt tattactaat aaattttatt catcaacaca tcgaggtccg tctgaacttt
      301 gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca tattaagtag
      361 ttcagttttg gagtacaaaa agtgaaaatg taaacctaaa tgagtatcaa attgcaactg
      421 aatttgatac tcgtttttta ttgttaaatc aacgtttgtt gttaatttac accacaaaat
      481 gtaagttaaa atgtatataa aaatgcgaac gtgaaataat tattgtagga atgcaaattg
      541 gtgtgttaaa atggttacaa tttactaagc aaaaaggggt gcattttcct atgcaatttc
      601 ttgagccaaa aaataagaac gctaagtctg tggattggga aatatcagag caagtaaggg
      661 tgatagttaa gcaatacgct gaatatgcag agcgtactga aagcgaagca gtggatgaat
      721 tcttattgaa cattttagac gataagaagt ttattgaatg gattgccaac aagcgaagta
      781 ataagcggat tgttgaaaaa atgggtatca aagatagagt gggttgatag acaatgacca
      841 agcttaaaag attagccacg aaggaagatg aaattgtaga tgttaaaatt ccgatttcaa
      901 acgaagaatt aaaagatagg gctaaacaat atgatttatt aactccaaaa cgatttgcaa
      961 caaggtataa caaaatgttg ttcttgccaa cgtcttttaa atggaacggt tctgaatatc
     1021 ccattcaata taattactgc atcaatccgt tttgttgtaa ttttgggaaa gaacagcaca
     1081 aattcaaaga tgtaaaaggg aaaccaagtc gatataaaat gactggtagt tccaaagata
     1141 aaggtcataa aggtatgtac tgcaatgaca atcctattgg cagaggtgta tcgcaaaact
     1201 gtacagtaac ccctttatct aattggtctg ttgttgaaga aattaaacgc cttatagaaa
     1261 tcaatagcat ccaagatgtt gagccagatt atcaatttca taaagaaggc tgctcggaag
     1321 aagaatcaac cccattcaat gagccgaagc aattttacaa aagggggaaa agtaggggca
     1381 aatctcaacg ctatcaatgt aaggcgtgta agaagttcac taatgttcta ccaaaaagag
     1441 aagaaaccac tacttatcac caacaaaaga acaccattct tccaatgttc gctaagatgg
     1501 ttgttggaag ggtttcagtc agtcgtactt gtgatatttt aggaattgga gttggaacct
     1561 actatcataa gctggagtgg ctgtataggc gttgtttgga gtttttagaa cgatatgaga
     1621 cacaacccct tcaaacaaag aaatttaacg agatgtggct taatacggac aagatgcact
     1681 actacctaaa taacgtccgt aagaaaggac aaggttcaaa gaaatatacg gggtttgaag
     1741 accttaatat gcaaacgtat atagttgtat ctgctgaggt cttatcaaga tatgtgttcc
     1801 gttctgatgt tgcctatgat tggaatattt caatggatga attaaatgaa gatacaagaa
     1861 aattcaaaga agaccatctc aatactttta gtcgtaaaaa tgataggtta gattggtctt
     1921 attatccaca agaaccatcc gctaacgata gcgaaaatag gaatgcttat cttcacgaat
     1981 tagggaaaat tactaatagg agtagatttg tcgatggttt aaatgttgat gctccttata
     2041 ctacaactgc tcactattgg ttaattaaac aaatggttaa tgccgacgaa tggcgaatga
     2101 ttagtgatga tgacttctct attagaaacg ccttttatag agtattcacg aaagaattaa
     2161 ggttgagcga tgcacatcat tttatttgcc aagttaacaa gacgaaaagc agaaaacaat
     2221 gcttaaaaga attcggacaa gcaaaagcag aactgctcga ttggggagat atcagaggat
     2281 tcaaaacaaa gtttctacgg actttggcat ctcattatct aactgaatta ctaacaagtc
     2341 atcaattcca cgaagaggct attagtaaag atggagaaag atatcgcaaa tatgccgata
     2401 accctatcaa acatccatta gccactaagg ataaaggatt ttattcagtt gattgtagaa
     2461 cggatttatc tgctctggaa ccaaacgaaa tcgcaaagat gctattaaat gttaatgacc
     2521 attcgaccaa tagctttatt caacagataa gacgttatat atcatctctt gaaagaccat
     2581 taacaacagc tcgtggtgat aagaagagct atatttacgc taacttcaat ccgaagtatg
     2641 ctcaatttgc gattacaatt ctaagaactt actacaactt ttgtcgccct tttaaatcag
     2701 cggataaaaa ggttttgaca cctgctcaaa gattagggat tacagataaa caatttgatt
     2761 ggaaagatat aatttatttc aaatgacaaa aagagcttgg agtaatccca agctcttgtg
     2821 ctttatcttt actgttcttc ttcaattaac gcacccgtta actcaataag ttttttcttt
     2881 catatacatg aaaatagtag ttatacggat ttttatcatt ctttatccct ttttgggcaa
     2941 atacctcatt ccattcctca taattcactt ctggaaaaaa agtatctcct tcgaattcat
     3001 gatgtatttt tgtgatgtac attttctcaa cataagggaa aaacaaatta taaatctgtt
     3061 ctcctccgaa aataaaaatt tcttcttcgt ttttacataa ctcaaaaaca tcttctattg
     3121 aatgaacaat ttcacaacca ttaaaggtaa accccttatc tctcgtcaga ataatatttc
     3181 ttctgtcagg taaggctctt ccgattgatt caaggttctt cctacctaat attatcggat
     3241 gtccctttgt agtattttta acatattccc agtccttggg aatcctccaa ggaatgtcat
     3301 tctctttgcc aatcactcta ttcttatcca tcgcagcaat caaagaaact ttcatttata
     3361 acacagcctt tttaactaat ttaccatcta atttcttatt tctatcaaaa aaccttttct
     3421 cattatcctg cccgttagtt gaataagcaa ttttttctat aagttatatt atcataatac
     3481 cacaaaatca caaattttca ttcaattatc attttcaatt gcattttata aatcattttg
     3541 tatgtaattt ggtatgtaag ttaaaatgaa aaaagtagtc cattttgaag tacattttgt
     3601 cattttgtac tccaaaactg aactacttac ttgcatatat acgcctttat agtggagtac
     3661 tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt acagaaatgt
     3721 atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga gaaattgtta
     3781 ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa ctattgccac
     3841 agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa ccgagtaaac
     3901 ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt gatccgcttc
     3961 tacgatatta
//
LOCUS       DAIGQM010000122         3956 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.129, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000122 DAIGQM010000000
VERSION     DAIGQM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.129"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..156
                     /locus_tag="NOA48_002652"
     CDS             <1..156
                     /locus_tag="NOA48_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCI0790872.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="NOA48_002653"
     CDS             175..1452
                     /locus_tag="NOA48_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790873.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="NOA48_002654"
     CDS             1462..2118
                     /locus_tag="NOA48_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0790874.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..3494
                     /locus_tag="NOA48_002655"
     CDS             2118..3494
                     /locus_tag="NOA48_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0790875.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3624..>3956
                     /locus_tag="NOA48_002656"
     CDS             3624..>3956
                     /locus_tag="NOA48_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790876.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1594 a          424 c          693 g         1245 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat aatagcggtg
     2761 tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt catacagctg
     2821 ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca ttctttgtaa
     2881 aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat ataaattgga
     2941 gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa tctatatcag
     3001 gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca ggagttgtag
     3061 tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca gtattactat
     3121 cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg gtatttatat
     3181 caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac aagcttggga
     3241 ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa caatctgcat
     3301 ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta tcaagtttag
     3361 atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt ttagtacttc
     3421 ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa gaattattaa
     3481 ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg taatataaac
     3541 cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat ttttctaaaa
     3601 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gctgagaagt
     3661 tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg caagatgttt
     3721 taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg aataaccatt
     3781 tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga aacggttatg
     3841 gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc agagaccggg
     3901 aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DAIGQM010000123         3876 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.130, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000123 DAIGQM010000000
VERSION     DAIGQM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.130"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(716..3865)
                     /locus_tag="NOA48_002657"
     CDS             complement(716..3865)
                     /locus_tag="NOA48_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCI0790877.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DAIGQM010000124         3791 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.131, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000124 DAIGQM010000000
VERSION     DAIGQM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.131"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..411
                     /locus_tag="NOA48_002658"
     CDS             <1..411
                     /locus_tag="NOA48_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790878.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            521..571
                     /locus_tag="NOA48_002659"
                     /pseudo
     CDS             521..571
                     /locus_tag="NOA48_002659"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            605..1981
                     /gene="tet(L)"
                     /locus_tag="NOA48_002660"
     CDS             605..1981
                     /gene="tet(L)"
                     /locus_tag="NOA48_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI0790879.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2577..2888
                     /locus_tag="NOA48_002661"
                     /pseudo
     CDS             2577..2888
                     /locus_tag="NOA48_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            3023..3670
                     /locus_tag="NOA48_002662"
     CDS             3023..3670
                     /locus_tag="NOA48_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI0790880.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1254 a          507 c          697 g         1333 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca gggttcaatt
      541 aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta ttggagggtg
      601 aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt taatttggct
      661 ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct cattacctga
      721 tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca cagcctttat
      781 gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat taggcatcaa
      841 aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg ggtttgttgg
      901 ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg gtgcagctgc
      961 atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa
     1021 agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc cagcgattgg
     1081 tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta tgataacaat
     1141 tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa aaggtcattt
     1201 tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt tgtttacaac
     1261 atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca
     1321 tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata taccttttat
     1381 gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg tctctatggt
     1441 tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa gtgtaattat
     1501 tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac ttgttgatag
     1561 aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta gctttttaac
     1621 tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg tatttgtttt
     1681 aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta gcttgaaaca
     1741 gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat cagagggaac
     1801 aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa ggttgttacc
     1861 tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt tttcaggaat
     1921 cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa gggatttcta
     1981 aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt ttataacagg
     2041 aattcaaatc tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc
     2101 tctcttgtat cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca
     2161 ataaaaattt tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata
     2221 aaaattggca agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc
     2281 tgtcccttgc tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag
     2341 agggcaggtt tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat
     2401 ggttttggtc ggcactgccg acagcctcgc agagcccacc tttacgaagt aaagtatagt
     2461 gtgttatact ttacatggaa gttgtaccga aatattgtgt tgtgaagtct atataatttt
     2521 aaaattatga agtctatata cgtgcgtaaa gatatttaaa gagattaaaa ataataaaaa
     2581 taaaaattga attaaaaaga gatatggttg attattggaa cgattgtttt aatgatttac
     2641 atatattaca accagattgg aaaactatcg aacgtacttc tgatagagca atggttttta
     2701 tgttgttgaa tgatgaagaa gaatggggaa aattagaaag acgtactaag aataaatata
     2761 aaaaattaat taaagaaata tctctaattg atttaactga tttaatgaaa tcgactttaa
     2821 aagcgaacga aaaacaattg caaaagcaga ttgatttttg gcaacgtgaa tttagatttt
     2881 ggaagtaaag taactttgtt ttatacaaaa tgttacttta gtataattaa cgtttaagag
     2941 gtgacacaat atatgaaaaa atcagaggat tattcctcct aaatacaaag agataagatg
     3001 aaatttagga ggaaaattat atatgacttt taatattatt aatttggaaa cttgggatag
     3061 aaaagaatat tttaatcatt atttcaatca acaaacaact tacagtgtta ctaaagaatt
     3121 tgatatcact ttacttaaaa gtatgataaa aaataaagga tatgaactgt atcctgcttt
     3181 gatttataca attgtaaata ttataaatca aaataaagta tttagaacag gaattaatag
     3241 tgagggaaat ttgggttatt gggaaaaatt aaacccttta tatacagtct ttaataaaga
     3301 aactgaaaaa ttttctaaca tttggacaga atcaaatgtt agttttaatt ctttttataa
     3361 tagttataag agtgacttac ttgaatataa agataaaaat gaaatgtttc ctaaaaaacc
     3421 aatacctgaa aacacagttc ctatttcgat gattccttgg attgatttta gttcatttaa
     3481 tttaaatatt ggtaataata gtagattcct attgccaatt attacaatag gtaaatttta
     3541 tagtaagaat aataagatct atttaccagt ctcattgcaa gttcatcatg cggtatgtga
     3601 tggttaccat gtttcattat ttatgagtga atttcaaaat atagttgata gtgtaaatga
     3661 atggatttaa atctaaaata actttcataa acttaagtaa ttatgatatt tataagttta
     3721 tagcaactac catttttggt tgctggtgtt ttgattttga atttggtttt gaacttatgg
     3781 actgatttat t
//
LOCUS       DAIGQM010000125         3718 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.132, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000125 DAIGQM010000000
VERSION     DAIGQM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.132"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..352)
                     /locus_tag="NOA48_002663"
     CDS             complement(<1..352)
                     /locus_tag="NOA48_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790881.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(612..1160)
                     /locus_tag="NOA48_002664"
     CDS             complement(612..1160)
                     /locus_tag="NOA48_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790882.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1161..2018)
                     /locus_tag="NOA48_002665"
     CDS             complement(1161..2018)
                     /locus_tag="NOA48_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0790883.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2304..2591)
                     /locus_tag="NOA48_002666"
     CDS             complement(2304..2591)
                     /locus_tag="NOA48_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0790884.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(2581..2910)
                     /locus_tag="NOA48_002667"
     CDS             complement(2581..2910)
                     /locus_tag="NOA48_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0790885.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="NOA48_002668"
     CDS             complement(2987..3259)
                     /locus_tag="NOA48_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0790886.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="NOA48_002669"
     CDS             complement(3259..3522)
                     /locus_tag="NOA48_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0790887.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1090 a          754 c          473 g         1401 t
ORIGIN      
        1 atgttcttac tgcctcttcc acactaattt cttcgttcaa tttcactaat aatacttgat
       61 ctcgcttatt ataatcgctt tcatttatcc taagagtcaa atctttttcc accataactt
      121 ttacacccaa taaattttgc ggtttatttt tctctgttga aattctttgt gtagccttta
      181 aactgacaat tagctcattg ggtacatact ctatttgaga gtcatctaat tggctcataa
      241 tcctttcttt ttggttagta tctgcagtta cttgtttagt atgagccatg aacccaaaca
      301 tactcacccc aacaaccaat cctaaatata ttttcttttt aaactttttc atctacatct
      361 cctcctaata gttttatttt agagttagct ctattactta tttactaact caacaacaga
      421 ttatcataca cttgttaatg aaatcacaat atctcattaa aacacaccct aaaatcataa
      481 ccgttcctat gctcattttt tggatttttt aatcacgtaa ccagaaaaat aaatcccctc
      541 tatttcacgc aaatcaaaga agaactaagt aactaccgtt taaaggtagt tacttagttc
      601 ttctttgatt attatctaac tttattattc attccccacc ctttgcgcag tgagtcttcg
      661 gtatcttgtt ttatctgact ggtagttctt attatttctc cacgatcatc taattctgga
      721 acaattggat atttttctct gaacaagtct agttctttca ccacgtcatt aaacaaatct
      781 tgcttatctt cttgcgtaag attctgttta atatactcat ctaaagcttt tctaagcaat
      841 tcatctcttg tcatattagt ctcatacttt tctactaaaa ctctggaagt cgcatttaac
      901 aaagtcgaca gttttaaagg atgcttggtg gaataaacct tatcaaactt tctgattggt
      961 gcgccaactt tttttgttct tcctctactc tgtctttcaa cattggagga agtttttatt
     1021 tcttgaactt ggtgcacttc taattgctta ttttcagatg gtgtaattgc ttgctgcttt
     1081 ttctttgctt ctgcttcttt ttttattttg gcgagtcctt tgttgttccc aaaaatatca
     1141 agtcctttga tgtcagccaa ttactccacc tccgcatacc aattctcgtg ttcttccaat
     1201 tctttcaaaa tactgataaa taattcgtgg cttttgcgat cccattgttt taagagacct
     1261 ttctttgtct tctccatcgt aatacctgat ccgtcgtatc gttttaagcg cgcatttttg
     1321 agtacaacat ttttaatcaa atgttcccca taaatctctt gggcttgttt atacatttcc
     1381 tgatctactg cgtcaccgct ttccaacatg aaaggaataa caccagcaac atataaattt
     1441 gtatcaaatt ctttcacaaa aaagtccata tactcaagat attgcatcgc atttctcatc
     1501 gattttactt gggtctgtaa gacgacgatt gcccaatccg caatgtacat cgcggattta
     1561 ctatatacag aaatagaagg tgggacatct aaatagatga cgtcaaactc atcaaataat
     1621 ggttctagct tttctttcat atatttgaat tgggataatg aatcattata ttggtctttg
     1681 atccaatcat catacatttc aaaggacatg tctgctggaa gtatatagag gttattgatt
     1741 actttataga cagcctcttt aggtggaaga ttgtttatca acacgtcagt cacagtattt
     1801 tcgtaaacaa tcggttcacc ttctccgcct ccttcttcgt tagtgaagtt catatgcgtt
     1861 aagttcatca catcagaagt atttccttgc atatccaagt caattatcaa ggttcttttt
     1921 ccttcattaa ctgctgattc aaaccctaac atttgcgcgc acgtactttt acctacgcca
     1981 cctttaaaat taccgattac atatttcttc gctaccacgt tcctacctct tttcttttag
     2041 caatattcat ttgatactat tataacatat ttatttttag ttactaccaa aaaaaagata
     2101 tatatgtact accttataat taataagtaa aaggtagtac ataaataagg aaaagctgaa
     2161 atatattgat ttatagcttt cctcaaagta atgacgttat ttaatttatc gagaagcaga
     2221 gaatactcgc gactttagtc atgtagatga atcagatctt cgataaaaaa gaagccgtcc
     2281 ttcttaagaa cgacaacaaa tcactagatt aattttttca actgttcata aaagttttca
     2341 tgcgttccac ataacaatac tggaataacc ttgttttcta taatctcgta agctactcta
     2401 tatgttgtgc ccgcatattt gaacccacta gaccaaatac ctgataaatc cccagttttt
     2461 tgttcaccct tatatggatc aatcgcaatt tcatcataaa ttaaattcaa aaatttttct
     2521 ttcaatggct tctcttttag cttttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgcata
//
LOCUS       DAIGQM010000126         3688 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.133, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000126 DAIGQM010000000
VERSION     DAIGQM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.133"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..716)
                     /locus_tag="NOA48_002670"
     CDS             complement(<1..716)
                     /locus_tag="NOA48_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0790888.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLY"
     gene            877..1566
                     /locus_tag="NOA48_002671"
     CDS             877..1566
                     /locus_tag="NOA48_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI0790889.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            1580..3082
                     /locus_tag="NOA48_002672"
     CDS             1580..3082
                     /locus_tag="NOA48_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0790890.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3095..3571
                     /locus_tag="NOA48_002673"
     CDS             3095..3571
                     /locus_tag="NOA48_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0790891.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKYGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1208 a          516 c          671 g         1293 t
ORIGIN      
        1 atataaagtt gtgatatttt tccagctaaa gatccaccat taagaaattc ttcaatggct
       61 gtttgtaaaa ctaagtctgc agactttcct ataggtgaat gaatatagtt agttatagca
      121 ataatttttg cgccattttt tttagctatt ttcaatgaat cataagtatc tttcgttttc
      181 ccagataaag aaaaaatgat tactaaatca ttaactgtta ataaagaagc gacttgggct
      241 tgaaaatgag ggtctagtac agcttttgct tgaactccta cgcgaagaaa catattttct
      301 aaatcaagac tagtatttcc actagatccc actccaaata tatatatgtt ttttgattga
      361 gtgatcattt taatggcttc attcaatttt tcttcgtcta aaagcctaat agtggaatag
      421 agagcttctg ttaaactatt agcaatttca tcatagtact ttacactagt cggatgttct
      481 tttttttgac taaagtcttc ctttgcaatt tcaattttta aatcagaaaa accagaaaaa
      541 ccaatttttt gacaaaagcg aataatagta gcatcgccaa cttttgtgtt tttcttaata
      601 tcactcatcg tactataaat aatagttttc ccagaattta aaataaaatc agcgactttt
      661 ttttcagact tcgttaaaaa tggataattt tctttaatta aatagatata actcatacaa
      721 actcctctac aatttcaact tttctccatt atactccaaa ataataaaaa aaactcctaa
      781 atactccatt tttatcttta cttttatgaa agcggatgct atattgtttt tggagttgtt
      841 atccaaaaat aataaaaaat tggagtgttt aggataatgg ataaaaagag gtttttagat
      901 cttatttcaa aaggtttgat tgtttcctgt caagcattac ctggtgaacc attttacaaa
      961 gaggaagaaa gtttaatgcc ttattttgct ttggctgctc aaagggctgg agcagttggt
     1021 atacgtgcaa attctgttcg agatattatt gaaattagaa agtgtgtatc attaccaatg
     1081 attggaatta ttaaaagaga ttatccacca gaatctccat tcattactgc cactatgaga
     1141 gaagtagatg aattagtaga aaccggtgtt gaggtaatcg ctcttgattg cactcttaga
     1201 aatcgacatg atggactatc tataaattct tttattacta aaataaaaga aaaatatcct
     1261 catcagttat ttatggcaga tatttctaca tttgaagaag gcaaaaatgc atataaagca
     1321 ggaatagatt ttgtaggaac tactttaagt ggatatactg aggaaagtaa aaaacaagat
     1381 gggccagata tagatttgat taaaaaattg gtagaagaag ggatttgtgt aattgctgag
     1441 ggaaggattc atactccaga acaagcaaaa gagataaaaa aaataggagt tgcaggtatt
     1501 gttgtgggtg gtgctattac tcgaccacag gaaattgcat caagatttgt taaagcatta
     1561 agttaggggg agaaataaaa tgtttaaaaa attttcacaa ttaggacgcg ctttcatgtt
     1621 accaattgct atattaccag tagccggatt actattggga ctgggaggag cgttaacaaa
     1681 tgagagtgct ataaatgctt atccattttt agatcaaccg tggttgcata caattttaag
     1741 tattatgagt tatgctggaa atgcagtttt tgcaaaccta gcactaattt ttgcaattgg
     1801 tattgctgta ggacttgcaa atggagataa aggaacagct ggtttagctg gtggagtagc
     1861 ttatttagta tatactgcaa ctattagtgg gtttcttgaa cttttttcag caaaagatgc
     1921 aacactagat acaggtgtag tgggatcaat tgttgttggt ggtactgttg catttttaca
     1981 caatcgttat agaaaaattg aattaccaca attcttaggt ttttttggag gatcaagatt
     2041 tattccgatt gtttctagtt tagctgcaat cattattggt tctttctttt atttaatttg
     2101 gccaccaatt caaaatggtt tagtagttgc tggtgaacaa attgcccaaa tgggtagttt
     2161 aggaactttt ttatatggtt ttttattacg tttaacaggt gctgttggac tacaccacac
     2221 catttaccct ttgttctggt atacatcttt aggtggtacc gaaactgtag ctggatcaac
     2281 aattgctgga gcccaaaata ttttctttgc ccaactagct gatccaaacc acactggtct
     2341 gtttacttat ggtactagat tttttgcagg aagatttgca acaatgatgt ttgggttacc
     2401 agcagcatgt tatgcaatgt atcgtgcaat tcctaagaaa aatcgtaaaa agaatggtgg
     2461 gctttatttt agcggggccc ttacatcatt tttaactgga attactgaac cagttgaata
     2521 tatgttttta tttgttgctc cttggcttta tgtgattcat gcattcttag atggattatc
     2581 tttttatttt gctgatatct taaatattcg tgtagggaat tccttttcag gtggtttgat
     2641 cgacttttta ttattcggtg tacttcaagg gaatgacaaa actaattggt taaaattaat
     2701 tccttttggt attgcatggg catttatata tttctttgtt tttacattct ttatcaaaaa
     2761 atttaaggta gctattcctg gaatggaaga agaatcagaa gttcattctg aaaaagtaat
     2821 aaacaaaaat acatcattac atgaagagtc tcttatcatt attgaagctc ttggtggaaa
     2881 agaaaatatt gagtctgttg aagcttgtgc aactcgtttg cgtgttgctg ttacaaatgg
     2941 ggagattatt caaaaacaaa caataaaaga cactggtgca actgctgtct tcgaagtgaa
     3001 gggtggcatc caagctgttt ttggagggaa agctgactta ttaagtcaag aaatcaatca
     3061 aatattagga aaagataatt aggaggtttt taatatgttt gaaattttca aaaagaaaaa
     3121 acaagaaact ttttatgcac cttgttccgg aaaaatcatt tccatcacag aagtaaatga
     3181 tcctgtcttt tcacaaaaat tactaggtga tggttttgcc gtcatacctg atggttcaaa
     3241 aatttatgct ccattggctg gtcgagtaac aaatatattt cctactaaac atgctattaa
     3301 tataaaaagc aactcaggca ttgattattt gattcatatt ggaattgata cagttgaatt
     3361 acaaggagag cctttttcga tttgtgttca agaaaatgat gaggttactc ctgaaacctc
     3421 gttggttgat gtggattttg acaaaataat aaaatatggt aaagatactt ctgttatagt
     3481 tgtttttccg gagaaaaatc agttcaatga tttaataata gataatggtc gaattgctca
     3541 tgggaattca tgtggaaaaa tcacttttta aaaaagtgta tataaaaagc tataaaataa
     3601 gctaaatagg atatttgtca aatgaagttg gtgaacagaa agaactgttt tctttctgtt
     3661 cattttttta ttttattagt aatgattc
//
LOCUS       DAIGQM010000127         3666 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.134, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000127 DAIGQM010000000
VERSION     DAIGQM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.134"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(130..429)
                     /locus_tag="NOA48_002674"
                     /pseudo
     CDS             complement(130..429)
                     /locus_tag="NOA48_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
     gene            617..1786
                     /locus_tag="NOA48_002675"
     CDS             617..1786
                     /locus_tag="NOA48_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790892.1"
                     /translation="MNDFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2091..2783
                     /locus_tag="NOA48_002676"
     CDS             2091..2783
                     /locus_tag="NOA48_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0790893.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKIHNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            3211..3603
                     /locus_tag="NOA48_002677"
     CDS             3211..3603
                     /locus_tag="NOA48_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790894.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
BASE COUNT         1430 a          470 c          569 g         1197 t
ORIGIN      
        1 taaaatcttg atttaactag tttttttctc tcgtcttttt tatagatatg tataccttcg
       61 aaaagacaag aaataaaata gaaatacctg tttagtgcaa aatgagaaga atctttttta
      121 attcatagtt tataatttat ggatttctga tttagtcgta ggtgcatttt taatggtatc
      181 agctaccgga caagtacgat caataaatgc gataaaatct gaaatctctt catcagtatt
      241 atcagcttca atataaaatt tagatacgat tgcagaatag cctattttag ctgctttatt
      301 ttttcctata aaaccatcag gatctaatac tccatctatc tctacacgga tatcgtttaa
      361 atttatgccc tgcactttag cgaaagaccg agctacaata actttacatg ctccaagaga
      421 ggctaataat aagtattgga gatggtgcga agtaagattg ataaaaaatg gataaaggat
      481 tagatttaat acaatgtctt atcacgattc taatgatttg atgagagtgt aaaatatttt
      541 gtgtaaatag aaaaaaggaa gtcccttctg tagaatagag ttaccacaac acattcacag
      601 aaaagaggac ttccatatga acgattttac tacagaaatt atggaaacac taatcaataa
      661 aggtgattta gatgaattat ttcgatgtca tttagaatta gctgttaatt cattattgca
      721 ggctgaatta acagcttttc ttgattatga aaaatatgat cgtgctgggt tcaattcagg
      781 taattcccgt aatgggaatt attcacgttc attcagaaca gagtatggag aattaaattt
      841 ggtgattcct agagatagaa atggtaagtt ttctcaacaa actttacctg cttataaaag
      901 aaccaatgac tctttagaaa ccactattat tcagctattt caaaaaggaa ttactatgtc
      961 tgaaatctct gaattgattg aaaaaatgta cgggcatcac tatacgccac aaaccatttc
     1021 aaatatgact aaaatagttt ctgaagatat tattgccttt aaagaaaggt ccttagaatc
     1081 cagatactct gttattttta tggatgctac tcacattcct ttaaaaagac aaactgtttc
     1141 aaaagaagca gtttatattg taattggcat tcgattagat ggaaccaaag aggttcttgg
     1201 gtttagtctt gctccaactg aatctgctta tgtttggaaa gagattcttc aagacctaaa
     1261 agaccgtggt ttaaaagagg ttttattagt cgtaactgat ggtttaagtg gcattaacga
     1321 tagtattcat agtgtttatc caaatgctca atttcaacaa tgttgtgtcc atatatctag
     1381 aaatatcgct cataaggttc gtgttagtga tcgacaagaa atctgtagcg atttcaaatt
     1441 agtttatcaa gcaagttcaa aagaagaagc aaataatcaa ataaggttta tgatagataa
     1501 atggaaaaag cagtatccac gagtggttaa attgctcatg aatcctgcta tattaacctt
     1561 ttataatttc cctccgtcaa tcagaagaac tatttattca actaatttga ttgaaggttt
     1621 taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa tttcctaatg aagaatctct
     1681 ggagagattt ctagtatctc aattcaacaa ctataatcaa aagtttctat gccgagttca
     1741 taaaggtttt aaagaaatac atgatacatt agaatcaatg ttttaacttg atcaacagaa
     1801 tgggcttttc catttacaca taattcttga cgcaacctat tctggaaact tacaaataaa
     1861 agcttattct tcagccacct tcgggtggtt attttttata aaaaaatgta aaaaaatatt
     1921 gatacataaa taaattagtt gtagtaaata gttttagaat tgaatttctc tatccttttt
     1981 aaataatttt ttagacaaaa aacagaaagt gtctaaagaa agcttgacga agaaaataat
     2041 ttttaataac ttatttaagg taagaaaatt ttttgaagga gaagataaaa gtgagaaaaa
     2101 agattattat taatgctgga gtaattatag gattgatgtt agtaattttc tccggaaagc
     2161 aatatgctga taatatttta ttatggggag gggaagataa tattgaaaag atccacaaca
     2221 atttaactat attagacaca gctctagaaa ataaagagca aaaaattagt attttaaatt
     2281 cacaattgtc ttcaaacaac caaactcttg aacaactaag aactaatatt gaagtttcca
     2341 aacaaaaagt ggcatcttta gaaaacgaca agaatcaatt agtatcagag aaaactaatt
     2401 tagaaaatca attgtcagca aaagactctg aattgcaagg aaaacaaaat gaaattaatg
     2461 cgaaaataga cgaaattaac caaaaagtag ctgaaataaa tcgattaaat agcgattgga
     2521 ataatcgttt acaaaatgaa aagaacaaat ttaatgaaga acaatctact attaatagtt
     2581 taaaccagca aattaatcaa atgttgagtg aaaaaaataa cattcaaaat caactgcaag
     2641 ctactcagca aaagctagaa gaagaaaagt caaaaaatag tagtttgaat aattacattg
     2701 aaaagcttca aaaagctaaa aatgatgtag aggataccgc aaataaagca caacaaattg
     2761 taaatgaaca tacaatccaa tagatatagt tttaatttaa caaatggtat gtttggagat
     2821 aatgagatag aatataaatg tcataatatt atacaatcta aacaccgttt ccttttctat
     2881 ttttgatgac atcagtatat agctactcga aagagtagtc tttttattat tctcgcttat
     2941 tattgatatg aaaatttcga tttgacaaaa ggtaccgaat aattttgtaa tatgaattat
     3001 tatcaagaag taattatgat gataacatat ggaaactagt tagtaataat cacaggtgat
     3061 taaacttttg aacgacttgt aattctatat tttttctttt aagtaaaaaa tataggtgag
     3121 tttttttgac ttcatattta taataaagac acgtaaatca attatttttc attttacttt
     3181 aactaataat gtttatttgg agggattatt atgttagatg atagattgac gtgttctaat
     3241 tgtggtacat tattttacta tgaggaagtt agaaatattg taaaacatag aaaaaaagaa
     3301 atgcctatac gttgtccaaa ttgcaatgaa gttattaagc gaaagttgtc tcatggttat
     3361 tttgtcagct acgaactata tgaagaaagt aaaataaatc tgaaaaaaaa accaaaatac
     3421 tataaaaatt tgaaaactgg agctattata actgaaaaag aatttaaaaa tttagtgact
     3481 gaagaagaaa gcaggtttta taatttgtct ggtaatattt gccctggatt tatggatcag
     3541 attattgaaa atgagtcaat tgaatcaatt gaaaactatg ttcctgttga cttaccaaaa
     3601 tagaaaaaat aatcctgttt ttacagtgaa ttattttaat tttgattttc aataaaaata
     3661 tattac
//
LOCUS       DAIGQM010000128         3419 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.136, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000128 DAIGQM010000000
VERSION     DAIGQM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.136"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            164..715
                     /locus_tag="NOA48_002678"
     CDS             164..715
                     /locus_tag="NOA48_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HCI0790895.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1391..1645
                     /locus_tag="NOA48_002679"
                     /pseudo
     CDS             1391..1645
                     /locus_tag="NOA48_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1715..2227
                     /locus_tag="NOA48_002680"
     CDS             1715..2227
                     /locus_tag="NOA48_002680"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790896.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2224..3261
                     /locus_tag="NOA48_002681"
     CDS             2224..3261
                     /locus_tag="NOA48_002681"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0790897.1"
                     /translation="MISFSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1253 a          576 c          678 g          912 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgaagagc gagcaagaca ggaacgagag aacaaacata ctcatgaaaa gactagaggc
      181 ttcgacctcg aactttaata ataagttaga tgtttttgaa gaaaagacta agcatgcaag
      241 attaaacttt gaaacaactg caaagcacta tattaaacga cttgatgaag ataatttgaa
      301 attagatttt caacaagcta ttcaagatga attaagcgat actaaagacg aaatacgtga
      361 agtgacgaaa caagcgagag aagaaacaaa agagtataaa gaaatcttag aaagtaaaat
      421 aaaagaccat aacaaagtgg ttgataaatc gaatacagcg ctaaaagtga tgacaaaagg
      481 cgttacaaat atattttttg tgctaattat ttttgtactt gtaatgcttg tgacaggtcc
      541 gataggtcat ttctttggta ttgaacattt atatagcttt attaatggtt ttattgatga
      601 ccacgaaagt gcatggcgat atttgatgtt gatactttat gcagtaccct atgtattctt
      661 cgctatcatt ctgtggctca tagcattgtt ttttagagta tttaatgacc tttaggtaga
      721 tttatatata aaaagggcta aatacgcaaa ataccccctt aaaatgcaaa ataaatgcaa
      781 ataagggggt aactccttat gaaaaaacaa ctaatagtat tataacacgt ttttatgccg
      841 agaaaactta ttggttggaa tgggctatgt gttagctaac ttgttagcga gttggttgga
      901 cttgaattgg gattaatccc aagaaagtac caactcaaca acacataaag ccctgtaggt
      961 tccgaccaat aaggaaattg gaataaagca acgaaaggag ttgagtaaaa tgagtgagaa
     1021 aacgaagaaa atcattcgag tatcattagc tttttcacaa gtagtagtgc aatcattgat
     1081 agtttattat acttaccagc aatataaatt atctaaagag aattaagttt tgattatgta
     1141 ataagttttg gtactaaaaa agacttgatc taattagacc aagtcttttg ttagtgttat
     1201 attaataaca aaataaaaat aagaagtcgc tcactccccg accaaagttt gtgagcaaaa
     1261 taaacagtcg atgtttgttt cttaattgta tatcttgata ttaaacgatt taagattatt
     1321 cttcaagata tatattcgca aatgtaattg gaaaagcgac ttcttaaaca aaattaagga
     1381 gtcgcttttt atggcaaaaa taacgaaaaa tgagcaagaa aatttggtgg aaaattacac
     1441 aaaaaaaccg gcgtactcta atagccggtt agacgcacat ttcgtgtgca cttctaatcc
     1501 gaaattgagc tttgacgcta tgacgatagt cggaaacctt aataaaaaca gcgctaaaaa
     1561 gctatccgat tttatgagtt tagatccaca aattagactt tgggatatac ttcaaacaaa
     1621 atttaaagct aaagcactac aagaccccct atgttaggct agttgtcgta taggataata
     1681 agttataata aagactatac ggaggatgat taccatgaca aataaaaaca atgaacgtta
     1741 ctctaccgaa ctgaaagcga cagccatcaa gaaaatgatg ccacccgaaa atagggggat
     1801 tcgccaatta agtcaaactt tgggcattcc agaagcgact ctttgttctt ggcgtaaaaa
     1861 agctagaatt caagggaata ctacacccgg aacgaaaaaa aatgtcgaaa aatggtcaag
     1921 tgaagataaa tttttaattg tgatggaatc attctcaatg aaccaagtag aacttgcgga
     1981 atattgccga aagaagggct tatttaaaga acaaattgag gcttggaaga aaacgtgctt
     2041 atctgcgaat gaacaggaag aaaatcgaac gagagaactt gcaactgaac taaaagaaga
     2101 gaaaaaacaa gcgcgtcaat tagagaaaga attacgtcat aaggaaaaag cattagcgga
     2161 agccgctgct ctcttattac taagaaaaaa agcacacgcg atttgggggg accaagagga
     2221 agaatgattt cattttcaga tcgcaaacaa gctgttgaac ttattcaaga agccaatcgc
     2281 aatggggccc gtctcaccta tgcctgtaat gagctgaata ttagcgttcg aacctacgaa
     2341 cgatggacgc gtgaaggtac gatagcgcat gatcaacgcc ctttggcgaa acgtcctgta
     2401 cccaaaaata aactgacgga tcaagaacgc gaaaaaataa tagaaaccgt ttcaaaaaaa
     2461 gaatttatga atttgccacc tagccaaatt gtaccaaaac ttgcggattg ctcgatttat
     2521 attgcatcag agtctagctt ctatcgtgta ttgcgagaaa aaaatatgca acatcaccgt
     2581 ggccgaagtc aagtttcaca aaaacgcata ccgccaagtc accttgcgac gaagccaaat
     2641 gaagtttgga cttgggatat tacttggcta aaaggtccaa taaaaggact cttttaccgg
     2701 ttatatctca tcattgattt atttagccgt aaaatggtag gctgggagat ttgggaatca
     2761 gaagaagctc gtcatgccga aaaacttatt aaacagacgg tgcttaagga acgtatccaa
     2821 ggacagccgt tggttttaca ctccgataat ggcagcccta tgaaagccgc gacttttcaa
     2881 gtcttactcg aaaaattagg aattcaaagt tcttattcaa gaccacgagt gagtaatgac
     2941 aatccttatt cggaagcggc tttccgaacg ttaaaatatc gaccagaata tcccaataac
     3001 ggctttaaaa caatagatga tgctcgaaaa tggacgaaag agtttgtcga ttggtataac
     3061 gattctcatt tgcatagtgg gattcaattt gtgtctcctg cagcgtgtca tgaaggacga
     3121 catctcgcta ttttagagaa acgaaagcag gtttacgagg acgctaaaaa gcgccatcct
     3181 gaacgctggt caaaaggtgt tcgaaattgg actccacatc aatcggtggc gttgaatcct
     3241 ttaaaagaaa cagaaagtta acaggagcat aatctttcaa gattatcaaa taaccctcgt
     3301 cacccaatag gggaaaaagt tattcttccc ctattggata acgaggccaa ccgaccatag
     3361 ggaggttctg ctttttgata ggtggaaaat aaaaatacga caactatatt gacaaacac
//
LOCUS       DAIGQM010000129         3234 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.137, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000129 DAIGQM010000000
VERSION     DAIGQM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.137"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            160..1899
                     /gene="yfcC"
                     /locus_tag="NOA48_002682"
     CDS             160..1899
                     /gene="yfcC"
                     /locus_tag="NOA48_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI0790898.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2056..>3234
                     /gene="iadA"
                     /locus_tag="NOA48_002683"
     CDS             2056..>3234
                     /gene="iadA"
                     /locus_tag="NOA48_002683"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCI0790899.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     S"
BASE COUNT         1006 a          540 c          755 g          933 t
ORIGIN      
        1 agaaaaaaat aatcatacat aggagaaaaa aaacaaaata gaaaaaagtg attttctaat
       61 aaattattca tgtggaaatg tcatttttac tgtataattc atttgattat ccatttttta
      121 ttcatcaaaa ttactgaaaa aagaaaggaa gaaataaatt tgaagaaaac aaattcttca
      181 ggaaaaccga aacgcgactt cactaaatta tcgacacccc atacgtatgt cattattttt
      241 ggtgtagtca tctttgcatg gatactgact tttgtcgttc cagcaggaaa gttcagcacg
      301 caagatattg aatacaaaga tgcaaatggc gaaacaagta ctcgtactgt tttacgtcaa
      361 gattccttcc gttatgctta cgagctggat aagtcgtatg tgtttgatca attagaagaa
      421 ctgcaagatc atccagcaga acgtgaaaaa ctggatgttc cggaaaaagg attggaaaaa
      481 gtcattgctg acggagaaaa aaatcttacg caggaaaaac tagatgaaat ctccttgaca
      541 gatgatgtgc tttacgatca gtacggcgaa aatatctatg atacttctaa aaaattgcat
      601 aaaacagcca aaatatgggg aacagatgat tttggcggct ttggtttctt aaattttgtt
      661 tttgaaggac tagtatctgg agataagtat ggatctgctg tagggatcgc tgcattgatc
      721 cttgttgttg gaggtgcttt tggtattatt atgcgtaccg gagcgatcga cgcaggtatc
      781 tatgcgttta tcagtaaaac taagggactg gagcgtttag ctttaccgct attattcttt
      841 gctttttcat tcggtggcgc tacattcggg atggcagaag aggtaattcc attctcaatg
      901 gtgatggttc catttgtcat tgcgttagga tatgactcga tcgtagcagt aaccgtgact
      961 tatgtcgcat ctcaagtcgg aaatgcgacc tcttggatga gcccgtttag cgtagcggtg
     1021 gctcaaggga ttgctggaat ccccgtgttg tctggtgcga cattccgatt gattatgtgg
     1081 gtagttgtta ctgcattagc cgctggttat atgatgatat atgcagaaaa aatccgtaaa
     1141 aaaccagaaa gttcgttgac ttacaaatca gatgattatt tccgttctca tatcaaaaag
     1201 acatctgatg aaaataaaaa attcatgctt gggcataaat tgatcttatt agagatgtta
     1261 gttgtccttg tctggatcgt ttggggcgtg actcaaaaag gctattacat tccagaaatc
     1321 gcttctcaat tctttgtgat gggattagtt gctggaatca ttgctgttct tttcaaatta
     1381 gatggaatga aagtcaatga catcgcttct tctttccaat ctggtgcagc tgatttagct
     1441 ggtacagcaa tcgtagtagg tatggccaaa gggattcttc ttgtcttggg aggatctgat
     1501 gcatctgttc cttcagcttt gaatacgatt ttgcatggga tcgggacggc gttgaccggt
     1561 gttccagctg tcattggtgc ttgggcgatg tacatcttcc aaagtttgtt caacttggtt
     1621 gttacatcaa attcaggaca agcagctttg actatgccaa tcatggctcc actggcagat
     1681 ttagtaggtg tatccagaca agtagcagtt cttgcttatc agcttggttc aggttttatg
     1741 gacgctttta cacccgtatc agccagcttg attggtgtgc taggtgttgc acggatcgaa
     1801 tgggcaaaat gggcaagatt ccaaatcaag atgcaaggat tcctgtttgt tttaggaact
     1861 attttcatca tgattgccat tgcaataggt ctgcagtagt actggagacc tgtaaataaa
     1921 aaagtaatcc aaacagtaga taaggactcc aagaaccgtc attttacggt aaaatcaaag
     1981 gagtaaagat cctatcgttt ggattatttt ttaagatcct atcatcagtt atacttaaag
     2041 aaagaggaaa aatgtatgaa aatcattcga caaattgaag tgtttgcacc agattactta
     2101 ggaaaaatgg atgtactgat tgccggtggg aagattttgg ctgtagaaga acagctagaa
     2161 ggcggctacg aaggagtgga agtagaagaa ctttcaggtg agggaaaagt actaaccccg
     2221 ggtttcattg actgtcattt ccatatttta ggtggaggag gagaaggcgg ttatcaaaat
     2281 cgaacgccag aagtcacatt gagccaattg actacagctg gtgtaacgac agttgtcggt
     2341 tgtttgggaa cagacggaga aggtagagat atgactgcgt tgatcagcaa agcgaaaggt
     2401 ctggaagcag aaggaatctc cacttatgta tacgaaggtt cgtaccgatt gccggtaaaa
     2461 acagtaacag attctatcat caaagacttt ttgacaattg ataaaattat cggaatcgga
     2521 gaaatcgcag tatccgatca ccgttcttct cagccaagtt ttgaagagtt cgctcgtgca
     2581 gtagcagatg ctcgtgtagg aggcatgtta tccggaaaag ctgggatcat caatgtccac
     2641 ttaggcggag gaaaaagaaa gctagagcta ttgacacgaa tcgtagaaga aacagaaatt
     2701 ccgatcacac aatttttgcc tactcatgca aatcgcacac cagaattatt tgaagcttgc
     2761 gtggcatttg ccaaacgtgg tggcacgatt gacttcactg ctagcgaaga tcctgatttt
     2821 tgggagaaga cagatggtga agttcgcttc agcaaagcac tgaaacgatt gatcgaggaa
     2881 gatgtttctt tagataattt cacgatgacc tcagatggac aaggaagctt gccttatttt
     2941 gatgaaaaca atcatttcct agggttagga gtaggaagtg ccaaggcatt gctagtaggg
     3001 atcaaagaag ctgtgcaaaa agaaagtatc cctttggaaa tcgccttacg agctataacc
     3061 agtaatccag cacgtatatt gaaattggat aaaaaaggaa aaatcgaaat tggtgctgat
     3121 gcagatctgt gtatcttgga taaagaaacg cttgatattg atacagttat cgctaaagga
     3181 gaaataatgg tccaagaaaa agaagtcaaa gtatggggga ctttcgaaaa aagt
//
LOCUS       DAIGQM010000130         3189 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.138, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000130 DAIGQM010000000
VERSION     DAIGQM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.138"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            2..586
                     /locus_tag="NOA48_002684"
     CDS             2..586
                     /locus_tag="NOA48_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0790900.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1856)
                     /locus_tag="NOA48_002685"
     CDS             complement(663..1856)
                     /locus_tag="NOA48_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0790901.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1920..2300
                     /locus_tag="NOA48_002686"
     CDS             1920..2300
                     /locus_tag="NOA48_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCI0790902.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="NOA48_002687"
     CDS             2374..2736
                     /locus_tag="NOA48_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790903.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1076 a          521 c          606 g          986 t
ORIGIN      
        1 tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg ttatcaaaac
       61 aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga cggttcaaaa
      121 tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc gcgttattcc
      181 tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg aaagtattta
      241 tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg gagctttatc
      301 tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa ataacacaaa
      361 tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag aaatcattga
      421 agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct ttggacatgt
      481 actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc cacaagaccg
      541 acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg gtatggtacg
      601 gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt tgaataaatg
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcg
//
LOCUS       DAIGQM010000131         2944 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.139, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000131 DAIGQM010000000
VERSION     DAIGQM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.139"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            133..750
                     /locus_tag="NOA48_002688"
                     /pseudo
     CDS             133..750
                     /locus_tag="NOA48_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            924..1133
                     /locus_tag="NOA48_002689"
     CDS             924..1133
                     /locus_tag="NOA48_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790904.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            1340..1540
                     /locus_tag="NOA48_002690"
                     /pseudo
     CDS             1340..1540
                     /locus_tag="NOA48_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1640..2941)
                     /locus_tag="NOA48_002691"
     CDS             complement(1640..2941)
                     /locus_tag="NOA48_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0790905.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
BASE COUNT         1043 a          462 c          587 g          852 t
ORIGIN      
        1 tatcatgaaa aattagttgc ttttgtcact tagcgctgaa aatttatgcc atttatctag
       61 aaaaatgaca acagagttgg gcaacagaat ttaaaaatga tccggatttc agaattttaa
      121 aggagtttta ttatggcgaa aattgggtat gctcgagtaa gcagcttaga ttaaaattta
      181 gaccgacaat tagaattatt atcagagtgt gataaaattt ttagtgataa agcaagtggg
      241 aaagatacca atcgagaagg atttcaagaa atgatgaaat tcatacgtga aggtgatatt
      301 gtcgttgtga cagaattaaa acgacttgaa cgaaataaca aagagctaac agaaacgatg
      361 aatttaattc agctgaagaa agctacactg gaagttttga atttgccagc gttaacaggt
      421 atcactgatg ataatttacg tcgattactt aataacttaa ttatcgaact atacaagtac
      481 caggccgaag aagaacgtcg gtatattcgc gaaacgcaac aacaaggaat tgcactcgct
      541 aaagcaaaag ggaaatacaa gggaggtacg ccaaaatatc gtgagaatga tccgcgactt
      601 caattagcat ttaatttgtt tttgactaga tctacagata aagaagttga agagctaaca
      661 gggattaatc gtagaacgtt tagaagatat cgaatgaaac atggtattac taatgaagtt
      721 agggagcaaa aaaataaatc tttcagttga ggctaatata attttgcaag aaagggattt
      781 ttatgaaaga aattagattt tcaaatcaaa atatgcagaa ttactataat gaaattatga
      841 atatggaaac tagtgaattg aatttaatta tagccgaaaa aaaagttgca ttggatagga
      901 ataaaaactt attaaatgta gttatgatct gttatatttc atttctaata ctaggtcttc
      961 cacaagcagt gtttcctgaa atgttttctg gagactgggg tattgtcagc tattctatat
     1021 taacattgat tgctatggtt ttaggtactt cattttataa tgcttttgta agtaagcatg
     1081 ttgaggaata tgaagtatta atgtacttaa aagagaaaaa aacaagtaat taatatgaga
     1141 acaccacgca tagtttttat tttgagatat cctagaatga aacacattaa gaacgaaagc
     1201 aaagcaaaag acggcagaac ttctactacc ttctaagttt tttcatattt gtttgttatg
     1261 ctatacatag atctgcataa ttagacttgc gctgcccgtt attgaagttt caggcagcgc
     1321 tctttttggg ggatcgataa tggaagaaga aaaaatattt gagaaacgct ggcagctagc
     1381 atcaagtgaa caaagagcaa gatacaataa tttgatcacc tcctacccca ctgttgacta
     1441 gacatataag gaaaagaaat acttactttg gctgtgccag ttagatatag atacctttga
     1501 aacatttgaa gtgatcctag ataaaattaa acagaattga tcagaaacaa gcgaagcctt
     1561 ctctcggttc gcttgttttg ctatttatta gttggctcag ggcaattcta agctcgtttg
     1621 aaagaaaacc gaatgacgac tatagttttt catctactaa ttttgtttta ttgctctcca
     1681 tgactttaaa aaatggatag tagatgaaga tgctgatgac gatcaacagt aggcaaaaga
     1741 gaatattgcg ccagtccata cttgaaagat aagcttgtgc aaaaaaaggt gtgaaggaag
     1801 gatcgacgat aaatccaatc ccaatccatc ctagttgctg agcaaagtag gtcagcaata
     1861 atgaaatgat gggcgtaatc aaaaatggaa ttgccaaaat agggttaaaa acgataggta
     1921 atccgaaaat cactggttcg ttgatggaac agattccagg aaccaatgac aattttccaa
     1981 ttgtgcgata ttcgggtact ttgcttcgca tcatcaataa aaccaaaccc aaagtaccac
     2041 cggctccacc aagtacagaa atacggaaca tttgtaagtt cattaagtgt gtcatggttt
     2101 caccatttgc cagttgttca gcattcaaac cagtttgagc cattcccaat gtaaagacga
     2161 tagggaaaat aattgacgag ccattgatac caaatagcca taggatgtta cccaaagtca
     2221 cgatcaataa gaaaccacct agactgccag cgatgttcgt tgctggagtc aggacttcca
     2281 tcaccgcttc agggaagatt ttgtttgttg ctgccaagaa aatcagattg atgccataaa
     2341 agatgaatat atttgtcagc agtggaacga gcatattgat aaaggttgct accatgggtg
     2401 gaactgtatc tgggagtttc aacttaatat tttttacttc aaatagtcgg ttgatttcca
     2461 ctactagcaa gccgatgata attgcgacga acaatccgtt tgtcccaagg aaattaagat
     2521 tgatggcacc ttcttccact ggtgtacaaa ccattagata aatgacagat gcaaccatgc
     2581 cattcatgga aggattaatt ttgtattcat tggcaaggga aaatgcaatg ccaaaaacac
     2641 taatgaatcc gatgattccc attgtcaaat tataaggggc tgtgatgaga tcataatttg
     2701 ctacggcaaa atctttccag ctggccataa atttcatgaa aatattagct gtatctggat
     2761 tgtatttatc aatattgatg ggtggatttg caaaaatcag aaaaaaagaa ccgataacaa
     2821 taaagggtag gccaaacatc ataccgctgg atatagcttt taggtggcgc tgattaccta
     2881 tcttggctgc gatggggcta agtatgtcat tcagtttcat gataaacgca gaattttcca
     2941 tata
//
LOCUS       DAIGQM010000132         2910 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.140, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000132 DAIGQM010000000
VERSION     DAIGQM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.140"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..332)
                     /locus_tag="NOA48_002692"
     CDS             complement(<1..332)
                     /locus_tag="NOA48_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HCI0790906.1"
                     /translation="MNKNITKARHFGFLLYPESIPENWREQLESLGVSMAVSPLHDMD
                     EKTNKKDWTSSDVIRNGKHYVKPHYHVLYIARNPVTIESVRKKIKRKLGNNSVAHLEI
                     IDHIKGSY"
     gene            complement(1049..1228)
                     /locus_tag="NOA48_002693"
     CDS             complement(1049..1228)
                     /locus_tag="NOA48_002693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790907.1"
                     /translation="MEKDIYKQLTRQIQKEKEKGLLDHLDELELKADEINKNRMSAKE
                     KGIKLKDSSLQSDKS"
     gene            complement(1353..1598)
                     /locus_tag="NOA48_002694"
     CDS             complement(1353..1598)
                     /locus_tag="NOA48_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790908.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLKYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1943..2227
                     /locus_tag="NOA48_002695"
     CDS             1943..2227
                     /locus_tag="NOA48_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790909.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            2230..2646
                     /locus_tag="NOA48_002696"
     CDS             2230..2646
                     /locus_tag="NOA48_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790910.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNQPKNHQKGTNKTVTSSNFDPTKFLKR"
BASE COUNT          882 a          584 c          433 g         1011 t
ORIGIN      
        1 tcatacgagc ctttgatatg gtcaattatt tctaagtgag caaccgaatt atttcccaat
       61 tttctcttga ttttctttct tacgctctcg attgttacag gattgcgagc aatataaagg
      121 acatgataat gtggctttac ataatgctta ccgtttctga taacatcact actagtccaa
      181 tcctttttat ttgttttttc gtccatatcg tgtaacggac taaccgccat tgatactcct
      241 aagctctcaa gctgttctct ccaattctct ggaatagatt cgggatatag taaaaaacca
      301 aaatgtctag ctttcgttat attcttattc atgatatact tacctcaatt gaacactatc
      361 agttaagcgg aaacggtgcg ccaacacata tgtttctgct ctttttttgc gctcaatttc
      421 ctttctctga ttttttcaag tcttctgtta ctagcaattt aacatatgtc gacatactca
      481 aacttttgtc ttttgctttt tcctcaagtt ttcgcttaat ttcactcggt aaaattacta
      541 ccagtctttc tgattccgcc atgcctttca gcccctttag ttaattgtta atatcatggt
      601 aaacttttga caactgtatt gtcaatattt ttttctattt ttcaaaacgg cggtcaaaac
      661 ggcggtcaaa tggcggtcga aaaaaaaagg ctctatccat tggtacagta aggataaagc
      721 actttttggc acaaaaattg gcactcggca cactatgggg gggtcgtagt agccccccca
      781 gattttccaa attccaaatt ttttccaaaa attttccagc gctatcgctc ggcaaatcaa
      841 gaccgtacct ttttgaaaaa aggcacccca aaaactttcc actcgccgtt aaggcgtcaa
      901 gaacgttccc tatggtcacc ttcttgtgtt tccagctttt gggttttgtt tatagccgtc
      961 aactccttaa agcctcaaag agacgctaag agggcttatt agcctctcta agcgtctcta
     1021 attcgattta ccgttgaccg cacgttatct agcttttatc gctttgcaac gacgaatctt
     1081 taagttttat acctttttct tttgctgaca ttctgttttt attgatttca tcagctttta
     1141 gttctaattc atctaaatga tctagtaagc ctttttcttt ttccttttga atttgtcggg
     1201 tcaattgttt ataaatatct ttttccatcc cccatcgcct ccttaaaagc tattattatt
     1261 cgatttaaga cgttttattt agtttttggt gttatttcat tggtccaagc taaaaaactc
     1321 ttagaagcga ttttagagcc atttaaaccc acttaattat attctccatg aaattcgctc
     1381 catgcgtcaa aagctgcgtc tgaaattccg ccgtcttcgt tcactagttg cattaatttt
     1441 tccaacgatc gttttctttc gggcgtcata tttttatatt tcaacaattt ttcgtctgtt
     1501 aaatcgaact tgattgcttg aattgcttgc tctaattttt ctaagttttg aaaatattcg
     1561 taaggaaatt tttccatttt ttctttctcc agtctcacaa tttttctaga aataaaatca
     1621 cttctttgcc gtctatactc tcaaaaaaaa tgtcgtttga aaaactaaat aaatttttga
     1681 tcgtgcattt ttaaatttgg ttatcgatca cacgtgcagc actccccccc gaattttaaa
     1741 gagcataagg aaacgtggta tcactttctt acgaaaggtg ctagataggc tgtgcctatc
     1801 acgtttcttt gaaaaaaatt tgatatcact ttttcgccat cgtggatagc ttatgtatag
     1861 tattttggca aaaaacagct atacaaatat agtatttgta tggtatacat aaattataca
     1921 taattgcaaa aggagatttt ttatggacat tttagttcgg aatattgatc caaagtttgt
     1981 tgcaacaata gacaaacgtt gccaagaact cacgaataaa acaggagaaa aatggagtcg
     2041 aaataaatat ctaaaagttt taatcgaaag tgattttgac cgtcaactta cgacttacaa
     2101 aaaagaccaa ttcgatttat tgctcgataa atttattgct atccaaacag aaaatactca
     2161 aatattaagc gagtatgtct acacaaataa tcaaatcatt gaaatgctta tcggaggaat
     2221 gatataacca tgagaaaaac ttctgtccaa aaacatgtta ctttgtaccc tagtcatgtt
     2281 gacgttttag attccatcat cgaaaaaaat ccagatatca ataactactc ggaagccatt
     2341 cgctttttat gtatgagtta tgaacccgat accaacacga ccactaccag caatcaggca
     2401 aaactaaatg ctatgggaaa agaaatttcc atcatgactg aaatcatcgc agaattcgct
     2461 gatttatatc taaaagatac aggcgttctt atcggcacaa attctaaagt atatcaagaa
     2521 gtgaaagaaa aaatcgaagc taaactaaat ccatcaaatc gaaatcaacc aaagaatcat
     2581 caaaaaggaa caaacaaaac agtcacttct agcaatttcg acccaactaa atttctaaaa
     2641 cgataaaaaa cagataggag ttattcctat ctgtttttta tttcccaata ttctattttt
     2701 tcattccaag cagttaacgg aagttttcga tatttattcg acgtgtttat tcacgccttc
     2761 aatcatttct ccagtttcag aatctatcct ttttgcatat tgcggccgaa atccgttctg
     2821 gtaattagca tcaaacatca tacggaaaag attgctgttt gaagctatga catcaacaac
     2881 atctctttga ttagtgattc catactcttg
//
LOCUS       DAIGQM010000133         2864 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.141, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000133 DAIGQM010000000
VERSION     DAIGQM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.141"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            95..1054
                     /locus_tag="NOA48_002697"
     CDS             95..1054
                     /locus_tag="NOA48_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HCI0790911.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="NOA48_002698"
     CDS             complement(1487..2059)
                     /locus_tag="NOA48_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0790912.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /locus_tag="NOA48_002699"
     CDS             complement(2075..2680)
                     /locus_tag="NOA48_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HCI0790913.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          918 a          581 c          471 g          894 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt
     2821 aaaagaagac aaaatagagt acagaaaatg ttttctgtac tcta
//
LOCUS       DAIGQM010000134         2634 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.142, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000134 DAIGQM010000000
VERSION     DAIGQM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.142"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..470)
                     /locus_tag="NOA48_002700"
     CDS             complement(<1..470)
                     /locus_tag="NOA48_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0790914.1"
                     /translation="MENENRTDWTLPRKNLNPKTKQPYKRGRNWWIVVYPESLPENWK
                     EIISTEPVAISPLHDKDVNADGTKKKPHYHIVFNYKGNKSFEQMDEMARVLRAPIPER
                     ISGLTGAVRYLTHMDNPEKYQYDNTEIQVFGGFDLESCLALSTGDKRQALKEMLG"
     gene            complement(594..749)
                     /locus_tag="NOA48_002701"
     CDS             complement(594..749)
                     /locus_tag="NOA48_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein repA"
                     /protein_id="HCI0790915.1"
                     /translation="MVEVEKKKVTLSLPVESNDKLEKMAQKYGMTKSGLVTFLINQAD
                     DKGTIFK"
     gene            complement(1293..2504)
                     /locus_tag="NOA48_002702"
     CDS             complement(1293..2504)
                     /locus_tag="NOA48_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003672456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI0790916.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNY
                     DLVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFF
                     DTAKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQ
                     DELPKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSND
                     KAPTIKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVI
                     KSYEELYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEK
                     ENKSLKNEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNE
                     TKTRDRDELSR"
BASE COUNT          727 a          567 c          365 g          975 t
ORIGIN      
        1 ccaagcattt cttttaacgc ttgtctttta tcaccagtag ataacgctaa acaactttca
       61 aggtcgaatc caccaaacac ttgtatttct gtattatcgt attgatactt ttcaggatta
      121 tccatatgcg ttaaatatct aacagcacca gttaaaccac ttattctttc aggaatcggt
      181 gcccttaaaa ctcttgccat ttcgtccatt tgttcaaatg atttattgcc cttgtaatta
      241 aaaactatat gataatgcgg ctttttcttt gttccgtctg cattaacatc tttatcatgt
      301 aatggactaa ttgccacagg ttcagttgaa ataatctctt tccaattctc tggcaaactt
      361 tcaggataaa caacaatcca ccagttacga cctcgcttat aaggctgttt agtttttgga
      421 tttaaattct ttctaggcaa tgtccaatct gttctatttt cattttccat atttttctac
      481 accttcctag ttactctact aggaaaacaa gggaaaattt gataaacttg agttgcgaaa
      541 tcaaagaaaa ccaaatcttg cgagcccttg ctatcttcct agcagggctt tttttattta
      601 aaaatagtcc ccttatcatc agcttgatta attaaaaatg taaccaaacc tgatttagtc
      661 attccatatt tttgtgccat tttttctagt ttgtcattcg attcaacagg taaagataaa
      721 gtcacttttt tcttctcaac ttcaaccaca aaatgcacct caattctctt caaaatctct
      781 tttacactgt aattatatta tacatacgac aggaatacaa gattttacaa aaaacttttt
      841 ttcacctcga aataggtgct taaaacgttc atataaaggt atttacaaga catttaatct
      901 ttttatctat ttggacaatg gacaatggac acatgggggg tgtcgtagtg cccccatgtt
      961 ttttcgctcc aaaaattccc atgttttttc gccccctgct cccactaaat ttccaaataa
     1021 taaaaccgtg ggctattcgc ccacacccaa caagcgcaaa gcgcttgacc ttgcctctga
     1081 aaagcaactt gataactgca ttcgtttctt tccgtcgtct tagcaaaagc taaacaactc
     1141 aaaaaaagag atcaagggta aatacactca ctacgttcgc ccttgacctc ttttatttcg
     1201 ctgtttttta cgcatttgcc gacgaaaagt aaacaatatg cagaattacc ctagttttga
     1261 taaaaaagcg cttagaacgc aaatatgagc ttctaacgac ttaattcatc cctatctcgt
     1321 gttttagttt cgtttctatg aattttttca aactctccac cttttacaaa ctctttaact
     1381 tcgctcataa ggttattcat cagcttttta gcttgtccaa cagttgcacc aagggtattt
     1441 tccataaact ggttaaaacc tttgtaaatg cccttaattt cgtttttaag cgacttattc
     1501 tctttctcta attcttcaag tgtttcaata ttctgattac tcttacgtac caacctattg
     1561 taatctttcg ctaattcgcg atatttctct ttaactctag tgatttcttt aggtaaatca
     1621 gtttccgcat aattttttag cttttcattt gctttatata gctcttcata gcttttaatc
     1681 actgcattta atttactttc agggataatt acatttcccg tttttcgttc ttcatttttc
     1741 ataaattcat gtcgcagctt accaatccca atggtttcgc cacttggtac tttgaccgtt
     1801 ttcgtttcgt cttttaaatc taaactttct ttcttgattg ttggtgcttt atcgttcgat
     1861 aacgctaaaa cttctgactt tcgctgttcc agcgtggtag ttatctcttt taattcgtcc
     1921 tttgcctttt tatattcagg caccgttaaa tttttacgct ctgacccttt ttcgccacgt
     1981 tcaagctcaa aaccacgctc atttaaatac tttggcaatt cgtcttgtac cgcttgtaag
     2041 gcttgacgat taaaaacagt ctttgctgat agcttgtgtt cgtcattaaa cggcacaatt
     2101 cctaagtgca tatgcggtgt cgtttcgtct aagtgaactt gagcgtagcg gatattatta
     2161 tcgccaaatt tgtccgcaaa atatgatttc gcagtatcaa aaaaatcttt aatttcttta
     2221 tcgtctttat ctttaaaaaa tgggttgtca gaagttatga tccattcgtt tattaataca
     2281 gcatcttttc tgacagcacg actacttgat ttattgtcgt taataaattg ctcaatatct
     2341 cgtttataat tttctgtccg attgaccaaa tcataattta aatgcgaccg ttcaacatca
     2401 atatctttgt tggaatgatt gtctgtattt ctctgattat gattacctac cccgactaaa
     2461 tttcctgatt ttaccttctg cattctcgcc actgcaaatg acatgtaaac actcctaact
     2521 tcggcacaac ttccatgtaa agtataaccc actagactta tttactacgt ttcataagtc
     2581 attaatgcgt gtgctctgcg aggctagttt ttgtgcaagc acaaaaaatg gact
//
LOCUS       DAIGQM010000135         2491 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.143, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000135 DAIGQM010000000
VERSION     DAIGQM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.143"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(366..1658)
                     /locus_tag="NOA48_002703"
     CDS             complement(366..1658)
                     /locus_tag="NOA48_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790917.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1932..2192)
                     /locus_tag="NOA48_002704"
     CDS             complement(1932..2192)
                     /locus_tag="NOA48_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790918.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          382 g          800 t
ORIGIN      
        1 gtatgggcta ctctgtgata cttattagcc attaaactat tttacccaca tagcatatat
       61 tttgaaatcg ttcattccgt aaattcaact aaatatgcct aaaaaaataa aaaatctaag
      121 atagaataag atttattcag tcttagatgg atttatagca actttttcgt aacaacttta
      181 aaaaatacga aaagaaagag ctgttttact ctgactacgt tgctaaattg tcgtttaatc
      241 attcatttaa accaaatctt tttttataga attcgtttta atcctcctga atccaaaaac
      301 tatgaaaacc gtaattaaat agttaagagt ttttaaccac cataattctc tcggctattt
      361 tgaaatcaga taaattttga tcggacacat agttgaataa acctaccgtt gttacggaag
      421 gtaaatcgca tacttttcat tctagaggag aaggtctcgt tgatcattaa ctgattaagc
      481 accatagccc agttttgaat tcgaccacct gaccacttcg cgtgtaattc tttcgtgcgt
      541 aaataaagta gttttaggag tgcattctca ttagagaacg ctcctttttt tgtgactttt
      601 ctgaagctgg agtggacact ttcaaccgca ttggtagtgt acataatttt tcgaatggca
      661 ctaccataat caaatagttg ttcaacatgt gcaaagttcc gtttccagac atctacagca
      721 ccagaataat gagaccaccg attttgaaaa ctgtcaaaag cagcatgtgc agcgtttaga
      781 gaagaagcac cgtagaactt tttcatatct cggcagactt ccttatagtc cttacttgga
      841 atatagcgca atgcatttcg aacaagatga acaatacagc gctgaacaat taccgatgga
      901 aagatcgctt ttgcgccttc ttcgaggcca gaaacaccgt ccatcgaaat gaaaaagaca
      961 tcttcgacac cacgtgcttt cagttcatca aatacttgca tccagcgatt tttagattct
     1021 gtttgattta accataatcc taaaatctcc ttatttcctt tgagatcata gccaagaatg
     1081 gtgtatacag catattcttt ggcttcataa ttttctcgta aagtaacata catacaatca
     1141 acgaatagaa aggcataaca ctttgctagg gggcgggctt gccattcttc caattcagga
     1201 aggacagcgt cagtgatatc tgaaatcatt tcatgggaaa tatcaaagcc ataaatagct
     1261 tcgacggttg cggcaatatc tcgttgactc attcctcgtg catacatgga aagaaccttc
     1321 ccttcgatgt cggagacatc tcgttttctc ttaggaatta actctggttc aaaggaagct
     1381 tcccggtctc taggaacatc aatagctact tcaccaaaac tggttttaag cgttttagtt
     1441 ccatagccat ttcgacggtt atcgtgttcc ttaggctctt tagaatgggc atcataacct
     1501 aaatgattat tcaattctcc ttgaagcatt ttttcaaaaa ggggcccaaa cacatctttc
     1561 aaagcatctt gcatgtcatc gacagattca ggttgatagg cattcagaat ggattcagct
     1621 aacttttcgg catcaggatt tcttttcttt ctagccatcg tgtaatcacc tcttgatctt
     1681 attgtagaaa aagaaaaacc gcgaagcaac cacctgccta ggattaatgg ttacttacac
     1741 ggtttatatt acactctcat cattaaaaaa gtatctttcg atattactaa acaatgaaat
     1801 tatctatttg aaatttaaat ctgataatat attgagtgtt ccaatgaggg ctttgatcct
     1861 attatccata tctttttcag ttttaatatt gatacacatt ataagaaaaa gaaacttttg
     1921 gttaatttat ttcatcccag tgcaaaatat aaaaaagtaa aatagaccat aggcaataga
     1981 ttaacaatta atataataca agcaaatatt ctattcattg tatttctgct ttcaaaaagt
     2041 tctaatattg aaagtataat tccacaaatg cctataataa gtatgggaat aagattagaa
     2101 aataacaccc cgagccaatc tgtgaaaatt actatattta ctaatatccc tattaacata
     2161 cctatcatat ttattaaatc aatttttttc attagatatt tctcctttat taaatctgaa
     2221 gtacttatat taaaataatt ctaaactatt tacctcaaaa agtgcaataa attatttctg
     2281 aacaataaaa tgatagtcaa aacaaaaaaa tattgttaat cgttcagagc catccgagag
     2341 tgtaaaatat tttgtgtaaa tgaaaaaatc catacaaaaa aggaaggcgc ttctgtagaa
     2401 taaagttaac gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca
     2461 gaaattgtgc aaactctagt cactaaaggc g
//
LOCUS       DAIGQM010000136         2484 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.144, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000136 DAIGQM010000000
VERSION     DAIGQM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.144"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(1014..1304)
                     /locus_tag="NOA48_002705"
     CDS             complement(1014..1304)
                     /locus_tag="NOA48_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790919.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="NOA48_002706"
     CDS             complement(1512..2204)
                     /locus_tag="NOA48_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0790920.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          458 c          349 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga
     2461 ttactgtatt tattacaaaa aacg
//
LOCUS       DAIGQM010000137         2419 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.145, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000137 DAIGQM010000000
VERSION     DAIGQM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.145"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..288
                     /locus_tag="NOA48_002707"
     CDS             <1..288
                     /locus_tag="NOA48_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790921.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(801..874)
                     /locus_tag="NOA48_002708"
     tRNA            complement(801..874)
                     /locus_tag="NOA48_002708"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(838..840),aa:Ile,seq:cat)
     gene            complement(1063..2082)
                     /locus_tag="NOA48_002709"
     CDS             complement(1063..2082)
                     /locus_tag="NOA48_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI0790922.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(2093..2299)
                     /locus_tag="NOA48_002710"
     CDS             complement(2093..2299)
                     /locus_tag="NOA48_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0790923.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          739 a          465 c          405 g          810 t
ORIGIN      
        1 gagacacaat tatggtttaa atttgaccct tcgaatagat ttatcaaaga tttttataaa
       61 gtatggaatt cagaagtttt ctttttagca atcgaagata gcttattaat caatctctac
      121 tattctaata agaactattt caaaattcct gctgcgaaaa ctagaatgaa gaaggatgta
      181 tactttttgt ttgatatcgt gactgacgtg ccggacgcac gtagcgatca tcggcgttat
      241 gactatataa agtatacttt cgttgatcca gaaagataca aagattaaag taggctacct
      301 aaaaaggtag cccggaacga attttatcac catacttgtg aaaggagata ttttttaagt
      361 tagtattaag attgtgtaat atgatgatat ctatatttta tagtatcagt gctataaaat
      421 caaaaataag tcactaatta actaccactc caattgtaag ccttttttct cacttttttt
      481 caaaaatatg gtatgccttt taatagcttc aaatataaaa gagtttaaag cgtaacacac
      541 ttatggggaa gtggcttggg gtgcgcttta aactcttctt tattatcatc tcacaattta
      601 acccaaatgt ctttctattt aaaaatcaaa gtaaaacttt tcaaatatac agaaatataa
      661 ctatgtgaaa catcctttca ttaatccata aaaggataca taaaaaagcc actcatttga
      721 gtggcaatga agaaaagctt tagcttgtat aatactcttc aaaaaattct aacacagaac
      781 gattcaaatg gctacgttaa tgtaccctgt aggactcgaa cctacgaccg gacggttatg
      841 agccgtctgc tctgaccaac tgagctaagg gtactggttg ttgccacata aagccataaa
      901 caatcaacca gtagaatgtg tggcaacaaa cctgttatcg catagcttgg agtgtgacta
      961 ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaatga tttttatagt
     1021 tgtcaatata gttatgtaat gctcctcaac gaggagctat ttttatcgtt taggaatatt
     1081 taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc cctctggatc
     1141 attcgttgcc cgcatcatga catagacttt cttattaggg aagttacgca tgttaaaaga
     1201 tacatgatag ccaacatttc cagaagtatt ataagcttga tttacatctg atctataaat
     1261 tccatcagct cttactcgag ctaattcttt cccagtattg taatccataa tgaagatata
     1321 ctcgtattta tagttagcaa tgtgccatcc agctacatgc aaatttgcat tttcgatttc
     1381 tccaaactga tcaatgtggg cgtaattcgt tccatctgtc agtgtaggat tagctgcacc
     1441 agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt catcggtaaa
     1501 tccatgagct aaatcatatg ctaatttttc tttacttacg cccatttcag aaagataacc
     1561 gtaaggatct gtatgatcgc cccagatgtt ttgtgttacc cataaatgcg atttgattcc
     1621 cggttggtta taaggagtgt ccaacgttaa tggaatacca tatttcattg ctgaatctct
     1681 agccaattca acgtatgcct tgtagttttt ctcaaacgtt gctttatcat gtgtgtgttg
     1741 taactcaatc tgcacaggac tgttggcatt agcatacgaa ccagcaccgt actgtacata
     1801 accaggttga ccgacttgat aaacaattcc gccgtctccc acaatataag cagtataagc
     1861 gctagtccat gaacgttgca tatactgcgc ttcattgcgt cctgttgctg tttcattagc
     1921 cgtttcatgc agtaaaatat actgattatt tgctacttgt gagctacctt catttgcgcc
     1981 caaattaaat tcattgttga tagtataggc aaatccgtta attggcaata aaaaaagagc
     2041 cgttaacagg ctcatcgcag taatagtaat tttctttttc atatctatcc tcctatttat
     2101 ctgatgaaat tttcttatac gttcgatttg atacacctaa aatactccct agaaatgctc
     2161 caaaacctgt aataatcatc accgttatat ctgtgtaccg ccagttaaca ccttttccga
     2221 caagaccgac aaaagtcgct aaagcgggga taactactat agcgatccat ttcaaaatat
     2281 caaaggttct attgttcata ctatccacct cccttcattg gttgggctac tttctttttc
     2341 aatcgcttgt tttcttctat caatatttct ctttctgaaa gcaaggcatc aatttgcccg
     2401 tccagttgtt caattttat
//
LOCUS       DAIGQM010000138         2401 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.146, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000138 DAIGQM010000000
VERSION     DAIGQM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.146"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            207..2069
                     /locus_tag="NOA48_002711"
     CDS             207..2069
                     /locus_tag="NOA48_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0790924.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..2401
                     /locus_tag="NOA48_002712"
     CDS             2069..2401
                     /locus_tag="NOA48_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0790925.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          867 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
     2401 a
//
LOCUS       DAIGQM010000139         2126 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.148, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000139 DAIGQM010000000
VERSION     DAIGQM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.148"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..74
                     /locus_tag="NOA48_002713"
     CDS             <1..74
                     /locus_tag="NOA48_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790926.1"
                     /translation="NQICEITNVSRASLYRKLSEVNN"
     gene            288..983
                     /gene="vanR"
                     /locus_tag="NOA48_002714"
     CDS             288..983
                     /gene="vanR"
                     /locus_tag="NOA48_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0790927.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            961..2115
                     /locus_tag="NOA48_002715"
     CDS             961..2115
                     /locus_tag="NOA48_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0790928.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          713 a          397 c          452 g          564 t
ORIGIN      
        1 taaatcaaat ttgtgaaatt actaatgtat ctagggcttc attatacagg aaattatcag
       61 aagtgaataa ttagccattc tgtattccgc taatgggcaa tatttttaaa gaagaaaagg
      121 aaactataaa atattaacag cctcctagcg atgccgaaaa gccctttgat aaaaaaagaa
      181 tcatcatctt aagaaattct tagtcattta ttatgtaaat gcttataaat tcggccctat
      241 aatctgataa attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa
      301 tacttattgt ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg
      361 agaattatac ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt
      421 ctgagattga ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct
      481 gtcaaaaaat aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag
      541 aggtagataa aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc
      601 gcccactgga gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg
      661 gagtaaagga gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca
      721 cccatgagtg ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac
      781 tgcgaatcct ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga
      841 tatggggcga cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt
      901 tgcgcgaaaa aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg
      961 ttggttataa aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac
     1021 atgtatatcg ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg
     1081 atccgaggga aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat
     1141 cacctggacg cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt
     1201 tatgtggcga ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca
     1261 aaatactttg acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa
     1321 attgagcttt ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact
     1381 ctggaaaagc gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg
     1441 tacttggcgc acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt
     1501 gacgaggctc cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac
     1561 aaagcgtatc gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta
     1621 caaacgataa cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc
     1681 gatgaatttt atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag
     1741 gatctgaccg tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa
     1801 aacgccgctg catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg
     1861 gatgtggtgt caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc
     1921 atatttgaaa agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga
     1981 cttggattgg cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa
     2041 agcaatgata actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat
     2101 aaaaggaggt cctaagagat gtatat
//
LOCUS       DAIGQM010000140         2112 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.149, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000140 DAIGQM010000000
VERSION     DAIGQM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.149"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(193..291)
                     /locus_tag="NOA48_002716"
                     /pseudo
     CDS             complement(193..291)
                     /locus_tag="NOA48_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(556..1011)
                     /gene="tnpA"
                     /locus_tag="NOA48_002717"
     CDS             complement(556..1011)
                     /gene="tnpA"
                     /locus_tag="NOA48_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCI0790929.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYRRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1254..2112
                     /locus_tag="NOA48_002718"
                     /pseudo
     CDS             1254..2112
                     /locus_tag="NOA48_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          670 a          402 c          375 g          665 t
ORIGIN      
        1 acttcaatgt tatgagacaa actgtctata agaatcaatt tccacccatt tcatcacttg
       61 ttaaaagttt atgatccttt tgatttttat attaatttat ctgtatttaa tacagatttt
      121 atttattagt tcatctgcct attgtatttt attttgttgc cttaccatct gaagtaaata
      181 tactcttaat tgtcaaatta agttagacag atcatcaata cttacgtaac tcaaaaatac
      241 ttccaaaggt gttcgataat ccagtgattt tctaggaaga ttatttctgc gccagcattt
      301 tctaatgttt gaatttgtgt tttgtaatct tggttgcttg tgctaattct tgaatagccg
      361 taaattgcca aaatttcatc accctttctg gacataagtt tctgacacca gttaaaatca
      421 agtctatcag taacccatac acccgtgagg acgggtgtat ttttaatccc cctagaaggg
      481 gtcgacactc gctgcccctt aaaaggggat ttttaaaaga ccgccaactg ctcatcttca
      541 ctcacttact tctctttatt ttttaaatgg ttctacgtac tctcttttac ttataatata
      601 tcgaatgcga tcatcagctt cttgttcacg gatgtatttt tcatttgtct tttgattcaa
      661 tccgactgta ctcacatagt atctcttcga ccaaaaggat ttgtttccgt atttatattt
      721 gagatttgcg tgctgctcgt ggattagtac cgcactacga cctttcagat accccataaa
      781 actggatata catatttttg gtggtactcg aacaagcatg tgaatatgat ctagcattgc
      841 atgtgcttct atgatttcca catctttcat ttcgcacaac ttcctaagta tttttccaag
      901 atcttttcgt aattgcccat agattacttt tcgtcgatat tttggtgtaa aaataatatg
      961 atacttacaa ttccaacgag tatatgctaa acttttatcg tcatttgaca tgaaaaaact
     1021 cctttcgatc tgatgagcgg ttggtagcca ctcactagta tatcgaaagg agtttttatc
     1081 gctaaagata cttcttccac gcgtagaaac gcgcggtttt cttgtttcgc acgctttacg
     1141 cacaaaactg actgaagtca ttaagaaaat aaaagggtct aaaactttta agttttgtac
     1201 cgacccccaa aagttagacc aaaaaatcta acttttggag gtcggtattt tttatagcta
     1261 agtatacttt tgaacttaaa ttaaagatcg ttcatgatta tttggatggt aaaggcggaa
     1321 gtgattatct ggcaaagaag tattccatta aggttccatc acaagtgaag cgctggatca
     1381 atgcctatca agaatttggt gaagagggtc tagtaagaaa gcgacaaaag aaaaaatatt
     1441 ctgttcaatt taagctggat gcgatagagt tatatctaac aagtgagctg tcctatcgtg
     1501 aagttgccaa cacacttaac atgaacaacc ctaatttgat cgctagttgg atgcatcaat
     1561 tccgtgaggg tgggatcgat ggactctcaa aaacgaaagg atgtccacct atcttgtcta
     1621 agaaatatga acccaaaaat aagaaaaaat ctacaactaa agcaacgtct aaagaacgtg
     1681 aacgcatcga ggagttggag aaacgagtcc gttcccttca aattgaaaat gcctctttaa
     1741 aagaattgag gaagctgcga aaacaggaag cccaacaacg acgaatgaag caatcgcacg
     1801 aatcatcgca agcctccgag gaccgtttaa attagttgag cttctagaaa ctttaaagtt
     1861 ccctaaggca acctttatgt actggcaaaa acgattggac cgtaaaaatc cagatcaaga
     1921 gattgaagcg gaaatgctta aaattcggga gaagcacaag gattatggct gtttacggat
     1981 gaccaatgaa ctaagaaacc gcggtttctc tatcaataaa aagaaagttc agcgcctgat
     2041 caagaagcta ggaataaaag taacgacata cacacgtaaa tcacggcgct acaattctta
     2101 tcgaggacaa gt
//
LOCUS       DAIGQM010000141         2056 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.150, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000141 DAIGQM010000000
VERSION     DAIGQM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.150"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            493..714
                     /locus_tag="NOA48_002719"
     CDS             493..714
                     /locus_tag="NOA48_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790930.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="NOA48_002720"
     CDS             715..972
                     /locus_tag="NOA48_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790931.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="NOA48_002721"
     CDS             complement(1108..1710)
                     /locus_tag="NOA48_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0790932.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="NOA48_002722"
     CDS             complement(1777..1932)
                     /locus_tag="NOA48_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0790933.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAIGQM010000142         1989 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.151, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000142 DAIGQM010000000
VERSION     DAIGQM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.151"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..211
                     /locus_tag="NOA48_002723"
     CDS             <1..211
                     /locus_tag="NOA48_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCI0790934.1"
                     /translation="NTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVIPENWR
                     KSLQNDQLLKTISQRFCDTVLSQRI"
     gene            280..546
                     /locus_tag="NOA48_002724"
     CDS             280..546
                     /locus_tag="NOA48_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0790935.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            536..805
                     /locus_tag="NOA48_002725"
     CDS             536..805
                     /locus_tag="NOA48_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0790936.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            1512..1961
                     /locus_tag="NOA48_002726"
     CDS             1512..1961
                     /locus_tag="NOA48_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI0790937.1"
                     /translation="MYNEKKIVDIVTLKMVVAEKSLPIEKVRSSFEVGNWLIEEIGDY
                     AQEHPALLCLNTKNEITHFSIVHVGTLNQSVAHPRCIFQRAILANAARIMISHNHPSG
                     NTTPSENDIQFTNRLIKAGEVMGIELLDHIIVGQKKYLSLREEGYWN"
BASE COUNT          649 a          380 c          432 g          528 t
ORIGIN      
        1 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
       61 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
      121 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
      181 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
      241 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
      301 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
      361 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
      421 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
      481 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
      541 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
      601 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
      661 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
      721 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
      781 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
      841 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
      901 ggtttctgct tttttatttg gtcttgaaga agaaaacgag tgatctgtgg caaagaaaga
      961 aacaaaaaaa ggacaaaact gttgcttcgc ctgcggtgca gtcgcccctg gctcaaagcg
     1021 caacagtttt tttggctagt ggcaaggtct aactgcttgt tggctacgtg ccttcgccag
     1081 tcgcagttac ctttgttggc tgcgttcctc cgccaagtcg gctgacctca ccatttttgc
     1141 ctacgcgaaa aggccaaaag gatttaaagg aatccgtcga agcatagctc caacttctcc
     1201 ggatcaaaaa gcggtaggaa cccatgccgg gttcccttag ttgaattttt tggttttgcg
     1261 ctacattttt accattgcgg acgccgacta gctgcgaaat agaatgagcc tccaggctac
     1321 gcctactcat tctacttctc gcaagtggct tcgccaggcg gcaagggcaa gcaatgtgct
     1381 acgcaccctt gccgcctgac tgctgcatgg taaaagcttc gcaacaaaac gcaaaaaatt
     1441 cagcctttgg ctaccgctgt gtagcgcaaa gaccaaaagg agaaggtcaa aaaatggaac
     1501 caactacagt tatgtataac gaaaagaaaa ttgttgatat tgtcacactc aaaatggtag
     1561 tagccgaaaa aagtttgcct attgaaaaag tgagaagttc ctttgaggtt ggaaattggt
     1621 tgattgaaga aattggtgac tatgcacaag aacaccctgc gctactttgt ctgaatacga
     1681 aaaacgaaat tacccatttt tcaatcgttc atgtgggaac attgaatcag tcagttgctc
     1741 acccacggtg cattttccaa cgtgctatat tggcaaatgc cgctagaatt atgatttcac
     1801 ataatcaccc ttcaggaaac acaacaccta gtgaaaacga tattcagttt accaatcgat
     1861 taataaaagc cggtgaagtg atgggcattg aactacttga ccatattatt gtcggtcaaa
     1921 agaagtacct ttccttacgt gaggaaggtt attggaacta acgattaaga ctgcctgata
     1981 ataaggcag
//
LOCUS       DAIGQM010000143         1858 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.152, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000143 DAIGQM010000000
VERSION     DAIGQM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.152"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..614)
                     /locus_tag="NOA48_002727"
     CDS             complement(<1..614)
                     /locus_tag="NOA48_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790938.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQV"
     gene            655..1347
                     /locus_tag="NOA48_002728"
     CDS             655..1347
                     /locus_tag="NOA48_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0790939.1"
                     /translation="MDVEMLIDKYQLNDSEAEVLRFMKKNRQSLKNIGIRDVAKASYV
                     STATIINMAKKIGYSGYSELVFALGNSQSDITMPSTFSNEEKEAFIHLMSAYRDKRIM
                     ILGSGFSQNLANYFSESLNLYGFRATANSHLEFLRQQVQQDILLFIISNSGDTVRLAE
                     LAKIANDHFIDVIAFVGQKNSKIGTLATLTISTETYIPQKISDYQPNLFFGTTLNQFE
                     LLLSAALKAIYK"
BASE COUNT          571 a          348 c          331 g          608 t
ORIGIN      
        1 acttgccaag gattaaatga aaacgtactt ggcacgacgt gatctggatc ataggtctcg
       61 atgatttttt cgtattgttc cttgtagtca ttatcaactt ttgcttgggg gatcacttta
      121 cttgcttcat gcaaaaagtg ttctgaacca cgccccattg cctgtccccg aacagtatgt
      181 ttatccaacg caatatcagg aatttctgga atatatccca tagcgaaact cttgataaca
      241 atgttcttaa gtaaatccga tgaacgatct ttttcagatt ggcataggta acgaatcgcg
      301 tggaaaaaat acatcgcacg atcggattca ttgtattgga attctttgcg catggcgttt
      361 aagttattga tcatgatggc ggccatagga ttgcccatgc ccacatcctc aacactgatc
      421 gccaatagcc ttctccagag tttctcttca aattgtggtg aggtgatata catttcataa
      481 gcaaattcac atgcttcttt ttcttttcct cgacgaatcg atttctgtaa tgctgagata
      541 gcttcatctc cacgtaagcc gttacgggta gtcatttttg accacggatc ttgaataaat
      601 ttcgtttctg tcataatata atactcctat tagataaaat ttgaggtgaa tcttatggat
      661 gttgaaatgc ttatagataa ataccaactg aatgactcag aagctgaagt cttacgattt
      721 atgaaaaaaa atcgtcagtc tttaaaaaat attgggattc gtgacgttgc caaagcatcg
      781 tatgtttcta ctgcaacgat tatcaatatg gcgaagaaaa ttggatattc cggttatagt
      841 gagttggtat ttgctctagg aaacagccaa tctgacatta cgatgccaag cacattctcc
      901 aatgaggaga aggaagcatt catacattta atgtctgcgt atcgcgataa acggattatg
      961 attcttggct caggtttttc gcaaaatcta gccaattatt tttcggaatc tcttaatcta
     1021 tatggatttc gtgcgacggc caatagtcat ttagaatttc ttagacagca agtgcaacaa
     1081 gatattctgc tttttattat ttccaattct ggtgatacag ttcgattagc cgaattagct
     1141 aaaattgcga acgatcactt tatcgatgtg atcgcatttg ttgggcaaaa aaattcaaaa
     1201 atcggtacgc tggcaacatt aaccattagc acggaaacct atattccaca aaaaatatct
     1261 gattaccaac caaatctttt ctttggcacg acactgaatc aatttgagct tttgttgagc
     1321 gcggcgctga aggctattta taaatagaag aacgctgtgg ccactgtttc ttcaaaatct
     1381 agtataaaga atcttcttta gaatgtaatt gttttctgtg tgttctgaac atgtttagga
     1441 atttccaaac ttgtttagaa aactttctca ttccctccgc tgtagaattg aactcacata
     1501 aaaaacatct aaaccaaaat atctacaagc ttggaaagga taataggttg ttattaaaaa
     1561 taatttttat tcctgaacct gaataattca tagctttaat tctttggcac attttattga
     1621 aatatgtatc actaatatcc ctatcaactg attttgacta aaaagttact tcaaacattc
     1681 actgttcaaa aatattgagg aataaatttt gggtgtaagg cattttgagc atacttctcc
     1741 ctggataact tcccagtaaa aaaatcgtta gattgttgga ttagatccat tgactgcctc
     1801 gcctcaggcg agcaaagacc ctgtagaatt cattctgata cacatgataa ctagataa
//
LOCUS       DAIGQM010000144         1794 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.153, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000144 DAIGQM010000000
VERSION     DAIGQM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.153"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..446
                     /locus_tag="NOA48_002729"
     CDS             <1..446
                     /locus_tag="NOA48_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI0790940.1"
                     /translation="LCVELNNEVSQSTDQTPDERWQTNEKEHLHPYQKNLLNPYFEDF
                     IRRKVTKEEMVIFRKCRYSVAPRYIGKEVEIELSDKEDQVQIYYNGELIRSHPLTTKQ
                     LNYHEEDYFQILKSDVMSHKEDDGIRAYTRESLKQYDLVEVADEE"
     gene            436..1176
                     /gene="istB"
                     /locus_tag="NOA48_002730"
     CDS             436..1176
                     /gene="istB"
                     /locus_tag="NOA48_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCI0790941.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            1586..1750
                     /locus_tag="NOA48_002731"
                     /pseudo
     CDS             1586..1750
                     /locus_tag="NOA48_002731"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          578 a          369 c          351 g          496 t
ORIGIN      
        1 acctttgtgt tgagttaaat aacgaggttt ctcaatcaac tgatcaaaca ccagatgaac
       61 gttggcagac gaacgaaaaa gagcacctgc atccatacca aaaaaacctt ttgaatccct
      121 attttgaaga ctttattcgc cgtaaagtca ccaaggaaga aatggtcatt ttccgtaaat
      181 gcaggtactc tgtggcgcct cgctatatcg gtaaagaagt cgaaatcgaa ctctccgata
      241 aagaagacca agtacaaatc tattataacg gagaactgat tcggtcgcat ccattaacga
      301 caaaacagct gaactaccac gaggaagact atttccaaat cttgaaatcc gatgtcatga
      361 gtcacaaaga agacgatgga atcagagcgt atactcgtga aagtctcaag caatatgatc
      421 tggtggaggt tgccgatgaa gaatagccat taccaagaac tgatgaccaa cttagagact
      481 cttggtttga atcatatgcg ggaatatgtt cctaactaca tcgaagtggc caatcgagag
      541 gagctttctt taacggaagc tcttctcgag ctgacacgca gagaagttga tcatcaaaat
      601 aagcaaaaaa tgaatcgtgt ggtggcacgc gcccgctttt ccaagagaac cagcctggaa
      661 gagtttgatt ttgccttcca gccaagtatc aataagcgcg aagtgctaga cttaaggcac
      721 atgggctttg tggaaaaaca tgagaacttg gtttttatcg gcagtcctgg tgtaggcaag
      781 acacatctga cgattgcatt gggaatcgaa gcctgtcgtc aaggctatcg gacactattc
      841 atcacctgtc atgagctgct tttgcgtctg cgaacagcct atgaaaaagg taccctagag
      901 cgtgttctca aacgatacgc tcgctatgac gtcttgatta ttgatgagat tggctatctt
      961 ccgattcaaa aacaggaagc tgatttattc tttcagcttc ttgccatgcg ctatgaacac
     1021 cgctctacga tcattacgac gaacattgtc ttatctcgtt ggggggagtt gttccaaagt
     1081 tctgagatcg cagctgccat ccttgaccgt ttagtacatc acgtcaaggt gttcaagatc
     1141 acaggcaagt cttatcgtat gagagacaag atctaaagtg tcgattgtcg acaattacta
     1201 ttgccgaaaa cctacatttt tatcctgccc aaaacctaca attttaagct gcccttgaca
     1261 tcaaaaagac acttcacaag ctaagtgcta tcgacaattg aaacctttgt ataaattact
     1321 tctataatca gatgacgagt tggattatac aacattcaag aaatggcaga attttcaatg
     1381 gcgctattta acagaaagtg aagtagttga ttgtctaccc tcaatctctt atgaacttaa
     1441 aatggcttag cagtattatc aaaagctgct taacaattat cacaagaaac agctagctac
     1501 ttcgagaaat gaccaaagaa gttccctcga aacttcacta tcttaaaaag cctttttcat
     1561 atctgaaaaa ggcttttaac tagcattttc gaaaaagtat tttaatacaa aattagagaa
     1621 tcttcgcaca catatcaaaa cattgaaacg atttgcttat ggattttgca gttttaccaa
     1681 tatgcgcttg tggatttttc taatcaacgg gttaataagc tatgcattaa aagctagtaa
     1741 atcttactaa ctttgttgat cataaatgac cttatcagcc cgatttgaca aaga
//
LOCUS       DAIGQM010000145         1617 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.154, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000145 DAIGQM010000000
VERSION     DAIGQM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.154"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..711
                     /locus_tag="NOA48_002732"
     CDS             <1..711
                     /locus_tag="NOA48_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0790942.1"
                     /translation="PPNSLSTEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGG
                     FLGYVANRGNKYTFELAQSFSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVT
                     QYLVTTEFDDDTVQAIMDEALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPR
                     TAQQQYDVTQHIPLSEAQAGDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYAD
                     LTSPYWQQHLVGAGRIKQ"
     gene            708..>1617
                     /locus_tag="NOA48_002733"
     CDS             708..>1617
                     /locus_tag="NOA48_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0790943.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNG"
BASE COUNT          534 a          307 c          344 g          432 t
ORIGIN      
        1 ccacctaatt cattgagtac agaagaatcc attaagcaag gtgtgaagta tttcagtgaa
       61 ttattagcca gtagcgaaag gctcagtgta gatttagaat cggttatcca gtcctacaat
      121 tatggtggtg gtttcttagg gtatgtggct aatcgtggaa ataaatatac ctttgaactg
      181 gctcaaagtt tctcaaaaga gtattcaggt ggcgaaaaag tgtcttaccc caatcccata
      241 gccataccta tcaatggggg ctggcgatac aactatggca atatgtttta tgtgcaactg
      301 gtaacgcagt atcttgtcac aacagagttt gatgatgata cggtacaagc catcatggac
      361 gaagcactga aatatgaggg ctggcgatac gtttacggtg gagcttcccc gactacttct
      421 tttgattgta gcggactgac acaatggacg tatggaaaag ctggaattaa cttaccacga
      481 accgcacaac agcaatatga tgtgacccag catatcccac tatcggaagc acaagctggc
      541 gatttggttt tctttcattc tacctataac gctggctctt atattactca tgttgggata
      601 taccttggca ataaccgtat gtttcatgca ggcgacccaa tcggttatgc cgacttaaca
      661 agcccctact ggcaacagca tttagtggga gcaggacgaa tcaaacaatg agaaaggaag
      721 atttaatgat gaaatttaga aaaaatcaga ataaagaaaa acagatacca aaggaaaaga
      781 aacctcgtgt ctataaggtc aatcctcata aaaaggttgt gattgccttg tgggtacttt
      841 tagggcttag tttcagcttt gcgatattca agcactttac agctatagat actcatacta
      901 ttcacgaaac aactatcata gaaaaggaat acgttgatac tcatcatgta gaaaattttg
      961 tagagaactt tgcgaaagtc tactattcat gggagcaatc cgataagtcc attgataatc
     1021 gaatggaaag tctaaaaggc tatctgacag atgaacttca agctctcaat gttgatacag
     1081 tacgcaaaga tattcctgta tcgtcttctg taagaggatt tcagatatgg acggtagagc
     1141 caactggcga caatgagttt aatgtaacct acagtgtaga ccagctcatt acagagggag
     1201 aaaatacaaa gaccgtccac tctgcttata tagtgagtgt ctatgtagat ggttctggaa
     1261 atatggtact ggttaagaat ccgaccatta ccaacatacc taagaaatca agttataaac
     1321 caaaagccat tgaaagtgag gggacggttg attccattac aaccaatgaa atcaatgagt
     1381 ttttaacgac gttcttcaag ctctatccta cagcgacagc cagtgaactt tcctactatg
     1441 tgaatgacgg gatattaaaa ccaatcggaa aagagtacat ctttcaagaa ctggtaaatc
     1501 ctattcacaa tcgtaaggat aatcaagtca cggtatcgct gacagtggag tatatcgacc
     1561 agcagaccaa agcaacgcag gtatctcaat ttgatttggt acttgaaaag aacggga
//
LOCUS       DAIGQM010000146         1568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.155, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000146 DAIGQM010000000
VERSION     DAIGQM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.155"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..433)
                     /locus_tag="NOA48_002734"
     CDS             complement(<1..433)
                     /locus_tag="NOA48_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0790944.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAVRIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGV"
     gene            747..1169
                     /locus_tag="NOA48_002735"
     CDS             747..1169
                     /locus_tag="NOA48_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790945.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1179..1382
                     /locus_tag="NOA48_002736"
     CDS             1179..1382
                     /locus_tag="NOA48_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790946.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
BASE COUNT          534 a          245 c          260 g          529 t
ORIGIN      
        1 aaactccatt tgctttcgca attttaatgc cttgcgcctg gcgtcgttta gattcggtac
       61 gctcttgttc agcgatcatg gccaaaattt ggatgatcag atccttaatg aatttatcca
      121 ggagagggtt gccaattgct tcagccatga tcggtagact ggtgatgatt agctgtacgt
      181 ttttcttctt taggtaattg actgaagcga tgatctcgtc gtaatttctt ccaagtcgat
      241 caatagcttc cacaataaaa atgtcttgat ctcggacgaa atccaatgct tcttggaaaa
      301 caggtcgatg agtaatcgtt gcgcccgatt gtttctcgat gaaaattctc actgcaccga
      361 attttttcat ttcttcaatc tggcgttgtt cattttgatc gatggatgag acacgtatgt
      421 atgcaactct caaaattttt acctactttc tgcaactatt taaaatacac cctaatcata
      481 cacgataaaa ccagattttt caatgttgtg gtcgtgtcta gttagggtat accttatata
      541 gacaaaaact aatgatggag gaaatagtat gtgtcacttt tctttttaaa tggcaatatt
      601 ttttgtaaat aaatgtcaat caagaaaatt taaacgatta tgacattaaa aatatatttt
      661 atgaattttc tagtatataa cttgatttat ctgttaagat ttattaagaa aacgttttct
      721 tatttttgat ttcgaggtga tagacaatga aaaataagtt tattttatct ttaggtattt
      781 taactattgg aattagtgta actggaacta caattcctac atttgctgat agtacaaatg
      841 aaccaactac tgtagtagat aataaccaag aattaactcc tttagatagg aacggaatag
      901 ccattggtaa cccaactaac gacttaactg ttactgaaaa ttatttaata gtttctccat
      961 tacttgctcg agcagcttct aaaacgatac gagtgacagg aacgatgatt tttgataaag
     1021 ttggttggcc ttctagacct cctcaatcac ggaattggaa agaaaaaaga aatggttatt
     1081 ggtactatgg aaaattgtat ttacaaagtt ataaatcagc tggaaacaat tggattgcga
     1141 cttattcagg aaccttaact agaaagtagg gattttttat gccagaattt gtgaacacac
     1201 caaattttta tcaagatagc gatattctaa gtaaaattaa tttaccgaaa gaagaatcag
     1261 ctttacaagt tcagcgaact ttacaggaga cacaaaaaat tcaaaaatca atttctaatc
     1321 tagaagattc tgaagaaaaa agaaaaaaaa gagaccaaaa aacatatcaa aaagaaaaat
     1381 aatgatttta aaaaaagagt gtctagtcga cattcttttt ttctaattga aagtgttcat
     1441 aaaatcaccc atttctggac actttctgtc atttttatat ttaattggca cagttttttc
     1501 taattatttg tcatattcat agtcaactat agctacaaaa gcaactaatt ttggagatag
     1561 attgagat
//
LOCUS       DAIGQM010000147         1519 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.156, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000147 DAIGQM010000000
VERSION     DAIGQM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.156"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..1469
                     /locus_tag="NOA48_002737"
     CDS             <1..1469
                     /locus_tag="NOA48_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCI0790947.1"
                     /translation="LTTEIQLLNEKVNYLTNKLFGRSKETLFEETNGQLNLFSDEEIS
                     VSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKEHLLPLEEQFCEHCGSQMKDIGR
                     TKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVA
                     ETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQ
                     EEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFT
                     GYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVL
                     EKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEP
                     IFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPV
                     KYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFSRN"
BASE COUNT          509 a          273 c          317 g          420 t
ORIGIN      
        1 atcttacaac tgaaatccaa ctattgaatg aaaaggtcaa ttatttaacc aacaaattat
       61 ttggacgctc taaagagact ctctttgagg aaacgaatgg gcaattgaat ctttttagtg
      121 atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca gtaaaaggac
      181 atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata acagagaaag
      241 aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag atgaaagata
      301 tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg gattgtctca
      361 cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt tcttctttta
      421 aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat agtttagtgg
      481 cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa gagaactatt
      541 ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg catattaaag
      601 cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt aatcaagaag
      661 agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa acagatacct
      721 attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat tatcaccacg
      781 acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca gggtatttac
      841 actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc tattgtttcg
      901 cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac acggatattc
      961 ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag aaatggaaag
     1021 acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca ttatttattg
     1081 ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg gatgcagccg
     1141 ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat ggtcgtttag
     1201 aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga cggaaaaatt
     1261 ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg agtgtatata
     1321 aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta tttgataaga
     1381 taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct tggaacaagg
     1441 atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt ctattctata
     1501 ggtcgggtta tttgacgta
//
LOCUS       DAIGQM010000148         1425 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.157, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000148 DAIGQM010000000
VERSION     DAIGQM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.157"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(74..158)
                     /locus_tag="NOA48_002738"
     tRNA            complement(74..158)
                     /locus_tag="NOA48_002738"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(122..124),aa:Leu,seq:caa)
     gene            complement(176..247)
                     /locus_tag="NOA48_002739"
     tRNA            complement(176..247)
                     /locus_tag="NOA48_002739"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(213..215),aa:Gln,seq:ttg)
     gene            complement(257..329)
                     /locus_tag="NOA48_002740"
     tRNA            complement(257..329)
                     /locus_tag="NOA48_002740"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(294..296),aa:His,seq:gtg)
     gene            complement(391..475)
                     /locus_tag="NOA48_002741"
     tRNA            complement(391..475)
                     /locus_tag="NOA48_002741"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(439..441),aa:Leu,seq:caa)
     gene            complement(496..566)
                     /locus_tag="NOA48_002742"
     tRNA            complement(496..566)
                     /locus_tag="NOA48_002742"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(532..534),aa:Cys,seq:gca)
     gene            complement(612..683)
                     /locus_tag="NOA48_002743"
     tRNA            complement(612..683)
                     /locus_tag="NOA48_002743"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(649..651),aa:Gln,seq:ttg)
     gene            complement(695..767)
                     /locus_tag="NOA48_002744"
     tRNA            complement(695..767)
                     /locus_tag="NOA48_002744"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(732..734),aa:His,seq:gtg)
     gene            complement(770..843)
                     /locus_tag="NOA48_002745"
     tRNA            complement(770..843)
                     /locus_tag="NOA48_002745"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(809..811),aa:Trp,seq:cca)
     gene            complement(850..930)
                     /locus_tag="NOA48_002746"
     tRNA            complement(850..930)
                     /locus_tag="NOA48_002746"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(894..896),aa:Tyr,seq:gta)
     gene            complement(932..1007)
                     /locus_tag="NOA48_002747"
     tRNA            complement(932..1007)
                     /locus_tag="NOA48_002747"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(972..974),aa:Phe,seq:gaa)
     gene            complement(1043..1115)
                     /locus_tag="NOA48_002748"
     tRNA            complement(1043..1115)
                     /locus_tag="NOA48_002748"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1080..1082),aa:Asp,seq:gtc)
     gene            complement(1125..1197)
                     /locus_tag="NOA48_002749"
     tRNA            complement(1125..1197)
                     /locus_tag="NOA48_002749"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1162..1164),aa:Val,seq:tac)
     gene            complement(1213..1284)
                     /locus_tag="NOA48_002750"
     tRNA            complement(1213..1284)
                     /locus_tag="NOA48_002750"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1249..1251),aa:Glu,seq:ttc)
     gene            complement(1299..1388)
                     /locus_tag="NOA48_002751"
     tRNA            complement(1299..1388)
                     /locus_tag="NOA48_002751"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1352..1354),aa:Ser,seq:gga)
BASE COUNT          412 a          367 c          324 g          322 t
ORIGIN      
        1 atttggaggt aattacataa aaacaaaaaa aatatagcaa ctctctataa gaaagttgct
       61 atattgataa ttataccggc ggccggggtc gaaccggcac gtcctcaacg gacactggat
      121 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa atttaaaaat aataactggg
      181 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
      241 taccccaaga ataaagggcg aatgatggga atcgaaccca cgaatgccgg agccacaatc
      301 cggtgcgtta accacttcgc cacattcgcc atcataaaag atgttattta atttctcaat
      361 aaaaaactaa gatgaagaca tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc
      421 ctcaacgggc actggatttt gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt
      481 gatttattag tactaaggcg gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct
      541 ctgccttacc acttggctat accgccatta tactattatc aatctataaa ataaagaata
      601 aattatagaa actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
      661 ccttaccgct tggctatacc ccaagaataa aaagggcgaa tgatgggaat cgaacccacg
      721 aatgccggag ccacaatccg gtgcgttaac cacttcgcca cattcgccat ggcaggggca
      781 gcaggaattg aacccacact aacggttttg gagaccgctg ttctaccttt aaactatgcc
      841 cctataaaat ggaggagagt ggattcgaac cactgaaccc taaggaacgg atttacagtc
      901 cgtcgcgttt agccacttcg ctactcctcc atggtggcgc gggacagaat cgaactgccg
      961 acacacggag cttcaatccg ttgctctacc aactgagcta ccgcgccata ttttaaaatt
     1021 attaattgaa taacaagaac gacggttccg acgggaatcg aacccgcgat ctcctgcgtg
     1081 acaggcaggc atgttaaccc ctacaccacg gaaccagttc attatggagg ttaacgggat
     1141 cgaaccgctg accctctgct tgtaaggcag atgctctccc agctgagcta aacctccaac
     1201 attcaattaa aatgacccgt acgggattcg aacccgtgtt accgccgtga aagggcggtg
     1261 tcttaaccgc ttgaccaacg ggccaggtaa atttgctacg gagagtaagg gattcgaacc
     1321 cttgagacag tttggcacca tctacatgat ttccaatcat gctccttcgg cctctcggac
     1381 aactctccag agtgaaagaa gctcaatact ctttctcaaa atgag
//
LOCUS       DAIGQM010000149         1421 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.158, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000149 DAIGQM010000000
VERSION     DAIGQM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.158"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            88..1383
                     /locus_tag="NOA48_002752"
     CDS             88..1383
                     /locus_tag="NOA48_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0790948.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          448 a          280 c          267 g          426 t
ORIGIN      
        1 acatcttttt tgtataaaaa aatatagaaa agacaccctg aaatccttta gaattaattt
       61 ggctaccaat tcataggagg attcaagatg tctcatactc agcttatcaa agatacccta
      121 aatattctag acctaaatat ctatttcgag gaaaattgtt taactaaaga aaaatacaaa
      181 gggcaaattt gcttgattta caaaggaact cttctgtaca agccagaaga gtgttcccat
      241 tgtctttgtg tcgtcccctc taggatcatt cgttggggga cgacaaccgt tcggttgtta
      301 ctgaatgatg tgtctgagta tcgcacttat ctggagctga agaaacaacg atttaaatgt
      361 aagtcttgcc aaagaacatt cgtagcggat acctctgttg ctgaaaaaca ctgtttcatt
      421 agtcaaaaag ttcgttggtc tgtcattgct cgcttaaaag agaatacttc catgacggaa
      481 atcgctcgtc agaaaaatat ttccacttct tcggtctatc gtgtcatgaa gcgattctac
      541 cgcccattga atcctttcaa acagactttg ccaaaggtct tatgctttga tgaattcaaa
      601 tcggttcgaa gtgttgccag tgcaatgagt tttatcatga tggacggaca aagccatgca
      661 ttattggata ttgtcgaaaa tcgacgcttg ccttatttag aacgctattt ttctcggttt
      721 tcattagcga ctcgtgaagc cgttcaattg attgttattg atatgtatgc gccttatgtt
      781 tcgttggtga aaaagctttt cccgaatgct cagttgatca tcgatcgttt ccacatcgtc
      841 caacatattg gcagaacttt cttgaatcat cgagtgaaag aaaccacggt acgacttaaa
      901 ggaaattccc actctcaacg agggttaggg aaaaaattga agcgctattg gaaactccta
      961 caaaaagaag aagcaaagtt aaactatgaa aaacgggttt ggcgtgccag ttttaaagat
     1021 tatttgactg aaagtgagat tgccgatcga ctgttagctg cttgtcccaa cttacgccaa
     1081 ggctatcagt tataccaaga cattctttat gcggtaaaga aaagagatca gtcactattt
     1141 gaggattgtt taactagaga cattagcggt ctgccagaaa cctatacaac cactttacga
     1201 acgtttaaaa agtttctgcc acagatccaa aatgcgcttc actacagcta ttcaaacgga
     1261 ccattggaat gcttaaacaa ccacatcaaa gtattaaaac gcaatgcgta cggctttcgc
     1321 aacttttaca atttcaaact acgaattatg attcgtcatg gcaaaacatt tttaaccaaa
     1381 taaacagaac agaaagaggt tttcttcttt ctgttctgtc c
//
LOCUS       DAIGQM010000150         1389 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.160, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000150 DAIGQM010000000
VERSION     DAIGQM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.160"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            278..820
                     /locus_tag="NOA48_002753"
     CDS             278..820
                     /locus_tag="NOA48_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790949.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..1326
                     /locus_tag="NOA48_002754"
                     /pseudo
     CDS             976..1326
                     /locus_tag="NOA48_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          551 a          164 c          265 g          409 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggct
//
LOCUS       DAIGQM010000151         1353 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.161, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000151 DAIGQM010000000
VERSION     DAIGQM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.161"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..580
                     /locus_tag="NOA48_002755"
     CDS             <1..580
                     /locus_tag="NOA48_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790950.1"
                     /translation="VAALRLIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQ
                     LVSGNFTLKGEGQLTFYLLPTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHY
                     LLASRSYGPYTSELLVSERDSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYRE
                     KANPVLANVLLLDLATLLHANKRPKKIAATKK"
     gene            595..1158
                     /locus_tag="NOA48_002756"
     CDS             595..1158
                     /locus_tag="NOA48_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI0790951.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
BASE COUNT          458 a          227 c          259 g          409 t
ORIGIN      
        1 agtagccgct ttacgtttga tcgatatctt agcagataca tctgaagaga cgggacagcc
       61 aatcgcttat tggctgacaa ctgatctctc agagattcca caagcatcgt atttgactca
      121 aaacaatgat caactggtat ctggcaactt cacactaaaa ggtgaaggac agttgacttt
      181 ctatctattg ccgacgatag ctgaaatgaa aacagcaatt cgccgcaaag acaaaatcca
      241 accaaccgtg acaatgagca gaaaaacatc tgataagatt caaggtgtgg ctttttatgg
      301 ccattatctc ttagccagtc gttcttatgg tccttatacc tcggaactct tagtgtccga
      361 gcgggactct cctagccgga tcctaaaacg aatcaaattt ccaccgtatt tggaacaaat
      421 cgttgttgta gaagatcgtc tagcagtatt gtttgaaagt ggcgccgcag cgtatcgcga
      481 gaaagccaat cctgtgttag ccaatgtttt attactagac ttagcaacgt tgcttcatgc
      541 aaataagcgt cccaaaaaga ttgctgcaac taaaaaatag tcggacaact caagatgatc
      601 actgttgttc ataaagaacg acaagaaaaa tcatctagcg atgttcgact atgggtttat
      661 ttaggaagta tttctactaa gattcaatat ggctatacag attcggcgaa aaaacaaggc
      721 aatgttaagt ttttgagaat cacagatata caagagggac gtgtaaattg gtccagtgtg
      781 ccttactgtg atattagtaa ttctaaacta gttgatttaa gattggaaga aaatgacatt
      841 ttgatagcaa ggacaggagg aactatggga aaaagtttct tggttaagga aataagtgag
      901 gaatctgttt ttgcttctta cttgattcga attaggttag ttgagaaatt attatcagaa
      961 tacgtagact gcttcttaga ctcgccatta tattggaagt tattagaaaa aatttcttac
     1021 ggaactgggc aaccaaatgt aaatggtaca aatttatcta aactacttat accattacca
     1081 cctttagaag aacaacaacg catgactact aaaatagaaa tgataagaag atctattcgt
     1141 agaatcaatt ttgagtaaat ataacggacc tagcatccat tttataccag atgatgctag
     1201 gtctattatt tatattttat ggaatttaat tgatttgttc tagtgtttta atattattac
     1261 gacagtaaaa aaatagtttg attcttctaa catgaatgac catctagaag tggaaatgta
     1321 taaaagattt attttatgaa gttttcctaa tat
//
LOCUS       DAIGQM010000152         1352 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.162, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000152 DAIGQM010000000
VERSION     DAIGQM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.162"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            11..1350
                     /locus_tag="NOA48_002757"
     CDS             join(11..452,452..1350)
                     /locus_tag="NOA48_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCI0790952.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DAIGQM010000153         1350 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.163, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000153 DAIGQM010000000
VERSION     DAIGQM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.163"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            76..>1350
                     /locus_tag="NOA48_002758"
     CDS             76..>1350
                     /locus_tag="NOA48_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCI0790953.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLIN"
BASE COUNT          459 a          261 c          257 g          373 t
ORIGIN      
        1 ggtattaaaa aacatatcgt tctctagtat gattaaatca ccacaaaata aacaactgag
       61 aggacgatac gctatatgaa tgattctatc aaaaaaatgc tgagaataac agagaaagat
      121 ttgatgatta cagaggtctc ttacgagacc cttcagaaga aaaagacgtt ggtcgtcgat
      181 gctgttctct cgcctactcc tcgtgcttgt agaagttgtg gttctactgt ggtagatgga
      241 aacgggaaag caattatagt gaaaaatgga aaaaaggaaa cgattgtccg ttttgaacaa
      301 tacaatcata tgcctttggt tatgcgccta aaaaagcaac gctatacctg taaaaactgt
      361 cgcacccatt ggacggctca aagttatttt gtccaaccca gacattcaat cgcaaatcat
      421 gttagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      481 agctgtcagg tatctttgac caccgttatt cgtacattga aagagtttaa aagctattta
      541 ccaaagcaat ctaagaagat cctccccaga gtattgatgg ttgacgaatt tcgttcgcat
      601 gcttccatag aagataagat gagctttatt tgcgcggatg gcgaaacagg aaaattaata
      661 gatgttttgc ctacgcgtaa attacctcga ttaacaagct atttcttagg ttgtaccaat
      721 ccagaagaag tagaattctt ggtgacagac atgaacgccg cctacttcca gctcaccaaa
      781 cgtgttctgc caaatgcgaa agtcgtgatt gatcggtttc atattgtcaa acacatgaat
      841 caagcgttca atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagc cggacagaaa
      901 agccaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc
      961 aaccattatg aatacaaaac atggaaaagt ttccgagcac caaaataccc atttcttact
     1021 gaagcaatga tgattgatcg attgcttgag ttttctccgc ccctaaagga ggcgtatccc
     1081 ttttttcatg aattagttga agcctttcga gacaaagacc ctgacttatt tttctcctta
     1141 ttggcagaac ttcccgaaac gttagatgac agctttcggg aaaagcttca aaaccttctg
     1201 acctatgaag aaggcatcac caacgcaatg atctatcctt attccaatgg aaaaatagaa
     1261 gcgaagaata cccacataaa gacaatgaaa cgagtatcct acggatttaa atcatttgag
     1321 aacatgagaa ttagaatctt tttgatcaat
//
LOCUS       DAIGQM010000154         1350 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.164, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000154 DAIGQM010000000
VERSION     DAIGQM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.164"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            76..>1350
                     /locus_tag="NOA48_002759"
     CDS             76..>1350
                     /locus_tag="NOA48_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HCI0790954.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLIN"
BASE COUNT          457 a          254 c          259 g          380 t
ORIGIN      
        1 ggtattaaaa aacatatcgt tctctagtat gattaaatca cgacaaaata aacaactgag
       61 aggacgatat gctatatgaa tgattctatc aaaaaaatgc tgcgattaat agagaaagat
      121 ttgatgatta cagaggtctc ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat
      181 gctgttttct cacctgctcc ccatacctgt agaaattgtg gttctactgt ggtagatgga
      241 aacgggaaag taattgtagt gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa
      301 tacaatcaca tgcctttggt tatgcgctta aaaaagcagc gctatacctg taaaaactgt
      361 cgaacccatt ggacggctca aagttatttt gttcaaccca gacattcaat cgcgaatcat
      421 gtcagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      481 aattgtcagg tatctttgac caccgttatt cgtacgttga aagagtttaa aagctactta
      541 ccaaagcaat ctaagaggat tctccccaga gtattgatgg ttgatgaatt tcgttcgcac
      601 gcttccatag aagataaaat gagctttatt tgcgcagatg gcgaaacagg acaattaatt
      661 gatgtcttgc ctacgcgtaa attgcctcga ttaacaagct atttcttagg ctgcgctaat
      721 cctgaagaag taaaattttt agtcacagac atgaacgccg cctacttcca gcttaccaaa
      781 cgtattctgc caaatgcgaa agtagtgatt gatcggtttc atattatcaa acacatgaat
      841 caagccttta atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagt aggacagaaa
      901 agtcaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc
      961 aaccattatg aatacaaaac atggaaaagt tttcgagcac caaaataccc atttcttacg
     1021 gaagcgatga tgattgatcg attgcttggc ttttctacgt ccctgaagga ggcgtatccc
     1081 tattttcatg aattagttga agcctttcga gacaaagacc ctgacttatt tttctcctta
     1141 ttggcagaac ttcccgaaac gttagatgac ggctttcggg aaaagctcca aaaccttctg
     1201 acctatgaag aaggcatcac caacgcgatg atctatcctt acaccaatgg aaaaatagaa
     1261 gcgaagaata cccatataaa gacaatgaaa cgagtatcct acggatttaa atcatttgag
     1321 aacatgagaa ttagaatctt tttgatcaat
//
LOCUS       DAIGQM010000155         1322 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.165, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000155 DAIGQM010000000
VERSION     DAIGQM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.165"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            746..1322
                     /locus_tag="NOA48_002760"
                     /pseudo
     CDS             746..1322
                     /locus_tag="NOA48_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738373.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          464 a          241 c          233 g          384 t
ORIGIN      
        1 cctcagttga acctaatgga aggcgtttgg aagtggctca aggaatcggt catcaacaat
       61 gttttttttg accacgtcca gaaaatcaaa cagtcggtcc gcggtttctt agccgatgta
      121 aacgagcgtc cccttgaggt gattgaccga ctgtgcgtgc ggatgtaaag tatttaattc
      181 aacctatata gcatacaata cctaggctac aaaaattttc tgacaatcag aaaagatgct
      241 atctatgatt gggatgaaac acagaaatta aaagtagtta atgtgattga ctactaagca
      301 tgaagaacca ttaaagcgat caaataataa ctaatgatga gcctagggag aaaagattcc
      361 ctaagctttt tcattaagta caaaaataaa taaccagtgt ttttgaaatt gaacttcaca
      421 caatagaaat accgtcttct aaagtataaa aaacgtttat aaagactatc cgcttattca
      481 ctcattttac agtacttttt ccaacctctt tctagacttc agccagctcc tccgctattc
      541 aagaactgat cgatattcca aagaaaaatt ccactatact tgactctaaa ataaaaaaaa
      601 tgaataaaat agtaaattag aatcattgaa aaatagtctg catcctttag acttaaattg
      661 taagcgaaaa cgtttacgac tatattatat taacaggagg aatatcatga aaaaaaaatc
      721 atcactggtc agtttattaa taggaatggt cgctttagcc atctttttaa tcccgaccaa
      781 agcagcacat gctgacgtca ctgtaacaaa cgattgtacg gacttttcaa gcatccaggc
      841 ttcaattaat gcgaattctt caggacaggg taacaccaat tacttcaata ttgaacctgg
      901 tcaatcagac tcttggagta gactttctcg tactgggttt atcttggcga ttgtccataa
      961 aggaatgcta agaacctatt atacgccaac gagtgcttct tactcttatt aagatggtaa
     1021 actttatcaa aaaaacaatt cagctgaaat cacaccattg aaagccgtag tattctctga
     1081 ggaaaaagct actaaaattg taaatatggt caatctctct gatggtacag ttcaggttgc
     1141 attaagcaaa tggaaaactg gcgggtatgc agattacttt gaactttctc gtccagccgt
     1201 tgagagctgg agcagaaaca atgatccaag aggcttttta gtttcattga gagctaaagg
     1261 cgaaatgaat gaatacatat attatttacc tagcattgaa aatatcggtg gaaattattt
     1321 aa
//
LOCUS       DAIGQM010000156         1252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.166, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000156 DAIGQM010000000
VERSION     DAIGQM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.166"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..>1252)
                     /locus_tag="NOA48_002761"
                     /note="aph(2'')-Ia"
     CDS             complement(<1..>1252)
                     /locus_tag="NOA48_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HCI0790955.1"
                     /translation="TEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEI
                     VYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSG
                     FRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGS
                     GYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDE
                     LSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQ
                     NVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDG
                     NNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQD
                     IVEEYYPIETIVYGIKNIKQEFIEN"
BASE COUNT          415 a          217 c           98 g          522 t
ORIGIN      
        1 cattttcgat aaattcctgt ttaatatttt taattccata aacaatagtt tcaataggat
       61 aatattcttc aactatatct tgatattctt ttgctttctc aatatctata tttccataca
      121 ttcttaatat atcttctcca aaatttgttc ctatttcttc ttcactatct tcaagtaagt
      181 atataaaatc acaatattca tctataattc cagaatctcc aaaatcaatt attccagtta
      241 atctattatt gccatctaac aatagatgat tacaactaaa atcattatgg cataaacact
      301 ttttaccctc aaaaactgtt gttgcattta gtctttccat aaaactttct atataatctt
      361 tttctatatc agttaaatca ttataaatag tttcacgcaa caatatatac tcttctaata
      421 cattttgttt attatcaata gtacattcac taatatctgt ataatctaaa ccgtgcattt
      481 gtcttaaaaa actggcaata tctcgtttta acaaattttg ttcttcttct gacatagtag
      541 aataaatttc tggtgttaaa aaagttcctt taatttcttt ataacctagt atagataatt
      601 catcactaat atacgaatat tcaatattag gaatttttac attagtttct aaatttgtat
      661 ttaaaaaatt atatattgct ttttcttttg cataaccttt tttcttatta gtactaaatt
      721 ttgttttaaa aatgtattca ttattaacta aatatgccac actatcataa ccactaccga
      781 ttatttcaat actatctact ttgaaattat caaagtaatg ctcaattaaa tatttcattg
      841 ccttaacatt tgtggcatta tcatcatatc tatattccat taaataacaa tcttcttttt
      901 tgccctcgtg taattcatgt tctggcaaat cttcaataat tctaaaacca gatttttggt
      961 atgcccttat tgctcttgga ttatttttat gagggtctaa aataactgca ttagcatttc
     1021 tttctttttt caaaaattca aaaatcaatt taatatatct tgtaccaatt cctttactcc
     1081 aataatttgg ctctcctata aattgatcca taccatagac tatctcatca gtttttggat
     1141 aatgataatc agtatataac tcatcataca ttttatatat ttgtccatat ccaataggaa
     1201 cattgttata ttcaataatt actctaaaaa cttcatcttc ccaaggctct gt
//
LOCUS       DAIGQM010000157         1133 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.168, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000157 DAIGQM010000000
VERSION     DAIGQM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.168"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..990)
                     /locus_tag="NOA48_002762"
     CDS             complement(<1..990)
                     /locus_tag="NOA48_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0790956.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETYKRLRIDPKDLERMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQDVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDS"
BASE COUNT          326 a          210 c          143 g          454 t
ORIGIN      
        1 ggaatctaat tccacaaacg gtacatttaa ctcaccagtt ttgtaattta ctccactaat
       61 tagcgacata acttgctctc tttccatatt aaaaaaattt tttatatgtg attcttctaa
      121 attcttttca agttgttcag aaacagattc aaatgaatat cttttcccta actttcttgc
      181 actaaaagta cgttcgacat actgactttt ttcttttcta gattgtttat ctcttcctaa
      241 agtaattaac tcacctctac gctcatagaa atttacatct tgtttgtaaa gaacatagcc
      301 aagtttgtta tttgtttttg aaaattgata aacttcaatg ttatattctt ttgccaaatg
      361 atccgaaaaa tcttcaaaag aattcacttc gcatttttcc aacgttgctt cgatcgcatt
      421 ttgcacaaac tcttgataat taatttttcc atatttcatc ttagaaggat cgtttgaata
      481 aagattggtt ctcttttcta agttttcata gtactcatta ttcactgatt caagaccatg
      541 ttcattgagg acttgatcgt taatttttcg cattcgttct aaatctttag ggtcaatacg
      601 caacctttta tatgtttcca tgttaatatt attaatgaca agatgactat gaaaatgatc
      661 tttatcattg tgacttgcaa caatgatttg cgaatttgga aaagctttct ctgcaaattc
      721 gacagctatt tcgtgcattt tatcaatact taactcttta gaagtactct tatcaaacga
      781 atgaataaca tgaaacgctt gtgctatatc tttagattta ttcatcttgg tacgtactaa
      841 attcatttct tgcagtgctt cctcactatc atcactacaa tttattcctg agactgcaac
      901 acatttttct ttttttgaag gattagctgc atattgtaat agcgaggata aatttttctt
      961 gcgtcctttc gatgttatag tagctcccaa agttgtttca cctcatcttt taaacttgca
     1021 ataatctgaa ttgagtgaat taaattccga tcaacttttt gggaatactc ttctttcgta
     1081 cccggtctag tttgcttttc tatccaatat tcgaaatatt ctttttctac ttc
//
LOCUS       DAIGQM010000158         1090 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.169, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000158 DAIGQM010000000
VERSION     DAIGQM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.169"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            5..979
                     /gene="bsh"
                     /locus_tag="NOA48_002763"
     CDS             5..979
                     /gene="bsh"
                     /locus_tag="NOA48_002763"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI0790957.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          383 a          135 c          187 g          385 t
ORIGIN      
        1 aactatgtgt acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga
       61 ttatgaaata tcttacaatg aagtagttac tgttactcca agaaattata agttgaattt
      121 tcgaaaggta aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc
      181 tgactaccct ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa
      241 tttttctggg tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt
      301 tgaatttatt ccttggattt taggacaatg ctcaacagta ggagaaacta aaaaattgtt
      361 aaaaaatatc aatttagcaa atataaatta tagtgatgaa cttcctttat cccctttaca
      421 ttggctatta gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca
      481 tatatatgat aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt
      541 taatttaaac aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca
      601 aataagtttg aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc
      661 ctcagtatct cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc
      721 agagtcagaa agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg
      781 tttgtgtgat gttggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt
      841 tgacaaagga atctattatt atcgaacata tgaagacagt caaattactg caattgatat
      901 gaataaagaa gacttagata gtcataagtt aattagttat ccaattatag aaaaacaaca
      961 aattaaatat ataaattagt taatgtgttg tgattgatta tttaatatag atataataca
     1021 aaaaggcaaa gatattttca aaacattttt tcttgatgtg atatccttgt cttttttgta
     1081 atgtttttaa
//
LOCUS       DAIGQM010000159         1062 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.170, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000159 DAIGQM010000000
VERSION     DAIGQM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.170"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(37..993)
                     /locus_tag="NOA48_002764"
     CDS             complement(37..993)
                     /locus_tag="NOA48_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790958.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAIGQM010000160         1050 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.171, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000160 DAIGQM010000000
VERSION     DAIGQM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.171"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            89..1024
                     /locus_tag="NOA48_002765"
     CDS             89..1024
                     /locus_tag="NOA48_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0790959.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYTGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          366 a          167 c          238 g          279 t
ORIGIN      
        1 gttataaaaa tgaacattgc atagtagaga ttctttgatt atactaattc aaggttatat
       61 gaaaaaagag aaatgagatg gatgatttat gaaactttgg atgaaaatcc ttttaggcgt
      121 cgctttagct ctgattgttg cgttagtgtt tgcagggaat tatttttata attatgctgt
      181 tgtgccttct gagaaagact ttttagacga agatacacct ggtacaacac agacatccaa
      241 agaaacggat gcacataaat ggtttagttc aaaagaaaac cgaagcgatt ggaccatcac
      301 ttcaaaagac ggtctgaaat tatcagcgat ttatcttcct gctgaaacga aaagtgaaaa
      361 aacagctctt gtggctcatg gctatatggg aaacgctgaa acgatgacca attacgcaaa
      421 gatgtttcat gatatgggtt acaatgtcct tgttcctgat gcaagaggac atggaaaaag
      481 cgaaggggat tacactggat ttggatggcc agagcgtaaa gactatgtac agtggataaa
      541 caaagtgcta gaaaacaatg gaaaatcgca agaaatcgtt ctatacggtg tcagcatggg
      601 agcagcaaca gttatgatga ctagcggaga aaaactacca gataatgtga aagcaatcat
      661 tgaagattgc ggttattctt ccgttcatga tgagcttgct tatcagctag acgatatgtt
      721 tagtcttcca gcatttccgc ttatgcaagt aacgagtcta gtgacaaaag tccgtgctgg
      781 ctactttttc ggtgaagcaa atgcagtgga acaattgaag aaaaaccagc gcccaatgct
      841 ctttatacat ggagacgaag atacatttgt accatttgaa atgttagata aggtctatcg
      901 tgcaacgaag ggaccaaaag aaaagtatgt tgtaaaagga gccgagcatg cggaagcata
      961 caagacagat cctgaaaaat atcagcaagt agtccaacaa tttttaagcc aatatgttca
     1021 ttgaacgagt ttaaaagtag gggatgaaaa
//
LOCUS       DAIGQM010000161         1045 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.172, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000161 DAIGQM010000000
VERSION     DAIGQM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.172"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(150..>1045)
                     /locus_tag="NOA48_002766"
     CDS             complement(150..>1045)
                     /locus_tag="NOA48_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCI0790960.1"
                     /translation="SEKALIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLM
                     KQLDPFVFEWRNRSLEGSEYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTIL
                     GFDVQDGESEDNWDTVFQSFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAH
                     FLRNIFDKLPKKVSSDVKDELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILE
                     NGFEDAIQILSFPENIRRRIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLM
                     EKDTEWLASPRKYLEFNSNNI"
BASE COUNT          315 a          239 c          182 g          309 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttc
//
LOCUS       DAIGQM010000162         1035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.173, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000162 DAIGQM010000000
VERSION     DAIGQM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.173"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..>1035)
                     /locus_tag="NOA48_002767"
     rRNA            complement(<1..>1035)
                     /locus_tag="NOA48_002767"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAIGQM010000163         1031 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.174, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000163 DAIGQM010000000
VERSION     DAIGQM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.174"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..888
                     /locus_tag="NOA48_002768"
     CDS             <1..888
                     /locus_tag="NOA48_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan endopeptidase"
                     /protein_id="HCI0790961.1"
                     /translation="QINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGD
                     GKYLYSIYKDQDSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEK
                     PQIGSVFSARLKLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNN
                     EDFWSSLDVNYSKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFE
                     DTQITMLENKSVKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYEL
                     KKDGRVYGYINSEAAVEMN"
BASE COUNT          394 a          124 c          187 g          326 t
ORIGIN      
        1 caaataaaca gatatttaac ttctaaagat agtggtcaac caacttgggg aaatctagag
       61 tgtactataa gtaaaggaca aactacaaaa gataaaatat attttgttaa aggagcatat
      121 aatttagggg atggaaagta tctatattct atttataaag atcaggattc ctctgaatgg
      181 ttagggtatt taaaagcaca tgttagttta gcctatactc ctattgaaga aattaataaa
      241 aacgtaactg ttactaaaaa ttggtcgatt tggaataatc tacaatggga aaaggaaatt
      301 gaaaagcctc agattggttc tgtattttca gctagattaa agttaaccaa tgtatcgaat
      361 aatgctgtct attacaagct ttataaatct ggaaaatttt atggttatat caatgctgag
      421 gctgtcaaag accttacaac aacaaagctt aataagtatg ttacatttag tgttaataat
      481 gaagattttt ggtcttcttt agatgtaaat tattcaaaag gaaaaactga aagaggccga
      541 gtattttaca ttagtatttc atataatacc gcagataacc aaccgattta ttcagtatat
      601 acagatgaaa catgtacgga atggcgaggg tattataagg gaaacaactt tgaagacact
      661 caaattacta tgcttgagaa taaaagcgtg aaagtaacaa aaagtgggta tacagtatgg
      721 ggagacttga atttttggac taagtcagga atatcgaaca caggagatat atacaccact
      781 gaccgaaaat tttataattt taccaacaat gcttactatt atgaattgaa aaaagatggg
      841 agggtctatg gctatataaa tagtgaagca gctgtagaga tgaactaaaa tattgctgtc
      901 ccttaatctt atggggcagc aatattttta tattattaat catttttctg aagcgagggt
      961 agaagaatta atcaatagtt tttcttgttt tgtaatataa tagtttaatt accaaaaatt
     1021 atttaagtaa a
//
LOCUS       DAIGQM010000164          979 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.175, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000164 DAIGQM010000000
VERSION     DAIGQM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.175"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            108..>979
                     /locus_tag="NOA48_002769"
     CDS             108..>979
                     /locus_tag="NOA48_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCI0790962.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVT"
BASE COUNT          428 a          105 c          158 g          288 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaac
//
LOCUS       DAIGQM010000165          967 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.176, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000165 DAIGQM010000000
VERSION     DAIGQM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.176"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            128..>967
                     /locus_tag="NOA48_002770"
     CDS             128..>967
                     /locus_tag="NOA48_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0790963.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQ"
BASE COUNT          391 a          119 c          161 g          296 t
ORIGIN      
        1 cagtttgtaa caaacatata ttttttatat tacaatattt caacaaatta aaaaaaatta
       61 tatcttctta aacaatgata atattaaaat gcaagcgctt gtaaaaaata aggagaagag
      121 gtaaaaaatg aagaaaaaac tattaacttt atttcttgtg atgtctttct caatcgtttt
      181 gagtgtgtac tacaatacta ttgttttttc agaacaaata aactacacag aagaacagta
      241 taatatagaa aaagaaaaag ctttaaaagt tggttatagt gaagaacagt ttaagcagat
      301 tatggaaata cctacaaatt tatcaaatga aaatagtgaa acaagaatag taaattatac
      361 tatgacttct aatcaaacca aagtcattaa taaagcaatg gagcaaattg gaaagccata
      421 cgaatgggga gcatcgggac caaattcttt tgactgtggt ggtttagtga aatatgttta
      481 caaacaagct gtaaatattg aactgcctat gggaaccacc aatcaagagc aatacggtac
      541 agaggtaagt ttaaattcac ttaagcctgg tgatttatta ttttacggca atcgaggtgc
      601 aacttatcat gtaggtatat ataaaggtaa cggtgtaatg attcatgcac cgcaacctgg
      661 agaaactgta aaagaggtta acatacaata tttttatcct aactttgcaa aaagaatttt
      721 gcctgatgaa cctgactacc cttatattga ctataataaa atggtaactg ttacaaaagc
      781 ttggtcaata tggaatgatt tacaatttag tcatgaaatt aagaaagcta ttattggaga
      841 taattacaag atagggaagg tttatactaa tccagaaaat aataataaat atggagaaat
      901 attagtaagt aataaagtat atggatacat taatttttat gctgttaaag agttgacctc
      961 tgttcaa
//
LOCUS       DAIGQM010000166          927 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.177, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000166 DAIGQM010000000
VERSION     DAIGQM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.177"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            54..927
                     /locus_tag="NOA48_002771"
                     /pseudo
     CDS             54..927
                     /locus_tag="NOA48_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          362 a          153 c          177 g          235 t
ORIGIN      
        1 acagaaaaat taaggtgtgt agactagaag aaaacatacc aggaggaatt tttatgtcta
       61 agagaacacg aagaactttt tcacaagaat tcaagcaaca aatcgtcaat ctttacttag
      121 ctggaaagcc acgtgtagaa atcattcgag aatatgaact aacggcttca gcatttgaca
      181 aatgggtaaa gcaatctaaa acgagtggtt cattcaaaga aaaagataat cttacgcctg
      241 aacaaaaaga attgttagaa ctacgtaaaa gaaaccagca attagaaatg gaaaatgata
      301 ttttaaagca agcagcgctg atattcggac gaagagacaa gtaatcgatg cgaataagca
      361 tctttaccct atatcagcga tgtgcagaat attaggtcta tcacgtcagt cctattatta
      421 tcaatcaaaa ccaaagaaag acgaatcaga acttgaagaa gtagtcgctg aagaatttat
      481 ccgcagccga aaggcctacg gctcaagaaa aataaaaaaa gccttatcaa aacgaggcat
      541 tcagatcagc cgacgaaaaa ttagtagaat catgaaaaat agaggattaa aatcgagcta
      601 tactgttgct tattttaaag tacatcattc tacttgcaat gaagccaaaa cgacaaacgt
      661 attgaatcgt aaattcttaa gagacaaccc attagaagcg atcgtaacag acttgactta
      721 tgtacgagtc gggaaaaaat ggaattatgt ctgtttcatt ttggatctgt tcaatcgaga
      781 aattctcggc tattcttgtg gagaacataa agatgccgtt ctagtaaaaa aagcatttag
      841 ccgtatcaaa caacctctga cagaggttga gatttttcat actgatcgtg gaaaagagtt
      901 tgataaccaa gctattgatg aattatt
//
LOCUS       DAIGQM010000167          868 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.178, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000167 DAIGQM010000000
VERSION     DAIGQM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.178"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            81..>868
                     /locus_tag="NOA48_002772"
     CDS             81..>868
                     /locus_tag="NOA48_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HCI0790964.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT          321 a          160 c          161 g          226 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatctt
//
LOCUS       DAIGQM010000168          834 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.179, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000168 DAIGQM010000000
VERSION     DAIGQM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.179"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            120..>834
                     /locus_tag="NOA48_002773"
     CDS             120..>834
                     /locus_tag="NOA48_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0790965.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLKENIYYHTPNDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRNGKLETAYWGSRSSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLEMQ
                     LRRGKATDWHAMVRESLDSF"
BASE COUNT          279 a          117 c          180 g          258 t
ORIGIN      
        1 acgaatattt ttaggtttct tcaagactag agattttttg gtaatgaatt tttaagagtt
       61 acgtgaactt ttgaaaattc tttccagaag tctctttttt ctttgaggag gaactaaatt
      121 tgagtaaaaa aggcacgatc ataaatgagt gggaaaaatt aacagccccc tctaacaggc
      181 ggttaagtgt tgacgataag gtacaccccc taaaattaag ttggtcaatc gatcgaatta
      241 caatcgtcgg aaaactgaaa gaaaatattt attatcacac tccaaatgat gtgttgattt
      301 tagattttga acagcttatg cgcctaaatg aaggtaacgg ttatttaaga tctgttagta
      361 ataatggttg gcagttgtta gaccaacatg aagagaatat tgcttatatt gaaattttaa
      421 aatggcaaga ggggaaaggg cgtatagact tcaatccgaa taagattagt caattcttag
      481 ctagttccat gaaaaatttt attcatgatt tgtttatcga acctcacttt tcacgtgcag
      541 atattgcttg cgacattatc gatgtacctg atgagtttat tacacaatat cgggtagttg
      601 atccagtttc ttttaagcct atttatggac ggaatggaaa attagagacg gcatattggg
      661 gatctcgctc ttctgaacgt caaattcgga tgtataataa aaaactggaa caagagaaga
      721 aaagaaaaat tgtgccaaaa gaaatcgtga gttggtggcg gttagaaatg cagctaagac
      781 gtggcaaagc aacagattgg catgcgatgg ttcgggaaag tttagatagc tttg
//
LOCUS       DAIGQM010000169          792 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.180, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000169 DAIGQM010000000
VERSION     DAIGQM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.180"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(62..262)
                     /locus_tag="NOA48_002774"
     CDS             complement(62..262)
                     /locus_tag="NOA48_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0790966.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          256 a          133 c          122 g          281 t
ORIGIN      
        1 aattttttcg tacaaaaaaa ccgtcttttc tttcgaaaag acggttaaaa gtcaattttt
       61 attaagcttt aacaatgttt gttgcttgag ggccacgttg accatcttca acatcgtaag
      121 acactgcttg gccttcttct aaagttttga agccgtcacc ttggatagct gaaaaatgtg
      181 caaatacatc atttccatct tcaccagtga taaagccaaa acctttgtct gcgttgaacc
      241 attttactgt accgttattc ataaataaat tcctcctgat acgtatcaat gtacgttttt
      301 tcgttgcaat aaatatttga taggcaaaag gagttttatc tatgtagata tatcgctcaa
      361 attacgtttc aaaatagatt actcatttaa tatatcatgc tttttctaat aacacaagga
      421 taatgcaatg aaatataaaa ttcattgtct tctattgtct tcgaatcgaa gaaaaagttg
      481 aataaccgcg attgattcac tttttgtttt cttgtttatt tgcttttatc tgcaactttt
      541 gactttaaaa tttcttaact atgaaaacct ttcaattggt ggtatactta taaatggaat
      601 ttcgttatca acgcgttcgt tgcctttcag caagtattta aagaaaggag aatggctatg
      661 acattctata acaaagatat acaatatcga gtaaccttgg atacagattt gaatctattt
      721 gtcgtttttg acaaagaaaa taccaatcat gtagcgacag gtgttacgat cgaacaagca
      781 gtgcaagaat ta
//
LOCUS       DAIGQM010000170          791 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.181, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000170 DAIGQM010000000
VERSION     DAIGQM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.181"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..782
                     /locus_tag="NOA48_002775"
     CDS             <1..782
                     /locus_tag="NOA48_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0790967.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAIGQM010000171          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.182, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000171 DAIGQM010000000
VERSION     DAIGQM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.182"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            123..>790
                     /locus_tag="NOA48_002776"
     CDS             123..>790
                     /locus_tag="NOA48_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790968.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEV"
BASE COUNT          285 a          124 c          143 g          238 t
ORIGIN      
        1 ttttacactc tcataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt
//
LOCUS       DAIGQM010000172          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.183, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000172 DAIGQM010000000
VERSION     DAIGQM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.183"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..506
                     /locus_tag="NOA48_002777"
     CDS             <1..506
                     /locus_tag="NOA48_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790969.1"
                     /translation="LLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGR
                     KEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRR
                     TIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQ
                     DTLESMI"
BASE COUNT          278 a          131 c          115 g          266 t
ORIGIN      
        1 ttttattagt agtgacagac ggattaagct gtattgaaga aagtatccat agtgtgtatc
       61 cgaatgccca atttcaacaa tgttgtgtgc atgtatctag aaatatcgct cataaagttc
      121 gtgttcgagg tcgaaaagaa atttgtgagg atttcaaatt ggtttaccaa gcgaattcaa
      181 aagaagaggc attggatcac atcgacttta tgactaggaa atggaaaaag cagtatccaa
      241 gagtcgtcaa tttactcttg aatcctgccc tattaacctt ttataatttc cctcacgcca
      301 tcagacgaac aatttattcg acgaacctga ttgaaggctt taataagcag ctaaaacgat
      361 atactcgaag aaaagaacaa ttccctaatg aagaatctct agagagattc ttcatttctc
      421 aatttaatca atataaccaa aaatttttag gtagaattca caagggattt aaagaaattc
      481 aggatacatt agagtcgatg atttaactgt aattaacaga atggattttc catttacata
      541 taattcttga cgctaccata atctaaataa ccatcatatt catctactac ttatataatt
      601 gagttttatt aaacttttta agtttctatt ctatcaaata tttaaacaat ctctgcatcc
      661 gaaaagacta cctcgtatag ttttactaac aatattttta ttagcgtgtt caaatcctga
      721 tttcttgtat caattatttt ctgttcactt tcaataagaa aaaagtcttt acttccatgg
      781 ataataataa
//
LOCUS       DAIGQM010000173          731 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.184, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000173 DAIGQM010000000
VERSION     DAIGQM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.184"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOA48_002778"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOA48_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCI0790970.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="NOA48_002779"
     CDS             complement(481..675)
                     /locus_tag="NOA48_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790971.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DAIGQM010000174          727 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.185, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000174 DAIGQM010000000
VERSION     DAIGQM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.185"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            19..>727
                     /locus_tag="NOA48_002780"
     CDS             19..>727
                     /locus_tag="NOA48_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0790972.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          255 a          126 c          138 g          208 t
ORIGIN      
        1 tataaggagt gagtacaaat gacctatacc catcttacaa cggatgaact tgtaataata
       61 gagtcttatt tcaaaatgaa tcaatctgtt gctaaaactg cccattgctt gaatcgttca
      121 agacaaacga tccataaagt atatctgttc ttcaagcaag gaaaatcagc cttagaatat
      181 tatcaacagt ataagaaaaa caaatcaaac tgtggtagac gtccgcttgt tttacccgag
      241 gaacaatcag aatatattca aagaaaggtt gttcaaggat ggacacccga tgtgattgtt
      301 ggtcgtgcag cgtttcctat tagttgttct gctcgtacca tttatcgtat gttcaaaaag
      361 gggctatttg attcttctga cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa
      421 gaaagacgtg gaaaacaaac tttccgccgc tctattcatg aacgtgaaaa ggattatagc
      481 caattctcaa atgagtttgg tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa
      541 agtgctgtaa ttaccttagt tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt
      601 ggtagacaag cgattgatat tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa
      661 aacctattca aatccatcac ttttgattgt ggaaaggaat tttcaaattg gaaacagatc
      721 agtaatg
//
LOCUS       DAIGQM010000175          697 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.186, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000175 DAIGQM010000000
VERSION     DAIGQM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.186"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(54..629)
                     /locus_tag="NOA48_002781"
     CDS             complement(54..629)
                     /locus_tag="NOA48_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0790973.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          230 a          151 c          125 g          191 t
ORIGIN      
        1 aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt tattcagcct
       61 atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa tgaaacaacg
      121 acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat cacacttgtt
      181 gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc tgaggaggtg
      241 atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg taccgacaaa
      301 atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata tcttggcaaa
      361 atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag agaaaaaata
      421 tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc aggtacaggc
      481 ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg caaacgaagc
      541 cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat cactgtaagt
      601 acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc tttccaaatc
      661 tttcataatc gtttcttctt gtgcatttaa aagaacg
//
LOCUS       DAIGQM010000176          693 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.187, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000176 DAIGQM010000000
VERSION     DAIGQM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.187"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(158..652)
                     /locus_tag="NOA48_002782"
     CDS             complement(158..652)
                     /locus_tag="NOA48_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790974.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
BASE COUNT          215 a          137 c           78 g          263 t
ORIGIN      
        1 ttgaataaaa aaatcaagaa aaagttgctc aaactcttcc ttatttatca ctaatgtttc
       61 aaacggaaca actttatttt cctcagccat tctcccagtt ccattttcaa aaatcacaaa
      121 actgatatta ccttaaaaac tactaacaaa ataaaactta taaagtaaat ggcaacccaa
      181 ctatgtaacc attctctcta cgtactacga tttggtagtc ctgcctttca atcggtaatt
      241 cataatagta atttactgtt tcttctttgc cactttcaat atactctgga ttatccaata
      301 tcatatcata ctcataaagt tcttcaccat ccttattttc aatcgaccat tgttgtggac
      361 gtatcggatt ttctgtatca tttataagtg tataggtcac ttgtaataca cgatcatgtt
      421 gtgcaaattc atttcttttt tcggtcactt caatattttt aaatgttagt tcaaccccat
      481 ctgcctgata agtttcacct atttttaaat cttttgttac aatttttatt ggcttttctt
      541 ctggaaaatg tctggcttta attgttagat aacttccaaa aagaatcaat cctagtagca
      601 ctaaaagaat tcctttaacg agccactgaa acgggaagta aactttaaac atcttttttc
      661 tcctccgttt tttatttgtt ttttagagaa tac
//
LOCUS       DAIGQM010000177          685 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.188, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000177 DAIGQM010000000
VERSION     DAIGQM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.188"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            42..>685
                     /locus_tag="NOA48_002783"
     CDS             42..>685
                     /locus_tag="NOA48_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001878362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HCI0790975.1"
                     /translation="MCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRR
                     FQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRL
                     AYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKL
                     NSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQY"
BASE COUNT          250 a          106 c          145 g          184 t
ORIGIN      
        1 tggaaattat aatcaaacag aaagtagagc tgcaccctaa tatgtgtgtg atgagctgta
       61 cggaacctga gcaatgggat gtggtaatag aaggaaatga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattagaac tcgaacaaga ggaaatcaga agatttcaga
      181 attgctcctt gtaccctgtt tatcatggaa gcgcaaaaag caacataggg attgagcagc
      241 ttatagaagt gataacgaat aaattttatt catcaacata cagaaagaag tctgaacttt
      301 gcggaaatgt cttcaaaatt gaatattcgg aagaaagaca acgtcttgca tatgtacgcc
      361 tttatggcgg aatcctgcat ttgcgggatt cggttagaat atcggaaaag gaaaaaataa
      421 aaattacaga aatgtatact tcaataaatg gtgaattatg taaaattgat aaggcttatt
      481 ccggggaaat tgttattttg caaaatgagt ttttgaagct aaatagtgtt cttggagata
      541 caaagctatt gccacagaga gagagaattg aaaatccgct ccctctgctg caaacaactg
      601 ttgaaccgag caaacctcaa caaagggaaa tgttacttga tgcactttta gaaatctccg
      661 acagtgaccc gcttctacaa tatta
//
LOCUS       DAIGQM010000178          683 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.189, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000178 DAIGQM010000000
VERSION     DAIGQM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.189"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            83..683
                     /locus_tag="NOA48_002784"
                     /pseudo
     CDS             83..683
                     /locus_tag="NOA48_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          259 a          117 c          114 g          193 t
ORIGIN      
        1 tccatgttcc ccactcctca agtgttttct ttagtatacg cctataggag gaaaaacgaa
       61 tacaatttaa ctcaatttat ataataggaa aaatttagcc gaatctgaag gaattagtag
      121 agttactcta tatcaatgga aaaacacggt tcttggaaag gattttccat tgcgtatgac
      181 tttaaaaaat caggaaaaac aaaaagagct acttttaaag gaagtagaag acttacaaaa
      241 acaagtacac caattacagc tcgaaaaagc attactcgaa ggagcggctg aactgctaaa
      301 aaaagaaaaa ggcgtcaatc ttctttgtct atcaaatcaa gaaaaaacga tattgattga
      361 tgccttacga aatcagttca ccttgaaaga gcttcttcaa cagctccagt tgcctaaaag
      421 cagctatttt tatcaaaaac aagcacttga gaaaccagat aagtattaca aagaacgtca
      481 attaattatc acgattttca atcataactt ctgtgcgtat ggttaccgta gaattgacca
      541 agctttaaaa aatatgggta aaaagctttc tgaaaaagtt gtacgtagat tgatgactga
      601 ggaaaatcta tttgttaaat tttctagacg aaaaaagtat tcttcgtatg ctggggaaat
      661 ttctcctgca caccccaatt tat
//
LOCUS       DAIGQM010000179          678 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.190, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000179 DAIGQM010000000
VERSION     DAIGQM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.190"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
BASE COUNT          240 a          113 c           80 g          245 t
ORIGIN      
        1 caaattactt catcaaaaca ttgatataat ttttattata tcagtattta ttcttgatac
       61 ataaatgaga aaataaatac tttaaatcta ttgactacaa gtagtcatta agtcttcata
      121 agatgtacaa tatgacatta aaaaaataaa agcttacgac catccgttaa atctgacact
      181 aaataatgga ctgctttctt ttgtattagc aggttacgtt gactatgaat attcaccaga
      241 ttatttggag aaacctcttc aacacgagaa caatgatatt aattttagat ttgtctacga
      301 gtcaaaaagt aaaacatggt tagttgatca attaagcacg ataaacacaa gcttccatga
      361 attacctaaa cctgaaaatg aagttgagat ggtcattaaa atcttctaaa aaagaagcgt
      421 tgaaggggaa atattccttt caacgctctt ttttatatgc ttagaaacat aaataaattg
      481 tatactttct ttttagcccc tattactttt cacgaaaaat atcttttttt cgacgctagc
      541 gtttctctac ttctaatact gtacacagtt tttgtattat tgaaaaatta ctcattattt
      601 agcattaatc cacatcgttt tatcaatcga ccttcatact aaactacttt aaagtcatct
      661 tccttctcgt ttttcatt
//
LOCUS       DAIGQM010000180          637 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.191, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000180 DAIGQM010000000
VERSION     DAIGQM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.191"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            51..>637
                     /locus_tag="NOA48_002785"
     CDS             51..>637
                     /locus_tag="NOA48_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCI0790976.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEA"
BASE COUNT          231 a          106 c          126 g          174 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccat
//
LOCUS       DAIGQM010000181          622 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.192, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000181 DAIGQM010000000
VERSION     DAIGQM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.192"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            101..>622
                     /locus_tag="NOA48_002786"
     CDS             101..>622
                     /locus_tag="NOA48_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790977.1"
                     /translation="MISDNKWEINLKRFISEYIYTIETKSSFSLNEDSDPLKKYTIQC
                     KKNKDEKLFVIRPDLMKSNTHYIKEKPKDCDYIIISEANKTVFLIELKSSAQTSPAKE
                     ISEQIDGGYKWLQHLSFLTKYDFTEFSYKIIKVCCKFEARQDRKNLFKPNEYGIYNMN
                     GPKLDLRELYRKCN"
BASE COUNT          263 a           68 c           98 g          193 t
ORIGIN      
        1 aaatttctaa catcagttat tatgataatt ttgatgatgt caattatgat ttacaggaaa
       61 gatataatga tttaatcgaa gaattagagg agagaggaga atgatttcag ataataaatg
      121 ggaaataaat ctcaaaagat ttatttcaga atatatatat acgattgaaa ctaaatctag
      181 tttttctctt aatgaagaca gtgatcctct aaaaaaatac actattcaat gtaagaaaaa
      241 taaagatgaa aaattgttcg taataagacc agatcttatg aagagtaata cccactatat
      301 aaaagaaaaa cctaaagatt gtgactacat catcataagt gaagcaaata aaacagtatt
      361 tctgatagaa cttaaaagct cagctcagac ttcccctgca aaagaaatta gtgaacaaat
      421 tgatggtgga tataagtggt tacaacatct tagttttcta acaaaatatg attttactga
      481 attcagttat aaaattatta aggtatgttg taaatttgag gcaagacaag atcgtaaaaa
      541 tctttttaaa cctaatgaat atggtattta taatatgaat ggtccaaaat tagacttaag
      601 agagttgtat agaaagtgta ac
//
LOCUS       DAIGQM010000182          600 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.193, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000182 DAIGQM010000000
VERSION     DAIGQM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.193"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
BASE COUNT          258 a           70 c           79 g          193 t
ORIGIN      
        1 tatactttat ttcaaccgaa aatactatta aaacaataac tgaagattta gagaattagt
       61 agtcgatttc gagttatata ttgtaaaaga aaaaatcggt tataaaataa ctaataaagc
      121 atatttttga ttctttacaa gaaaaactaa aatcatcaag aatatataat tatttgtgtg
      181 aatctaattg aatggaagtt ttatgctact taactacaag caatcttagc tgtttggtcg
      241 ttaaaaataa cttaaatagg cgaagtcctt caaaaccaac agtatttcac ataaagattg
      301 taactcgtga aaagtattac acattaagat aaatactaat ctgtttgctt caaattgctg
      361 attaaaaagt aaagtaatta tagaaggaaa tattatataa aggagatttt atcttgatac
      421 ataatgaaga tagtagagta aaagtaccag cgctattaca tttcaaaaga ttgggctatg
      481 agtaccaaac taaaaaaatc aaaaaattga tagtcgaaat aatatttttg tagacatttt
      541 taccagttca atcaataaaa ttaataactc aaactttacc gaagagaaaa tacaattatt
//
LOCUS       DAIGQM010000183          588 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.194, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000183 DAIGQM010000000
VERSION     DAIGQM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.194"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..489
                     /locus_tag="NOA48_002787"
     CDS             <1..489
                     /locus_tag="NOA48_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790978.1"
                     /translation="LSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLN
                     KLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIK
                     VDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMG
                     LA"
BASE COUNT          212 a           91 c          114 g          171 t
ORIGIN      
        1 ttgtctaggc gtgctttatt ggctaaaaat aaaggtacca atctatttga agctaaaaat
       61 tatcaaaaac aaaaacgcaa agtagctaga ttgcatgaaa aagtaatgaa tcaacgtact
      121 gattttctga ataagttgag tacagaaatg atcaaaaatc acgatattat ctgtattgaa
      181 gacttaaaca caaaaggtat gttgcgaaat cataaattag ctaaaagtat ttctgatgtt
      241 tcttggtcaa agtttgtgac taaattacaa tacaaggctg actggtatgg acgaaaaatc
      301 atcaaagtag ataaatggtt tccgtctagt cagatttgtt cagagtgcgg acataaagat
      361 ggcaagaaat ctcttgaaat tcgagaatgg acttgtcctg tttgtcatac tcatcatgat
      421 cgtgatatca atgctagtat caatattctg accgaaggtc taagactaca ttctatggga
      481 ttggcttaga tccaatcatc aagaaccgta ggaactacgg ggatagcttg gtaaataaga
      541 gacaccgctg ttagtaaaga aatacgctat caagtatgct ctattccc
//
LOCUS       DAIGQM010000184          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.195, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000184 DAIGQM010000000
VERSION     DAIGQM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.195"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>583
                     /locus_tag="NOA48_002788"
     rRNA            <1..>583
                     /locus_tag="NOA48_002788"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          174 a          126 c          167 g          116 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc gga
//
LOCUS       DAIGQM010000185          579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.196, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000185 DAIGQM010000000
VERSION     DAIGQM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.196"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>579
                     /locus_tag="NOA48_002789"
     rRNA            <1..>579
                     /locus_tag="NOA48_002789"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          114 c          173 g          120 t
ORIGIN      
        1 aaagcacccc ggaaggggag tgaaatagaa cctgaaaccg tgtgcctaca acaagtcaaa
       61 gcccgttaat gggtgatggc gtgccttttg tagaatgaac cggcgagtta cgattgcatg
      121 cgaggttaag ttgaagagac ggagccgcag cgaaagcgag tctgaatagg gcgtttgagt
      181 atgtagtcgt agacccgaaa ccatgtgatc tacccatgtc caggttgaag gtgcggtaaa
      241 acgcactgga ggaccgaacc cacgtacgtt gaaaagtgcg gggatgaggt gtgggtagcg
      301 gagaaattcc aaacgaactt ggagatagct ggttctctcc gaaatagctt tagggctagc
      361 ctcggaattg agaatgatgg aggtagagca ctgtttggac taggggccca tctcgggtta
      421 ccgaattcag ataaactccg aatgccattc attcatatcc gggagtcaga ctgtgagtga
      481 taagatccat agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaatatatg
      541 ttaagtggaa aaggatgtgg ggttgcacag acaactagg
//
LOCUS       DAIGQM010000186          568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.197, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000186 DAIGQM010000000
VERSION     DAIGQM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.197"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>568
                     /locus_tag="NOA48_002790"
     CDS             <1..>568
                     /locus_tag="NOA48_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0790979.1"
                     /translation="KGKGRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVRE
                     IRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKL
                     AKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYK
                     EVPKHQHKRALVLTARKFTRLVDTLLRKH"
BASE COUNT          212 a          109 c          103 g          144 t
ORIGIN      
        1 aaaggaaaag gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt
       61 accatgagtt accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt
      121 ctcgtacgag aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa
      181 caagtaattg ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa
      241 gtctatgctg ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca
      301 aaattggcaa aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg
      361 caaaatacac ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct
      421 gccaactctg taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag
      481 gaggttccaa agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt
      541 ctggtggata cgctactacg taaacacc
//
LOCUS       DAIGQM010000187          567 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.198, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000187 DAIGQM010000000
VERSION     DAIGQM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.198"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            141..398
                     /locus_tag="NOA48_002791"
     CDS             141..398
                     /locus_tag="NOA48_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790980.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          239 a           69 c           80 g          179 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtc
//
LOCUS       DAIGQM010000188          563 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.199, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000188 DAIGQM010000000
VERSION     DAIGQM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.199"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(5..436)
                     /locus_tag="NOA48_002792"
     CDS             complement(5..436)
                     /locus_tag="NOA48_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCI0790981.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          196 a           73 c           65 g          229 t
ORIGIN      
        1 atttttagtt attaacttga ttaaaatcag agataatatc atttaattca gtttgaaggg
       61 ttgtaacgat taaatggaaa ttttcttcat ctgttttatt atatggggat gttttcgtta
      121 tatataacaa cttttctttt tcaattttca ttaataactc tgtcgaagtc tgtactttat
      181 cttgataatt aaatgcagac ataccacttt gtataattgt aattattgct gaagcaattg
      241 aaacaatcaa tagtaaagac ctgtgttcgg aagcctgatc aattaatatt gggatactag
      301 ctgataagac tatttttata atatttccga taccaattac tctattataa aatcgaattt
      361 ctttttttaa tctatcgatt gtagaatcaa tagattcgat aaacgctttt tgatccatca
      421 ttttctctcc aatcatttta ttaaaatcat taacaaaaat attataatag gatttaagta
      481 agttctaact aatcacatat aaaaataaaa aaacatttgt attttatcaa agttttatta
      541 tacttgtcaa tttgtgtaca tcc
//
LOCUS       DAIGQM010000189          561 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.200, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000189 DAIGQM010000000
VERSION     DAIGQM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.200"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..528
                     /locus_tag="NOA48_002793"
     CDS             <1..528
                     /locus_tag="NOA48_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790982.1"
                     /translation="RTFRNHRIKETNQLLKSKEQKHYQLGKQLKRYWKLLQKDERKLD
                     YTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFLYAVKERDYVSFEELLTN
                     NIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHIKVLKRNAYGFRSFYNF
                     KLRIMIRHGNALIFN"
BASE COUNT          198 a          117 c           96 g          150 t
ORIGIN      
        1 cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac tattaaaaag caaagaacaa
       61 aaacactatc aattaggtaa gcaattaaaa agatactgga aacttcttca aaaagatgaa
      121 cgcaagcttg attatactcg acgcctttgg cgacctggct tcaaagctca tttaacagag
      181 accgatattg tggatcgctt actgaaaggg agccctgctt tgcgtgtagg ctatcagtta
      241 tatcaagact ttctttacgc tgtaaaggaa cgagactacg tatcgtttga agaactactt
      301 accaataata tcatgcttcc cgaaggctat cagacgacct tgagaacgtt ccagaaattt
      361 ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa atggcccact tgaatgtctg
      421 aacaaccata tcaaagtgtt aaaacgaaat gcatatggct ttcgtagctt ttataatttc
      481 aaattgcgca tcatgattcg tcatggcaac gcattgattt tcaactaaaa aagatcaaga
      541 ggaactgatc cacttgatct c
//
LOCUS       DAIGQM010000190          540 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.201, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000190 DAIGQM010000000
VERSION     DAIGQM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.201"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            1..540
                     /locus_tag="NOA48_002794"
                     /pseudo
     CDS             1..540
                     /locus_tag="NOA48_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          152 a          136 c          133 g          119 t
ORIGIN      
        1 gtgccaattg gacattggcg attgtgtgtg acctgattct ccgggaatgg agttatggat
       61 atacgcaaaa aggcgtggcg gacctccttc accggctagg actaagctgg acccgtccga
      121 cgtataccct caaaaaagcg gattccaaga aacaacaggt atttttggaa gaaaccttcc
      181 cgagcctaaa aaaaaattgc tgaatagcga tattgaccac ctcctattcg aggacgaaac
      241 catgatccgg gattaccaag ccattggctg cacctggttt ctccgcggcc accagcgaaa
      301 aatccccact tatggacaac acaaaggggt aaaattgata ggcaccttgg attatgaaac
      361 cggtcggatc atttgtacag aagaaggggc atacgacgca gcggccttcc tccgttttct
      421 ggagcggacg ttgcgggaat accccaccgg aaaaatcgtg atggtattgg ataatgccct
      481 tatccaccac gccaagctga tccagtcttt tcttgaagaa aacgctaggc gcctggcact
//
LOCUS       DAIGQM010000191          528 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.202, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000191 DAIGQM010000000
VERSION     DAIGQM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.202"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(5..90)
                     /locus_tag="NOA48_002795"
     tRNA            complement(5..90)
                     /locus_tag="NOA48_002795"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="NOA48_002796"
     tRNA            complement(107..178)
                     /locus_tag="NOA48_002796"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="NOA48_002797"
     tRNA            complement(190..262)
                     /locus_tag="NOA48_002797"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="NOA48_002798"
     tRNA            complement(280..361)
                     /locus_tag="NOA48_002798"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="NOA48_002799"
     tRNA            complement(369..441)
                     /locus_tag="NOA48_002799"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="NOA48_002800"
     tRNA            complement(445..517)
                     /locus_tag="NOA48_002800"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAIGQM010000192          526 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.203, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000192 DAIGQM010000000
VERSION     DAIGQM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.203"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            6..398
                     /locus_tag="NOA48_002801"
     CDS             6..398
                     /locus_tag="NOA48_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0790983.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          208 a           35 c           92 g          191 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat ggtggtagag ataaaaaata tacatt
//
LOCUS       DAIGQM010000193          510 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.204, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000193 DAIGQM010000000
VERSION     DAIGQM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.204"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..434)
                     /locus_tag="NOA48_002802"
     CDS             complement(<1..434)
                     /locus_tag="NOA48_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0790984.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
BASE COUNT          146 a           85 c           80 g          199 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc
//
LOCUS       DAIGQM010000194          508 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.205, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000194 DAIGQM010000000
VERSION     DAIGQM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.205"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(77..149)
                     /locus_tag="NOA48_002803"
     tRNA            complement(77..149)
                     /locus_tag="NOA48_002803"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
BASE COUNT          162 a          112 c           83 g          151 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaa
//
LOCUS       DAIGQM010000195          486 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.206, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000195 DAIGQM010000000
VERSION     DAIGQM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.206"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..>486)
                     /locus_tag="NOA48_002804"
     CDS             complement(<1..>486)
                     /locus_tag="NOA48_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790985.1"
                     /translation="LYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLN
                     QCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMR
                     WTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTS
                     L"
BASE COUNT          127 a          107 c           84 g          168 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc ggacaaatat aacaatcaaa atactcgtca
      481 tagaga
//
LOCUS       DAIGQM010000196          484 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.207, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000196 DAIGQM010000000
VERSION     DAIGQM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.207"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(126..>484)
                     /locus_tag="NOA48_002805"
     CDS             complement(126..>484)
                     /locus_tag="NOA48_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HCI0790986.1"
                     /translation="IKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKS
                     KTISIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQ
                     MIENQQKRQQNFEMEF"
BASE COUNT          138 a           89 c           86 g          171 t
ORIGIN      
        1 agcctagcgt gagcggggcg gattgactgg caagtagatg ggtagctggc gtatgtccta
       61 aaaactgctt ctttccaagc aactcttcat aggcaaaaaa ctggaaagtc cactaacaag
      121 cccattcaga attccatttc aaaattttgt tgcctttttt gctgattttc aatcatttgt
      181 tgtgtgaatt cataatcctt tttagcacga tacattttta catcgtcatt cattatgcga
      241 ctgatttgat agtgaatctg tttagcagaa ggtgtatgag aacaattttc aaaacccttt
      301 gccggtagaa ataactcttt ctgatcagtc tttttaatag aaattgtttt acttttcgca
      361 ctacgtaaag tttgaggatt cacatccgta tgaagtttaa tcgtgtattc ttgatcatct
      421 tctaaagaca ttgtatttac aaaatgcttg tctacctctc gcaagaagtc atcatattta
      481 atga
//
LOCUS       DAIGQM010000197          479 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.208, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000197 DAIGQM010000000
VERSION     DAIGQM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.208"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            136..>479
                     /locus_tag="NOA48_002806"
     CDS             136..>479
                     /locus_tag="NOA48_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790987.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          214 a           65 c           69 g          131 t
ORIGIN      
        1 aacatttaca aaattagcta aagctgaaca atatagacga tctttagaat tgtcaaaaga
       61 ttaaatatat aaaaagcctt cgggcttttt cttttaacaa ttaataggaa cgtatattcg
      121 aaaggaatag aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa
      181 cgttatacgg atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat
      241 tcacgccaag cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata
      301 aaacgaaatg aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa
      361 tacaagccaa ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcattaatt
      421 tcaaaatata taaaagatga tgtacttgta aaaaacgtta atagtaatct tatacaaga
//
LOCUS       DAIGQM010000198          463 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.209, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000198 DAIGQM010000000
VERSION     DAIGQM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.209"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(156..404)
                     /locus_tag="NOA48_002807"
     CDS             complement(156..404)
                     /locus_tag="NOA48_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0790988.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
BASE COUNT          157 a          101 c           68 g          137 t
ORIGIN      
        1 tattttttaa tctgacaaag gtaatgcttg cattcggcga catcagttag acaacatcga
       61 tgatcagtga tagaagcagt ttatctatac aaaaaaagaa gcagcgaaaa tctgctcctt
      121 aagataatag gtaaaattgc tgatatattt gacgattaac ctcttgaacg tcccaagaaa
      181 aatgatacta cagcaacaac gatgatcgca ccaatgatag aaggaatcaa agccattcct
      241 gctaattgag gaccccagct acctaacaat gcttgtccaa ttgctgaacc aactaaacct
      301 gcaacgatgt tagctatcca tcccattgat ccacctttat ttgtaattgc tccggcaatc
      361 aaaccgataa tagctcctac gattaatacc cataaccaat gcataatttt ctctttcttt
      421 ctgtgaaata tttattacac atattatgtt acgcttcttc tta
//
LOCUS       DAIGQM010000199          460 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.210, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000199 DAIGQM010000000
VERSION     DAIGQM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.210"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(20..91)
                     /locus_tag="NOA48_002808"
     tRNA            complement(20..91)
                     /locus_tag="NOA48_002808"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="NOA48_002809"
     tRNA            complement(113..200)
                     /locus_tag="NOA48_002809"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="NOA48_002810"
     tRNA            complement(225..298)
                     /locus_tag="NOA48_002810"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="NOA48_002811"
     tRNA            complement(312..382)
                     /locus_tag="NOA48_002811"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="NOA48_002812"
     tRNA            complement(384..459)
                     /locus_tag="NOA48_002812"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAIGQM010000200          456 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.211, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000200 DAIGQM010000000
VERSION     DAIGQM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.211"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..426)
                     /locus_tag="NOA48_002813"
     CDS             complement(<1..426)
                     /locus_tag="NOA48_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0790989.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQ"
BASE COUNT          132 a           96 c           68 g          160 t
ORIGIN      
        1 ctgataaacc gttgataaat caattccatt ttggtcaatc ttattgataa aaaagattgt
       61 gggaatcccc attttcctaa gtgcatgaaa taatatacga gtttgtgctt gtacgccatc
      121 ttttgcagaa atcagtagaa ttgccccatc taaaactgat aatgaacgat atacttctgc
      181 taagaaatcc atatgtcctg gcgtgtctat gatgttcacc ttcgtatttt cccactgaaa
      241 agaggttatt cctgtctgaa ttgtaattcc tctctgacgt tctaaaagcg tattatccgt
      301 cctcgttgta cctttgtcca cgcttcctaa ttctgtaatc gctccactgt tatataataa
      361 gctttctgtt aaggtagttt ttcctgcatc aacatgagct aaaactccaa tattaataat
      421 tttcatgtga ttttcctcca ttcaaaaacc caaaag
//
LOCUS       DAIGQM010000201          450 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.212, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000201 DAIGQM010000000
VERSION     DAIGQM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.212"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
BASE COUNT          143 a           90 c           67 g          150 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttatat
//
LOCUS       DAIGQM010000202          442 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.213, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000202 DAIGQM010000000
VERSION     DAIGQM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.213"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>442
                     /locus_tag="NOA48_002814"
     rRNA            <1..>442
                     /locus_tag="NOA48_002814"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          100 a          112 c          142 g           88 t
ORIGIN      
        1 ttatggccac tctaacccgc accactaatc gtggtgggag acagtgtcag atgggcagtt
       61 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
      121 ttggaaatca ttcgaagagt gtaaaggcag aagggagctt gactgcgaga ccaacaagtc
      181 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gcatggaagg gccatcgctc
      241 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtc cacatcgacg
      301 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
      361 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
      421 tcggtcccta tccgtcgcgg gc
//
LOCUS       DAIGQM010000203          427 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.214, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000203 DAIGQM010000000
VERSION     DAIGQM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.214"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..>427)
                     /locus_tag="NOA48_002815"
     CDS             complement(<1..>427)
                     /locus_tag="NOA48_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790990.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDEL"
BASE COUNT          125 a           76 c           87 g          139 t
ORIGIN      
        1 agttcatcca atgtgaaatc ttccgtcatg agtgaaatga gggttgcact aaaaagactc
       61 gtcgattcgt ctcgcatttc tcgagcaagc gtattacatt tgtacgttag attttcaaga
      121 aaatgttgct ttgtacgaat caattgctta ataagttgat agcgagtacg tgttaaacgc
      181 tgtaaggcca tgtatttctc ttctttgata ggggaagttg tgaatcgttg aatacgcaag
      241 aaatcagcga ttcttaatgc atcgtttcga tcagttttat tctcatcaaa catgcgacta
      301 aattgtttca cccgaaaagg attttcaatc gttacaagtg tgttgagctt ctttagtttc
      361 tcatcttcat gaaaaaacat ggaaggatgg aagctgtaca tggacgttga ctccatgcca
      421 atcacaa
//
LOCUS       DAIGQM010000204          413 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.215, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000204 DAIGQM010000000
VERSION     DAIGQM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.215"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            91..>413
                     /locus_tag="NOA48_002816"
     CDS             91..>413
                     /locus_tag="NOA48_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCI0790991.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKK"
BASE COUNT          146 a           84 c           67 g          116 t
ORIGIN      
        1 catctttttt attttccaaa acatatagaa aagacacctt gaaatccttt agaattaatt
       61 tggcgaacca acccaaaagg aggaatcaag atgtcttaca ctcaccttat caaagaaaca
      121 ttagatattc tagacttatc agttactttt aacgaaaatt gtctcacaaa agaaaaatac
      181 aaagggcaaa tctgtcatat ttatcgtgga aacttgattt atacagccca agaatgcatc
      241 cactgtaaac accagattgc ttcagatatt gtgcgttggg gtacaacaac cgtccggttg
      301 ttaatgaacg atgtttctga ataccgtacc tacctcgaat tgaaaaagca acgcttcaaa
      361 tgcaaagctt gtcagcggac ctttgtcgca gatacttctg ttgcgaaaaa aca
//
LOCUS       DAIGQM010000205          413 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.216, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000205 DAIGQM010000000
VERSION     DAIGQM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.216"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            4..>413
                     /gene="mobC"
                     /locus_tag="NOA48_002817"
     CDS             4..>413
                     /gene="mobC"
                     /locus_tag="NOA48_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HCI0790992.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDI"
BASE COUNT          161 a           55 c           82 g          115 t
ORIGIN      
        1 tcaatggatg ataaacaaaa aatgtacgaa aaaaatcgca aacatagtga ggccttaaat
       61 tttcgtgtcg ataaaaagac ttatcttgaa ctgacattga ttgcaaaaca aaggggaatt
      121 tctagagcag acgtttgccg tgagcggtta aagggactca aatatgaacc gccgttgtta
      181 gctgaagatg atagggtagt tttaaccaaa cagttaaatc aaattggtaa caatttgaat
      241 caagcggtaa aggcattaaa tatcattgct aaatatttta gagaagaatc tgaagataaa
      301 aaagaaaaga gcctacattt tagttttgat gctagccgtt acaacatttt taaagatgaa
      361 cttgcgaata gcatagcaaa aaagttgatg attagttatc cagatgacat ttt
//
LOCUS       DAIGQM010000206          404 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.217, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000206 DAIGQM010000000
VERSION     DAIGQM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.217"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>404
                     /locus_tag="NOA48_002818"
     CDS             <1..>404
                     /locus_tag="NOA48_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0790993.1"
                     /translation="PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDK
                     SDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVV
                     VTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          166 a           60 c           92 g           86 t
ORIGIN      
        1 ccagaagata aacttccagt gttgaaagca aaagatggtt atacagatgc gaaatggcca
       61 gaggaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
      121 ctggatgata aatctgacgc tgacaaatat aatcctgaag gtcaaaaagt gactacagaa
      181 ttgaataagg aaccagacgc atttgaggga attaagaaca aagaagattt accaaaagat
      241 actaagtata cttggaaaga aaaagtagat gttagcgcag ctggaaataa aaaagggact
      301 gttgtagtga catatccaga tggatcatct gatgaagttg aagtagatgt tacagtgaca
      361 gacaatcgtt ctgacgccga taaatatgag ccaacagtag aagg
//
LOCUS       DAIGQM010000207          403 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.218, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000207 DAIGQM010000000
VERSION     DAIGQM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.218"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..210)
                     /locus_tag="NOA48_002819"
     CDS             complement(<1..210)
                     /locus_tag="NOA48_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0790994.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT          126 a           76 c           49 g          152 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg ttt
//
LOCUS       DAIGQM010000208          398 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.219, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000208 DAIGQM010000000
VERSION     DAIGQM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.219"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>398
                     /locus_tag="NOA48_002820"
     CDS             <1..>398
                     /locus_tag="NOA48_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790995.1"
                     /translation="INTLLRTELTAFLDYEKYDRTGFNSGNSRNGSYFRSIKTEYGEL
                     TLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTP
                     QTMSNMTKVLTEEVNAFKSRALNDKYVAIF"
BASE COUNT          145 a           73 c           65 g          115 t
ORIGIN      
        1 cgataaacac actcctacgg actgaattaa cggctttttt agattacgaa aaatatgatc
       61 gcactggttt taattcaggt aattcgagaa acggttctta ctttcgatca atcaaaaccg
      121 aatatggtga attaacattg gaaataccta gagatcgtaa tggtgagttt aaacaacaaa
      181 ctttaccagc ctacaaaaga acaaacgata cattggaaac cactattatc catttattcg
      241 aaaaaggtgt tacgatgtct gaaattgctg atttgatcga aaaaatgtac ggtcatcact
      301 atactccaca aaccatgtcc aacatgacta aagttctgac tgaagaagta aatgccttta
      361 aatccagagc cttaaatgat aagtatgtcg ctattttt
//
LOCUS       DAIGQM010000209          381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.220, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000209 DAIGQM010000000
VERSION     DAIGQM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.220"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(21..94)
                     /locus_tag="NOA48_002821"
     tRNA            complement(21..94)
                     /locus_tag="NOA48_002821"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="NOA48_002822"
     tRNA            complement(108..181)
                     /locus_tag="NOA48_002822"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="NOA48_002823"
     tRNA            complement(209..281)
                     /locus_tag="NOA48_002823"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="NOA48_002824"
     tRNA            complement(301..374)
                     /locus_tag="NOA48_002824"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DAIGQM010000210          380 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.221, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000210 DAIGQM010000000
VERSION     DAIGQM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.221"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..376
                     /locus_tag="NOA48_002825"
     CDS             <1..376
                     /locus_tag="NOA48_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0790996.1"
                     /translation="ICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQD
                     LLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          146 a           70 c           57 g          107 t
ORIGIN      
        1 aatctgtgat gactttaagg ctgtttatca agctaactca aaagaagaag cgaatacctt
       61 cttatccggc atgattgaga aatggaagaa aaactatcct aaagtgacgc agtcactcat
      121 agaaaaccaa gacttattaa ctttttatga ttttccacct agcattcgta gaaccattta
      181 ctcaaccaat ctaatcgagt ctttcaataa gcaaattaaa agatacagcc gtagaaaaga
      241 gcagtttcaa aatgaagaat cactagaacg ctttctagtc agcatttttg atacatacaa
      301 tcaaaaattt ctaaacagaa gccataaagg ttttcaacag gtaaccgata cattagtttc
      361 aatgtttact gagtaactaa
//
LOCUS       DAIGQM010000211          380 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.222, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000211 DAIGQM010000000
VERSION     DAIGQM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.222"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..351
                     /locus_tag="NOA48_002826"
     CDS             <1..351
                     /locus_tag="NOA48_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0790997.1"
                     /translation="REAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGF
                     EDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHD
                     EWIYSSRKYINFDK"
BASE COUNT          142 a           66 c           66 g          106 t
ORIGIN      
        1 agagaagctg ttaaaggaat ttttaagttc acagatatta acttagcgcg tgaggctaaa
       61 aatcgattga ttcatgatta tatcgatcaa ccaaaatatt caaaagcttg cgcatcattg
      121 gatgatggat tcgaagacgc ctttcaatat accgtacaag gaaattccca caatcgacta
      181 aagagtacca atctaattga acgactgaat caagaagtac gcagaagaga aaagattatt
      241 cgcatcttcc ccaatcaaac atcagccaat cgcttaattg gagccgttct tatggaccta
      301 catgatgaat ggatttattc ttcaagaaaa tacatcaatt ttgataagta gaaatggtaa
      361 aaacattgta tagcatttta
//
LOCUS       DAIGQM010000212          376 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.223, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000212 DAIGQM010000000
VERSION     DAIGQM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.223"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>376
                     /locus_tag="NOA48_002827"
     CDS             <1..>376
                     /locus_tag="NOA48_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0790998.1"
                     /translation="KRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEFGHLEGDTIVG
                     IHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFKSITFDCGKEF
                     SNWKAISNQHDIDIYFADPGTPS"
BASE COUNT          124 a           76 c           65 g          111 t
ORIGIN      
        1 gtaaaagaaa acccaatggc catcaggaaa aacggggaaa acaacagtat cagcgctcaa
       61 tccatgatcg acctgataat tatcctgatt tcaattctga gtttggtcac cttgaaggtg
      121 atacgatcgt tggcattcat cataaaagtg ccgtcattac tttagttgaa agattatcta
      181 aagtcattat cacgattaaa cccaacggcc gtaaggcatt agatattgaa actgccctta
      241 atcaatggtt ttctcgcttc cctaaaaact tctttaaatc tattacgttt gactgtggaa
      301 aagaattttc taactggaaa gccattagta accaacatga tattgatata tattttgcgg
      361 accctggaac accttc
//
LOCUS       DAIGQM010000213          375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.224, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000213 DAIGQM010000000
VERSION     DAIGQM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.224"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..132)
                     /locus_tag="NOA48_002828"
     CDS             complement(<1..132)
                     /locus_tag="NOA48_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0790999.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAIGQM010000214          349 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.225, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000214 DAIGQM010000000
VERSION     DAIGQM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.225"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(44..>349)
                     /locus_tag="NOA48_002829"
     CDS             complement(44..>349)
                     /locus_tag="NOA48_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0791000.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAIGQM010000215          340 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.226, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000215 DAIGQM010000000
VERSION     DAIGQM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.226"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>340
                     /locus_tag="NOA48_002830"
     CDS             <1..>340
                     /locus_tag="NOA48_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0791001.1"
                     /translation="MTKVLTEEVNAFKVRTLNDKYVAIFMDATYIPLKRQTVSKEAIY
                     IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDVLLFITDGLKGMKDTIH
                     QIYPKAKYQHC"
BASE COUNT          113 a           61 c           66 g          100 t
ORIGIN      
        1 atgactaaag tgctgactga agaagtaaat gcatttaaag ttagaactct aaatgataag
       61 tatgtcgcta ttttcatgga tgctacttat attcctttaa aacggcaaac cgtctccaaa
      121 gaagcaatct atattgccat tggtatacga gaagacggca ctaaagaagt actaagttat
      181 gcgattgctc cgactgaatc gacctacgtt tggaatgagt tgttacagga catttactcc
      241 agaggggttc atgatgtctt actgtttatt accgatggct taaaaggcat gaaagatacg
      301 attcaccaga tttatcctaa agctaaatac caacattgct
//
LOCUS       DAIGQM010000216          336 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.227, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000216 DAIGQM010000000
VERSION     DAIGQM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.227"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..249)
                     /locus_tag="NOA48_002831"
     CDS             complement(<1..249)
                     /locus_tag="NOA48_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0791002.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRT"
BASE COUNT           86 a           61 c           60 g          129 t
ORIGIN      
        1 ggttcgtgga acatgaagtt ctaacgtacc aattcgagtt gtaaacgaac gatcgtagta
       61 accatttctt tgtgattgcc gttcttctga acgttcatag gcatttgcct gaatatattg
      121 atttcgttgt tcttccatca gctgattaaa catgatagtc ataagtgttt ttgcggtatc
      181 attcgcaccg ctttcgttta taattgcttg aatttcttcg ctttcaaaag taaaatgtac
      241 ttgagtcatt gatatcagtc ctattcgagt atgttttctg caaaaaacat tgtactccta
      301 actgagatca atggcttttt tgatgcttca ctttta
//
LOCUS       DAIGQM010000217          334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.228, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000217 DAIGQM010000000
VERSION     DAIGQM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.228"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..165
                     /locus_tag="NOA48_002832"
     CDS             <1..165
                     /locus_tag="NOA48_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791003.1"
                     /translation="KKFDSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDP
                     NPLFDNLLKK"
     gene            180..>334
                     /locus_tag="NOA48_002833"
     CDS             180..>334
                     /locus_tag="NOA48_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791004.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIE"
BASE COUNT          146 a           39 c           58 g           91 t
ORIGIN      
        1 aaaaaatttg attcaaatca tgaaacagtg attattgata gtgaaatccg tgaaaatgat
       61 aagggatcaa aatcaagacg aagattcact tatgaagaca atgagttatt cagagataca
      121 cttaatgatc ctaatccact tttcgataat ctattaaaaa aataaaaggg gggattgtca
      181 tgcaattaat tctaaagatt agtacgcatg atttcttaga acttgacgaa ttatgtgaat
      241 cagtaaagaa cgcaacaaat gaaaaaatca cggtcactaa ttatattgaa ctgatgattc
      301 aagaagaatt aaagatgaaa aatgaaatag agag
//
LOCUS       DAIGQM010000218          332 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.229, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000218 DAIGQM010000000
VERSION     DAIGQM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.229"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>332
                     /locus_tag="NOA48_002834"
     CDS             <1..>332
                     /locus_tag="NOA48_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791005.1"
                     /translation="IILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVT"
BASE COUNT          103 a           53 c           78 g           98 t
ORIGIN      
        1 attatacttt ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa
       61 aagtatcatg tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta
      121 aaaaatgcag aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt
      181 ggtttatctg tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct
      241 cttggatact taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc
      301 gaacaaggat tatatggttg gaatgtgacg ga
//
LOCUS       DAIGQM010000219          321 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.230, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000219 DAIGQM010000000
VERSION     DAIGQM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.230"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>321
                     /locus_tag="NOA48_002835"
     rRNA            <1..>321
                     /locus_tag="NOA48_002835"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          108 a           64 c           87 g           62 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac t
//
LOCUS       DAIGQM010000220          319 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.231, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000220 DAIGQM010000000
VERSION     DAIGQM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.231"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            66..>319
                     /locus_tag="NOA48_002836"
     CDS             66..>319
                     /locus_tag="NOA48_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0791006.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           94 a           57 c           62 g          106 t
ORIGIN      
        1 ggatgatgtc tacagtcttt tcttttataa tagatttatg aaaacgaatg caaggagtga
       61 tagctatgat gtctaaaaac aatacgaatg gtagaaatca atttgcgatg cttacgattg
      121 atgatctagt tcctcaagat catctcgttc gaaagattga tgccgcgctt gattttgaat
      181 ttatttatcc aatcgtcgaa gccacttact ccgatttagg tcgcccaagt atcgatccag
      241 tgattctgat caaattggtg tttattcagt atttattcgg tatccgttcc atgcgacaaa
      301 ccattaagga agtcgatac
//
LOCUS       DAIGQM010000221          309 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.232, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000221 DAIGQM010000000
VERSION     DAIGQM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.232"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOA48_002837"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOA48_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCI0791007.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           97 a           45 c           50 g          117 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatat
//
LOCUS       DAIGQM010000222          304 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.233, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000222 DAIGQM010000000
VERSION     DAIGQM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.233"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(128..274)
                     /locus_tag="NOA48_002838"
     CDS             complement(128..274)
                     /locus_tag="NOA48_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791008.1"
                     /translation="MILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
BASE COUNT           99 a           68 c           29 g          108 t
ORIGIN      
        1 cttatttatt actagtgttt caagcggatc aactttattt tcttcagcca ctcttccaat
       61 ttcctcactt tcattttcaa aaatcacaaa aatgatatta acttaaaagc cactaacaaa
      121 ataagactta caaagtaaag ggtaatccaa caaaataacc attcgctcta cgtactacga
      181 tttggtagtc ctgcctttca atcggtaatt cataatagta atttactgtt tcttctttgc
      241 cactttcaat atactctgga ttatccaata tcatagcata ctcataaagt tcttcaccat
      301 cctt
//
LOCUS       DAIGQM010000223          292 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.234, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000223 DAIGQM010000000
VERSION     DAIGQM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.234"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..185
                     /locus_tag="NOA48_002839"
     CDS             <1..185
                     /locus_tag="NOA48_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0791009.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           83 a           63 c           69 g           77 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      241 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tc
//
LOCUS       DAIGQM010000224          287 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.235, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000224 DAIGQM010000000
VERSION     DAIGQM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.235"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>287
                     /locus_tag="NOA48_002840"
     CDS             <1..>287
                     /locus_tag="NOA48_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0791010.1"
                     /translation="QRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIK
                     KLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKI"
BASE COUNT           98 a           53 c           45 g           91 t
ORIGIN      
        1 caaagagcca cgtatagagc ggtttgttcc gtcttatttc ctaatggtga ctttcctagt
       61 aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat tattcgatac
      121 tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag ttttcctagt
      181 ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat agccaaagtt
      241 ggctataact caacaaaaaa atcttatttt tatggtctta aaattca
//
LOCUS       DAIGQM010000225          265 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.236, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000225 DAIGQM010000000
VERSION     DAIGQM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.236"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>265
                     /locus_tag="NOA48_002841"
     CDS             <1..>265
                     /locus_tag="NOA48_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HCI0791011.1"
                     /translation="KAGFVTEDNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDELED
                     EINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGER"
BASE COUNT          106 a           44 c           61 g           54 t
ORIGIN      
        1 aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat caaagctaac
       61 gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc ctatcaggat
      121 gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc ttttactttg
      181 gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga tccggaaagc
      241 ggctactacg tcaaaggcga acgag
//
LOCUS       DAIGQM010000226          249 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.237, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000226 DAIGQM010000000
VERSION     DAIGQM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.237"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            9..>249
                     /locus_tag="NOA48_002842"
     CDS             9..>249
                     /locus_tag="NOA48_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HCI0791012.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLF"
BASE COUNT           79 a           51 c           63 g           56 t
ORIGIN      
        1 tgatctcaat gaaaaaaatg tacgaaacag caatgatcaa tcgtggaggc cgtgatggcg
       61 aggttgaggc accaaacgga agtatgcaca tgaagatcga ccgcccagga atccatagtg
      121 aagggacaaa tccggaacaa ctttttgcgg ctggatacgc atcttgcttc aacggcgcgg
      181 ttcaacacat gctggaagaa aataatcttg agtctgattc tgaagtcaaa gcacgggtat
      241 ctttatttc
//
LOCUS       DAIGQM010000227          248 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.238, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000227 DAIGQM010000000
VERSION     DAIGQM010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.238"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
BASE COUNT          117 a           30 c           37 g           64 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaa
//
LOCUS       DAIGQM010000228          240 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.239, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000228 DAIGQM010000000
VERSION     DAIGQM010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.239"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>240
                     /locus_tag="NOA48_002843"
     CDS             <1..>240
                     /locus_tag="NOA48_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0791013.1"
                     /translation="LEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHTIGRDEHTVS
                     HYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQ"
BASE COUNT           76 a           61 c           62 g           41 t
ORIGIN      
        1 ttggaaaaag cgatgaatac gacagacaac cgccggttgt acgagcgttt cctggcagtc
       61 aagttggttc ttgaaggcca cacccggaaa gaagccgggc acaccatcgg ccgcgacgag
      121 catactgtca gccactatgt gaaaaactac tgccataatg gaatccaagg tttagtctcc
      181 aaaaaacaaa gcggacgacc ttcacggctg acagatgaac aggaagcgga actggtccaa
//
LOCUS       DAIGQM010000229          227 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.240, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000229 DAIGQM010000000
VERSION     DAIGQM010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.240"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            1..227
                     /locus_tag="NOA48_002844"
                     /pseudo
     CDS             1..227
                     /locus_tag="NOA48_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           94 a           43 c           44 g           46 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc atatcagcga tgtgcaa
//
LOCUS       DAIGQM010000230          226 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.241, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000230 DAIGQM010000000
VERSION     DAIGQM010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.241"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..226
                     /locus_tag="NOA48_002845"
     rRNA            <1..226
                     /locus_tag="NOA48_002845"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           66 a           38 c           66 g           56 t
ORIGIN      
        1 gatggactta ccgctggtgt accagttgtt ctgccaaggg cattgctggg tagctatgta
       61 gggaagggat aaacgctgaa agcatctaag tgtgaagccc acctcaagat gagatttccc
      121 atttctttaa gaaagtaaga tccctgagag atgatcaggt agataggtca ggagtggaag
      181 tacagtgatg tatggagcgg actgatacta atcgatcgag gactta
//
LOCUS       DAIGQM010000231          226 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.242, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000231 DAIGQM010000000
VERSION     DAIGQM010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.242"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            1..226
                     /locus_tag="NOA48_002846"
                     /pseudo
     CDS             1..226
                     /locus_tag="NOA48_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           36 c           43 g           68 t
ORIGIN      
        1 gtgtcaaaga tcgaaaagaa atctgtgatg attttaaggc tgtttatcaa gctagctcaa
       61 aggaagaggc aaataccttt ttagggagta tgattgagaa gtagcaaaaa acttatccta
      121 aagtgacgca gtcactgata aaaaatcaag atttattgac tttttatgag tttccgcctg
      181 gtatccgccg aagcatttac tcaactaatt taatcgaatc tttcaa
//
LOCUS       DAIGQM010000232          214 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.243, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000232 DAIGQM010000000
VERSION     DAIGQM010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.243"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
BASE COUNT           87 a           25 c           38 g           64 t
ORIGIN      
        1 aaagcttcga aatccattgg catttcgttg gaataccttg atatgattat tcaaatataa
       61 aatatagaga gaagagagag agggaagata tttataaagg gcaaagttat gtttactcaa
      121 cttaggaaat agaaatagat caatttatat tctcttgtca atcgaatatg aaccttagca
      181 ctatatacca aatatagtaa aatgctgaaa gatg
//
LOCUS       DAIGQM010000233          209 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.denovo.244, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000233 DAIGQM010000000
VERSION     DAIGQM010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.denovo.244"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..>209
                     /locus_tag="NOA48_002847"
     CDS             <1..>209
                     /locus_tag="NOA48_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0791014.1"
                     /translation="RWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRT
                     PLPKVLCFDEFKSVRGVSGAMSFIM"
BASE COUNT           51 a           43 c           44 g           71 t
ORIGIN      
        1 cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa tgacagagat cgccgctcag
       61 aaaaatctat cggtctcttc tgtttaccgt attatgaagc gattttatcg tccgttgaat
      121 ccttttcgga caccgttacc taaggtactt tgttttgatg aattcaaatc agttcggggt
      181 gtttcaggtg ctatgagttt catcatgat
//
LOCUS       DAIGQM010000234        20862 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.054, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000234 DAIGQM010000000
VERSION     DAIGQM010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.054"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            267..1304
                     /locus_tag="NOA48_002848"
     CDS             267..1304
                     /locus_tag="NOA48_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0791015.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="NOA48_002849"
     CDS             complement(1393..1716)
                     /locus_tag="NOA48_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0791016.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="NOA48_002850"
     CDS             complement(1703..2410)
                     /locus_tag="NOA48_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0791017.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="NOA48_002851"
     CDS             2496..2837
                     /locus_tag="NOA48_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI0791018.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="NOA48_002852"
     CDS             complement(3008..3856)
                     /locus_tag="NOA48_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791019.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="NOA48_002853"
     CDS             4454..5317
                     /locus_tag="NOA48_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0791020.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="NOA48_002854"
     CDS             5417..5899
                     /locus_tag="NOA48_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI0791021.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="NOA48_002855"
     CDS             complement(6162..6629)
                     /locus_tag="NOA48_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI0791022.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="NOA48_002856"
     CDS             6752..7603
                     /locus_tag="NOA48_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0791023.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="NOA48_002857"
     CDS             complement(7854..9812)
                     /locus_tag="NOA48_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0791024.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="NOA48_002858"
     CDS             complement(9809..10681)
                     /locus_tag="NOA48_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0791025.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="NOA48_002859"
     CDS             complement(11023..11895)
                     /locus_tag="NOA48_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0791026.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="NOA48_002860"
     CDS             12023..12592
                     /locus_tag="NOA48_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0791027.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="NOA48_002861"
     CDS             12659..13396
                     /locus_tag="NOA48_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0791028.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="NOA48_002862"
     CDS             13627..14895
                     /locus_tag="NOA48_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0791029.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="NOA48_002863"
     CDS             15382..15846
                     /locus_tag="NOA48_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0791030.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="NOA48_002864"
     CDS             15830..16459
                     /locus_tag="NOA48_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0791031.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="NOA48_002865"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="NOA48_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0791032.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="NOA48_002866"
     CDS             18338..18784
                     /locus_tag="NOA48_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0791033.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="NOA48_002867"
     CDS             complement(18983..19498)
                     /locus_tag="NOA48_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0791034.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="NOA48_002868"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="NOA48_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAIGQM010000235        18683 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.059, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000235 DAIGQM010000000
VERSION     DAIGQM010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.059"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            102..998
                     /locus_tag="NOA48_002869"
     CDS             102..998
                     /locus_tag="NOA48_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI0791035.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1148..2089)
                     /locus_tag="NOA48_002870"
     CDS             complement(1148..2089)
                     /locus_tag="NOA48_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0791036.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2215..3336
                     /locus_tag="NOA48_002871"
     CDS             2215..3336
                     /locus_tag="NOA48_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0791037.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3594..5096
                     /gene="eat(A)"
                     /locus_tag="NOA48_002872"
     CDS             3594..5096
                     /gene="eat(A)"
                     /locus_tag="NOA48_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0791038.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5124..5690
                     /locus_tag="NOA48_002873"
     CDS             5124..5690
                     /locus_tag="NOA48_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0791039.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5901..6962
                     /locus_tag="NOA48_002874"
     CDS             5901..6962
                     /locus_tag="NOA48_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0791040.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6965..7861
                     /gene="murQ"
                     /locus_tag="NOA48_002875"
     CDS             6965..7861
                     /gene="murQ"
                     /locus_tag="NOA48_002875"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI0791041.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7875..9857
                     /locus_tag="NOA48_002876"
     CDS             7875..9857
                     /locus_tag="NOA48_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0791042.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9922..10368)
                     /gene="nrdI"
                     /locus_tag="NOA48_002877"
     CDS             complement(9922..10368)
                     /gene="nrdI"
                     /locus_tag="NOA48_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI0791043.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10579..12003
                     /locus_tag="NOA48_002878"
     CDS             10579..12003
                     /locus_tag="NOA48_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0791044.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(12184..12957)
                     /locus_tag="NOA48_002879"
     CDS             complement(12184..12957)
                     /locus_tag="NOA48_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0791045.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12954..13859)
                     /locus_tag="NOA48_002880"
     CDS             complement(12954..13859)
                     /locus_tag="NOA48_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0791046.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(14013..14333)
                     /locus_tag="NOA48_002881"
     CDS             complement(14013..14333)
                     /locus_tag="NOA48_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI0791047.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14807..15493
                     /locus_tag="NOA48_002882"
     CDS             14807..15493
                     /locus_tag="NOA48_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI0791048.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            15495..16439
                     /locus_tag="NOA48_002883"
     CDS             15495..16439
                     /locus_tag="NOA48_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI0791049.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            16638..17282
                     /gene="pcp"
                     /locus_tag="NOA48_002884"
     CDS             16638..17282
                     /gene="pcp"
                     /locus_tag="NOA48_002884"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI0791050.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            17361..18638
                     /locus_tag="NOA48_002885"
     CDS             17361..18638
                     /locus_tag="NOA48_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791051.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5989 a         3300 c         3983 g         5411 t
ORIGIN      
        1 atgttaaatt ttcatacaaa tataggaaac gttttactgg ctttttacta tttaaacagg
       61 ctatcatagg aaaaagtgac agagaaagtg aggcggaaaa gatgaacaaa aatgacgtac
      121 tgctagttgc aaaaaataaa tcactttatt ttttgccttc catccgctct ttagatgttt
      181 ggtccggaaa agatttacta cagtcggaat tcattaaatc agctagacaa cagttggcaa
      241 attatcagct gatcgttttt ttagattatg gatttgatat ggagatggct cgacgcgtgc
      301 gcccatttac caatgcaaaa attgtgttat ttttttggaa tcacttcaaa gcagaacacg
      361 aggcgatgct gaagcaggca caagatgaac cggcaatcga tgagatttat cattttgatt
      421 ttttggaagc aaaagaactt gggctgaaac ataatagttc attttattcg aaacatatga
      481 atttttcttc tagcgaacca aagacggatc tattttttgg tgcaacgaat aatgggagaa
      541 aagaacgagc agaaagctat aagcaggaat ttataaaaag agatgttacg accaactatt
      601 tcattcttcc acatcgaggg aatgaacaac ctggatatct tacttatgaa gagtacctga
      661 aaaaaacagg ggaatcgcgc gggattctgg aactgttgcg ggagggtcag caaggagtga
      721 ctttgcggac atttgaatcc atgtattttc aaaagaaact agtgacggat aatcaagcga
      781 ttgctcatta tcatttttat cgtcctgaaa atattttttt gcttcgagaa cgtgatttag
      841 atgaattacc ggaatttctg catacaccat ttaagccaat cctatcagag ctattggaat
      901 tttatgatgc agaaaattgg gcaaaacgat ttatcactaa cgattccact atttatgagc
      961 aatacgaata tgacctctcc tctgttgaaa acaaataaaa aacctacatt ttgaagagat
     1021 tatgtactga aacaaacaag cacaattctt atggcatcat gagagttgtg ttttcttttt
     1081 gatcttttat tgggcttaaa aaaagagaac cagctgctga ttcagctgat tctcatcaga
     1141 gagcctttta ttctgcgcca aggattcctt cttttgcatg gactaattgg gtcaaaaagg
     1201 cacaatatgg tgtagcaata tcatattttt gtccttttcg ccaaatggca ccattgatgt
     1261 agtcgatttc agtcaaacga tggtttttga tcaggtcttg gtacatagat gggtaatgca
     1321 acccgatgtt gtcaggatca taagtagaag caatatgttg gtacacttct tcttgatcta
     1381 gtatgattcc ttcttttgct gcgatagaag caaattcaga tacgattgtt cgaaccatgc
     1441 tctctgccgc tttttgcgcg cctagttcag caatattaca atccaaaatc gtgcataaac
     1501 cattcaatgt tccatttaca caagcttttc gccaaatgga ataacgaacg ttatggctat
     1561 agatcggatt taaatttgct tcttgaaaga cttctacaac tttttttgta aatgcttcgc
     1621 cttctggttc caagttctct agttcgattt ctccatcacc taacaatgtg acttttccgg
     1681 gaccagctag accagctgtc cacatcgtga tcccaaataa gatatttttc tttggcacat
     1741 atttttccag tacatcttca tgacctaatc catttagtaa acacaaaaca taagtattgt
     1801 cagtaataat ggattggatc gaacaaaaca tatcatctaa ttgattggct tttgttaatg
     1861 ctacgatcaa gtccacgtgt tcgttgcttt cgatgatttc ttctggtgaa tagattggca
     1921 gttttgcgac cacttcttta ccgttaaagt cagcaatcaa cccatttgta cgaatggctt
     1981 caatgtgagc aggccaacga tcgatcaaga ggacctcatt tccgctttga tgtagcatca
     2041 atccgattcg gctgcccatt gctccggccc cagctattgc gattttcatg ttttttctct
     2101 cctttattca atgagttccc ttttagtata tagaaaaatg gaagaaaata gcattgtttt
     2161 gtttgaaaaa aatgaaaaaa agtgtcttac ttaagaagaa agtgagggat acagatggat
     2221 attttggcgg caattgattc atttaaagga agtgcttctt catttgaact aaatcaggca
     2281 gttctaaatg gctgggaaga tcgtaaagga agaaaaatca atgtgccgat tgcagatggc
     2341 ggagaaaata ctgcagaagc aatctattac gcgctcaggg gaacatggcg taccattgat
     2401 gggatggatc tcttattccg tcagcgaaaa atcagctatt tattgacaac ttggcaagga
     2461 aaaaacaccg cagtcatcga atctgcacaa gcattggggt tagatctact tgataaacca
     2521 acggatcaaa ctatccgact tgcttccagt tatgccttag gagaacttat taaagatgca
     2581 ctgcttcaag aagtagaaca aattattgtc actttaggag gaagcgggtg tagcgatggt
     2641 ggtctaggat tactccaatc cttgggtgct tctttagaag ggtacacaga aggaaatcct
     2701 ttattatcta ctaaaaaact tcattttgat cgaagaaacg ttcttgtttc taaagtaaaa
     2761 ttgattatcg ctgcagatgt taccaatcca tatacaggtc aacaaggagc tgcttggcaa
     2821 tttggaagac aaaaaggagg aatagatacg acgctagctt tcttagataa acaagcagga
     2881 aagattgctc agcaaataaa agatttctgg gaggtggatt tagatgatat tccaggaagt
     2941 ggagcagcag gcggtattgg tggagccctt tttttgttgg gagcgaagat ggtttctggt
     3001 ttcgatttag tcagccaaat cactggattg gaaaaaaaga tcgaacaagc agatgtcatc
     3061 attacaggag aagggcggat cgatcagcaa acgatccacg gaaaagttcc atacggtgta
     3121 gcagtgcttg caaaaaaata tcgaaaacca ataatcgcta tttgcggaag tagagaccaa
     3181 gagctagaag gactttctga ttttctccca attgtcttaa gtattcattt gggtccaata
     3241 ggtttagaag aagcaatgga acacaggcaa acattagaaa aaacaaaaat cttaggacag
     3301 acacttagca gatttttcac catcctcccg aagtagttga caaaatcatt ttctttatgc
     3361 tatcgtaatt tcaaatatag gacaaagtga gggatccgtg cattgaaaaa ttaagtcgat
     3421 tgatgaaagc tgcattcaga ctgtaccttg tggagacaag gaagcagtgt gcagattttc
     3481 gggattggct tggttttttc gatgtatggg tctttttgtg tgtatccaac ccttgcatcc
     3541 tctttagcca gttctgaaaa taggactggt ctttttttac gaggtgatgg aaaatgtcta
     3601 aaatcgaaat aaaaaatctg acattcggct acgacagcca aggcacatta ttatttgaac
     3661 aagcaaatct aaattttgac acacaatgga aactaggact tatcggacga aacggtcgag
     3721 gaaagacaac tttactgaat attctacaaa acaaactacc ttatcaaggg caagtaatcc
     3781 atcagcaaga atttgcctat ttcccgcaac agacaaaaga taaagaacgt ttaacctatt
     3841 acgtgttaaa tgatattacg gattttgaga tatgggaaat cgaaagagag ctccaattga
     3901 tgcaaacaga tcctgaaatc ttatggagag aattcagcac actatcgggg ggagagaaga
     3961 caaaagtcct actggcactt ttatttgtgg atgacactca tttcccgtta atcgatgaac
     4021 caacgaatca tttggatatc tctggtagaa aacaagtagc ggcttatttg aaaaagaaaa
     4081 aacaaggctt catcgtggtc agccatgacc ggggatttat cgatgaagta gtggaccatg
     4141 ttttagcaat cgaaaaaagt caactggaac tttatcaagg gaatttctct atctatgaag
     4201 aacagaaaaa acttcgtgat gaatttgaaa tggctcaaaa tgaaaaattg aaaaaagaag
     4261 tcagtaggct aaagaaaaca gcagctgaaa aagccgaatg gtctcgttcc cgagaaggag
     4321 ataaaacaaa gaaacaagtc ggattcatcg atactgaatc tagacgagtg aataaaggag
     4381 cagtgggtgc tgatgctgca cggacgatga aacgatccaa agcaatcgtg aatcggatgg
     4441 agacccagat cagcgagaaa gaaaaactat taaaagatat cgaatatatc gattctttga
     4501 cgatgaatag ccaagcgtct caccataagc gacttttaag cgtagaagat cttcaattag
     4561 ggtatgaaaa tctgttattc gagccaattc attttacaat cgagcctcat cagcgggtgg
     4621 cgatttcagg tcctaacggt gcaggaaagt catccattat ccattatctt ctgggggcat
     4681 tcaacggcaa ggttatagga gaaaaatacc agccaaaaca tctgagcatt agttatgcaa
     4741 gccaaaatta tgaagacaat cgaggaacgt tggcggaatt tgcagagaaa aaccaagtag
     4801 actaccaagc atttttgaac aacctccgaa agcttgggat ggaaagagat gtttttcata
     4861 acaagatcga gcagatgagt atgggccaac ggaaaaaagt ggaattggct aaatctttat
     4921 cacagccagc tgaactatat acatgggatg aaccattgaa ttatttggat gtcttcaatc
     4981 aagaacaatt agaacaactg atcttgaacg tgaaacctgc catgttacta gtggaacatg
     5041 atcaaacctt cctggataaa gtatctactg agattatttc tcttgagaga atctaaccct
     5101 tgtaatctca agaacaacaa ggtatggtta aggggaactt tgccaacgaa ggagagaatc
     5161 acatgcttta tgtaacgaga cacggagaaa caacttggaa cgcacaagga ttagtttgcg
     5221 gacgggcaga tgtgccgctg actgaaaaag gacagatgca ggcacagaaa ctagcagaaa
     5281 aggtagtaga tttgcctgtt ccaatcacga aaatcatcca ttcccctctt caacgagcaa
     5341 gagatacagc acaagcagtt gctgatcgtc tcagcttgcc gctgaccgtt gatgaacgat
     5401 tggtagaaat ggattttggg gattatgatg gactgccaag caaagatgag aactttcaaa
     5461 aagcacgttt agcgttcgct gtacgattcc caaatgggga gtcagtctta gatgtgtatg
     5521 cacggatcgt tcctttattg aaagaatgca tcgaagacga agaaaatgtc tatctgttag
     5581 tttgccataa tgccttgata agagtgatca atgcttattt tcatccgatg cctaatgagg
     5641 ggttctttac attcatggta gataatacag aattggtttc ttatgagtaa ttatgttttt
     5701 gtgttattta aataaaatat ttcaaggcac tgcttttgct tagcagtgcc ttttttaggt
     5761 tatgacaatt cttttgataa tataaactca acctttagaa atgaaattta attattttaa
     5821 taaaagtatt gaaattttgt ttctttagat atatactcta gtcatagaaa tgaagacgga
     5881 tacagaaaaa gagggataat atgtttggct tttcaatatt tatgaacgat tctttgtcag
     5941 aagagaagaa acagtatatc cgccaaatgg catccaatgg ctttgtcggt attttcactt
     6001 ccatgcatat accagaagat gatgtttcgg catatcaaaa gcgattgatc gaactaggaa
     6061 gcgaagcgaa aaagaataaa ctagaattga tggtcgatat ttcaggagag gcattggaac
     6121 gagcgggttt ttcattagaa gatctaacgc ctttgaaagc aattggtgta acaggtttaa
     6181 gaatggatta tcatatttcc aatcagcaga ttgccgactg gtcacatcaa ttgaaaatca
     6241 gtttgaatgc tagcacgatc acgcctaaag atatcgatga attgaaagaa gcagaagctg
     6301 atttctcaca gattgaagct tggcataatt attatccacg tcccgaaaca gggctggaca
     6361 aagaatggta tcagaaaaaa aatcaatggc tcaaaattca aggtctcctt gtccaaggtt
     6421 ttgtaccagg agatacagag ttgagaggcc cactatatca aggattgcca actttggaag
     6481 aacatcgagg gatccatcct cttgcaggcg ctctagatct attagcaagt aacacggata
     6541 ttgtttacat cggagatgca ggtctgtcag aaaacgttca ggagcaattt gcttctttcc
     6601 aaaaagaaca gacagtcttg ctccatacgg aacctgtaga tgaagaattt tacgaatata
     6661 tattagggaa gcatacgaat cggcaagacg atgcaagaga tgtcatacga agcgtagatg
     6721 cacgttttcg agagattccg cctatcccag caagaaatac agctacgcgt atgaaagggt
     6781 ctattacttt agataacgaa aagtatttgc gctatatggg tgagatccaa ttaaccaaat
     6841 atgatttgcc agcggatgaa aaagtgaatg tagtagctaa agttatcaaa gaagagctac
     6901 cattgatcaa ccaaatcaaa gctggtatga actatcaatt tataagaaaa gaaggaagat
     6961 aaaaatgagc aaaatcaatt tagagaacct aacaacggaa cgcagaaacc aagaaacttt
     7021 tggattagat gagatgagta tttctcaagc cgttcaacta atgaacaaag aagatcagaa
     7081 agtggccgct gcggttgaaa aagaactgac aagtatcgaa ccagtgattg ctaacacgat
     7141 tgagtccttt aaaaaaggtg gacgtctgat ttatatggga gccggaacaa gtggaagact
     7201 aggtgtgtta gatgctgctg aatgcgtacc gacattcggt gtagaaccgg aaatggtcat
     7261 aggtctaatt gctggtggag aagaagcaat gactgtagct gtcgaagggg ccgaagattc
     7321 ttatgagcta gggcaagaag atctaatcaa gctgaatttg acaaaaaatg atatagttat
     7381 tggtatcgca gctagcggtc gtacaccata tgtgatcggt ggattagatt acgcaaaatc
     7441 gatcggtgct gtcacaggaa cgatttcttg caataaacaa gccgaaatca gtaaacacgc
     7501 ggatttccca atcgaagtcg atgcaggtcc agaatttttg acaggctcta ctcgattgaa
     7561 gtcaggaaca gcacaaaaac ttatcttgaa tatgatttct actatcagta tgattggtat
     7621 aggtaaagta ttcaataact tgatggtcga tgtcaaacca acaaatgaaa aactaatcga
     7681 acgctcaaaa cgaatcatca tgcaagcgac agaagctgat tacgaaacag ctgaaaagta
     7741 ctttgaagaa gcagatcaaa atgttaagct ggctatcgtc atgattttga caaatagtga
     7801 taaagaggaa gctcaagcaa aattagctga agcaaacgga tttgtaaaag ggaccttatg
     7861 agggggaaaa gaccatggca aaaaacgaac tgactttgga agaactggca aaacaaattt
     7921 ataaaggggc aggcggcatg ggcaatgtag aaagcattgt ccactgcatg actcgtgtgc
     7981 gtatgaagat catcaatgat gatcttgtaa atgtctctga attaaaagcg attccaggag
     8041 tgcttggtgt agtagaagat gaacagcttc aagtcatcat cggacctggg aaagtgaaca
     8101 aagtagcaca gcaaatggtt gatttggcag gcgtgaaatt aggagaaaaa ctttcttctg
     8161 taagtacagc tacagcaaat tcatcagcat ctggaaaaga ccgtgtaaac gaacgggcac
     8221 aagaaatgaa agcggcacaa aaatcgaaac aaaaaccatc taaaatcaaa tcggtattaa
     8281 aagacatttc taatatcttt gtgccaatga ttcctgcatt tgtcggtact gggatcgtgg
     8341 cagggattgc cgcagtttta gcaaacttag tcacagccgg aacacttgat gcagcaacat
     8401 ggcaacaata tatcgatgtg atgaacatct tgaaaaacgg gatgtttagc tacctagtta
     8461 tctatacagg tatcaatgct gcacaagttt ttggtgcaac accaactctt ggtggagtta
     8521 tcggggccgt tgtgatgctg acagggatga atccggaagc accactgaaa aacttattta
     8581 ctggtgaagc tcttgcagct ggacaaggtg ggatcctagg tgtcatcttc gctgtttggc
     8641 tattgtcaat cgttgagaaa aaactgcata aagtagtacc tgatgcggta gatatcatcg
     8701 ttacaccaac tctttcattg attgccatcg gtctgattga aattttcttc atcatgcctt
     8761 tagcaggttt catttctgat ggcatggtcg gtgggatcaa ctgggtactt ggcgttggtg
     8821 gagcatttgc cggcttcgtt ctaggcacat tattcttgcc gatggttatg ttcggactgc
     8881 atcaaatttt gactccaatc catgtgcaaa tgattgatga aactggtcgt acgctattgc
     8941 ttccaattct tgcgatggct ggtgcaggac aagtgggtgc agcattggca ttatggattc
     9001 gctgcaaaaa agataaagaa ttaacagaaa tgatcaaagg agctttacca gtcgggatcc
     9061 taggaatcgg cgaaccattg atttacggag taacattacc tctaggacgc ccatttatta
     9121 ctgcttgtat cggtggaggt atcggcgggg cagtgatcgg aatgatcgga aatgtcgggg
     9181 ctatcgctat tggaccttca ggagccgctt tgatcccatt gatctctgac ggtaaatggt
     9241 taggctacat ccttggatta ttggcagctt atgctggtgg cttcgttgct acattcttct
     9301 tcggtattcc taaagaccgt ttagaaaaag aagaattagc gactgaaaca gccacagtaa
     9361 atgaagtgcc tgaaaaagta gtacctcaaa cttcagctga aagtgtgact atcctctcat
     9421 cagttgctga cggaacagtt gtttctttag ataaagcaag tgatccagtt tttgcacaaa
     9481 agatgatggg tgaaggctac tttgtagaac cagaaaacgg acatatctat tctccagtta
     9541 ctggggtagt cagctctgtc ttcccaacga aacacgctat tgggatcaca acgccaaatg
     9601 gtttagaaat cttgcttcat atgggaatca acacagttga cttaggcggt acgccatttg
     9661 atgtgaaagt aacagaaggg cagcaagtga cacctgatac gcttgtagca gaagctgact
     9721 tagaagcgat caaagcagca ggcaaagaaa catccatgat cgtcttggta accaatatgg
     9781 atcgtgtaaa aaactttgtc ttggaaaaaa caggtaaagc aaaagcaaaa gcacctgtga
     9841 tggatgtcaa agcttaatat gatagaaaca atagaaacga aagaagaaac tgaaatctat
     9901 ttttcagctt cttctttttt attatttatt gttttctgct aaaatctgat aaattcgtgt
     9961 cacatcagat ggtgttcccc gtaattcata atctgccaag aaaggaaagc caaatgtttg
    10021 tgcatattgt ttggctgtta gacaatactg attattgaag tttttatttc cgctaccgac
    10081 tacaccaaga caaagtttat gattgtcttc atgttccaga tattcacgca tcgtttcggt
    10141 caagatttct gtatcaccgt tatctaaacc atttccgccg tctaaataag taggaacgaa
    10201 agtaaaaaat ggttctgttt ctttcgtaaa atcactattt tcatggattt cttttaaagt
    10261 aacttcagga ttgacaggat cttctgcatg cattttttca gcatattctg ctagatgttt
    10321 ggcaaaggca cgcgtatttc ctgaaatcga tatatataaa atgttcatgg atcatcctcc
    10381 aattctttcc ttttagtata gcatcttttt taagtttttt ggtggtgtaa tttggaaagg
    10441 gactaggcgc tttgcttgta taatgagaaa aaagccggta gaattatatt tctattaaag
    10501 tttttattaa ttaagtaaaa ataaaaaagg tttgttatac tttttgataa aagcggtttt
    10561 attttggagg atgcttacat ggatacagag caacagaaaa aaggaattgg tttaattcca
    10621 cttgctgcct tagtaattgg ttcagcgatt ggaggtggcg tatttggtat tatgacggac
    10681 atctccggat cggctggcgg cccagctatt ttcagttggg tactcgtagg aacagcaatg
    10741 ttgatgctct ccttgtcgat caataatatc aataaaaaac gtccagattt aaaaggcggg
    10801 atctttagtt acgcagaaga aggttttggc cgtttcgctg gttttatcag cggttggggt
    10861 tactggctca catgctggtt aggcaacgta gcttttgcaa cattgttgat gagcgcatta
    10921 ggatatttct tcccagtatt tgaaggtggg caaaatctgg catcgatcgt gatgagtaca
    10981 gtctttttat ggggatatgc atggctagtg aatcggggag tcgaaaatgc tagtttcgtc
    11041 aatgctatcg tcacattctg taaattagtg ccattatttt tatttattgt agtagctatc
    11101 agcacgtttt cgatccaaca attcattgat aacttttcta gcgacattat attgaatgcg
    11161 aatggacagc cgatcccgtt ttccagtcaa gtattgagtt gcatcatggt gatgctttgg
    11221 gtatttgttg gtattgaagg agcctctgtc gtaggttcac gagcaaaaaa acaatcagat
    11281 gttgggaaag caacgattct agggatattc ggcttgatta ttatttacgt cttggtttcc
    11341 atgcttccat atgggacaat gacgatgaat cagctgcaaa cgatcaaggc gcagcctgct
    11401 atgggctatg tgtttgaaat gatggttggt aaatggggag cagtcgtgat caacggcggt
    11461 ttgatcattt ctttagttgg tgtttggctc tcatggacga tcttaccgat tgaaacaatg
    11521 ggaaacatgg ctgaagacgg acttttgcct aaagcatggg gaaaactcaa caaaaatggg
    11581 gcaccaactt atgctatcgt attgacgacg ttatgtacga atgtcttttt actttcatta
    11641 ttattcactg acagtgctta taactttgct tacacacttg gtacagcagc tattttcttc
    11701 acgtggcttt tcttaggatt gtaccaaatg aaactttctt atcagcggaa agaatgggtc
    11761 caatttttag tagggctttt agcaagtgcc tttcaagtat gggctatgct agtcgtagcc
    11821 tttaatgaag taatgcttgt tcttgttctt ttcttgccag gcatttattt ttacctcaaa
    11881 gcacgtaagg agcaaaacga gcctgtacaa catatccact tagataagat tttacttata
    11941 ggtgtgacga tggtcggagt gattgcaatg gttttatttg ccactgggat gcttcacgta
    12001 tagaagtata aaagaagtat aaagagaggt tgtgagcctg tcgtttattc aaaaacatac
    12061 taggaaagga gctgtgacac aaatgttgtc acagctcctt tttcagaata aacggtgttt
    12121 aagagacagc caatcggcaa taaggctgaa cgtctctttc acagcctctt ttttgatgag
    12181 tcatcataca ttttttcgct taaatacgag atatcctaat gctaagaaca aaacgatgta
    12241 agctaaatta ccgaatagca tttgattagt agaaagatga gtcaattgct tcatgatctc
    12301 ttcgtttcca atttggtttt gcagattcaa catactgatc ggattccatt tgatccactc
    12361 ccatttttgg atgagtgcaa taaggatacc agatatgatt gacgaagcaa aataaaagac
    12421 gattcctgct gagatggatg cgccggaact attgataaag caagcaatca tcaacactaa
    12481 acttaaaatc agccataaac cgatataact acccaaagta taagtgaaca agctttggat
    12541 cagtgtttga ccagtagaaa ccttctccgt gaaggaaatc gaagggaaaa gaatcagttt
    12601 catcaacaca gtgacaataa tagctaaaag gtataaataa acagaataaa taactaatgt
    12661 gatccatttg cttactaata tttctcctcg agaatacttt cgataaagga gatttttcaa
    12721 tgtaccatat tgtgcttcca tcgaaatgat cgtgcttgca gctgcaatca tgataaagac
    12781 aatccaagat gtggcactaa aaagctgagc agtcatttca actggatcaa tgatcgtcgt
    12841 gtattttttg gctagaagtg ctgttcctat gagcaaaaca actaatagaa cagataaaac
    12901 agcagttgac tttttcttga tcaatttaaa taattcttgt tttacaagca atgtcatttt
    12961 tcttcttccc cctttactga atccagaatt tccaatagag aagattccaa atcattcgtc
    13021 agatgctgga cgtctgtcac atggatattt tgtgcagaca atagctggat cacggttcct
    13081 aataattctt cgttttcttt taaaagcttg attttatcag gatcttccaa agtatatcca
    13141 gcttctgtca agatcgttcg agcagctaga tcatttgttg tagagataac gatgaaatct
    13201 tgcgctgttt ggttcaattc agccattgta cattgtttga tgatctttcc ttgattgatc
    13261 aggatcagct catcgaccat tttttcaagc tcgctgagta agtgactgga gatcaagaaa
    13321 gaggtgccct gagtagccaa gtcggtaatg atttttcgca catctcttgt tgcttgtgga
    13381 tccaaaccgt tcatcggctc atctaaaata acgatagacg gatggttcag taaggcaaga
    13441 gcaattccca atttttgttt cattcccaac gagtaggatt tcgctttttt gtgaatgtac
    13501 ttttccatct tgagctgatt cacgatagtg tcgatagcag atacatcgtt ggtttcagag
    13561 aataacttca gatgatcata gcctgttaag aatggataga tacccgggta ttcgatcaat
    13621 gctcctactt gttccaaccc tttatgacta gagggagaaa tctcattttc accaatacag
    13681 attgttccat ctgagtaatg gatcagtcct aaaatagctt tcatgatcgt tgtttttcca
    13741 gcgccattag gacctactaa tccaacgatt ttgccagggg ataagctaaa actgacatcg
    13801 ctgagggctt gtttgtgacc aaagttcttg gataattctt ggaccgaaag acttttcaaa
    13861 aatattcact ccttttctat agatagtaca agcatacacc tgatgagtgg agaagtcgct
    13921 aggtcattgg acttatttct tattttttca taaaaaaatt gaatattaaa taaaaaggct
    13981 tattttttct gatcagtact tattccaagt gtctagtggc cgctagtaat cttgatgcca
    14041 atgatactga tgagtagcat ccccacaaag aaccaagtgg aaagattcag cttatcatga
    14101 aacaagacca caccaattat gaccgaacca actgcgccaa tccctgtcca gataggataa
    14161 gagagactca tcggcaaact tttgattgcc tttgacaaaa agtaaaaact agcaatcatg
    14221 ccaatcactg tgtaaaaaga ataattgatt ttagaaaaac catcactcca tttcatcatc
    14281 gttgaccaga atacttccaa aattcctgct atgattaatt ccatccatgc catacttaca
    14341 ttcctcctta actataaaaa aatacacaaa aagaggaaaa tcatcccttc aaagacctaa
    14401 tggaatgatc atcctcttta tcctacccgg tggcagattg tatatctttt tctgtagtat
    14461 agcacaccta tccagatatc ggcaatctca tactttttag taaagtgtac caagcactga
    14521 cggatatatc gttagcggaa aagaagatga atgctttgca atttcataga aagaagttgt
    14581 tatttattaa tcatttaaaa aaaacagtaa ctagacctta tttctatata ttatcgggca
    14641 ataaattaaa aaaagcttta ccttacaata agtaagataa tttttgtgat aaaaaaataa
    14701 cgaaaaatat ttaaaaatag tgtctatttc gtgagaaaac aactatattt tttatgtgtt
    14761 ttgctttata attaaaaaaa tattgtcatt ttatggagga aaatatatgg aaaattatct
    14821 tagcctttta ggcgtcttga ttgttattct cgggtttgca tttaaattag actcgatatt
    14881 gatcgtaatg gttgctttag ttgttacagc tttgactggc ggtcttggca ttcaaggaat
    14941 gttagaactt ttaggtacaa gttttgtaaa caatcgcggg atggcgattt ttatcatcat
    15001 tatgttggca acaggaacgc ttgaaagaaa tggtctgaaa gaatcagcgg cttccttgat
    15061 caagcgattc aagaaagtat ctgctggtat gattgtagat atttatggga tctttcgaat
    15121 gatctttgcg gcttttaacg tgagttttgg tggagttgct ggatttgttc gtccaatcat
    15181 tttaccgatg gcattgggga ccatcgaatc aaaagggtta gaagtccatc ctaagcatga
    15241 agaagaacta aaaggtatgg cttcagctat ggaaaatgtc tgctggttct ttggccaagt
    15301 actattcatc ggaggagcag gggcgttgct agtccaatca acactgaaag atctaggata
    15361 tgacgtaaca ttgggacagc ttgctttagt ggaagttcca gtggctatca cggctttagt
    15421 tgtggcaagt gtctacttct atcttaaaga aaagaaatta gcgaagaaat attatccagg
    15481 aaaggggcaa taagatggac ttttttacaa atcctgatat tttattaggc gataaattac
    15541 tggagatcct ttatatcgtg atgggactcg tattgattta cactggagta agaaatttaa
    15601 cagataaaac caatcctcat cgttatgggt cagccttttt ctggacggtc ttaggggtag
    15661 ttattgcagg aggaagatgg cttccggcaa tcgtgaacgg tggcttgatc tttgcgatga
    15721 ccataccagc aattgctaag aaagtcagca aaggagaaag ccggcttcca tcaaaagaat
    15781 atatggaaaa aatgtcagac aaactaggaa tgaaaatttt tattccagct ttgagtatcg
    15841 gtgtctttgc gatcttgttt gctctattta ccaatttagg tgctttagtc ggcgtgggcg
    15901 tcggtgtttt tgcagccatg ctaatcttga tgttcttttc tcgagataat cgaccaagta
    15961 catttttaga tgatgcagca gatatgctgg gcacagtagg gccgttaagc atgttgccaa
    16021 tgcttttagc ttctctaggt gcggtattta caagcgctgg agttgggaca gtgatttcca
    16081 atgcagtagg tacgatcgtt ccagaaggaa atgtgaacat cggcatcatc atttacgctc
    16141 ttggcatggt gatatttacg gtaatcatgg ggaatgcatt tgcggccatc accgtgatga
    16201 cggttgggat cggtgcacca ttcgtattta gtcatggagc gaatccagcg ttaataggaa
    16261 tggttgcatt gacttgcggt ttttgtggga ccctgctgac accgatggct gctaacttca
    16321 atatcgtgcc tgtagcgatg ctggagatga aagacaaata cggagtgatc aaaaaccagt
    16381 tgtttattgc gttatttatg ctagttttcc aaattgctta tatgattcta tttaaataat
    16441 agaagagagg ggttgtgaca gaataattgt cgcaacctct tctaacattg tagtggaaca
    16501 ctattttttt ataagaatat attaagtttg atctgttatg ttatttaaac tattgtttcc
    16561 tttatttacg ctgttcaagg aaaatggtat gataaaagat aaccatatgt taaatcaatc
    16621 ggacggagga acaacagatg aaagtactag taacaggttt tgatccattt ggtggggaca
    16681 aagtgaatcc agcctatgaa gcagtaaaaa aaatgccaga tgaaatcagc ggtgctgaaa
    16741 tcatcaaagt ggaagtaccg accgtattcg aaaaaagcag tcaagtagtc aaagaagcca
    16801 tccaacagca ccaaccagat gtcgtgatct gtgtcggaca agcaggtggg cggtcagcag
    16861 tctcgttcga acgtgtcgca atcaatctag cagaagcaag aatccctgat aatgaaggaa
    16921 atcagccatt cgatacggct ttagaagaaa acggtccagc cgcttacttt acctcattgc
    16981 caatcaaagc aatgacaaaa aatgtacaag atcatggtct accagcgtac atctcttata
    17041 cagcaggaac atttgtctgc aatgatatca tgtatcgttt gcttcatttg atcgaaacac
    17101 aattcccggc aattcgaggt gggttcatcc acgtgccatt ctcacccgat caagtgatcg
    17161 atcgtccagt gggtacgcct tctatgtctt tagaagacat tgcttcttct ttgacttatg
    17221 cagttgaagc agcagtagaa aataaagaag atatttccgg aaatgccgga acaactcact
    17281 aatttagcaa gaaacactgg ctggttgcta acgttatgtt agtagccagc tttttgtaat
    17341 tagaaaggaa agaaacagcc gtggaagaat ggcaatccgt ctttgaagaa tggtttccaa
    17401 aagaaatcag caaaagctat cccatcaaaa tttctaaaca atacacaagc agtcaacgtt
    17461 gggagatcta tgcaaaatta acgaaaaaac agcgggaact agtcgataag caccgccgat
    17521 atctaatcag ctctcgtttt atggaagaac attatttagc tgcaacagat tgggtgtttt
    17581 ctgacttcaa gatcaatccg ttttttcgaa caaaacgaag ccagcaaaaa ttgtattgtg
    17641 agtgtggtag agaattaaaa gtgcaataca tcgttaaatc gccaaaaacc ggaaagatcc
    17701 taaaactagg catcaaccac tttgccgatc acctgcatgt ctctccgaca gtggcagctt
    17761 cgatccatca gggaatgaca aaagttgatc tggccttaga cgaattatta tggcttaagc
    17821 agaagaatat cgattttcct gaaggactat ggcaaaaata ctgttttgtc ttgtaccaaa
    17881 atcgtcggat gaaacagcca tatttaccgg atataaaatt agctcagcgg ctcgcagaat
    17941 ttcgccaagt agaaatgccg atttacatag cggattatca agcattggaa aatgaaatca
    18001 agaaaataag tgaacacatc aatgggcagt caaaaaagcg acagataaaa aaagaactat
    18061 ttgacgactt tgcagaagaa ttagtaaagg atgtagaaga attcttgatc aactatcgcg
    18121 catttttacg taaagattgg caatccatcg tatatgaaga agtgccagta catcctaatg
    18181 cttattttga aacatttatt tccgtgttga gaaagacaaa acgtcaacga acaccagaag
    18241 tcactgctca gatggaatat tttgcgaaaa accaacgatt catccaacca aaaatctatc
    18301 tatttatttg gaagcaatat tgtcgctatg gttttacaga agggttcttc gacagcattc
    18361 ctcggatagt cagaaatggt tttttaaaag tattgcgtaa agaacgagaa gctatacaat
    18421 ctgctgataa gaaagaccgt acagtctcaa aagaaaaatg gcaactagta gtgaaagata
    18481 tccaatctgg aaatgtgcaa gagacaatcg acaaatggaa aggaaaacat tatcgtttta
    18541 ctgaagctca gaaacaagcg ttggaatatt atcagaagtt agaagaatca ctgcgtttca
    18601 atgatgaggc aagaaagtat ctgaaggaat tactataaaa aatagaggct gggacagaag
    18661 cgtttaactc caagaaataa gaa
//
LOCUS       DAIGQM010000236        13435 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.073, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000236 DAIGQM010000000
VERSION     DAIGQM010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.073"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..331)
                     /locus_tag="NOA48_002886"
     CDS             complement(<1..331)
                     /locus_tag="NOA48_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0791052.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVE"
     gene            693..1733
                     /locus_tag="NOA48_002887"
     CDS             693..1733
                     /locus_tag="NOA48_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0791053.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1831..2019
                     /locus_tag="NOA48_002888"
     CDS             1831..2019
                     /locus_tag="NOA48_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0791054.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2077..2430)
                     /locus_tag="NOA48_002889"
     CDS             complement(2077..2430)
                     /locus_tag="NOA48_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0791055.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2961..3383
                     /locus_tag="NOA48_002890"
     CDS             2961..3383
                     /locus_tag="NOA48_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0791056.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3380..3610
                     /locus_tag="NOA48_002891"
     CDS             3380..3610
                     /locus_tag="NOA48_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0791057.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4108..4308
                     /locus_tag="NOA48_002892"
     CDS             4108..4308
                     /locus_tag="NOA48_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI0791058.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4335..5528
                     /locus_tag="NOA48_002893"
     CDS             4335..5528
                     /locus_tag="NOA48_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0791059.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5596..7161)
                     /gene="guaA"
                     /locus_tag="NOA48_002894"
     CDS             complement(5596..7161)
                     /gene="guaA"
                     /locus_tag="NOA48_002894"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0791060.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(7220..8143)
                     /locus_tag="NOA48_002895"
     CDS             complement(7220..8143)
                     /locus_tag="NOA48_002895"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0791061.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            8339..8944
                     /locus_tag="NOA48_002896"
     CDS             8339..8944
                     /locus_tag="NOA48_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0791062.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            9252..10268
                     /locus_tag="NOA48_002897"
     CDS             9252..10268
                     /locus_tag="NOA48_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0791063.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            10409..11710
                     /locus_tag="NOA48_002898"
     CDS             10409..11710
                     /locus_tag="NOA48_002898"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0791064.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            11756..12418
                     /gene="deoC"
                     /locus_tag="NOA48_002899"
     CDS             11756..12418
                     /gene="deoC"
                     /locus_tag="NOA48_002899"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0791065.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            12439..12837
                     /locus_tag="NOA48_002900"
     CDS             12439..12837
                     /locus_tag="NOA48_002900"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0791066.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            12903..>13435
                     /locus_tag="NOA48_002901"
     CDS             12903..>13435
                     /locus_tag="NOA48_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0791067.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKG"
BASE COUNT         4407 a         2431 c         2673 g         3924 t
ORIGIN      
        1 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
       61 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
      121 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
      181 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
      241 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
      301 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
      361 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
      421 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
      481 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
      541 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
      601 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
      661 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
      721 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
      781 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
      841 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
      901 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
      961 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     1021 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     1081 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     1141 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     1201 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     1261 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     1321 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     1381 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     1441 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     1501 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     1561 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     1621 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     1681 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     1741 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     1801 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     1861 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     1921 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     1981 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     2041 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     2101 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     2161 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     2221 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     2281 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     2341 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     2401 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     2461 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     2521 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     2581 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     2641 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     2701 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     2761 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     2821 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     2881 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     2941 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     3001 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     3061 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     3121 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     3181 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     3241 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     3301 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     3361 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     3421 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     3481 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     3541 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     3601 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     3661 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     3721 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     3781 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     3841 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     3901 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     3961 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     4021 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     4081 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     4141 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     4201 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     4261 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     4321 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     4381 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     4441 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     4501 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     4561 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     4621 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     4681 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     4741 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     4801 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     4861 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     4921 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     4981 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     5041 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     5101 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     5161 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     5221 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     5281 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     5341 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     5401 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     5461 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     5521 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     5581 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     5641 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     5701 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     5761 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     5821 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     5881 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     5941 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     6001 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     6061 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     6121 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     6181 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     6241 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     6301 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     6361 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     6421 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     6481 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     6541 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     6601 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     6661 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     6721 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     6781 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     6841 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     6901 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     6961 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     7021 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     7081 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
     7141 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
     7201 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
     7261 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
     7321 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
     7381 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
     7441 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
     7501 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
     7561 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
     7621 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
     7681 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
     7741 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
     7801 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
     7861 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
     7921 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
     7981 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
     8041 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
     8101 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
     8161 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
     8221 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
     8281 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
     8341 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
     8401 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
     8461 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
     8521 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
     8581 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
     8641 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
     8701 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
     8761 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
     8821 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
     8881 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
     8941 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
     9001 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
     9061 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
     9121 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
     9181 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
     9241 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
     9301 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
     9361 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
     9421 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
     9481 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
     9541 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
     9601 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
     9661 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
     9721 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
     9781 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
     9841 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
     9901 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
     9961 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    10021 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    10081 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    10141 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    10201 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    10261 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    10321 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    10381 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    10441 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    10501 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    10561 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    10621 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    10681 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    10741 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    10801 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    10861 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    10921 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    10981 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    11041 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    11101 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    11161 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    11221 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    11281 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    11341 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    11401 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    11461 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    11521 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    11581 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    11641 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    11701 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    11761 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    11821 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    11881 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    11941 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    12001 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    12061 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    12121 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    12181 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    12241 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    12301 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    12361 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    12421 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    12481 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    12541 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    12601 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    12661 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    12721 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    12781 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    12841 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    12901 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    12961 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    13021 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    13081 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    13141 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    13201 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    13261 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    13321 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    13381 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaagg
//
LOCUS       DAIGQM010000237         8061 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.091, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000237 DAIGQM010000000
VERSION     DAIGQM010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.091"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            128..1564
                     /locus_tag="NOA48_002902"
     CDS             128..1564
                     /locus_tag="NOA48_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0791068.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="NOA48_002903"
     CDS             1753..4200
                     /locus_tag="NOA48_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI0791069.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="NOA48_002904"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="NOA48_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI0791070.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="NOA48_002905"
     CDS             complement(5690..6793)
                     /locus_tag="NOA48_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0791071.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="NOA48_002906"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="NOA48_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0791072.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2696 a         1375 c         1751 g         2239 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga a
//
LOCUS       DAIGQM010000238         5402 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.106, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000238 DAIGQM010000000
VERSION     DAIGQM010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.106"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            62..1981
                     /gene="tet(M)"
                     /locus_tag="NOA48_002907"
     CDS             62..1981
                     /gene="tet(M)"
                     /locus_tag="NOA48_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI0791073.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2091..2141
                     /locus_tag="NOA48_002908"
                     /pseudo
     CDS             2091..2141
                     /locus_tag="NOA48_002908"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOA48_002909"
     CDS             2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOA48_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI0791074.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            4147..4458
                     /locus_tag="NOA48_002910"
                     /pseudo
     CDS             4147..4458
                     /locus_tag="NOA48_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            4593..5240
                     /locus_tag="NOA48_002911"
     CDS             4593..5240
                     /locus_tag="NOA48_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI0791075.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1813 a          750 c         1042 g         1797 t
ORIGIN      
        1 taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg aggaaaatca
       61 catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa ctaccttaac
      121 agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg acaaaggtac
      181 aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc agacaggaat
      241 aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag gacatatgga
      301 tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc tactgatttc
      361 tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta ggaaaatggg
      421 gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt tatcaacggt
      481 ttatcaggat attaaagaga aactttctat ggaaattata atcaaacaga aagtagagct
      541 gcaccctaat atgtgtgtga tgagctgtac ggaacctgag caatgggatg tggtaataga
      601 aggaaatgat gaccttttag agaaatatat gtccggtaaa tcattagaag cattagaact
      661 cgaacaagag gaaatcagaa gatttcagaa ttgctccttg taccctgttt atcatggaag
      721 cgcaaaaagc aacataggga ttgagcagct tatagaagtg ataacgaata aattttattc
      781 atcaacatac agaaagaagt ctgaactttg cggaaatgtc ttcaaaattg aatattcgga
      841 agaaagacaa cgtcttgcat atgtacgcct ttatggcgga atcctgcatt tgcgggattc
      901 ggttagaata tcggaaaagg aaaaaataaa aattacagaa atgtatactt caataaatgg
      961 tgaattatgt aaaattgata aggcttattc cggggaaatt gttattttgc aaaatgagtt
     1021 tttgaagcta aatagtgttc ttggagatac aaagctattg ccacagagag agagaattga
     1081 aaatccgctc cctctgctgc aaacaactgt tgaaccgagc aaacctcaac aaagggaaat
     1141 gttacttgat gcacttttag aaatctccga cagtgacccg cttctacaat attatgtgga
     1201 ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg aagtgattag
     1261 tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta cagtcattta
     1321 tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc cgccaaatcc
     1381 tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg gaatgcagta
     1441 tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag ttatggaagg
     1501 gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt gtaaaatctg
     1561 ttttaagtat ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc
     1621 tcctattgta ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct
     1681 tagttttaaa atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa
     1741 atattgtgcg aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga
     1801 aatccctgct cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg
     1861 tagtgtttgt ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca
     1921 gccccgtcgt ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta
     1981 gtgtatttta tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta
     2041 ataaagattt gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca
     2101 gggttcaatt aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta
     2161 ttggagggtg aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt
     2221 taatttggct ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct
     2281 cattacctga tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca
     2341 cagcctttat gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat
     2401 taggcatcaa aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg
     2461 ggtttgttgg ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg
     2521 gtgcagctgc atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa
     2581 ataggggtaa agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc
     2641 cagcgattgg tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta
     2701 tgataacaat tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa
     2761 aaggtcattt tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt
     2821 tgtttacaac atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat
     2881 ttgtaaaaca tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata
     2941 taccttttat gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg
     3001 tctctatggt tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa
     3061 gtgtaattat tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac
     3121 ttgttgatag aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta
     3181 gctttttaac tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg
     3241 tatttgtttt aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta
     3301 gcttgaaaca gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat
     3361 cagagggaac aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa
     3421 ggttgttacc tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt
     3481 tttcaggaat cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa
     3541 gggatttcta aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt
     3601 ttataacagg aattcaaatc tttttgttcc attaaagggc gcgattgctg aataaaagat
     3661 acgagagacc tctcttgtat cttttttatt ttgagtggtt ttgtccgtta cactagaaaa
     3721 ccgaaagaca ataaaaattt tattcttgct gagtctggct ttcggtaagc tagacaaaac
     3781 ggacaaaata aaaattggca agggtttaaa ggtggagatt ttttgagtga tcttctcaaa
     3841 aaatactacc tgtcccttgc tgatttttaa acgagcacga gagcaaaacc cccctttgct
     3901 gaggtggcag agggcaggtt tttttgtttc ttttttctcg taaaaaaaag aaaggtctta
     3961 aaggttttat ggttttggtc ggcactgccg acagcctcgc agagcccacc tttacgaagt
     4021 aaagtatagt gtgttatact ttacatggaa gttgtaccga aatattgtgt tgtgaagtct
     4081 atataatttt aaaattatga agtctatata cgtgcgtaaa gatatttaaa gagattaaaa
     4141 ataataaaaa taaaaattga attaaaaaga gatatggttg attattggaa cgattgtttt
     4201 aatgatttac atatattaca accagattgg aaaactatcg aacgtacttc tgatagagca
     4261 atggttttta tgttgttgaa tgatgaagaa gaatggggaa aattagaaag acgtactaag
     4321 aataaatata aaaaattaat taaagaaata tctctaattg atttaactga tttaatgaaa
     4381 tcgactttaa aagcgaacga aaaacaattg caaaagcaga ttgatttttg gcaacgtgaa
     4441 tttagatttt ggaagtaaag taactttgtt ttatacaaaa tgttacttta gtataattaa
     4501 cgtttaagag gtgacacaat atatgaaaaa atcagaggat tattcctcct aaatacaaag
     4561 agataagatg aaatttagga ggaaaattat atatgacttt taatattatt aatttggaaa
     4621 cttgggatag aaaagaatat tttaatcatt atttcaatca acaaacaact tacagtgtta
     4681 ctaaagaatt tgatatcact ttacttaaaa gtatgataaa aaataaagga tatgaactgt
     4741 atcctgcttt gatttataca attgtaaata ttataaatca aaataaagta tttagaacag
     4801 gaattaatag tgagggaaat ttgggttatt gggaaaaatt aaacccttta tatacagtct
     4861 ttaataaaga aactgaaaaa ttttctaaca tttggacaga atcaaatgtt agttttaatt
     4921 ctttttataa tagttataag agtgacttac ttgaatataa agataaaaat gaaatgtttc
     4981 ctaaaaaacc aatacctgaa aacacagttc ctatttcgat gattccttgg attgatttta
     5041 gttcatttaa tttaaatatt ggtaataata gtagattcct attgccaatt attacaatag
     5101 gtaaatttta tagtaagaat aataagatct atttaccagt ctcattgcaa gttcatcatg
     5161 cggtatgtga tggttaccat gtttcattat ttatgagtga atttcaaaat atagttgata
     5221 gtgtaaatga atggatttaa atctaaaata actttcataa acttaagtaa ttatgatatt
     5281 tataagttta tagcaactac catttttggt tgctggtgtt ttgattttga atttggtttt
     5341 gaacttatgg actgatttat tcaggctctt tgtcaaatga tgttggtaaa gagaaatctt
     5401 ag
//
LOCUS       DAIGQM010000239         5099 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.109, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000239 DAIGQM010000000
VERSION     DAIGQM010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.109"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            388..471
                     /locus_tag="NOA48_002912"
     CDS             388..471
                     /locus_tag="NOA48_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI0791076.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            596..1333
                     /gene="erm(B)"
                     /locus_tag="NOA48_002913"
     CDS             596..1333
                     /gene="erm(B)"
                     /locus_tag="NOA48_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0791077.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1596..1712)
                     /locus_tag="NOA48_002914"
     CDS             complement(1596..1712)
                     /locus_tag="NOA48_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI0791078.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            1975..2487
                     /locus_tag="NOA48_002915"
                     /pseudo
     CDS             1975..2487
                     /locus_tag="NOA48_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2559..4172)
                     /locus_tag="NOA48_002916"
     CDS             complement(2559..4172)
                     /locus_tag="NOA48_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0791079.1"
                     /translation="MNEKFARWNVLFIQYVKRDWKKIIVWVLGLGLFSGAFVPAFEEI
                     AKGQGLLGMFETMQNPAMISMVGPTPIKIGTDYTLGAMYAQEMLLFCGLFAMIISALH
                     VVSHTRKEEELGLTELVRSFRVGRQANSLAVISEMLLINLLLGLLIGGLMMSFGVKTI
                     DAEGAFLFGGSIALAGIIGGVLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSN
                     LDLSMFNPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPERE
                     GRATAKKSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQM
                     FTQSGVSIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLY
                     WTTIFLAIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGL
                     AALALGWLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGT
                     IFAVITVISIVFLFVGYLGYKRRDMVEGA"
     gene            complement(4196..5050)
                     /locus_tag="NOA48_002917"
     CDS             complement(4196..5050)
                     /locus_tag="NOA48_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0791080.1"
                     /translation="MQKKFGKFQALKDVSFTVNAGEVVGFIGPNGAGKSTTIRTLLGI
                     INRDEGDVQIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFIKLHGGGSKA
                     KRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVESDLYILDEPTSGLDPLMEAVF
                     QEEVEKIKNDGKAILLSSHILSEVERLADKVAIIRRGEVVETGTLDELRHLTRSTVTL
                     VTEGDIEKLATLSGVHDFVQKDGKATFSADNEAMNTILTEATKLGVTKIESVPPTLED
                     LFMRHYEG"
BASE COUNT         1639 a         1005 c          880 g         1575 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacct tttgtacatt taacttgacg
       61 gtgacatctc tctattgtga gttattagtg gtacagtttt caaccgtttt aattataaaa
      121 aagtggtgca tttttaaatt ggcacaaaca ggtaacggtt attgcaggtg tatttcttat
      181 ctatgggttt aacatggatt ttatcattaa aatcatgagt attgtccgag agtgattggt
      241 cttgcgtatg gttaacccta aagttatgga aataagactt agaagcaaac ttaagagtgt
      301 gttgatagtg cattaaaaat tttgtataat aggaattgaa gttaaattag atgctaaaaa
      361 tttgtaatta agaaggaggg attcgtcatg ttggtattcc aaatgcgtta tgtagataaa
      421 acatctactg ttttgaaaca gactaaaaac agtgattacg cagataaata aatacgttag
      481 attaattcct accagtgact aatcttatga ctttttaaac agataactaa aattacaaac
      541 aaatcgttta acttctgtat ttgtttatag atgtaatcac ttcaggagtg attacatgaa
      601 caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca accaaataat
      661 aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag gtaaagggca
      721 tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat tagacagtca
      781 tctattcaac ttatcgtcag aaaaattaaa actgaatact cgtgtcactt taattcacca
      841 agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg ggagtattcc
      901 ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg cgtctgacat
      961 ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc gaacactagg
     1021 gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag cggaatgctt
     1081 tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata ccacagatgt
     1141 tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca atcgagaata
     1201 tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca aagtaaacaa
     1261 tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc tattatttaa
     1321 cgggaggaaa taattctatg agtcgctttt gtaaatttgg aaagttacac gttactaaag
     1381 ggaatgtaga taaattatta ggtatagggc acctctaata actaccaatt aattcacctc
     1441 aaaatgaaat tagaaaaaaa cagcgaaatt tttaaatcta tttcttatcg atacaaattc
     1501 ctcgtaggcg ctcgggaccc caacatgagg aaatgttttt ataaaaaaag agtagttacc
     1561 gttttttggt aactactctt ttcctttttt aaggtttaaa tacctggaag tttaggtgtt
     1621 ttgggtattg gtggtgtagg tggctgcaag ctttccaatt tttgttgaat tgctttaaat
     1681 tcaggggttt cttggtgttg attttgaacc attttttgct ctattctctc caaagtcggt
     1741 tgaatttctt tccctgatac tttacgattt aattctcttt ctaaggtctc tttcggacta
     1801 atggaaggcg tttctaagct tgaatagagt ttcactcctt ctctattgta aagccttata
     1861 tcgctaaata agcccgtttt atgaagggtt tctaaattgg tcggtaagtt tttgacaaca
     1921 atatcatgcg cttgttttgg tggtgcccta gctgtcattg gatcatctgc atacaataag
     1981 atccatgaaa ggccatctgc tgccaatgag cgccttgaga ttggtaattg ggaagctgat
     2041 actgtagccg gtaaaacagg tagggctcgt attgtaactc tagtcgatcg tagatctcgt
     2101 ttctccctac ttggtaaggt tgaaaagaaa atctctaaaa atgtggttga ttgtatgatc
     2161 aatctactaa gaaatgtagg agaagataaa tgtaaaaccg ttacacccga tagaggaaaa
     2221 gaattctccc aacatagtcg aataacgcta gaattaaatg gcactaaagt gtattttcca
     2281 gatccacatg ctccatggca acgtggtaca aacgaaaata ctaatggttt attacgagaa
     2341 tattcaccca aaggtgaaga tatttcaggt attttcgata gtcaaattca agaatgggcg
     2401 aataaattaa acacgcgacc acggaaatgt ctaaattgga aaacccctta tgaagtattt
     2461 tttaatgaat cgttgcactt aatttgacaa ttgaagccat aaaaaaaccg ctcaaatcga
     2521 ctttcgtaaa tatgaacggt tttttagaaa ttcaattttt aagcgccttc taccatatca
     2581 cggcgtttgt atcctaaata gccgacaaat aagaagacga tactgataac agtaattact
     2641 gcaaaaatcg ttccatcaaa tttttccatc ggtaagcgtg gaatccaact ttgaattgca
     2701 gtttttgaga accaatccgg caaatctaag attccgccga aataattcaa agcaaaggaa
     2761 tagcctagat aagcatagat tacttttcca aattttggca accagcctaa cgctaaagca
     2821 gccaaaccaa tataaaataa gatggaaggg agaaaattgt atccagcagc taagaaatcg
     2881 gtcagatcca tagtcgattc atttttcatc gcagaaatcg ccgttccacc taatcccgct
     2941 gatgctaagc caatacctac gactccagca aaaatagcta aaaatatcgt tgtccaatat
     3001 aattggcctc gcgtaatctt cgttacatac agttgactca gatgcagtct tgtttcttct
     3061 gcaaataatt tattgaccac cgcgattggc aagattgtga ctaatccaat cattaccatc
     3121 atgatcgttg ccgtaaagga ttcttcaatg gaaacgccag attgagtgaa catttgtttc
     3181 atcagttcat ttccgccaag aaagacttgc atgtctccat aaatggagcc atacgcagct
     3241 cccataacga caaatgcgat cagccaacca atcattactc ctttattaat cttgaaaaac
     3301 aaaccaggta cagaaagtag tgatttcttc gccgtcgcac gtccttctcg ttcaggaaga
     3361 taacctgcgc ccatgtcgcg atgttcttcc aacacaaacg caagtacggt aaaaacaaga
     3421 ctaaaaatca aagcaaataa taatggtagc cagttatttt ctgtgaaagg ataggtcaag
     3481 taaatccatc ccattggatt gaacattgat aaatcaagat tagacacatc tgttccagcg
     3541 cgcacgatat acaaaagtcc tataagactt aatgtcgagc cggttgctcc agtagaagtc
     3601 gccataatct gcgacatcac aagtgccaat acaccaccga taattcccgc caatgcaatt
     3661 gatcctccga acaagaaagc tccttcggca tcaatcgttt ttacaccaaa actcatcatg
     3721 agtccgccga ttaaaagacc taataaaaga ttgatcaaca gcatctcact gataacagct
     3781 aatgaattgg cttgtcgtcc tactcgaaat gagcgaacca attcagtcaa acctaattct
     3841 tcttcttttc gcgtgtggct caccacatga agtgctgaga taatcattgc gaacaatccg
     3901 caaaacagca acatctcttg agcatacatc gctcctaaag tataatccgt acctattttg
     3961 attggtgtag gtccaaccat cgagatcatc gctggatttt gcatcgtttc aaacatccct
     4021 aaaagacctt gtcctttagc aatctcttca aatgctggta caaatgctcc tgagaacaaa
     4081 cccaaaccta aaacccaaac aattattttt ttccaatcgc gtttcacgta ttgaatgaac
     4141 aatacgttcc aacgggcaaa tttttcattc attttctttt cctccgttcc gacaatcagc
     4201 cttcgtaatg acgcatgaat agatcttcaa gcgttggcgg tacagattcg atttttgtca
     4261 cacctaattt ggttgcctcg gtcagaatcg tattcatcgc ttcattgtca gcagaaaaag
     4321 ttgctttgcc gtctttttga acaaaatcat gcacgccaga gagcgtcgca agtttctcaa
     4381 tatcgccttc tgtcaccaat gtaactgttg agcgagtcaa atgacgcaat tcatctaatg
     4441 tacctgtttc aactacttct ccacgtcgaa tgattgctac tttatctgct aatcgttcaa
     4501 cttcacttaa aatatgtgaa gataatagaa tcgctttgcc atcatttttg attttttcta
     4561 cttcttcttg gaatactgct tccatcaatg gatctagtcc tgaagtcggt tcatctaaaa
     4621 tatacagatc agattcaact gaaagtgcag caatcaaacc gactttttga cgatttcctt
     4681 tagagtaacc tttggctttt ttctttggat caagttcaaa tcgtttgatt aaataatcgc
     4741 gctttgcttt gctcccgccg ccatgaagtt tgataaatag atcaatgatc tctccaccag
     4801 tcaggctgcc ccaaagagca acatctccag gaacatacga aattcgttta tggatttcta
     4861 gactatcttt ccaaacatct tttccgaata tttggacatc tccttcgtct ctgttgatga
     4921 ttcctagcag tgtacggatc gtcgttgact ttcctgctcc atttggtccg ataaaaccaa
     4981 caacttcacc ggcgtttact gtgaatgaga catctttcaa cgcctggaat ttaccaaatt
     5041 ttttttgcaa gccttgtact ggttctgttg caaagtttta aataaagaat aaaatccct
//
LOCUS       DAIGQM010000240         4374 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.122, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000240 DAIGQM010000000
VERSION     DAIGQM010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.122"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            245..1213
                     /locus_tag="NOA48_002918"
     CDS             245..1213
                     /locus_tag="NOA48_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0791081.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="NOA48_002919"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="NOA48_002919"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0791082.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="NOA48_002920"
     CDS             2243..2851
                     /locus_tag="NOA48_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0791083.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /gene="vanY"
                     /locus_tag="NOA48_002921"
     CDS             3279..4190
                     /gene="vanY"
                     /locus_tag="NOA48_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI0791084.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1383 a          775 c         1011 g         1205 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacta tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatgg ttctgttgca aagttttaaa taaagaataa aatc
//
LOCUS       DAIGQM010000241         3643 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.135, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000241 DAIGQM010000000
VERSION     DAIGQM010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.135"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            complement(<1..164)
                     /locus_tag="NOA48_002922"
     CDS             complement(<1..164)
                     /locus_tag="NOA48_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0791085.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELC"
     gene            394..891
                     /gene="dfrG"
                     /locus_tag="NOA48_002923"
     CDS             394..891
                     /gene="dfrG"
                     /locus_tag="NOA48_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0791086.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(963..2915)
                     /locus_tag="NOA48_002924"
     CDS             complement(963..2915)
                     /locus_tag="NOA48_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0791087.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2922..3158)
                     /locus_tag="NOA48_002925"
     CDS             complement(2922..3158)
                     /locus_tag="NOA48_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0791088.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            complement(3393..>3643)
                     /locus_tag="NOA48_002926"
     CDS             complement(3393..>3643)
                     /locus_tag="NOA48_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0791089.1"
                     /translation="LEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDN
                     LIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
BASE COUNT         1128 a          629 c          587 g         1299 t
ORIGIN      
        1 ttacataatt caccatttat tgaagtatac atttctgtaa cttttatttt ttctttttct
       61 gatactctaa ccgaatctcg taaatgtagt actccactat aaaggcgtat atatgcaagt
      121 aagtagttca gttttggagt acaaaatgac aaaatgtact tcaaaatgga ctactttttt
      181 cattttaact tacataccaa attacataca aaatgattta taaaatgcaa ttgaaaatga
      241 taattgaatg aaaatttgtg attttgtggt attatgataa tataacttat agaaaaaatt
      301 gcttattcaa ctaacgggca ggataatgag aaaaggtttt ttgatagaaa taagaaatta
      361 gatggtaaat tagttaaaaa ggctgtgtta taaatgaaag tttctttgat tgctgcgatg
      421 gataagaata gagtgattgg caaagagaat gacattcctt ggaggattcc caaggactgg
      481 gaatatgtta aaaatactac aaagggacat ccgataatat taggtaggaa gaaccttgaa
      541 tcaatcggaa gagccttacc tgacagaaga aatattattc tgacgagaga taaggggttt
      601 acctttaatg gttgtgaaat tgttcattca atagaagatg tttttgagtt atgtaaaaac
      661 gaagaagaaa tttttatttt cggaggagaa cagatttata atttgttttt cccttatgtt
      721 gagaaaatgt acatcacaaa aatacatcat gaattcgaag gagatacttt ttttccagaa
      781 gtgaattatg aggaatggaa tgaggtattt gcccaaaaag ggataaagaa tgataaaaat
      841 ccgtataact actattttca tgtatatgaa agaaaaaact tattgagtta acgggtgcgt
      901 taattgaaga agaacagtaa agataaagca caagagcttg ggattactcc aagctctttt
      961 tgtcatttga aataaattat atctttccaa tcaaattgtt tatctgtaat ccctaatctt
     1021 tgagcaggtg tcaaaacctt tttatccgct gatttaaaag ggcgacaaaa gttgtagtaa
     1081 gttcttagaa ttgtaatcgc aaattgagca tacttcggat tgaagttagc gtaaatatag
     1141 ctcttcttat caccacgagc tgttgttaat ggtctttcaa gagatgatat ataacgtctt
     1201 atctgttgaa taaagctatt ggtcgaatgg tcattaacat ttaatagcat ctttgcgatt
     1261 tcgtttggtt ccagagcaga taaatccgtt ctacaatcaa ctgaataaaa tcctttatcc
     1321 ttagtggcta atggatgttt gatagggtta tcggcatatt tgcgatatct ttctccatct
     1381 ttactaatag cctcttcgtg gaattgatga cttgttagta attcagttag ataatgagat
     1441 gccaaagtcc gtagaaactt tgttttgaat cctctgatat ctccccaatc gagcagttct
     1501 gcttttgctt gtccgaattc ttttaagcat tgttttctgc ttttcgtctt gttaacttgg
     1561 caaataaaat gatgtgcatc gctcaacctt aattctttcg tgaatactct ataaaaggcg
     1621 tttctaatag agaagtcatc atcactaatc attcgccatt cgtcggcatt aaccatttgt
     1681 ttaattaacc aatagtgagc agttgtagta taaggagcat caacatttaa accatcgaca
     1741 aatctactcc tattagtaat tttccctaat tcgtgaagat aagcattcct attttcgcta
     1801 tcgttagcgg atggttcttg tggataataa gaccaatcta acctatcatt tttacgacta
     1861 aaagtattga gatggtcttc tttgaatttt cttgtatctt catttaattc atccattgaa
     1921 atattccaat cataggcaac atcagaacgg aacacatatc ttgataagac ctcagcagat
     1981 acaactatat acgtttgcat attaaggtct tcaaaccccg tatatttctt tgaaccttgt
     2041 cctttcttac ggacgttatt taggtagtag tgcatcttgt ccgtattaag ccacatctcg
     2101 ttaaatttct ttgtttgaag gggttgtgtc tcatatcgtt ctaaaaactc caaacaacgc
     2161 ctatacagcc actccagctt atgatagtag gttccaactc caattcctaa aatatcacaa
     2221 gtacgactga ctgaaaccct tccaacaacc atcttagcga acattggaag aatggtgttc
     2281 ttttgttggt gataagtagt ggtttcttct ctttttggta gaacattagt gaacttctta
     2341 cacgccttac attgatagcg ttgagatttg cccctacttt tccccctttt gtaaaattgc
     2401 ttcggctcat tgaatggggt tgattcttct tccgagcagc cttctttatg aaattgataa
     2461 tctggctcaa catcttggat gctattgatt tctataaggc gtttaatttc ttcaacaaca
     2521 gaccaattag ataaaggggt tactgtacag ttttgcgata cacctctgcc aataggattg
     2581 tcattgcagt acataccttt atgaccttta tctttggaac taccagtcat tttatatcga
     2641 cttggtttcc cttttacatc tttgaatttg tgctgttctt tcccaaaatt acaacaaaac
     2701 ggattgatgc agtaattata ttgaatggga tattcagaac cgttccattt aaaagacgtt
     2761 ggcaagaaca acattttgtt ataccttgtt gcaaatcgtt ttggagttaa taaatcatat
     2821 tgtttagccc tatcttttaa ttcttcgttt gaaatcggaa ttttaacatc tacaatttca
     2881 tcttccttcg tggctaatct tttaagcttg gtcattgtct atcaacccac tctatctttg
     2941 atacccattt tttcaacaat ccgcttatta cttcgcttgt tggcaatcca ttcaataaac
     3001 ttcttatcgt ctaaaatgtt caataagaat tcatccactg cttcgctttc agtacgctct
     3061 gcatattcag cgtattgctt aactatcacc cttacttgct ctgatatttc ccaatccaca
     3121 gacttagcgt tcttattttt tggctcaaga aattgcatag gaaaatgcac ccctttttgc
     3181 ttagtaaatt gtaaccattt taacacacca atttgcattc ctacaataat tatttcacgt
     3241 tcgcattttt atatacattt taacttacat tttgtggtgt aaattaacaa caaacgttga
     3301 tttaacaata aaaaacgagt atcaaattca gttgcaattt gatactcatt taggtttaca
     3361 ttttcacttt ttgtactcca aaactgaact acttaatatg caagacgttg tctttttttt
     3421 gtatattcaa ttttgaaaac atttccgcaa agttcagacg gacctcgatg tgttgatgaa
     3481 taaaatttat tagtaataac ttctataagg ttatcaatcc ctatattact ttttgcactt
     3541 ccatgataaa gagggaacag agaacaattc tgaaatctta tgctttcctc ttgttcgagt
     3601 tccaatgctt ctaatgattt accggacata tatttctcta aaa
//
LOCUS       DAIGQM010000242         2208 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.147, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000242 DAIGQM010000000
VERSION     DAIGQM010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.147"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..115
                     /locus_tag="NOA48_002927"
     CDS             <1..115
                     /locus_tag="NOA48_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0791090.1"
                     /translation="LFDSRFKTLQQNPVNQICEITNVSRASLYRKLSEVNN"
     gene            329..1024
                     /gene="vanR"
                     /locus_tag="NOA48_002928"
     CDS             329..1024
                     /gene="vanR"
                     /locus_tag="NOA48_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0791091.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1002..2156
                     /locus_tag="NOA48_002929"
     CDS             1002..2156
                     /locus_tag="NOA48_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0791092.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          740 a          408 c          467 g          593 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccct gtaaatcaaa tttgtgaaat
       61 tactaatgta tctagggctt cattatacag gaaattatca gaagtgaata attagccatt
      121 ctgtattccg ctaatgggca atatttttaa agaagaaaag gaaactataa aatattaaca
      181 gcctcctagc gatgccgaaa agccctttga taaaaaaaga atcatcatct taagaaattc
      241 ttagtcattt attatgtaaa tgcttataaa ttcggcccta taatctgata aattattaag
      301 ggcaaactta tgtgaaaggg tgataactat gagcgataaa atacttattg tggatgatga
      361 acatgaaatt gccgatttgg ttgaattata cttaaaaaac gagaattata cggttttcaa
      421 atactatacc gccaaagaag cattggaatg tatagacaag tctgagattg accttgccat
      481 attggacatc atgcttcccg gcacaagcgg ccttactatc tgtcaaaaaa taagggacaa
      541 gcacacctat ccgattatca tgctgaccgg gaaagataca gaggtagata aaattacagg
      601 gttaacaatc ggcgcggatg attatataac gaagcccttt cgcccactgg agttaattgc
      661 tcgggtaaag gcccagttgc gccgatacaa aaaattcagt ggagtaaagg agcagaacga
      721 aaatgttatc gtccactccg gccttgtcat taatgttaac acccatgagt gttatctgaa
      781 cgagaagcag ttatccctta ctcccaccga gttttcaata ctgcgaatcc tctgtgaaaa
      841 caaggggaat gtggttagct ccgagctgct atttcatgag atatggggcg acgaatattt
      901 cagcaagagc aacaacacca tcaccgtgca tatccggcat ttgcgcgaaa aaatgaacga
      961 caccattgat aatccgaaat atataaaaac ggtatggggg gttggttata aaattgaaaa
     1021 ataaaaaaaa cgactattcc aaactagaac gaaaacttta catgtatatc gttgcaattg
     1081 ttgtggtagc aattgtattc gtgttgtata ttcgttcaat gatccgaggg aaacttgggg
     1141 attggatctt aagtattttg gaaaacaaat atgacttaaa tcacctggac gcgatgaaat
     1201 tatatcaata ttccatacgg aacaatatag atatctttat ttatgtggcg attgtcatta
     1261 gtattcttat tctatgtcgc gtcatgcttt caaaattcgc aaaatacttt gacgagataa
     1321 ataccggcat tgatgtactt attcagaacg aagataaaca aattgagctt tctgcggaaa
     1381 tggatgttat ggaacaaaag ctcaacacat taaaacggac tctggaaaag cgagagcagg
     1441 atgcaaagct ggccgaacaa agaaaaaatg acgttgttat gtacttggcg cacgatatta
     1501 aaacgcccct tacatccatt atcggttatt tgagcctgct tgacgaggct ccagacatgc
     1561 cggtagatca aaaggcaaag tatgtgcata tcacgttgga caaagcgtat cgactcgaac
     1621 agctaatcga cgagtttttt gagattacac ggtataacct acaaacgata acgctaacaa
     1681 aaacgcacat agacctatac tatatgctgg tgcagatgac cgatgaattt tatcctcagc
     1741 tttccgcaca tggaaaacag gcggttattc acgcccccga ggatctgacc gtgtccggcg
     1801 accctgataa actcgcgaga gtctttaaca acattttgaa aaacgccgct gcatacagtg
     1861 aggataacag catcattgac attaccgcgg gcctctccgg ggatgtggtg tcaatcgaat
     1921 tcaagaacac tggaagcatc ccaaaagata agctagctgc catatttgaa aagttctata
     1981 ggctggacaa tgctcgttct tccgatacgg gtggcgcggg acttggattg gcgattgcaa
     2041 aagaaattat tgttcagcat ggagggcaga tttacgcgga aagcaatgat aactatacga
     2101 cgtttagggt agagcttcca gcgatgccag acttggttga taaaaggagg tcctaagaga
     2161 tgtatataat tttggctctt tgtcaaatga tgttggtaaa gagaaatc
//
LOCUS       DAIGQM010000243         1402 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.159, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000243 DAIGQM010000000
VERSION     DAIGQM010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.159"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            <1..1311
                     /locus_tag="NOA48_002930"
     CDS             <1..1311
                     /locus_tag="NOA48_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HCI0791093.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          598 a          107 c          236 g          461 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat tcaaaatctt
     1381 tcagagaagc tgttaaagga at
//
LOCUS       DAIGQM010000244         1247 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate
            V002116ENTFAE SAMN29456638-rid14859173.guided.167, whole genome
            shotgun sequence.
ACCESSION   DAIGQM010000244 DAIGQM010000000
VERSION     DAIGQM010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456638
            Sequence Read Archive: SRR19916869
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361144.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361144.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:13:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,932
            CDSs (total)                      :: 2,868
            Genes (coding)                    :: 2,780
            CDSs (with protein)               :: 2,780
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 5 (16S, 23S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 41 of 88
            Pseudo Genes (incomplete)         :: 35 of 88
            Pseudo Genes (internal stop)      :: 27 of 88
            Pseudo Genes (multiple problems)  :: 13 of 88
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456638-rid14859173.guided.167"
                     /strain="microbial"
                     /isolate="V002116ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2020-09-26"
     gene            47..439
                     /locus_tag="NOA48_002931"
     CDS             47..439
                     /locus_tag="NOA48_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0791094.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            440..>1247
                     /gene="aac(6')-Ie"
                     /locus_tag="NOA48_002932"
     CDS             440..>1247
                     /gene="aac(6')-Ie"
                     /locus_tag="NOA48_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HCI0791095.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDEL"
BASE COUNT          508 a           99 c          215 g          425 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tggtggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     1201 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattat
//
